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David M. A. Mann, PhD. FRCPath - Publications

Affiliations: 
Neuropathology University of Manchester, Manchester, England, United Kingdom 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=32
Website:
http://www.medicine.manchester.ac.uk/staff/77694

241 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Orme T, Hernandez D, Ross OA, Kun-Rodrigues C, Darwent L, Shepherd CE, Parkkinen L, Ansorge O, Clark L, Honig LS, Marder K, Lemstra A, Rogaeva E, St George-Hyslop P, Londos E, ... ... Mann D, et al. Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies. Acta Neuropathologica Communications. 8: 5. PMID 31996268 DOI: 10.1186/S40478-020-0879-Z  0.358
2019 Guerreiro R, Escott-Price V, Hernandez DG, Kun-Rodrigues C, Ross OA, Orme T, Neto JL, Carmona S, Dehghani N, Eicher JD, Shepherd C, Parkkinen L, Darwent L, Heckman MG, Scholz SW, ... ... Mann D, et al. Heritability and genetic variance of dementia with Lewy bodies. Neurobiology of Disease. PMID 30953760 DOI: 10.1016/J.Nbd.2019.04.004  0.38
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Mann D, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.302
2018 Graham SF, Pan X, Yilmaz A, Macias S, Robinson A, Mann D, Green BD. Targeted biochemical profiling of brain from Huntington's disease patients reveals novel metabolic pathways of interest. Biochimica Et Biophysica Acta. PMID 29684586 DOI: 10.1016/J.Bbadis.2018.04.012  0.357
2018 Guerreiro R, Ross OA, Kun-Rodrigues C, Hernandez DG, Orme T, Eicher JD, Shepherd CE, Parkkinen L, Darwent L, Heckman MG, Scholz SW, Troncoso JC, Pletnikova O, Ansorge O, Clarimon J, ... ... Mann D, et al. Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. The Lancet. Neurology. 17: 64-74. PMID 29263008 DOI: 10.1016/S1474-4422(17)30400-3  0.386
2017 Chaudhury S, Patel T, Barber IS, Guetta-Baranes T, Brookes KJ, Chappell S, Turton J, Guerreiro R, Bras J, Hernandez D, Singleton A, Hardy J, Mann D, Morgan K. Polygenic risk score in postmortem diagnosed sporadic early-onset Alzheimer's disease. Neurobiology of Aging. PMID 29103623 DOI: 10.1016/J.Neurobiolaging.2017.09.035  0.33
2017 Taipa R, Ferreira V, Brochado P, Robinson A, Reis I, Marques F, Mann DM, Melo Pires M, Sousa N. Inflammatory pathology markers (activated microglia and reactive astrocytes) in early and late onset Alzheimer disease: a post-mortem study. Neuropathology and Applied Neurobiology. PMID 29044639 DOI: 10.1111/Nan.12445  0.364
2017 Hosokawa M, Kondo H, Serrano GE, Beach TG, Robinson AC, Mann DM, Akiyama H, Hasegawa M, Arai T. Accumulation of multiple neurodegenerative disease-related proteins in familial frontotemporal lobar degeneration associated with granulin mutation. Scientific Reports. 7: 1513. PMID 28473694 DOI: 10.1038/s41598-017-01587-6  0.369
2017 Taipa R, Brochado P, Robinson A, Reis I, Costa P, Mann DM, Melo Pires M, Sousa N. Patterns of Microglial Cell Activation in Alzheimer Disease and Frontotemporal Lobar Degeneration. Neuro-Degenerative Diseases. 17: 145-154. PMID 28445885 DOI: 10.1159/000457127  0.349
