Albért Hofman, MD - Publications

Affiliations: 
Epidemiology and Biostatistics Erasmus Medical Center Rotterdam, Rotterdam, Netherlands 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=31
Website:
http://www.hsph.harvard.edu/faculty/albert-hofman/

500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lagou V, Jiang L, Ulrich A, Zudina L, González KSG, Balkhiyarova Z, Faggian A, Maina JG, Chen S, Todorov PV, Sharapov S, David A, Marullo L, Mägi R, Rujan RM, ... ... Hofman A, et al. GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification. Nature Genetics. 55: 1448-1461. PMID 37679419 DOI: 10.1038/s41588-023-01462-3  0.319
2022 Waziry R, Hofman A, Ghanbari M, Tiemeier H, Ikram MA, Viswanathan A, Klap J, Ikram MK, Goudsmit J. Biological aging for risk prediction of first-ever intracerebral hemorrhage and cerebral infarction in advanced age. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association. 31: 106568. PMID 35749936 DOI: 10.1016/j.jstrokecerebrovasdis.2022.106568  0.511
2021 Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L, ... ... Hofman A, et al. Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nature Communications. 12: 24. PMID 33402679 DOI: 10.1038/s41467-020-19366-9  0.326
2020 Hofer E, Roshchupkin GV, Adams HHH, Knol MJ, Lin H, Li S, Zare H, Ahmad S, Armstrong NJ, Satizabal CL, Bernard M, Bis JC, Gillespie NA, Luciano M, Mishra A, ... ... Hofman A, et al. Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nature Communications. 11: 4796. PMID 32963231 DOI: 10.1038/s41467-020-18367-y  0.392
2020 Zheng Y, Huang T, Wang T, Mei Z, Sun Z, Zhang T, Ellervik C, Chai JF, Sim X, van Dam RM, Tai ES, Koh WP, Dorajoo R, Saw SM, Sabanayagam C, ... ... Hofman A, et al. Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood. European Journal of Epidemiology. PMID 32383070 DOI: 10.1007/S10654-020-00638-Z  0.363
2020 de Wolf F, Ghanbari M, Licher S, McRae-McKee K, Gras L, Weverling GJ, Wermeling P, Sedaghat S, Ikram MK, Waziry R, Koudstaal W, Klap J, Kostense S, Hofman A, Anderson R, et al. Plasma tau, neurofilament light chain and amyloid-β levels and risk of dementia; a population-based cohort study. Brain : a Journal of Neurology. PMID 32206776 DOI: 10.1093/Brain/Awaa054  0.316
2019 Couto Alves A, De Silva NMG, Karhunen V, Sovio U, Das S, Taal HR, Warrington NM, Lewin AM, Kaakinen M, Cousminer DL, Thiering E, Timpson NJ, Bond TA, Lowry E, Brown CD, ... ... Hofman A, et al. GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. Science Advances. 5: eaaw3095. PMID 31840077 DOI: 10.1126/Sciadv.Aaw3095  0.451
2019 Ma Y, Song A, Viswanathan A, Blacker D, Vernooij MW, Hofman A, Papatheodorou S. Blood Pressure Variability and Cerebral Small Vessel Disease: A Systematic Review and Meta-Analysis of Population-Based Cohorts. Stroke. STROKEAHA119026739. PMID 31771460 DOI: 10.1161/Strokeaha.119.026739  0.357
2019 Ma Y, Wolters FJ, Chibnik LB, Licher S, Ikram MA, Hofman A, Ikram MK. Variation in blood pressure and long-term risk of dementia: A population-based cohort study. Plos Medicine. 16: e1002933. PMID 31714941 DOI: 10.1371/Journal.Pmed.1002933  0.319
2019 Ars CL, Nijs IM, Marroun HE, Muetzel R, Schmidt M, Steenweg-de Graaff J, van der Lugt A, Jaddoe VW, Hofman A, Steegers EA, Verhulst FC, Tiemeier H, White T. Prenatal folate, homocysteine and vitamin B levels and child brain volumes, cognitive development and psychological functioning: the Generation R Study. The British Journal of Nutrition. 122: S1-S9. PMID 31638501 DOI: 10.1017/S0007114515002081  0.634
2019 Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, ... ... Hofman A, et al. Genetic architecture of subcortical brain structures in 38,851 individuals. Nature Genetics. PMID 31636452 DOI: 10.1038/S41588-019-0511-Y  0.451
2019 Bahls M, Lorenz MW, Dörr M, Gao L, Kitagawa K, Tuomainen TP, Agewall S, Berenson G, Catapano AL, Norata GD, Bots ML, van Gilst W, Asselbergs FW, Brouwers FP, Uthoff H, ... ... Hofman A, et al. Progression of conventional cardiovascular risk factors and vascular disease risk in individuals: insights from the PROG-IMT consortium. European Journal of Preventive Cardiology. 2047487319877078. PMID 31619084 DOI: 10.1177/2047487319877078  0.314
2019 Wu L, Lin H, Hu Y, Zhu C, Ma H, Gao J, Wu J, Shen H, Jiang W, Zhao N, Yin Y, Pan B, Jeekel J, Hofman A, Gao X. The major causes and risk factors of total and cause-specific mortality during 5.4-year follow-up: the Shanghai Changfeng Study. European Journal of Epidemiology. PMID 31372866 DOI: 10.1007/S10654-019-00543-0  0.337
2019 Sung YJ, de Las Fuentes L, Winkler TW, Chasman DI, Bentley AR, Kraja AT, Ntalla I, Warren HR, Guo X, Schwander K, Manning AK, Brown MR, Aschard H, Feitosa MF, Franceschini N, ... ... Hofman A, et al. A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. Human Molecular Genetics. PMID 31127295 DOI: 10.1093/Hmg/Ddz070  0.447
2019 Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Ø, Laurin C, Bacelis J, Peng S, Hao K, Feenstra B, Wood AR, Mahajan A, Tyrrell J, Robertson NR, Rayner NW, ... ... Hofman A, et al. Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nature Genetics. PMID 31043758 DOI: 10.1038/S41588-019-0403-1  0.449
2019 Waziry R, Gras L, Sedaghat S, Tiemeier H, Weverling GJ, Ghanbari M, Klap J, de Wolf F, Hofman A, Ikram MA, Goudsmit J. Quantification of biological age as a determinant of age-related diseases in the Rotterdam Study: a structural equation modeling approach. European Journal of Epidemiology. PMID 30993509 DOI: 10.1007/S10654-019-00497-3  0.563
2019 Karasik D, Zillikens MC, Hsu YH, Aghdassi A, Akesson K, Amin N, Barroso I, Bennett DA, Bertram L, Bochud M, Borecki IB, Broer L, Buchman AS, Byberg L, Campbell H, ... ... Hofman A, et al. Disentangling the genetics of lean mass. The American Journal of Clinical Nutrition. PMID 30721968 DOI: 10.1093/Ajcn/Nqy272  0.412
2019 Licher S, Heshmatollah A, van der Willik KD, Stricker BHC, Ruiter R, de Roos EW, Lahousse L, Koudstaal PJ, Hofman A, Fani L, Brusselle GGO, Bos D, Arshi B, Kavousi M, Leening MJG, et al. Lifetime risk and multimorbidity of non-communicable diseases and disease-free life expectancy in the general population: A population-based cohort study. Plos Medicine. 16: e1002741. PMID 30716101 DOI: 10.1371/Journal.Pmed.1002741  0.327
2019 Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, ... ... Hofman A, et al. Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology. PMID 30651383 DOI: 10.1212/Wnl.0000000000006851  0.458
2019 Karlsson Linnér R, Biroli P, Kong E, Meddens SFW, Wedow R, Fontana MA, Lebreton M, Tino SP, Abdellaoui A, Hammerschlag AR, Nivard MG, Okbay A, Rietveld CA, Timshel PN, Trzaskowski M, ... ... Hofman A, et al. Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. Nature Genetics. PMID 30643258 DOI: 10.1038/S41588-018-0309-3  0.573
2018 Sabater-Lleal M, Huffman JE, de Vries PS, Marten J, Mastrangelo MA, Song C, Pankratz N, Ward-Caviness CK, Yanek LR, Trompet S, Delgado GE, Guo X, Bartz TM, Martinez-Perez A, Germain M, ... ... Hofman A, et al. Genome-Wide Association Trans-Ethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels. Circulation. PMID 30586737 DOI: 10.1161/Circulationaha.118.034532  0.309
2018 Franceschini N, Giambartolomei C, de Vries PS, Finan C, Bis JC, Huntley RP, Lovering RC, Tajuddin SM, Winkler TW, Graff M, Kavousi M, Dale C, Smith AV, Hofer E, van Leeuwen EM, ... ... Hofman A, et al. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nature Communications. 9: 5141. PMID 30510157 DOI: 10.1038/S41467-018-07340-5  0.471
2018 Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, ... ... Hofman A, et al. Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics. PMID 30429575 DOI: 10.1038/S41588-018-0297-3  0.418
2018 Iotchkova V, Huang J, Morris JA, Jain D, Barbieri C, Walter K, Min JL, Chen L, Astle W, Cocca M, Deelen P, Elding H, Farmaki AE, Franklin CS, Franberg M, ... ... Hofman A, et al. Author Correction: Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps. Nature Genetics. PMID 30390057 DOI: 10.1038/S41588-018-0276-8  0.438
2018 Ligthart S, Vaez A, Võsa U, Stathopoulou MG, de Vries PS, Prins BP, Van der Most PJ, Tanaka T, Naderi E, Rose LM, Wu Y, Karlsson R, Barbalic M, Lin H, Pool R, ... ... Hofman A, et al. Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. American Journal of Human Genetics. 103: 691-706. PMID 30388399 DOI: 10.1016/J.Ajhg.2018.09.009  0.31
2018 Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, ... ... Hofman A, et al. Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics. PMID 30224653 DOI: 10.1038/S41588-018-0205-X  0.426
2018 Ashar FN, Mitchell RN, Albert CM, Newton-Cheh C, Brody JA, Müller-Nurasyid M, Moes A, Meitinger T, Mak A, Huikuri H, Junttila MJ, Goyette P, Pulit SL, Pazoki R, Tanck MW, ... ... Hofman A, et al. A comprehensive evaluation of the genetic architecture of sudden cardiac arrest. European Heart Journal. PMID 30169657 DOI: 10.1093/Eurheartj/Ehy474  0.306
2018 Merino J, Dashti HS, Li SX, Sarnowski C, Justice AE, Graff M, Papoutsakis C, Smith CE, Dedoussis GV, Lemaitre RN, Wojczynski MK, Männistö S, Ngwa JS, Kho M, Ahluwalia TS, ... ... Hofman A, et al. Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. Molecular Psychiatry. PMID 29988085 DOI: 10.1038/S41380-018-0079-4  0.326
2018 Kieboom BCT, Hoorn EJ, Ramakers C, van Rooij FJA, Ikram MA, Hofman A, van Duijn CM, Heeringa J, Zietse R, Peeters RP, Stricker BH, de Rijke YB. Standard process-oriented workflow introduces pre-analytical error when used in large study sample batches. Clinical Chemistry and Laboratory Medicine. PMID 29858899 DOI: 10.1515/Cclm-2018-0295  0.368
2018 Tedja MS, Wojciechowski R, Hysi PG, Eriksson N, Furlotte NA, Verhoeven VJM, Iglesias AI, Meester-Smoor MA, Tompson SW, Fan Q, Khawaja AP, Cheng CY, Höhn R, Yamashiro K, Wenocur A, ... ... Hofman A, et al. Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error. Nature Genetics. PMID 29808027 DOI: 10.1038/s41588-018-0127-7  0.337
2018 Campos-Obando N, Lahousse L, Brusselle G, Stricker BH, Hofman A, Franco OH, Uitterlinden AG, Zillikens MC. Serum phosphate levels are related to all-cause, cardiovascular and COPD mortality in men. European Journal of Epidemiology. PMID 29766437 DOI: 10.1007/S10654-018-0407-7  0.325
2018 Dhana K, Braun KVE, Nano J, Voortman T, Demerath EW, Guan W, Fornage M, van Meurs JBJ, Uitterlinden AG, Hofman A, Franco OH, Dehghan A. An Epigenome-Wide Association Study (EWAS) of Obesity-Related Traits. American Journal of Epidemiology. PMID 29762635 DOI: 10.1093/Aje/Kwy025  0.308
2018 Amin N, de Vrij FMS, Baghdadi M, Brouwer RWW, van Rooij JGJ, Jovanova O, Uitterlinden AG, Hofman A, Janssen HLA, Murad SD, Kraaij R, Stedehouder J, van den Hout MCGN, Kros JM, van IJcken WFJ, et al. Employed family-based genetic discovery combining linkage analysis and exome sequencing to identify RCL1 as a novel candidate gene for depression, with independent replication in a population-based cohort. Molecular Psychiatry. 23: 1093. PMID 29731510 DOI: 10.1038/Mp.2018.6  0.539
2018 Corominas J, Colijn JM, Geerlings MJ, Pauper M, Bakker B, Amin N, Lores Motta L, Kersten E, Garanto A, Verlouw JAM, van Rooij JGJ, Kraaij R, de Jong PTVM, Hofman A, Vingerling JR, et al. Whole-Exome Sequencing in Age-Related Macular Degeneration Identifies Rare Variants in COL8A1, a Component of Bruch's Membrane. Ophthalmology. PMID 29706360 DOI: 10.1016/J.Ophtha.2018.03.040  0.459
2018 van der Lee SJ, Wolters FJ, Ikram MK, Hofman A, Ikram MA, Amin N, van Duijn CM. The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study. The Lancet. Neurology. PMID 29555425 DOI: 10.1016/S1474-4422(18)30053-X  0.465
2018 Sung YJ, Winkler TW, de Las Fuentes L, Bentley AR, Brown MR, Kraja AT, Schwander K, Ntalla I, Guo X, Franceschini N, Lu Y, Cheng CY, Sim X, Vojinovic D, Marten J, ... ... Hofman A, et al. A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. American Journal of Human Genetics. PMID 29455858 DOI: 10.1016/J.Ajhg.2018.01.015  0.473
2018 Gotink RA, Vernooij MW, Ikram MA, Niessen WJ, Krestin GP, Hofman A, Tiemeier H, Hunink MGM. Meditation and yoga practice are associated with smaller right amygdala volume: the Rotterdam study. Brain Imaging and Behavior. PMID 29417491 DOI: 10.1007/S11682-018-9826-Z  0.544
2018 Beaumont RN, Warrington NM, Cavadino A, Tyrrell J, Nodzenski M, Horikoshi M, Geller F, Myhre R, Richmond RC, Paternoster L, Bradfield JP, Kreiner-Møller E, Huikari V, Metrustry S, Lunetta KL, ... ... Hofman A, et al. Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Human Molecular Genetics. PMID 29309628 DOI: 10.1093/Hmg/Ddx429  0.309
2018 de Vrij FM, Bouwkamp CG, Gunhanlar N, Shpak G, Lendemeijer B, Baghdadi M, Gopalakrishna S, Ghazvini M, Li TM, Quadri M, Olgiati S, Breedveld GJ, Coesmans M, Mientjes E, de Wit T, ... ... Hofman A, et al. Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia. Molecular Psychiatry. PMID 29302076 DOI: 10.1038/S41380-017-0004-2  0.581
2018 Shevroja E, Koromani F, Muka T, Oei L, Zillikens C, Hofman A, Uitterlinden AG, Oei E, Hans D, Franco OH, Rivadeneira F. Sex Hormone-Binding Globulin Is Associated With Markers Of Vertebral Fracture And Vertebral Fracture Risk Journal of Clinical Densitometry. 21: 609-610. DOI: 10.1016/J.Jocd.2018.05.033  0.343
2017 Vibha D, Tiemeier H, Mirza SS, Adams HHH, Niessen WJ, Hofman A, Prasad K, van der Lugt A, Vernooij MW, Ikram MA. Brain Volumes and Longitudinal Cognitive Change: A Population-based Study. Alzheimer Disease and Associated Disorders. PMID 29278559 DOI: 10.1097/Wad.0000000000000235  0.54
2017 Freak-Poli R, Ikram MA, Franco OH, Hofman A, Tiemeier H. Depressive symptoms prior to and after incident cardiovascular disease and long-term survival. A population-based study of older persons. Depression and Anxiety. PMID 29172249 DOI: 10.1002/Da.22689  0.546
2017 Pavlović J, Greenland P, Deckers JW, Kavousi M, Hofman A, Ikram MA, Franco OH, Leening MJ. Assessing gaps in cholesterol treatment guidelines for primary prevention of cardiovascular disease based on available randomised clinical trial evidence: The Rotterdam Study. European Journal of Preventive Cardiology. 2047487317743352. PMID 29171772 DOI: 10.1177/2047487317743352  0.307
2017 Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, ... ... Hofman A, et al. Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nature Communications. 8: 1414. PMID 29116125 DOI: 10.1038/s41467-017-01008-2  0.344
2017 Mirza SS, Ikram MA, Freak-Poli R, Hofman A, Rizopoulos D, Tiemeier H. 12-year trajectories of depressive symptoms in community-dwelling older adults and the subsequent risk of death over 13 years. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 29099907 DOI: 10.1093/Gerona/Glx215  0.542
2017 van der Spek A, Luik AI, Kocevska D, Liu C, Brouwer RWW, van Rooij JGJ, van den Hout MCGN, Kraaij R, Hofman A, Uitterlinden AG, van IJcken WFJ, Gottlieb DJ, Tiemeier H, van Duijn CM, Amin N. Exome-Wide Meta-Analysis Identifies Rare 3'-UTR Variant in ERCC1/CD3EAP Associated with Symptoms of Sleep Apnea. Frontiers in Genetics. 8: 151. PMID 29093733 DOI: 10.3389/Fgene.2017.00151  0.606
2017 Ikram MA, Brusselle GGO, Murad SD, van Duijn CM, Franco OH, Goedegebure A, Klaver CCW, Nijsten TEC, Peeters RP, Stricker BH, Tiemeier H, Uitterlinden AG, Vernooij MW, Hofman A. The Rotterdam Study: 2018 update on objectives, design and main results. European Journal of Epidemiology. PMID 29064009 DOI: 10.1007/S10654-017-0321-4  0.619
2017 Chibnik LB, Wolters FJ, Bäckman K, Beiser A, Berr C, Bis JC, Boerwinkle E, Bos D, Brayne C, Dartigues JF, Darweesh SKL, Debette S, Davis-Plourde KL, Dufouil C, Fornage M, ... ... Hofman A, et al. Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium. European Journal of Epidemiology. PMID 29063414 DOI: 10.1007/S10654-017-0320-5  0.337
2017 Strawbridge RJ, Silveira A, Hoed MD, Gustafsson S, Luan J, Rybin D, Dupuis J, Li-Gao R, Kavousi M, Dehghan A, Haljas K, Lahti J, Gådin JR, Bäcklund A, de Faire U, ... ... Hofman A, et al. Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation. Atherosclerosis. 266: 196-204. PMID 29040868 DOI: 10.1016/J.Atherosclerosis.2017.09.031  0.352
2017 Hollander WD, Boer CG, Hart DJ, Yau MS, Ramos YFM, Metrustry S, Broer L, Deelen J, Cupples LA, Rivadeneira F, Kloppenburg M, Peters M, Spector TD, Hofman A, Slagboom PE, et al. Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand. Annals of the Rheumatic Diseases. PMID 28855172 DOI: 10.1136/Annrheumdis-2017-211214  0.304
2017 Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, ... ... Hofman A, et al. Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Plos Genetics. 13: e1006972. PMID 28832619 DOI: 10.1371/Journal.Pgen.1006972  0.395
2017 Ham AC, Aarts N, Noordam R, Rivadeneira F, Ziere G, Zillikens MC, Tiemeier H, van der Velde N, Hofman A, Uitterlinden AG, Visser LE, Stricker BH. Use of Selective Serotonin Reuptake Inhibitors and Bone Mineral Density Change: A Population-Based Longitudinal Study in Middle-Aged and Elderly Individuals. Journal of Clinical Psychopharmacology. PMID 28816927 DOI: 10.1097/Jcp.0000000000000756  0.516
2017 Christophersen IE, Magnani JW, Yin X, Barnard J, Weng LC, Arking DE, Niemeijer MN, Lubitz SA, Avery CL, Duan Q, Felix SB, Bis JC, Kerr KF, Isaacs A, Müller-Nurasyid M, ... ... Hofman A, et al. Fifteen Genetic Loci Associated With the Electrocardiographic P Wave. Circulation. Cardiovascular Genetics. 10. PMID 28794112 DOI: 10.1161/Circgenetics.116.001667  0.415
2017 Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, ... ... Hofman A, et al. Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nature Communications. 8: 16140. PMID 28767105 DOI: 10.1038/Ncomms16140  0.537
2017 Yano Y, O'Donnell CJ, Kuller L, Kavousi M, Erbel R, Ning H, D'Agostino R, Newman AB, Nasir K, Hofman A, Lehmann N, Dhana K, Blankstein R, Hoffmann U, Möhlenkamp S, et al. Association of Coronary Artery Calcium Score vs Age With Cardiovascular Risk in Older Adults: An Analysis of Pooled Population-Based Studies. Jama Cardiology. PMID 28746709 DOI: 10.1001/Jamacardio.2017.2498  0.317
2017 Wain LV, Vaez A, Jansen R, Joehanes R, van der Most PJ, Erzurumluoglu AM, O'Reilly PF, Cabrera CP, Warren HR, Rose LM, Verwoert GC, Hottenga JJ, Strawbridge RJ, Esko T, Arking DE, ... ... Hofman A, et al. Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Hypertension (Dallas, Tex. : 1979). PMID 28739976 DOI: 10.1161/Hypertensionaha.117.09438  0.44
2017 Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, ... ... Hofman A, et al. Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nature Communications. 8: 80. PMID 28724990 DOI: 10.1038/S41467-017-00031-7  0.431
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Hofman A, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.627
2017 van der Knaap NJF, Klumpers F, El Marroun H, Mous S, Schubert D, Jaddoe V, Hofman A, Homberg JR, Tiemeier H, White T, Fernández G. Maternal depressive symptoms during pregnancy are associated with amygdala hyperresponsivity in children. European Child & Adolescent Psychiatry. PMID 28667426 DOI: 10.1007/S00787-017-1015-X  0.56
2017 Urbano L, Portilla E, Muñoz W, Hofman A, Sierra-Torres CH. Prevalence and risk factors associated to peripheral arterial disease in an adult population from Colombia. Archivos De Cardiologia De Mexico. PMID 28623035 DOI: 10.1016/J.Acmx.2017.02.002  0.305
2017 Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, ... ... Hofman A, et al. Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nature Communications. 8: 15805. PMID 28613276 DOI: 10.1038/Ncomms15805  0.556
2017 Springelkamp H, Wolfs RC, Ramdas WD, Hofman A, Vingerling JR, Klaver CC, Jansonius NM. Incidence of glaucomatous visual field loss after two decades of follow-up: the Rotterdam Study. European Journal of Epidemiology. PMID 28608186 DOI: 10.1007/S10654-017-0270-Y  0.34
