☰

Patrick L. McGeer, MD, University of British Columbia 1958,PhD,Princeton 1951, OC, OBC, FRSC, FRCP(C) - Publications

Affiliations: 
Medicine University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=19
Website:
http://en.wikipedia.org/wiki/Pat_McGeer
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Year Citation  Score
2020 Wu J, Guo J, Du X, Mcgeer PL. Anti-inflammatory and neuroprotective effects of kissoone B and extracts of Valeriana amurensis Revista Brasileira De Farmacognosia-Brazilian Journal of Pharmacognosy. 30: 474-481. DOI: 10.1007/S43450-020-00037-1  0.303
2018 Sabbagh MN, Shi J, Lee M, Arnold L, Al-Hasan Y, Heim J, McGeer P. Salivary beta amyloid protein levels are detectable and differentiate patients with Alzheimer's disease dementia from normal controls: preliminary findings. Bmc Neurology. 18: 155. PMID 30257642 DOI: 10.1186/S12883-018-1160-Y  0.333
2018 McGeer PL, McGeer E. Conquering Alzheimer's Disease by Self Treatment. Journal of Alzheimer's Disease : Jad. PMID 29562519 DOI: 10.3233/Jad-179913  0.359
2017 McGeer PL, Guo JP, Lee M, Kennedy K, McGeer EG. Alzheimer's Disease Can Be Spared by Nonsteroidal Anti-Inflammatory Drugs. Journal of Alzheimer's Disease : Jad. PMID 29103042 DOI: 10.3233/Jad-170706  0.371
2017 De Lorenzi E, Chiari M, Colombo R, Cretich M, Sola L, Vanna R, Gagni P, Bisceglia F, Morasso C, Lin JS, Lee M, McGeer PL, Barron AE. Evidence that the Human Innate Immune Peptide LL-37 may be a Binding Partner of Amyloid-β and Inhibitor of Fibril Assembly. Journal of Alzheimer's Disease : Jad. PMID 28731438 DOI: 10.3233/Jad-170223  0.316
2017 Sabbagh MN, Shi J, Arnold L, McGeer P. [P2-255]: SALIVARY AMYLOID-BETA PROTEIN LEVELS CAN DIAGNOSE ALZHEIMER DISEASE AND PREDICT ITS FUTURE ONSET Alzheimer's & Dementia. 13: P710-P711. DOI: 10.1016/J.Jalz.2017.06.907  0.313
2016 McGeer PL, Lee M, McGeer EG. A review of human diseases caused or exacerbated by aberrant complement activation. Neurobiology of Aging. 52: 12-22. PMID 28104543 DOI: 10.1016/J.Neurobiolaging.2016.12.017  0.313
2016 Lee M, Guo JP, Kennedy K, McGeer EG, McGeer PL. A Method for Diagnosing Alzheimer's Disease Based on Salivary Amyloid-β Protein 42 Levels. Journal of Alzheimer's Disease : Jad. PMID 27792013 DOI: 10.3233/Jad-160748  0.357
2016 McGeer PL, Rogers J, McGeer EG. Inflammation, Antiinflammatory Agents, and Alzheimer's Disease: The Last 22 Years. Journal of Alzheimer's Disease : Jad. 54: 853-857. PMID 27716676 DOI: 10.3233/Jad-160488  0.39
2016 Lee M, McGeer EG, McGeer PL. Quercetin, not caffeine, is a major neuroprotective component in coffee. Neurobiology of Aging. 46: 113-123. PMID 27479153 DOI: 10.1016/J.Neurobiolaging.2016.06.015  0.365
2016 Lee M, McGeer EG, McGeer PL. Sodium thiosulfate attenuates glial-mediated neuroinflammation in degenerative neurological diseases. Journal of Neuroinflammation. 13: 32. PMID 26856696 DOI: 10.1186/S12974-016-0488-8  0.311
2015 Lee M, Wathier M, Love JA, McGeer E, McGeer PL. Inhibition of aberrant complement activation by a dimer of acetylsalicylic acid. Neurobiology of Aging. PMID 26248865 DOI: 10.1016/J.Neurobiolaging.2015.06.018  0.327
2015 Zhu A, Wu Z, Meng J, McGeer PL, Zhu Y, Nakanishi H, Wu S. The Neuroprotective Effects of Ratanasampil on Oxidative Stress-Mediated Neuronal Damage in Human Neuronal SH-SY5Y Cells. Oxidative Medicine and Cellular Longevity. 2015: 792342. PMID 26064424 DOI: 10.1155/2015/792342  0.317
2015 O'Hare E, Jeggo R, Kim EM, Barbour B, Walczak JS, Palmer P, Lyons T, Page D, Hanna D, Meara JR, Spanswick D, Guo JP, McGeer EG, McGeer PL, Hobson P. Lack of support for bexarotene as a treatment for Alzheimer's disease. Neuropharmacology. PMID 26025659 DOI: 10.1016/J.Neuropharm.2015.04.020  0.349
2015 Hashioka S, McGeer EG, Miyaoka T, Wake R, Horiguchi J, McGeer PL. Interferon-γ-induced neurotoxicity of human astrocytes. Cns & Neurological Disorders Drug Targets. 14: 251-6. PMID 25687700 DOI: 10.2174/1871527314666150217122305  0.375
2015 Lee M, Shi X, Barron AE, McGeer E, McGeer PL. Human antimicrobial peptide LL-37 induces glial-mediated neuroinflammation. Biochemical Pharmacology. 94: 130-41. PMID 25686659 DOI: 10.1016/J.Bcp.2015.02.003  0.355
2015 McGeer PL, McGeer EG. Targeting microglia for the treatment of Alzheimer's disease. Expert Opinion On Therapeutic Targets. 19: 497-506. PMID 25435348 DOI: 10.1517/14728222.2014.988707  0.361
2015 Lee M, McGeer E, McGeer PL. Activated human microglia stimulate neuroblastoma cells to upregulate production of beta amyloid protein and tau: implications for Alzheimer's disease pathogenesis. Neurobiology of Aging. 36: 42-52. PMID 25169677 DOI: 10.1016/J.Neurobiolaging.2014.07.024  0.384
2013 McGeer PL, McGeer EG. The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy. Acta Neuropathologica. 126: 479-97. PMID 24052108 DOI: 10.1007/S00401-013-1177-7  0.393
2013 Jantaratnotai N, Ling A, Cheng J, Schwab C, McGeer PL, McLarnon JG. Upregulation and expression patterns of the angiogenic transcription factor ets-1 in Alzheimer's disease brain. Journal of Alzheimer's Disease : Jad. 37: 367-77. PMID 23948889 DOI: 10.3233/Jad-122191  0.35
2013 Lee M, McGeer E, Kodela R, Kashfi K, McGeer PL. NOSH-aspirin (NBS-1120), a novel nitric oxide and hydrogen sulfide releasing hybrid, attenuates neuroinflammation induced by microglial and astrocytic activation: a new candidate for treatment of neurodegenerative disorders. Glia. 61: 1724-34. PMID 23918470 DOI: 10.1002/Glia.22553  0.337
2013 Wu Z, Sun L, Hashioka S, Yu S, Schwab C, Okada R, Hayashi Y, McGeer PL, Nakanishi H. Differential pathways for interleukin-1β production activated by chromogranin A and amyloid β in microglia. Neurobiology of Aging. 34: 2715-25. PMID 23831373 DOI: 10.1016/J.Neurobiolaging.2013.05.018  0.313
2013 Lee M, Guo JP, McGeer EG, McGeer PL. Aurin tricarboxylic acid self-protects by inhibiting aberrant complement activation at the C3 convertase and C9 binding stages. Neurobiology of Aging. 34: 1451-61. PMID 23177218 DOI: 10.1016/J.Neurobiolaging.2012.10.023  0.304
2013 Schwab C, Yu S, Wong W, McGeer EG, McGeer PL. GAD65, GAD67, and GABAT immunostaining in human brain and apparent GAD65 loss in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 33: 1073-88. PMID 23114513 DOI: 10.3233/Jad-2012-121330  0.398
2013 Lee M, McGeer E, McGeer PL. Neurotoxins released from interferon-gamma-stimulated human astrocytes. Neuroscience. 229: 164-75. PMID 23098801 DOI: 10.1016/J.Neuroscience.2012.10.033  0.37
2012 Hashioka S, Klegeris A, McGeer PL. Inhibition of human astrocyte and microglia neurotoxicity by calcium channel blockers. Neuropharmacology. 63: 685-91. PMID 22659089 DOI: 10.1016/J.Neuropharm.2012.05.033  0.318
2012 Lee M, Guo JP, Schwab C, McGeer EG, McGeer PL. Selective inhibition of the membrane attack complex of complement by low molecular weight components of the aurin tricarboxylic acid synthetic complex. Neurobiology of Aging. 33: 2237-46. PMID 22217416 DOI: 10.1016/J.Neurobiolaging.2011.12.005  0.311
2012 Schwab C, Yu S, McGeer PL. Optineurin is colocalized with ubiquitin in Marinesco bodies. Acta Neuropathologica. 123: 289-92. PMID 22101367 DOI: 10.1007/S00401-011-0915-Y  0.358
2012 Schwab C, Yu S, McGeer EG, McGeer PL. Optineurin in Huntington's disease intranuclear inclusions. Neuroscience Letters. 506: 149-54. PMID 22085693 DOI: 10.1016/J.Neulet.2011.10.070  0.326
2012 Lee M, Kwon BM, Kwon BM, Suk K, McGeer E, McGeer PL. Effects of obovatol on GSH depleted glia-mediated neurotoxicity and oxidative damage. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 173-86. PMID 21796424 DOI: 10.1007/S11481-011-9300-9  0.327
2012 Lee M, McGeer PL. Weak BMAA toxicity compares with that of the dietary supplement β-alanine. Neurobiology of Aging. 33: 1440-7. PMID 21236519 DOI: 10.1016/J.Neurobiolaging.2010.11.024  0.318
2012 Lee M, Schwab C, Yu S, McGeer E, McGeer P. P3-392: Induction of neuronal tau expression by conditioned medium from activated microglial cells Alzheimer's & Dementia. 8: P593-P593. DOI: 10.1016/J.Jalz.2012.05.2066  0.305
2012 Lee M, Guo J, Schwab C, McGeer E, McGeer P. P2-434: Aurin tricarboxylic acid may help Alzheimer's disease and other conditions by blocking the MAC of complement Alzheimer's & Dementia. 8: P418-P418. DOI: 10.1016/J.Jalz.2012.05.2059  0.322
2012 Schwab C, Yu S, Wong W, McGeer E, McGeer P. P2-417: GAD65, GAD67 and GABAT immunoreactivity in human brain and GAD65 loss in Alzheimer's disease Alzheimer's & Dementia. 8: P410-P410. DOI: 10.1016/J.Jalz.2012.05.2042  0.369
2012 Mclarnon J, Ling A, Jantaratnotai N, Schwab C, McGeer P. P4-044: Immunostaining evidence for angiogenic activity in Alzheimer's disease brain tissue Alzheimer's & Dementia. 8: P651-P651. DOI: 10.1016/J.Jalz.2012.05.1745  0.351
2011 McGeer PL, McGeer EG. History of innate immunity in neurodegenerative disorders. Frontiers in Pharmacology. 2: 77. PMID 22144960 DOI: 10.3389/Fphar.2011.00077  0.31
2011 Lee M, Kang Y, Suk K, Schwab C, Yu S, McGeer PL. Acidic fibroblast growth factor (FGF) potentiates glial-mediated neurotoxicity by activating FGFR2 IIIb protein. The Journal of Biological Chemistry. 286: 41230-45. PMID 21990352 DOI: 10.1074/Jbc.M111.270470  0.357
2011 Jantaratnotai N, Ryu JK, Schwab C, McGeer PL, McLarnon JG. Comparison of Vascular Perturbations in an Aβ-Injected Animal Model and in AD Brain. International Journal of Alzheimer's Disease. 2011: 918280. PMID 21969915 DOI: 10.4061/2011/918280  0.376
2011 Zou WQ, Xiao X, Yuan J, Puoti G, Fujioka H, Wang X, Richardson S, Zhou X, Zou R, Li S, Zhu X, McGeer PL, McGeehan J, Kneale G, Rincon-Limas DE, et al. Amyloid-beta42 interacts mainly with insoluble prion protein in the Alzheimer brain. The Journal of Biological Chemistry. 286: 15095-105. PMID 21393248 DOI: 10.1074/Jbc.M110.199356  0.355
2011 Hashioka S, Klegeris A, McGeer PL. Proton pump inhibitors reduce interferon-γ-induced neurotoxicity and STAT3 phosphorylation of human astrocytes. Glia. 59: 833-40. PMID 21360757 DOI: 10.1002/Glia.21157  0.31
2010 Jantaratnotai N, Schwab C, Ryu JK, McGeer PL, McLarnon JG. Converging perturbed microvasculature and microglial clusters characterize Alzheimer disease brain. Current Alzheimer Research. 7: 625-36. PMID 20704556 DOI: 10.2174/156720510793499039  0.325
2010 Morawski M, Hartlage-Rübsamen M, Jäger C, Waniek A, Schilling S, Schwab C, McGeer PL, Arendt T, Demuth HU, Rossner S. Distinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer's disease. Acta Neuropathologica. 120: 195-207. PMID 20383514 DOI: 10.1007/S00401-010-0685-Y  0.398
2010 Lee M, Tazzari V, Giustarini D, Rossi R, Sparatore A, Del Soldato P, McGeer E, McGeer PL. Effects of hydrogen sulfide-releasing L-DOPA derivatives on glial activation: potential for treating Parkinson disease. The Journal of Biological Chemistry. 285: 17318-28. PMID 20368333 DOI: 10.1074/Jbc.M110.115261  0.3
2010 Lee M, Cho T, Jantaratnotai N, Wang YT, McGeer E, McGeer PL. Depletion of GSH in glial cells induces neurotoxicity: relevance to aging and degenerative neurological diseases. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2533-45. PMID 20228251 DOI: 10.1096/Fj.09-149997  0.351
2010 McGeer EG, McGeer PL. Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy. Journal of Alzheimer's Disease : Jad. 19: 355-61. PMID 20061650 DOI: 10.3233/Jad-2010-1219  0.383
2010 Guo JP, Yu S, McGeer PL. Simple in vitro assays to identify amyloid-beta aggregation blockers for Alzheimer's disease therapy. Journal of Alzheimer's Disease : Jad. 19: 1359-70. PMID 20061605 DOI: 10.3233/Jad-2010-1331  0.343
2010 Schwab C, Klegeris A, McGeer PL. Inflammation in transgenic mouse models of neurodegenerative disorders. Biochimica Et Biophysica Acta. 1802: 889-902. PMID 19883753 DOI: 10.1016/J.Bbadis.2009.10.013  0.348
2010 Lee M, Sparatore A, Del Soldato P, McGeer E, McGeer PL. Hydrogen sulfide-releasing NSAIDs attenuate neuroinflammation induced by microglial and astrocytic activation. Glia. 58: 103-13. PMID 19544392 DOI: 10.1002/Glia.20905  0.317
2010 Miklossy J, Qing H, Radenovic A, Kis A, Vileno B, Làszló F, Miller L, Martins RN, Waeber G, Mooser V, Bosman F, Khalili K, Darbinian N, McGeer PL. Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes. Neurobiology of Aging. 31: 1503-15. PMID 18950899 DOI: 10.1016/J.Neurobiolaging.2008.08.019  0.316
2009 Hashioka S, McGeer PL, Monji A, Kanba S. Anti-inflammatory effects of antidepressants: possibilities for preventives against Alzheimer's disease. Central Nervous System Agents in Medicinal Chemistry. 9: 12-9. PMID 20021334 DOI: 10.2174/187152409787601897  0.331
2009 Lee M, Schwab C, Yu S, McGeer E, McGeer PL. Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide. Neurobiology of Aging. 30: 1523-34. PMID 19631409 DOI: 10.1016/J.Neurobiolaging.2009.06.001  0.322
2009 Ludolph AC, Kassubek J, Landwehrmeyer BG, Mandelkow E, Mandelkow EM, Burn DJ, Caparros-Lefebvre D, Frey KA, de Yebenes JG, Gasser T, Heutink P, Höglinger G, Jamrozik Z, Jellinger KA, Kazantsev A, ... ... McGeer PL, et al. Tauopathies with parkinsonism: clinical spectrum, neuropathologic basis, biological markers, and treatment options. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 16: 297-309. PMID 19364361 DOI: 10.1111/J.1468-1331.2008.02513.X  0.338
2009 Schwab C, Arai T, Hasegawa M, Akiyama H, Yu S, McGeer PL. TDP-43 pathology in familial British dementia. Acta Neuropathologica. 118: 303-11. PMID 19283396 DOI: 10.1007/S00401-009-0514-3  0.357
2009 Hashioka S, Klegeris A, McGeer PL. Proton pump inhibitors exert anti-inflammatory effects and decrease human microglial and monocytic THP-1 cell neurotoxicity. Experimental Neurology. 217: 177-83. PMID 19232345 DOI: 10.1016/J.Expneurol.2009.02.002  0.315
2009 Hashioka S, Klegeris A, Schwab C, McGeer PL. Interferon-gamma-dependent cytotoxic activation of human astrocytes and astrocytoma cells. Neurobiology of Aging. 30: 1924-35. PMID 18375019 DOI: 10.1016/J.Neurobiolaging.2008.02.019  0.362
2009 Hashioka S, McGeer PL. Complexity of microglial activation state: Can modifying microglial activation treat Alzheimer's disease? Future Neurology. 4: 137-139. DOI: 10.2217/14796708.4.2.137  0.32
2008 Schwab C, Arai T, Hasegawa M, Yu S, McGeer PL. Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease. Journal of Neuropathology and Experimental Neurology. 67: 1159-65. PMID 19018245 DOI: 10.1097/Nen.0B013E31818E8951  0.344
2008 Miklossy J, Steele JC, Yu S, McCall S, Sandberg G, McGeer EG, McGeer PL. Enduring involvement of tau, beta-amyloid, alpha-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam (ALS/PDC). Acta Neuropathologica. 116: 625-37. PMID 18843496 DOI: 10.1007/S00401-008-0439-2  0.363