2016 Kun-Rodrigues C, Ross OA, Orme T, Shepherd C, Parkkinen L, Darwent L, Hernandez D, Ansorge O, Clark LN, Honig LS, Marder K, Lemstra A, Scheltens P, van der Flier W, Louwersheimer E, ... ... Mann D, et al. Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies. Neurobiology of Aging. PMID 27666590 DOI: 10.1016/J.Neurobiolaging.2016.08.023  0.408
2016 Letronne F, Laumet G, Ayral AM, Chapuis J, Demiautte F, Laga M, Vandenberghe ME, Malmanche N, Leroux F, Eysert F, Sottejeau Y, Chami L, Flaig A, Bauer C, Dourlen P, ... ... Mann D, et al. ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease. Ebiomedicine. PMID 27333034 DOI: 10.1016/J.Ebiom.2016.06.002  0.419
2016 Behrouzi R, Liu X, Wu D, Robinson AC, Tanaguchi-Watanabe S, Rollinson S, Shi J, Tian J, Hamdalla HH, Ealing J, Richardson A, Jones M, Pickering-Brown S, Davidson YS, Strong MJ, ... ... Mann DM, et al. Pathological tau deposition in Motor Neurone Disease and frontotemporal lobar degeneration associated with TDP-43 proteinopathy. Acta Neuropathologica Communications. 4: 33. PMID 27036121 DOI: 10.1186/S40478-016-0301-Z  0.496
2016 Graham SF, Kumar P, Bahado-Singh RO, Robinson A, Mann D, Green BD. Novel Metabolite Biomarkers of Huntington's Disease As Detected by High-Resolution Mass Spectrometry. Journal of Proteome Research. PMID 27018767 DOI: 10.1021/Acs.Jproteome.6B00049  0.324
2015 Barber IS, García-Cárdenas JM, Sakdapanichkul C, Deacon C, Zapata Erazo G, Guerreiro R, Bras J, Hernandez D, Singleton A, Guetta-Baranes T, Braae A, Clement N, Patel T, Brookes K, Medway C, ... ... Mann DM, et al. Screening exons 16 and 17 of the amyloid precursor protein gene in sporadic early-onset Alzheimer's disease. Neurobiology of Aging. PMID 26803359 DOI: 10.1016/J.Neurobiolaging.2015.12.011  0.309
2015 Guerreiro R, Escott-Price V, Darwent L, Parkkinen L, Ansorge O, Hernandez DG, Nalls MA, Clark L, Honig L, Marder K, van der Flier W, Holstege H, Louwersheimer E, Lemstra A, Scheltens P, ... ... Mann D, et al. Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases. Neurobiology of Aging. PMID 26643944 DOI: 10.1016/J.Neurobiolaging.2015.10.028  0.414
2015 Lepelletier FX, Mann DM, Robinson AC, Pinteaux E, Boutin H. Early changes in extracellular matrix in Alzheimer's disease. Neuropathology and Applied Neurobiology. PMID 26544797 DOI: 10.1111/Nan.12295  0.414
2015 Davidson Y, Robinson AC, Liu X, Wu D, Troakes C, Rollinson S, Masuda-Suzukake M, Suzuki G, Nonaka T, Shi J, Tian J, Hamdalla H, Ealing J, Richardson A, Jones M, ... ... Mann DM, et al. Neurodegeneration in Frontotemporal Lobar Degeneration and Motor Neurone Disease associated with expansions in C9orf72 is linked to TDP-43 pathology and not associated with aggregated forms of dipeptide repeat proteins. Neuropathology and Applied Neurobiology. PMID 26538301 DOI: 10.1111/Nan.12292  0.409
2015 Taniguchi-Watanabe S, Arai T, Kametani F, Nonaka T, Masuda-Suzukake M, Tarutani A, Murayama S, Saito Y, Arima K, Yoshida M, Akiyama H, Robinson A, Mann DM, Iwatsubo T, Hasegawa M. Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau. Acta Neuropathologica. PMID 26538150 DOI: 10.1007/S00401-015-1503-3  0.429