2017 Tideman JWL, Polling JR, Hofman A, Jaddoe VW, Mackenbach JP, Klaver CC. Environmental factors explain socioeconomic prevalence differences in myopia in 6-year-old children. The British Journal of Ophthalmology. PMID 28607175 DOI: 10.1136/Bjophthalmol-2017-310292  0.301
2017 Wolters FJ, Zonneveld HI, Hofman A, van der Lugt A, Koudstaal PJ, Vernooij MW, Ikram MA. Cerebral Perfusion and the Risk of Dementia: A Population-Based Study. Circulation. PMID 28588075 DOI: 10.1161/Circulationaha.117.027448  0.353
2017 Holstege H, van der Lee SJ, Hulsman M, Wong TH, van Rooij JG, Weiss M, Louwersheimer E, Wolters FJ, Amin N, Uitterlinden AG, Hofman A, Ikram MA, van Swieten JC, Meijers-Heijboer H, van der Flier WM, et al. Characterization of pathogenic SORL1 genetic variants for association with Alzheimer's disease: a clinical interpretation strategy. European Journal of Human Genetics : Ejhg. PMID 28537274 DOI: 10.1038/Ejhg.2017.87  0.477
2017 Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, ... ... Hofman A, et al. Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. Plos Genetics. 13: e1006528. PMID 28448500 DOI: 10.1371/Journal.Pgen.1006528  0.435
2017 Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, Lin H, Arking DE, Smith AV, Albert CM, Chaffin M, Tucker NR, Li M, Klarin D, Bihlmeyer NA, ... ... Hofman A, et al. Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nature Genetics. PMID 28416818 DOI: 10.1038/Ng.3843  0.308
2017 van 't Hof FN, Vaucher J, Holmes MV, de Wilde A, Baas AF, Blankensteijn JD, Hofman A, Kiemeney LA, Rivadeneira F, Uitterlinden AG, Vermeulen SH, Rinkel GJ, de Bakker PI, Ruigrok YM. Genetic variants associated with type 2 diabetes and adiposity and risk of intracranial and abdominal aortic aneurysms. European Journal of Human Genetics : Ejhg. PMID 28378816 DOI: 10.1038/Ejhg.2017.48  0.334
2017 Böger CA, Gorski M, McMahon GM, Xu H, Chang YC, van der Most PJ, Navis G, Nolte IM, de Borst MH, Zhang W, Lehne B, Loh M, Tan ST, Boerwinkle E, Grams ME, ... ... Hofman A, et al. NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality. Journal of the American Society of Nephrology : Jasn. PMID 28360221 DOI: 10.1681/Asn.2016080892  0.303
2017 Wolters FJ, van der Lee SJ, Koudstaal PJ, van Duijn CM, Hofman A, Ikram MK, Vernooij MW, Ikram MA. Parental family history of dementia in relation to subclinical brain disease and dementia risk. Neurology. PMID 28356461 DOI: 10.1212/Wnl.0000000000003871  0.464
2017 Amin N, de Vrij FM, Baghdadi M, Brouwer RW, van Rooij JG, Jovanova O, Uitterlinden AG, Hofman A, Janssen HL, Darwish Murad S, Kraaij R, Stedehouder J, van den Hout MC, Kros JM, van IJcken WF, et al. A rare missense variant in RCL1 segregates with depression in extended families. Molecular Psychiatry. PMID 28322274 DOI: 10.1038/Mp.2017.49  0.556
2017 Sajjad A, Freak-Poli RL, Hofman A, Roza SJ, Ikram MA, Tiemeier H. Subjective measures of health and all-cause mortality - the Rotterdam Study. Psychological Medicine. 1-10. PMID 28287059 DOI: 10.1017/S0033291717000381  0.496
2017 Muka T, Nano J, Jaspers L, Meun C, Bramer WM, Hofman A, Dehghan A, Kavousi M, Laven JS, Franco OH. Associations of Steroid Sex Hormones and Sex Hormone-Binding Globulin With the Risk of Type 2 Diabetes in Women: A Population-Based Cohort Study and Meta-analysis. Diabetes. 66: 577-586. PMID 28223343 DOI: 10.2337/Db16-0473  0.336
2017 Grootendorst-van Mil NH, Steegers-Theunissen RP, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Brighter children? The association between seasonality of birth and child IQ in a population-based birth cohort. Bmj Open. 7: e012406. PMID 28213594 DOI: 10.1136/Bmjopen-2016-012406  0.632
2017 Campos-Obando N, Koek WN, Hooker ER, van der Eerden BC, Pols HA, Hofman A, van Leeuwen JP, Uitterlinden AG, Nielson CM, Zillikens MC. Serum Phosphate Is Associated with Fracture Risk: The Rotterdam Study and MrOS. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28177140 DOI: 10.1002/Jbmr.3094  0.32
2017 Verlinden VJ, van der Geest JN, Hofman A, Niessen WJ, van der Lugt A, Vernooij MW, Ikram MA. Brain MRI-markers Associate Differentially with Cognitive Versus Functional Decline Leading to Dementia. Journal of the American Geriatrics Society. PMID 28165615 DOI: 10.1111/Jgs.14775  0.304
2017 van der Lee SJ, Roshchupkin GV, Adams HH, Schmidt H, Hofer E, Saba Y, Schmidt R, Hofman A, Amin N, van Duijn CM, Vernooij MW, Ikram MA, Niessen WJ. Gray matter heritability in family-based and population-based studies using voxel-based morphometry. Human Brain Mapping. PMID 28145022 DOI: 10.1002/Hbm.23528  0.419
2017 Jovanova O, Aarts N, Noordam R, Zillikens MC, Hofman A, Tiemeier H. Vitamin D serum levels are cross-sectionally but not prospectively associated with late-life depression. Acta Psychiatrica Scandinavica. 135: 185-194. PMID 28120398 DOI: 10.1111/acps.12689  0.473
2017 Joachim N, Colijn JM, Kifley A, Lee KE, Buitendijk GH, Klein BE, Myers CE, Meuer SM, Tan AG, Holliday EG, Attia J, Liew G, Iyengar SK, de Jong PT, Hofman A, et al. Five-year progression of unilateral age-related macular degeneration to bilateral involvement: the Three Continent AMD Consortium report. The British Journal of Ophthalmology. PMID 28108569 DOI: 10.1136/Bjophthalmol-2016-309729  0.304
2017 Milic J, Saavedra Perez H, Zuurbier LA, Boelen PA, Rietjens JA, Hofman A, Tiemeier H. The Longitudinal and Cross-Sectional Associations of Grief and Complicated Grief With Sleep Quality in Older Adults. Behavioral Sleep Medicine. 1-12. PMID 28107032 DOI: 10.1080/15402002.2016.1276016  0.502
2017 Freak-Poli R, Castro Lima G, Direk N, Jaspers L, Pitts M, Hofman A, Tiemeier H. Corrigendum: Happiness, rather than depression, is associated with sexual behaviour in partnered older adults. Age and Ageing. PMID 28104603 DOI: 10.1093/Ageing/Afx015  0.509
2017 Hibar DP, Adams HH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, ... ... Hofman A, et al. Novel genetic loci associated with hippocampal volume. Nature Communications. 8: 13624. PMID 28098162 DOI: 10.1038/Ncomms13624  0.474
2017 Pardo LM, Li WQ, Hwang SJ, Verkouteren JA, Hofman A, Uitterlinden AG, Kraft P, Turman C, Han J, Cho E, Murabito JM, Levy D, Qureshi AA, Nijsten T. Genome-Wide Association Studies of Multiple Keratinocyte Cancers. Plos One. 12: e0169873. PMID 28081215 DOI: 10.1371/Journal.Pone.0169873  0.324
2017 Springelkamp H, Iglesias AI, Mishra A, Höhn R, Wojciechowski R, Khawaja AP, Nag A, Wang YX, Wang JJ, Cuellar-Partida G, Gibson J, Cooke Bailey JN, Vithana EN, Gharahkhani P, Boutin T, ... ... Hofman A, et al. New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics. Human Molecular Genetics. PMID 28073927 DOI: 10.1093/Hmg/Ddw399  0.449
2017 Warner SC, van Meurs JB, Schiphof D, Bierma-Zeinstra SM, Hofman A, Uitterlinden AG, Richardson H, Jenkins W, Doherty M, Valdes AM. Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene. European Journal of Human Genetics : Ejhg. PMID 28051079 DOI: 10.1038/Ejhg.2016.196  0.311
2017 Jansen PW, Zwirs B, Verlinden M, Mieloo CL, Jaddoe VWV, Hofman A, Verhulst FC, Jansen W, van Ijzendoorn MH, Tiemeier H. Observed and parent-reported conscience in childhood: Relations with bullying involvement in early primary school Social Development. 26: 965-980. DOI: 10.1111/Sode.12233  0.599
2016 Zuurbier LA, Vernooij MW, Luik AI, Kocevska D, Hofman A, Whitmore H, Ikram MA, Tiemeier H. Apnea-hypopnea index, nocturnal arousals, oxygen desaturation and structural brain changes: A population-based study Neurobiology of Sleep and Circadian Rhythms. 1: 1-7. PMID 31236490 DOI: 10.1016/J.Nbscr.2016.04.001  0.525
2016 Ikram MA, Vernooij MW, Roshchupkin GV, Hofman A, van Duijn CM, Uitterlinden AG, Niessen WJ, Hintzen RQ, Adams HH. Genetic susceptibility to multiple sclerosis: Brain structure and cognitive function in the general population. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458516682104. PMID 28273768 DOI: 10.1177/1352458516682104  0.443
2016 Freak-Poli R, De Castro Lima G, Direk N, Jaspers L, Pitts M, Hofman A, Tiemeier H. Happiness, rather than depression, is associated with sexual behaviour in partnered older adults. Age and Ageing. PMID 28104602 DOI: 10.1093/Ageing/Afw168  0.499
2016 Direk N, Williams S, Smith JA, Ripke S, Air T, Amare AT, Amin N, Baune BT, Bennett DA, Blackwood DH, Boomsma D, Breen G, Buttenschøn HN, Byrne EM, Børglum AD, ... ... Hofman A, et al. An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype. Biological Psychiatry. PMID 28049566 DOI: 10.1016/J.Biopsych.2016.11.013  0.613
2016 Noordam R, Sitlani CM, Avery CL, Stewart JD, Gogarten SM, Wiggins KL, Trompet S, Warren HR, Sun F, Evans DS, Li X, Li J, Smith AV, Bis JC, Brody JA, ... ... Hofman A, et al. A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Journal of Medical Genetics. PMID 28039329 DOI: 10.1136/Jmedgenet-2016-104112  0.323
2016 van Rooij FJ, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang LC, Schmidt H, Yang ML, Chen MH, Hayes J, Johnson AD, Yanek LR, Mueller C, ... ... Hofman A, et al. Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. American Journal of Human Genetics. PMID 28017375 DOI: 10.1016/J.Ajhg.2016.11.016  0.461
2016 Wahl S, Drong A, Lehne B, Loh M, Scott WR, Kunze S, Tsai PC, Ried JS, Zhang W, Yang Y, Tan S, Fiorito G, Franke L, Guarrera S, Kasela S, ... ... Hofman A, et al. Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. Nature. PMID 28002404 DOI: 10.1038/Nature20784  0.448
2016 Roshchupkin GV, Gutman BA, Vernooij MW, Jahanshad N, Martin NG, Hofman A, McMahon KL, van der Lee SJ, van Duijn CM, de Zubicaray GI, Uitterlinden AG, Wright MJ, Niessen WJ, Thompson PM, Ikram MA, et al. Heritability of the shape of subcortical brain structures in the general population. Nature Communications. 7: 13738. PMID 27976715 DOI: 10.1038/Ncomms13738  0.429
2016 Koolhaas CM, Dhana K, van Rooij FJ, Kocevska D, Hofman A, Franco OH, Tiemeier H. Sedentary time assessed by actigraphy and mortality: The Rotterdam Study. Preventive Medicine. PMID 27939262 DOI: 10.1016/J.Ypmed.2016.11.021  0.555
2016 Chaker L, Sedaghat S, Hoorn EJ, Elzen WP, Gussekloo J, Hofman A, Ikram MA, Franco OH, Dehghan A, Peeters RP. The association of thyroid function and the risk of kidney function decline: a population-based cohort study. European Journal of Endocrinology. 175: 653-660. PMID 27926474 DOI: 10.1530/Eje-16-0537  0.302
2016 Zonneveld HI, Ikram MA, Hofman A, Niessen WJ, van der Lugt A, Krestin GP, Franco OH, Vernooij MW. N-Terminal Pro-B-Type Natriuretic Peptide and Subclinical Brain Damage in the General Population. Radiology. 160548. PMID 27924720 DOI: 10.1148/Radiol.2016160548  0.336
2016 Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman JE, Tromp G, Fuchsberger C, Gorski M, Lyytikäinen LP, Nutile T, Sedaghat S, Sorice R, Tin A, Yang Q, ... ... Hofman A, et al. SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. Journal of the American Society of Nephrology : Jasn. PMID 27920155 DOI: 10.1681/Asn.2016020131  0.317
2016 Bonder MJ, Luijk R, Zhernakova DV, Moed M, Deelen P, Vermaat M, van Iterson M, van Dijk F, van Galen M, Bot J, Slieker RC, Jhamai PM, Verbiest M, Suchiman HE, Verkerk M, ... ... Hofman A, et al. Disease variants alter transcription factor levels and methylation of their binding sites. Nature Genetics. PMID 27918535 DOI: 10.1038/Ng.3721  0.448
2016 Zhernakova DV, Deelen P, Vermaat M, van Iterson M, van Galen M, Arindrarto W, van 't Hof P, Mei H, van Dijk F, Westra HJ, Bonder MJ, van Rooij J, Verkerk M, Jhamai PM, Moed M, ... ... Hofman A, et al. Identification of context-dependent expression quantitative trait loci in whole blood. Nature Genetics. PMID 27918533 DOI: 10.1038/Ng.3737  0.464
2016 Schumann G, Liu C, O'Reilly P, Gao H, Song P, Xu B, Ruggeri B, Amin N, Jia T, Preis S, Segura Lepe M, Akira S, Barbieri C, Baumeister S, Cauchi S, ... ... Hofman A, et al. KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911795 DOI: 10.1073/Pnas.1611243113  0.39
2016 Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... Hofman A, et al. Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. 48: 1591. PMID 27898078 DOI: 10.1038/Ng1216-1587B  0.606
2016 Ham AC, Ziere G, Broer L, Swart KM, Enneman AW, van Dijk SC, van Wijngaarden JP, van der Zwaluw NL, Brouwer-Brolsma EM, Dhonukshe-Rutten RA, van Schoor NM, Zillikens MC, van Gelder T, de Vries OJ, Lips P, ... ... Hofman A, et al. CYP2C9 Genotypes Modify Benzodiazepine-Related Fall Risk: Original Results From Three Studies With Meta-Analysis. Journal of the American Medical Directors Association. PMID 27889507 DOI: 10.1016/J.Jamda.2016.09.021  0.315
2016 Saavedra Pérez HC, Direk N, Milic J, Ikram MA, Hofman A, Tiemeier H. The Impact of Complicated Grief on Diurnal Cortisol Levels Two Years After Loss: A Population-Based Study. Psychosomatic Medicine. PMID 27879552 DOI: 10.1097/Psy.0000000000000422  0.539
2016 Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G, Eklund N, Eriksson J, Esko T, Feitosa MF, Goel A, Gorski M, Hayward C, ... ... Hofman A, et al. A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nature Communications. 7: 13357. PMID 27876822 DOI: 10.1038/Ncomms13357  0.445
2016 Natarajan P, Bis JC, Bielak LF, Cox AJ, Dörr M, Feitosa MF, Franceschini N, Guo X, Hwang SJ, Isaacs A, Jhun MA, Kavousi M, Li-Gao R, Lyytikäinen LP, Marioni RE, ... ... Hofman A, et al. Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis. Circulation. Cardiovascular Genetics. PMID 27872105 DOI: 10.1161/Circgenetics.116.001572  0.479
2016 Selwaness M, Hameeteman R, Van 't Klooster R, Van den Bouwhuijsen Q, Hofman A, Franco OH, Niessen WJ, Klein S, Vernooij MW, Van der Lugt A, Wentzel JJ. Determinants of carotid atherosclerotic plaque burden in a stroke-free population. Atherosclerosis. PMID 27806835 DOI: 10.1016/J.Atherosclerosis.2016.10.030  0.302
2016 Barban N, Jansen R, de Vlaming R, Vaez A, Mandemakers JJ, Tropf FC, Shen X, Wilson JF, Chasman DI, Nolte IM, Tragante V, van der Laan SW, Perry JR, Kong A, ... ... Hofman A, et al. Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Nature Genetics. PMID 27798627 DOI: 10.1038/Ng.3698  0.484
2016 Latsuzbaia A, Jaddoe VW, Hofman A, Franco OH, Felix JF. Associations of genetic variants for adult lipid levels with lipid levels in children. The Generation R Study. Journal of Lipid Research. PMID 27777320 DOI: 10.1194/Jlr.P066902  0.317
2016 Wolters FJ, Bos D, Vernooij MW, Franco OH, Hofman A, Koudstaal PJ, van der Lugt A, Ikram MA. Aortic Valve Calcification and the Risk of dementia: A Population-Based Study. Journal of Alzheimer's Disease : Jad. PMID 27767996 DOI: 10.3233/Jad-160871  0.333
2016 Jakobsdottir J, van der Lee SJ, Bis JC, Chouraki V, Li-Kroeger D, Yamamoto S, Grove ML, Naj A, Vronskaya M, Salazar JL, DeStefano AL, Brody JA, Smith AV, Amin N, Sims R, ... ... Hofman A, et al. Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease. Plos Genetics. 12: e1006327. PMID 27764101 DOI: 10.1371/Journal.Pgen.1006327  0.475
2016 Amin N, Belonogova NM, Jovanova O, Brouwer RW, van Rooij JG, van den Hout MC, Svishcheva GR, Kraaij R, Zorkoltseva IV, Kirichenko AV, Hofman A, Uitterlinden AG, van IJcken WF, Tiemeier H, Axenovich TI, et al. Nonsynonymous Variation in NKPD1 Increases Depressive Symptoms in the European Populations. Biological Psychiatry. PMID 27745872 DOI: 10.1016/J.Biopsych.2016.08.008  0.616
2016 Dhana K, Koolhaas CM, Berghout MA, Peeters A, Ikram MA, Tiemeier H, Hofman A, Nusselder W, Franco OH. Physical activity types and life expectancy with and without cardiovascular disease: the Rotterdam Study. Journal of Public Health (Oxford, England). PMID 27738126 DOI: 10.1093/Pubmed/Fdw110  0.508
2016 Direk N, Dekker MJ, Luik AI, Kirschbaum C, de Rijke YB, Hofman A, Hoogendijk WJ, Tiemeier H. The Very Low-Dose Dexamethasone Suppression Test in the General Population: A Cross-Sectional Study. Plos One. 11: e0164348. PMID 27736954 DOI: 10.1371/Journal.Pone.0164348  0.554
2016 Wolters FJ, Mattace-Raso FU, Koudstaal PJ, Hofman A, Ikram MA. Orthostatic Hypotension and the Long-Term Risk of Dementia: A Population-Based Study. Plos Medicine. 13: e1002143. PMID 27727284 DOI: 10.1016/J.Jalz.2016.06.444  0.323
2016 Roshchupkin GV, Adams HH, van der Lee SJ, Vernooij MW, van Duijn CM, Uitterlinden AG, van der Lugt A, Hofman A, Niessen WJ, Ikram MA. Fine-mapping the effects of Alzheimer's disease risk loci on brain morphology. Neurobiology of Aging. 48: 204-211. PMID 27718423 DOI: 10.1016/J.Neurobiolaging.2016.08.024  0.477
2016 Evans TE, O'Sullivan MJ, de Groot M, Niessen WJ, Hofman A, Krestin GP, van der Lugt A, Portegies ML, Koudstaal PJ, Bos D, Vernooij MW, Ikram MA. White Matter Microstructure Improves Stroke Risk Prediction in the General Population. Stroke; a Journal of Cerebral Circulation. PMID 27703085 DOI: 10.1161/Strokeaha.116.014651  0.316
2016 Castaño-Betancourt MC, Evans DS, Ramos YF, Boer CG, Metrustry S, Liu Y, den Hollander W, van Rooij J, Kraus VB, Yau MS, Mitchell BD, Muir K, Hofman A, Doherty M, Doherty S, et al. Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis. Plos Genetics. 12: e1006260. PMID 27701424 DOI: 10.1371/Journal.Pgen.1006260  0.328
2016 Hosnijeh FS, Zuiderwijk ME, Versteeg M, Smeele HT, Hofman A, Uitterlinden AG, Agricola R, Oei EH, Waarsing JH, Bierma-Zeinstra SM, van Meurs JB. Cam deformity and acetabular dysplasia as risk factors for hip osteoarthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 27696746 DOI: 10.1002/Art.39929  0.314
2016 Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, ... ... Hofman A, et al. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience. PMID 27694991 DOI: 10.1038/Nn.4398  0.782
2016 Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca-Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, ... ... Hofman A, et al. Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nature Genetics. 48: 1296. PMID 27681292 DOI: 10.1038/Ng1016-1296C  0.427
2016 Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, van Zuydam NR, Gaulton KJ, Grarup N, Bradfield JP, Strachan DP, Li-Gao R, Ahluwalia TS, Kreiner E, ... ... Hofman A, et al. Genome-wide associations for birth weight and correlations with adult disease. Nature. PMID 27680694 DOI: 10.1038/Nature19806  0.497
2016 Iotchkova V, Huang J, Morris JA, Jain D, Barbieri C, Walter K, Min JL, Chen L, Astle W, Cocca M, Deelen P, Elding H, Farmaki AE, Franklin CS, Franberg M, ... ... Hofman A, et al. Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps. Nature Genetics. PMID 27668658 DOI: 10.1038/Ng.3668  0.476
2016 van der Harst P, van Setten J, Verweij N, Vogler G, Franke L, Maurano MT, Wang X, Mateo Leach I, Eijgelsheim M, Sotoodehnia N, Hayward C, Sorice R, Meirelles O, Lyytikäinen LP, Polašek O, ... ... Hofman A, et al. 52 Genetic Loci Influencing Myocardial Mass. Journal of the American College of Cardiology. 68: 1435-48. PMID 27659466 DOI: 10.1016/J.Jacc.2016.07.729  0.401
2016 Gheorghe M, Schurmann C, Peters MJ, Uitterlinden AG, Hofman A, Biffar R, Homuth G, Völker U, van Meurs JB, Raz V. Blood RNA expression profiles undergo major changes during the seventh decade. Oncotarget. PMID 27655681 DOI: 10.18632/Oncotarget.12098  0.31
2016 Slieker RC, van Iterson M, Luijk R, Beekman M, Zhernakova DV, Moed MH, Mei H, van Galen M, Deelen P, Bonder MJ, Zhernakova A, Uitterlinden AG, Tigchelaar EF, Stehouwer CD, Schalkwijk CG, ... ... Hofman A, et al. Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms. Genome Biology. 17: 191. PMID 27654999 DOI: 10.1186/S13059-016-1053-6  0.414
2016 Zhong K, Verkouteren JA, Jacobs LC, Uitterlinden AG, Hofman A, Liu F, Nijsten T, Kayser M. Pigmentation-Independent Susceptibility Loci for Actinic Keratosis Highlighted by Compound Heterozygosity Analysis. The Journal of Investigative Dermatology. PMID 27646882 DOI: 10.1016/J.Jid.2016.09.007  0.315
