Michel Goedert, PhD - Publications

Affiliations: 
Medical Research Council University of Cambridge, Cambridge, England, United Kingdom 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=9
Website:
http://www.neuroscience.cam.ac.uk/directory/profile.php?migo

262 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Holtzman DM, Carrillo MC, Hendrix JA, Bain LJ, Catafau AM, Gault LM, Goedert M, Mandelkow E, Mandelkow EM, Miller DS, Ostrowitzki S, Polydoro M, Smith S, Wittmann M, Hutton M. Tau: From research to clinical development. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27154059 DOI: 10.1016/j.jalz.2016.03.018  0.56
2016 Jackson SJ, Kerridge C, Cooper J, Cavallini A, Falcon B, Cella CV, Landi A, Szekeres PG, Murray TK, Ahmed Z, Goedert M, Hutton M, O'Neill MJ, Bose S. Short Fibrils Constitute the Major Species of Seed-Competent Tau in the Brains of Mice Transgenic for Human P301S Tau. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 762-72. PMID 26791207 DOI: 10.1523/JNEUROSCI.3542-15.2016  0.56
2015 Gauthier S, Albert M, Fox N, Goedert M, Kivipelto M, Mestre-Ferrandiz J, Middleton LT. "Why therapy development for dementia has failed in the last two decades?" Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26710325 DOI: 10.1016/j.jalz.2015.12.003  0.56
2015 Goedert M, Cheng Y. Parkinson's disease: Crystals of a toxic core. Nature. 525: 458-9. PMID 26352470 DOI: 10.1038/nature15630  0.56
2015 Goedert M, Spillantini MG, Crowther RA. A Brief History of Tau. Clinical Chemistry. 61: 1417-8. PMID 26330509 DOI: 10.1373/clinchem.2015.245142  0.56
2015 Goedert M. NEURODEGENERATION. Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein. Science (New York, N.Y.). 349: 1255555. PMID 26250687 DOI: 10.1126/science.1255555  0.56
2015 Brelstaff J, Ossola B, Neher JJ, Klingstedt T, Nilsson KP, Goedert M, Spillantini MG, Tolkovsky AM. The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice. Frontiers in Neuroscience. 9: 184. PMID 26074756 DOI: 10.3389/fnins.2015.00184  0.56
2015 Klingstedt T, Shirani H, Mahler J, Wegenast-Braun BM, Nyström S, Goedert M, Jucker M, Nilsson KP. Distinct Spacing Between Anionic Groups: An Essential Chemical Determinant for Achieving Thiophene-Based Ligands to Distinguish β-Amyloid or Tau Polymorphic Aggregates. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 9072-82. PMID 26013403 DOI: 10.1002/chem.201500556  0.56
2015 Duyckaerts C, Braak H, Brion JP, Buée L, Del Tredici K, Goedert M, Halliday G, Neumann M, Spillantini MG, Tolnay M, Uchihara T. PART is part of Alzheimer disease. Acta Neuropathologica. 129: 749-56. PMID 25628035 DOI: 10.1007/s00401-015-1390-7  0.56
2015 Ghetti B, Oblak AL, Boeve BF, Johnson KA, Dickerson BC, Goedert M. Invited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimaging. Neuropathology and Applied Neurobiology. 41: 24-46. PMID 25556536 DOI: 10.1111/nan.12213  0.56
2015 Falcon B, Cavallini A, Angers R, Glover S, Murray TK, Barnham L, Jackson S, O'Neill MJ, Isaacs AM, Hutton ML, Szekeres PG, Goedert M, Bose S. Conformation determines the seeding potencies of native and recombinant Tau aggregates. The Journal of Biological Chemistry. 290: 1049-65. PMID 25406315 DOI: 10.1074/jbc.M114.589309  0.56
2015 Clavaguera F, Hench J, Goedert M, Tolnay M. Invited review: Prion-like transmission and spreading of tau pathology. Neuropathology and Applied Neurobiology. 41: 47-58. PMID 25399729 DOI: 10.1111/nan.12197  0.56
2014 Xu H, Rösler TW, Carlsson T, de Andrade A, Fiala O, Hollerhage M, Oertel WH, Goedert M, Aigner A, Höglinger GU. Tau silencing by siRNA in the P301S mouse model of tauopathy. Current Gene Therapy. 14: 343-51. PMID 25687501  0.56
2014 Höllerhage M, Deck R, De Andrade A, Respondek G, Xu H, Rösler TW, Salama M, Carlsson T, Yamada ES, Gad El Hak SA, Goedert M, Oertel WH, Höglinger GU. Piericidin A aggravates Tau pathology in P301S transgenic mice. Plos One. 9: e113557. PMID 25437199 DOI: 10.1371/journal.pone.0113557  0.56
2014 Goedert M, Falcon B, Clavaguera F, Tolnay M. Prion-like mechanisms in the pathogenesis of tauopathies and synucleinopathies. Current Neurology and Neuroscience Reports. 14: 495. PMID 25218483 DOI: 10.1007/s11910-014-0495-z  0.56
2014 Flach K, Ramminger E, Hilbrich I, Arsalan-Werner A, Albrecht F, Herrmann L, Goedert M, Arendt T, Holzer M. Axotrophin/MARCH7 acts as an E3 ubiquitin ligase and ubiquitinates tau protein in vitro impairing microtubule binding. Biochimica Et Biophysica Acta. 1842: 1527-38. PMID 24905733 DOI: 10.1016/j.bbadis.2014.05.029  0.56
2014 Herva ME, Zibaee S, Fraser G, Barker RA, Goedert M, Spillantini MG. Anti-amyloid compounds inhibit α-synuclein aggregation induced by protein misfolding cyclic amplification (PMCA). The Journal of Biological Chemistry. 289: 11897-905. PMID 24584936 DOI: 10.1074/jbc.M113.542340  0.56
2014 Ahmed Z, Cooper J, Murray TK, Garn K, McNaughton E, Clarke H, Parhizkar S, Ward MA, Cavallini A, Jackson S, Bose S, Clavaguera F, Tolnay M, Lavenir I, Goedert M, et al. A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity. Acta Neuropathologica. 127: 667-83. PMID 24531916 DOI: 10.1007/s00401-014-1254-6  0.56
2014 Clavaguera F, Hench J, Lavenir I, Schweighauser G, Frank S, Goedert M, Tolnay M. Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice. Acta Neuropathologica. 127: 299-301. PMID 24362441 DOI: 10.1007/s00401-013-1231-5  0.56
2014 Iovino M, Pfisterer U, Holton JL, Lashley T, Swingler RJ, Calo L, Treacy R, Revesz T, Parmar M, Goedert M, Muqit MM, Spillantini MG. The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons. Acta Neuropathologica. 127: 283-95. PMID 24292008 DOI: 10.1007/s00401-013-1219-1  0.56
2013 Mellone M, Kestoras D, Andrews MR, Dassie E, Crowther RA, Stokin GB, Tinsley J, Horne G, Goedert M, Tolkovsky AM, Spillantini MG. Tau pathology is present in vivo and develops in vitro in sensory neurons from human P301S tau transgenic mice: a system for screening drugs against tauopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18175-89. PMID 24227726 DOI: 10.1523/JNEUROSCI.4933-12.2013  0.56
2013 Jenner P, Morris HR, Robbins TW, Goedert M, Hardy J, Ben-Shlomo Y, Bolam P, Burn D, Hindle JV, Brooks D. Parkinson's disease--the debate on the clinical phenomenology, aetiology, pathology and pathogenesis. Journal of Parkinson's Disease. 3: 1-11. PMID 23938306 DOI: 10.3233/JPD-130175  0.56
2013 Hastings MH, Goedert M. Circadian clocks and neurodegenerative diseases: time to aggregate? Current Opinion in Neurobiology. 23: 880-7. PMID 23797088 DOI: 10.1016/j.conb.2013.05.004  0.56
2013 Klingstedt T, Shirani H, Ã…slund KO, Cairns NJ, Sigurdson CJ, Goedert M, Nilsson KP. The structural basis for optimal performance of oligothiophene-based fluorescent amyloid ligands: conformational flexibility is essential for spectral assignment of a diversity of protein aggregates. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 10179-92. PMID 23780508 DOI: 10.1002/chem.201301463  0.56
2013 Clavaguera F, Akatsu H, Fraser G, Crowther RA, Frank S, Hench J, Probst A, Winkler DT, Reichwald J, Staufenbiel M, Ghetti B, Goedert M, Tolnay M. Brain homogenates from human tauopathies induce tau inclusions in mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 110: 9535-40. PMID 23690619 DOI: 10.1073/pnas.1301175110  0.56
2013 Spillantini MG, Goedert M. Tau pathology and neurodegeneration. The Lancet. Neurology. 12: 609-22. PMID 23684085 DOI: 10.1016/S1474-4422(13)70090-5  0.56
2013 Ozcelik S, Fraser G, Castets P, Schaeffer V, Skachokova Z, Breu K, Clavaguera F, Sinnreich M, Kappos L, Goedert M, Tolnay M, Winkler DT. Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice. Plos One. 8: e62459. PMID 23667480 DOI: 10.1371/journal.pone.0062459  0.56