2015 Luzzi S, Girelli F, Fiori C, Ranaldi V, Baldinelli S, Cameriere V, Silvestrini M, Provinciali L, Rollinson S, Pickering-Brown S, Mann D, Snowden JS. Left hand dystonia as a recurring feature of a family carrying C9ORF72 mutation. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 26187722 DOI: 10.1136/Jnnp-2015-311311  0.357
2015 Vaikath NN, Majbour NK, Paleologou KE, Ardah MT, van Dam E, van de Berg WD, Forrest SL, Parkkinen L, Gai WP, Hattori N, Takanashi M, Lee SJ, Mann DM, Imai Y, Halliday GM, et al. Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology. Neurobiology of Disease. 79: 81-99. PMID 25937088 DOI: 10.1016/J.Nbd.2015.04.009  0.335
2015 Rollinson S, Bennion Callister J, Young K, Ryan SJ, Druyeh R, Rohrer JD, Snowden J, Richardson A, Jones M, Harris J, Davidson Y, Robinson A, Ealing J, Johnson JO, Traynor B, ... ... Mann D, et al. A small deletion in C9orf72 hides a proportion of expansion carriers in FTLD. Neurobiology of Aging. 36: 1601.e1-5. PMID 25595499 DOI: 10.1016/J.Neurobiolaging.2014.12.009  0.338
2015 Mann DM. Dipeptide repeat protein toxicity in frontotemporal lobar degeneration and in motor neurone disease associated with expansions in C9ORF72-a cautionary note. Neurobiology of Aging. 36: 1224-6. PMID 25457023 DOI: 10.1016/J.Neurobiolaging.2014.10.011  0.333
2015 Gibbons L, Rollinson S, Thompson JC, Robinson A, Davidson YS, Richardson A, Neary D, Pickering-Brown SM, Snowden JS, Mann DM. Plasma levels of progranulin and interleukin-6 in frontotemporal lobar degeneration. Neurobiology of Aging. 36: 1603.e1-4. PMID 25435337 DOI: 10.1016/J.Neurobiolaging.2014.10.023  0.382
2015 Miller L, Rollinson S, Callister JB, Young K, Harris J, Gerhard A, Neary D, Richardson A, Snowden J, Mann DM, Pickering-Brown SM. p62/SQSTM1 analysis in frontotemporal lobar degeneration. Neurobiology of Aging. 36: 1603.e5-9. PMID 25433461 DOI: 10.1016/J.Neurobiolaging.2014.08.035  0.325
2015 Finelli D, Rollinson S, Harris J, Jones M, Richardson A, Gerhard A, Snowden J, Mann D, Pickering-Brown S. TREM2 analysis and increased risk of Alzheimer's disease. Neurobiology of Aging. 36: 546.e9-13. PMID 25260849 DOI: 10.1016/J.Neurobiolaging.2014.08.001  0.442
2015 Baborie A, Griffiths TD, Jaros E, Perry R, McKeith IG, Burn DJ, Masuda-Suzukake M, Hasegawa M, Rollinson S, Pickering-Brown S, Robinson AC, Davidson YS, Mann DM. Accumulation of dipeptide repeat proteins predates that of TDP-43 in frontotemporal lobar degeneration associated with hexanucleotide repeat expansions in C9ORF72 gene. Neuropathology and Applied Neurobiology. 41: 601-12. PMID 25185840 DOI: 10.1111/Nan.12178  0.343
2015 Ugwu F, Rollinson S, Harris J, Gerhard A, Richardson A, Jones M, Mann D, Snowden J, Pickering-Brown S. A UBQLN2 variant of unknown significance in frontotemporal lobar degeneration. Neurobiology of Aging. 36: 546.e15-6. PMID 25179229 DOI: 10.1016/J.Neurobiolaging.2014.08.002  0.337
2015 Harris JM, Thompson JC, Gall C, Richardson AM, Neary D, du Plessis D, Pal P, Mann DM, Snowden JS, Jones M. Do NIA-AA criteria distinguish Alzheimer's disease from frontotemporal dementia? Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 207-15. PMID 25022535 DOI: 10.1016/J.Jalz.2014.04.516  0.451