2008 Gnjec A, D'Costa KJ, Laws SM, Hedley R, Balakrishnan K, Taddei K, Martins G, Paton A, Verdile G, Gandy SE, Broe GA, Brooks WS, Bennett H, Piguet O, Price P, ... ... McGeer PL, et al. Association of alleles carried at TNFA -850 and BAT1 -22 with Alzheimer's disease. Journal of Neuroinflammation. 5: 36. PMID 18715507 DOI: 10.1186/1742-2094-5-36  0.377
2008 Hashioka S, Miklossy J, Schwab C, Klegeris A, McGeer PL. Adhesion of exogenous human microglia and THP-1 cells to amyloid plaques of postmortem Alzheimer's disease brain. Journal of Alzheimer's Disease : Jad. 14: 345-52. PMID 18599961 DOI: 10.3233/Jad-2008-14309  0.386
2008 Villoslada P, Moreno B, Melero I, Pablos JL, Martino G, Uccelli A, Montalban X, Avila J, Rivest S, Acarin L, Appel S, Khoury SJ, McGeer P, Ferrer I, Delgado M, et al. Immunotherapy for neurological diseases. Clinical Immunology (Orlando, Fla.). 128: 294-305. PMID 18534912 DOI: 10.1016/J.Clim.2008.04.003  0.301
2008 McGeer PL, McGeer EG. The alpha-synuclein burden hypothesis of Parkinson disease and its relationship to Alzheimer disease. Experimental Neurology. 212: 235-8. PMID 18514193 DOI: 10.1016/J.Expneurol.2008.04.008  0.317
2008 Schwab C, McGeer PL. Inflammatory aspects of Alzheimer disease and other neurodegenerative disorders. Journal of Alzheimer's Disease : Jad. 13: 359-69. PMID 18487845 DOI: 10.3233/Jad-2008-13402  0.309
2008 Klegeris A, Li J, Bammler TK, Jin J, Zhu D, Kashima DT, Pan S, Hashioka S, Maguire J, McGeer PL, Zhang J. Prolyl endopeptidase is revealed following SILAC analysis to be a novel mediator of human microglial and THP-1 cell neurotoxicity. Glia. 56: 675-85. PMID 18293395 DOI: 10.1002/Glia.20645  0.319
2008 McGeer PL, McGeer EG. Glial reactions in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 23: 474-83. PMID 18044695 DOI: 10.1002/Mds.21751  0.323
2008 Miklossy J, Fein LA, McCall S, Kasas S, McGeer PL. P1-378: Concurrent Alzheimer's disease and Lyme neuroborreliosis: Persisting atypical cystic Forms of Borrelia burgdorferi in the brain and recovery of cognitive decline following antibiotic treatment Alzheimer's & Dementia. 4: T329-T330. DOI: 10.1016/J.Jalz.2008.05.960  0.321
2007 McGeer EG, McGeer PL. The role of anti-inflammatory agents in Parkinson's disease. Cns Drugs. 21: 789-97. PMID 17850169 DOI: 10.2165/00023210-200721100-00001  0.363
2007 Miklossy J, Qing H, Guo JP, Yu S, Wszolek ZK, Calne D, McGeer EG, McGeer PL. Lrrk2 and chronic inflammation are linked to pallido-ponto-nigral degeneration caused by the N279K tau mutation. Acta Neuropathologica. 114: 243-54. PMID 17639429 DOI: 10.1007/S00401-007-0230-9  0.37
2007 Klegeris A, Choi HB, McLarnon JG, McGeer PL. Functional ryanodine receptors are expressed by human microglia and THP-1 cells: Their possible involvement in modulation of neurotoxicity. Journal of Neuroscience Research. 85: 2207-15. PMID 17526017 DOI: 10.1002/Jnr.21361  0.326
2007 Klegeris A, McGeer EG, McGeer PL. Therapeutic approaches to inflammation in neurodegenerative disease. Current Opinion in Neurology. 20: 351-7. PMID 17495632 DOI: 10.1097/Wco.0B013E3280Adc943  0.319
2007 Klegeris A, McGeer PL. Complement activation by islet amyloid polypeptide (IAPP) and alpha-synuclein 112. Biochemical and Biophysical Research Communications. 357: 1096-9. PMID 17459337 DOI: 10.1016/J.Bbrc.2007.04.055  0.337
2007 Klegeris A, Schulzer M, Harper DG, McGeer PL. Increase in core body temperature of Alzheimer's disease patients as a possible indicator of chronic neuroinflammation: a meta-analysis. Gerontology. 53: 7-11. PMID 16940734 DOI: 10.1159/000095386  0.379
2007 McGeer PL, McGeer EG. NSAIDs and Alzheimer disease: epidemiological, animal model and clinical studies. Neurobiology of Aging. 28: 639-47. PMID 16697488 DOI: 10.1016/J.Neurobiolaging.2006.03.013  0.337
2006 Miklossy J, Arai T, Guo JP, Klegeris A, Yu S, McGeer EG, McGeer PL. LRRK2 expression in normal and pathologic human brain and in human cell lines. Journal of Neuropathology and Experimental Neurology. 65: 953-63. PMID 17021400 DOI: 10.1097/01.Jnen.0000235121.98052.54  0.402
2006 McGeer PL, Rogers J, McGeer EG. Inflammation, anti-inflammatory agents and Alzheimer disease: the last 12 years. Journal of Alzheimer's Disease : Jad. 9: 271-6. PMID 16914866 DOI: 10.3233/Jad-2006-9S330  0.373
2006 Guo JP, Arai T, Miklossy J, McGeer PL. Abeta and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 1953-8. PMID 16446437 DOI: 10.1073/Pnas.0509386103  0.341
2006 Arai T, Miklossy J, Klegeris A, Guo JP, McGeer PL. Thrombin and prothrombin are expressed by neurons and glial cells and accumulate in neurofibrillary tangles in Alzheimer disease brain. Journal of Neuropathology and Experimental Neurology. 65: 19-25. PMID 16410745 DOI: 10.1097/01.Jnen.0000196133.74087.Cb  0.413
2005 McGeer EG, McGeer PL. Abeta immunotherapy and other means to remove amyloid. Current Drug Targets. Cns and Neurological Disorders. 4: 569-73. PMID 16266289 DOI: 10.2174/156800705774322067  0.336
2005 McGeer EG, Klegeris A, McGeer PL. Inflammation, the complement system and the diseases of aging. Neurobiology of Aging. 26: 94-7. PMID 16198446 DOI: 10.1016/J.Neurobiolaging.2005.08.008  0.37
2005 Klegeris A, McGeer PL. Non-steroidal anti-inflammatory drugs (NSAIDs) and other anti-inflammatory agents in the treatment of neurodegenerative disease. Current Alzheimer Research. 2: 355-65. PMID 15974901 DOI: 10.2174/1567205054367883  0.373
2005 Miklossy J, Mackenzie IR, Dorovini-Zis K, Calne DB, Wszolek ZK, Klegeris A, McGeer PL. Severe vascular disturbance in a case of familial brain calcinosis. Acta Neuropathologica. 109: 643-53. PMID 15937691 DOI: 10.1007/S00401-005-1007-7  0.309
2005 Klegeris A, McGeer PL. Chymotrypsin-like proteases contribute to human monocytic THP-1 cell as well as human microglial neurotoxicity. Glia. 51: 56-64. PMID 15779083 DOI: 10.1002/Glia.20186  0.391
2005 McGeer EG, McGeer PL. Pharmacologic approaches to the treatment of amyotrophic lateral sclerosis. Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. 19: 31-7. PMID 15691215 DOI: 10.2165/00063030-200519010-00004  0.302
2005 Arai T, Guo JP, McGeer PL. Proteolysis of non-phosphorylated and phosphorylated tau by thrombin. The Journal of Biological Chemistry. 280: 5145-53. PMID 15542598 DOI: 10.1074/Jbc.M409234200  0.35
2004 McGeer PL, McGeer EG. Inflammation and the degenerative diseases of aging. Annals of the New York Academy of Sciences. 1035: 104-16. PMID 15681803 DOI: 10.1196/Annals.1332.007  0.381
2004 Hosokawa M, Klegeris A, McGeer PL. Human oligodendroglial cells express low levels of C1 inhibitor and membrane cofactor protein mRNAs. Journal of Neuroinflammation. 1: 17. PMID 15327690 DOI: 10.1186/1742-2094-1-17  0.308
2004 McGeer PL, McGeer E. Immunotherapy for Alzheimer's disease. Science of Aging Knowledge Environment : Sage Ke. 2004: pe29. PMID 15243154 DOI: 10.1126/Sageke.2004.27.Pe29  0.381
2004 Klegeris A, Maguire J, McGeer PL. S- but not R-enantiomers of flurbiprofen and ibuprofen reduce human microglial and THP-1 cell neurotoxicity. Journal of Neuroimmunology. 152: 73-7. PMID 15223239 DOI: 10.1016/J.Jneuroim.2004.04.001  0.329
2004 Schwab C, Hosokawa M, McGeer PL. Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease. Experimental Neurology. 188: 52-64. PMID 15191802 DOI: 10.1016/J.Expneurol.2004.03.016  0.338
2004 McGeer PL, McGeer EG. Inflammation and neurodegeneration in Parkinson's disease. Parkinsonism & Related Disorders. 10: S3-7. PMID 15109580 DOI: 10.1016/J.Parkreldis.2004.01.005  0.31
2004 Akiyama H, McGeer PL. Specificity of mechanisms for plaque removal after A beta immunotherapy for Alzheimer disease. Nature Medicine. 10: 117-8; author reply . PMID 14760408 DOI: 10.1038/Nm0204-117  0.315
2004 Akiyama H, Kondo H, Arai T, Ikeda K, Kato M, Iseki E, Schwab C, McGeer PL. Expression of BRI, the normal precursor of the amyloid protein of familial British dementia, in human brain. Acta Neuropathologica. 107: 53-8. PMID 14586629 DOI: 10.1007/S00401-003-0783-1  0.393
2004 Miklossy J, Arai T, Schwab C, Steele JC, McGeer PL. P3-368 Neuronal and glial fibrillary tangles in parkinsonism dementia of Guam are more extensive and severe than in Alzheimer disease and other tauopathies Neurobiology of Aging. 25: S460. DOI: 10.1016/S0197-4580(04)81517-3  0.36
2004 Miklossy J, Reiss K, Darbinian N, Khalili K, McGeer PL, Miklossy J. P2-136 Lipopolysaccharide (LPS) simultaneously induces the two most important biological markers of Alzheimer's disease Neurobiology of Aging. 25: S263. DOI: 10.1016/S0197-4580(04)80883-2  0.308
2003 McGeer PL, Schwab C, Parent A, Doudet D. Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration. Annals of Neurology. 54: 599-604. PMID 14595649 DOI: 10.1002/Ana.10728  0.307
2003 McGeer EG, McGeer PL. Inflammatory processes in Alzheimer's disease. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 27: 741-9. PMID 12921904 DOI: 10.1016/S0278-5846(03)00124-6  0.415
2003 Schwab C, Hosokawa M, Akiyama H, McGeer PL. Familial British dementia: colocalization of furin and ABri amyloid. Acta Neuropathologica. 106: 278-84. PMID 12883829 DOI: 10.1007/S00401-003-0735-9  0.379
2003 McGeer EG, McGeer PL. Clinically tested drugs for Alzheimer's disease. Expert Opinion On Investigational Drugs. 12: 1143-51. PMID 12831349 DOI: 10.1517/13543784.12.7.1143  0.36
2003 Klegeris A, McGeer PL. Toxicity of human monocytic THP-1 cells and microglia toward SH-SY5Y neuroblastoma cells is reduced by inhibitors of 5-lipoxygenase and its activating protein FLAP. Journal of Leukocyte Biology. 73: 369-78. PMID 12629151 DOI: 10.1189/Jlb.1002482  0.322
2003 McGeer PL, McGeer E. Is there a future for vaccination as a treatment for Alzheimer's disease? Neurobiology of Aging. 24: 391-5. PMID 12600715 DOI: 10.1016/S0197-4580(02)00157-4  0.317
2002 McGeer PL, McGeer EG. Innate immunity, local inflammation, and degenerative disease. Science of Aging Knowledge Environment : Sage Ke. 2002: re3. PMID 14602998 DOI: 10.1126/Sageke.2002.29.Re3  0.389
2002 McGeer PL, McGeer EG. Local neuroinflammation and the progression of Alzheimer's disease. Journal of Neurovirology. 8: 529-38. PMID 12476347 DOI: 10.1080/13550280290100969  0.381
2002 McGeer PL, McGeer EG. The possible role of complement activation in Alzheimer disease. Trends in Molecular Medicine. 8: 519-23. PMID 12421685 DOI: 10.1016/S1471-4914(02)02422-X  0.383
2002 Klegeris A, McGeer PL. Cyclooxygenase and 5-lipoxygenase inhibitors protect against mononuclear phagocyte neurotoxicity. Neurobiology of Aging. 23: 787-94. PMID 12392782 DOI: 10.1016/S0197-4580(02)00021-0  0.345
2002 Morris HR, Baker M, Yasojima K, Houlden H, Khan MN, Wood NW, Hardy J, Grossman M, Trojanowski J, Revesz T, Bigio EH, Bergeron C, Janssen JC, McGeer PL, Rossor MN, et al. Analysis of tau haplotypes in Pick's disease. Neurology. 59: 443-5. PMID 12177383 DOI: 10.1212/Wnl.59.3.443  0.308
2002 Klegeris A, Liutkevicius E, Mikalauskiene G, Duburs G, McGeer PL, Klusa V. Anti-inflammatory effects of cerebrocrast in a model of rat paw edema and on mononuclear THP-1 cells. European Journal of Pharmacology. 441: 203-8. PMID 12063093 DOI: 10.1016/S0014-2999(02)01262-1  0.352
2001 McGeer EG, McGeer PL. Chronic inflammation in Alzheimer's disease offers therapeutic opportunities. Expert Review of Neurotherapeutics. 1: 53-60. PMID 19811046 DOI: 10.1586/14737175.1.1.53  0.398
2001 McGeer EG, Yasojima K, Schwab C, McGeer PL. The pentraxins: possible role in Alzheimer's disease and other innate inflammatory diseases. Neurobiology of Aging. 22: 843-8. PMID 11754991 DOI: 10.1016/S0197-4580(01)00288-3  0.409
2001 McGeer PL, McGeer EG. Polymorphisms in inflammatory genes and the risk of Alzheimer disease. Archives of Neurology. 58: 1790-2. PMID 11708985 DOI: 10.1001/Archneur.58.11.1790  0.322
2001 Akiyama H, Kondo H, Ikeda K, Kato M, McGeer PL. Immunohistochemical localization of neprilysin in the human cerebral cortex: inverse association with vulnerability to amyloid beta-protein (Abeta) deposition. Brain Research. 902: 277-81. PMID 11384622 DOI: 10.1016/S0006-8993(01)02390-3  0.339
2001 Arai T, Ikeda K, Akiyama H, Shikamoto Y, Tsuchiya K, Yagishita S, Beach T, Rogers J, Schwab C, McGeer PL. Distinct isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick's disease, corticobasal degeneration and progressive supranuclear palsy. Acta Neuropathologica. 101: 167-73. PMID 11271372 DOI: 10.1007/S004010000283  0.382
2001 Yasojima K, Akiyama H, McGeer EG, McGeer PL. Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of beta-amyloid peptide. Neuroscience Letters. 297: 97-100. PMID 11121879 DOI: 10.1016/S0304-3940(00)01675-X  0.368
2000 Yasojima K, Schwab C, McGeer EG, McGeer PL. Human neurons generate C-reactive protein and amyloid P: upregulation in Alzheimer's disease. Brain Research. 887: 80-9. PMID 11134592 DOI: 10.1016/S0006-8993(00)02970-X  0.407
2000 Klegeris A, McGeer PL. R-(-)-Deprenyl inhibits monocytic THP-1 cell neurotoxicity independently of monoamine oxidase inhibition. Experimental Neurology. 166: 458-64. PMID 11085911 DOI: 10.1006/Exnr.2000.7517  0.319
2000 McGeer PL, McGeer EG, Yasojima K. Alzheimer disease and neuroinflammation. Journal of Neural Transmission. Supplementum. 59: 53-7. PMID 10961418 DOI: 10.1007/978-3-7091-6781-6_8  0.402
2000 McGeer PL. Cyclo-oxygenase-2 inhibitors: rationale and therapeutic potential for Alzheimer's disease. Drugs & Aging. 17: 1-11. PMID 10933512 DOI: 10.2165/00002512-200017010-00001  0.37
2000 Schwab C, DeMaggio AJ, Ghoshal N, Binder LI, Kuret J, McGeer PL. Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative diseases. Neurobiology of Aging. 21: 503-10. PMID 10924763 DOI: 10.1016/S0197-4580(00)00110-X  0.354
2000 Cooper NR, Kalaria RN, McGeer PL, Rogers J. Key issues in Alzheimer's disease inflammation. Neurobiology of Aging. 21: 451-453. PMID 10858594 DOI: 10.1016/S0197-4580(00)00148-2  0.353
2000 Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, Cooper NR, Eikelenboom P, Emmerling M, Fiebich BL, Finch CE, Frautschy S, Griffin WS, Hampel H, Hull M, ... ... McGeer PL, et al. Inflammation and Alzheimer's disease. Neurobiology of Aging. 21: 383-421. PMID 10858586 DOI: 10.1016/S0197-4580(00)00124-X  0.388
2000 Yasojima K, Kuret J, DeMaggio AJ, McGeer E, McGeer PL. Casein kinase 1 delta mRNA is upregulated in Alzheimer disease brain. Brain Research. 865: 116-20. PMID 10814741 DOI: 10.1016/S0006-8993(00)02200-9  0.382
2000 Klegeris A, McGeer EG, McGeer PL. Inhibitory action of 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxam ide (PK 11195) on some mononuclear phagocyte functions. Biochemical Pharmacology. 59: 1305-14. PMID 10736431 DOI: 10.1016/S0006-2952(00)00252-5  0.305