2013 Clavaguera F, Lavenir I, Falcon B, Frank S, Goedert M, Tolnay M. "Prion-like" templated misfolding in tauopathies. Brain Pathology (Zurich, Switzerland). 23: 342-9. PMID 23587140 DOI: 10.1111/bpa.12044  0.56
2013 Morris KL, Zibaee S, Chen L, Goedert M, Sikorski P, Serpell LC. The structure of cross-β tapes and tubes formed by an octapeptide, αSβ1. Angewandte Chemie (International Ed. in English). 52: 2279-83. PMID 23307646 DOI: 10.1002/anie.201207699  0.56
2013 Goedert M, Spillantini MG, Del Tredici K, Braak H. 100 years of Lewy pathology. Nature Reviews. Neurology. 9: 13-24. PMID 23183883 DOI: 10.1038/nrneurol.2012.242  0.56
2012 Schön C, Hoffmann NA, Ochs SM, Burgold S, Filser S, Steinbach S, Seeliger MW, Arzberger T, Goedert M, Kretzschmar HA, Schmidt B, Herms J. Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice. Plos One. 7: e53547. PMID 23300938 DOI: 10.1371/journal.pone.0053547  0.56
2012 Schaeffer V, Goedert M. Stimulation of autophagy is neuroprotective in a mouse model of human tauopathy. Autophagy. 8: 1686-7. PMID 22874558 DOI: 10.4161/auto.21488  0.56
2012 Schaeffer V, Lavenir I, Ozcelik S, Tolnay M, Winkler DT, Goedert M. Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy. Brain : a Journal of Neurology. 135: 2169-77. PMID 22689910 DOI: 10.1093/brain/aws143  0.56
2012 Bull ND, Guidi A, Goedert M, Martin KR, Spillantini MG. Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau. Plos One. 7: e34724. PMID 22496848 DOI: 10.1371/journal.pone.0034724  0.56
2012 Goedert M, Ghetti B, Spillantini MG. Frontotemporal dementia: implications for understanding Alzheimer disease. Cold Spring Harbor Perspectives in Medicine. 2: a006254. PMID 22355793 DOI: 10.1101/cshperspect.a006254  0.56
2012 Yoshida H, Goedert M. Phosphorylation of microtubule-associated protein tau by AMPK-related kinases. Journal of Neurochemistry. 120: 165-76. PMID 21985311 DOI: 10.1111/j.1471-4159.2011.07523.x  0.56
2012 Goedert M, Spillantini MG. Synucleinopathies and Tauopathies Basic Neurochemistry. 829-843. DOI: 10.1016/B978-0-12-374947-5.00047-X  0.56
2011 Goedert M, Spillantini MG. Pathogenesis of the tauopathies. Journal of Molecular Neuroscience : Mn. 45: 425-31. PMID 21785996 DOI: 10.1007/s12031-011-9593-4  0.56
2011 Gasparini L, Crowther RA, Martin KR, Berg N, Coleman M, Goedert M, Spillantini MG. Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability. Neurobiology of Aging. 32: 419-33. PMID 19356824 DOI: 10.1016/j.neurobiolaging.2009.03.002  0.56
2011 Ghetti B, Wszolek ZK, Boeve BF, Spina S, Goedert M. Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 Neurodegeneration: the Molecular Pathology of Dementia and Movement Disorders: Second Edition. 110-134. DOI: 10.1002/9781444341256.ch14  0.56
2011 Goedert M. Introduction to the Tauopathies Neurodegeneration: the Molecular Pathology of Dementia and Movement Disorders: Second Edition. 103-109. DOI: 10.1002/9781444341256.ch13  0.56
2010 Zibaee S, Fraser G, Jakes R, Owen D, Serpell LC, Crowther RA, Goedert M. Human beta-synuclein rendered fibrillogenic by designed mutations. The Journal of Biological Chemistry. 285: 38555-67. PMID 20833719 DOI: 10.1074/jbc.M110.160721  0.56
2010 Hampton DW, Webber DJ, Bilican B, Goedert M, Spillantini MG, Chandran S. Cell-mediated neuroprotection in a mouse model of human tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9973-83. PMID 20668182 DOI: 10.1523/JNEUROSCI.0834-10.2010  0.56
2010 Garcia-Reitböck P, Anichtchik O, Bellucci A, Iovino M, Ballini C, Fineberg E, Ghetti B, Della Corte L, Spano P, Tofaris GK, Goedert M, Spillantini MG. SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease. Brain : a Journal of Neurology. 133: 2032-44. PMID 20534649 DOI: 10.1093/brain/awq132  0.56
2010 Goedert M, Clavaguera F, Tolnay M. The propagation of prion-like protein inclusions in neurodegenerative diseases. Trends in Neurosciences. 33: 317-25. PMID 20493564 DOI: 10.1016/j.tins.2010.04.003  0.56
2010 Clavaguera F, Goedert M, Tolnay M. [Induction and spreading of tau pathology in a mouse model of Alzheimer's disease]. MéDecine Sciences : M/S. 26: 121-4. PMID 20188034 DOI: 10.1051/medsci/2010262121  0.56
2010 Chambraud B, Sardin E, Giustiniani J, Dounane O, Schumacher M, Goedert M, Baulieu EE. A role for FKBP52 in Tau protein function. Proceedings of the National Academy of Sciences of the United States of America. 107: 2658-63. PMID 20133804 DOI: 10.1073/pnas.0914957107  0.56
2010 Scattoni ML, Gasparini L, Alleva E, Goedert M, Calamandrei G, Spillantini MG. Early behavioural markers of disease in P301S tau transgenic mice. Behavioural Brain Research. 208: 250-7. PMID 20004218 DOI: 10.1016/j.bbr.2009.12.002  0.56
2010 Goedert M. Parkinson's disease: Alpha-synuclein and neurodegeneration Encyclopedia of Neuroscience. 461-467. DOI: 10.1016/B978-008045046-9.00512-X  0.56
2009 Yamashita M, Nonaka T, Arai T, Kametani F, Buchman VL, Ninkina N, Bachurin SO, Akiyama H, Goedert M, Hasegawa M. Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models. Febs Letters. 583: 2419-24. PMID 19560462 DOI: 10.1016/j.febslet.2009.06.042  0.56
2009 Clavaguera F, Bolmont T, Crowther RA, Abramowski D, Frank S, Probst A, Fraser G, Stalder AK, Beibel M, Staufenbiel M, Jucker M, Goedert M, Tolnay M. Transmission and spreading of tauopathy in transgenic mouse brain. Nature Cell Biology. 11: 909-13. PMID 19503072 DOI: 10.1038/ncb1901  0.56
2009 Masuda M, Hasegawa M, Nonaka T, Oikawa T, Yonetani M, Yamaguchi Y, Kato K, Hisanaga S, Goedert M. Inhibition of alpha-synuclein fibril assembly by small molecules: analysis using epitope-specific antibodies. Febs Letters. 583: 787-91. PMID 19183551 DOI: 10.1016/j.febslet.2009.01.037  0.56
2009 Goedert M. Oskar Fischer and the study of dementia. Brain : a Journal of Neurology. 132: 1102-11. PMID 18952676 DOI: 10.1093/brain/awn256  0.56
2008 Kovacs GG, Majtenyi K, Spina S, Murrell JR, Gelpi E, Hoftberger R, Fraser G, Crowther RA, Goedert M, Budka H, Ghetti B. White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration. Journal of Neuropathology and Experimental Neurology. 67: 963-75. PMID 18800011 DOI: 10.1097/NEN.0b013e318187a80f  0.56
2008 Velasco A, Fraser G, Delobel P, Ghetti B, Lavenir I, Goedert M. Detection of filamentous tau inclusions by the fluorescent Congo red derivative FSB [(trans,trans)-1-fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene]. Febs Letters. 582: 901-6. PMID 18291106 DOI: 10.1016/j.febslet.2008.02.025  0.56
2008 Radde R, Duma C, Goedert M, Jucker M. The value of incomplete mouse models of Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging. 35: S70-4. PMID 18270700 DOI: 10.1007/s00259-007-0704-y  0.56
2008 Ye L, Velasco A, Fraser G, Beach TG, Sue L, Osredkar T, Libri V, Spillantini MG, Goedert M, Lockhart A. In vitro high affinity alpha-synuclein binding sites for the amyloid imaging agent PIB are not matched by binding to Lewy bodies in postmortem human brain. Journal of Neurochemistry. 105: 1428-37. PMID 18221373 DOI: 10.1111/j.1471-4159.2008.05245.x  0.56
2008 Delobel P, Lavenir I, Fraser G, Ingram E, Holzer M, Ghetti B, Spillantini MG, Crowther RA, Goedert M. Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy. The American Journal of Pathology. 172: 123-31. PMID 18079436 DOI: 10.2353/ajpath.2008.070627  0.56
2008 Spina S, Farlow MR, Unverzagt FW, Kareken DA, Murrell JR, Fraser G, Epperson F, Crowther RA, Spillantini MG, Goedert M, Ghetti B. The tauopathy associated with mutation +3 in intron 10 of Tau: characterization of the MSTD family. Brain : a Journal of Neurology. 131: 72-89. PMID 18065436 DOI: 10.1093/brain/awm280  0.56
2007 Zibaee S, Jakes R, Fraser G, Serpell LC, Crowther RA, Goedert M. Sequence Determinants for Amyloid Fibrillogenesis of Human alpha-Synuclein. Journal of Molecular Biology. 374: 454-64. PMID 17936783 DOI: 10.1016/j.jmb.2007.09.039  0.56