2015 Whitehouse A, Doherty K, Yeh HH, Robinson AC, Rollinson S, Pickering-Brown S, Snowden J, Thompson JC, Davidson YS, Mann DM. Histone deacetylases (HDACs) in frontotemporal lobar degeneration. Neuropathology and Applied Neurobiology. 41: 245-57. PMID 24861260 DOI: 10.1111/Nan.12153  0.349
2014 Bras J, Guerreiro R, Darwent L, Parkkinen L, Ansorge O, Escott-Price V, Hernandez DG, Nalls MA, Clark LN, Honig LS, Marder K, Van Der Flier WM, Lemstra A, Scheltens P, Rogaeva E, ... ... Mann D, et al. Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies. Human Molecular Genetics. 23: 6139-46. PMID 24973356 DOI: 10.1093/Hmg/Ddu334  0.435
2014 Davidson YS, Barker H, Robinson AC, Thompson JC, Harris J, Troakes C, Smith B, Al-Saraj S, Shaw C, Rollinson S, Masuda-Suzukake M, Hasegawa M, Pickering-Brown S, Snowden JS, Mann DM. Brain distribution of dipeptide repeat proteins in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72. Acta Neuropathologica Communications. 2: 70. PMID 24950788 DOI: 10.1186/2051-5960-2-70  0.352
2014 Ferrari R, Hernandez DG, Nalls MA, Rohrer JD, Ramasamy A, Kwok JB, Dobson-Stone C, Brooks WS, Schofield PR, Halliday GM, Hodges JR, Piguet O, Bartley L, Thompson E, Haan E, ... ... Mann DM, et al. Frontotemporal dementia and its subtypes: a genome-wide association study. The Lancet. Neurology. 13: 686-99. PMID 24943344 DOI: 10.1016/S1474-4422(14)70065-1  0.367
2014 Sassi C, Guerreiro R, Gibbs R, Ding J, Lupton MK, Troakes C, Lunnon K, Al-Sarraj S, Brown KS, Medway C, Lord J, Turton J, Mann D, Snowden J, Neary D, et al. Exome sequencing identifies 2 novel presenilin 1 mutations (p.L166V and p.S230R) in British early-onset Alzheimer's disease. Neurobiology of Aging. 35: 2422.e13-6. PMID 24880964 DOI: 10.1016/J.Neurobiolaging.2014.04.026  0.478
2014 Robinson AC, Thompson JC, Weedon L, Rollinson S, Pickering-Brown S, Snowden JS, Davidson YS, Mann DM. No interaction between tau and TDP-43 pathologies in either frontotemporal lobar degeneration or motor neurone disease. Neuropathology and Applied Neurobiology. 40: 844-54. PMID 24861427 DOI: 10.1111/Nan.12155  0.483
2014 Robinson A, Davidson Y, Snowden JS, Mann DM. C9ORF72 in dementia with Lewy bodies. Journal of Neurology, Neurosurgery, and Psychiatry. 85: 1435-6. PMID 24648039 DOI: 10.1136/Jnnp-2014-307622  0.386
2014 Cruchaga C, Karch CM, Jin SC, Benitez BA, Cai Y, Guerreiro R, Harari O, Norton J, Budde J, Bertelsen S, Jeng AT, Cooper B, Skorupa T, Carrell D, Levitch D, ... ... Mann DM, et al. Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease. Nature. 505: 550-4. PMID 24336208 DOI: 10.1038/Nature12825  0.312
2014 Hasegawa M, Watanabe S, Kondo H, Akiyama H, Mann DM, Saito Y, Murayama S. 3R and 4R tau isoforms in paired helical filaments in Alzheimer's disease. Acta Neuropathologica. 127: 303-5. PMID 24212601 DOI: 10.1007/S00401-013-1191-9  0.346
2014 Lant SB, Robinson AC, Thompson JC, Rollinson S, Pickering-Brown S, Snowden JS, Davidson YS, Gerhard A, Mann DM. Patterns of microglial cell activation in frontotemporal lobar degeneration. Neuropathology and Applied Neurobiology. 40: 686-96. PMID 24117616 DOI: 10.1111/Nan.12092  0.4