2016 Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Donnelly LA, Kanoni S, Petersen AK, Pihur V, Strawbridge RJ, Shungin D, Hughes MF, ... ... Hofman A, et al. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics. PMID 27618452 DOI: 10.1038/Ng.3667  0.45
2016 Khawaja AP, Springelkamp H, Creuzot-Garcher C, Delcourt C, Hofman A, Höhn R, Iglesias AI, Wolfs RC, Korobelnik JF, Silva R, Topouzis F, Williams KM, Bron AM, Buitendijk GH, Cachulo MD, et al. Associations with intraocular pressure across Europe: The European Eye Epidemiology (E(3)) Consortium. European Journal of Epidemiology. PMID 27613171 DOI: 10.1007/S10654-016-0191-1  0.486
2016 van der Plaat DA, de Jong K, Lahousse L, Faiz A, Vonk JM, van Diemen CC, Nedeljkovic I, Amin N, Brusselle GG, Hofman A, Brandsma CA, Bossé Y, Sin DD, Nickle DC, van Duijn CM, et al. Genome-wide association study on the FEV1/FVC-ratio in never-smokers identifies HHIP and FAM13A. The Journal of Allergy and Clinical Immunology. PMID 27612410 DOI: 10.1016/J.Jaci.2016.06.062  0.433
2016 Chaker L, van den Berg ME, Niemeijer MN, Franco OH, Dehghan A, Hofman A, Rijnbeek PR, Deckers JW, Eijgelsheim M, Stricker BH, Peeters RP. Thyroid Function and Sudden Cardiac Death: A Prospective Population-Based Cohort Study. Circulation. 134: 713-22. PMID 27601558 DOI: 10.1161/Circulationaha.115.020789  0.305
2016 Polfus LM, Khajuria RK, Schick UM, Pankratz N, Pazoki R, Brody JA, Chen MH, Auer PL, Floyd JS, Huang J, Lange L, van Rooij FJ, Gibbs RA, Metcalf G, Muzny D, ... ... Hofman A, et al. Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. American Journal of Human Genetics. 99: 785. PMID 27588453 DOI: 10.1016/J.Ajhg.2016.08.002  0.429
2016 Aarts N, Noordam R, Hofman A, Tiemeier H, Stricker BH, Visser LE. Self-reported indications for antidepressant use in a population-based cohort of middle-aged and elderly. International Journal of Clinical Pharmacy. PMID 27586370 DOI: 10.1007/S11096-016-0371-9  0.541
2016 Weiss A, Baselmans BM, Hofer E, Yang J, Okbay A, Lind PA, Miller MB, Nolte IM, Zhao W, Hagenaars SP, Hottenga JJ, Matteson LK, Snieder H, Faul JD, Hartman CA, ... ... Hofman A, et al. Personality Polygenes, Positive Affect, and Life Satisfaction. Twin Research and Human Genetics : the Official Journal of the International Society For Twin Studies. 1-11. PMID 27546527 DOI: 10.1017/Thg.2016.65  0.542
2016 Mirza SS, Ikram MA, Bos D, Mihaescu R, Hofman A, Tiemeier H. Mild cognitive impairment and risk of depression and anxiety: a population-based study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27520773 DOI: 10.1016/J.Jalz.2016.06.2361  0.541
2016 Zhou K, Yee SW, Seiser EL, van Leeuwen N, Tavendale R, Bennett AJ, Groves CJ, Coleman RL, van der Heijden AA, Beulens JW, de Keyser CE, Zaharenko L, Rotroff DM, Out M, Jablonski KA, ... ... Hofman A, et al. Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin. Nature Genetics. PMID 27500523 DOI: 10.1038/Ng.3632  0.303
2016 Polfus LM, Khajuria RK, Schick UM, Pankratz N, Pazoki R, Brody JA, Chen MH, Auer PL, Floyd JS, Huang J, Lange L, van Rooij FJ, Gibbs RA, Metcalf G, Muzny D, ... ... Hofman A, et al. Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. American Journal of Human Genetics. 99: 481-488. PMID 27486782 DOI: 10.1016/J.Ajhg.2016.06.016  0.448
2016 Okbay A, Baselmans BM, Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... Hofman A, et al. Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. 48: 970. PMID 27463399 DOI: 10.1038/ng0816-970c  0.588
2016 van Rheenen W, Shatunov A, Dekker AM, McLaughlin RL, Diekstra FP, Pulit SL, van der Spek RA, Võsa U, de Jong S, Robinson MR, Yang J, Fogh I, van Doormaal PT, Tazelaar GH, Koppers M, ... ... Hofman A, et al. Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. Nature Genetics. 48: 1043-8. PMID 27455348 DOI: 10.1038/Ng.3622  0.316
2016 Amin N, Jovanova O, Adams HH, Dehghan A, Kavousi M, Vernooij MW, Peeters RP, de Vrij FM, van der Lee SJ, van Rooij JG, van Leeuwen EM, Chaker L, Demirkan A, Hofman A, Brouwer RW, et al. Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms. Molecular Psychiatry. PMID 27431295 DOI: 10.1038/Mp.2016.101  0.57
2016 Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, ... ... Hofman A, et al. Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Plos Genetics. 12: e1006166. PMID 27355579 DOI: 10.1371/Journal.Pgen.1006166  0.35
2016 Dekkers KF, van Iterson M, Slieker RC, Moed MH, Bonder MJ, van Galen M, Mei H, Zhernakova DV, van den Berg LH, Deelen J, van Dongen J, van Heemst D, Hofman A, Hottenga JJ, van der Kallen CJ, et al. Blood lipids influence DNA methylation in circulating cells. Genome Biology. 17: 138. PMID 27350042 DOI: 10.1186/S13059-016-1000-6  0.397
2016 Tajuddin SM, Schick UM, Eicher JD, Chami N, Giri A, Brody JA, Hill WD, Kacprowski T, Li J, Lyytikäinen LP, Manichaikul A, Mihailov E, O'Donoghue ML, Pankratz N, Pazoki R, ... ... Hofman A, et al. Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases. American Journal of Human Genetics. PMID 27346689 DOI: 10.1016/J.Ajhg.2016.05.003  0.3
2016 Chami N, Chen MH, Slater AJ, Eicher JD, Evangelou E, Tajuddin SM, Love-Gregory L, Kacprowski T, Schick UM, Nomura A, Giri A, Lessard S, Brody JA, Schurmann C, Pankratz N, ... ... Hofman A, et al. Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. American Journal of Human Genetics. PMID 27346685 DOI: 10.1016/J.Ajhg.2016.05.007  0.474
2016 Chouraki V, Reitz C, Maury F, Bis JC, Bellenguez C, Yu L, Jakobsdottir J, Mukherjee S, Adams HH, Choi SH, Larson EB, Fitzpatrick A, Uitterlinden AG, de Jager PL, Hofman A, et al. Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27340842 DOI: 10.3233/Jad-150749  0.492
2016 Teumer A, Qi Q, Nethander M, Aschard H, Bandinelli S, Beekman M, Berndt SI, Bidlingmaier M, Broer L, Cappola A, Ceda GP, Chanock S, Chen MH, Chen TC, ... ... Hofman A, et al. Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. Aging Cell. PMID 27329260 DOI: 10.1111/Acel.12490  0.468
2016 Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca-Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, ... ... Hofman A, et al. Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nature Genetics. PMID 27322543 DOI: 10.1038/Ng.3598  0.482
2016 Zubakov D, Liu F, Kokmeijer I, Choi Y, van Meurs JB, van IJcken WF, Uitterlinden AG, Hofman A, Broer L, van Duijn CM, Lewin J, Kayser M. Human age estimation from blood using mRNA, DNA methylation, DNA rearrangement, and telomere length. Forensic Science International. Genetics. 24: 33-43. PMID 27288716 DOI: 10.1016/J.Fsigen.2016.05.014  0.428
2016 Akoudad S, Wolters FJ, Viswanathan A, de Bruijn RF, van der Lugt A, Hofman A, Koudstaal PJ, Ikram MA, Vernooij MW. Association of Cerebral Microbleeds With Cognitive Decline and Dementia. Jama Neurology. PMID 27271785 DOI: 10.1001/Jamaneurol.2016.1017  0.307
2016 Bergen NE, Schalekamp-Timmermans S, Jaddoe VW, Hofman A, Lindemans J, Russcher H, Tiemeier H, Steegers-Theunissen RP, Steegers EA. Maternal and Neonatal Markers of the Homocysteine Pathway and Fetal Growth: The Generation R Study. Paediatric and Perinatal Epidemiology. 30: 386-96. PMID 27271101 DOI: 10.1111/Ppe.12297  0.52
2016 Darweesh SK, Verlinden VJ, Adams HH, Uitterlinden AG, Hofman A, Stricker BH, van Duijn CM, Koudstaal PJ, Ikram MA. Genetic risk of Parkinson's disease in the general population. Parkinsonism & Related Disorders. PMID 27269966 DOI: 10.1016/J.Parkreldis.2016.05.030  0.464
2016 Direk N, Perez HS, Akoudad S, Verhaaren BF, Niessen WJ, Hofman A, Vernooij MW, Ikram MA, Tiemeier H. Markers of cerebral small vessel disease and severity of depression in the general population. Psychiatry Research. 253: 1-6. PMID 27254084 DOI: 10.1016/J.Pscychresns.2016.05.002  0.549
2016 Okbay A, Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P, Chen GB, Emilsson V, Meddens SF, Oskarsson S, Pickrell JK, Thom K, Timshel P, de Vlaming R, ... ... Hofman A, et al. Genome-wide association study identifies 74 loci associated with educational attainment. Nature. 533: 539-42. PMID 27225129 DOI: 10.1038/Nature17671  0.618
2016 Chen LY, Leening MJ, Norby FL, Roetker NS, Hofman A, Franco OH, Pan W, Polak JF, Witteman JC, Kronmal RA, Folsom AR, Nazarian S, Stricker BH, Heckbert SR, Alonso A. Carotid Intima-Media Thickness and Arterial Stiffness and the Risk of Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study, Multi-Ethnic Study of Atherosclerosis (MESA), and the Rotterdam Study. Journal of the American Heart Association. 5. PMID 27207996 DOI: 10.1161/Jaha.115.002907  0.3
2016 Araújo LF, Mirza SS, Bos D, Niessen WJ, Barreto SM, van der Lugt A, Vernooij MW, Hofman A, Tiemeier H, Ikram MA. Association of Coffee Consumption with MRI Markers and Cognitive Function: A Population-Based Study. Journal of Alzheimer's Disease : Jad. PMID 27163820 DOI: 10.3233/Jad-160116  0.538
2016 Dhana K, Berghout MA, Peeters A, Ikram MA, Tiemeier H, Hofman A, Nusselder W, Kavousi M, Franco OH. Obesity in older adults and life expectancy with and without cardiovascular disease. International Journal of Obesity (2005). PMID 27163746 DOI: 10.1038/Ijo.2016.94  0.51
2016 Smith JG, Felix JF, Morrison AC, Kalogeropoulos A, Trompet S, Wilk JB, Gidlöf O, Wang X, Morley M, Mendelson M, Joehanes R, Ligthart S, Shan X, Bis JC, Wang YA, ... ... Hofman A, et al. Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure. Plos Genetics. 12: e1006034. PMID 27149122 DOI: 10.1371/Journal.Pgen.1006034  0.31
2016 Amin N, Allebrandt KV, van der Spek A, Müller-Myhsok B, Hek K, Teder-Laving M, Hayward C, Esko T, van Mill JG, Mbarek H, Watson NF, Melville SA, Del Greco FM, Byrne EM, Oole E, ... ... Hofman A, et al. Genetic variants in RBFOX3 are associated with sleep latency. European Journal of Human Genetics : Ejhg. PMID 27142678 DOI: 10.1038/Ejhg.2016.31  0.597
2016 Mirza SS, Wolters FJ, Swanson SA, Koudstaal PJ, Hofman A, Tiemeier H, Ikram MA. 10-year trajectories of depressive symptoms and risk of dementia: a population-based study. The Lancet. Psychiatry. PMID 27138970 DOI: 10.1016/S2215-0366(16)00097-3  0.549
2016 Schmaal L, Hibar DP, Sämann PG, Hall GB, Baune BT, Jahanshad N, Cheung JW, van Erp TG, Bos D, Ikram MA, Vernooij MW, Niessen WJ, Tiemeier H, Hofman A, Wittfeld K, et al. Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group. Molecular Psychiatry. PMID 27137745 DOI: 10.1038/Mp.2016.60  0.468
2016 Liu F, Hamer MA, Deelen J, Lall JS, Jacobs L, van Heemst D, Murray PG, Wollstein A, de Craen AJ, Uh HW, Zeng C, Hofman A, Uitterlinden AG, Houwing-Duistermaat JJ, Pardo LM, et al. The MC1R Gene and Youthful Looks. Current Biology : Cb. PMID 27133870 DOI: 10.1016/J.Cub.2016.03.008  0.339
2016 Miliku K, Vinkhuyzen A, Blanken LM, McGrath JJ, Eyles DW, Burne TH, Hofman A, Tiemeier H, Steegers EA, Gaillard R, Jaddoe VW. Maternal vitamin D concentrations during pregnancy, fetal growth patterns, and risks of adverse birth outcomes. The American Journal of Clinical Nutrition. PMID 27099250 DOI: 10.3945/Ajcn.115.123752  0.506
2016 Joshi AD, Andersson C, Buch S, Stender S, Noordam R, Weng LC, Weeke PE, Auer PL, Boehm B, Chen C, Choi H, Curhan G, Denny JC, De Vivo I, Eicher JD, ... ... Hofman A, et al. Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-wide Association Studies. Gastroenterology. PMID 27094239 DOI: 10.1053/J.Gastro.2016.04.007  0.349
2016 Aarts N, Zuurbier LA, Noordam R, Hofman A, Tiemeier H, Stricker BH, Visser LE. Use of Selective Serotonin Reuptake Inhibitors and Sleep Quality: A Population-Based Study. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. PMID 27092698 DOI: 10.5664/Jcsm.5932  0.529
2016 Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, ... ... Hofman A, et al. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nature Genetics. PMID 27089181 DOI: 10.1038/Ng.3552  0.629
2016 Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese SE, Markunas CA, Richmond RC, Xu CJ, Küpers LK, Oh SS, Hoyo C, Gruzieva O, Söderhäll C, ... ... Hofman A, et al. DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis. American Journal of Human Genetics. PMID 27040690 DOI: 10.1016/J.Ajhg.2016.02.019  0.528
2016 van Leeuwen EM, Sabo A, Bis JC, Huffman JE, Manichaikul A, Smith AV, Feitosa MF, Demissie S, Joshi PK, Duan Q, Marten J, van Klinken JB, Surakka I, Nolte IM, Zhang W, ... ... Hofman A, et al. Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. Journal of Medical Genetics. PMID 27036123 DOI: 10.1136/Jmedgenet-2015-103439  0.461
2016 Koolhaas CM, Dhana K, Golubic R, Schoufour JD, Hofman A, van Rooij FJ, Franco OH. Physical Activity Types and Coronary Heart Disease Risk in Middle-Aged and Elderly Persons: The Rotterdam Study. American Journal of Epidemiology. PMID 27022033 DOI: 10.1093/Aje/Kwv244  0.329
2016 Fan Q, Verhoeven VJ, Wojciechowski R, Barathi VA, Hysi PG, Guggenheim JA, Höhn R, Vitart V, Khawaja AP, Yamashiro K, Hosseini SM, Lehtimäki T, Lu Y, Haller T, Xie J, ... ... Hofman A, et al. Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error. Nature Communications. 7: 11008. PMID 27020472 DOI: 10.1038/Ncomms11008  0.456
2016 Norby FL, Eryd SA, Niemeijer MN, Rose LM, Smith AV, Yin X, Agarwal SK, Arking DE, Chasman DL, Chen LY, Eijgelsheim M, Engström G, Franco OH, Heeringa J, Hindy G, ... Hofman A, et al. Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium. Plos One. 11: e0151932. PMID 26999784 DOI: 10.1371/Journal.Pone.0151932  0.307
2016 Mous SE, Schoemaker NK, Blanken LM, Thijssen S, van der Ende J, Polderman TJ, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H, White T. The Association of Gender, Age, and Intelligence With Neuropsychological Functioning in Young Typically Developing Children: The Generation R Study. Applied Neuropsychology. Child. 1-20. PMID 26986060 DOI: 10.1080/21622965.2015.1067214  0.619
2016 Parmar PG, Taal HR, Timpson NJ, Thiering E, Lehtimäki T, Marinelli M, Lind PA, Howe LD, Verwoert G, Aalto V, Uitterlinden AG, Briollais L, Evans DM, Wright MJ, Newnham JP, ... ... Hofman A, et al. International GWAS Consortium Identifies Novel Loci Associated with Blood Pressure in Children and Adolescents. Circulation. Cardiovascular Genetics. PMID 26969751 DOI: 10.1161/Circgenetics.115.001190  0.431
2016 Adams H, Ikram MA, Vernooij MW, van Dijk AC, Hofman A, Uitterlinden AG, van Duijn CM, Koudstaal PJ, Franco OH, van der Lugt A, Bos D. Heritability and Genome-Wide Association Analyses of Intracranial Carotid Artery Calcification: The Rotterdam Study. Stroke; a Journal of Cerebral Circulation. PMID 26965845 DOI: 10.1161/Strokeaha.115.012248  0.458
2016 Hassing RJ, Verbon A, de Visser H, Hofman A, Stricker BH. Proton pump inhibitors and gastroenteritis. European Journal of Epidemiology. PMID 26960438 DOI: 10.1007/S10654-016-0136-8  0.322
2016 Dehghan A, Bis JC, White CC, Smith AV, Morrison AC, Cupples LA, Trompet S, Chasman DI, Lumley T, Völker U, Buckley BM, Ding J, Jensen MK, Folsom AR, Kritchevsky SB, ... ... Hofman A, et al. Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium. Plos One. 11: e0144997. PMID 26950853 DOI: 10.1371/Journal.Pone.0144997  0.307
2016 Vidakovic AJ, Gishti O, Voortman T, Felix JF, Williams MA, Hofman A, Demmelmair H, Koletzko B, Tiemeier H, Jaddoe VW, Gaillard R. Maternal plasma PUFA concentrations during pregnancy and childhood adiposity: the Generation R Study. The American Journal of Clinical Nutrition. PMID 26912493 DOI: 10.3945/Ajcn.115.112847  0.506
2016 Ricaño-Ponce I, Zhernakova DV, Deelen P, Luo O, Li X, Isaacs A, Karjalainen J, Di Tommaso J, Borek ZA, Zorro MM, Gutierrez-Achury J, Uitterlinden AG, Hofman A, van Meurs J, et al. Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs. Journal of Autoimmunity. PMID 26898941 DOI: 10.1016/J.Jaut.2016.01.002  0.442
2016 Portegies ML, Bos MJ, Koudstaal PJ, Hofman A, Tiemeier HW, Ikram MA. Anxiety and the Risk of Stroke: The Rotterdam Study. Stroke; a Journal of Cerebral Circulation. PMID 26883500 DOI: 10.1161/Strokeaha.115.012361  0.54
2016 Joubert BR, den Dekker HT, Felix JF, Bohlin J, Ligthart S, Beckett E, Tiemeier H, van Meurs JB, Uitterlinden AG, Hofman A, Håberg SE, Reese SE, Peters MJ, Kulle Andreassen B, Steegers EA, et al. Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns. Nature Communications. 7: 10577. PMID 26861414 DOI: 10.1038/Ncomms10577  0.54
2016 Koks N, Ghassabian A, Greaves-Lord K, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Maternal C-Reactive Protein Concentration in Early Pregnancy and Child Autistic Traits in the General Population. Paediatric and Perinatal Epidemiology. 30: 181-9. PMID 26860445 DOI: 10.1111/Ppe.12261  0.605
2016 Dashti HS, Zuurbier LA, de Jonge E, Voortman T, Jacques PF, Lamon-Fava S, Scheer FA, Kiefte-De Jong JC, Hofman A, Ordovás JM, Franco OH, Tiemeier H. Actigraphic sleep fragmentation, efficiency and duration associate with dietary intake in the Rotterdam Study. Journal of Sleep Research. PMID 26857552 DOI: 10.1111/Jsr.12397  0.503
2016 Lu Y, Day FR, Gustafsson S, Buchkovich ML, Na J, Bataille V, Cousminer DL, Dastani Z, Drong AW, Esko T, Evans DM, Falchi M, Feitosa MF, Ferreira T, Hedman ÅK, ... ... Hofman A, et al. New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nature Communications. 7: 10495. PMID 26833246 DOI: 10.1038/Ncomms10495  0.486
2016 Kilpeläinen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, Pers TH, Schick U, Grarup N, Kutalik Z, Trompet S, ... ... Hofman A, et al. Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nature Communications. 7: 10494. PMID 26833098 DOI: 10.1038/Ncomms10494  0.447
2016 Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y, Taliun D, Olden M, Foster M, Yang Q, Chen MH, ... ... Hofman A, et al. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nature Communications. 7: 10023. PMID 26831199 DOI: 10.1038/Ncomms10023  0.434
2016 Akoudad S, Ikram MA, Portegies ML, Adams HH, Bos D, Hofman A, Koudstaal PJ, Uitterlinden AG, van der Lugt A, van Duijn CM, Vernooij MW. Genetic loci for serum lipid fractions and intracerebral hemorrhage. Atherosclerosis. 246: 287-292. PMID 26820804 DOI: 10.1016/J.Atherosclerosis.2016.01.024  0.439
2016 Mirza SS, Portegies ML, Wolters FJ, Hofman A, Koudstaal PJ, Tiemeier H, Ikram MA. Higher Education Is Associated with a Lower Risk of Dementia after a Stroke or TIA. The Rotterdam Study. Neuroepidemiology. 46: 120-127. PMID 26794600 DOI: 10.1159/000443649  0.541
2016 Ars CL, Nijs IM, Marroun HE, Muetzel R, Schmidt M, Steenweg-de Graaff J, van der Lugt A, Jaddoe VW, Hofman A, Steegers EA, Verhulst FC, Tiemeier H, White T. Prenatal folate, homocysteine and vitamin B12 levels and child brain volumes, cognitive development and psychological functioning: the Generation R Study. The British Journal of Nutrition. 1-9. PMID 26794411 DOI: 10.1017/S0007114515002081  0.598
2016 Minikel EV, Vallabh SM, Lek M, Estrada K, Samocha KE, Sathirapongsasuti JF, McLean CY, Tung JY, Yu LP, Gambetti P, Blevins J, Zhang S, Cohen Y, Chen W, Yamada M, ... ... Hofman A, et al. Quantifying prion disease penetrance using large population control cohorts. Science Translational Medicine. 8: 322ra9. PMID 26791950 DOI: 10.1126/Scitranslmed.Aad5169  0.47
2016 Otowa T, Hek K, Lee M, Byrne EM, Mirza SS, Nivard MG, Bigdeli T, Aggen SH, Adkins D, Wolen A, Fanous A, Keller MC, Castelao E, Kutalik Z, der Auwera SV, ... ... Hofman A, et al. Meta-analysis of genome-wide association studies of anxiety disorders. Molecular Psychiatry. PMID 26754954 DOI: 10.1038/Mp.2015.197  0.566
2016 Liao X, Norata GD, Polak JF, Stehouwer CD, Catapano A, Rundek T, Ezhov M, Sander D, Thompson SG, Lorenz MW, Balakhonova T, Safarova M, Grigore L, Empana JP, ... ... Hofman A, et al. Normative values for carotid intima media thickness and its progression: Are they transferrable outside of their cohort of origin? European Journal of Preventive Cardiology. PMID 26746227 DOI: 10.1177/2047487315625543  0.304
2016 Akoudad S, Aarts N, Noordam R, Ikram MA, Tiemeier H, Hofman A, Stricker BH, Vernooij MW, Visser LE. Antidepressant Use Is Associated With an Increased Risk of Developing Microbleeds. Stroke; a Journal of Cerebral Circulation. 47: 251-4. PMID 26658443 DOI: 10.1161/Strokeaha.115.011574  0.564