2007 Magnani E, Fan J, Gasparini L, Golding M, Williams M, Schiavo G, Goedert M, Amos LA, Spillantini MG. Interaction of tau protein with the dynactin complex. The Embo Journal. 26: 4546-54. PMID 17932487 DOI: 10.1038/sj.emboj.7601878  0.56
2007 Ishii A, Nonaka T, Taniguchi S, Saito T, Arai T, Mann D, Iwatsubo T, Hisanaga S, Goedert M, Hasegawa M. Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha-synuclein: Implication for alpha-synucleinopathies. Febs Letters. 581: 4711-7. PMID 17868672 DOI: 10.1016/j.febslet.2007.08.067  0.56
2007 Virdee K, Yoshida H, Peak-Chew S, Goedert M. Phosphorylation of human microtubule-associated protein tau by protein kinases of the AGC subfamily. Febs Letters. 581: 2657-62. PMID 17512525 DOI: 10.1016/j.febslet.2007.05.009  0.56
2007 Goedert M, Ghetti B. Alois Alzheimer: his life and times. Brain Pathology (Zurich, Switzerland). 17: 57-62. PMID 17493039 DOI: 10.1111/j.1750-3639.2007.00056.x  0.56
2007 Zibaee S, Makin OS, Goedert M, Serpell LC. A simple algorithm locates beta-strands in the amyloid fibril core of alpha-synuclein, Abeta, and tau using the amino acid sequence alone. Protein Science : a Publication of the Protein Society. 16: 906-18. PMID 17456743 DOI: 10.1110/ps.062624507  0.56
2007 Spina S, Murrell JR, Yoshida H, Ghetti B, Bermingham N, Sweeney B, Dlouhy SR, Crowther RA, Goedert M, Keohane C. The novel Tau mutation G335S: clinical, neuropathological and molecular characterization. Acta Neuropathologica. 113: 461-70. PMID 17186252 DOI: 10.1007/s00401-006-0182-5  0.56
2007 Ghetti B, Goedert M. Symposium: Tau protein and neurodegeneration Brain Pathology. 17: 56. DOI: 10.1111/j.1750-3639.2007.00057.x  0.56
2007 Goedert M, Spillantini MG. Chapter 4 Tau Protein and the Dementias Blue Books of Neurology. 30: 88-111. DOI: 10.1016/S1877-184X(09)70055-3  0.56
2006 Broersen K, van den Brink D, Fraser G, Goedert M, Davletov B. Alpha-synuclein adopts an alpha-helical conformation in the presence of polyunsaturated fatty acids to hinder micelle formation. Biochemistry. 45: 15610-6. PMID 17176082 DOI: 10.1021/bi061743l  0.56
2006 Goedert M, Spillantini MG. A century of Alzheimer's disease. Science (New York, N.Y.). 314: 777-81. PMID 17082447 DOI: 10.1126/science.1132814  0.56
2006 Goedert M, Spillantini MG. Frontotemporal lobar degeneration through loss of progranulin function. Brain : a Journal of Neurology. 129: 2808-10. PMID 17071919 DOI: 10.1093/brain/awl291  0.56
2006 Yoshida H, Goedert M. Sequential phosphorylation of tau protein by cAMP-dependent protein kinase and SAPK4/p38delta or JNK2 in the presence of heparin generates the AT100 epitope. Journal of Neurochemistry. 99: 154-64. PMID 16987243 DOI: 10.1111/j.1471-4159.2006.04052.x  0.56
2006 Spillantini MG, Murrell JR, Goedert M, Farlow M, Klug A, Ghetti B. Mutations in the tau gene (MAPT) in FTDP-17: the family with Multiple System Tauopathy with Presenile Dementia (MSTD). Journal of Alzheimer's Disease : Jad. 9: 373-80. PMID 16914875  0.56
2006 Goedert M, Klug A, Crowther RA. Tau protein, the paired helical filament and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 9: 195-207. PMID 16914859  0.56
2006 Masuda M, Suzuki N, Taniguchi S, Oikawa T, Nonaka T, Iwatsubo T, Hisanaga S, Goedert M, Hasegawa M. Small molecule inhibitors of alpha-synuclein filament assembly. Biochemistry. 45: 6085-94. PMID 16681381 DOI: 10.1021/bi0600749  0.56
2006 Tofaris GK, Garcia Reitböck P, Humby T, Lambourne SL, O'Connell M, Ghetti B, Gossage H, Emson PC, Wilkinson LS, Goedert M, Spillantini MG. Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3942-50. PMID 16611810 DOI: 10.1523/JNEUROSCI.4965-05.2006  0.56
2006 Masuda M, Dohmae N, Nonaka T, Oikawa T, Hisanaga S, Goedert M, Hasegawa M. Cysteine misincorporation in bacterially expressed human alpha-synuclein. Febs Letters. 580: 1775-9. PMID 16513114 DOI: 10.1016/j.febslet.2006.02.032  0.56
2006 Delobel P, Lavenir I, Ghetti B, Holzer M, Goedert M. Cell-cycle markers in a transgenic mouse model of human tauopathy: increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1. The American Journal of Pathology. 168: 878-87. PMID 16507903 DOI: 10.2353/ajpath.2006.050540  0.56
2006 Yoshida H, Craxton M, Jakes R, Zibaee S, Tavaré R, Fraser G, Serpell LC, Davletov B, Crowther RA, Goedert M. Synuclein proteins of the pufferfish Fugu rubripes: sequences and functional characterization. Biochemistry. 45: 2599-607. PMID 16489753 DOI: 10.1021/bi051993m  0.56
2005 Goedert M. Tau gene mutations and their effects. Movement Disorders : Official Journal of the Movement Disorder Society. 20: S45-52. PMID 16092090 DOI: 10.1002/mds.20539  0.56
2005 Yamaguchi K, Cochran EJ, Murrell JR, Polymeropoulos MH, Shannon KM, Crowther RA, Goedert M, Ghetti B. Abundant neuritic inclusions and microvacuolar changes in a case of diffuse Lewy body disease with the A53T mutation in the alpha-synuclein gene. Acta Neuropathologica. 110: 298-305. PMID 15981014 DOI: 10.1007/s00401-005-1042-4  0.56
2005 Sabio G, Arthur JS, Kuma Y, Peggie M, Carr J, Murray-Tait V, Centeno F, Goedert M, Morrice NA, Cuenda A. p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP. The Embo Journal. 24: 1134-45. PMID 15729360 DOI: 10.1038/sj.emboj.7600578  0.56
2005 Feijoo C, Campbell DG, Jakes R, Goedert M, Cuenda A. Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38delta at Thr50 promotes microtubule assembly. Journal of Cell Science. 118: 397-408. PMID 15632108 DOI: 10.1242/jcs.01655  0.56
2005 Goedert M, Jakes R. Mutations causing neurodegenerative tauopathies. Biochimica Et Biophysica Acta. 1739: 240-50. PMID 15615642 DOI: 10.1016/j.bbadis.2004.08.007  0.56
2005 Taniguchi S, Suzuki N, Masuda M, Hisanaga S, Iwatsubo T, Goedert M, Hasegawa M. Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins. The Journal of Biological Chemistry. 280: 7614-23. PMID 15611092 DOI: 10.1074/jbc.M408714200  0.56
2004 Bellucci A, Westwood AJ, Ingram E, Casamenti F, Goedert M, Spillantini MG. Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein. The American Journal of Pathology. 165: 1643-52. PMID 15509534 DOI: 10.1016/S0002-9440(10)63421-9  0.56
2004 Choi W, Zibaee S, Jakes R, Serpell LC, Davletov B, Crowther RA, Goedert M. Mutation E46K increases phospholipid binding and assembly into filaments of human alpha-synuclein. Febs Letters. 576: 363-8. PMID 15498564 DOI: 10.1016/j.febslet.2004.09.038  0.56
2004 Holzer M, Craxton M, Jakes R, Arendt T, Goedert M. Tau gene (MAPT) sequence variation among primates. Gene. 341: 313-22. PMID 15474313 DOI: 10.1016/j.gene.2004.07.013  0.56
2004 Yoshida H, Hastie CJ, McLauchlan H, Cohen P, Goedert M. Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase (JNK). Journal of Neurochemistry. 90: 352-8. PMID 15228592 DOI: 10.1111/j.1471-4159.2004.02479.x  0.56
2004 Takao M, Ghetti B, Yoshida H, Piccardo P, Narain Y, Murrell JR, Vidal R, Glazier BS, Jakes R, Tsutsui M, Spillantini MG, Crowther RA, Goedert M, Koto A. Early-onset dementia with Lewy bodies. Brain Pathology (Zurich, Switzerland). 14: 137-47. PMID 15193026  0.56
2004 Cohen P, Goedert M. GSK3 inhibitors: development and therapeutic potential. Nature Reviews. Drug Discovery. 3: 479-87. PMID 15173837 DOI: 10.1038/nrd1415  0.56
2004 Goedert M. Tau protein and neurodegeneration. Seminars in Cell & Developmental Biology. 15: 45-9. PMID 15036206 DOI: 10.1016/j.semcdb.2003.12.015  0.56
2004 Sabio G, Reuver S, Feijoo C, Hasegawa M, Thomas GM, Centeno F, Kuhlendahl S, Leal-Ortiz S, Goedert M, Garner C, Cuenda A. Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2. The Biochemical Journal. 380: 19-30. PMID 14741046 DOI: 10.1042/BJ20031628  0.56