2000 Klegeris A, McGeer PL. Interaction of various intracellular signaling mechanisms involved in mononuclear phagocyte toxicity toward neuronal cells. Journal of Leukocyte Biology. 67: 127-33. PMID 10648007 DOI: 10.1002/Jlb.67.1.127  0.363
1999 Schwab C, Schulzer M, Steele JC, McGeer PL. On the survival time of a tangled neuron in the hippocampal CA4 region in parkinsonism dementia complex of Guam. Neurobiology of Aging. 20: 57-63. PMID 10466894 DOI: 10.1016/S0197-4580(99)00005-6  0.327
1999 Klegeris A, Walker DG, McGeer PL. Toxicity of human THP-1 monocytic cells towards neuron-like cells is reduced by non-steroidal anti-inflammatory drugs (NSAIDs). Neuropharmacology. 38: 1017-25. PMID 10428420 DOI: 10.1016/S0028-3908(99)00014-3  0.356
1999 Yasojima K, McGeer EG, McGeer PL. Complement regulators C1 inhibitor and CD59 do not significantly inhibit complement activation in Alzheimer disease. Brain Research. 833: 297-301. PMID 10375708 DOI: 10.1016/S0006-8993(99)01514-0  0.316
1999 Yasojima K, Schwab C, McGeer EG, McGeer PL. Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs. Brain Research. 830: 226-36. PMID 10366679 DOI: 10.1016/S0006-8993(99)01389-X  0.379
1999 McGeer PL, McGeer EG. Inflammation of the brain in Alzheimer's disease: implications for therapy. Journal of Leukocyte Biology. 65: 409-15. PMID 10204568 DOI: 10.1002/Jlb.65.4.409  0.402
1999 Yasojima K, Schwab C, McGeer EG, McGeer PL. Up-regulated production and activation of the complement system in Alzheimer's disease brain. The American Journal of Pathology. 154: 927-36. PMID 10079271 DOI: 10.1016/S0002-9440(10)65340-0  0.357
1999 Akiyama H, Mori H, Saido T, Kondo H, Ikeda K, McGeer PL. Occurrence of the diffuse amyloid beta-protein (Abeta) deposits with numerous Abeta-containing glial cells in the cerebral cortex of patients with Alzheimer's disease. Glia. 25: 324-31. PMID 10028915 DOI: 10.1002/(Sici)1098-1136(19990215)25:4<324::Aid-Glia2>3.0.Co;2-5  0.333
1998 Schwab C, Akiyama H, McGeer EG, McGeer PL. Extracellular neurofibrillary tangles are immunopositive for the 40 carboxy-terminal sequence of beta-amyloid protein. Journal of Neuropathology and Experimental Neurology. 57: 1131-7. PMID 9862635 DOI: 10.1097/00005072-199812000-00004  0.338
1998 McGeer PL, McGeer EG. Mechanisms of cell death in Alzheimer disease--immunopathology. Journal of Neural Transmission. Supplementum. 54: 159-66. PMID 9850924 DOI: 10.1007/978-3-7091-7508-8_15  0.302
1998 Walker DG, Kim SU, McGeer PL. Expression of complement C4 and C9 genes by human astrocytes. Brain Research. 809: 31-8. PMID 9795119 DOI: 10.1016/S0006-8993(98)00811-7  0.323
1998 McGeer PL, McGeer EG. Glial cell reactions in neurodegenerative diseases: pathophysiology and therapeutic interventions. Alzheimer Disease and Associated Disorders. 12: S1-6. PMID 9769023 DOI: 10.1097/00002093-199803001-00001  0.413
1998 McGeer EG, McGeer PL. The importance of inflammatory mechanisms in Alzheimer disease. Experimental Gerontology. 33: 371-8. PMID 9762518 DOI: 10.1016/S0531-5565(98)00013-8  0.416
1998 Takami K, Matsuo A, Terai K, Walker DG, McGeer EG, McGeer PL. Fibroblast growth factor receptor-1 expression in the cortex and hippocampus in Alzheimer's disease. Brain Research. 802: 89-97. PMID 9748519 DOI: 10.1016/S0006-8993(98)00552-6  0.373
1998 McGeer PL, Kawamata T, McGeer EG. Localization and possible functions of presenilins in brain. Reviews in the Neurosciences. 9: 1-15. PMID 9683324 DOI: 10.1515/Revneuro.1998.9.1.1  0.376
1998 Walker DG, Terai K, Matsuo A, Beach TG, McGeer EG, McGeer PL. Immunohistochemical analyses of fibroblast growth factor receptor-1 in the human substantia nigra. Comparison between normal and Parkinson's disease cases. Brain Research. 794: 181-7. PMID 9622624 DOI: 10.1016/S0006-8993(98)00132-2  0.302
1998 McGeer EG, McGeer PL. The future use of complement inhibitors for the treatment of neurological diseases. Drugs. 55: 739-46. PMID 9617589 DOI: 10.2165/00003495-199855060-00001  0.323
1998 Walker DG, Beach TG, Xu R, Lile J, Beck KD, McGeer EG, McGeer PL. Expression of the proto-oncogene Ret, a component of the GDNF receptor complex, persists in human substantia nigra neurons in Parkinson's disease. Brain Research. 792: 207-17. PMID 9593897 DOI: 10.1016/S0006-8993(98)00131-0  0.34
1997 Wszolek ZK, Vieregge P, Uitti RJ, Gasser T, Yasuhara O, McGeer P, Berry K, Calne DB, Vingerhoets FJ, Klein C, Pfeiffer RF. German-Canadian family (family A) with parkinsonism, amyotrophy, and dementia - Longitudinal observations. Parkinsonism & Related Disorders. 3: 125-39. PMID 18591067 DOI: 10.1016/S1353-8020(97)00013-8  0.341
1997 Shen Y, Li R, McGeer EG, McGeer PL. Neuronal expression of mRNAs for complement proteins of the classical pathway in Alzheimer brain. Brain Research. 769: 391-5. PMID 9374212 DOI: 10.1016/S0006-8993(97)00850-0  0.357
1997 Akiyama H, Mori H, Sahara N, Kondo H, Ikeda K, Nishimura T, Oda T, McGeer PL. Variable deposition of amyloid beta-protein (A beta) with the carboxy-terminus that ends at residue valine40 (A beta 40) in the cerebral cortex of patients with Alzheimer's disease: a double-labeling immunohistochemical study with antibodies specific for A beta 40 and the A beta that ends at residues alanine42/threonine43 (A beta 42). Neurochemical Research. 22: 1499-506. PMID 9357016 DOI: 10.1023/A:1021910729963  0.348
1997 Webster S, Lue LF, Brachova L, Tenner AJ, McGeer PL, Terai K, Walker DG, Bradt B, Cooper NR, Rogers J. Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease. Neurobiology of Aging. 18: 415-21. PMID 9330973 DOI: 10.1016/S0197-4580(97)00042-0  0.403
1997 Klegeris A, McGeer PL. beta-amyloid protein enhances macrophage production of oxygen free radicals and glutamate. Journal of Neuroscience Research. 49: 229-35. PMID 9272645 DOI: 10.1002/(Sici)1097-4547(19970715)49:2<229::Aid-Jnr11>3.0.Co;2-W  0.341
1997 Yasuhara O, Matsuo A, Terai K, Walker DG, Berger AE, Akiguchi I, Kimura J, McGeer PL. Expression of interleukin-1 receptor antagonist protein in post-mortem human brain tissues of Alzheimer's disease and control cases. Acta Neuropathologica. 93: 414-20. PMID 9113207 DOI: 10.1007/S004010050633  0.371
1997 McGeer PL, Walker DG, Pitas RE, Mahley RW, McGeer EG. Apolipoprotein E4 (ApoE4) but not ApoE3 or ApoE2 potentiates beta-amyloid protein activation of complement in vitro. Brain Research. 749: 135-8. PMID 9070638 DOI: 10.1016/S0006-8993(96)01324-8  0.312
1997 Takami K, Terai K, Matsuo A, Walker DG, McGeer PL. Expression of presenilin-1 and -2 mRNAs in rat and Alzheimer's disease brains. Brain Research. 748: 122-30. PMID 9067452 DOI: 10.1016/S0006-8993(96)01274-7  0.375
1997 Klegeris A, Walker DG, McGeer PL. Interaction of Alzheimer beta-amyloid peptide with the human monocytic cell line THP-1 results in a protein kinase C-dependent secretion of tumor necrosis factor-alpha. Brain Research. 747: 114-21. PMID 9042534 DOI: 10.1016/S0006-8993(96)01229-2  0.344
1997 McGeer EG, McGeer PL. Inflammatory Cytokines in the CNS Cns Drugs. 7: 214-228. DOI: 10.2165/00023210-199707030-00005  0.349
1996 Aimi Y, McGeer PL. Lack of toxicity of human neuromelanin to rat brain dopaminergic neurons. Parkinsonism & Related Disorders. 2: 69-74. PMID 18591021 DOI: 10.1016/1353-8020(96)00004-1  0.337
1996 Matsuo A, Walker DG, Terai K, McGeer PL. Expression of CD43 in human microglia and its downregulation in Alzheimer's disease. Journal of Neuroimmunology. 71: 81-6. PMID 8982106 DOI: 10.1016/S0165-5728(96)00134-8  0.35
1996 Akiyama H, Kondo H, Mori H, Kametani F, Nishimura T, Ikeda K, Kato M, McGeer PL. The amino-terminally truncated forms of amyloid beta-protein in brain macrophages in the ischemic lesions of Alzheimer's disease patients. Neuroscience Letters. 219: 115-8. PMID 8971793 DOI: 10.1016/S0304-3940(96)13197-9  0.388
1996 Terai K, Matsuo A, McGeer EG, McGeer PL. Enhancement of immunoreactivity for NF-kappa B in human cerebral infarctions. Brain Research. 739: 343-9. PMID 8955958 DOI: 10.1016/S0006-8993(96)01073-6  0.315
1996 Schwab C, Steele JC, McGeer PL. Neurofibrillary tangles of Guam parkinson-dementia are associated with reactive microglia and complement proteins. Brain Research. 707: 196-205. PMID 8919296 DOI: 10.1016/0006-8993(95)01257-5  0.37
1996 Yasuhara O, Schwab C, Matsuo A, Kim SU, Steele JC, Akiguchi I, Kimura J, McGeer EG, McGeer PL. Midkine-like immunoreactivity in extracellular neurofibrillary tangles in brains of patients with parkinsonism-dementia complex of Guam. Neuroscience Letters. 205: 107-10. PMID 8907328 DOI: 10.1016/0304-3940(96)12385-5  0.4
1996 Terai K, Matsuo A, McGeer PL. Enhancement of immunoreactivity for NF-kappa B in the hippocampal formation and cerebral cortex of Alzheimer's disease. Brain Research. 735: 159-68. PMID 8905182 DOI: 10.1016/0006-8993(96)00310-1  0.355
1996 Rogers J, Webster S, Lue LF, Brachova L, Civin WH, Emmerling M, Shivers B, Walker D, McGeer P. Inflammation and Alzheimer's disease pathogenesis. Neurobiology of Aging. 17: 681-6. PMID 8892340 DOI: 10.1016/0197-4580(96)00115-7  0.379
1996 Schwab C, Steele JC, Akiyama H, McGeer PL. Distinct distribution of apolipoprotein E and beta-amyloid immunoreactivity in the hippocampus of Parkinson dementia complex of Guam. Acta Neuropathologica. 92: 378-85. PMID 8891070 DOI: 10.1007/S004010050533  0.37
1996 McGeer PL, Schulzer M, McGeer EG. Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies. Neurology. 47: 425-32. PMID 8757015 DOI: 10.1212/Wnl.47.2.425  0.326
1996 Yasuhara O, Akiguchi I, Nakamura S, Kinoshita A, Ikemoto A, Kawamoto Y, Kimura J, Funakoshi A, Tateishi K, McGeer PL. Pancreastatin-like immunoreactivity in globular dystrophic neurites of senile plaques in brains of patients with Alzheimer's disease. Neuroscience Letters. 208: 167-70. PMID 8733296 DOI: 10.1016/0304-3940(96)12573-8  0.407
1996 Akiyama H, Schwab C, Kondo H, Mori H, Kametani F, Ikeda K, McGeer PL. Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of beta-amyloid protein. Neuroscience Letters. 206: 169-72. PMID 8710178 DOI: 10.1016/S0304-3940(96)12474-5  0.378
1996 Jefferies WA, Food MR, Gabathuler R, Rothenberger S, Yamada T, Yasuhara O, McGeer PL. Reactive microglia specifically associated with amyloid plaques in Alzheimer's disease brain tissue express melanotransferrin. Brain Research. 712: 122-6. PMID 8705294 DOI: 10.1016/0006-8993(95)01407-1  0.368
1996 Rothenberger S, Food MR, Gabathuler R, Kennard ML, Yamada T, Yasuhara O, McGeer PL, Jefferies WA. Coincident expression and distribution of melanotransferrin and transferrin receptor in human brain capillary endothelium. Brain Research. 712: 117-21. PMID 8705293 DOI: 10.1016/0006-8993(96)88505-2  0.301
1996 Oken RJ, McGeer PL. Schizophrenia, Alzheimer's disease, and anti-inflammatory agents. Schizophrenia Bulletin. 22: 1-4. PMID 8685652 DOI: 10.1093/Schbul/22.1.1  0.304
1996 McGeer PL, McGeer EG. Anti-inflammatory drugs in the fight against Alzheimer's disease. Annals of the New York Academy of Sciences. 777: 213-20. PMID 8624086 DOI: 10.1111/J.1749-6632.1996.Tb34421.X  0.38
1996 McGeer P, Schulzer M, McGeer E. 807 Evidence supporting the inflammatory hypothesis of Alzheimer disease Neurobiology of Aging. 17: S201. DOI: 10.1016/S0197-4580(96)80809-8  0.348
1996 Kawamata T, Hashimoto T, Taniguchi T, Niu S, Nakai M, Yasuda M, Tcrashima A, Macda K, Nishimura A, Tatsuno Y, Akiguchi I, McGeer P, Tanaka C. 547 Presenilin-1 (S182) immunobistochemistry in Alzheimer brain tissues Neurobiology of Aging. 17: S136. DOI: 10.1016/S0197-4580(96)80549-5  0.332
1996 Akiyama H, Schwab C, Kondo H, Mori H, Kametani F, Ikeda K, McGeer PL. 419 Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of β-amyloid protein Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80421-0  0.333
1996 Takami K, Walker D, McGeer P. 71 Expression of presenilin-1 and -2 mRNAs in rat and Alzheimer brains Neurobiology of Aging. 17: S18. DOI: 10.1016/S0197-4580(96)80073-X  0.313
1995 Uitti RJ, Berry K, Yasuhara O, Eisen A, Feldman H, McGeer PL, Calne DB. Neurodegenerative 'overlap' syndrome: Clinical and pathological features of Parkinson's disease, motor neuron disease, and Alzheimer's disease. Parkinsonism & Related Disorders. 1: 21-34. PMID 18590998 DOI: 10.1016/1353-8020(95)00004-P  0.341
1995 McGeer PL, McGeer EG. The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Research. Brain Research Reviews. 21: 195-218. PMID 8866675 DOI: 10.1016/0165-0173(95)00011-9  0.395
1995 Tooyama I, Kawamata T, Akiyama H, Kimura H, Moestrup SK, Gliemann J, Matsuo A, McGeer PL. Subcellular localization of the low density lipoprotein receptor-related protein (alpha 2-macroglobulin receptor) in human brain. Brain Research. 691: 235-8. PMID 8590059 DOI: 10.1016/0006-8993(95)00735-9  0.31
1995 Schwab C, Steele JC, Akiyama H, McGeer EG, McGeer PL. Relationship of amyloid beta/A4 protein to the neurofibrillary tangles in Guamanian parkinsonism-dementia. Acta Neuropathologica. 90: 287-98. PMID 8525803 DOI: 10.1007/Bf00296513  0.381
1995 Oken RJ, McGeer PL. Down's syndrome: prophylaxis and therapy for the frequently comorbid Alzheimer's disease. Medical Hypotheses. 44: 233-4. PMID 7666820 DOI: 10.1016/0306-9877(95)90170-1  0.364
1995 Walker DG, Kim SU, McGeer PL. Complement and cytokine gene expression in cultured microglial derived from postmortem human brains. Journal of Neuroscience Research. 40: 478-93. PMID 7616608 DOI: 10.1002/Jnr.490400407  0.306
1995 Yasuhara O, Matsuo A, Tooyama I, Kimura H, McGeer EG, McGeer PL. Pick's disease immunohistochemistry: new alterations and Alzheimer's disease comparisons. Acta Neuropathologica. 89: 322-30. PMID 7610763 DOI: 10.1007/Bf00309625  0.394
1995 Oken RJ, McGeer PL. Human prion diseases: possible new directions in prophylaxis and therapy. Medical Hypotheses. 44: 167-8. PMID 7609669 DOI: 10.1016/0306-9877(95)90130-2  0.418
1994 Yasuhara O, Akiyama H, McGeer EG, McGeer PL. Immunohistochemical localization of hyaluronic acid in rat and human brain. Brain Research. 635: 269-82. PMID 8173963 DOI: 10.1016/0006-8993(94)91448-6  0.348
1994 Akiyama H, Tooyama I, Kondo H, Ikeda K, Kimura H, McGeer EG, McGeer PL. Early response of brain resident microglia to kainic acid-induced hippocampal lesions. Brain Research. 635: 257-68. PMID 8173962 DOI: 10.1016/0006-8993(94)91447-8  0.332
1994 Akiyama H, Ikeda K, Katoh M, McGeer EG, McGeer PL. Expression of MRP14, 27E10, interferon-alpha and leukocyte common antigen by reactive microglia in postmortem human brain tissue. Journal of Neuroimmunology. 50: 195-201. PMID 8120141 DOI: 10.1016/0165-5728(94)90046-9  0.38