2016 Lahousse L, Nocker PD, Hofman A, Stricker B, Brusselle G, Verhamme K. LSC Abstract – Potential use of β-blockers to reduce COPD exacerbations European Respiratory Journal. 48: 239. DOI: 10.1183/13993003.Congress-2016.Oa1502  0.316
2016 Jovanova O, Luik AI, Leening MJG, Noordam R, Aarts N, Hofman A, Franco OH, Dehghan A, Tiemeier H. The long-term risk of recognized and unrecognized myocardial infarction for depression in older men Psychological Medicine. 46: 1951-1960. DOI: 10.1017/S0033291716000544  0.556
2016 Lee SJvd, Wolters FJ, Hofman A, Ikram MA, Amin N, Duijn CMv. Evaluation Of The Absolute Genetic Risk Of Alzheimer'S Disease In The Aging Population Alzheimers & Dementia. 12: 578. DOI: 10.1016/J.Jalz.2016.06.1133  0.314
2015 Luik AI, Noteboom J, Zuurbier LA, Whitmore H, Hofman A, Tiemeier H. Sleep apnea severity and depressive symptoms in a population-based study. Sleep Health. 1: 128-132. PMID 29073376 DOI: 10.1016/j.sleh.2015.03.002  0.459
2015 van Leeuwen EM, Huffman JE, Bis JC, Isaacs A, Mulder M, Sabo A, Smith AV, Demissie S, Manichaikul A, Brody JA, Feitosa MF, Duan Q, Schraut KE, Navarro P, van Vliet-Ostaptchouk JV, ... ... Hofman A, et al. Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C. Npj Aging and Mechanisms of Disease. 1: 15011. PMID 28721259 DOI: 10.1038/npjamd.2015.11  0.343
2015 Mileva-Seitz VR, Luijk MP, van Ijzendoorn MH, Bakermans-Kranenburg MJ, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. ASSOCIATION BETWEEN INFANT NIGHTTIME-SLEEP LOCATION AND ATTACHMENT SECURITY: NO EASY VERDICT. Infant Mental Health Journal. PMID 26719041 DOI: 10.1002/Imhj.21547  0.613
2015 Miliku K, Voortman T, Franco OH, McGrath JJ, Eyles DW, Burne TH, Hofman A, Tiemeier H, Jaddoe VW. Vitamin D status during fetal life and childhood kidney outcomes. European Journal of Clinical Nutrition. PMID 26695721 DOI: 10.1038/Ejcn.2015.216  0.507
2015 Noordam R, van den Berg ME, Niemeijer MN, Aarts N, Hofman A, Tiemeier H, Kors JA, Stricker BH, Eijgelsheim M, Visser LE, Rijnbeek PR. Antidepressants and heart-rate variability in older adults: a population-based study. Psychological Medicine. 1-9. PMID 26679009 DOI: 10.1017/S0033291715002779  0.496
2015 Vidakovic AJ, Jaddoe VW, Gishti O, Felix JF, Williams MA, Hofman A, Demmelmair H, Koletzko B, Tiemeier H, Gaillard R. Body mass index, gestational weight gain and fatty acid concentrations during pregnancy: the Generation R Study. European Journal of Epidemiology. 30: 1175-85. PMID 26666541 DOI: 10.1007/S10654-015-0106-6  0.529
2015 Yu B, Pulit SL, Hwang SJ, Brody JA, Amin N, Auer PL, Bis JC, Boerwinkle E, Burke GL, Chakravarti A, Correa A, Dreisbach AW, Franco OH, Ehret GB, Franceschini N, ... Hofman A, et al. Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk. Circulation. Cardiovascular Genetics. PMID 26658788 DOI: 10.1161/Circgenetics.115.001215  0.338
2015 Mutlu U, Ikram MK, Wolters FJ, Hofman A, Klaver CC, Ikram MA. Retinal Microvasculature Is Associated With Long-Term Survival in the General Adult Dutch Population. Hypertension. PMID 26628677 DOI: 10.1161/Hypertensionaha.115.06619  0.338
2015 Felix JF, Bradfield JP, Monnereau C, van der Valk RJ, Stergiakouli E, Chesi A, Gaillard R, Feenstra B, Thiering E, Kreiner-Møller E, Mahajan A, Pitkänen N, Joro R, Cavadino A, Huikari V, ... ... Hofman A, et al. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Human Molecular Genetics. PMID 26604143 DOI: 10.1093/Hmg/Ddv472  0.326
2015 Wolters FJ, de Bruijn RF, Hofman A, Koudstaal PJ, Ikram MA. Cerebral Vasoreactivity, Apolipoprotein E, and the Risk of Dementia: A Population-Based Study. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26586657 DOI: 10.1161/Atvbaha.115.306768  0.303
2015 Maksimovic A, Hanewinckel R, Verlinden VJ, Ligthart S, Hofman A, Franco OH, van Doorn PA, Tiemeier H, Dehghan A, Ikram MA. Gait characteristics in older adults with diabetes and impaired fasting glucose: The Rotterdam Study. Journal of Diabetes and Its Complications. PMID 26585369 DOI: 10.1016/J.Jdiacomp.2015.10.006  0.513
2015 Jensen RA, Sim X, Smith AV, Li X, Jakobsdóttir J, Cheng CY, Brody JA, Cotch MF, McKnight B, Klein R, Wang JJ, Kifley A, Harris TB, Launer LJ, Taylor KD, ... ... Hofman A, et al. Novel Genetic Loci Associated with Retinal Microvascular Diameter. Circulation. Cardiovascular Genetics. PMID 26567291 DOI: 10.1161/Circgenetics.115.001142  0.359
2015 Serdarevic F, van Batenburg-Eddes T, Mous SE, White T, Hofman A, Jaddoe VW, Verhulst FC, Ghassabian A, Tiemeier H. Relation of infant motor development with nonverbal intelligence, language comprehension and neuropsychological functioning in childhood: a population-based study. Developmental Science. PMID 26549804 DOI: 10.1111/Desc.12326  0.611
2015 Noordam R, Aarts N, Leening MJ, Tiemeier H, Franco OH, Hofman A, Stricker BH, Visser LE. Use of antidepressants and the risk of myocardial infarction in middle-aged and older adults: a matched case-control study. European Journal of Clinical Pharmacology. PMID 26546336 DOI: 10.1007/S00228-015-1972-2  0.538
2015 Bis JC, Sitlani C, Irvin R, Avery CL, Smith AV, Sun F, Evans DS, Musani SK, Li X, Trompet S, Krijthe BP, Harris TB, Quibrera PM, Brody JA, Demissie S, ... ... Hofman A, et al. Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. Plos One. 10: e0140496. PMID 26516778 DOI: 10.1371/Journal.Pone.0140496  0.364
2015 Sonneveld MA, de Maat MP, Portegies ML, Kavousi M, Hofman A, Turecek PL, Rottensteiner H, Scheiflinger F, Koudstaal PJ, Ikram MA, Leebeek FW. Low ADAMTS13 activity is associated with an increased risk of ischemic stroke. Blood. PMID 26511134 DOI: 10.1182/Blood-2015-05-643338  0.305
2015 Liu F, Hamer MA, Heilmann S, Herold C, Moebus S, Hofman A, Uitterlinden AG, Nöthen MM, van Duijn CM, Nijsten TE, Kayser M. Prediction of male-pattern baldness from genotypes. European Journal of Human Genetics : Ejhg. PMID 26508577 DOI: 10.1038/Ejhg.2015.220  0.47
2015 Steenweg-de Graaff J, Roza SJ, Walstra AN, El Marroun H, Steegers EA, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H, White T. Associations of maternal folic acid supplementation and folate concentrations during pregnancy with foetal and child head growth: the Generation R Study. European Journal of Nutrition. PMID 26497537 DOI: 10.1007/S00394-015-1058-Z  0.609
2015 van Loon J, Dehghan A, Weihong T, Trompet S, McArdle WL, Asselbergs FF, Chen MH, Lopez LM, Huffman JE, Leebeek FW, Basu S, Stott DJ, Rumley A, Gansevoort RT, Davies G, ... ... Hofman A, et al. Genome-wide association studies identify genetic loci for low von Willebrand factor levels. European Journal of Human Genetics : Ejhg. PMID 26486471 DOI: 10.1038/Ejhg.2015.222  0.334
2015 Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bønnelykke K, Tian C, Takahashi A, Esparza-Gordillo J, Alves AC, Thyssen JP, den Dekker HT, Ferreira MA, ... ... Hofman A, et al. Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nature Genetics. 47: 1449-56. PMID 26482879 DOI: 10.1038/Ng.3424  0.34
2015 Hofer E, Cavalieri M, Bis JC, DeCarli C, Fornage M, Sigurdsson S, Srikanth V, Trompet S, Verhaaren BF, Wolf C, Yang Q, Adams HH, Amouyel P, Beiser A, Buckley BM, ... ... Hofman A, et al. White Matter Lesion Progression: Genome-Wide Search for Genetic Influences. Stroke; a Journal of Cerebral Circulation. PMID 26451028 DOI: 10.1161/Strokeaha.115.009252  0.469
2015 Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, ... ... Hofman A, et al. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. Plos Genetics. 11: e1005378. PMID 26426971 DOI: 10.1371/Journal.Pgen.1005378  0.457
2015 Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, Stolk L, Finucane HK, Sulem P, Bulik-Sullivan B, Esko T, Johnson AD, Elks CE, Franceschini N, He C, ... ... Hofman A, et al. Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nature Genetics. PMID 26414677 DOI: 10.1097/01.Ogx.0000473766.71624.99  0.466
2015 Hofman A, Brusselle GG, Darwish Murad S, van Duijn CM, Franco OH, Goedegebure A, Ikram MA, Klaver CC, Nijsten TE, Peeters RP, Stricker BH, Tiemeier HW, Uitterlinden AG, Vernooij MW. The Rotterdam Study: 2016 objectives and design update. European Journal of Epidemiology. 30: 661-708. PMID 26386597 DOI: 10.1007/s10654-015-0082-x  0.573
2015 Zheng HF, Forgetta V, Hsu YH, Estrada K, Rosello-Diez A, Leo PJ, Dahia CL, Park-Min KH, Tobias JH, Kooperberg C, Kleinman A, Styrkarsdottir U, Liu CT, Uggla C, Evans DS, ... ... Hofman A, et al. Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture. Nature. PMID 26367794 DOI: 10.1038/Nature14878  0.449
2015 Lucassen N, Kok R, Bakermans-Kranenburg MJ, Van IJzendoorn MH, Jaddoe VW, Hofman A, Verhulst FC, Lambregtse-Van den Berg MP, Tiemeier H. Executive functions in early childhood: The role of maternal and paternal parenting practices. The British Journal of Developmental Psychology. PMID 26359942 DOI: 10.1111/Bjdp.12112  0.583
2015 Lahousse L, Ziere G, Verlinden VJ, Zillikens MC, Uitterlinden AG, Rivadeneira F, Tiemeier H, Joos GF, Hofman A, Ikram MA, Franco OH, Brusselle GG, Stricker BH. Risk of Frailty in Elderly With COPD: A Population-Based Study. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 26355016 DOI: 10.1093/Gerona/Glv154  0.542
2015 Nikpay M, Goel A, Won HH, Hall LM, Willenborg C, Kanoni S, Saleheen D, Kyriakou T, Nelson CP, Hopewell JC, Webb TR, Zeng L, Dehghan A, Alver M, Armasu SM, ... ... Hofman A, et al. A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Nature Genetics. 47: 1121-30. PMID 26343387 DOI: 10.1038/Ng.3396  0.327
2015 Mous SE, Hammerschlag AR, Polderman TJ, Verhulst FC, Tiemeier H, van der Lugt A, Jaddoe VW, Hofman A, White T, Posthuma D. A Population-Based Imaging Genetics Study of Inattention/Hyperactivity: Basal Ganglia and Genetic Pathways. Journal of the American Academy of Child and Adolescent Psychiatry. 54: 745-52. PMID 26299296 DOI: 10.1016/J.Jaac.2015.05.018  0.597
2015 Peymani A, Adams HH, Cremers LG, Krestin G, Hofman A, van Duijn CM, Uitterlinden AG, van der Lugt A, Vernooij MW, Ikram MA. Genetic Determinants of Unruptured Intracranial Aneurysms in the General Population. Stroke; a Journal of Cerebral Circulation. PMID 26286545 DOI: 10.1161/Strokeaha.115.010414  0.458
2015 Leermakers ET, Kiefte-de Jong JC, Hofman A, Jaddoe VW, Franco OH. Lutein intake at the age of 1 year and cardiometabolic health at the age of 6 years: the Generation R Study. The British Journal of Nutrition. 1-9. PMID 26286042 DOI: 10.1017/S0007114515002779  0.339
2015 Rucci E, den Dekker HT, de Jongste JC, Steenweg-de Graaff J, Gaillard R, Pasmans SG, Hofman A, Tiemeier H, Jaddoe VW, Duijts L. Maternal fatty acid levels during pregnancy, childhood lung function and atopic diseases. The Generation R Study. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. PMID 26285050 DOI: 10.1111/cea.12613  0.472
2015 Bautista Niño PK, Tielemans MJ, Schalekamp-Timmermans S, Steenweg-de Graaff J, Hofman A, Tiemeier H, Jaddoe VW, Steegers EA, Felix JF, Franco OH. Maternal fish consumption, fatty acid levels and angiogenic factors: The Generation R Study. Placenta. PMID 26278058 DOI: 10.1016/J.Placenta.2015.07.125  0.526
2015 Bouwland-Both MI, van Mil NH, Tolhoek CP, Stolk L, Eilers PH, Verbiest MM, Heijmans BT, Uitterlinden AG, Hofman A, van Ijzendoorn MH, Duijts L, de Jongste JC, Tiemeier H, Steegers EA, Jaddoe VW, et al. Prenatal parental tobacco smoking, gene specific DNA methylation, and newborns size: the Generation R study. Clinical Epigenetics. 7: 83. PMID 26265957 DOI: 10.1186/S13148-015-0115-Z  0.519
2015 Sedaghat S, Vernooij MW, Loehrer E, Mattace-Raso FU, Hofman A, van der Lugt A, Franco OH, Dehghan A, Ikram MA. Kidney Function and Cerebral Blood Flow: The Rotterdam Study. Journal of the American Society of Nephrology : Jasn. PMID 26251352 DOI: 10.1681/Asn.2014111118  0.302
2015 Vidakovic AJ, Gishti O, Steenweg-de Graaff J, Williams MA, Duijts L, Felix JF, Hofman A, Tiemeier H, Jaddoe VW, Gaillard R. Higher Maternal Plasma n-3 PUFA and Lower n-6 PUFA Concentrations in Pregnancy Are Associated with Lower Childhood Systolic Blood Pressure. The Journal of Nutrition. PMID 26246325 DOI: 10.3945/Jn.115.210823  0.521
2015 Lunetta KL, Day FR, Sulem P, Ruth KS, Tung JY, Hinds DA, Esko T, Elks CE, Altmaier E, He C, Huffman JE, Mihailov E, Porcu E, Robino A, Rose LM, ... ... Hofman A, et al. Rare coding variants and X-linked loci associated with age at menarche. Nature Communications. 6: 7756. PMID 26239645 DOI: 10.1038/Ncomms8756  0.33
2015 Medina-Gómez C, Chesi A, Heppe DH, Zemel BS, Yin JL, Kalkwarf HJ, Hofman A, Lappe JM, Kelly A, Kayser M, Oberfield SE, Gilsanz V, Uitterlinden AG, Shepherd JA, Jaddoe VW, et al. BMD Loci Contribute to Ethnic And Developmental Differences in Skeletal Fragility Across Populations: Assessment of Evolutionary Selection Pressures. Molecular Biology and Evolution. PMID 26226985 DOI: 10.1093/Molbev/Msv170  0.315
2015 Plompen EP, Murad SD, Hansen BE, Loth DW, Schouten JN, Taimr P, Hofman A, Uitterlinden AG, Stricker BH, Janssen HL, Leebeek FW. Prothrombotic Genetic Risk Factors are associated with an Increased Risk of Liver Fibrosis in the General Population: The Rotterdam Study. Journal of Hepatology. PMID 26226452 DOI: 10.1016/J.Jhep.2015.07.026  0.32
2015 Verlinden VJ, Maksimovic A, Mirza SS, Ikram MA, Kiefte-de Jong JC, Hofman A, Franco OH, Tiemeier H, van der Geest JN. The associations of alcohol, coffee and tobacco consumption with gait in a community-dwelling population. European Journal of Clinical Nutrition. PMID 26220568 DOI: 10.1038/Ejcn.2015.120  0.522
2015 Adams HH, Verlinden VJ, Callisaya ML, van Duijn CM, Hofman A, Thomson R, Uitterlinden AG, Vernooij MW, van der Geest JN, Srikanth V, Ikram MA. Heritability and Genome-Wide Association Analyses of Human Gait Suggest Contribution of Common Variants. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 26219847 DOI: 10.1093/Gerona/Glv081  0.47
2015 Zuurbier LA, Ikram MA, Luik AI, Hofman A, Van Someren EJ, Vernooij MW, Tiemeier H. Cerebral small vessel disease is related to disturbed 24-h activity rhythms: a population-based study. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. PMID 26206535 DOI: 10.1111/Ene.12775  0.525
2015 de Kruijf M, Peters MJ, C Jacobs L, Tiemeier H, Nijsten T, Hofman A, Uitterlinden AG, Huygen FJ, van Meurs JB. Determinants for Quantitative Sensory Testing and the Association with Chronic Musculoskeletal Pain in the General Elderly Population. Pain Practice : the Official Journal of World Institute of Pain. PMID 26205731 DOI: 10.1111/Papr.12335  0.501
2015 de Bruijn RF, Bos MJ, Portegies ML, Hofman A, Franco OH, Koudstaal PJ, Ikram MA. The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study. Bmc Medicine. 13: 132. PMID 26195085 DOI: 10.1186/S12916-015-0377-5  0.36
2015 Younge JO, Leening MJ, Tiemeier H, Franco OH, Kiefte-de Jong J, Hofman A, Roos-Hesselink JW, Hunink MG. Association Between Mind-Body Practice and Cardiometabolic Risk Factors: The Rotterdam Study. Psychosomatic Medicine. 77: 775-83. PMID 26186434 DOI: 10.1097/Psy.0000000000000213  0.532
2015 Koehler EM, Plompen EP, Schouten JN, Hansen BE, Darwish Murad S, Taimr P, Leebeek FW, Hofman A, Stricker BH, Castera L, Janssen HL. Presence of Diabetes Mellitus and Steatosis is Associated with Liver Stiffness in a General Population: The Rotterdam Study. Hepatology (Baltimore, Md.). PMID 26171685 DOI: 10.1002/Hep.27981  0.322
2015 Dhana K, Kavousi M, Ikram MA, Tiemeier HW, Hofman A, Franco OH. Body shape index in comparison with other anthropometric measures in prediction of total and cause-specific mortality. Journal of Epidemiology and Community Health. PMID 26160362 DOI: 10.1136/Jech-2014-205257  0.514
2015 Modesto T, Tiemeier H, Peeters RP, Jaddoe VW, Hofman A, Verhulst FC, Ghassabian A. Maternal Mild Thyroid Hormone Insufficiency in Early Pregnancy and Attention-Deficit/Hyperactivity Disorder Symptoms in Children. Jama Pediatrics. 169: 838-45. PMID 26146876 DOI: 10.1001/Jamapediatrics.2015.0498  0.592
2015 Akoudad S, Portegies ML, Koudstaal PJ, Hofman A, van der Lugt A, Ikram MA, Vernooij MW. Cerebral Microbleeds Are Associated With an Increased Risk of Stroke: The Rotterdam Study. Circulation. 132: 509-16. PMID 26137955 DOI: 10.1161/Circulationaha.115.016261  0.311
2015 Noordam R, Aarts N, Tiemeier H, Hofman A, Stricker BH, Visser LE. Sex-specific association between antidepressant use and body weight in a population-based study in older adults. The Journal of Clinical Psychiatry. 76: e745-51. PMID 26132681 DOI: 10.4088/Jcp.13M08896  0.524
2015 Schmaal L, Veltman DJ, van Erp TG, Sämann PG, Frodl T, Jahanshad N, Loehrer E, Tiemeier H, Hofman A, Niessen WJ, Vernooij MW, Ikram MA, Wittfeld K, Grabe HJ, Block A, et al. Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group. Molecular Psychiatry. PMID 26122586 DOI: 10.1038/Mp.2015.69  0.483
2015 Verkouteren JA, Smedinga H, Steyerberg EW, Hofman A, Nijsten T. Predicting the Risk of a Second Basal Cell Carcinoma. The Journal of Investigative Dermatology. PMID 26121210 DOI: 10.1038/Jid.2015.244  0.31
2015 Huffman JE, de Vries PS, Morrison AC, Sabater-Lleal M, Kacprowski T, Auer PL, Brody JA, Chasman DI, Chen MH, Guo X, Lin LA, Marioni RE, Müller-Nurasyid M, Yanek LR, Pankratz N, ... ... Hofman A, et al. Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF. Blood. 126: e19-29. PMID 26105150 DOI: 10.1182/Blood-2015-02-624551  0.308
2015 Verlinden M, Jansen PW, Veenstra R, Jaddoe VW, Hofman A, Verhulst FC, Shaw P, Tiemeier H. Preschool Attention-Deficit/Hyperactivity and Oppositional Defiant Problems as Antecedents of School Bullying. Journal of the American Academy of Child and Adolescent Psychiatry. 54: 571-9. PMID 26088662 DOI: 10.1016/J.Jaac.2015.05.002  0.579
2015 van Nistelrooij AM, van der Korput HA, Broer L, van Marion R, van Berge Henegouwen MI, van Noesel CJ, Biermann K, Spaander MC, Tilanus HW, van Lanschot JJ, Hofman A, Uitterlinden AG, Wijnhoven BP, Dinjens WN. Single nucleotide polymorphisms in CRTC1 and BARX1 are associated with esophageal adenocarcinoma. Journal of Carcinogenesis. 14: 5. PMID 26085818 DOI: 10.4103/1477-3163.157441  0.328
2015 Krishnadath IS, Smits CC, Jaddoe VW, Hofman A, Toelsie JR. A National Surveillance Survey on Noncommunicable Disease Risk Factors: Suriname Health Study Protocol. Jmir Research Protocols. 4: e75. PMID 26085372 DOI: 10.2196/Resprot.4205  0.339
2015 Power RA, Steinberg S, Bjornsdottir G, Rietveld CA, Abdellaoui A, Nivard MM, Johannesson M, Galesloot TE, Hottenga JJ, Willemsen G, Cesarini D, Benjamin DJ, Magnusson PK, Ullén F, Tiemeier H, ... Hofman A, et al. Polygenic risk scores for schizophrenia and bipolar disorder predict creativity. Nature Neuroscience. 18: 953-5. PMID 26053403 DOI: 10.1038/Nn.4040  0.516
2015 Cuellar-Partida G, Springelkamp H, Lucas SE, Yazar S, Hewitt AW, Iglesias AI, Montgomery GW, Martin NG, Pennell CE, van Leeuwen EM, Verhoeven VJ, Hofman A, Uitterlinden AG, Ramdas WD, Wolfs RC, et al. WNT10A exonic variant increases the risk of keratoconus by decreasing corneal thickness. Human Molecular Genetics. PMID 26049155 DOI: 10.1093/Hmg/Ddv211  0.489
2015 Luik AI, Zuurbier LA, Hofman A, Van Someren EJ, Ikram MA, Tiemeier H. Associations of the 24-h activity rhythm and sleep with cognition: a population-based study of middle-aged and elderly persons. Sleep Medicine. 16: 850-5. PMID 26028055 DOI: 10.1016/J.Sleep.2015.03.012  0.54
2015 Hägg S, Fall T, Ploner A, Mägi R, Fischer K, Draisma HH, Kals M, de Vries PS, Dehghan A, Willems SM, Sarin AP, Kristiansson K, Nuotio ML, Havulinna AS, de Bruijn RF, ... ... Hofman A, et al. Adiposity as a cause of cardiovascular disease: a Mendelian randomization study. International Journal of Epidemiology. 44: 578-86. PMID 26016847 DOI: 10.1093/Ije/Dyv094  0.46