2004 Goedert M. α-Synuclein and Neurodegeneration Primer On the Autonomic Nervous System: Second Edition. 204-207. DOI: 10.1016/B978-012589762-4/50055-4  0.56
2003 van Herpen E, Rosso SM, Serverijnen LA, Yoshida H, Breedveld G, van de Graaf R, Kamphorst W, Ravid R, Willemsen R, Dooijes D, Majoor-Krakauer D, Kros JM, Crowther RA, Goedert M, Heutink P, et al. Variable phenotypic expression and extensive tau pathology in two families with the novel tau mutation L315R. Annals of Neurology. 54: 573-81. PMID 14595646 DOI: 10.1002/ana.10721  0.56
2003 Goedert M. Neurodegenerative tauopathy in the worm. Proceedings of the National Academy of Sciences of the United States of America. 100: 9653-5. PMID 12913116 DOI: 10.1073/pnas.1834191100  0.56
2003 Berriman J, Serpell LC, Oberg KA, Fink AL, Goedert M, Crowther RA. Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-beta structure. Proceedings of the National Academy of Sciences of the United States of America. 100: 9034-8. PMID 12853572 DOI: 10.1073/pnas.1530287100  0.56
2003 Kar S, Fan J, Smith MJ, Goedert M, Amos LA. Repeat motifs of tau bind to the insides of microtubules in the absence of taxol. The Embo Journal. 22: 70-7. PMID 12505985 DOI: 10.1093/emboj/cdg001  0.56
2002 Yoshida H, Goedert M. Molecular cloning and functional characterization of chicken brain tau: isoforms with up to five tandem repeats. Biochemistry. 41: 15203-11. PMID 12484758 DOI: 10.1021/bi026464m  0.56
2002 Allen B, Ingram E, Takao M, Smith MJ, Jakes R, Virdee K, Yoshida H, Holzer M, Craxton M, Emson PC, Atzori C, Migheli A, Crowther RA, Ghetti B, Spillantini MG, ... Goedert M, et al. Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9340-51. PMID 12417659  0.56
2002 David DC, Layfield R, Serpell L, Narain Y, Goedert M, Spillantini MG. Proteasomal degradation of tau protein. Journal of Neurochemistry. 83: 176-85. PMID 12358741 DOI: 10.1046/j.1471-4159.2002.01137.x  0.56
2002 Buée-Scherrer V, Goedert M. Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases in intact cells. Febs Letters. 515: 151-4. PMID 11943212 DOI: 10.1016/S0014-5793(02)02460-2  0.56
2002 Rosso SM, van Herpen E, Deelen W, Kamphorst W, Severijnen LA, Willemsen R, Ravid R, Niermeijer MF, Dooijes D, Smith MJ, Goedert M, Heutink P, van Swieten JC. A novel tau mutation, S320F, causes a tauopathy with inclusions similar to those in Pick's disease. Annals of Neurology. 51: 373-6. PMID 11891833 DOI: 10.1002/ana.10140  0.56
2002 Uversky VN, Li J, Souillac P, Millett IS, Doniach S, Jakes R, Goedert M, Fink AL. Biophysical properties of the synucleins and their propensities to fibrillate: inhibition of alpha-synuclein assembly by beta- and gamma-synucleins. The Journal of Biological Chemistry. 277: 11970-8. PMID 11812782 DOI: 10.1074/jbc.M109541200  0.56
2002 Syme CD, Blanch EW, Holt C, Jakes R, Goedert M, Hecht L, Barron LD. A Raman optical activity study of rheomorphism in caseins, synucleins and tau. New insight into the structure and behaviour of natively unfolded proteins. European Journal of Biochemistry / Febs. 269: 148-56. PMID 11784308 DOI: 10.1046/j.0014-2956.2001.02633.x  0.56
2002 Delobel P, Flament S, Hamdane M, Jakes R, Rousseau A, Delacourte A, Vilain JP, Goedert M, Buée L. Functional characterization of FTDP-17 tau gene mutations through their effects on Xenopus oocyte maturation. The Journal of Biological Chemistry. 277: 9199-205. PMID 11756436 DOI: 10.1074/jbc.M107716200  0.56
2001 Spillantini MG, Goedert M. Tau and Parkinson disease. Jama. 286: 2324-6. PMID 11710900  0.56
2001 Neumann M, Schulz-Schaeffer W, Crowther RA, Smith MJ, Spillantini MG, Goedert M, Kretzschmar HA. Pick's disease associated with the novel Tau gene mutation K369I. Annals of Neurology. 50: 503-13. PMID 11601501 DOI: 10.1002/ana.1223  0.56
2001 Lee VM, Goedert M, Trojanowski JQ. Neurodegenerative tauopathies. Annual Review of Neuroscience. 24: 1121-59. PMID 11520930 DOI: 10.1146/annurev.neuro.24.1.1121  0.56
2001 Hartmann AM, Rujescu D, Giannakouros T, Nikolakaki E, Goedert M, Mandelkow EM, Gao QS, Andreadis A, Stamm S. Regulation of alternative splicing of human tau exon 10 by phosphorylation of splicing factors. Molecular and Cellular Neurosciences. 18: 80-90. PMID 11461155 DOI: 10.1006/mcne.2001.1000  0.56
2001 Goedert M, Spillantini MG. Tau gene mutations and neurodegeneration. Biochemical Society Symposium. 59-71. PMID 11447840  0.56
2001 Goedert M. Alpha-synuclein and neurodegenerative diseases. Nature Reviews. Neuroscience. 2: 492-501. PMID 11433374 DOI: 10.1038/35081564  0.56
2001 Götz J, Tolnay M, Barmettler R, Ferrari A, Bürki K, Goedert M, Probst A, Nitsch RM. Human tau transgenic mice. Towards an animal model for neuro- and glialfibrillary lesion formation. Advances in Experimental Medicine and Biology. 487: 71-83. PMID 11403167  0.56
2001 Spillantini MG, Goedert M. Tau gene mutations and tau pathology in frontotemporal dementia and parkinsonism linked to chromosome 17. Advances in Experimental Medicine and Biology. 487: 21-37. PMID 11403160  0.56
2001 Goedert M. Parkinson's disease and other alpha-synucleinopathies. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 39: 308-12. PMID 11388653 DOI: 10.1515/CCLM.2001.047  0.56
2001 Goedert M. The significance of tau and alpha-synuclein inclusions in neurodegenerative diseases. Current Opinion in Genetics & Development. 11: 343-51. PMID 11377973 DOI: 10.1016/S0959-437X(00)00200-8  0.56
2001 Woods YL, Cohen P, Becker W, Jakes R, Goedert M, Wang X, Proud CG. The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase. The Biochemical Journal. 355: 609-15. PMID 11311121  0.56
2001 Goedert M, Spillantini MG, Serpell LC, Berriman J, Smith MJ, Jakes R, Crowther RA. From genetics to pathology: tau and alpha-synuclein assemblies in neurodegenerative diseases. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 356: 213-27. PMID 11260802 DOI: 10.1098/rstb.2000.0767  0.56
2000 Goedert M, Ghetti B, Spillantini MG. Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Their relevance for understanding the neurogenerative process. Annals of the New York Academy of Sciences. 920: 74-83. PMID 11193179  0.56
2000 Ghetti B, Murrell JR, Zolo P, Spillantini MG, Goedert M. Progress in hereditary tauopathies: a mutation in the Tau gene (G389R) causes a Pick disease-like syndrome. Annals of the New York Academy of Sciences. 920: 52-62. PMID 11193177  0.56
2000 Spillantini MG, Goedert M. The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Annals of the New York Academy of Sciences. 920: 16-27. PMID 11193145  0.56
2000 Götz J, Barmettler R, Ferrari A, Goedert M, Probst A, Nitsch RM. In vivo analysis of wild-type and FTDP-17 tau transgenic mice. Annals of the New York Academy of Sciences. 920: 126-33. PMID 11193141  0.56
2000 Spillantini MG, Yoshida H, Rizzini C, Lantos PL, Khan N, Rossor MN, Goedert M, Brown J. A novel tau mutation (N296N) in familial dementia with swollen achromatic neurons and corticobasal inclusion bodies. Annals of Neurology. 48: 939-43. PMID 11117553 DOI: 10.1002/1531-8249(200012)48:6<939::AID-ANA17>3.0.CO;2-1  0.56
2000 Rizzini C, Goedert M, Hodges JR, Smith MJ, Jakes R, Hills R, Xuereb JH, Crowther RA, Spillantini MG. Tau gene mutation K257T causes a tauopathy similar to Pick's disease. Journal of Neuropathology and Experimental Neurology. 59: 990-1001. PMID 11089577  0.56
2000 Smith MJ, Crowther RA, Goedert M. The natural osmolyte trimethylamine N-oxide (TMAO) restores the ability of mutant tau to promote microtubule assembly. Febs Letters. 484: 265-70. PMID 11078890 DOI: 10.1016/S0014-5793(00)02169-4  0.56
2000 Fleming Y, Armstrong CG, Morrice N, Paterson A, Goedert M, Cohen P. Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7. The Biochemical Journal. 352: 145-54. PMID 11062067 DOI: 10.1042/0264-6021:3520145  0.56