1994 Yasuhara O, Kawamata T, Aimi Y, McGeer EG, McGeer PL. Two types of dystrophic neurites in senile plaques of Alzheimer disease and elderly non-demented cases. Neuroscience Letters. 171: 73-6. PMID 8084503 DOI: 10.1016/0304-3940(94)90608-4  0.34
1994 Yasuhara O, Aimi Y, McGeer EG, McGeer PL. Accumulation of amyloid precursor protein in brain lesions of patients with Pick disease. Neuroscience Letters. 171: 63-6. PMID 8084502 DOI: 10.1016/0304-3940(94)90605-X  0.369
1994 Itagaki S, Akiyama H, Saito H, McGeer PL. Ultrastructural localization of complement membrane attack complex (MAC)-like immunoreactivity in brains of patients with Alzheimer's disease. Brain Research. 645: 78-84. PMID 8062101 DOI: 10.1016/0006-8993(94)91640-3  0.374
1994 Yasuhara O, Kawamata T, Aimi Y, McGeer EG, McGeer PL. Expression of chromogranin A in lesions in the central nervous system from patients with neurological diseases. Neuroscience Letters. 170: 13-6. PMID 8041489 DOI: 10.1016/0304-3940(94)90227-5  0.389
1994 Moroo I, Yamada T, Makino H, Tooyama I, McGeer PL, McGeer EG, Hirayama K. Loss of insulin receptor immunoreactivity from the substantia nigra pars compacta neurons in Parkinson's disease. Acta Neuropathologica. 87: 343-8. PMID 8017169 DOI: 10.1007/Bf00313602  0.334
1994 Yasuhara O, Walker DG, McGeer PL. Hageman factor and its binding sites are present in senile plaques of Alzheimer's disease. Brain Research. 654: 234-40. PMID 7987673 DOI: 10.1016/0006-8993(94)90484-7  0.366
1994 McGeer PL, Rogers J, McGeer EG. Neuroimmune mechanisms in Alzheimer disease pathogenesis. Alzheimer Disease and Associated Disorders. 8: 149-58. PMID 7986484 DOI: 10.1097/00002093-199408030-00001  0.352
1994 Tooyama I, McGeer EG, Kawamata T, Kimura H, McGeer PL. Retention of basic fibroblast growth factor immunoreactivity in dopaminergic neurons of the substantia nigra during normal aging in humans contrasts with loss in Parkinson's disease. Brain Research. 656: 165-8. PMID 7804831 DOI: 10.1016/0006-8993(94)91378-1  0.319
1994 McGeer PL, Klegeris A, Walker DG, Yasuhara O, McGeer EG. Pathological proteins in senile plaques. The Tohoku Journal of Experimental Medicine. 174: 269-77. PMID 7761992 DOI: 10.1620/Tjem.174.269  0.353
1994 Kimura H, Tooyama I, McGeer PL. Acidic FGF expression in the surroundings of senile plaques. The Tohoku Journal of Experimental Medicine. 174: 279-93. PMID 7539161 DOI: 10.1620/Tjem.174.279  0.381
1994 Hara Y, Tooyama I, Yasuhara O, Akiyama H, McGeer PL, Handa J, Kimura H. Acidic fibroblast growth factor-like immunoreactivity in rat brain following cerebral infarction. Brain Research. 664: 101-7. PMID 7534599 DOI: 10.1016/0006-8993(94)91959-3  0.306
1994 Yasuhara O, Aimi Y, McGeer EG, McGeer PL. Expression of the complement membrane attack complex and its inhibitors in Pick disease brain. Brain Research. 652: 346-9. PMID 7525023 DOI: 10.1016/0006-8993(94)90246-1  0.362
1994 Akiyama H, Nishimura T, Kondo H, Ikeda K, Hayashi Y, McGeer PL. Expression of the receptor for macrophage colony stimulating factor by brain microglia and its upregulation in brains of patients with Alzheimer's disease and amyotrophic lateral sclerosis. Brain Research. 639: 171-4. PMID 7514086 DOI: 10.1016/0006-8993(94)91779-5  0.36
1993 Tooyama I, Kawamata T, Akiyama H, Moestrup SK, Gliemann J, McGeer PL. Immunohistochemical study of alpha 2 macroglobulin receptor in Alzheimer and control postmortem human brain. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 18: 153-60. PMID 8466589 DOI: 10.1007/Bf03160029  0.395
1993 Mizukawa K, McGeer EG, McGeer PL. Autoradiographic study on dopamine uptake sites and their correlation with dopamine levels and their striata from patients with Parkinson disease, Alzheimer disease, and neurologically normal controls. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 18: 133-44. PMID 8466587 DOI: 10.1007/Bf03160027  0.303
1993 McGeer PL, Kawamata T, Walker DG, Akiyama H, Tooyama I, McGeer EG. Microglia in degenerative neurological disease. Glia. 7: 84-92. PMID 8423066 DOI: 10.1002/Glia.440070114  0.386
1993 Akiyama H, Kawamata T, Yamada T, Tooyama I, Ishii T, McGeer PL. Expression of intercellular adhesion molecule (ICAM)-1 by a subset of astrocytes in Alzheimer disease and some other degenerative neurological disorders. Acta Neuropathologica. 85: 628-34. PMID 8337942 DOI: 10.1007/Bf00334673  0.408
1993 Yasuhara O, Hanai K, Ohkubo I, Sasaki M, McGeer PL, Kimura H. Expression of cystatin C in rat, monkey and human brains. Brain Research. 628: 85-92. PMID 8313175 DOI: 10.1016/0006-8993(93)90941-F  0.341
1993 Akiyama H, Ikeda K, Kondo H, Kato M, McGeer PL. Microglia express the type 2 plasminogen activator inhibitor in the brain of control subjects and patients with Alzheimer's disease. Neuroscience Letters. 164: 233-5. PMID 8152607 DOI: 10.1016/0304-3940(93)90899-V  0.395
1993 Tooyama I, Kremer HP, Hayden MR, Kimura H, McGeer EG, McGeer PL. Acidic and basic fibroblast growth factor-like immunoreactivity in the striatum and midbrain in Huntington's disease. Brain Research. 610: 1-7. PMID 7686078 DOI: 10.1016/0006-8993(93)91209-B  0.346
1993 Akiyama H, Tooyama I, Kawamata T, Ikeda K, McGeer PL. Morphological diversities of CD44 positive astrocytes in the cerebral cortex of normal subjects and patients with Alzheimer's disease. Brain Research. 632: 249-59. PMID 7511977 DOI: 10.1016/0006-8993(93)91160-T  0.306
1992 McGeer PL, Rogers J. Anti-inflammatory agents as a therapeutic approach to Alzheimer's disease. Neurology. 42: 447-9. PMID 1736183 DOI: 10.1212/Wnl.42.2.447  0.383
1992 Akiyama H, Ikeda K, Kondo H, McGeer PL. Thrombin accumulation in brains of patients with Alzheimer's disease. Neuroscience Letters. 146: 152-4. PMID 1491781 DOI: 10.1016/0304-3940(92)90065-F  0.393
1992 Shigematsu K, McGeer PL. Accumulation of amyloid precursor protein in damaged neuronal processes and microglia following intracerebral administration of aluminum salts. Brain Research. 593: 117-23. PMID 1458313 DOI: 10.1016/0006-8993(92)91272-G  0.388
1992 Tooyama I, Walker D, Yamada T, Hanai K, Kimura H, McGeer EG, McGeer PL. High molecular weight basic fibroblast growth factor-like protein is localized to a subpopulation of mesencephalic dopaminergic neurons in the rat brain. Brain Research. 593: 274-80. PMID 1450935 DOI: 10.1016/0006-8993(92)91318-9  0.304
1992 Rogers J, Cooper NR, Webster S, Schultz J, McGeer PL, Styren SD, Civin WH, Brachova L, Bradt B, Ward P. Complement activation by beta-amyloid in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 89: 10016-20. PMID 1438191 DOI: 10.1073/Pnas.89.21.10016  0.339
1992 Walker DG, McGeer PL. Complement gene expression in human brain: comparison between normal and Alzheimer disease cases. Brain Research. Molecular Brain Research. 14: 109-16. PMID 1323007 DOI: 10.1016/0169-328X(92)90017-6  0.353
1992 Tooyama I, Yamada T, Kim SU, McGeer PL. Immunohistochemical study of A2B5-positive ganglioside in postmortem human brain tissue of Alzheimer disease, amyotrophic lateral sclerosis, progressive supranuclear palsy and control cases. Neuroscience Letters. 136: 91-4. PMID 1321969 DOI: 10.1016/0304-3940(92)90655-Q  0.348
1992 Yamada T, McGeer PL, McGeer EG. Some immunohistochemical features of argyrophilic grain dementia with normal cortical choline acetyltransferase levels but extensive subcortical pathology and markedly reduced dopamine. Journal of Geriatric Psychiatry and Neurology. 5: 3-13. PMID 1315137 DOI: 10.1177/002383099200500102  0.348
1992 Tago H, Maeda T, McGeer PL, Kimura H. Butyrylcholinesterase-rich neurons in rat brain demonstrated by a sensitive histochemical method. The Journal of Comparative Neurology. 325: 301-12. PMID 1281176 DOI: 10.1002/Cne.903250212  0.308
1992 Shigematsu K, McGeer PL, McGeer EG. Localization of amyloid precursor protein in selective postsynaptic densities of rat cortical neurons. Brain Research. 592: 353-7. PMID 1280522 DOI: 10.1016/0006-8993(92)91697-D  0.317
1992 McGeer PL. The pivotal role of microglia in the pathology of Alzheimer's disease Journal of Neuroimmunology. 40: 132. DOI: 10.1016/0165-5728(92)90243-E  0.366
1991 Yamada T, McGeer PL, Baimbridge KG, McGeer EG. Relative sparing in Parkinson's disease of substantia nigra dopamine neurons containing calbindin-D28K. Brain Research. 526: 303-7. PMID 2257487 DOI: 10.1016/0006-8993(90)91236-A  0.326
1991 Yamada T, Akiyama H, McGeer PL. Two types of spheroid bodies in the nigral neurons in Parkinson's disease. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 18: 287-94. PMID 1913362 DOI: 10.1017/S0317167100031838  0.34
1991 Akiyama H, Yamada T, Kawamata T, McGeer PL. Association of amyloid P component with complement proteins in neurologically diseased brain tissue. Brain Research. 548: 349-52. PMID 1831062 DOI: 10.1016/0006-8993(91)91148-T  0.35
1991 McGeer PL, Walker DG, Akiyama H, Kawamata T, Guan AL, Parker CJ, Okada N, McGeer EG. Detection of the membrane inhibitor of reactive lysis (CD59) in diseased neurons of Alzheimer brain. Brain Research. 544: 315-9. PMID 1710165 DOI: 10.1016/0006-8993(91)90071-3  0.383
1991 Yasuhara O, Tooyama I, Akiyama H, Akiguchi I, Kimura J, McGeer PL, Hara Y, Kimura H. Reactive Astrocytes Express Acidic Fibroblast Growth Factor in Alzheimer's Disease Brain Dementia and Geriatric Cognitive Disorders. 2: 64-70. DOI: 10.1159/000107178  0.373
1990 McGeer PL, McGeer EG. Cholinergic enzyme systems in Parkinson's disease. Archives of Neurology. 25: 265-8. PMID 4157296 DOI: 10.1001/Archneur.1971.00490030091011  0.348
1990 Tooyama I, Kimura H, Akiyama H, McGeer PL. Reactive microglia express class I and class II major histocompatibility complex antigens in Alzheimer's disease. Brain Research. 523: 273-80. PMID 2400911 DOI: 10.1016/0006-8993(90)91496-4  0.322
1990 Akiyama H, Kaneko T, Mizuno N, McGeer PL. Distribution of phosphate-activated glutaminase in the human cerebral cortex Journal of Comparative Neurology. 297: 239-252. PMID 2196285 DOI: 10.1002/Cne.902970207  0.319
1990 Akiyama H, McGeer PL. Brain microglia constitutively express β-2 integrins Journal of Neuroimmunology. 30: 81-93. PMID 1977769 DOI: 10.1016/0165-5728(90)90055-R  0.355
1990 Zhu SG, McGeer EG, McGeer PL. gamma-Glutamyltransferase activity is unchanged in acutely quinolinate-lesioned rat neostriatum but is elevated in Huntington's disease caudate. Experimental Neurology. 107: 106-9. PMID 1967236 DOI: 10.1016/0014-4886(90)90067-3  0.331
1989 McGeer PL, Itagaki S, Akiyama H, McGeer EG. Rate of cell death in parkinsonism indicates active neuropathological process. Annals of Neurology. 24: 574-6. PMID 3239957 DOI: 10.1002/Ana.410240415  0.335
1989 McGeer PL, Itagaki S, Tago H, McGeer EG. Occurrence of HLA-DR reactive microglia in Alzheimer's disease. Annals of the New York Academy of Sciences. 540: 319-23. PMID 3061340 DOI: 10.1111/J.1749-6632.1988.Tb27086.X  0.342
1989 McGeer EG, Singh EA, McGeer PL. Peripheral-type benzodiazepine binding in Alzheimer disease. Alzheimer Disease and Associated Disorders. 2: 331-6. PMID 2848549 DOI: 10.1097/00002093-198802040-00001  0.346
1989 Itagaki S, McGeer PL, Akiyama H, Zhu S, Selkoe D. Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease. Journal of Neuroimmunology. 24: 173-182. PMID 2808689 DOI: 10.1016/0165-5728(89)90115-X  0.346
1988 McGeer PL, McGeer EG, Itagaki S, Mizukawa K. Anatomy and pathology of the basal ganglia. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 14: 363-72. PMID 2890425 DOI: 10.1017/S0317167100037756  0.362
1987 McGeer PL, Itagaki S, Tago H, McGeer EG. Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR. Neuroscience Letters. 79: 195-200. PMID 3670729 DOI: 10.1016/0304-3940(87)90696-3  0.328
1987 McGeer PL, McGeer EG, Kamo H, Wong K. Positron emission tomography and the possible origins of cytopathology in Alzheimer's disease. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 10: 501-18. PMID 3541048 DOI: 10.1016/0278-5846(86)90021-7  0.359
1987 Tago H, McGeer PL, Bruce G, Hersh LB. Distribution of choline acetyltransferase-containing neurons of the hypothalamus. Brain Research. 415: 49-62. PMID 3304532 DOI: 10.1016/0006-8993(87)90268-X  0.307
1987 McGeer EG, Singh EA, McGeer PL. Sodium-dependent glutamate binding in senile dementia. Neurobiology of Aging. 8: 219-23. PMID 2885768 DOI: 10.1016/0197-4580(87)90005-4  0.317
1987 Beach TG, Tago H, Nagai T, Kimura H, McGeer PL, McGeer EG. Perfusion-fixation of the human brain for immunohistochemistry: comparison with immersion-fixation. Journal of Neuroscience Methods. 19: 183-92. PMID 2437408 DOI: 10.1016/S0165-0270(87)80001-8  0.319
1987 McGeer EG, Singh EA, McGeer PL. γ-GLUTAMYLTRANSFERASE Alzheimer Disease & Associated Disorders. 1: 38-42. DOI: 10.1097/00002093-198701000-00005  0.333
1986 McGeer E, McGeer PL. Possible destruction of cholinoceptive neurons by overstimulation of cholinergic tracts. Canadian Journal of Physiology and Pharmacology. 64: 363-8. PMID 2871914 DOI: 10.1139/Y86-059  0.315
1983 Nagai T, McGeer PL, Peng JH, McGeer EG, Dolman CE. Choline acetyltransferase immunohistochemistry in brains of Alzheimer's disease patients and controls. Neuroscience Letters. 36: 195-9. PMID 6866327 DOI: 10.1016/0304-3940(83)90264-1  0.372
1982 Peng JH, McGeer PL, McGeer EG. Cross-reactivity of antibodies to chicken brain choline acetyltransferase with mammalian enzyme. Journal of Neuroimmunology. 3: 113-21. PMID 6811613 DOI: 10.1016/0165-5728(82)90045-5  0.301
1982 Wong PT, McGeer PL, Rossor M, McGeer EG. Ornithine aminotransferase in Huntington's disease. Brain Research. 231: 466-71. PMID 6459816 DOI: 10.1016/0006-8993(82)90385-7  0.349
1980 Kimura H, McGeer PL, Peng F, McGeer EG. Choline acetyltransferase-containing neurons in rodent brain demonstrated by immunohistochemistry. Science (New York, N.Y.). 208: 1057-9. PMID 6990490 DOI: 10.1126/Science.6990490  0.312
1971 McGeer PL, McGeer EG, Wada JA, Jung E. Effects of globus pallidus lesions and Parkinson's disease on brain glutamic acid decarboxylase. Brain Research. 32: 425-31. PMID 4944072 DOI: 10.1016/0006-8993(71)90334-9  0.317
1967 McGeer EG, Gibson S, McGeer PL. Some Characteristics Of Brain Tyrosine Hydroxylase Biochemistry and Cell Biology. 45: 53-68. DOI: 10.1007/978-1-4613-4574-9_4  0.319
1963 McGeer E, Ling G, McGeer P. Conversion of tyrosine to catecholamines by cat brain in vivo Biochemical and Biophysical Research Communications. 13: 291-296. DOI: 10.1016/0006-291X(63)90487-X  0.302
1956 Rathmann GB, Curtis AJ, Mcgeer PL, Smyth CP. Microwave absorption and molecular structure in liquids. XIII. The critical wavelengths of some aliphatic ethers and long-chain ketones The Journal of Chemical Physics. 25: 413-416. DOI: 10.1063/1.1742936  0.706