2015 Nettleton JA, Follis JL, Ngwa JS, Smith CE, Ahmad S, Tanaka T, Wojczynski MK, Voortman T, Lemaitre RN, Kristiansson K, Nuotio ML, Houston DK, Perälä MM, Qi Q, Sonestedt E, ... ... Hofman A, et al. Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry. Human Molecular Genetics. 24: 4728-38. PMID 25994509 DOI: 10.1093/Hmg/Ddv186  0.314
2015 Williams KM, Bertelsen G, Cumberland P, Wolfram C, Verhoeven VJ, Anastasopoulos E, Buitendijk GH, Cougnard-Grégoire A, Creuzot-Garcher C, Erke MG, Hogg R, Höhn R, Hysi P, Khawaja AP, Korobelnik JF, ... ... Hofman A, et al. Increasing Prevalence of Myopia in Europe and the Impact of Education. Ophthalmology. PMID 25983215 DOI: 10.1016/J.Ophtha.2015.03.018  0.466
2015 Maljuric NM, Noordam R, Aarts N, Niemeijer MN, van den Berg ME, Hofman A, Kors JA, Stricker BH, Visser LE. Use of selective serotonin reuptake inhibitors and the heart-rate corrected QT interval in a real-life setting: the population-based Rotterdam Study. British Journal of Clinical Pharmacology. PMID 25966843 DOI: 10.1111/Bcp.12681  0.304
2015 Korevaar TI, Steegers EA, de Rijke YB, Schalekamp-Timmermans S, Visser WE, Hofman A, Jaddoe VW, Tiemeier H, Visser TJ, Medici M, Peeters RP. Reference ranges and determinants of total hCG levels during pregnancy: the Generation R Study. European Journal of Epidemiology. 30: 1057-66. PMID 25963653 DOI: 10.1007/S10654-015-0039-0  0.536
2015 de Vries PS, Boender J, Sonneveld MA, Rivadeneira F, Ikram MA, Rottensteiner H, Hofman A, Uitterlinden AG, Leebeek FW, Franco OH, Dehghan A, de Maat MP. Genetic variants in the ADAMTS13 and SUPT3H genes are associated with ADAMTS13 activity. Blood. 125: 3949-55. PMID 25934476 DOI: 10.1182/Blood-2015-02-629865  0.304
2015 Mirza SS, de Bruijn RF, Koudstaal PJ, van den Meiracker AH, Franco OH, Hofman A, Tiemeier H, Ikram MA. The N-terminal pro B-type natriuretic peptide, and risk of dementia and cognitive decline: a 10-year follow-up study in the general population. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 25918047 DOI: 10.1136/Jnnp-2014-309968  0.542
2015 Adams HH, de Bruijn RF, Hofman A, Uitterlinden AG, van Duijn CM, Vernooij MW, Koudstaal PJ, Ikram MA. Genetic risk of neurodegenerative diseases is associated with mild cognitive impairment and conversion to dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25916564 DOI: 10.1016/J.Jalz.2014.12.008  0.47
2015 Ringoot AP, Tiemeier H, Jaddoe VW, So P, Hofman A, Verhulst FC, Jansen PW. Parental depression and child well-being: young children's self-reports helped addressing biases in parent reports. Journal of Clinical Epidemiology. 68: 928-38. PMID 25900418 DOI: 10.1016/J.Jclinepi.2015.03.009  0.584
2015 Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, Chibnik LB, Liu Y, Vitart V, Kirin M, Petrovic K, ... ... Hofman A, et al. GWAS for executive function and processing speed suggests involvement of the CADM2 gene. Molecular Psychiatry. PMID 25869804 DOI: 10.1038/Mp.2015.37  0.329
2015 Basten M, Tiemeier H, Althoff RR, van de Schoot R, Jaddoe VW, Hofman A, Hudziak JJ, Verhulst FC, van der Ende J. The Stability of Problem Behavior Across the Preschool Years: An Empirical Approach in the General Population. Journal of Abnormal Child Psychology. PMID 25832625 DOI: 10.1007/S10802-015-9993-Y  0.598
2015 van der Lee SJ, Holstege H, Wong TH, Jakobsdottir J, Bis JC, Chouraki V, van Rooij JG, Grove ML, Smith AV, Amin N, Choi SH, Beiser AS, Garcia ME, van IJcken WF, Pijnenburg YA, ... ... Hofman A, et al. PLD3 variants in population studies. Nature. 520: E2-3. PMID 25832410 DOI: 10.1038/Nature14038  0.461
2015 Huffman JE, Albrecht E, Teumer A, Mangino M, Kapur K, Johnson T, Kutalik Z, Pirastu N, Pistis G, Lopez LM, Haller T, Salo P, Goel A, Li M, Tanaka T, ... ... Hofman A, et al. Modulation of genetic associations with serum urate levels by body-mass-index in humans. Plos One. 10: e0119752. PMID 25811787 DOI: 10.1371/Journal.Pone.0119752  0.451
2015 Thijssen S, Ringoot AP, Wildeboer A, Bakermans-Kranenburg MJ, El Marroun H, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H, van IJzendoorn MH, White T. Brain morphology of childhood aggressive behavior: A multi-informant study in school-age children. Cognitive, Affective & Behavioral Neuroscience. PMID 25801924 DOI: 10.3758/S13415-015-0344-9  0.609
2015 Williams KM, Verhoeven VJ, Cumberland P, Bertelsen G, Wolfram C, Buitendijk GH, Hofman A, van Duijn CM, Vingerling JR, Kuijpers RW, Höhn R, Mirshahi A, Khawaja AP, Luben RN, Erke MG, et al. Prevalence of refractive error in Europe: the European Eye Epidemiology (E(3)) Consortium. European Journal of Epidemiology. 30: 305-15. PMID 25784363 DOI: 10.1007/S10654-015-0010-0  0.444
2015 Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, ... ... Hofman A, et al. A novel Alzheimer disease locus located near the gene encoding tau protein. Molecular Psychiatry. PMID 25778476 DOI: 10.1038/Mp.2015.23  0.338
2015 Ligthart S, de Vries PS, Uitterlinden AG, Hofman A, Franco OH, Chasman DI, Dehghan A. Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein. Plos One. 10: e0118859. PMID 25768928 DOI: 10.1371/Journal.Pone.0118859  0.322
2015 Medina-Gomez C, Felix JF, Estrada K, Peters MJ, Herrera L, Kruithof CJ, Duijts L, Hofman A, van Duijn CM, Uitterlinden AG, Jaddoe VW, Rivadeneira F. Challenges in conducting genome-wide association studies in highly admixed multi-ethnic populations: the Generation R Study. European Journal of Epidemiology. 30: 317-30. PMID 25762173 DOI: 10.1007/S10654-015-9998-4  0.465
2015 Gishti O, Jaddoe VW, Felix JF, Klaver CC, Hofman A, Wong TY, Ikram MK, Gaillard R. Retinal microvasculature and cardiovascular health in childhood. Pediatrics. 135: 678-85. PMID 25755243 DOI: 10.1542/Peds.2014-3341  0.3
2015 van Leeuwen EM, Karssen LC, Deelen J, Isaacs A, Medina-Gomez C, Mbarek H, Kanterakis A, Trompet S, Postmus I, Verweij N, van Enckevort DJ, Huffman JE, White CC, Feitosa MF, Bartz TM, ... ... Hofman A, et al. Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels. Nature Communications. 6: 6065. PMID 25751400 DOI: 10.1038/Ncomms7065  0.455
2015 Hanewinckel R, Maksimovic A, Verlinden VJ, van der Geest JN, Hofman A, van Doorn PA, Boon AJ, Tiemeier H, Ikram MA. The impact of restless legs syndrome on physical functioning in a community-dwelling population of middle-aged and elderly people. Sleep Medicine. 16: 399-405. PMID 25747142 DOI: 10.1016/J.Sleep.2014.11.013  0.524
2015 Reinthaler EM, Dejanovic B, Lal D, Semtner M, Merkler Y, Reinhold A, Pittrich DA, Hotzy C, Feucht M, Steinböck H, Gruber-Sedlmayr U, Ronen GM, Neophytou B, Geldner J, Haberlandt E, ... ... Hofman A, et al. Rare variants in γ-aminobutyric acid type A receptor genes in rolandic epilepsy and related syndromes. Annals of Neurology. 77: 972-86. PMID 25726841 DOI: 10.1002/Ana.24395  0.392
2015 Jacobs LC, Liu F, Pardo LM, Hofman A, Uitterlinden AG, Kayser M, Nijsten T. IRF4, MC1R and TYR genes are risk factors for actinic keratosis independent of skin color. Human Molecular Genetics. 24: 3296-303. PMID 25724930 DOI: 10.1093/Hmg/Ddv076  0.327
2015 Luijk MP, Linting M, Henrichs J, Herba CM, Verhage ML, Schenk JJ, Arends LR, Raat H, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H, van IJzendoorn MH. Hours in non-parental child care are related to language development in a longitudinal cohort study. Child: Care, Health and Development. PMID 25722078 DOI: 10.1111/Cch.12238  0.571
2015 Rijlaarsdam J, Stevens GW, van der Ende J, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Prevalence of DSM-IV disorders in a population-based sample of 5- to 8-year-old children: the impact of impairment criteria. European Child & Adolescent Psychiatry. PMID 25715995 DOI: 10.1007/S00787-015-0684-6  0.608
2015 Fall T, Hägg S, Ploner A, Mägi R, Fischer K, Draisma HH, Sarin AP, Benyamin B, Ladenvall C, Åkerlund M, Kals M, Esko T, Nelson CP, Kaakinen M, Huikari V, ... ... Hofman A, et al. Age- and sex-specific causal effects of adiposity on cardiovascular risk factors. Diabetes. 64: 1841-52. PMID 25712996 DOI: 10.2337/Db14-0988  0.484
2015 Jacobs LC, Hamer MA, Gunn DA, Deelen J, Lall JS, van Heemst D, Uh HW, Hofman A, Uitterlinden AG, Griffiths CE, Beekman M, Slagboom PE, Kayser M, Liu F, Nijsten T. A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots. The Journal of Investigative Dermatology. 135: 1735-42. PMID 25705849 DOI: 10.1038/Jid.2015.62  0.321
2015 Sajjad A, Tharner A, Kiefte-de Jong JC, Jaddoe VV, Hofman A, Verhulst FC, Franco OH, Tiemeier H, Roza SJ. Breastfeeding duration and non-verbal IQ in children. Journal of Epidemiology and Community Health. 69: 775-81. PMID 25700532 DOI: 10.1136/Jech-2014-204486  0.596
2015 Thijssen S, Wildeboer A, Muetzel RL, Bakermans-Kranenburg MJ, El Marroun H, Hofman A, Jaddoe VW, van der Lugt A, Verhulst FC, Tiemeier H, van IJzendoorn MH, White T. Cortical thickness and prosocial behavior in school-age children: A population-based MRI study. Social Neuroscience. 1-12. PMID 25695908 DOI: 10.1080/17470919.2015.1014063  0.594
2015 Luik AI, Zuurbier LA, Direk N, Hofman A, Van Someren EJ, Tiemeier H. 24-HOUR ACTIVITY RHYTHM AND SLEEP DISTURBANCES IN DEPRESSION AND ANXIETY: A POPULATION-BASED STUDY OF MIDDLE-AGED AND OLDER PERSONS. Depression and Anxiety. PMID 25693731 DOI: 10.1002/Da.22355  0.525
2015 Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, ... ... Hofman A, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 518: 197-206. PMID 25673413 DOI: 10.1038/Nature14177  0.521
2015 Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, ... ... Hofman A, et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 518: 187-96. PMID 25673412 DOI: 10.1038/Nature14132  0.443
2015 Chauhan G, Adams HH, Bis JC, Weinstein G, Yu L, Töglhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, ... ... Hofman A, et al. Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. Neurobiology of Aging. 36: 1765.e7-16. PMID 25670335 DOI: 10.1016/J.Neurobiolaging.2014.12.028  0.508
2015 Gishti O, Gaillard R, Durmus B, Abrahamse M, van der Beek EM, Hofman A, Franco OH, de Jonge LL, Jaddoe VW. BMI, total and abdominal fat distribution, and cardiovascular risk factors in school-age children. Pediatric Research. 77: 710-8. PMID 25665058 DOI: 10.1038/Pr.2015.29  0.308
2015 Verhaaren BF, Debette S, Bis JC, Smith JA, Ikram MK, Adams HH, Beecham AH, Rajan KB, Lopez LM, Barral S, van Buchem MA, van der Grond J, Smith AV, Hegenscheid K, Aggarwal NT, ... ... Hofman A, et al. Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI. Circulation. Cardiovascular Genetics. 8: 398-409. PMID 25663218 DOI: 10.1161/Circgenetics.114.000858  0.488
2015 Freak-Poli R, Mirza SS, Franco OH, Ikram MA, Hofman A, Tiemeier H. Positive affect is not associated with incidence of cardiovascular disease: a population-based study of older persons. Preventive Medicine. 74: 14-20. PMID 25661731 DOI: 10.1016/J.Ypmed.2015.01.032  0.542
2015 Saeed Mirza S, Ikram MA, Hofman A, Tiemeier H. Anxiety does not predict mortality. A population-based study. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 14: 103-4. PMID 25655167 DOI: 10.1002/Wps.20192  0.537
2015 Noordam R, Direk N, Sitlani CM, Aarts N, Tiemeier H, Hofman A, Uitterlinden AG, Psaty BM, Stricker BH, Visser LE. Identifying genetic loci associated with antidepressant drug response with drug-gene interaction models in a population-based study. Journal of Psychiatric Research. 62: 31-7. PMID 25649181 DOI: 10.1016/J.Jpsychires.2015.01.005  0.56
2015 Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, Davies G, Wolf C, Gudnason V, Chibnik LB, Yang Q, deStefano AL, de Quervain DJ, Srikanth V, Lahti J, ... ... Hofman A, et al. Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biological Psychiatry. 77: 749-63. PMID 25648963 DOI: 10.1016/J.Biopsych.2014.08.027  0.633
2015 Davies G, Armstrong N, Bis JC, Bressler J, Chouraki V, Giddaluru S, Hofer E, Ibrahim-Verbaas CA, Kirin M, Lahti J, van der Lee SJ, Le Hellard S, Liu T, Marioni RE, Oldmeadow C, ... ... Hofman A, et al. Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949). Molecular Psychiatry. 20: 183-92. PMID 25644384 DOI: 10.1038/Mp.2014.188  0.341
2015 Cardona Cano S, Tiemeier H, Van Hoeken D, Tharner A, Jaddoe VW, Hofman A, Verhulst FC, Hoek HW. Trajectories of picky eating during childhood: A general population study. The International Journal of Eating Disorders. PMID 25644130 DOI: 10.1002/Eat.22384  0.598
2015 Springelkamp H, Iglesias AI, Cuellar-Partida G, Amin N, Burdon KP, van Leeuwen EM, Gharahkhani P, Mishra A, van der Lee SJ, Hewitt AW, Rivadeneira F, Viswanathan AC, Wolfs RC, Martin NG, Ramdas WD, ... ... Hofman A, et al. ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure. Human Molecular Genetics. 24: 2689-99. PMID 25637523 DOI: 10.1093/Hmg/Ddv027  0.489
2015 Luik AI, Direk N, Zuurbier LA, Hofman A, Van Someren EJ, Tiemeier H. Sleep and 24-h activity rhythms in relation to cortisol change after a very low-dose of dexamethasone. Psychoneuroendocrinology. 53: 207-16. PMID 25635613 DOI: 10.1016/J.Psyneuen.2015.01.011  0.503
2015 Springelkamp H, Mishra A, Hysi PG, Gharahkhani P, Höhn R, Khor CC, Cooke Bailey JN, Luo X, Ramdas WD, Vithana E, Koh V, Yazar S, Xu L, Forward H, Kearns LS, ... ... Hofman A, et al. Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology. Genetic Epidemiology. 39: 207-16. PMID 25631615 DOI: 10.1002/Gepi.21886  0.434
2015 Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert MF, Raghavan S, Lipovich L, Hidalgo B, Fox K, Huffman JE, An P, Lu Y, ... ... Hofman A, et al. Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nature Communications. 6: 5897. PMID 25631608 DOI: 10.1038/Ncomms6897  0.433
2015 de Goede B, Timmermans L, van Kempen BJ, van Rooij FJ, Kazemier G, Lange JF, Hofman A, Jeekel J. Risk factors for inguinal hernia in middle-aged and elderly men: results from the Rotterdam Study. Surgery. 157: 540-6. PMID 25596770 DOI: 10.1016/J.Surg.2014.09.029  0.316
2015 Blanken LM, Mous SE, Ghassabian A, Muetzel RL, Schoemaker NK, El Marroun H, van der Lugt A, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H, White T. Cortical morphology in 6- to 10-year old children with autistic traits: a population-based neuroimaging study. The American Journal of Psychiatry. 172: 479-86. PMID 25585034 DOI: 10.1176/Appi.Ajp.2014.14040482  0.606
2015 Luik AI, Zuurbier LA, Whitmore H, Hofman A, Tiemeier H. REM sleep and depressive symptoms in a population-based study of middle-aged and elderly persons. Journal of Sleep Research. 24: 305-8. PMID 25581509 DOI: 10.1111/Jsr.12273  0.511
2015 Ringoot AP, van der Ende J, Jansen PW, Measelle JR, Basten M, So P, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Why Mothers and Young Children Agree or Disagree in Their Reports of the Child's Problem Behavior. Child Psychiatry and Human Development. PMID 25577034 DOI: 10.1007/S10578-014-0531-X  0.593
2015 Steenweg-de Graaff JC, Tiemeier H, Basten MG, Rijlaarsdam J, Demmelmair H, Koletzko B, Hofman A, Jaddoe VW, Verhulst FC, Roza SJ. Maternal LC-PUFA status during pregnancy and child problem behavior: the Generation R Study. Pediatric Research. 77: 489-97. PMID 25521921 DOI: 10.1038/Pr.2014.204  0.595
2015 Spaan S, Pronk A, Koch HM, Jusko TA, Jaddoe VW, Shaw PA, Tiemeier HM, Hofman A, Pierik FH, Longnecker MP. Reliability of concentrations of organophosphate pesticide metabolites in serial urine specimens from pregnancy in the Generation R Study. Journal of Exposure Science & Environmental Epidemiology. 25: 286-94. PMID 25515376 DOI: 10.1038/Jes.2014.81  0.518
2015 Luijk MP, Sonnenschein-van der Voort AM, Mileva-Seitz VR, Jansen PW, Verhulst FC, Hofman A, Jaddoe VW, de Jongste JC, van IJzendoorn MH, Duijts L, Tiemeier H. Is parent-child bed-sharing a risk for wheezing and asthma in early childhood? The European Respiratory Journal. 45: 661-9. PMID 25504998 DOI: 10.1183/09031936.00041714  0.604
2015 Sajjad A, Mirza SS, Portegies ML, Bos MJ, Hofman A, Koudstaal PJ, Tiemeier H, Ikram MA. Subjective memory complaints and the risk of stroke. Stroke; a Journal of Cerebral Circulation. 46: 170-5. PMID 25503545 DOI: 10.1161/Strokeaha.114.006616  0.542
2015 Gorski M, Tin A, Garnaas M, McMahon GM, Chu AY, Tayo BO, Pattaro C, Teumer A, Chasman DI, Chalmers J, Hamet P, Tremblay J, Woodward M, Aspelund T, Eiriksdottir G, ... ... Hofman A, et al. Genome-wide association study of kidney function decline in individuals of European descent. Kidney International. 87: 1017-29. PMID 25493955 DOI: 10.1038/Ki.2014.361  0.306
2015 Zuurbier LA, Luik AI, Hofman A, Franco OH, Van Someren EJ, Tiemeier H. Fragmentation and stability of circadian activity rhythms predict mortality: the Rotterdam study. American Journal of Epidemiology. 181: 54-63. PMID 25491893 DOI: 10.1093/Aje/Kwu245  0.514
2015 Mileva-Seitz VR, Ghassabian A, Bakermans-Kranenburg MJ, van den Brink JD, Linting M, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H, van IJzendoorn MH. Are boys more sensitive to sensitivity? Parenting and executive function in preschoolers. Journal of Experimental Child Psychology. 130: 193-208. PMID 25462041 DOI: 10.1016/J.Jecp.2014.08.008  0.604
2015 de Barse LM, Tharner A, Micali N, Jaddoe VV, Hofman A, Verhulst FC, Franco OH, Tiemeier H, Jansen PW. Does maternal history of eating disorders predict mothers' feeding practices and preschoolers' emotional eating? Appetite. 85: 1-7. PMID 25450896 DOI: 10.1016/J.Appet.2014.10.031  0.604
2015 Tharner A, Jansen PW, Kiefte-de Jong JC, Moll HA, Hofman A, Jaddoe VW, Tiemeier H, Franco OH. Bidirectional associations between fussy eating and functional constipation in preschool children. The Journal of Pediatrics. 166: 91-6. PMID 25443999 DOI: 10.1016/J.Jpeds.2014.09.028  0.53
2015 Zuurbier LA, Luik AI, Leening MJ, Hofman A, Freak-Poli R, Franco OH, Stricker BH, Tiemeier H. Associations of heart failure with sleep quality: the Rotterdam Study. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 11: 117-21. PMID 25406270 DOI: 10.5664/Jcsm.4454  0.497
2015 Li Q, Wojciechowski R, Simpson CL, Hysi PG, Verhoeven VJ, Ikram MK, Höhn R, Vitart V, Hewitt AW, Oexle K, Mäkelä KM, MacGregor S, Pirastu M, Fan Q, Cheng CY, ... ... Hofman A, et al. Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium. Human Genetics. 134: 131-46. PMID 25367360 DOI: 10.1007/S00439-014-1500-Y  0.493
2015 Saavedra Pérez HC, Ikram MA, Direk N, Prigerson HG, Freak-Poli R, Verhaaren BF, Hofman A, Vernooij M, Tiemeier H. Cognition, structural brain changes and complicated grief. A population-based study. Psychological Medicine. 45: 1389-99. PMID 25363662 DOI: 10.1017/S0033291714002499  0.549
2015 Plompen EP, Hansen BE, Schouten JN, Darwish Murad S, Loth DW, Brouwer WP, Isaacs A, Taimr P, Hofman A, van Duijn CM, Uitterlinden AG, Stricker BH, Leebeek FW, Janssen HL. Interferon gamma receptor 2 gene variants are associated with liver fibrosis in the general population: the Rotterdam Study. Gut. 64: 692-4. PMID 25301852 DOI: 10.1136/Gutjnl-2014-308398  0.421
2015 Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N, Fischer K, Renstrom F, Ngwa JS, Huikari V, Cavadino A, Nolte IM, ... ... Hofman A, et al. Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry. 20: 647-56. PMID 25288136 DOI: 10.1038/Mp.2014.107  0.636
2015 van der Valk RJ, Kreiner-Møller E, Kooijman MN, Guxens M, Stergiakouli E, Sääf A, Bradfield JP, Geller F, Hayes MG, Cousminer DL, Körner A, Thiering E, Curtin JA, Myhre R, Huikari V, ... ... Hofman A, et al. A novel common variant in DCST2 is associated with length in early life and height in adulthood. Human Molecular Genetics. 24: 1155-68. PMID 25281659 DOI: 10.1093/Hmg/Ddu510  0.468
2015 Windhorst DA, Mileva-Seitz VR, Linting M, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H, van IJzendoorn MH, Bakermans-Kranenburg MJ. Differential susceptibility in a developmental perspective: DRD4 and maternal sensitivity predicting externalizing behavior. Developmental Psychobiology. 57: 35-49. PMID 25251423 DOI: 10.1002/Dev.21257  0.613