2000 Goedert M, Satumtira S, Jakes R, Smith MJ, Kamibayashi C, White CL, Sontag E. Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations. Journal of Neurochemistry. 75: 2155-62. PMID 11032905 DOI: 10.1046/j.1471-4159.2000.0752155.x  0.56
2000 Crowther RA, Daniel SE, Goedert M. Characterisation of isolated alpha-synuclein filaments from substantia nigra of Parkinson's disease brain. Neuroscience Letters. 292: 128-30. PMID 10998565 DOI: 10.1016/S0304-3940(00)01440-3  0.56
2000 Spillantini MG, Van Swieten JC, Goedert M. Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Neurogenetics. 2: 193-205. PMID 10983715  0.56
2000 Crowther RA, Goedert M. Abnormal tau-containing filaments in neurodegenerative diseases. Journal of Structural Biology. 130: 271-9. PMID 10940231 DOI: 10.1006/jsbi.2000.4270  0.56
2000 Goedert M, Spillantini MG. Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease. Biochimica Et Biophysica Acta. 1502: 110-21. PMID 10899436 DOI: 10.1016/S0925-4439(00)00037-5  0.56
2000 Probst A, Götz J, Wiederhold KH, Tolnay M, Mistl C, Jaton AL, Hong M, Ishihara T, Lee VM, Trojanowski JQ, Jakes R, Crowther RA, Spillantini MG, Bürki K, Goedert M. Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein. Acta Neuropathologica. 99: 469-81. PMID 10805089  0.56
2000 Duff K, Knight H, Refolo LM, Sanders S, Yu X, Picciano M, Malester B, Hutton M, Adamson J, Goedert M, Burki K, Davies P. Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes. Neurobiology of Disease. 7: 87-98. PMID 10783293 DOI: 10.1006/nbdi.1999.0279  0.56
2000 Serpell LC, Berriman J, Jakes R, Goedert M, Crowther RA. Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation. Proceedings of the National Academy of Sciences of the United States of America. 97: 4897-902. PMID 10781096 DOI: 10.1073/pnas.97.9.4897  0.56
2000 Spillantini MG, Goedert M. Tau mutations in familial frontotemporal dementia. Brain : a Journal of Neurology. 123: 857-9. PMID 10775532  0.56
2000 Yasuda M, Takamatsu J, D'Souza I, Crowther RA, Kawamata T, Hasegawa M, Hasegawa H, Spillantini MG, Tanimukai S, Poorkaj P, Varani L, Varani G, Iwatsubo T, Goedert M, Schellenberg DG, et al. A novel mutation at position +12 in the intron following exon 10 of the tau gene in familial frontotemporal dementia (FTD-Kumamoto) Annals of Neurology. 47: 422-9. PMID 10762152 DOI: 10.1002/1531-8249(200004)47:4<422::AID-ANA4>3.0.CO;2-G  0.56
2000 Giasson BI, Jakes R, Goedert M, Duda JE, Leight S, Trojanowski JQ, Lee VM. A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease. Journal of Neuroscience Research. 59: 528-33. PMID 10679792 DOI: 10.1002/(SICI)1097-4547(20000215)59:4<528::AID-JNR8>3.0.CO;2-0  0.56
2000 Varani L, Spillantini MG, Goedert M, Varani G. Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics. Nucleic Acids Research. 28: 710-9. PMID 10637322  0.56
1999 Jakes R, Crowther RA, Lee VM, Trojanowski JQ, Iwatsubo T, Goedert M. Epitope mapping of LB509, a monoclonal antibody directed against human alpha-synuclein. Neuroscience Letters. 269: 13-6. PMID 10821633 DOI: 10.1016/S0304-3940(99)00411-5  0.56
1999 Goedert M, Klug A. Tau protein and the paired helical filament of Alzheimer's disease. Brain Research Bulletin. 50: 469-70. PMID 10643488 DOI: 10.1016/S0361-9230(99)00138-0  0.56
1999 Murrell JR, Spillantini MG, Zolo P, Guazzelli M, Smith MJ, Hasegawa M, Redi F, Crowther RA, Pietrini P, Ghetti B, Goedert M. Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits. Journal of Neuropathology and Experimental Neurology. 58: 1207-26. PMID 10604746  0.56
1999 Craxton M, Goedert M. Alternative splicing of synaptotagmins involving transmembrane exon skipping. Febs Letters. 460: 417-22. PMID 10556508 DOI: 10.1016/S0014-5793(99)01382-4  0.56
1999 Börsch-Haubold AG, Ghomashchi F, Pasquet S, Goedert M, Cohen P, Gelb MH, Watson SP. Phosphorylation of cytosolic phospholipase A2 in platelets is mediated by multiple stress-activated protein kinase pathways. European Journal of Biochemistry / Febs. 265: 195-203. PMID 10491174 DOI: 10.1046/j.1432-1327.1999.00722.x  0.56
1999 Thomas GM, Frame S, Goedert M, Nathke I, Polakis P, Cohen P. A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin. Febs Letters. 458: 247-51. PMID 10481074 DOI: 10.1016/S0014-5793(99)01161-8  0.56
1999 Goedert M. Filamentous nerve cell inclusions in neurodegenerative diseases: tauopathies and alpha-synucleinopathies. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 354: 1101-18. PMID 10434313 DOI: 10.1098/rstb.1999.0466  0.56
1999 Hall-Jackson CA, Eyers PA, Cohen P, Goedert M, Boyle FT, Hewitt N, Plant H, Hedge P. Paradoxical activation of Raf by a novel Raf inhibitor. Chemistry & Biology. 6: 559-68. PMID 10421767 DOI: 10.1016/S1074-5521(99)80088-X  0.56
1999 Varani L, Hasegawa M, Spillantini MG, Smith MJ, Murrell JR, Ghetti B, Klug A, Goedert M, Varani G. Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17. Proceedings of the National Academy of Sciences of the United States of America. 96: 8229-34. PMID 10393977 DOI: 10.1073/pnas.96.14.8229  0.56
1999 Goedert M. Alzheimer's disease. Pinning down phosphorylated tau. Nature. 399: 739-40. PMID 10391237 DOI: 10.1038/21550  0.56
1999 Spillantini MG, Tolnay M, Love S, Goedert M. Microtubule-associated protein tau, heparan sulphate and alpha-synuclein in several neurodegenerative diseases with dementia. Acta Neuropathologica. 97: 585-94. PMID 10378377 DOI: 10.1007/s004010051034  0.56
1999 Bugiani O, Murrell JR, Giaccone G, Hasegawa M, Ghigo G, Tabaton M, Morbin M, Primavera A, Carella F, Solaro C, Grisoli M, Savoiardo M, Spillantini MG, Tagliavini F, Goedert M, et al. Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau. Journal of Neuropathology and Experimental Neurology. 58: 667-77. PMID 10374757  0.56
1999 Eyers PA, van den IJssel P, Quinlan RA, Goedert M, Cohen P. Use of a drug-resistant mutant of stress-activated protein kinase 2a/p38 to validate the in vivo specificity of SB 203580. Febs Letters. 451: 191-6. PMID 10371163 DOI: 10.1016/S0014-5793(99)00552-9  0.56
1999 Goedert M, Jakes R, Crowther RA. Effects of frontotemporal dementia FTDP-17 mutations on heparin-induced assembly of tau filaments. Febs Letters. 450: 306-11. PMID 10359094 DOI: 10.1016/S0014-5793(99)00508-6  0.56
1999 Hall-Jackson CA, Goedert M, Hedge P, Cohen P. Effect of SB 203580 on the activity of c-Raf in vitro and in vivo. Oncogene. 18: 2047-54. PMID 10321729 DOI: 10.1038/sj.onc.1202603  0.56
1999 Mirra SS, Murrell JR, Gearing M, Spillantini MG, Goedert M, Crowther RA, Levey AI, Jones R, Green J, Shoffner JM, Wainer BH, Schmidt ML, Trojanowski JQ, Ghetti B. Tau pathology in a family with dementia and a P301L mutation in tau. Journal of Neuropathology and Experimental Neurology. 58: 335-45. PMID 10218629  0.56
1999 Hasegawa M, Cuenda A, Spillantini MG, Thomas GM, Buée-Scherrer V, Cohen P, Goedert M. Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition. The Journal of Biological Chemistry. 274: 12626-31. PMID 10212242 DOI: 10.1074/jbc.274.18.12626  0.56
1999 Goedert M, Spillantini MG, Crowther RA, Chen SG, Parchi P, Tabaton M, Lanska DJ, Markesbery WR, Wilhelmsen KC, Dickson DW, Petersen RB, Gambetti P. Tau gene mutation in familial progressive subcortical gliosis. Nature Medicine. 5: 454-7. PMID 10202939 DOI: 10.1038/7454  0.56
1999 Hasegawa M, Smith MJ, Iijima M, Tabira T, Goedert M. FTDP-17 mutations N279K and S305N in tau produce increased splicing of exon 10. Febs Letters. 443: 93-6. PMID 9989582 DOI: 10.1016/S0014-5793(98)01696-2  0.56
1999 Rizzu P, Van Swieten JC, Joosse M, Hasegawa M, Stevens M, Tibben A, Niermeijer MF, Hillebrand M, Ravid R, Oostra BA, Goedert M, van Duijn CM, Heutink P. High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands. American Journal of Human Genetics. 64: 414-21. PMID 9973279 DOI: 10.1086/302256  0.56