2014 Allen N, Robinson AC, Snowden J, Davidson YS, Mann DM. Patterns of cerebral amyloid angiopathy define histopathological phenotypes in Alzheimer's disease. Neuropathology and Applied Neurobiology. 40: 136-48. PMID 23808763 DOI: 10.1111/Nan.12070  0.431
2013 Dan A, Takahashi M, Masuda-Suzukake M, Kametani F, Nonaka T, Kondo H, Akiyama H, Arai T, Mann DM, Saito Y, Hatsuta H, Murayama S, Hasegawa M. Extensive deamidation at asparagine residue 279 accounts for weak immunoreactivity of tau with RD4 antibody in Alzheimer's disease brain. Acta Neuropathologica Communications. 1: 54. PMID 24252707 DOI: 10.1186/2051-5960-1-54  0.459
2013 Davidson YS, Robinson AC, Snowden JS, Mann DM. Pathological assessments for the presence of hexanucleotide repeat expansions in C9ORF72 in Alzheimer's disease. Acta Neuropathologica Communications. 1: 50. PMID 24252571 DOI: 10.1186/2051-5960-1-50  0.456
2013 Mann DM, Rollinson S, Robinson A, Bennion Callister J, Thompson JC, Snowden JS, Gendron T, Petrucelli L, Masuda-Suzukake M, Hasegawa M, Davidson Y, Pickering-Brown S. Dipeptide repeat proteins are present in the p62 positive inclusions in patients with frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72. Acta Neuropathologica Communications. 1: 68. PMID 24252525 DOI: 10.1186/2051-5960-1-68  0.355
2013 Harris JM, Gall C, Thompson JC, Richardson AM, Neary D, du Plessis D, Pal P, Mann DM, Snowden JS, Jones M. Classification and pathology of primary progressive aphasia. Neurology. 81: 1832-9. PMID 24142474 DOI: 10.1212/01.Wnl.0000436070.28137.7B  0.41
2013 Mann DM, Hardy J. Amyloid or tau: the chicken or the egg? Acta Neuropathologica. 126: 609-13. PMID 23925566 DOI: 10.1007/S00401-013-1162-1  0.375
2013 Nonaka T, Masuda-Suzukake M, Arai T, Hasegawa Y, Akatsu H, Obi T, Yoshida M, Murayama S, Mann DM, Akiyama H, Hasegawa M. Prion-like properties of pathological TDP-43 aggregates from diseased brains. Cell Reports. 4: 124-34. PMID 23831027 DOI: 10.1016/J.Celrep.2013.06.007  0.359
2013 Kasai T, Tokuda T, Taylor M, Kondo M, Mann DM, Foulds PG, Nakagawa M, Allsop D. Correlation of Aβ oligomer levels in matched cerebrospinal fluid and serum samples. Neuroscience Letters. 551: 17-22. PMID 23811027 DOI: 10.1016/J.Neulet.2013.06.029  0.348
2013 Harris JM, Gall C, Thompson JC, Richardson AM, Neary D, du Plessis D, Pal P, Mann DM, Snowden JS, Jones M. Sensitivity and specificity of FTDC criteria for behavioral variant frontotemporal dementia. Neurology. 80: 1881-7. PMID 23596080 DOI: 10.1212/Wnl.0B013E318292A342  0.391
2013 Nalls MA, Duran R, Lopez G, Kurzawa-Akanbi M, McKeith IG, Chinnery PF, Morris CM, Theuns J, Crosiers D, Cras P, Engelborghs S, De Deyn PP, Van Broeckhoven C, Mann DM, Snowden J, et al. A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies. Jama Neurology. 70: 727-35. PMID 23588557 DOI: 10.1001/Jamaneurol.2013.1925  0.375
2013 Snowden JS, Harris J, Richardson A, Rollinson S, Thompson JC, Neary D, Mann DM, Pickering-Brown S. Frontotemporal dementia with amyotrophic lateral sclerosis: a clinical comparison of patients with and without repeat expansions in C9orf72. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 172-6. PMID 23421625 DOI: 10.3109/21678421.2013.765485  0.337