2015 Vojinovic D, Adams HH, van der Lee SJ, Ibrahim-Verbaas CA, Brouwer R, van den Hout MC, Oole E, van Rooij J, Uitterlinden A, Hofman A, van IJcken WF, Aartsma-Rus A, van Ommen GB, Ikram MA, van Duijn CM, et al. The dystrophin gene and cognitive function in the general population. European Journal of Human Genetics : Ejhg. 23: 837-43. PMID 25227141 DOI: 10.1038/Ejhg.2014.183  0.486
2015 Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, ... ... Hofman A, et al. GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 70: 110-8. PMID 25199915 DOI: 10.1093/Gerona/Glu166  0.608
2015 Verwoert GC, Hofland J, Amin N, Mattace-Raso FU, Sijbrands EJ, Hofman A, van den Meiracker AH, Uitterlinden AG, van Duijn CM, de Jong FH, Danser AH. Expression and gene variation studies deny association of human HSD3B1 gene with aldosterone production or blood pressure. American Journal of Hypertension. 28: 113-20. PMID 24951726 DOI: 10.1093/Ajh/Hpu103  0.419
2015 Versmissen J, Oosterveer DM, Yazdanpanah M, Dehghan A, Hólm H, Erdman J, Aulchenko YS, Thorleifsson G, Schunkert H, Huijgen R, Vongpromek R, Uitterlinden AG, Defesche JC, van Duijn CM, Mulder M, ... ... Hofman A, et al. Identifying genetic risk variants for coronary heart disease in familial hypercholesterolemia: an extreme genetics approach. European Journal of Human Genetics : Ejhg. 23: 381-7. PMID 24916650 DOI: 10.1038/Ejhg.2014.101  0.492
2015 Hoeven TA, Leening MJ, Bindels PJ, Castaño-Betancourt M, van Meurs JB, Franco OH, Kavousi M, Hofman A, Ikram MA, Witteman JC, Bierma-Zeinstra SM. Disability and not osteoarthritis predicts cardiovascular disease: a prospective population-based cohort study. Annals of the Rheumatic Diseases. 74: 752-6. PMID 24385204 DOI: 10.1136/Annrheumdis-2013-204388  0.336
2015 Lahousse L, Niemeijer M, Berg MVd, Rijnbeek P, Joos G, Hofman A, Franco O, Deckers J, Eijgelsheim M, Stricker B, Brusselle G. Chronic obstructive pulmonary disease and sudden cardiac death: The Rotterdam study European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Pa621  0.36
2015 Terzikhan N, Verhamme KMC, Hofman A, Stricker BH, Brusselle GG, Lahousse L. Prevalence and incidence of COPD: The Rotterdam study European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Pa1124  0.327
2015 Wildeboer A, Thijssen S, Van IJzendoorn MH, Van Der Ende J, Jaddoe VWV, Verhulst FC, Hofman A, White T, Tiemeier H, Bakermans-Kranenburg MJ. Early childhood aggression trajectories: Associations with teacher-reported problem behaviour International Journal of Behavioral Development. 39: 221-234. DOI: 10.1177/0165025414562239  0.619
2015 Zwirs BWC, Székely E, Herba CM, Verhulst FC, Jaddoe VWV, Hofman A, van IJzendoorn MH, Tiemeier H. Social and non-social fear in preschoolers and prospective associations with lying about cheating International Journal of Behavioral Development. 39: 477-484. DOI: 10.1177/0165025414553136  0.566
2015 Luik AI, Noteboom J, Zuurbier LA, Whitmore H, Hofman A, Tiemeier H. Sleep apnea severity and depressive symptoms in a population-based study Sleep Health. 1: 128-132. DOI: 10.1016/J.Sleh.2015.03.002  0.54
2015 Portegies MLP, Mirza SS, Hofman A, Tiemeier H, Ikram MA. Does cognitive reserve protect against dementia after a stroke or tia? the rotterdam study Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.189  0.518
2015 Mirza SS, Wolters FJ, Hofman A, Tiemeier H, Ikram MA. Risk of dementia varies with the course of depression over time: The rotterdam study Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.06.215  0.542
2014 Sanchez-Juan P, Bishop MT, Kovacs GG, Calero M, Aulchenko YS, Ladogana A, Boyd A, Lewis V, Ponto C, Calero O, Poleggi A, Carracedo Á, van der Lee SJ, Ströbel T, Rivadeneira F, ... Hofman A, et al. A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk. Plos One. 10: e0123654. PMID 25918841 DOI: 10.1371/Journal.Pone.0123654  0.467
2014 Baumert J, Huang J, McKnight B, Sabater-Lleal M, Steri M, Chu AY, Trompet S, Lopez LM, Fornage M, Teumer A, Tang W, Rudnicka AR, Mälarstig A, Hottenga JJ, Kavousi M, ... ... Hofman A, et al. No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects. Plos One. 9: e111156. PMID 25551457 DOI: 10.1371/Journal.Pone.0111156  0.315
2014 Kruithof CJ, Kooijman MN, van Duijn CM, Franco OH, de Jongste JC, Klaver CC, Mackenbach JP, Moll HA, Raat H, Rings EH, Rivadeneira F, Steegers EA, Tiemeier H, Uitterlinden AG, Verhulst FC, ... ... Hofman A, et al. The Generation R Study: Biobank update 2015. European Journal of Epidemiology. 29: 911-27. PMID 25527369 DOI: 10.1007/S10654-014-9980-6  0.653
2014 Gottlieb DJ, Hek K, Chen TH, Watson NF, Eiriksdottir G, Byrne EM, Cornelis M, Warby SC, Bandinelli S, Cherkas L, Evans DS, Grabe HJ, Lahti J, Li M, Lehtimäki T, ... ... Hofman A, et al. Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study. Molecular Psychiatry. PMID 25469926 DOI: 10.1038/Mp.2014.133  0.303
2014 O'Doherty MG, Jørgensen T, Borglykke A, Brenner H, Schöttker B, Wilsgaard T, Siganos G, Kavousi M, Hughes M, Müezzinler A, Holleczek B, Franco OH, Hofman A, Boffetta P, Trichopoulou A, et al. Repeated measures of body mass index and C-reactive protein in relation to all-cause mortality and cardiovascular disease: results from the consortium on health and ageing network of cohorts in Europe and the United States (CHANCES). European Journal of Epidemiology. 29: 887-97. PMID 25421782 DOI: 10.1007/S10654-014-9954-8  0.328
2014 Leening MJ, Ferket BS, Steyerberg EW, Kavousi M, Deckers JW, Nieboer D, Heeringa J, Portegies ML, Hofman A, Ikram MA, Hunink MG, Franco OH, Stricker BH, Witteman JC, Roos-Hesselink JW. Sex differences in lifetime risk and first manifestation of cardiovascular disease: prospective population based cohort study. Bmj (Clinical Research Ed.). 349: g5992. PMID 25403476 DOI: 10.1136/Bmj.G5992  0.312
2014 van Mil NH, Bouwland-Both MI, Stolk L, Verbiest MM, Hofman A, Jaddoe VW, Verhulst FC, Eilers PH, Uitterlinden AG, Steegers EA, Tiemeier H, Steegers-Theunissen RP. Determinants of maternal pregnancy one-carbon metabolism and newborn human DNA methylation profiles. Reproduction (Cambridge, England). 148: 581-92. PMID 25392189 DOI: 10.1530/Rep-14-0260  0.604
2014 Jansen PW, Tharner A, van der Ende J, Wake M, Raat H, Hofman A, Verhulst FC, van Ijzendoorn MH, Jaddoe VW, Tiemeier H. Feeding practices and child weight: is the association bidirectional in preschool children? The American Journal of Clinical Nutrition. 100: 1329-36. PMID 25332330 DOI: 10.3945/Ajcn.114.088922  0.585
2014 van Leeuwen EM, Smouter FA, Kam-Thong T, Karbalai N, Smith AV, Harris TB, Launer LJ, Sitlani CM, Li G, Brody JA, Bis JC, White CC, Jaiswal A, Oostra BA, Hofman A, et al. The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels. Plos One. 9: e109290. PMID 25329471 DOI: 10.1371/Journal.Pone.0109290  0.467
2014 Leusink M, de Keyser CE, Onland-Moret NC, Hofman A, Visser LE, Stricker BH, de Bakker PI, de Boer A, van Schaik RH, Maitland-van der Zee AH. No association between CYP3A4*22 and statin effectiveness in reducing the risk for myocardial infarction. Pharmacogenomics. 15: 1471-7. PMID 25303298 DOI: 10.2217/Pgs.14.90  0.345
2014 Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J, Kutalik Z, Amin N, Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y, ... ... Hofman A, et al. Defining the role of common variation in the genomic and biological architecture of adult human height. Nature Genetics. 46: 1173-86. PMID 25282103 DOI: 10.1038/Ng.3097  0.444
2014 Pappa I, Mileva-Seitz VR, Szekely E, Verhulst FC, Bakermans-Kranenburg MJ, Jaddoe VW, Hofman A, Tiemeier H, van IJzendoorn MH. DRD4 VNTRs, observed stranger fear in preschoolers and later ADHD symptoms. Psychiatry Research. 220: 982-6. PMID 25262643 DOI: 10.1016/J.Psychres.2014.09.004  0.775
2014 El Marroun H, White TJ, van der Knaap NJ, Homberg JR, Fernández G, Schoemaker NK, Jaddoe VW, Hofman A, Verhulst FC, Hudziak JJ, Stricker BH, Tiemeier H. Prenatal exposure to selective serotonin reuptake inhibitors and social responsiveness symptoms of autism: population-based study of young children. The British Journal of Psychiatry : the Journal of Mental Science. 205: 95-102. PMID 25252317 DOI: 10.1192/Bjp.Bp.113.127746  0.595
2014 Springelkamp H, Höhn R, Mishra A, Hysi PG, Khor CC, Loomis SJ, Bailey JN, Gibson J, Thorleifsson G, Janssen SF, Luo X, Ramdas WD, Vithana E, Nongpiur ME, Montgomery GW, ... ... Hofman A, et al. Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process. Nature Communications. 5: 4883. PMID 25241763 DOI: 10.1038/ncomms5883  0.396
2014 Simpson CL, Wojciechowski R, Oexle K, Murgia F, Portas L, Li X, Verhoeven VJ, Vitart V, Schache M, Hosseini SM, Hysi PG, Raffel LJ, Cotch MF, Chew E, Klein BE, ... ... Hofman A, et al. Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci. Plos One. 9: e107110. PMID 25233373 DOI: 10.1371/Journal.Pone.0107110  0.452
2014 Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, Albrecht E, Ang WQ, Corre T, Cousminer DL, Feenstra B, ... ... Hofman A, et al. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature. 514: 92-7. PMID 25231870 DOI: 10.1038/Nature13545  0.49
2014 St Pourcain B, Cents RA, Whitehouse AJ, Haworth CM, Davis OS, O'Reilly PF, Roulstone S, Wren Y, Ang QW, Velders FP, Evans DM, Kemp JP, Warrington NM, Miller L, Timpson NJ, ... ... Hofman A, et al. Common variation near ROBO2 is associated with expressive vocabulary in infancy. Nature Communications. 5: 4831. PMID 25226531 DOI: 10.1038/Ncomms5831  0.618
2014 Saridjan NS, Velders FP, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. The longitudinal association of the diurnal cortisol rhythm with internalizing and externalizing problems in pre-schoolers. The Generation R Study. Psychoneuroendocrinology. 50: 118-29. PMID 25202831 DOI: 10.1016/J.Psyneuen.2014.08.008  0.605
2014 Sedaghat S, Pazoki R, Uitterlinden AG, Hofman A, Stricker BH, Ikram MA, Franco OH, Dehghan A. Association of uric acid genetic risk score with blood pressure: the Rotterdam study. Hypertension. 64: 1061-6. PMID 25185132 DOI: 10.1161/Hypertensionaha.114.03757  0.336
2014 Chaker L, Baumgartner C, Ikram MA, Dehghan A, Medici M, Visser WE, Hofman A, Rodondi N, Peeters RP, Franco OH. Subclinical thyroid dysfunction and the risk of stroke: a systematic review and meta-analysis. European Journal of Epidemiology. 29: 791-800. PMID 25179793 DOI: 10.1007/S10654-014-9946-8  0.319
2014 Hysi PG, Cheng CY, Springelkamp H, Macgregor S, Bailey JN, Wojciechowski R, Vitart V, Nag A, Hewitt AW, Höhn R, Venturini C, Mirshahi A, Ramdas WD, Thorleifsson G, Vithana E, ... ... Hofman A, et al. Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. Nature Genetics. 46: 1126-30. PMID 25173106 DOI: 10.1038/Ng.3087  0.47
2014 Medici M, Korevaar TI, Schalekamp-Timmermans S, Gaillard R, de Rijke YB, Visser WE, Visser W, de Muinck Keizer-Schrama SM, Hofman A, Hooijkaas H, Bongers-Schokking JJ, Tiemeier H, Jaddoe VW, Visser TJ, Peeters RP, et al. Maternal early-pregnancy thyroid function is associated with subsequent hypertensive disorders of pregnancy: the generation R study. The Journal of Clinical Endocrinology and Metabolism. 99: E2591-8. PMID 25157540 DOI: 10.1210/Jc.2014-1505  0.529
2014 Jansen PW, Verlinden M, Dommisse-van Berkel A, Mieloo CL, Raat H, Hofman A, Jaddoe VW, Verhulst FC, Jansen W, Tiemeier H. Teacher and peer reports of overweight and bullying among young primary school children. Pediatrics. 134: 473-80. PMID 25157018 DOI: 10.1542/Peds.2013-3274  0.606
2014 Mirza SS, Tiemeier H, de Bruijn RF, Hofman A, Franco OH, Kiefte-de Jong J, Koudstaal PJ, Ikram MA. Coffee consumption and incident dementia. European Journal of Epidemiology. 29: 735-41. PMID 25154552 DOI: 10.1007/S10654-014-9943-Y  0.562
2014 Buitendijk GH, Amin N, Hofman A, van Duijn CM, Vingerling JR, Klaver CC. Direct-to-consumer personal genome testing for age-related macular degeneration. Investigative Ophthalmology & Visual Science. 55: 6167-74. PMID 25146986 DOI: 10.1167/Iovs.14-15142  0.426
2014 Mackenbach JD, Ringoot AP, van der Ende J, Verhulst FC, Jaddoe VW, Hofman A, Jansen PW, Tiemeier HW. Exploring the relation of harsh parental discipline with child emotional and behavioral problems by using multiple informants. The generation R study. Plos One. 9: e104793. PMID 25120014 DOI: 10.1371/Journal.Pone.0104793  0.589
2014 Rodenburg EM, Visser LE, Hoorn EJ, Ruiter R, Lous JJ, Hofman A, Uitterlinden AG, Stricker BH. Thiazides and the risk of hypokalemia in the general population. Journal of Hypertension. 32: 2092-7; discussion 2. PMID 25105457 DOI: 10.1097/Hjh.0000000000000299  0.307
2014 Qi Q, Kilpeläinen TO, Downer MK, Tanaka T, Smith CE, Sluijs I, Sonestedt E, Chu AY, Renström F, Lin X, Ängquist LH, Huang J, Liu Z, Li Y, Asif Ali M, ... ... Hofman A, et al. FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. Human Molecular Genetics. 23: 6961-72. PMID 25104851 DOI: 10.1093/Hmg/Ddu411  0.305
2014 Keller MF, Reiner AP, Okada Y, van Rooij FJ, Johnson AD, Chen MH, Smith AV, Morris AP, Tanaka T, Ferrucci L, Zonderman AB, Lettre G, Harris T, Garcia M, Bandinelli S, ... ... Hofman A, et al. Trans-ethnic meta-analysis of white blood cell phenotypes. Human Molecular Genetics. 23: 6944-60. PMID 25096241 DOI: 10.1093/hmg/ddu401  0.408
2014 Sabater-Lleal M, Mälarstig A, Folkersen L, Soler Artigas M, Baldassarre D, Kavousi M, Almgren P, Veglia F, Brusselle G, Hofman A, Engström G, Franco OH, Melander O, Paulsson-Berne G, Watkins H, et al. Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease. Plos One. 9: e104082. PMID 25093840 DOI: 10.1371/Journal.Pone.0104082  0.358
2014 Stergiakouli E, Gaillard R, Tavaré JM, Balthasar N, Loos RJ, Taal HR, Evans DM, Rivadeneira F, St Pourcain B, Uitterlinden AG, Kemp JP, Hofman A, Ring SM, Cole TJ, Jaddoe VW, et al. Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3. Obesity (Silver Spring, Md.). 22: 2252-9. PMID 25044758 DOI: 10.1002/Oby.20840  0.326
2014 van der Knaap NJ, El Marroun H, Klumpers F, Mous SE, Jaddoe VW, Hofman A, Homberg JR, White T, Tiemeier H, Fernández G. Beyond classical inheritance: the influence of maternal genotype upon child's brain morphology and behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 9516-21. PMID 25031395 DOI: 10.1523/Jneurosci.0505-14.2014  0.561
2014 van Rossem L, Hafkamp-de Groen E, Jaddoe VW, Hofman A, Mackenbach JP, Raat H. The role of early life factors in the development of ethnic differences in growth and overweight in preschool children: a prospective birth cohort. Bmc Public Health. 14: 722. PMID 25022314 DOI: 10.1186/1471-2458-14-722  0.302
2014 Holmes MV, Dale CE, Zuccolo L, Silverwood RJ, Guo Y, Ye Z, Prieto-Merino D, Dehghan A, Trompet S, Wong A, Cavadino A, Drogan D, Padmanabhan S, Li S, Yesupriya A, ... ... Hofman A, et al. Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. Bmj (Clinical Research Ed.). 349: g4164. PMID 25011450 DOI: 10.1136/Bmj.G4164  0.326
2014 Bolton JL, Hayward C, Direk N, Lewis JG, Hammond GL, Hill LA, Anderson A, Huffman J, Wilson JF, Campbell H, Rudan I, Wright A, Hastie N, Wild SH, Velders FP, ... Hofman A, et al. Genome wide association identifies common variants at the SERPINA6/SERPINA1 locus influencing plasma cortisol and corticosteroid binding globulin. Plos Genetics. 10: e1004474. PMID 25010111 DOI: 10.1371/Journal.Pgen.1004474  0.55
2014 Elfrink ME, Moll HA, Kiefte-de Jong JC, Jaddoe VW, Hofman A, ten Cate JM, Veerkamp JS. Pre- and postnatal determinants of deciduous molar hypomineralisation in 6-year-old children. The generation R study. Plos One. 9: e91057. PMID 24988443 DOI: 10.1371/Journal.Pone.0091057  0.302
2014 Tang W, Kowgier M, Loth DW, Soler Artigas M, Joubert BR, Hodge E, Gharib SA, Smith AV, Ruczinski I, Gudnason V, Mathias RA, Harris TB, Hansel NN, Launer LJ, Barnes KC, ... ... Hofman A, et al. Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function. Plos One. 9: e100776. PMID 24983941 DOI: 10.1371/Journal.Pone.0100776  0.317
2014 Kraja AT, Chasman DI, North KE, Reiner AP, Yanek LR, Kilpeläinen TO, Smith JA, Dehghan A, Dupuis J, Johnson AD, Feitosa MF, Tekola-Ayele F, Chu AY, Nolte IM, Dastani Z, ... ... Hofman A, et al. Pleiotropic genes for metabolic syndrome and inflammation. Molecular Genetics and Metabolism. 112: 317-38. PMID 24981077 DOI: 10.1016/J.Ymgme.2014.04.007  0.313
2014 Ganesh SK, Chasman DI, Larson MG, Guo X, Verwoert G, Bis JC, Gu X, Smith AV, Yang ML, Zhang Y, Ehret G, Rose LM, Hwang SJ, Papanicolau GJ, Sijbrands EJ, ... ... Hofman A, et al. Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. American Journal of Human Genetics. 95: 49-65. PMID 24975945 DOI: 10.1016/J.Ajhg.2014.06.002  0.475
2014 Bis JC, DeStefano A, Liu X, Brody JA, Choi SH, Verhaaren BF, Debette S, Ikram MA, Shahar E, Butler KR, Gottesman RF, Muzny D, Kovar CL, Psaty BM, Hofman A, et al. Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium. Plos One. 9: e99798. PMID 24959832 DOI: 10.1371/Journal.Pone.0099798  0.479
2014 Simino J, Shi G, Bis JC, Chasman DI, Ehret GB, Gu X, Guo X, Hwang SJ, Sijbrands E, Smith AV, Verwoert GC, Bragg-Gresham JL, Cadby G, Chen P, Cheng CY, ... ... Hofman A, et al. Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. American Journal of Human Genetics. 95: 24-38. PMID 24954895 DOI: 10.1016/J.Ajhg.2014.05.010  0.468
2014 Arking DE, Pulit SL, Crotti L, van der Harst P, Munroe PB, Koopmann TT, Sotoodehnia N, Rossin EJ, Morley M, Wang X, Johnson AD, Lundby A, Gudbjartsson DF, Noseworthy PA, Eijgelsheim M, ... ... Hofman A, et al. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nature Genetics. 46: 826-36. PMID 24952745 DOI: 10.1038/Ng.3014  0.449
2014 Lahousse L, Maes B, Ziere G, Loth DW, Verlinden VJ, Zillikens MC, Uitterlinden AG, Rivadeneira F, Tiemeier H, Franco OH, Ikram MA, Hofman A, Brusselle GG, Stricker BH. Adverse outcomes of frailty in the elderly: the Rotterdam Study. European Journal of Epidemiology. 29: 419-27. PMID 24935872 DOI: 10.1007/S10654-014-9924-1  0.571
2014 Ghassabian A, Steenweg-de Graaff J, Peeters RP, Ross HA, Jaddoe VW, Hofman A, Verhulst FC, White T, Tiemeier H. Maternal urinary iodine concentration in pregnancy and children's cognition: results from a population-based birth cohort in an iodine-sufficient area. Bmj Open. 4: e005520. PMID 24928597 DOI: 10.1136/Bmjopen-2014-005520  0.63
2014 Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, ... ... Hofman A, et al. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. Plos One. 9: e94661. PMID 24922517 DOI: 10.1371/Journal.Pone.0094661  0.616
2014 Korevaar TI, Steegers EA, Schalekamp-Timmermans S, Ligthart S, de Rijke YB, Visser WE, Visser W, de Muinck Keizer-Schrama SM, Hofman A, Hooijkaas H, Bongers-Schokking JJ, Russcher H, Tiemeier H, Jaddoe VW, Visser TJ, et al. Soluble Flt1 and placental growth factor are novel determinants of newborn thyroid (dys)function: the generation R study. The Journal of Clinical Endocrinology and Metabolism. 99: E1627-34. PMID 24885632 DOI: 10.1210/Jc.2014-1884  0.508
2014 Klein R, Myers CE, Buitendijk GH, Rochtchina E, Gao X, de Jong PT, Sivakumaran TA, Burlutsky G, McKean-Cowdin R, Hofman A, Iyengar SK, Lee KE, Stricker BH, Vingerling JR, Mitchell P, et al. Lipids, lipid genes, and incident age-related macular degeneration: the three continent age-related macular degeneration consortium. American Journal of Ophthalmology. 158: 513-24.e3. PMID 24879949 DOI: 10.1016/J.Ajo.2014.05.027  0.339
2014 Aarts N, Akoudad S, Noordam R, Hofman A, Ikram MA, Stricker BH, Visser LE, Vernooij MW. Inhibition of serotonin reuptake by antidepressants and cerebral microbleeds in the general population. Stroke; a Journal of Cerebral Circulation. 45: 1951-7. PMID 24876079 DOI: 10.1161/Strokeaha.114.004990  0.315