1999 Goedert M, Hasegawa M. The tauopathies: toward an experimental animal model. The American Journal of Pathology. 154: 1-6. PMID 9916910 DOI: 10.1016/S0002-9440(10)65242-X  0.56
1998 Goedert M. Neurofibrillary pathology of Alzheimer's disease and other tauopathies. Progress in Brain Research. 117: 287-306. PMID 9932415  0.56
1998 Lawler S, Fleming Y, Goedert M, Cohen P. Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro. Current Biology : Cb. 8: 1387-90. PMID 9889102  0.56
1998 Goedert M, Spillantini MG. Lewy body diseases and multiple system atrophy as alpha-synucleinopathies. Molecular Psychiatry. 3: 462-5. PMID 9857966  0.56
1998 Goedert M, Crowther RA, Spillantini MG. Tau mutations cause frontotemporal dementias. Neuron. 21: 955-8. PMID 9856453 DOI: 10.1016/S0896-6273(00)80615-7  0.56
1998 Hasegawa M, Smith MJ, Goedert M. Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly. Febs Letters. 437: 207-10. PMID 9824291 DOI: 10.1016/S0014-5793(98)01217-4  0.56
1998 Goedert M, Spillantini MG, Davies SW. Filamentous nerve cell inclusions in neurodegenerative diseases. Current Opinion in Neurobiology. 8: 619-32. PMID 9811617 DOI: 10.1016/S0959-4388(98)80090-1  0.56
1998 Crowther RA, Jakes R, Spillantini MG, Goedert M. Synthetic filaments assembled from C-terminally truncated alpha-synuclein. Febs Letters. 436: 309-12. PMID 9801138 DOI: 10.1016/S0014-5793(98)01146-6  0.56
1998 Spillantini MG, Goedert M. Tau protein pathology in neurodegenerative diseases. Trends in Neurosciences. 21: 428-33. PMID 9786340 DOI: 10.1016/S0166-2236(98)01337-X  0.56
1998 Goedert M, Jakes R, Crowther RA, Hasegawa M, Smith MJ, Spillantini MG. Intraneuronal filamentous tau protein and alpha-synuclein deposits in neurodegenerative diseases. Biochemical Society Transactions. 26: 463-71. PMID 9765897  0.56
1998 Jensen PH, Nielsen MS, Jakes R, Dotti CG, Goedert M. Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation. The Journal of Biological Chemistry. 273: 26292-4. PMID 9756856 DOI: 10.1074/jbc.273.41.26292  0.56
1998 Spillantini MG, Murrell JR, Goedert M, Farlow MR, Klug A, Ghetti B. Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proceedings of the National Academy of Sciences of the United States of America. 95: 7737-41. PMID 9636220 DOI: 10.1073/pnas.95.13.7737  0.56
1998 Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M. alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proceedings of the National Academy of Sciences of the United States of America. 95: 6469-73. PMID 9600990 DOI: 10.1073/pnas.95.11.6469  0.56
1997 Murrell JR, Koller D, Foroud T, Goedert M, Spillantini MG, Edenberg HJ, Farlow MR, Ghetti B. Familial multiple-system tauopathy with presenile dementia is localized to chromosome 17. American Journal of Human Genetics. 61: 1131-8. PMID 9345089 DOI: 10.1086/301594  0.56
1997 Lawler S, Cuenda A, Goedert M, Cohen P. SKK4, a novel activator of stress-activated protein kinase-1 (SAPK1/JNK). Febs Letters. 414: 153-8. PMID 9305750 DOI: 10.1016/S0014-5793(97)00990-3  0.56
1997 Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M. Alpha-synuclein in Lewy bodies. Nature. 388: 839-40. PMID 9278044 DOI: 10.1038/42166  0.56
1997 Sergeant N, David JP, Goedert M, Jakes R, Vermersch P, Buée L, Lefranc D, Wattez A, Delacourte A. Two-dimensional characterization of paired helical filament-tau from Alzheimer's disease: demonstration of an additional 74-kDa component and age-related biochemical modifications. Journal of Neurochemistry. 69: 834-44. PMID 9231745  0.56
1997 Chevallier N, Jiracek J, Vincent B, Baur CP, Spillantini MG, Goedert M, Dive V, Checler F. Examination of the role of endopeptidase 3.4.24.15 in A beta secretion by human transfected cells. British Journal of Pharmacology. 121: 556-62. PMID 9179400 DOI: 10.1038/sj.bjp.0701151  0.56
1997 Tolnay M, Spillantini MG, Goedert M, Ulrich J, Langui D, Probst A. Argyrophilic grain disease: widespread hyperphosphorylation of tau protein in limbic neurons. Acta Neuropathologica. 93: 477-84. PMID 9144586 DOI: 10.1007/s004010050642  0.56
1997 Spillantini MG, Goedert M, Crowther RA, Murrell JR, Farlow MR, Ghetti B. Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments. Proceedings of the National Academy of Sciences of the United States of America. 94: 4113-8. PMID 9108114 DOI: 10.1073/pnas.94.8.4113  0.56
1996 Goedert M, Spillantini MG, Hasegawa M, Jakes R, Crowther RA, Klug A. Molecular dissection of the neurofibrillary lesions of Alzheimer's disease. Cold Spring Harbor Symposia On Quantitative Biology. 61: 565-73. PMID 9246483  0.56
1996 Probst A, Tolnay M, Langui D, Goedert M, Spillantini MG. Pick's disease: hyperphosphorylated tau protein segregates to the somatoaxonal compartment. Acta Neuropathologica. 92: 588-96. PMID 8960316 DOI: 10.1007/s004010050565  0.56
1996 Goedert M, Baur CP, Ahringer J, Jakes R, Hasegawa M, Spillantini MG, Smith MJ, Hill F. PTL-1, a microtubule-associated protein with tau-like repeats from the nematode Caenorhabditis elegans. Journal of Cell Science. 109: 2661-72. PMID 8937984  0.56
1996 Goedert M, Jakes R, Spillantini MG, Hasegawa M, Smith MJ, Crowther RA. Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans. Nature. 383: 550-3. PMID 8849730 DOI: 10.1038/383550a0  0.56
1996 Spillantini MG, Crowther RA, Goedert M. Comparison of the neurofibrillary pathology in Alzheimer's disease and familial presenile dementia with tangles. Acta Neuropathologica. 92: 42-8. PMID 8811124 DOI: 10.1007/s004010050487  0.56
1996 Buée-Scherrer V, Condamines O, Mourton-Gilles C, Jakes R, Goedert M, Pau B, Delacourte A. AD2, a phosphorylation-dependent monoclonal antibody directed against tau proteins found in Alzheimer's disease. Brain Research. Molecular Brain Research. 39: 79-88. PMID 8804716 DOI: 10.1016/0169-328X(96)00003-4  0.56
1996 Litersky JM, Johnson GV, Jakes R, Goedert M, Lee M, Seubert P. Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-356. The Biochemical Journal. 316: 655-60. PMID 8687413  0.56
1996 Roses AD, Einstein G, Gilbert J, Goedert M, Han SH, Huang D, Hulette C, Masliah E, Pericak-Vance MA, Saunders AM, Schmechel DE, Strittmatter WJ, Weisgraber KH, Xi PT. Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism. Annals of the New York Academy of Sciences. 777: 146-57. PMID 8624078  0.56
1996 Ghetti B, Piccardo P, Spillantini MG, Ichimiya Y, Porro M, Perini F, Kitamoto T, Tateishi J, Seiler C, Frangione B, Bugiani O, Giaccone G, Prelli F, Goedert M, Dlouhy SR, et al. Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP. Proceedings of the National Academy of Sciences of the United States of America. 93: 744-8. PMID 8570627 DOI: 10.1073/pnas.93.2.744  0.56
1995 Goedert M, Jakes R, Spillantini MG, Crowther RA, Cohen P, Vanmechelen E, Probst A, Götz J, Bürki K. Tau protein in Alzheimer's disease. Biochemical Society Transactions. 23: 80-5. PMID 7758799  0.56
1995 Götz J, Probst A, Spillantini MG, Schäfer T, Jakes R, Bürki K, Goedert M. Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform. The Embo Journal. 14: 1304-13. PMID 7729409  0.56
1995 Seubert P, Mawal-Dewan M, Barbour R, Jakes R, Goedert M, Johnson GV, Litersky JM, Schenk D, Lieberburg I, Trojanowski JQ. Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau. The Journal of Biological Chemistry. 270: 18917-22. PMID 7642549  0.56
1995 Jakes R, Harrington CR, Spillantini MG, Goedert M, Klug A. Characterisation of an antibody relevant to the neuropathology of Alzheimer disease. Alzheimer Disease and Associated Disorders. 9: 47-51. PMID 7605621  0.56