1952 Curtis AJ, McGeer PL, Rathmann GB, Smyth CP. Microwave Absorption and Molecular Structure in Liquids. VII. Effects of Viscosity and Dipole—Dipole Forces1 Journal of the American Chemical Society. 74: 644-648. DOI: 10.1021/Ja01123A018  0.414
Low-probability matches (unlikely to be authored by this person)
2014 McGeer PL. Effective strategies for translating basic research into clinical success in Alzheimer's disease. Bmj (Clinical Research Ed.). 348: g1853. PMID 24603570 DOI: 10.1136/Bmj.G1853  0.3
2002 Klegeris A, Singh EA, McGeer PL. Effects of C-reactive protein and pentosan polysulphate on human complement activation. Immunology. 106: 381-8. PMID 12100726 DOI: 10.1046/J.1365-2567.2002.01425.X  0.298
1989 McGeer EG, McGeer PL. Effect of fixatives on rat brain acetylcholinesterase activity. Journal of Neuroscience Methods. 28: 235-7. PMID 2755181 DOI: 10.1016/0165-0270(89)90042-3  0.298
1993 Walker DG, McGeer PL. Complement gene expression in neuroblastoma and astrocytoma cell lines of human origin. Neuroscience Letters. 157: 99-102. PMID 8233040 DOI: 10.1016/0304-3940(93)90652-2  0.297
1969 Poirier LJ, McGeer EG, Larochelle L, McGeer PL, Bedard P, Boucher R. The effect of brain stem lesions on tyrosine and tryptophan hydroxylases in various structures of the telencephalon of the cat. Brain Research. 14: 147-55. PMID 5783106 DOI: 10.1016/0006-8993(69)90036-5  0.297
2006 Klegeris A, Giasson BI, Zhang H, Maguire J, Pelech S, McGeer PL. Alpha-synuclein and its disease-causing mutants induce ICAM-1 and IL-6 in human astrocytes and astrocytoma cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2000-8. PMID 17012252 DOI: 10.1096/Fj.06-6183Com  0.296
1984 McGeer EG, Staines WA, McGeer PL. Neurotransmitters in the basal ganglia. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 11: 89-99. PMID 6143612 DOI: 10.1017/S0317167100046217  0.295
1972 Jakubovic A, McGeer PL. Inhibition of rat brain protein and nucleic acid synthesis by cannabinoids in vitro. Canadian Journal of Biochemistry. 50: 654-62. PMID 5042874 DOI: 10.1139/O72-090  0.295
2001 Yasojima K, Schwab C, McGeer EG, McGeer PL. Generation of C-reactive protein and complement components in atherosclerotic plaques. The American Journal of Pathology. 158: 1039-51. PMID 11238052 DOI: 10.1016/S0002-9440(10)64051-5  0.295
1987 Kamo H, Haebara H, Akiguchi I, Kameyama M, Kimura H, McGeer PL. A distinctive distribution of reactive astroglia in the precentral cortex in amyotrophic lateral sclerosis. Acta Neuropathologica. 74: 33-38. PMID 3310502 DOI: 10.1007/Bf00688335  0.295
1999 Pérez-Tur J, Buée L, Morris HR, Waring SC, Onstead L, Wavrant-De Vrièze F, Crook R, Buée-Scherrer V, Hof PR, Petersen RC, McGeer PL, Delacourte A, Hutton M, Siddique T, Ahlskog JE, et al. Neurodegenerative diseases of Guam: analysis of TAU. Neurology. 53: 411-3. PMID 10430438 DOI: 10.1212/Wnl.53.2.411  0.295
2011 Hashioka S, Klegeris A, Qing H, McGeer PL. STAT3 inhibitors attenuate interferon-γ-induced neurotoxicity and inflammatory molecule production by human astrocytes. Neurobiology of Disease. 41: 299-307. PMID 20888416 DOI: 10.1016/J.Nbd.2010.09.018  0.294
2020 McGeer PL, Lee M, Kennedy K, McGeer EG. Saliva Diagnosis as a Disease Predictor. Journal of Clinical Medicine. 9. PMID 32019214 DOI: 10.3390/Jcm9020377  0.293
2009 McGeer PL, Tobinick E, Kornelsen R, McCormick S, Ferreira C, Lapi S, Ruth TJ. WITHDRAWN: PET Imaging Reveals that Etanercept Crosses the Blood-Cerebrospinal Fluid but not the Blood-Brain Barrier: Implications for Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 19433894 DOI: 10.3233/Jad-2009-1081  0.293
1992 Boyes BE, Walker DG, McGeer PL, McGeer EG. Identification and characterization of a large human brain gene whose expression is increased in Alzheimer disease. Brain Research. Molecular Brain Research. 12: 47-57. PMID 1372073 DOI: 10.1016/0169-328X(92)90067-L  0.292
1981 Peng JH, Kimura H, McGeer PL, McGeer EG. Anti-choline acetyltransferase fragments antigen binding (Fab) for immunohistochemistry. Neuroscience Letters. 21: 281-5. PMID 7012696 DOI: 10.1016/0304-3940(81)90217-2  0.291
1991 Kimura H, Tago H, Akiyama H, Hersh LB, Tooyama I, McGeer PL. Choline acetyltransferase immunopositive neurons in the lateral septum. Brain Research. 533: 165-70. PMID 2085729 DOI: 10.1016/0006-8993(90)91812-U  0.291
1989 Akiyama H, McGeer PL. Microglial response to 6-hydroxydopamine-induced substantia nigra lesions. Brain Research. 489: 247-53. PMID 2501002 DOI: 10.1016/0006-8993(89)90857-3  0.291
1988 Akiyama H, Itagaki S, McGeer PL. Major histocompatibility complex antigen expression on rat microglia following epidural kainic acid lesions. Journal of Neuroscience Research. 20: 147-57. PMID 3172275 DOI: 10.1002/Jnr.490200202  0.29
2008 Yuan J, Dong Z, Guo JP, McGeehan J, Xiao X, Wang J, Cali I, McGeer PL, Cashman NR, Bessen R, Surewicz WK, Kneale G, Petersen RB, Gambetti P, Zou WQ. Accessibility of a critical prion protein region involved in strain recognition and its implications for the early detection of prions. Cellular and Molecular Life Sciences : Cmls. 65: 631-43. PMID 18193391 DOI: 10.1007/S00018-007-7478-Z  0.289
2002 McGeer PL, Yasojima K, McGeer EG. Association of interleukin-1 beta polymorphisms with idiopathic Parkinson's disease. Neuroscience Letters. 326: 67-9. PMID 12052540 DOI: 10.1016/S0304-3940(02)00300-2  0.289
1989 Mizukawa K, Vincent SR, McGeer PL, McGeer EG. Distribution of reduced-nicotinamide-adenine-dinucleotide-phosphate diaphorase-positive cells and fibers in the cat central nervous system. The Journal of Comparative Neurology. 279: 281-311. PMID 2913070 DOI: 10.1002/Cne.902790210  0.289
2016 Xu Y, Zhang Y, Quan Z, Wong W, Guo J, Zhang R, Yang Q, Dai R, McGeer PL, Qing H. Epigallocatechin Gallate (EGCG) Inhibits Alpha-Synuclein Aggregation: A Potential Agent for Parkinson's Disease. Neurochemical Research. PMID 27364962 DOI: 10.1007/S11064-016-1995-9  0.289
2003 Hosokawa M, Klegeris A, Maguire J, McGeer PL. Expression of complement messenger RNAs and proteins by human oligodendroglial cells. Glia. 42: 417-23. PMID 12730962 DOI: 10.1002/Glia.10234  0.288
1990 McGeer PL, Zhu SG, Dedhar S. Immunostaining of human brain capillaries by antibodies to very late antigens. Journal of Neuroimmunology. 26: 213-8. PMID 1689743 DOI: 10.1016/0165-5728(90)90003-6  0.288
1997 Klegeris A, Walker DG, McGeer PL. Regulation of glutamate in cultures of human monocytic THP-1 and astrocytoma U-373 MG cells. Journal of Neuroimmunology. 78: 152-61. PMID 9307240 DOI: 10.1016/S0165-5728(97)00094-5  0.287
1980 Peng JH, McGeer PL, Kimura H, Sung SC, McGeer EG. Purification and immunochemical properties of choline acetyltransferase from human brain. Neurochemical Research. 5: 943-962. PMID 7207697 DOI: 10.1007/Bf00966135  0.287
1997 Aimi Y, Wakabayashi Y, Yasuhara O, Matsuo A, Kwok YN, McGeer PL, Kimura H. Immunohistochemical localization of low-affinity nerve growth factor receptor in the enteric nervous system of adult rats. The Histochemical Journal. 29: 529-37. PMID 9279555 DOI: 10.1023/A:1026419808286  0.287
2010 Liu J, Shi M, Hong Z, Zhang J, Bradner J, Quinn T, Beyer RP, Mcgeer PL, Chen S, Zhang J. Identification of ciliary neurotrophic factor receptor alpha as a mediator of neurotoxicity induced by alpha-synuclein. Proteomics. 10: 2138-50. PMID 20340160 DOI: 10.1002/Pmic.200900745  0.286
2002 McGeer PL, McGeer EG, Yasojima K. Expression of COX-1 and COX-2 mRNAs in atherosclerotic plaques. Experimental Gerontology. 37: 925-9. PMID 12086701 DOI: 10.1016/S0531-5565(02)00028-1  0.286
2008 Klegeris A, Pelech S, Giasson BI, Maguire J, Zhang H, McGeer EG, McGeer PL. Alpha-synuclein activates stress signaling protein kinases in THP-1 cells and microglia. Neurobiology of Aging. 29: 739-52. PMID 17166628 DOI: 10.1016/J.Neurobiolaging.2006.11.013  0.286
1993 Yasuhara O, Muramatsu H, Kim SU, Muramatsu T, Maruta H, McGeer PL. Midkine, a novel neurotrophic factor, is present in senile plaques of Alzheimer disease. Biochemical and Biophysical Research Communications. 192: 246-51. PMID 8476427 DOI: 10.1006/bbrc.1993.1406  0.285
1968 McGeer EG, McGeer PL, Peters DA. Inhibition of brain tyrosine hydroxylase by 5-halotryptophans. Life Sciences. 6: 2221-32. PMID 6061008 DOI: 10.1016/0024-3205(67)90246-9  0.285
1987 Mizukawa K, McGeer PL, Vincent SR, McGeer EG. The distribution of somatostatin-immunoreactive neurons and fibers in the rat cerebral cortex: light and electron microscopic studies. Brain Research. 426: 28-36. PMID 2891408 DOI: 10.1016/0006-8993(87)90421-5  0.285
1963 Iyer NT, McGeer PL, McGeer EG. CONVERSION OF TYROSINE TO CATECHOLAMINES BY RAT BRAIN SLICES Canadian Journal of Biochemistry and Physiology. 41: 1565-1570. DOI: 10.1139/O63-178  0.284
1998 Matsuo A, Akiguchi I, Lee GC, McGeer EG, McGeer PL, Kimura J. Myelin degeneration in multiple system atrophy detected by unique antibodies. The American Journal of Pathology. 153: 735-44. PMID 9736024 DOI: 10.1016/S0002-9440(10)65617-9  0.284
1977 McGeer PL, McGeer EG, Suzuki JS. Aging and extrapyramidal function. Archives of Neurology. 34: 33-5. PMID 12731 DOI: 10.1001/Archneur.1977.00500130053010  0.284
2015 Zhao T, Gao J, Van J, To E, Wang A, Cao S, Cui JZ, Guo JP, Lee M, McGeer PL, Matsubara JA. Age-related increases in amyloid beta and membrane attack complex: evidence of inflammasome activation in the rodent eye. Journal of Neuroinflammation. 12: 121. PMID 26104676 DOI: 10.1186/S12974-015-0337-1  0.284
1993 Kawamata T, Tooyama I, Yamada T, Walker DG, McGeer PL. Lactotransferrin immunocytochemistry in Alzheimer and normal human brain. The American Journal of Pathology. 142: 1574-85. PMID 8494052  0.283
2003 Klegeris A, Bissonnette CJ, McGeer PL. Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor. British Journal of Pharmacology. 139: 775-86. PMID 12813001 DOI: 10.1038/Sj.Bjp.0705304  0.282
1983 Wong PT, McGeer EG, McGeer PL. Effects of kainic acid injection and cortical lesion on ornithine and aspartate aminotransferases in rat striatum. Journal of Neuroscience Research. 8: 643-50. PMID 6131142 DOI: 10.1002/Jnr.490080408  0.28
1995 Walker DG, Yasuhara O, Patston PA, McGeer EG, McGeer PL. Complement C1 inhibitor is produced by brain tissue and is cleaved in Alzheimer disease. Brain Research. 675: 75-82. PMID 7796155 DOI: 10.1016/0006-8993(95)00041-N  0.279
2009 Borenstein AR, Mortimer JA, Schellenberg GD, Galasko D, McGeer PL, Steele JC. The ALS/PDC syndrome of Guam and the cycad hypothesis. Neurology. 72: 473, 476; author rep. PMID 19188582 DOI: 10.1212/01.Wnl.0000344257.59693.Cf  0.279
2011 McGeer PL, Steele JC. The ALS/PDC syndrome of Guam: potential biomarkers for an enigmatic disorder. Progress in Neurobiology. 95: 663-9. PMID 21527311 DOI: 10.1016/J.Pneurobio.2011.04.001  0.278
1992 Peppard RF, Martin WR, Carr GD, Grochowski E, Schulzer M, Guttman M, McGeer PL, Phillips AG, Tsui JK, Calne DB. Cerebral glucose metabolism in Parkinson's disease with and without dementia. Archives of Neurology. 49: 1262-8. PMID 1449406 DOI: 10.1001/Archneur.1992.00530360060019  0.278
1993 Rogers J, Kirby LC, Hempelman SR, Berry DL, McGeer PL, Kaszniak AW, Zalinski J, Cofield M, Mansukhani L, Willson P. Clinical trial of indomethacin in Alzheimer's disease. Neurology. 43: 1609-11. PMID 8351023 DOI: 10.1212/Wnl.43.8.1609  0.277
1988 Mizukawa K, McGeer PL, Vincent SR, McGeer EG. Ultrastructure of reduced nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase-positive neurons in the cat cerebral cortex, amygdala and caudate nucleus. Brain Research. 452: 286-92. PMID 3401736 DOI: 10.1016/0006-8993(88)90032-7  0.276
2011 Lee M, Suk K, Kang Y, McGeer E, McGeer PL. Neurotoxic factors released by stimulated human monocytes and THP-1 cells. Brain Research. 1400: 99-111. PMID 21640980 DOI: 10.1016/J.Brainres.2011.05.021  0.276
1984 McGeer PL, McGeer EG. Possible changes in striatal and limbic cholinergic systems in schizophrenia. Archives of General Psychiatry. 34: 1319-23. PMID 45482 DOI: 10.1001/Archpsyc.1977.01770230061003  0.276
1964 McGeer P, McGeer E. Formation of adrenaline by brain tissue Biochemical and Biophysical Research Communications. 17: 502-507. DOI: 10.1016/0006-291X(64)90054-3  0.275
2004 Bissonnette CJ, Klegeris A, McGeer PL, McGeer EG. Interleukin 1alpha and interleukin 6 protect human neuronal SH-SY5Y cells from oxidative damage. Neuroscience Letters. 361: 40-3. PMID 15135888 DOI: 10.1016/J.Neulet.2004.01.005  0.274
1986 Mizukawa K, McGeer PL, Tago H, Peng JH, McGeer EG, Kimura H. The cholinergic system of the human hindbrain studied by choline acetyltransferase immunohistochemistry and acetylcholinesterase histochemistry. Brain Research. 379: 39-55. PMID 2427162 DOI: 10.1016/0006-8993(86)90253-2  0.273
2005 Klegeris A, Bissonnette CJ, McGeer PL. Modulation of human microglia and THP-1 cell toxicity by cytokines endogenous to the nervous system. Neurobiology of Aging. 26: 673-82. PMID 15708442 DOI: 10.1016/J.Neurobiolaging.2004.06.012  0.272
2001 Klegeris A, McGeer PL. Inflammatory cytokine levels are influenced by interactions between THP-1 monocytic, U-373 MG astrocytic, and SH-SY5Y neuronal cell lines of human origin. Neuroscience Letters. 313: 41-4. PMID 11684335 DOI: 10.1016/S0304-3940(01)02251-0  0.271
2000 Klegeris A, Bissonnette CJ, Dorovini-Zis K, McGeer PL. Expression of complement messenger RNAs by human endothelial cells. Brain Research. 871: 1-6. PMID 10882776 DOI: 10.1016/S0006-8993(00)02253-8  0.271
1997 Tomimoto H, Akiguchi I, Matsuo A, Terai K, Wakita H, Kimura J, McGeer PL, Budka H. Encephalitogenic peptide (EP) in human cerebrovascular white matter lesions. Neuroreport. 8: 3727-30. PMID 9427359 DOI: 10.1097/00001756-199712010-00014  0.271
2011 Ryu JK, Jantaratnotai N, Serrano-Perez MC, McGeer PL, McLarnon JG. Block of purinergic P2X7R inhibits tumor growth in a C6 glioma brain tumor animal model. Journal of Neuropathology and Experimental Neurology. 70: 13-22. PMID 21157381 DOI: 10.1097/Nen.0B013E318201D4D4  0.27
2002 Wakita H, Tomimoto H, Akiguchi I, Matsuo A, Lin JX, Ihara M, McGeer PL. Axonal damage and demyelination in the white matter after chronic cerebral hypoperfusion in the rat. Brain Research. 924: 63-70. PMID 11743996 DOI: 10.1016/S0006-8993(01)03223-1  0.27
1992 Yamada T, Kawamata T, Walker DG, McGeer PL. Vimentin immunoreactivity in normal and pathological human brain tissue. Acta Neuropathologica. 84: 157-62. PMID 1523971 DOI: 10.1007/BF00311389  0.27
1988 Kamo H, Kim SU, McGeer PL, Tago H, Shin DH. Transplantation of cultured human adrenal chromaffin cells into 6-hydroxydopamine-lesioned rat brain. Synapse (New York, N.Y.). 1: 324-8. PMID 2901789 DOI: 10.1002/Syn.890010405  0.27