2013 Yeh HH, Young D, Gelovani JG, Robinson A, Davidson Y, Herholz K, Mann DM. Histone deacetylase class II and acetylated core histone immunohistochemistry in human brains with Huntington's disease. Brain Research. 1504: 16-24. PMID 23419892 DOI: 10.1016/J.Brainres.2013.02.012  0.303
2013 Chapuis J, Hansmannel F, Gistelinck M, Mounier A, Van Cauwenberghe C, Kolen KV, Geller F, Sottejeau Y, Harold D, Dourlen P, Grenier-Boley B, Kamatani Y, Delepine B, Demiautte F, Zelenika D, ... ... Mann D, et al. Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology. Molecular Psychiatry. 18: 1225-34. PMID 23399914 DOI: 10.1038/Mp.2013.1  0.459
2013 Kobylecki C, Langheinrich T, Hinz R, Vardy ER, Martino M, Richardson AM, Snowden JS, Anton-Rodriguez J, Neary D, Mann DM, Gerhard A, Herholz K. A positron emission tomography study of [18f]-florbetapir in Alzheimer's disease and frontotemporal dementia. Journal of Neurology, Neurosurgery, and Psychiatry. 84. DOI: 10.1136/Jnnp-2013-306573.84  0.301
2012 Halliday G, Bigio EH, Cairns NJ, Neumann M, Mackenzie IR, Mann DM. Mechanisms of disease in frontotemporal lobar degeneration: gain of function versus loss of function effects. Acta Neuropathologica. 124: 373-82. PMID 22878865 DOI: 10.1007/S00401-012-1030-4  0.387
2012 Snowden JS, Rollinson S, Lafon C, Harris J, Thompson J, Richardson AM, Jones M, Gerhard A, Neary D, Mann DM, Pickering-Brown S. Psychosis, C9ORF72 and dementia with Lewy bodies. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 1031-2. PMID 22832738 DOI: 10.1136/Jnnp-2012-303032  0.405
2012 Rollinson S, Halliwell N, Young K, Callister JB, Toulson G, Gibbons L, Davidson YS, Robinson AC, Gerhard A, Richardson A, Neary D, Snowden J, Mann DM, Pickering-Brown SM. Analysis of the hexanucleotide repeat in C9ORF72 in Alzheimer's disease. Neurobiology of Aging. 33: 1846.e5-6. PMID 22410647 DOI: 10.1016/J.Neurobiolaging.2012.01.109  0.446
2012 Foulds P, Mann DM, Allsop D. Phosphorylated α-synuclein as a potential biomarker for Parkinson's disease and related disorders. Expert Review of Molecular Diagnostics. 12: 115-7. PMID 22369370 DOI: 10.1586/Erm.12.5  0.318
2012 Snowden JS, Rollinson S, Thompson JC, Harris JM, Stopford CL, Richardson AM, Jones M, Gerhard A, Davidson YS, Robinson A, Gibbons L, Hu Q, DuPlessis D, Neary D, Mann DM, et al. Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations. Brain : a Journal of Neurology. 135: 693-708. PMID 22300873 DOI: 10.1093/Brain/Awr355  0.413
2012 Luzzi S, Cafazzo V, Silvestrini M, Provinciali L, Pickering-Brown S, Mann D, Snowden JS. Semantic dementia associated with corticobasal syndrome: a further variant of frontotemporal lobe degeneration? Journal of Neurology. 259: 1478-80. PMID 22231872 DOI: 10.1007/S00415-011-6389-Y  0.333
2012 Gerrish A, Russo G, Richards A, Moskvina V, Ivanov D, Harold D, Sims R, Abraham R, Hollingworth P, Chapman J, Hamshere M, Pahwa JS, Dowzell K, Williams A, Jones N, ... ... Mann D, et al. The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 28: 377-87. PMID 22027014 DOI: 10.3233/Jad-2011-110824  0.465