1995 Huang DY, Weisgraber KH, Goedert M, Saunders AM, Roses AD, Strittmatter WJ. ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylation. Neuroscience Letters. 192: 209-12. PMID 7566652 DOI: 10.1016/0304-3940(95)11649-H  0.56
1995 Goedert M, Spillantini MG, Jakes R, Crowther RA, Vanmechelen E, Probst A, Götz J, Bürki K, Cohen P. Molecular dissection of the paired helical filament. Neurobiology of Aging. 16: 325-34. PMID 7566342 DOI: 10.1016/0197-4580(95)00017-9  0.56
1995 Spillantini MG, Divane A, Goedert M. Assignment of human alpha-synuclein (SNCA) and beta-synuclein (SNCB) genes to chromosomes 4q21 and 5q35. Genomics. 27: 379-81. PMID 7558013 DOI: 10.1006/geno.1995.1063  0.56
1994 Strittmatter WJ, Weisgraber KH, Goedert M, Saunders AM, Huang D, Corder EH, Dong LM, Jakes R, Alberts MJ, Gilbert JR. Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype. Experimental Neurology. 125: 163-71; discussion 1. PMID 8313935 DOI: 10.1006/exnr.1994.1019  0.56
1994 Jakes R, Spillantini MG, Goedert M. Identification of two distinct synucleins from human brain. Febs Letters. 345: 27-32. PMID 8194594 DOI: 10.1016/0014-5793(94)00395-5  0.56
1994 Strittmatter WJ, Saunders AM, Goedert M, Weisgraber KH, Dong LM, Jakes R, Huang DY, Pericak-Vance M, Schmechel D, Roses AD. Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 91: 11183-6. PMID 7972031  0.56
1994 Goedert M, Strittmatter WJ, Roses AD. Alzheimer's disease. Risky apolipoprotein in brain. Nature. 372: 45-6. PMID 7969418 DOI: 10.1038/372045a0  0.56
1994 Huang DY, Goedert M, Jakes R, Weisgraber KH, Garner CC, Saunders AM, Pericak-Vance MA, Schmechel DE, Roses AD, Strittmatter WJ. Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease. Neuroscience Letters. 182: 55-8. PMID 7891887 DOI: 10.1016/0304-3940(94)90204-6  0.56
1994 Fawcett JW, Mathews G, Housden E, Goedert M, Matus A. Regenerating sciatic nerve axons contain the adult rather than the embryonic pattern of microtubule associated proteins. Neuroscience. 61: 789-804. PMID 7838378 DOI: 10.1016/0306-4522(94)90402-2  0.56
1994 Goedert M, Jakes R, Crowther RA, Cohen P, Vanmechelen E, Vandermeeren M, Cras P. Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein. The Biochemical Journal. 301: 871-7. PMID 7519852  0.56
1993 Goedert M, Jakes R, Crowther RA, Six J, Lübke U, Vandermeeren M, Cras P, Trojanowski JQ, Lee VM. The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development. Proceedings of the National Academy of Sciences of the United States of America. 90: 5066-70. PMID 8506352  0.56
1993 Lo MM, Fieles AW, Norris TE, Dargis PG, Caputo CB, Scott CW, Lee VM, Goedert M. Human tau isoforms confer distinct morphological and functional properties to stably transfected fibroblasts. Brain Research. Molecular Brain Research. 20: 209-20. PMID 8302159 DOI: 10.1016/0169-328X(93)90043-O  0.56
1993 Robertson J, Loviny TL, Goedert M, Jakes R, Murray KJ, Anderton BH, Hanger DP. Phosphorylation of tau by cyclic-AMP-dependent protein kinase. Dementia (Basel, Switzerland). 4: 256-63. PMID 8261023  0.56
1992 Goedert M, Spillantini MG, Crowther RA. Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system. Proceedings of the National Academy of Sciences of the United States of America. 89: 1983-7. PMID 1542696  0.56
1992 Goedert M, Spillantini MG, Cairns NJ, Crowther RA. Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms. Neuron. 8: 159-68. PMID 1530909 DOI: 10.1016/0896-6273(92)90117-V  0.56
1992 Potier MC, Kuo WL, Dutriaux A, Gray J, Goedert M. Construction and characterization of a yeast artificial chromosome library containing 1.5 equivalents of human chromosome 21. Genomics. 14: 481-3. PMID 1427862 DOI: 10.1016/S0888-7543(05)80245-9  0.56
1991 Goedert M, Spillantini MG, Jakes R. Localization of the Alz-50 epitope in recombinant human microtubule-associated protein tau. Neuroscience Letters. 126: 149-54. PMID 1717895 DOI: 10.1016/0304-3940(91)90541-Z  0.56
1991 Dingus J, Obar RA, Hyams JS, Goedert M, Vallee RB. Use of a heat-stable microtubule-associated protein class-specific antibody to investigate the mechanism of microtubule binding. The Journal of Biological Chemistry. 266: 18854-60. PMID 1717454  0.56
1991 Goedert M, Crowther RA, Garner CC. Molecular characterization of microtubule-associated proteins tau and MAP2. Trends in Neurosciences. 14: 193-9. PMID 1713721  0.56
1991 Goedert M, Spillantini MG, Crowther RA. Tau proteins and neurofibrillary degeneration. Brain Pathology (Zurich, Switzerland). 1: 279-86. PMID 1669718  0.56
1990 Hanley MR, Cheung WT, Hawkins P, Poyner D, Benton HP, Blair L, Jackson TR, Goedert M. The mas oncogene as a neural peptide receptor: expression, regulation and mechanism of action. Ciba Foundation Symposium. 150: 23-38; discussion 38. PMID 2197067  0.56
1990 Kindler S, Schulz B, Goedert M, Garner CC. Molecular structure of microtubule-associated protein 2b and 2c from rat brain. The Journal of Biological Chemistry. 265: 19679-84. PMID 2174050  0.56
1990 Spillantini MG, Goedert M, Jakes R, Klug A. Different configurational states of beta-amyloid and their distributions relative to plaques and tangles in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 87: 3947-51. PMID 2111023 DOI: 10.1073/pnas.87.10.3947  0.56
1990 Goedert M, Spillantini MG. Molecular neuropathology of Alzheimer's disease: in situ hybridization studies. Cellular and Molecular Neurobiology. 10: 159-74. PMID 2110505 DOI: 10.1007/BF00733642  0.56
1990 Spillantini MG, Goedert M, Jakes R, Klug A. Topographical relationship between beta-amyloid and tau protein epitopes in tangle-bearing cells in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 87: 3952-6. PMID 1692627 DOI: 10.1073/pnas.87.10.3952  0.56
1989 Spillantini MG, Aloe L, Alleva E, De Simone R, Goedert M, Levi-Montalcini R. Nerve growth factor mRNA and protein increase in hypothalamus in a mouse model of aggression. Proceedings of the National Academy of Sciences of the United States of America. 86: 8555-9. PMID 2813412  0.56
1989 Allen SJ, Dawbarn D, Spillantini MG, Goedert M, Wilcock GK, Moss TH, Semenenko FM. Distribution of beta-nerve growth factor receptors in the human basal forebrain. The Journal of Comparative Neurology. 289: 626-40. PMID 2556457 DOI: 10.1002/cne.902890408  0.56
1989 Goedert M, Fine A, Dawbarn D, Wilcock GK, Chao MV. Nerve growth factor receptor mRNA distribution in human brain: normal levels in basal forebrain in Alzheimer's disease. Brain Research. Molecular Brain Research. 5: 1-7. PMID 2538704 DOI: 10.1016/0169-328X(89)90011-9  0.56
1989 Spillantini MG, Hunt SP, Ulrich J, Goedert M. Expression and cellular localization of amyloid beta-protein precursor transcripts in normal human brain and in Alzheimer's disease. Brain Research. Molecular Brain Research. 6: 143-50. PMID 2515408 DOI: 10.1016/0169-328X(89)90048-X  0.56
1989 Goedert M, Spillantini MG, Potier MC, Ulrich J, Crowther RA. Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain. The Embo Journal. 8: 393-9. PMID 2498079  0.56
1989 Goedert M, Spillantini MG, Jakes R, Rutherford D, Crowther RA. Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron. 3: 519-26. PMID 2484340 DOI: 10.1016/0896-6273(89)90210-9  0.56
1988 Jackson TR, Blair LA, Marshall J, Goedert M, Hanley MR. The mas oncogene encodes an angiotensin receptor. Nature. 335: 437-40. PMID 3419518 DOI: 10.1038/335437a0  0.56
1988 Goedert M, Wischik CM, Crowther RA, Walker JE, Klug A. Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau. Proceedings of the National Academy of Sciences of the United States of America. 85: 4051-5. PMID 3131773  0.56
1987 Hunt SP, Goedert M. The cellular localization of mRNA in neurobiology. Biochemical Society Transactions. 15: 133. PMID 3556736  0.56