1988 Calne DB, McGeer PL. Tissue Transplantation for Parkinson's Disease Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 15: 364-365. DOI: 10.1017/S0317167100028055  0.27
1967 McGeer EG, Gibson S, Wada JA, McGeer PL. Distribution of tyrosine hydroxylase activity in adult and developing brain. Canadian Journal of Biochemistry. 45: 1943-52. PMID 6082577 DOI: 10.1139/O67-227  0.269
2012 Hashioka S, Klegeris A, McGeer PL. The histone deacetylase inhibitor suberoylanilide hydroxamic acid attenuates human astrocyte neurotoxicity induced by interferon-γ. Journal of Neuroinflammation. 9: 113. PMID 22647614 DOI: 10.1186/1742-2094-9-113  0.269
2010 Hashioka S, Klegeris A, Schwab C, Yu S, McGeer PL. Differential expression of interferon-gamma receptor on human glial cells in vivo and in vitro. Journal of Neuroimmunology. 225: 91-9. PMID 20554027 DOI: 10.1016/J.Jneuroim.2010.04.023  0.269
2007 Hashioka S, Klegeris A, Monji A, Kato T, Sawada M, McGeer PL, Kanba S. Antidepressants inhibit interferon-gamma-induced microglial production of IL-6 and nitric oxide. Experimental Neurology. 206: 33-42. PMID 17481608 DOI: 10.1016/J.Expneurol.2007.03.022  0.267
1994 Klegeris A, McGeer PL. Inhibition of respiratory burst in macrophages by complement receptor blockade. European Journal of Pharmacology. 260: 273-7. PMID 7988657 DOI: 10.1016/0014-2999(94)90351-4  0.267
1987 Cumming P, Kamo H, McGeer EG, McGeer PL. Toxicity of p-methoxyphenol to dopamine neurons in the rat substantia nigra. Neuropharmacology. 26: 1795-7. PMID 2893988 DOI: 10.1016/0028-3908(87)90136-5  0.267
2011 Lee M, Jantaratnotai N, McGeer E, McLarnon JG, McGeer PL. Mg2+ ions reduce microglial and THP-1 cell neurotoxicity by inhibiting Ca2+ entry through purinergic channels. Brain Research. 1369: 21-35. PMID 21040713 DOI: 10.1016/J.Brainres.2010.10.084  0.266
1977 Hattori T, McGeer PL. Electron microscopic autoradiography on delta8-[3H]tetrahydrocannabinol localization in brain tissue. Toxicology and Applied Pharmacology. 39: 307-11. PMID 66776 DOI: 10.1016/0041-008X(77)90163-6  0.266
1989 Tago H, McGeer PL, McGeer EG, Akiyama H, Hersh LB. Distribution of choline acetyltransferase immunopositive structures in the rat brainstem. Brain Research. 495: 271-97. PMID 2765931 DOI: 10.1016/0006-8993(89)90221-7  0.265
2009 Qing H, Wong W, McGeer E, McGeer P. P3.191 LRRK2 phosphorylates alpha synuclein at serine 129: Parkinson disease implications Parkinsonism & Related Disorders. 15: S197. DOI: 10.1016/S1353-8020(09)70755-2  0.265
1995 Oken RJ, McGeer PL. Pick's disease: possible new directions in prophylaxis and therapy. The Annals of Pharmacotherapy. 29: 538. PMID 7655140 DOI: 10.1177/106002809502900515  0.264
2008 Miklossy J, Martins R, Darbinian N, Khalili K, McGeer PL. Type 2 Diabetes: Local Inflammation and Direct Effect of Bacterial Toxic Components The Open Pathology Journal. 2: 86-95. DOI: 10.2174/1874375700802010086  0.264
2001 McGeer EG, McGeer PL. Innate immunity in Alzheimer's disease: a model for local inflammatory reactions. Molecular Interventions. 1: 22-9. PMID 14993335  0.264
2001 Klegeris A, Schwab C, Bissonnette CJ, McGeer PL. Induction of complement C9 messenger RNAs in human neuronal cells by inflammatory stimuli: relevance to neurodegenerative disorders. Experimental Gerontology. 36: 1179-88. PMID 11404058 DOI: 10.1016/S0531-5565(00)00265-5  0.264
2002 Schwab C, McGeer PL. Complement activated C4d immunoreactive oligodendrocytes delineate small cortical plaques in multiple sclerosis. Experimental Neurology. 174: 81-8. PMID 11869036 DOI: 10.1006/Exnr.2001.7851  0.264
2006 Miklossy J, Vileno B, Forro L, Miller L, Martins RN, McGeer PL. P4-034: Beta amyloid deposition and hyperphosphorylated tau are also present in the degenerating pancreas in type 2 diabetes Alzheimer's & Dementia. 2: S523-S523. DOI: 10.1016/J.Jalz.2006.05.1772  0.263
1989 Singh VK, McGeer PL. Antibody production to choline acetyltransferase purified from human brain. Life Sciences. 15: 901-13. PMID 4220260 DOI: 10.1016/0024-3205(74)90006-X  0.263
1982 Nagai T, Kimura H, Maeda T, McGeer P, Peng F, McGeer E. Cholinergic projections from the basal forebrain of rat to the amygdala The Journal of Neuroscience. 2: 513-520. DOI: 10.1523/Jneurosci.02-04-00513.1982  0.262
2001 McGeer PL, McGeer EG. Inflammation, autotoxicity and Alzheimer disease. Neurobiology of Aging. 22: 799-809. PMID 11754986 DOI: 10.1016/S0197-4580(01)00289-5  0.262
1989 Parks RW, Crockett DJ, McGeer PL. Systems model of cortical organization: Positron emission tomography and neuropsychological test performance Archives of Clinical Neuropsychology. 4: 335-349. DOI: 10.1093/Arclin/4.4.335  0.262
1981 Noda Y, Kimura H, McGeer PL. Glycolysis in rat neostriatal slices following kainic acid injections. Brain Research. 214: 451-4. PMID 6786706 DOI: 10.1016/0006-8993(81)91211-7  0.262
1989 Walker DG, Boyes BE, McGeer PL, McGeer EG. Strategies for the identification of novel brain specific genes affected in Alzheimer disease. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 16: 483-9. PMID 2509057 DOI: 10.1017/S0317167100029814  0.262
2009 Qing H, Wong W, McGeer EG, McGeer PL. Lrrk2 phosphorylates alpha synuclein at serine 129: Parkinson disease implications. Biochemical and Biophysical Research Communications. 387: 149-52. PMID 19576176 DOI: 10.1016/J.Bbrc.2009.06.142  0.261
1997 McGeer PL, Schulzer M, McGeer EG. Steroid therapy in AD Neurology. 48: 1474-1474. DOI: 10.1212/Wnl.48.5.1474  0.261
1988 Okoyama S, Tago H, McGeer PL, Hersh LB, Kimura H. Cholinergic divergent projections from rat basal forebrain to the hippocampus and olfactory bulb. Neuroscience Letters. 83: 77-81. PMID 2831479 DOI: 10.1016/0304-3940(87)90219-9  0.26
1998 Walker DG, McGeer PL. Vitronectin expression in Purkinje cells in the human cerebellum. Neuroscience Letters. 251: 109-12. PMID 9718986 DOI: 10.1016/S0304-3940(98)00517-5  0.26
2006 Arai T, Klegeris A, Hosokawa M, Guo J, McGeer PL. P3-335: Distinct isoforms and phosphorylation states of tau expressed in human cultured cells and organs Alzheimer's & Dementia. 2: S473-S473. DOI: 10.1016/J.Jalz.2006.05.1605  0.259
1966 Sen NP, McGeer PL. 4-Methoxyphenylethylamine and 3,4-dimethoxyphenylethylamine in human urine. Biochemical and Biophysical Research Communications. 14: 227-32. PMID 5836511 DOI: 10.1016/0006-291X(64)90440-1  0.259
1979 Boyko WJ, Galabru CK, McGeer EG, McGeer PL. Thalamic injections of kainic acid produce myocardial necrosis. Life Sciences. 25: 87-98. PMID 481126 DOI: 10.1016/0024-3205(79)90494-6  0.258
2012 Guo J, McGeer P. P1-330: Simple in vitro screening assays for agents that inhibit beta-amyloid deposition or promote beta-amyloid phagocytosis Alzheimer's & Dementia. 8: P221-P221. DOI: 10.1016/J.Jalz.2012.05.2016  0.258
2008 Hashioka S, Klegeris A, Schwab C, McGeer PL. P3-360: Human astrocytes and human U373 MG astrocytoma cells become neurotoxic when stimulated by interferon-γ Alzheimer's & Dementia. 4: T627-T627. DOI: 10.1016/J.Jalz.2008.05.1930  0.257
1981 Kimura H, McGeer PL, Peng JH, McGeer EG. The central cholinergic system studied by choline acetyltransferase immunohistochemistry in the cat. The Journal of Comparative Neurology. 200: 151-201. PMID 7287919 DOI: 10.1002/Cne.902000202  0.257
1992 McGeer PL, Kawamata T, Walker DG. Distribution of clusterin in Alzheimer brain tissue. Brain Research. 579: 337-41. PMID 1378350  0.255
2014 Lee M, Narayanan S, McGeer EG, McGeer PL. Aurin tricarboxylic acid protects against red blood cell hemolysis in patients with paroxysmal nocturnal hemoglobinemia. Plos One. 9: e87316. PMID 24489894 DOI: 10.1371/Journal.Pone.0087316  0.255
2011 Lee M, Schwab C, McGeer PL. Astrocytes are GABAergic cells that modulate microglial activity. Glia. 59: 152-65. PMID 21046567 DOI: 10.1002/Glia.21087  0.254
1998 Yasojima K, Schwab C, McGeer EG, McGeer PL. Human heart generates complement proteins that are upregulated and activated after myocardial infarction. Circulation Research. 83: 860-9. PMID 9776733 DOI: 10.1161/01.Res.83.8.860  0.254
1992 Yamada T, McGeer PL, McGeer EG. Appearance of paired nucleated, Tau-positive glia in patients with progressive supranuclear palsy brain tissue. Neuroscience Letters. 135: 99-102. PMID 1371861 DOI: 10.1016/0304-3940(92)90145-W  0.254
1977 Singh VK, McGeer PL. Studies on choline acetyltransferase isolated from human brain. Neurochemical Research. 2: 281-291. PMID 24272055 DOI: 10.1007/Bf00969358  0.254
2006 Wszolek ZK, Baba Y, Mackenzie IR, Uitti RJ, Strongosky AJ, Broderick DF, Baker MC, Melquist S, Hutton ML, Tsuboi Y, Allanson JE, Carr J, Kumar A, Calne SM, Miklossy J, ... McGeer PL, et al. Autosomal dominant dystonia-plus with cerebral calcifications. Neurology. 67: 620-5. PMID 16924015 DOI: 10.1212/01.Wnl.0000230141.40784.09  0.252
2006 Miklossy J, Rosemberg S, McGeer PL. P3-288: Beta amyloid deposition in the atrophic form of general paresis Alzheimer's & Dementia. 2: S460-S460. DOI: 10.1016/J.Jalz.2006.05.1557  0.252
1999 McGeer EG, McGeer PL. Brain inflammation in Alzheimer disease and the therapeutic implications. Current Pharmaceutical Design. 5: 821-36. PMID 10526088  0.251
1997 Schwab C, Steele JC, McGeer PL. Dystrophic neurites are associated with early stage extracellular neurofibrillary tangles in the parkinsonism-dementia complex of Guam. Acta Neuropathologica. 94: 486-92. PMID 9386782 DOI: 10.1007/s004010050737  0.25
1996 Matsuo A, Lee G, Terai K, McGeer P. 70 Expression of presenilin-like immunoreactivity in late onset Alzheimer disease and control brains Neurobiology of Aging. 17: S18. DOI: 10.1016/S0197-4580(96)80072-8  0.25
1989 Zhu SG, McGeer EG, Singh EA, McGeer PL. Tetrahydroaminoacridine potentiates neurotoxicity of quinolinic acid in rat striatum. Neuroscience Letters. 95: 252-6. PMID 2976129 DOI: 10.1016/0304-3940(88)90666-0  0.25
1991 Tooyama I, Akiyama H, McGeer PL, Hara Y, Yasuhara O, Kimura H. Acidic fibroblast growth factor-like immunoreactivity in brain of Alzheimer patients. Neuroscience Letters. 121: 155-8. PMID 1708473 DOI: 10.1016/0304-3940(91)90673-H  0.248
2018 De Lorenzi E, Chiari M, Colombo R, Cretich M, Sola L, Vanna R, Gagni P, Bisceglia F, Morasso C, Lin JS, Lee M, McGeer PL, Barron AE. Evidence that the Human Innate Immune Peptide LL-37 May Be a Binding Partner of Abeta and Inhibitor of Fibril Assembly Biophysical Journal. 114: 393a. DOI: 10.1016/J.Bpj.2017.11.2174  0.247
2007 Zhang W, Dallas S, Zhang D, Guo JP, Pang H, Wilson B, Miller DS, Chen B, Zhang W, McGeer PL, Hong JS, Zhang J. Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha-synuclein. Glia. 55: 1178-88. PMID 17600340 DOI: 10.1002/Glia.20532  0.247
1997 McGeer PL, McGeer EG. 3-12-06 Glial cell reactions in dementia: Pathophysiology and therapeutic interventions Journal of the Neurological Sciences. 150: S154-S155. DOI: 10.1016/S0022-510X(97)85604-3  0.247
1999 Steele JC, Morris HR, Lees AJ, Perez-Tur J, McGeer PL. Atypical parkinsonism in the French West Indies. Lancet. 354: 1474. PMID 10543696 DOI: 10.1016/S0140-6736(05)77614-5  0.246
2012 Jantaratnotai N, McGeer PL, McLarnon JG. Mechanisms of Mg2+ inhibition of BzATP-dependent Ca2+ responses in THP-1 monocytes. Brain Research. 1442: 1-8. PMID 22297175 DOI: 10.1016/J.Brainres.2012.01.004  0.246
1989 Zhu SG, McGeer EG, McGeer PL. Effect of MK-801, kynurenate, glycine, dextrorphan and 4-acetylpyridine on striatal toxicity of quinolinate. Brain Research. 481: 356-60. PMID 2524238 DOI: 10.1016/0006-8993(89)90814-7  0.245
1992 McGeer EG, Singh EA, McGeer PL. Apparent anterograde transport of basic fibroblast growth factor in the rat nigrostriatal dopamine system. Neuroscience Letters. 148: 31-3. PMID 1284444 DOI: 10.1016/0304-3940(92)90797-B  0.245
1989 McGeer EG, McGeer PL, Akiyama H, Harrop R. Cortical glutaminase, beta-glucuronidase and glucose utilization in Alzheimer's disease. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 16: 511-5. PMID 2804813 DOI: 10.1017/S0317167100029851  0.245
1994 McGeer P, Yasuhara O, Klegeris A, Walker D, McGeer E. Immune mechanism in senile plaque formation Pathophysiology. 1: 55. DOI: 10.1016/0928-4680(94)90135-X  0.244
1985 Araki M, McGeer PL, McGeer EG. Presumptive gamma-aminobutyric acid pathways from the midbrain to the superior colliculus studied by a combined horseradish peroxidase-gamma-aminobutyric acid transaminase pharmacohistochemical method. Neuroscience. 13: 433-9. PMID 6096762 DOI: 10.1016/0306-4522(84)90241-0  0.243
1999 Tanhehco EJ, Yasojima K, McGeer PL, Washington RA, Kilgore KS, Homeister JW, Lucchesi BR. Preconditioning reduces tissue complement gene expression in the rabbit isolated heart. The American Journal of Physiology. 277: H2373-80. PMID 10600858 DOI: 10.1152/Ajpheart.1999.277.6.H2373  0.243
2010 Zou WQ, Langeveld J, Xiao X, Chen S, McGeer PL, Yuan J, Payne MC, Kang HE, McGeehan J, Sy MS, Greenspan NS, Kaplan D, Wang GX, Parchi P, Hoover E, et al. PrP conformational transitions alter species preference of a PrP-specific antibody. The Journal of Biological Chemistry. 285: 13874-84. PMID 20194495 DOI: 10.1074/Jbc.M109.088831  0.243
1991 Parks RW, Long DL, Levine DS, Crockett DJ, McGeer EG, McGeer PL, Dalton IE, Zec RF, Becker RE, Coburn KL. Parallel distributed processing and neural networks: origins, methodology and cognitive functions. The International Journal of Neuroscience. 60: 195-214. PMID 1787049 DOI: 10.3109/00207459109080640  0.243
1985 McGeer PL. The 12th J. A. F. Stevenson memorial lecture. Aging, Alzheimer's disease, and the cholinergic system. Canadian Journal of Physiology and Pharmacology. 62: 741-54. PMID 6149804 DOI: 10.1139/Y84-123  0.242
2000 Schwab C, McGeer PL. Abeta42-carboxy-terminal-like immunoreactivity is associated with intracellular neurofibrillary tangles and pick bodies. Experimental Neurology. 161: 527-34. PMID 10686074 DOI: 10.1006/exnr.1999.7307  0.242
2001 Yasojima K, McGeer EG, McGeer PL. Relationship between beta amyloid peptide generating molecules and neprilysin in Alzheimer disease and normal brain. Brain Research. 919: 115-21. PMID 11689168 DOI: 10.1016/S0006-8993(01)03008-6  0.24
2008 Miklossy J, Kasas S, Zurn AD, McCall S, Yu S, McGeer PL. Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis. Journal of Neuroinflammation. 5: 40. PMID 18817547 DOI: 10.1186/1742-2094-5-40  0.24
1977 Jakubovic A, McGeer PL. Biochemical changes in rat testicular cells in vitro produced by cannabinoids and alcohol: metabolism and incorporation of labeled glucose, amino acids, and nucleic acid precursors. Toxicology and Applied Pharmacology. 41: 473-86. PMID 918982 DOI: 10.1016/S0041-008X(77)80003-3  0.239