2014 White T, Muetzel R, Schmidt M, Langeslag SJ, Jaddoe V, Hofman A, Calhoun VD, Verhulst FC, Tiemeier H. Time of acquisition and network stability in pediatric resting-state functional magnetic resonance imaging. Brain Connectivity. 4: 417-27. PMID 24874884 DOI: 10.1089/Brain.2013.0195  0.597
2014 Jacobs LC, Liu F, Bleyen I, Gunn DA, Hofman A, Klaver CC, Uitterlinden AG, Neumann HA, Bataille V, Spector TD, Kayser M, Nijsten T. Intrinsic and extrinsic risk factors for sagging eyelids. Jama Dermatology. 150: 836-43. PMID 24869959 DOI: 10.1001/Jamadermatol.2014.27  0.353
2014 Gaillard R, Rurangirwa AA, Williams MA, Hofman A, Mackenbach JP, Franco OH, Steegers EA, Jaddoe VW. Maternal parity, fetal and childhood growth, and cardiometabolic risk factors. Hypertension. 64: 266-74. PMID 24866145 DOI: 10.1161/Hypertensionaha.114.03492  0.311
2014 de Bruijn RF, Akoudad S, Cremers LG, Hofman A, Niessen WJ, van der Lugt A, Koudstaal PJ, Vernooij MW, Ikram MA. Determinants, MRI correlates, and prognosis of mild cognitive impairment: the Rotterdam Study. Journal of Alzheimer's Disease : Jad. 42: S239-49. PMID 24825566 DOI: 10.1016/J.Jalz.2014.05.966  0.357
2014 de Bruijn RF, Janssen JA, Brugts MP, van Duijn CM, Hofman A, Koudstaal PJ, Ikram MA. Insulin-like growth factor-I receptor stimulating activity is associated with dementia. Journal of Alzheimer's Disease : Jad. 42: 137-42. PMID 24820016 DOI: 10.3233/Jad-140186  0.397
2014 Basten M, van der Ende J, Tiemeier H, Althoff RR, Rijlaarsdam J, Jaddoe VW, Hofman A, Hudziak JJ, Verhulst FC, White T. Nonverbal intelligence in young children with dysregulation: the Generation R Study. European Child & Adolescent Psychiatry. 23: 1061-70. PMID 24802760 DOI: 10.1007/S00787-014-0551-X  0.604
2014 Dierckx B, Kok R, Tulen JH, Jaddoe VW, Hofman A, Verhulst FC, Bakermans-Kranenburg MJ, van Ijzendoorn MH, Tiemeier H. A prospective study of heart rate and externalising behaviours in young children. Journal of Child Psychology and Psychiatry, and Allied Disciplines. 55: 402-10. PMID 24795956 DOI: 10.1016/J.Ijpsycho.2014.08.763  0.585
2014 Ferket BS, van Kempen BJ, Wieberdink RG, Steyerberg EW, Koudstaal PJ, Hofman A, Shahar E, Gottesman RF, Rosamond W, Kizer JR, Kronmal RA, Psaty BM, Longstreth WT, Mosley T, Folsom AR, et al. Separate prediction of intracerebral hemorrhage and ischemic stroke. Neurology. 82: 1804-12. PMID 24759844 DOI: 10.1212/Wnl.0000000000000427  0.341
2014 Rodriguez-Fontenla C, Calaza M, Evangelou E, Valdes AM, Arden N, Blanco FJ, Carr A, Chapman K, Deloukas P, Doherty M, Esko T, Garcés Aletá CM, Gomez-Reino Carnota JJ, Helgadottir H, Hofman A, et al. Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies. Arthritis & Rheumatology (Hoboken, N.J.). 66: 940-9. PMID 24757145 DOI: 10.1002/Art.38300  0.339
2014 de Bruijn RF, Direk N, Mirza SS, Hofman A, Koudstaal PJ, Tiemeier H, Ikram MA. Anxiety is not associated with the risk of dementia or cognitive decline: the Rotterdam Study. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 22: 1382-90. PMID 24745561 DOI: 10.1016/J.Jagp.2014.03.001  0.555
2014 Duvvari MR, Paun CC, Buitendijk GH, Saksens NT, Volokhina EB, Ristau T, Schoenmaker-Koller FE, van de Ven JP, Groenewoud JM, van den Heuvel LP, Hofman A, Fauser S, Uitterlinden AG, Klaver CC, Hoyng CB, et al. Analysis of rare variants in the C3 gene in patients with age-related macular degeneration. Plos One. 9: e94165. PMID 24736606 DOI: 10.1371/Journal.Pone.0094165  0.336
2014 Jusko TA, Shaw PA, Snijder CA, Pierik FH, Koch HM, Hauser R, Jaddoe VW, Burdorf A, Hofman A, Tiemeier H, Longnecker MP. Reproducibility of urinary bisphenol A concentrations measured during pregnancy in the Generation R Study. Journal of Exposure Science & Environmental Epidemiology. 24: 532-6. PMID 24736100 DOI: 10.1038/Jes.2014.23  0.519
2014 Adams HH, Verhaaren BF, Vrooman HA, Uitterlinden AG, Hofman A, van Duijn CM, van der Lugt A, Niessen WJ, Vernooij MW, Ikram MA. TMEM106B influences volume of left-sided temporal lobe and interhemispheric structures in the general population. Biological Psychiatry. 76: 503-8. PMID 24731779 DOI: 10.1016/J.Biopsych.2014.03.006  0.459
2014 Ghassabian A, Székely E, Herba CM, Jaddoe VW, Hofman A, Oldehinkel AJ, Verhulst FC, Tiemeier H. From positive emotionality to internalizing problems: the role of executive functioning in preschoolers. European Child & Adolescent Psychiatry. 23: 729-41. PMID 24728546 DOI: 10.1007/S00787-014-0542-Y  0.629
2014 Styrkarsdottir U, Thorleifsson G, Helgadottir HT, Bomer N, Metrustry S, Bierma-Zeinstra S, Strijbosch AM, Evangelou E, Hart D, Beekman M, Jonasdottir A, Sigurdsson A, Eiriksson FF, Thorsteinsdottir M, Frigge ML, ... ... Hofman A, et al. Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31. Nature Genetics. 46: 498-502. PMID 24728293 DOI: 10.1038/Ng.2957  0.325
2014 Brown ZA, Schalekamp-Timmermans S, Tiemeier HW, Hofman A, Jaddoe VW, Steegers EA. Fetal sex specific differences in human placentation: a prospective cohort study. Placenta. 35: 359-64. PMID 24720894 DOI: 10.1016/J.Placenta.2014.03.014  0.528
2014 Krijthe BP, Heeringa J, Hofman A, Franco OH, Stricker BH. Non-steroidal anti-inflammatory drugs and the risk of atrial fibrillation: a population-based follow-up study. Bmj Open. 4: e004059. PMID 24713211 DOI: 10.1136/Bmjopen-2013-004059  0.335
2014 Deelen J, Beekman M, Uh HW, Broer L, Ayers KL, Tan Q, Kamatani Y, Bennet AM, Tamm R, Trompet S, Guðbjartsson DF, Flachsbart F, Rose G, Viktorin A, Fischer K, ... ... Hofman A, et al. Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. Human Molecular Genetics. 23: 4420-32. PMID 24688116 DOI: 10.1093/Hmg/Ddu139  0.641
2014 Ghassabian A, El Marroun H, Peeters RP, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H, White T. Downstream effects of maternal hypothyroxinemia in early pregnancy: nonverbal IQ and brain morphology in school-age children. The Journal of Clinical Endocrinology and Metabolism. 99: 2383-90. PMID 24684462 DOI: 10.1210/Jc.2013-4281  0.618
2014 Kooijman MN, de Jonge LL, Steegers EA, van Osch-Gevers L, Verburg BO, Hofman A, Helbing WA, Jaddoe VW. Third trimester fetal hemodynamics and cardiovascular outcomes in childhood: the Generation R study. Journal of Hypertension. 32: 1275-82. PMID 24682032 DOI: 10.1097/Hjh.0000000000000174  0.304
2014 Kavousi M, Leening MJ, Nanchen D, Greenland P, Graham IM, Steyerberg EW, Ikram MA, Stricker BH, Hofman A, Franco OH. Comparison of application of the ACC/AHA guidelines, Adult Treatment Panel III guidelines, and European Society of Cardiology guidelines for cardiovascular disease prevention in a European cohort. Jama. 311: 1416-23. PMID 24681960 DOI: 10.1001/Jama.2014.2632  0.325
2014 Román GC, Ghassabian A, Bongers-Schokking JJ, Jaddoe VW, Hofman A, de Rijke YB, Verhulst FC, Tiemeier H. Reply: To PMID 23943579. Annals of Neurology. 75: 971-2. PMID 24644016 DOI: 10.1002/ana.24141  0.502
2014 Rijlaarsdam J, Stevens GW, Jansen PW, Ringoot AP, Jaddoe VW, Hofman A, Ayer L, Verhulst FC, Hudziak JJ, Tiemeier H. Maternal Childhood Maltreatment and Offspring Emotional and Behavioral Problems: Maternal and Paternal Mechanisms of Risk Transmission. Child Maltreatment. 19: 67-78. PMID 24642695 DOI: 10.1177/1077559514527639  0.619
2014 Aarts N, Noordam R, Hofman A, Tiemeier H, Stricker BH, Visser LE. Utilization patterns of antidepressants between 1991 and 2011 in a population-based cohort of middle-aged and elderly. European Psychiatry : the Journal of the Association of European Psychiatrists. 29: 365-70. PMID 24630746 DOI: 10.1016/J.Eurpsy.2014.02.001  0.534
2014 Bots ML, Groenewegen KA, Anderson TJ, Britton AR, Dekker JM, Engström G, Evans GW, de Graaf J, Grobbee DE, Hedblad B, Hofman A, Holewijn S, Ikeda A, Kavousi M, Kitagawa K, et al. Common carotid intima-media thickness measurements do not improve cardiovascular risk prediction in individuals with elevated blood pressure: the USE-IMT collaboration. Hypertension. 63: 1173-81. PMID 24614213 DOI: 10.1161/Hypertensionaha.113.02683  0.328
2014 Campos-Obando N, Castano-Betancourt MC, Oei L, Franco OH, Stricker BH, Brusselle GG, Lahousse L, Hofman A, Tiemeier H, Rivadeneira F, Uitterlinden AG, Zillikens MC. Bone mineral density and chronic lung disease mortality: the rotterdam study. The Journal of Clinical Endocrinology and Metabolism. 99: 1834-42. PMID 24606086 DOI: 10.1210/Jc.2013-3819  0.551
2014 Medici M, Porcu E, Pistis G, Teumer A, Brown SJ, Jensen RA, Rawal R, Roef GL, Plantinga TS, Vermeulen SH, Lahti J, Simmonds MJ, Husemoen LL, Freathy RM, Shields BM, ... ... Hofman A, et al. Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease. Plos Genetics. 10: e1004123. PMID 24586183 DOI: 10.1371/Journal.Pgen.1004123  0.355
2014 Huang J, Huffman JE, Yamakuchi M, Yamkauchi M, Trompet S, Asselbergs FW, Sabater-Lleal M, Trégouët DA, Chen WM, Smith NL, Kleber ME, Shin SY, Becker DM, Tang W, Dehghan A, ... ... Hofman A, et al. Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 1093-101. PMID 24578379 DOI: 10.1161/Atvbaha.113.302088  0.327
2014 Medici M, Direk N, Visser WE, Korevaar TI, Hofman A, Visser TJ, Tiemeier H, Peeters RP. Thyroid function within the normal range and the risk of depression: a population-based cohort study. The Journal of Clinical Endocrinology and Metabolism. 99: 1213-9. PMID 24564323 DOI: 10.1210/Jc.2013-3589  0.556
2014 Mirza SS, de Bruijn RF, Direk N, Hofman A, Koudstaal PJ, Ikram MA, Tiemeier H. Depressive symptoms predict incident dementia during short- but not long-term follow-up period. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S323-S329.e1. PMID 24530024 DOI: 10.1016/J.Jalz.2013.10.006  0.536
2014 Verlinden M, Tiemeier H, Veenstra R, Mieloo CL, Jansen W, Jaddoe VW, Raat H, Hofman A, Verhulst FC, Jansen PW. Television viewing through ages 2-5 years and bullying involvement in early elementary school. Bmc Public Health. 14: 157. PMID 24520886 DOI: 10.1186/1471-2458-14-157  0.627
2014 Oei L, Estrada K, Duncan EL, Christiansen C, Liu CT, Langdahl BL, Obermayer-Pietsch B, Riancho JA, Prince RL, van Schoor NM, McCloskey E, Hsu YH, Evangelou E, Ntzani E, Evans DM, ... ... Hofman A, et al. Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus. Bone. 59: 20-7. PMID 24516880 DOI: 10.1016/J.Bone.2013.10.015  0.313
2014 Verlinden M, Veenstra R, Ringoot AP, Jansen PW, Raat H, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Detecting bullying in early elementary school with a computerized peer-nomination instrument. Psychological Assessment. 26: 628-41. PMID 24512423 DOI: 10.1037/A0035571  0.586
2014 Tharner A, Jansen PW, Kiefte-de Jong JC, Moll HA, van der Ende J, Jaddoe VW, Hofman A, Tiemeier H, Franco OH. Toward an operative diagnosis of fussy/picky eating: a latent profile approach in a population-based cohort. The International Journal of Behavioral Nutrition and Physical Activity. 11: 14. PMID 24512388 DOI: 10.1186/1479-5868-11-14  0.521
2014 Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, ... ... Hofman A, et al. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature Genetics. 46: 234-44. PMID 24509480 DOI: 10.1038/Ng.2897  0.475
2014 Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang ZZ, Bizon C, Lange EM, Smith JD, Turner EH, Jun G, Kang HM, Peloso G, Auer P, Li KP, ... ... Hofman A, et al. Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. American Journal of Human Genetics. 94: 233-45. PMID 24507775 DOI: 10.1016/J.Ajhg.2014.01.010  0.452
2014 Peloso GM, Auer PL, Bis JC, Voorman A, Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M, Isaacs A, Jakobsdottir J, Feitosa MF, Davies G, Huffman JE, ... ... Hofman A, et al. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. American Journal of Human Genetics. 94: 223-32. PMID 24507774 DOI: 10.1016/J.Ajhg.2014.01.009  0.437
2014 Lubitz SA, Lunetta KL, Lin H, Arking DE, Trompet S, Li G, Krijthe BP, Chasman DI, Barnard J, Kleber ME, Dörr M, Ozaki K, Smith AV, Müller-Nurasyid M, Walter S, ... ... Hofman A, et al. Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese. Journal of the American College of Cardiology. 63: 1200-10. PMID 24486271 DOI: 10.1016/J.Jacc.2013.12.015  0.304
2014 Cents RA, Kok R, Tiemeier H, Lucassen N, Székely E, Bakermans-Kranenburg MJ, Hofman A, Jaddoe VW, van IJzendoorn MH, Verhulst FC, Lambregtse-van den Berg MP. Variations in maternal 5-HTTLPR affect observed sensitive parenting. Journal of Child Psychology and Psychiatry, and Allied Disciplines. 55: 1025-32. PMID 24484301 DOI: 10.1111/Jcpp.12205  0.596
2014 Selwaness M, van den Bouwhuijsen Q, Mattace-Raso FU, Verwoert GC, Hofman A, Franco OH, Witteman JC, van der Lugt A, Vernooij MW, Wentzel JJ. Arterial stiffness is associated with carotid intraplaque hemorrhage in the general population: the Rotterdam study. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 927-32. PMID 24482373 DOI: 10.1161/Atvbaha.113.302603  0.329
2014 Jaddoe VW, de Jonge LL, Hofman A, Franco OH, Steegers EA, Gaillard R. First trimester fetal growth restriction and cardiovascular risk factors in school age children: population based cohort study. Bmj (Clinical Research Ed.). 348: g14. PMID 24458585 DOI: 10.1136/Bmj.G14  0.332
2014 Székely E, Lucassen N, Tiemeier H, Bakermans-Kranenburg MJ, Van Ijzendoorn MH, Kok R, Jaddoe VW, Hofman A, Verhulst FC, Herba CM. Maternal depressive symptoms and sensitivity are related to young children's facial expression recognition: the Generation R Study. Development and Psychopathology. 26: 333-45. PMID 24439036 DOI: 10.1017/S0954579413001028  0.606
2014 van Kempen BJ, Ferket BS, Kavousi M, Leening MJ, Steyerberg EW, Ikram MA, Witteman JC, Hofman A, Franco OH, Hunink MG. Performance of Framingham cardiovascular disease (CVD) predictions in the Rotterdam Study taking into account competing risks and disentangling CVD into coronary heart disease (CHD) and stroke. International Journal of Cardiology. 171: 413-8. PMID 24438922 DOI: 10.1016/J.Ijcard.2013.12.036  0.326
2014 Ibrahim-Verbaas CA, Fornage M, Bis JC, Choi SH, Psaty BM, Meigs JB, Rao M, Nalls M, Fontes JD, O'Donnell CJ, Kathiresan S, Ehret GB, Fox CS, Malik R, Dichgans M, ... ... Hofman A, et al. Predicting stroke through genetic risk functions: the CHARGE Risk Score Project. Stroke; a Journal of Cerebral Circulation. 45: 403-12. PMID 24436238 DOI: 10.1161/Strokeaha.113.003044  0.459
2014 Moayyeri A, Hsu YH, Karasik D, Estrada K, Xiao SM, Nielson C, Srikanth P, Giroux S, Wilson SG, Zheng HF, Smith AV, Pye SR, Leo PJ, Teumer A, Hwang JY, ... ... Hofman A, et al. Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. Human Molecular Genetics. 23: 3054-68. PMID 24430505 DOI: 10.1093/Hmg/Ddt675  0.313
2014 Deelen J, Beekman M, Codd V, Trompet S, Broer L, Hägg S, Fischer K, Thijssen PE, Suchiman HE, Postmus I, Uitterlinden AG, Hofman A, de Craen AJ, Metspalu A, Pedersen NL, et al. Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers. International Journal of Epidemiology. 43: 878-86. PMID 24425829 DOI: 10.1093/Ije/Dyt267  0.485
2014 Székely E, Tiemeier H, Jansen PW, Jaddoe VW, Hofman A, Verhulst FC, Herba CM. Maternal depressive symptoms are associated with low fearfulness in preschoolers. Journal of Clinical Child and Adolescent Psychology : the Official Journal For the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53. 43: 791-8. PMID 24400706 DOI: 10.1080/15374416.2013.862800  0.619
2014 Godoy GA, Korevaar TI, Peeters RP, Hofman A, de Rijke YB, Bongers-Schokking JJ, Tiemeier H, Jaddoe VW, Gaillard R. Maternal thyroid hormones during pregnancy, childhood adiposity and cardiovascular risk factors: the Generation R Study. Clinical Endocrinology. 81: 117-25. PMID 24386874 DOI: 10.1111/Cen.12399  0.538
2014 Gaillard R, Steegers EA, Duijts L, Felix JF, Hofman A, Franco OH, Jaddoe VW. Childhood cardiometabolic outcomes of maternal obesity during pregnancy: the Generation R Study. Hypertension. 63: 683-91. PMID 24379180 DOI: 10.1161/Hypertensionaha.113.02671  0.308
2014 van der Voort EA, Koehler EM, Dowlatshahi EA, Hofman A, Stricker BH, Janssen HL, Schouten JN, Nijsten T. Psoriasis is independently associated with nonalcoholic fatty liver disease in patients 55 years old or older: Results from a population-based study. Journal of the American Academy of Dermatology. 70: 517-24. PMID 24373781 DOI: 10.1016/J.Jaad.2013.10.044  0.319
2014 Fowkes FG, Murray GD, Butcher I, Folsom AR, Hirsch AT, Couper DJ, Debacker G, Kornitzer M, Newman AB, Sutton-Tyrrell KC, Cushman M, Lee AJ, Price JF, D'Agostino RB, Murabito JM, ... ... Hofman A, et al. Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events. European Journal of Preventive Cardiology. 21: 310-20. PMID 24367001 DOI: 10.1177/2047487313516564  0.33
2014 Oei L, Hsu YH, Styrkarsdottir U, Eussen BH, de Klein A, Peters MJ, Halldorsson B, Liu CT, Alonso N, Kaptoge SK, Thorleifsson G, Hallmans G, Hocking LJ, Husted LB, Jameson KA, ... ... Hofman A, et al. A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. Journal of Medical Genetics. 51: 122-31. PMID 24343915 DOI: 10.1136/Jmedgenet-2013-102064  0.327
2014 Verlinden M, Veenstra R, Ghassabian A, Jansen PW, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Executive functioning and non-verbal intelligence as predictors of bullying in early elementary school. Journal of Abnormal Child Psychology. 42: 953-66. PMID 24337736 DOI: 10.1007/S10802-013-9832-Y  0.625
2014 van der Valk RJ, Duijts L, Timpson NJ, Salam MT, Standl M, Curtin JA, Genuneit J, Kerhof M, Kreiner-Møller E, Cáceres A, Gref A, Liang LL, Taal HR, Bouzigon E, Demenais F, ... ... Hofman A, et al. Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants. The Journal of Allergy and Clinical Immunology. 134: 46-55. PMID 24315451 DOI: 10.1016/J.Jaci.2013.08.053  0.406
2014 van Mil NH, Steegers-Theunissen RP, Bouwland-Both MI, Verbiest MM, Rijlaarsdam J, Hofman A, Steegers EA, Heijmans BT, Jaddoe VW, Verhulst FC, Stolk L, Eilers PH, Uitterlinden AG, Tiemeier H. DNA methylation profiles at birth and child ADHD symptoms. Journal of Psychiatric Research. 49: 51-9. PMID 24290898 DOI: 10.1016/J.Jpsychires.2013.10.017  0.6
2014 Wang JJ, Buitendijk GH, Rochtchina E, Lee KE, Klein BE, van Duijn CM, Flood VM, Meuer SM, Attia J, Myers C, Holliday EG, Tan AG, Smith WT, Iyengar SK, de Jong PT, ... Hofman A, et al. Genetic susceptibility, dietary antioxidants, and long-term incidence of age-related macular degeneration in two populations. Ophthalmology. 121: 667-75. PMID 24290803 DOI: 10.1016/J.Ophtha.2013.10.017  0.498
2014 Liu F, Hendriks AE, Ralf A, Boot AM, Benyi E, Sävendahl L, Oostra BA, van Duijn C, Hofman A, Rivadeneira F, Uitterlinden AG, Drop SL, Kayser M. Common DNA variants predict tall stature in Europeans. Human Genetics. 133: 587-97. PMID 24253421 DOI: 10.1007/S00439-013-1394-0  0.478
2014 Koehler EM, Sanna D, Hansen BE, van Rooij FJ, Heeringa J, Hofman A, Tiemeier H, Stricker BH, Schouten JN, Janssen HL. Serum liver enzymes are associated with all-cause mortality in an elderly population. Liver International : Official Journal of the International Association For the Study of the Liver. 34: 296-304. PMID 24219360 DOI: 10.1111/Liv.12311  0.521
2014 Portegies ML, de Bruijn RF, Hofman A, Koudstaal PJ, Ikram MA. Cerebral vasomotor reactivity and risk of mortality: the Rotterdam Study. Stroke; a Journal of Cerebral Circulation. 45: 42-7. PMID 24203842 DOI: 10.1161/Strokeaha.113.002348  0.324
2014 Iglesias AI, Springelkamp H, van der Linde H, Severijnen LA, Amin N, Oostra B, Kockx CE, van den Hout MC, van Ijcken WF, Hofman A, Uitterlinden AG, Verdijk RM, Klaver CC, Willemsen R, van Duijn CM. Exome sequencing and functional analyses suggest that SIX6 is a gene involved in an altered proliferation-differentiation balance early in life and optic nerve degeneration at old age. Human Molecular Genetics. 23: 1320-32. PMID 24150847 DOI: 10.1093/Hmg/Ddt522  0.459