1987 Goedert M, Hunt SP. The cellular localization of preprotachykinin A messenger RNA in the bovine nervous system. Neuroscience. 22: 983-92. PMID 2446201  0.56
1986 Goedert M, Fine A, Hunt SP, Ullrich A. Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: lesion effects in the rat brain and levels in Alzheimer's disease. Brain Research. 387: 85-92. PMID 3742235 DOI: 10.1016/0169-328X(86)90023-9  0.56
1985 Goedert M, Schwartz WN, Williams BJ. The comparative distribution of [Lys8-Asn9]-neurotensin8-13-like immunoreactivity in chicken and rat tissues. Brain Research. 342: 259-65. PMID 4041826 DOI: 10.1016/0006-8993(85)91124-2  0.56
1985 Goedert M, Iversen SD, Emson PC. The effects of chronic neuroleptic treatment on neurotensin-like immunoreactivity in the rat central nervous system. Brain Research. 335: 334-6. PMID 4005561  0.96
1985 Goedert M, Lightman SL, Mantyh PW, Hunt SP, Emson PC. Neurotensin-like immunoreactivity and neurotensin receptors in the rat hypothalamus and in the neurointermediate lobe of the pituitary gland. Brain Research. 358: 59-69. PMID 3000519 DOI: 10.1016/0006-8993(85)90948-5  0.56
1985 Reeve JG, Goedert M, Emson PC, Bleehen NM. Neurotensin in human small cell lung carcinoma. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 99: 175-6. PMID 2999916  0.96
1985 Goedert M, Hunt SP, Mantyh PW, Emson PC. The ontogenetic development of neurotensin-like immunoreactivity and neurotensin receptors in the cat striatum. Brain Research. 352: 127-31. PMID 2988709 DOI: 10.1016/0165-3806(85)90095-1  0.56
1985 Emson PC, Horsfield PM, Goedert M, Rossor MN, Hawkes CH. Neurotensin in human brain: regional distribution and effects of neurological illness. Brain Research. 347: 239-44. PMID 2933123  0.96
1985 Fitzgerald M, Wall PD, Goedert M, Emson PC. Nerve growth factor counteracts the neurophysiological and neurochemical effects of chronic sciatic nerve section. Brain Research. 332: 131-41. PMID 2581648  0.96
1985 Hunter JC, Goedert M, Pinnock RD. Mammalian tachykinin-induced hydrolysis of inositol phospholipids in rat brain slices. Biochemical and Biophysical Research Communications. 127: 616-22. PMID 2579657 DOI: 10.1016/S0006-291X(85)80205-9  0.56
1984 Goedert M, Pittaway K, Williams BJ, Emson PC. Specific binding of tritiated neurotensin to rat brain membranes: characterization and regional distribution. Brain Research. 304: 71-81. PMID 6744039  0.96
1984 Goedert M, Lightman SL, Emson PC. Neurotensin in the rat anterior pituitary gland: effects of endocrinological manipulations. Brain Research. 299: 160-3. PMID 6722564  0.96
1984 Goedert M, Otten U, Hunt SP, Bond A, Chapman D, Schlumpf M, Lichtensteiger W. Biochemical and anatomical effects of antibodies against nerve growth factor on developing rat sensory ganglia. Proceedings of the National Academy of Sciences of the United States of America. 81: 1580-4. PMID 6608728  0.56
1984 Goedert M, Sturmey N, Williams BJ, Emson PC. The comparative distribution of xenopsin- and neurotensin-like immunoreactivity in Xenopus laevis and rat tissues. Brain Research. 308: 273-80. PMID 6434152  0.96
1984 Bannon MJ, Goedert M, Williams B. The possible relation of glutathione, melanin and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) to Parkinson's disease. Biochemical Pharmacology. 33: 2697-8. PMID 6331828 DOI: 10.1016/0006-2952(84)90682-8  0.56
1984 Goedert M, Mantyh PW, Hunt SP, Emson PC. Localization of specific neurotensin binding sites in the rat adrenal gland. Brain Research. 299: 389-92. PMID 6329423  0.96
1984 Mantyh PW, Goedert M, Hunt SP. Autoradiographic visualization of receptor binding sites for substance P in the gastrointestinal tract of the guinea pig. European Journal of Pharmacology. 100: 133-4. PMID 6327324  0.56
1984 Goedert M, Pittaway K, Emson PC. Neurotensin receptors in the rat striatum: lesion studies. Brain Research. 299: 164-8. PMID 6326960  0.96
1984 Marley PD, Lightman SL, Forsling ML, Todd K, Goedert M, Rehfeld JF, Emson PC. Localization and actions of cholecystokinin in the rat pituitary neurointermediate lobe. Endocrinology. 114: 1902-11. PMID 6325136 DOI: 10.1210/endo-114-5-1902  0.56
1984 Goedert M, Mantyh PW, Emson PC, Hunt SP. Inverse relationship between neurotensin receptors and neurotensin-like immunoreactivity in cat striatum. Nature. 307: 543-6. PMID 6320012 DOI: 10.1038/307543a0  0.56
1984 Mantyh PW, Pinnock RD, Downes CP, Goedert M, Hunt SP. Correlation between inositol phospholipid hydrolysis and substance P receptors in rat CNS. Nature. 309: 795-7. PMID 6204206 DOI: 10.1038/309795a0  0.56
1984 Bannon MJ, Goedert M. Changes in substance P concentrations after protein synthesis inhibition provide an index of substance P utilization. Brain Research. 301: 184-6. PMID 6203608 DOI: 10.1016/0006-8993(84)90421-9  0.56
1984 Goedert M, Hunter JC, Ninkovic M. Evidence for neurotensin as a non-adrenergic, non-cholinergic neurotransmitter in guinea pig ileum. Nature. 311: 59-62. PMID 6147756 DOI: 10.1038/311059a0  0.56
1984 Goedert M, Pinnock RD, Downes CP, Mantyh PW, Emson PC. Neurotensin stimulates inositol phospholipid hydrolysis in rat brain slices. Brain Research. 323: 193-7. PMID 6098333 DOI: 10.1016/0006-8993(84)90288-9  0.56
1984 Goedert M, Reeve JG, Emson PC, Bleehen NM. Neurotensin in human small cell lung carcinoma. British Journal of Cancer. 50: 179-83. PMID 6087865  0.96
1983 Goedert M, Reynolds GP, Emson PC. Neurotensin in the adrenal medulla. Neuroscience Letters. 35: 155-60. PMID 6856193  0.96
1983 Goedert M, Emson PC. The regional distribution of neurotensin-like immunoreactivity in central and peripheral tissues of the cat. Brain Research. 272: 291-7. PMID 6616204  0.96
1983 Goedert M, Mantyh PW, Hunt SP, Emson PC. Mosaic distribution of neurotensin-like immunoreactivity in the cat striatum. Brain Research. 274: 176-9. PMID 6351962  0.96
1983 Bannon MJ, Elliott PJ, Alpert JE, Goedert M, Iversen SD, Iversen LL. Role of endogenous substance P in stress-induced activation of mesocortical dopamine neurones. Nature. 306: 791-2. PMID 6197656 DOI: 10.1038/306791a0  0.56
1983 Nagy JI, Iversen LL, Goedert M, Chapman D, Hunt SP. Dose-dependent effects of capsaicin on primary sensory neurons in the neonatal rat. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 399-406. PMID 6185658  0.56
1982 Goedert M, Lightman SL, Nagy JI, Marley PD, Emson PC. Neurotensin in the rat anterior pituitary gland. Nature. 298: 163-5. PMID 7088171 DOI: 10.1038/298163a0  0.56
1982 Emson PC, Goedert M, Horsfield P, Rioux F, St Pierre S. The regional distribution and chromatographic characterisation of neurotensin-like immunoreactivity in the rat central nervous system. Journal of Neurochemistry. 38: 992-9. PMID 7062044  0.96
1982 Emson PC, Goedert M, Williams B, Ninkovic M, Hunt SP. Neurotensin: regional distribution, characterization, and inactivation. Annals of the New York Academy of Sciences. 400: 198-215. PMID 6762831  0.96
1982 Emson PC, Goedert M, Benton H, St-Pierre S, Rioux F. The regional distribution and chromatographic characterization of neurotensin-like immunoreactivity in the rat. Advances in Biochemical Psychopharmacology. 33: 477-85. PMID 6751035  0.96
1982 Nagy JI, Goedert M, Hunt SP, Bond A. The nature of the substance P-containing nerve fibres in taste papillae of the rat tongue. Neuroscience. 7: 3137-51. PMID 6186943  0.56
1982 Goedert M, Nagy JI, Emson PC. The origin of substance P in the rat submandibular gland and its major duct. Brain Research. 252: 327-33. PMID 6185178  0.96
1980 Goedert M, Otten U, Schäfer T, Schwab M, Thoenen H. Immunosympathectomy: lack of evidence for a complement-mediated cytotoxic mechanism. Brain Research. 201: 399-409. PMID 6106528 DOI: 10.1016/0006-8993(80)91043-4  0.56
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