1994 McGeer PL, Walker DG, Akiyama H, Yasuhara O, McGeer EG. Involvement of microglia in Alzheimer's disease. Neuropathology and Applied Neurobiology. 20: 191-2. PMID 8072657  0.238
2000 Tanhehco EJ, Yasojima K, McGeer PL, Washington RA, Lucchesi BR. Free radicals upregulate complement expression in rabbit isolated heart. American Journal of Physiology. Heart and Circulatory Physiology. 279: H195-201. PMID 10899056 DOI: 10.1152/Ajpheart.2000.279.1.H195  0.237
1961 MCGEER PL, BOULDING JE, GIBSON WC, FOULKES RG. Drug-induced extrapyramidal reactions. Treatment with diphenhydramine hydrochloride and dihydroxyphenylalanine. Jama. 177: 665-70. PMID 13773933 DOI: 10.1001/Jama.1961.03040360001001  0.236
1988 Tomimoto H, Kamo H, Kameyama M, McGeer PL, Kimura H. Descending projections of the basal forebrain in the rat demonstrated by the anterograde neural tracer Phaseolus vulgaris leucoagglutinin (PHA-L). Brain Research. 425: 248-55. PMID 2827844 DOI: 10.1016/0006-8993(87)90507-5  0.236
1961 McGeer PL, McGeer EG, Griffin MC. EXCRETION OF 4-AMINO-5-IMIDAZOLECARBOXAMIDE IN HUMAN URINE Canadian Journal of Biochemistry and Physiology. 39: 591-603. DOI: 10.1139/O61-059  0.236
2011 Lee M, McGeer EG, McGeer PL. Mechanisms of GABA release from human astrocytes. Glia. 59: 1600-11. PMID 21748804 DOI: 10.1002/Glia.21202  0.236
2000 Tanhehco EJ, Yasojima K, McGeer PL, McGeer EG, Lucchesi BR. Preconditioning reduces myocardial complement gene expression in vivo. American Journal of Physiology. Heart and Circulatory Physiology. 279: H1157-65. PMID 10993779 DOI: 10.1152/Ajpheart.2000.279.3.H1157  0.236
1992 McGeer PL, Harada N, Kimura H, McGeer EG, Schulzer M. Prevalence of Dementia amongst Elderly Japanese with Leprosy: Apparent Effect of Chronic Drug Therapy Dementia and Geriatric Cognitive Disorders. 3: 146-149. DOI: 10.1159/000107010  0.235
2014 Hashioka S, Wang YF, Little JP, Choi HB, Klegeris A, McGeer PL, McLarnon JG. Purinergic responses of calcium-dependent signaling pathways in cultured adult human astrocytes. Bmc Neuroscience. 15: 18. PMID 24447580 DOI: 10.1186/1471-2202-15-18  0.235
1999 Yasojima K, McGeer EG, McGeer PL. Tangled areas of Alzheimer brain have upregulated levels of exon 10 containing tau mRNA. Brain Research. 831: 301-5. PMID 10412011 DOI: 10.1016/S0006-8993(99)01486-9  0.235
1992 McGeer PL, Akiyama H, Kawamata T, Yamada T, Walker DG, Ishii T. Immunohistochemical localization of beta-amyloid precursor protein sequences in Alzheimer and normal brain tissue by light and electron microscopy. Journal of Neuroscience Research. 31: 428-42. PMID 1640495 DOI: 10.1002/jnr.490310305  0.235
1992 Wong PT, McGeer PL, McGeer EG. Decreased prostaglandin synthesis in postmortem cerebral cortex from patients with Alzheimer's disease. Neurochemistry International. 21: 197-202. PMID 1303152  0.234
1975 Singh VK, McGeer EG, McGeer PL. Two immunologically different choline acetyltransferases in human neostriatum. Brain Research. 96: 187-91. PMID 1175001 DOI: 10.1016/0006-8993(75)90595-8  0.232
1988 Araki M, McGeer PL, Kimura H. The efferent projections of the rat lateral habenular nucleus revealed by the PHA-L anterograde tracing method. Brain Research. 441: 319-30. PMID 2451982 DOI: 10.1016/0006-8993(88)91410-2  0.232
1992 Shigematsu K, McGeer PL, Walker DG, Ishii T, McGeer EG. Reactive microglia/macrophages phagocytose amyloid precursor protein produced by neurons following neural damage. Journal of Neuroscience Research. 31: 443-53. PMID 1640496 DOI: 10.1002/Jnr.490310306  0.232
1963 McGEER PL. Excretion of 4-Amino-5-Imidazolecarboxamide by Mental Patients Archives of General Psychiatry. 8: 418. DOI: 10.1001/Archpsyc.1963.01720100108011  0.231
1962 McGeer EG, McGeer PL, Miller JR, Derry D, Nichol C. EXCRETION OF 4-AMINO-5-IMIDAZOLECARBOXAMIDE AND CREATINE:CREATININE RATIOS IN HUMAN AND MOUSE MUSCULAR DYSTROPHY Canadian Journal of Biochemistry and Physiology. 40: 13-23. DOI: 10.1139/O62-003  0.229
2004 Zhang XJ, McGeer PL. Correlation of complement receptor type 2 with senile plaque and neurofibrillar tangles in the hippocampal and temporal isocortex brain tissue in patients with Alzheimer disease Chinese Journal of Clinical Rehabilitation. 8: 6212-6214.  0.227
1988 McGeer PL, Itagaki S, Boyes BE, McGeer EG. Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology. 38: 1285-91. PMID 3399080 DOI: 10.1212/Wnl.38.8.1285  0.227
2001 Yasojima K, McGeer EG, McGeer PL. 3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA in Alzheimer and control brain. Neuroreport. 12: 2935-8. PMID 11588606  0.227
1962 McGeer EG, McGeer PL. CATECHOLAMINE CONTENT OF SPINAL CORD Canadian Journal of Biochemistry and Physiology. 40: 1141-1151. DOI: 10.1139/O62-128  0.226
1991 Yamada T, McGeer P, McGeer E. Relationship of Complement-Activated Oligodendrocytes to Reactive Microglia and Neuronal Pathology in Neurodegenerative Disease Dementia and Geriatric Cognitive Disorders. 2: 71-77. DOI: 10.1159/000107179  0.225
2012 Lee M, Kwon B, Suk K, McGeer E, McGeer PL. Erratum to: Effects of Obovatol on GSH Depleted Glia-Mediated Neurotoxicity and Oxidative Damage Journal of Neuroimmune Pharmacology. 7: 300-300. DOI: 10.1007/S11481-011-9305-4  0.225
2010 Zou WQ, Langeveld J, Xiao X, Chen S, McGeer PL, Yuan J, Payne MC, Kang HE, McGeehan J, Sy MS, Greenspan NS, Kaplan D, Wang GX, Parchi P, Hoover E, et al. Reply to Kascsak: Definition of the PrP 3F4 epitope revisited Journal of Biological Chemistry. 285: le6. DOI: 10.1074/Jbc.N109.088831  0.225
2004 Guo JP, Petric M, Campbell W, McGeer PL. SARS corona virus peptides recognized by antibodies in the sera of convalescent cases. Virology. 324: 251-6. PMID 15207612 DOI: 10.1016/J.Virol.2004.04.017  0.225
1996 Tooyama I, Uemura S, Kubota Y, Seino Y, Beach TG, Woodhurst WB, McGeer PL, Kimura H. Expression of Major Histocompatibility Complex Class I and II Antigens in the Human Hippocampus with Temporal Lobe Epilepsy. Epilepsia. 37: 64-64. DOI: 10.1111/J.1528-1157.1996.Tb01827.X  0.225
1959 McGeer EG, McGeer PL. Physiological Effects of Schizophrenic Body Fluids Journal of Mental Science. 105: 1-18. DOI: 10.1192/Bjp.105.438.1  0.224
2000 Nakagawa E, Aimi Y, Yasuhara O, Tooyama I, Shimada M, McGeer PL, Kimura H. Enhancement of progenitor cell division in the dentate gyrus triggered by initial limbic seizures in rat models of epilepsy. Epilepsia. 41: 10-8. PMID 10643917 DOI: 10.1111/J.1528-1157.2000.Tb01498.X  0.223
1994 Kawamata T, Higuchi K, Akiguchi I, Hosokawa M, Kogishi K, Tooyama I, Kimura H, McGeer P, McGeer E, Kimura J. Distribution and metabolism of apolipoproteins in the brains with aging and alzheimer-type dementia alzheimer's disease Pathophysiology. 1: 54. DOI: 10.1016/0928-4680(94)90132-5  0.223
1997 McGeer EG, McGeer PL. The role of the immune system in neurodegenerative disorders. Movement Disorders : Official Journal of the Movement Disorder Society. 12: 855-8. PMID 9399206 DOI: 10.1002/Mds.870120604  0.223
1962 SEN NP, McGEER PL, PAUL RM. Imidazolepropionic acid as a urinary metabolite of L-histidine. Biochemical and Biophysical Research Communications. 9: 257-61. PMID 13987921 DOI: 10.1016/0006-291X(62)90069-4  0.222
1989 McGeer PL, Akiyama H, Itagaki S, McGeer EG. Immune system response in Alzheimer's disease. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 16: 516-27. PMID 2804814 DOI: 10.1017/S0317167100029863  0.222
1966 McGeer EG, McGeer PL. Circadian rhythm in pineal tyrosine hydroxylase. Science (New York, N.Y.). 153: 73-4. PMID 5938420 DOI: 10.1126/Science.153.3731.73  0.22
2008 Winkler DF, McGeer PL. Protein labeling and biotinylation of peptides during spot synthesis using biotin p-nitrophenyl ester (biotin-ONp). Proteomics. 8: 961-7. PMID 18324722 DOI: 10.1002/Pmic.200700909  0.22
1982 McGeer PL, McGeer EG. Kainic acid: The neurotoxic breakthrough. Critical Reviews in Toxicology. 10: 1-26. PMID 6280927 DOI: 10.3109/10408448209033629  0.219
1996 BAGCHI SP, MCGEER PL. SOME PROPERTIES OF TYROSINE HYDROXYLASE FROM THE CAUDATE NUCLEUS. Life Sciences (1962). 3: 1195-200. PMID 14225380 DOI: 10.1016/0024-3205(64)90140-7  0.219
1992 McGeer PL, McGeer EG. Complement proteins and complement inhibitors in Alzheimer's disease. Research in Immunology. 143: 621-4. PMID 1455053  0.218
1997 McGeer EG, McGeer PL. Aging, Neurodegenerative Disease and the Brain Canadian Journal On Aging / La Revue Canadienne Du Vieillissement. 16: 218-236. DOI: 10.1017/S071498080001432X  0.218
2000 Lee CY, Ho J, Chow SN, Yasojima K, Schwab C, McGeer PL. Immunoidentification of gonadotropin releasing hormone receptor in human sperm, pituitary and cancer cells. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 44: 170-7. PMID 11028904 DOI: 10.1111/J.8755-8920.2000.440307.X  0.217
1989 Walker DG, O'Kusky JR, McGeer PL. In situ hybridization analysis for herpes simplex virus nucleic acids in Alzheimer disease. Alzheimer Disease and Associated Disorders. 3: 123-31. PMID 2551348 DOI: 10.1097/00002093-198903030-00001  0.215
1974 Jakubovic A, Tait RM, McGeer PL. Excretion of THC and its metabolites in ewes' milk. Toxicology and Applied Pharmacology. 28: 38-43. PMID 4859325 DOI: 10.1016/0041-008X(74)90128-8  0.215
2010 Lee M, Del Soldato P, Sparatore A, McGeer P. Reply to Savolainen: High toxicity of hydrogen sulfide by the inhibition of mitochondrial respiration Journal of Biological Chemistry. 285: le10. DOI: 10.1074/Jbc.N110.115261  0.215
2005 McGeer PL, Sibley J. Sparing of age-related macular degeneration in rheumatoid arthritis. Neurobiology of Aging. 26: 1199-203. PMID 15917104 DOI: 10.1016/J.Neurobiolaging.2005.02.003  0.215
1986 McGeer PL. Brain imaging in Alzheimer's disease. British Medical Bulletin. 42: 24-8. PMID 3513888 DOI: 10.1093/OXFORDJOURNALS.BMB.A072093  0.213
1998 McGeer PL, Schwab C, McGeer E, Haddock RL, Steele JC. Familial nature and continuing morbidity of the ALS-PDC of Guam Neurology. 51: 644.1-644. DOI: 10.1212/Wnl.51.2.644  0.213
2008 Kamo H, Kiriyama Y, Mizoe A, Murase E, Okajima S, Akiguchi I, Hirasawa Y, McGeer PL. A computer support system for neurological anatomical diagnosis. Clinical Neurology and Neurosurgery. 110: 973-8. PMID 18621473 DOI: 10.1016/J.Clineuro.2008.05.022  0.213
1991 McGeer EG, McGeer PL, Harrop R, Akiyama H, Kamo H. Correlations of regional postmortem enzyme activities with premortem local glucose metabolic rates in Alzheimer's disease. Journal of Neuroscience Research. 27: 612-9. PMID 2079721 DOI: 10.1002/Jnr.490270422  0.212
1997 McGeer PL, Schwab C, McGeer EG, Haddock RL, Steele JC. Familial nature and continuing morbidity of the amyotrophic lateral sclerosis-parkinsonism dementia complex of Guam. Neurology. 49: 400-9. PMID 9270568 DOI: 10.1212/Wnl.49.2.400  0.21
2006 McGeer PL, Sibley J. Authors’ response to commentarySparing of age-related macular degeneration in rheumatoid arthritis Neurobiology of Aging. 27. DOI: 10.1016/J.Neurobiolaging.2005.10.001  0.209
2003 MCGEER PL, MCGEER EG, BOULDING JE. Relation of aromatic amino acids to excretory pattern of schizophrenics. Science (New York, N.Y.). 123: 1078-80. PMID 13324153 DOI: 10.1126/Science.123.3207.1078-A  0.207
2017 Cao Y, Wang X, Shi X, Clee SM, McGeer PL, Wolf MO, Orvig C. Biological Imaging with Medium-Sensitive Bichromatic Flexible Fluorescent (FlexFluor) Dyes. Angewandte Chemie (International Ed. in English). PMID 29045760 DOI: 10.1002/Anie.201708529  0.207
2015 Hashioka S, McGeer PL, Miyaoka T, Wake R, Horiguchi J. Can inhibition of microglial activation cure schizophrenia? Schizophrenia Research. PMID 26254144 DOI: 10.1016/J.Schres.2015.07.042  0.207
2001 Burnakis TG, Fleming M, Konstam MA, Demopoulos LA, Grant KD, Haldey EJ, Pappagallo M, Minic M, McGeer PL, McGeer EG, Yasojima K, Singh G, White WB, Whelton A, Mukherjee D, et al. Cardiovascular events and COX-2 inhibitors [1] (multiple letters) Journal of the American Medical Association. 286: 2808-2813. PMID 11735741 DOI: 10.1001/Jama.286.22.2808  0.205
1988 Boyes BE, Walker DG, McGeer PL. Separation of large DNA restriction fragments on a size-exclusion column by a nonideal mechanism. Analytical Biochemistry. 170: 127-34. PMID 2839050 DOI: 10.1016/0003-2697(88)90099-1  0.205
2000 McGeer PL, McGeer EG. Autotoxicity and Alzheimer disease. Archives of Neurology. 57: 789-90. PMID 10867774 DOI: 10.1001/Archneur.57.6.789  0.204
1993 Yamada T, Calne DB, Akiyama H, McGeer EG, McGeer PL. Further observations on Tau-positive glia in the brains with progressive supranuclear palsy. Acta Neuropathologica. 85: 308-15. PMID 7681616 DOI: 10.1007/Bf00227727  0.204
1998 Yasojima K, Kilgore KS, Washington RA, Lucchesi BR, McGeer PL. Complement gene expression by rabbit heart: upregulation by ischemia and reperfusion. Circulation Research. 82: 1224-30. PMID 9633921 DOI: 10.1161/01.Res.82.11.1224  0.204
2006 Patrick DM, Petric M, Skowronski DM, Guasparini R, Booth TF, Krajden M, McGeer P, Bastien N, Gustafson L, Dubord J, Macdonald D, David ST, Srour LF, Parker R, Andonov A, et al. An Outbreak of Human Coronavirus OC43 Infection and Serological Cross-reactivity with SARS Coronavirus. The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie MéDicale / Ammi Canada. 17: 330-6. PMID 18382647 DOI: 10.1155/2006/152612  0.204
2005 Stoessl AJ, McGeer PL. Hot spots: can positron emission tomography offer insights into the pathogenesis of PD? Annals of Neurology. 57: 161-2. PMID 15668974 DOI: 10.1002/Ana.20382  0.204
2000 McGeer PL. Innate immunity, autotoxicity and degenerative neurologies Neurobiology of Aging. 21: 285. DOI: 10.1016/S0197-4580(00)83233-9  0.203
1997 Terai K, Walker DG, McGeer EG, McGeer PL. Neurons express proteins of the classical complement pathway in Alzheimer disease. Brain Research. 769: 385-90. PMID 9374211 DOI: 10.1016/S0006-8993(97)00849-4  0.202
1962 Nichol C, McGeer PL, Miller JR. CREATINE KINASE IN NORMAL AND DYSTROPHIC MOUSE MUSCLE Canadian Journal of Biochemistry and Physiology. 40: 443-447. DOI: 10.1139/O62-051  0.201
1991 Peppard RF, Martin WR, Clark CM, Carr GD, McGeer PL, Calne DB. Cortical glucose metabolism in Parkinson's and Alzheimer's disease. Journal of Neuroscience Research. 27: 561-8. PMID 2079717 DOI: 10.1002/JNR.490270417  0.201
1996 Yasuhara O, Nakamura S, Akiguchi I, Kimura J, McGeer P. 719 Expression of interleukin-1 receptor antagonist protein in Alzheimer's Disease, pick's disease and control cases Neurobiology of Aging. 17: S178-S179. DOI: 10.1016/S0197-4580(96)80721-4  0.2
1982 Brownell GL, Budinger TF, Lauterbur PC, McGeer PL. Positron tomography and nuclear magnetic resonance imaging. Science (New York, N.Y.). 215: 619-26. PMID 17842371 DOI: 10.1126/Science.215.4533.619  0.2