2014 Felix JF, Voortman T, van den Hooven EH, Sajjad A, Leermakers ET, Tharner A, Kiefte-de Jong JC, Duijts L, Verhulst FC, de Jongste JC, Tiemeier H, Hofman A, Rivadeneira F, Moll HA, Raat H, et al. Health in children: a conceptual framework for use in healthy ageing research. Maturitas. 77: 47-51. PMID 24139819 DOI: 10.1016/J.Maturitas.2013.09.011  0.6
2014 El Marroun H, Schmidt MN, Franken IH, Jaddoe VW, Hofman A, van der Lugt A, Verhulst FC, Tiemeier H, White T. Prenatal tobacco exposure and brain morphology: a prospective study in young children. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 792-800. PMID 24096296 DOI: 10.1038/Npp.2013.273  0.615
2014 Kok R, Lucassen N, Bakermans-Kranenburg MJ, van IJzendoorn MH, Ghassabian A, Roza SJ, Govaert P, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Parenting, corpus callosum, and executive function in preschool children. Child Neuropsychology : a Journal On Normal and Abnormal Development in Childhood and Adolescence. 20: 583-606. PMID 24028215 DOI: 10.1080/09297049.2013.832741  0.607
2014 Evangelou E, Kerkhof HJ, Styrkarsdottir U, Ntzani EE, Bos SD, Esko T, Evans DS, Metrustry S, Panoutsopoulou K, Ramos YF, Thorleifsson G, Tsilidis KK, Arden N, Aslam N, ... ... Hofman A, et al. A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip. Annals of the Rheumatic Diseases. 73: 2130-6. PMID 23989986 DOI: 10.1136/Annrheumdis-2012-203114  0.31
2014 Guxens M, Voort AMMSd, Tiemeier H, Hofman A, Sunyer J, Jongste JCd, Jaddoe VWV, Duijts L. Parental psychological distress during pregnancy and wheezing in preschool children: the Generation R Study. The Journal of Allergy and Clinical Immunology. 133: 59-67. PMID 23777854 DOI: 10.1016/J.Jaci.2013.04.044  0.549
2014 Boomsma DI, Wijmenga C, Slagboom EP, Swertz MA, Karssen LC, Abdellaoui A, Ye K, Guryev V, Vermaat M, Van Dijk F, Francioli LC, Hottenga JJ, Laros JFJ, Li Q, Li Y, ... ... Hofman A, et al. The Genome of the Netherlands: Design, and project goals European Journal of Human Genetics. 22: 221-227. PMID 23714750 DOI: 10.1038/Ejhg.2013.118  0.447
2014 Steenweg-de Graaff J, Tiemeier H, Steegers-Theunissen RP, Hofman A, Jaddoe VW, Verhulst FC, Roza SJ. Maternal dietary patterns during pregnancy and child internalising and externalising problems. The Generation R Study. Clinical Nutrition (Edinburgh, Scotland). 33: 115-21. PMID 23541912 DOI: 10.1016/J.Clnu.2013.03.002  0.618
2014 Saridjan NS, Henrichs J, Schenk JJ, Jaddoe VW, Hofman A, Kirschbaum C, Verhulst FC, Tiemeier H. Diurnal cortisol rhythm and cognitive functioning in toddlers: the Generation R Study. Child Neuropsychology : a Journal On Normal and Abnormal Development in Childhood and Adolescence. 20: 210-29. PMID 23391483 DOI: 10.1080/09297049.2013.763921  0.635
2014 Sonneveld MAH, Maat Md, Portegies MLP, Hofman A, Turecek PL, Rottensteiner H, Scheiflinger F, Koudstaal PJ, Ikram MA, Leebeek F. Low ADAMTS13 Activity Is a Strong Risk Factor for Ischemic Stroke: A Prospective Cohort Study - the Rotterdam Study Blood. 124: 113-113. DOI: 10.1182/Blood.V124.21.113.113  0.314
2014 Székely E, Tiemeier H, Jaddoe VWV, Hofman A, Verhulst FC, Herba CM. Associations of internalizing and externalizing problems with facial expression recognition in preschoolers: The generation R study Social Development. 23: 611-630. DOI: 10.1111/Sode.12070  0.427
2014 Nikkelen SWC, Vossen HGM, Valkenburg PM, Velders FP, Windhorst DA, Jaddoe VWV, Hofman A, Verhulst FC, Tiemeier H. Media Violence and Children's ADHD-Related Behaviors: A Genetic Susceptibility Perspective Journal of Communication. 64: 42-60. DOI: 10.1111/Jcom.12073  0.605
2014 Rodenburg EM, Hofland J, Van Noord C, Visser LE, Dehghan A, Barbalic M, Jan Danser AH, Lawson KS, Hofman A, Witteman J, Boerwinkle E, Uitterlinden AG, Stricker BH, De Jong FH. Sex-specific differences in the effects of local androgen metabolism in the heart as an indicator for the risk of myocardial infarction Cardiovascular Endocrinology. 3: 134-141. DOI: 10.1097/Xce.0000000000000037  0.337
2014 Mirza SS, Tiemeier H, Bruijn RFAGd, Hofman A, Franco O, Jong Jd, Koudstaal P, Ikram MA. The Healthy Coffee-Drinker Effect: Different Short- And Long-Term Associations Between Coffee Intake And Dementia Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.04.491  0.52
2014 Mirza SS, Bruijn Rd, Tiemeier H, Koudstaal P, Meiracker Avd, Franco O, Hofman A, Ikram MA. Amino Terminal Pro B-Type Natriuretic Peptide In Relation To Cognitive Decline And Risk Of Dementia: The Rotterdam Study Alzheimers & Dementia. 10: 272. DOI: 10.1016/J.Jalz.2014.04.442  0.512
2014 Adams HHH, Bruijn RFAGd, Hofman A, Uitterlinden A, Duijn CV, Vernooij M, Koudstaal P, Ikram MA. Genetic Risk Of Neurodegenerative Diseases Is Associated With Mild Cognitive Impairment And Conversion To Dementia: The Rotterdam Study Alzheimers & Dementia. 10: 267. DOI: 10.1016/J.Jalz.2014.04.429  0.308
2013 Makurthou AA, Oei L, El Saddy S, Breda SJ, Castaño-Betancourt MC, Hofman A, van Meurs JB, Uitterlinden AG, Rivadeneira F, Oei EH. Scheuermann disease: evaluation of radiological criteria and population prevalence. Spine. 38: 1690-4. PMID 24509552 DOI: 10.1097/Brs.0B013E31829Ee8B7  0.313
2013 Bouwland-Both MI, van Mil NH, Stolk L, Eilers PH, Verbiest MM, Heijmans BT, Tiemeier H, Hofman A, Steegers EA, Jaddoe VW, Steegers-Theunissen RP. DNA methylation of IGF2DMR and H19 is associated with fetal and infant growth: the generation R study. Plos One. 8: e81731. PMID 24349121 DOI: 10.1371/Journal.Pone.0081731  0.528
2013 Sedaghat S, Hoorn EJ, van Rooij FJ, Hofman A, Franco OH, Witteman JC, Dehghan A. Serum uric acid and chronic kidney disease: the role of hypertension. Plos One. 8: e76827. PMID 24265674 DOI: 10.1371/Journal.Pone.0076827  0.322
2013 Hofman A, Darwish Murad S, van Duijn CM, Franco OH, Goedegebure A, Ikram MA, Klaver CC, Nijsten TE, Peeters RP, Stricker BH, Tiemeier HW, Uitterlinden AG, Vernooij MW. The Rotterdam Study: 2014 objectives and design update. European Journal of Epidemiology. 28: 889-926. PMID 24258680 DOI: 10.1007/s10654-013-9866-z  0.572
2013 Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, ... ... Hofman A, et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nature Genetics. 45: 1452-8. PMID 24162737 DOI: 10.1038/Ng.2802  0.555
2013 Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, MacGregor S, Verhoeven VJ, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St Pourcain B, Kemp JP, McMahon G, ... ... Hofman A, et al. Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. American Journal of Human Genetics. 93: 264-77. PMID 24144296 DOI: 10.1016/J.Ajhg.2013.06.016  0.427
2013 Verhoeven VJ, Buitendijk GH, Rivadeneira F, Uitterlinden AG, Vingerling JR, Hofman A, Klaver CC. Education influences the role of genetics in myopia. European Journal of Epidemiology. 28: 973-80. PMID 24142238 DOI: 10.1007/S10654-013-9856-1  0.312
2013 Gaillard R, Steegers EAP, Tiemeier H, Hofman A, Jaddoe VWV. Placental Vascular Dysfunction, Fetal and Childhood Growth, and Cardiovascular Development The Generation R Study Circulation. 128: 2202-2210. PMID 24135069 DOI: 10.1161/Circulationaha.113.003881  0.545
2013 Buitendijk GH, Rochtchina E, Myers C, van Duijn CM, Lee KE, Klein BE, Meuer SM, de Jong PT, Holliday EG, Tan AG, Uitterlinden AG, Sivakumaran TA, Sivakumaran TS, Attia J, Hofman A, et al. Prediction of age-related macular degeneration in the general population: the Three Continent AMD Consortium. Ophthalmology. 120: 2644-55. PMID 24120328 DOI: 10.1016/J.Ophtha.2013.07.053  0.503
2013 Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A, ... ... Hofman A, et al. Discovery and refinement of loci associated with lipid levels. Nature Genetics. 45: 1274-83. PMID 24097068 DOI: 10.1038/Ng.2797  0.46
2013 Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, ... ... Hofman A, et al. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature Genetics. 45: 1345-52. PMID 24097064 DOI: 10.1038/Ng.2795  0.462
2013 de Jonge LL, Langhout MA, Taal HR, Franco OH, Raat H, Hofman A, van Osch-Gevers L, Jaddoe VW. Infant feeding patterns are associated with cardiovascular structures and function in childhood. The Journal of Nutrition. 143: 1959-65. PMID 24089417 DOI: 10.3945/Jn.113.174326  0.328
2013 Darweesh SKL, Leening MJG, Akoudad S, Loth DW, Hofman A, Ikram MA, Vernooij MW, Stricker BH. Clopidogrel use is associated with an increased prevalence of cerebral microbleeds in a stroke-free population: the Rotterdam study. Journal of the American Heart Association. 2. PMID 24072532 DOI: 10.1161/Jaha.113.000359  0.363
2013 O'Seaghdha CM, Wu H, Yang Q, Kapur K, Guessous I, Zuber AM, Köttgen A, Stoudmann C, Teumer A, Kutalik Z, Mangino M, Dehghan A, Zhang W, Eiriksdottir G, Li G, ... ... Hofman A, et al. Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. Plos Genetics. 9: e1003796. PMID 24068962 DOI: 10.1371/Journal.Pgen.1003796  0.309
2013 van den Hooven EH, de Jonge LL, Kiefte-de Jong JC, Raat H, Villamor E, Hofman A, Felix JF, Jaddoe VW, Moll HA, Franco OH. Infant macronutrient composition is associated with differences in cardiovascular structures and function in childhood. The Journal of Nutrition. 143: 1989-98. PMID 24068791 DOI: 10.3945/Jn.113.179440  0.345
2013 Korevaar TI, Schalekamp-Timmermans S, de Rijke YB, Visser WE, Visser W, de Muinck Keizer-Schrama SM, Hofman A, Ross HA, Hooijkaas H, Tiemeier H, Bongers-Schokking JJ, Jaddoe VW, Visser TJ, Steegers EA, Medici M, et al. Hypothyroxinemia and TPO-antibody positivity are risk factors for premature delivery: the generation R study. The Journal of Clinical Endocrinology and Metabolism. 98: 4382-90. PMID 24037884 DOI: 10.1210/Jc.2013-2855  0.561
2013 Zhan X, Larson DE, Wang C, Koboldt DC, Sergeev YV, Fulton RS, Fulton LL, Fronick CC, Branham KE, Bragg-Gresham J, Jun G, Hu Y, Kang HM, Liu D, Othman M, ... ... Hofman A, et al. Identification of a rare coding variant in complement 3 associated with age-related macular degeneration. Nature Genetics. 45: 1375-9. PMID 24036949 DOI: 10.1038/Ng.2758  0.452
2013 Parsa A, Fuchsberger C, Köttgen A, O'Seaghdha CM, Pattaro C, de Andrade M, Chasman DI, Teumer A, Endlich K, Olden M, Chen MH, Tin A, Kim YJ, Taliun D, Li M, ... ... Hofman A, et al. Common variants in Mendelian kidney disease genes and their association with renal function. Journal of the American Society of Nephrology : Jasn. 24: 2105-17. PMID 24029420 DOI: 10.1681/Asn.2012100983  0.467
2013 Westra HJ, Peters MJ, Esko T, Yaghootkar H, Schurmann C, Kettunen J, Christiansen MW, Fairfax BP, Schramm K, Powell JE, Zhernakova A, Zhernakova DV, Veldink JH, Van den Berg LH, Karjalainen J, ... ... Hofman A, et al. Systematic identification of trans eQTLs as putative drivers of known disease associations. Nature Genetics. 45: 1238-43. PMID 24013639 DOI: 10.1038/Ng.2756  0.344
2013 Luijk MP, Mileva-Seitz VR, Jansen PW, van IJzendoorn MH, Jaddoe VW, Raat H, Hofman A, Verhulst FC, Tiemeier H. Ethnic differences in prevalence and determinants of mother-child bed-sharing in early childhood. Sleep Medicine. 14: 1092-9. PMID 23994270 DOI: 10.1016/J.Sleep.2013.04.019  0.61
2013 Medici M, Ghassabian A, Visser W, de Muinck Keizer-Schrama SM, Jaddoe VW, Visser WE, Hooijkaas H, Hofman A, Steegers EA, Bongers-Schokking JJ, Ross HA, Tiemeier H, Visser TJ, de Rijke YB, Peeters RP. Women with high early pregnancy urinary iodine levels have an increased risk of hyperthyroid newborns: the population-based Generation R Study. Clinical Endocrinology. 80: 598-606. PMID 23992400 DOI: 10.1111/Cen.12321  0.547
2013 Groen EH, Lingsma HF, Caudri D, Levie D, Wijga A, Koppelman GH, Duijts L, Jaddoe VWV, Smit HA, Kerkhof M, Moll HA, Hofman A, Steyerberg EW, Jongste JCd, Raat H. Predicting asthma in preschool children with asthma-like symptoms: Validating and updating the PIAMA risk score The Journal of Allergy and Clinical Immunology. 132: 1303-1310. PMID 23987795 DOI: 10.1016/J.Jaci.2013.07.007  0.302
2013 Luik AI, Zuurbier LA, Hofman A, Van Someren EJ, Tiemeier H. Stability and fragmentation of the activity rhythm across the sleep-wake cycle: the importance of age, lifestyle, and mental health. Chronobiology International. 30: 1223-30. PMID 23971909 DOI: 10.3109/07420528.2013.813528  0.523
2013 Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S, Rudnicka AR, Trompet S, Mälarstig A, Baumert J, Bis JC, ... ... Hofman A, et al. Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation. 128: 1310-24. PMID 23969696 DOI: 10.1161/Circulationaha.113.002251  0.352
2013 Flink IJ, Prins RG, Mackenbach JJ, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H, Raat H. Neighborhood ethnic diversity and behavioral and emotional problems in 3 year olds: results from the Generation R Study. Plos One. 8: e70070. PMID 23967068 DOI: 10.1371/Journal.Pone.0070070  0.618
2013 Román GC, Ghassabian A, Bongers-Schokking JJ, Jaddoe VW, Hofman A, de Rijke YB, Verhulst FC, Tiemeier H. Association of gestational maternal hypothyroxinemia and increased autism risk. Annals of Neurology. 74: 733-42. PMID 23943579 DOI: 10.1002/Ana.23976  0.644
2013 Ringoot AP, Jansen PW, Steenweg-de Graaff J, Measelle JR, van der Ende J, Raat H, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Young children's self-reported emotional, behavioral, and peer problems: the Berkeley Puppet Interview. Psychological Assessment. 25: 1273-85. PMID 23937536 DOI: 10.1037/A0033976  0.601
2013 de Keyser CE, Becker ML, Uitterlinden AG, Hofman A, Lous JJ, Elens L, Visser LE, van Schaik RH, Stricker BH. Genetic variation in the PPARA gene is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study. Pharmacogenomics. 14: 1295-304. PMID 23930676 DOI: 10.2217/Pgs.13.112  0.305
2013 Chowdhury R, Khan H, Heydon E, Shroufi A, Fahimi S, Moore C, Stricker B, Mendis S, Hofman A, Mant J, Franco OH. Adherence to cardiovascular therapy: a meta-analysis of prevalence and clinical consequences. European Heart Journal. 34: 2940-8. PMID 23907142 DOI: 10.1093/Eurheartj/Eht295  0.302
2013 Krijthe BP, Kunst A, Benjamin EJ, Lip GYH, Franco OH, Hofman A, Witteman JCM, Stricker BH, Heeringa J. Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060 European Heart Journal. 34: 2746-2751. PMID 23900699 DOI: 10.1093/Eurheartj/Eht280  0.311
2013 Basten MM, Althoff RR, Tiemeier H, Jaddoe VW, Hofman A, Hudziak JJ, Verhulst FC, van der Ende J. The dysregulation profile in young children: empirically defined classes in the Generation R study. Journal of the American Academy of Child and Adolescent Psychiatry. 52: 841-850.e2. PMID 23880494 DOI: 10.1016/J.Jaac.2013.05.007  0.607
2013 Korevaar TIM, Medici M, Rijke YBd, Visser W, Keizer-Schrama SMPFdM, Jaddoe VWV, Hofman A, Ross HA, Visser WE, Hooijkaas H, Steegers EAP, Tiemeier H, Bongers-Schokking JJ, Visser TJ, Peeters RP. Ethnic differences in maternal thyroid parameters during pregnancy: the Generation R study. The Journal of Clinical Endocrinology and Metabolism. 98: 3678-3686. PMID 23836936 DOI: 10.1210/Jc.2013-2005  0.523
2013 van Velsen EF, Vernooij MW, Vrooman HA, van der Lugt A, Breteler MM, Hofman A, Niessen WJ, Ikram MA. Brain cortical thickness in the general elderly population: the Rotterdam Scan Study. Neuroscience Letters. 550: 189-94. PMID 23831346 DOI: 10.1016/J.Neulet.2013.06.063  0.612
2013 van Meurs JB, Pare G, Schwartz SM, Hazra A, Tanaka T, Vermeulen SH, Cotlarciuc I, Yuan X, Mälarstig A, Bandinelli S, Bis JC, Blom H, Brown MJ, Chen C, Chen YD, ... ... Hofman A, et al. Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. The American Journal of Clinical Nutrition. 98: 668-76. PMID 23824729 DOI: 10.3945/Ajcn.112.044545  0.314
2013 Fall T, Hägg S, Mägi R, Ploner A, Fischer K, Horikoshi M, Sarin AP, Thorleifsson G, Ladenvall C, Kals M, Kuningas M, Draisma HH, Ried JS, van Zuydam NR, Huikari V, ... ... Hofman A, et al. The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis. Plos Medicine. 10: e1001474. PMID 23824655 DOI: 10.1371/Journal.Pmed.1001474  0.471
2013 Anttila V, Winsvold BS, Gormley P, Kurth T, Bettella F, McMahon G, Kallela M, Malik R, de Vries B, Terwindt G, Medland SE, Todt U, McArdle WL, Quaye L, Koiranen M, ... ... Hofman A, et al. Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nature Genetics. 45: 912-7. PMID 23793025 DOI: 10.1038/Ng.2676  0.469
2013 Sim X, Jensen RA, Ikram MK, Cotch MF, Li X, MacGregor S, Xie J, Smith AV, Boerwinkle E, Mitchell P, Klein R, Klein BE, Glazer NL, Lumley T, McKnight B, ... ... Hofman A, et al. Genetic loci for retinal arteriolar microcirculation. Plos One. 8: e65804. PMID 23776548 DOI: 10.1371/Journal.Pone.0065804  0.486
2013 Noordam R, Aarts N, Hofman A, Schaik RHNv, Stricker BH, Visser LE. Association between genetic variation in the ABCB1 gene and switching, discontinuation, and dosage of antidepressant therapy: results from the Rotterdam Study. Journal of Clinical Psychopharmacology. 33: 546-550. PMID 23771194 DOI: 10.1097/Jcp.0B013E318291C07B  0.323
2013 Isaacs A, Willems SM, Bos D, Dehghan A, Hofman A, Ikram MA, Uitterlinden AG, Oostra BA, Franco OH, Witteman JC, van Duijn CM. Risk scores of common genetic variants for lipid levels influence atherosclerosis and incident coronary heart disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2233-9. PMID 23766260 DOI: 10.1161/Atvbaha.113.301236  0.453
2013 Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, ... ... Hofman A, et al. Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. Plos Genetics. 9: e1003500. PMID 23754948 DOI: 10.1371/Journal.Pgen.1003500  0.443
2013 Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra HJ, Shakhbazov K, Abdellaoui A, Agrawal A, Albrecht E, Alizadeh BZ, Amin N, Barnard J, Baumeister SE, ... ... Hofman A, ... ... Hofman A, et al. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (New York, N.Y.). 340: 1467-71. PMID 23722424 DOI: 10.1126/Science.1235488  0.626
2013 van Batenburg-Eddes T, Henrichs J, Schenk JJ, Sincer I, de Groot L, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Early infant neuromotor assessment is associated with language and nonverbal cognitive function in toddlers: the Generation R Study. Journal of Developmental and Behavioral Pediatrics : Jdbp. 34: 326-34. PMID 23708382 DOI: 10.1097/Dbp.0B013E3182961E80  0.628
2013 van 't Hof FN, Ruigrok YM, Baas AF, Kiemeney LA, Vermeulen SH, Uitterlinden AG, Hofman A, Rivadeneira F, Rinkel GJ, de Bakker PI. Impact of inherited genetic variants associated with lipid profile, hypertension, and coronary artery disease on the risk of intracranial and abdominal aortic aneurysms. Circulation. Cardiovascular Genetics. 6: 264-70. PMID 23661678 DOI: 10.1161/Circgenetics.113.000022  0.359
2013 Mayerle J, den Hoed CM, Schurmann C, Stolk L, Homuth G, Peters MJ, Capelle LG, Zimmermann K, Rivadeneira F, Gruska S, Völzke H, de Vries AC, Völker U, Teumer A, van Meurs JB, ... ... Hofman A, et al. Identification of genetic loci associated with Helicobacter pylori serologic status. Jama. 309: 1912-20. PMID 23652523 DOI: 10.1001/Jama.2013.4350  0.307
2013 Tang W, Teichert M, Chasman DI, Heit JA, Morange PE, Li G, Pankratz N, Leebeek FW, Paré G, de Andrade M, Tzourio C, Psaty BM, Basu S, Ruiter R, Rose L, ... ... Hofman A, et al. A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Genetic Epidemiology. 37: 512-21. PMID 23650146 DOI: 10.1002/Gepi.21731  0.334
2013 Tanaka T, Ngwa JS, van Rooij FJ, Zillikens MC, Wojczynski MK, Frazier-Wood AC, Houston DK, Kanoni S, Lemaitre RN, Luan J, Mikkilä V, Renstrom F, Sonestedt E, Zhao JH, Chu AY, ... ... Hofman A, et al. Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. The American Journal of Clinical Nutrition. 97: 1395-402. PMID 23636237 DOI: 10.3945/Ajcn.112.052183  0.355
2013 Chain ASY, Dieleman JP, Noord Cv, Hofman A, Stricker BHC, Danhof M, Sturkenboom MCJM, Pasqua OD. Not-in-trial simulation I: Bridging cardiovascular risk from clinical trials to real-life conditions. British Journal of Clinical Pharmacology. 76: 964-972. PMID 23617533 DOI: 10.1111/Bcp.12151  0.317
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