2012 Foulds PG, Yokota O, Thurston A, Davidson Y, Ahmed Z, Holton J, Thompson JC, Akiyama H, Arai T, Hasegawa M, Gerhard A, Allsop D, Mann DM. Post mortem cerebrospinal fluid α-synuclein levels are raised in multiple system atrophy and distinguish this from the other α-synucleinopathies, Parkinson's disease and Dementia with Lewy bodies. Neurobiology of Disease. 45: 188-95. PMID 21856424 DOI: 10.1016/J.Nbd.2011.08.003  0.319
2012 Baborie A, Jaros E, Griffiths TD, Momeni P, Perry R, Mann DM. Frontotemporal lobar degeneration in a very young patient is associated with fused in sarcoma (FUS) pathological changes. Neuropathology and Applied Neurobiology. 38: 101-4. PMID 21726271 DOI: 10.1111/J.1365-2990.2011.01209.X  0.339
2012 Rollinson S, Bennion J, Toulson G, Halliwell N, Usher S, Snowden J, Richardson A, Neary D, Mann D, Pickering-Brown SM. Analysis of optineurin in frontotemporal lobar degeneration Neurobiology of Aging. 33: 425.e1-425.e2. PMID 21074902 DOI: 10.1016/J.Neurobiolaging.2010.10.002  0.318
2011 Davidson YS, Raby S, Foulds PG, Robinson A, Thompson JC, Sikkink S, Yusuf I, Amin H, DuPlessis D, Troakes C, Al-Sarraj S, Sloan C, Esiri MM, Prasher VP, Allsop D, ... ... Mann DM, et al. TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's syndrome: association with age, hippocampal sclerosis and clinical phenotype. Acta Neuropathologica. 122: 703-13. PMID 21968532 DOI: 10.1007/S00401-011-0879-Y  0.474
2011 Renton AE, Majounie E, Waite A, Simón-Sánchez J, Rollinson S, Gibbs JR, Schymick JC, Laaksovirta H, van Swieten JC, Myllykangas L, Kalimo H, Paetau A, Abramzon Y, Remes AM, Kaganovich A, ... ... Mann D, et al. A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron. 72: 257-68. PMID 21944779 DOI: 10.1016/J.Neuron.2011.09.010  0.359
2011 Williamson R, van Aalten L, Mann DM, Platt B, Plattner F, Bedford L, Mayer J, Howlett D, Usardi A, Sutherland C, Cole AR. CRMP2 hyperphosphorylation is characteristic of Alzheimer's disease and not a feature common to other neurodegenerative diseases. Journal of Alzheimer's Disease : Jad. 27: 615-25. PMID 21860090 DOI: 10.3233/Jad-2011-110617  0.467
2011 Snowden JS, Thompson JC, Stopford CL, Richardson AM, Gerhard A, Neary D, Mann DM. The clinical diagnosis of early-onset dementias: diagnostic accuracy and clinicopathological relationships. Brain : a Journal of Neurology. 134: 2478-92. PMID 21840888 DOI: 10.1093/Brain/Awr189  0.446
2011 Sims R, Dwyer S, Harold D, Gerrish A, Hollingworth P, Chapman J, Jones N, Abraham R, Ivanov D, Pahwa JS, Moskvina V, Dowzell K, Thomas C, Stretton A, Lovestone S, ... ... Mann D, et al. No evidence that extended tracts of homozygosity are associated with Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 764-71. PMID 21812096 DOI: 10.1002/Ajmg.B.31216  0.446
2011 Mackenzie IR, Neumann M, Baborie A, Sampathu DM, Du Plessis D, Jaros E, Perry RH, Trojanowski JQ, Mann DM, Lee VM. A harmonized classification system for FTLD-TDP pathology. Acta Neuropathologica. 122: 111-3. PMID 21644037 DOI: 10.1007/S00401-011-0845-8  0.375
2011 Josephs KA, Hodges JR, Snowden JS, Mackenzie IR, Neumann M, Mann DM, Dickson DW. Neuropathological background of phenotypical variability in frontotemporal dementia. Acta Neuropathologica. 122: 137-53. PMID 21614463 DOI: 10.1007/S00401-011-0839-6  0.333