2006 Miklossy J, Doudet DD, Schwab C, Yu S, McGeer EG, McGeer PL. Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys. Experimental Neurology. 197: 275-83. PMID 16336966 DOI: 10.1016/J.Expneurol.2005.10.034  0.199
1993 Akiyama H, Yamada T, McGeer PL, Kawamata T, Tooyama I, Ishii T. Columnar arrangement of beta-amyloid protein deposits in the cerebral cortex of patients with Alzheimer's disease. Acta Neuropathologica. 85: 400-3. PMID 8480513  0.199
2001 Morris HR, Al-Sarraj S, Schwab C, Gwinn-Hardy K, Perez-Tur J, Wood NW, Hardy J, Lees AJ, McGeer PL, Daniel SE, Steele JC. A clinical and pathological study of motor neurone disease on Guam. Brain : a Journal of Neurology. 124: 2215-22. PMID 11673323 DOI: 10.1093/Brain/124.11.2215  0.199
1987 McGeer EG, McGeer PL, Kamo H, Tago H, Harrop R. Cortical metabolism, acetylcholinesterase staining and pathological changes in Alzheimer's disease. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 13: 511-6. PMID 2431752 DOI: 10.1017/S0317167100037227  0.199
1979 Eccles JC, McGeer PL. Ionotropic and metabotropic neurotransmission Trends in Neurosciences. 2: 39-40. DOI: 10.1016/0166-2236(79)90017-1  0.199
1962 Miller J, Mcgeer P, Nichol C. SERUM-CREATINE-KINASE AND CARRIER DETECTION IN MUSCULAR DYSTROPHY The Lancet. 280: 201. DOI: 10.1016/S0140-6736(62)90091-0  0.198
1959 Smith DM, Paul RM, McGeer EG, McGeer PL. A GENERAL CHROMATOGRAPHIC SURVEY OF AROMATIC COMPOUNDS OBTAINED FROM URINE Canadian Journal of Biochemistry and Physiology. 37: 1493-1515. DOI: 10.1139/O59-168  0.196
1991 McGeer PL, McGeer EG, Kawamata T, Yamada T, Akiyama H. Reactions of the immune system in chronic degenerative neurological diseases. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 18: 376-9. PMID 1933684 DOI: 10.1017/S0317167100032479  0.195
1974 McGeer PL, McGeer EG. Neurotransmitter synthetic enzymes. Progress in Neurobiology. 2: 69-117. PMID 4149290 DOI: 10.1016/0301-0082(73)90007-5  0.193
2000 Foley P, Mizuno Y, Nagatsu T, Sano A, Youdin M, McGeer P, McGeer E, Riederer P. The L-DOPA story - an early Japanese contribution Parkinsonism & Related Disorders. 6: 1. DOI: 10.1016/S1353-8020(99)90001-9  0.191
1991 Akiyama H, Kawamata T, Dedhar S, McGeer PL. Immunohistochemical localization of vitronectin, its receptor and beta-3 integrin in Alzheimer brain tissue. Journal of Neuroimmunology. 32: 19-28. PMID 1705945 DOI: 10.1016/0165-5728(91)90067-H  0.189
1989 Itagaki S, McGeer PL, Akiyama H, Beattie BL, Walker DG, Moore GR, McGeer EG. A case of adult-onset dementia with argyrophilic grains. Annals of Neurology. 26: 685-9. PMID 2817845 DOI: 10.1002/Ana.410260517  0.189
1963 Sen N, McGeer P. Gas chromatography of phenolic and catecholic amines as the trimethylsilyl ethers Biochemical and Biophysical Research Communications. 13: 390-393. DOI: 10.1016/0006-291X(63)90353-X  0.186
1971 McGeer EG, McGeer PL, Wada JA. Distribution of tyrosine hydroxylase in human and animal brain. Journal of Neurochemistry. 18: 1647-58. PMID 4998978 DOI: 10.1111/J.1471-4159.1971.Tb03738.X  0.185
1979 Brown WT, Sanberg PR, McGeer PL. Corticosteroids and chorea. Archives of Neurology. 36: 452-3. PMID 156536 DOI: 10.1001/Archneur.1979.00500430082020  0.185
1997 Schwab C, Steele JC, McGeer EG, McGeer PL. Amyloid P immunoreactivity precedes C4d deposition on extracellular neurofibrillary tangles. Acta Neuropathologica. 93: 87-92. PMID 9006661 DOI: 10.1007/S004010050586  0.185
1996 Lee MC, Yang KH, Park CS, Tai T, McGeer PL, Kim SU. DISTRIBUTION OF A-PATHWAY GANGLIOSIDES IN NORMAL AND ALZHEIMER BRAINS Journal of Neuropathology and Experimental Neurology. 55: 646. DOI: 10.1097/00005072-199605000-00172  0.184
1998 Schwab C, Steele JC, McGeer PL. Pyramidal neuron loss is matched by ghost tangle increase in Guam parkinsonism-dementia hippocampus. Acta Neuropathologica. 96: 409-16. PMID 9797006 DOI: 10.1007/s004010050912  0.182
1956 MCGEER PL, MCGEER EG, GIBSON WC. Aromatic excretory pattern of schizophrenics. Science (New York, N.Y.). 123: 1029-30. PMID 13324138 DOI: 10.1126/Science.123.3206.1029  0.182
2001 McGeer PL, Yasojima K, McGeer EG. Inflammation in Parkinson's disease. Advances in Neurology. 86: 83-9. PMID 11554012  0.182
1984 McGeer PL, McGeer EG, Suzuki J, Dolman CE, Nagai T. Aging, Alzheimer's disease, and the cholinergic system of the basal forebrain. Neurology. 34: 741-5. PMID 6539435 DOI: 10.1212/Wnl.34.6.741  0.179
2000 Giacobini E, McGeer PL. Approaches to the treatment of Alzheimer's disease Neuroscience News. 3: 62-70.  0.178
2000 McGEER EG, BROWN WT, McGEER PL. Aromatic metabolism in schizophrenia. II. Bidimensional urinary chromatograms. The Journal of Nervous and Mental Disease. 125: 176-80. PMID 13481714 DOI: 10.1097/00005053-195704000-00003  0.176
1992 Shigematsu K, McGeer PL. Accumulation of amyloid precursor protein in neurons after intraventricular injection of colchicine. The American Journal of Pathology. 140: 787-94. PMID 1373270  0.176
2008 Guo J, Schwab C, Li D, Liu J, Po C, McGeer P. P2-167: Alzheimer disease tangles and threads display multiple tau phosphorylation sites Alzheimer's & Dementia. 4: T419-T419. DOI: 10.1016/j.jalz.2008.05.1241  0.175
1981 Kimura H, McGeer EG, McGeer PL. Metabolic alterations in an animal model of Huntington's disease using the 14C-deoxyglucose method. Journal of Neural Transmission. Supplementum. 103-9. PMID 6448915 DOI: 10.1007/978-3-7091-8582-7_11  0.175
1994 Klegeris A, Walker DG, McGeer PL. Activation of macrophages by Alzheimer beta amyloid peptide. Biochemical and Biophysical Research Communications. 199: 984-91. PMID 7510964 DOI: 10.1006/bbrc.1994.1326  0.172
1966 Newman MA, McGeer PL. A KILLER WHALEOrcinus orcaAT VANCOUVER AQUARIUM International Zoo Yearbook. 6: 257-259. DOI: 10.1111/J.1748-1090.1966.Tb01785.X  0.172
2014 McGeer PL. Dementia challenge: Effective strategies for translating basic research into clinical success in Alzheimer's disease Bmj (Online). 348. DOI: 10.1136/bmj.g1853  0.168
1999 McGeer PL, McGeer EG. Parkinson's disease and the dawn of contemporary neuroscience Neuroscience News. 2: 15-18.  0.167
2002 McGeer PL, McGeer EG. Inflammatory processes in amyotrophic lateral sclerosis. Muscle & Nerve. 26: 459-70. PMID 12362410 DOI: 10.1002/mus.10191  0.167
1987 Kamo H, McGeer PL, Harrop R, McGeer EG, Calne DB, Martin WR, Pate BD. Positron emission tomography and histopathology in Pick's disease. Neurology. 37: 439-45. PMID 3493451 DOI: 10.1212/Wnl.37.3.439  0.165
2007 McGeer EG, McGeer PL. Neuroinflammation, Alzheimer disease, and other aging disorders Pharmacological Mechanisms in Alzheimer's Therapeutics. 149-166. DOI: 10.1007/978-0-387-71522-3_10  0.164
1972 Fibiger HC, Pudritz RE, McGeer PL, McGeer EG. Axonal transport in nigro-striatal and nigro-thalamic neurons: effects of medial forebrain bundle lesions and 6-hydroxydopamine. Journal of Neurochemistry. 19: 1697-708. PMID 4114445 DOI: 10.1111/J.1471-4159.1972.Tb06214.X  0.162
1990 McGeer EG, Peppard RP, McGeer PL, Tuokko H, Crockett D, Parks R, Akiyama H, Calne DB, Beattie BL, Harrop R. 18Fluorodeoxyglucose Positron Emission Tomography Studies in Presumed Alzheimer Cases, Including 13 Serial Scans Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques. 17: 1-11. PMID 2311010 DOI: 10.1017/S0317167100029930  0.162
1989 Akiyama H, Harrop R, McGeer PL, Peppard R, McGeer EG. Crossed cerebellar and uncrossed basal ganglia and thalamic diaschisis in Alzheimer's disease. Neurology. 39: 541-8. PMID 2784550 DOI: 10.1212/Wnl.39.4.541  0.161
1994 Yasuhara O, Aimi Y, Yamada T, Matsuo A, McGeer EG, McGeer PL. Clusterin as a marker for ischaemic Purkinje cells in human brain. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 3: 325-9. PMID 7842303  0.16
1981 Wong PT, McGeer EG, McGeer PL. A sensitive radiometric assay for ornithine aminotransferase: regional and subcellular distributions in rat brain. Journal of Neurochemistry. 36: 501-5. PMID 7007578 DOI: 10.1111/J.1471-4159.1981.Tb01620.X  0.158
1972 McGeer EG, Fibiger HC, McGeer PL. Brain enzymes in amantadine-treated rats. Biochemical Medicine. 6: 189-91. PMID 4402129 DOI: 10.1016/0006-2944(72)90037-3  0.158
1983 McGeer PL, McGeer EG, Nagai T. GABAergic and cholinergic indices in various regions of rat brain after intracerebral injections of folic acid. Brain Research. 260: 107-16. PMID 6824947 DOI: 10.1016/0006-8993(83)90768-0  0.157
1993 Tooyama I, Kawamata T, Walker D, Yamada T, Hanai K, Kimura H, Iwane M, Igarashi K, McGeer EG, McGeer PL. Loss of basic fibroblast growth factor in substantia nigra neurons in Parkinson's disease. Neurology. 43: 372-6. PMID 8437705 DOI: 10.1212/Wnl.43.2.372  0.157
1973 McGeer EG, Fibiger HC, McGeer PL, Brooke S. Temporal changes in amine synthesizing enzymes of rat extrapyramidal structures after hemitransections or 6-hydroxydopamine administration. Brain Research. 52: 289-300. PMID 4144770 DOI: 10.1016/0006-8993(73)90665-3  0.155
2012 Zhang Y, Xu Y, Deng Y, Wong W, McGeer P, Qing H. 2.206 EPIGALLOCAETECHIN GALLATE (EGCG) INHIBITS A-SYNUCLEIN AGGREGATION: A POTENTIAL AGENT FOR PARKINSON DISEASE Parkinsonism & Related Disorders. 18: S116. DOI: 10.1016/S1353-8020(11)70530-2  0.155
1995 Oken RJ, McGeer PL. Creutzfeldt-Jakob disease. Journal of Dental Research. 74: 1836. PMID 8600178 DOI: 10.1177/00220345950740120501  0.155
1973 MCGEER P. GLUTAMIC-ACID DECARBOXYLASE AND CHOLINE ACETYLASE IN HUNTINGTON'S CHOREA AND PARKINSON'S DISEASE The Lancet. 302: 623-624. DOI: 10.1016/S0140-6736(73)92461-6  0.153
1985 McGeer EG, Norman M, Boyes B, O'Kusky J, Suzuki J, McGeer PL. Acetylcholine and aromatic amine systems in postmortem brain of an infant with Down's syndrome Experimental Neurology. 87: 557-570. PMID 2857653 DOI: 10.1016/0014-4886(85)90184-0  0.151
1984 McGeer EG, McGeer PL. Substantia nigra cell death from kainic acid or folic acid injections into the pontine tegmentum. Brain Research. 298: 339-42. PMID 6144364 DOI: 10.1016/0006-8993(84)91433-1  0.149
1985 Araki M, McGeer PL, McGeer EG. Differential effect of kainic acid on somatostatin, GABAergic and cholinergic neurons in the rat striatum. Neuroscience Letters. 53: 197-202. PMID 2858835 DOI: 10.1016/0304-3940(85)90185-5  0.148
1980 Jakubovic A, McGeer EG, McGeer PL. Biochemical alterations induced by cannabinoids in the Leydig cells of the rat testis in vitro: effects on testosterone and protein synthesis. Advances in the Biosciences. 251-64. PMID 756829 DOI: 10.1016/B978-0-08-023759-6.50024-X  0.147
1990 Weinstein DL, Walker DG, Akiyama H, McGeer PL. Herpes simplex virus type I infection of the CNS induces major histocompatibility complex antigen expression on rat microglia. Journal of Neuroscience Research. 26: 55-65. PMID 2359146 DOI: 10.1002/JNR.490260107  0.146
1985 McGeer PL. Dementia of the Alzheimer type Neurology. 35: 447-447. DOI: 10.1212/WNL.35.3.447-b  0.145
1983 Wong PT, McGeer EG, Singh K, McGeer PL. Changes in muscarinic binding in distant brain regions showing neuronal losses after folic acid injections into the substantia innominata. Journal of Neurochemistry. 40: 1754-7. PMID 6304254 DOI: 10.1111/J.1471-4159.1983.Tb08151.X  0.145
2009 Qing H, Zhang Y, Deng Y, McGeer EG, McGeer PL. Lrrk2 interaction with alpha-synuclein in diffuse Lewy body disease. Biochemical and Biophysical Research Communications. 390: 1229-34. PMID 19878656 DOI: 10.1016/J.Bbrc.2009.10.126  0.144
1994 Yamada T, Tsubouchi H, Daikuhara Y, Prat M, Comoglio PM, McGeer PL, McGeer EG. Immunohistochemistry with antibodies to hepatocyte growth factor and its receptor protein (c-MET) in human brain tissues. Brain Research. 637: 308-12. PMID 8180811  0.144
2016 Miklossy J, McGeer PL. Common mechanisms involved in Alzheimer's disease and type 2 diabetes: a key role of chronic bacterial infection and inflammation. Aging. PMID 26961231 DOI: 10.18632/aging.100921  0.144
1980 McGeer EG, McGeer PL, Hattori T, Singh VK. Immunohistochemistry of choline acetyltransferase. Progress in Brain Research. 49: 59-70. PMID 390613 DOI: 10.1016/S0079-6123(08)64621-X  0.143
1963 WADA JA, WRINCH J, HILL D, McGEER PL, McGEER EG. Central aromatic amine levels and behavior. I. Conditioned avoidance response in cats, following administration of psychoactive drugs or amine precursors. Archives of Neurology. 9: 69-80. PMID 13998142 DOI: 10.1001/Archneur.1963.00460070079008  0.142
1971 McGeer PL, McGeer EG, Wada JA. Glutamic acid decarboxylase in Parkinson's disease and epilepsy. Neurology. 21: 1000-7. PMID 5165300 DOI: 10.1212/Wnl.21.10.1000  0.141
1992 Yamada T, McGeer PL, McGeer EG. Lewy bodies in Parkinson's disease are recognized by antibodies to complement proteins. Acta Neuropathologica. 84: 100-4. PMID 1502878 DOI: 10.1007/Bf00427222  0.141
1997 Matsuo A, Lee GC, Terai K, Takami K, Hickey WF, McGeer EG, McGeer PL. Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens. The American Journal of Pathology. 150: 1253-66. PMID 9094982  0.138
1983 Noda Y, McGeer PL, McGeer EG. Lipid peroxide distribution in brain and the effect of hyperbaric oxygen. Journal of Neurochemistry. 40: 1329-32. PMID 6834064 DOI: 10.1111/J.1471-4159.1983.Tb13574.X  0.137
2008 Steele JC, McGeer PL. The ALS/PDC syndrome of Guam and the cycad hypothesis. Neurology. 70: 1984-90. PMID 18490618 DOI: 10.1212/01.wnl.0000312571.81091.26  0.137
1988 Mizukawa K, Vincent SR, McGeer PL, McGeer EG. Reduced nicotinamide adenine dinucleotide phosphate (NADPH)-diaphorase-positive neurons in cat cerebral white matter. Brain Research. 461: 274-81. PMID 3179718 DOI: 10.1016/0006-8993(88)90257-0  0.136
1987 Kamo H, Kim SU, McGeer PL, Shin DH. Functional recovery in a rat model of Parkinson's disease following transplantation of cultured human sympathetic neurons. Brain Research. 397: 372-6. PMID 2879605 DOI: 10.1016/0006-8993(86)90641-4  0.136
2008 McGeer PL. Amyloid-beta vaccination for Alzheimer's dementia. Lancet. 372: 1381; author reply 1. PMID 18940458 DOI: 10.1016/S0140-6736(08)61579-2  0.135
1986 McGeer PL, Kamo H, Harrop R, McGeer EG, Martin WR, Pate BD, Li DK. Comparison of PET, MRI, and CT with pathology in a proven case of Alzheimer's disease. Neurology. 36: 1569-74. PMID 3491344 DOI: 10.1212/Wnl.36.12.1569  0.134
1989 Walker DG, Itagaki S, Berry K, McGeer PL. Examination of brains of AIDS cases for human immunodeficiency virus and human cytomegalovirus nucleic acids. Journal of Neurology, Neurosurgery, and Psychiatry. 52: 583-90. PMID 2543795 DOI: 10.1136/jnnp.52.5.583  0.134
1972 MacFadyen DJ, Picton TW, Zeldowicz L, McGeer PL. Amantadine-HCl in the treatment of Parkinson's disease: a controlled trial. The Journal of Clinical Pharmacology and New Drugs. 12: 274-9. PMID 4483534  0.133
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