2011 Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, ... ... Mann D, et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nature Genetics. 43: 429-35. PMID 21460840 DOI: 10.1038/Ng.803  0.313
2011 Snowden JS, Hu Q, Rollinson S, Halliwell N, Robinson A, Davidson YS, Momeni P, Baborie A, Griffiths TD, Jaros E, Perry RH, Richardson A, Pickering-Brown SM, Neary D, Mann DM. The most common type of FTLD-FUS (aFTLD-U) is associated with a distinct clinical form of frontotemporal dementia but is not related to mutations in the FUS gene. Acta Neuropathologica. 122: 99-110. PMID 21424531 DOI: 10.1007/S00401-011-0816-0  0.442
2011 Belbin O, Brown K, Shi H, Medway C, Abraham R, Passmore P, Mann D, Smith AD, Holmes C, McGuinness B, Craig D, Warden D, Heun R, Kölsch H, Love S, et al. A multi-center study of ACE and the risk of late-onset Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 24: 587-97. PMID 21297258 DOI: 10.3233/Jad-2011-101914  0.331
2011 Rollinson S, Mead S, Snowden J, Richardson A, Rohrer J, Halliwell N, Usher S, Neary D, Mann D, Hardy J, Pickering-Brown S. Frontotemporal lobar degeneration genome wide association study replication confirms a risk locus shared with amyotrophic lateral sclerosis. Neurobiology of Aging. 32: 758.e1-7. PMID 21257233 DOI: 10.1016/J.Neurobiolaging.2010.12.005  0.347
2011 Dakson A, Yokota O, Esiri M, Bigio EH, Horan M, Pendleton N, Richardson A, Neary D, Snowden JS, Robinson A, Davidson YS, Mann DM. Granular expression of prolyl-peptidyl isomerase PIN1 is a constant and specific feature of Alzheimer's disease pathology and is independent of tau, Aβ and TDP-43 pathology. Acta Neuropathologica. 121: 635-49. PMID 21243369 DOI: 10.1007/S00401-011-0798-Y  0.479
2011 Menon R, Baborie A, Jaros E, Mann DM, Ray PS, Larner AJ. What's in a name? Neuronal intermediate filament inclusion disease (NIFID), frontotemporal lobar degeneration-intermediate filament (FTLD-IF) or frontotemporal lobar degeneration-fused in sarcoma (FTLD-FUS)? Journal of Neurology, Neurosurgery, and Psychiatry. 82: 1412-4. PMID 21084263 DOI: 10.1136/Jnnp.2010.220947  0.376
2011 Connelly SJ, Mukaetova-Ladinska EB, Abdul-All Z, Alves da Silva J, Brayne C, Honer WG, Mann DM. Synaptic changes in frontotemporal lobar degeneration: correlation with MAPT haplotype and APOE genotype. Neuropathology and Applied Neurobiology. 37: 366-80. PMID 21073671 DOI: 10.1111/J.1365-2990.2010.01150.X  0.449
2011 Baborie A, Griffiths TD, Jaros E, McKeith IG, Burn DJ, Richardson A, Ferrari R, Moreno J, Momeni P, Duplessis D, Pal P, Rollinson S, Pickering-Brown S, Thompson JC, Neary D, ... ... Mann DM, et al. Pathological correlates of frontotemporal lobar degeneration in the elderly. Acta Neuropathologica. 121: 365-71. PMID 20978901 DOI: 10.1007/S00401-010-0765-Z  0.375
2011 Nishioka K, Ross OA, Vilariño-Güell C, Cobb SA, Kachergus JM, Mann DM, Snowden J, Richardson AM, Neary D, Robinson CA, Rajput A, Papapetropoulos S, Mash DC, Pahwa R, Lyons KE, et al. Glucocerebrosidase mutations in diffuse Lewy body disease. Parkinsonism & Related Disorders. 17: 55-7. PMID 20971030 DOI: 10.1016/J.Parkreldis.2010.09.009  0.375
2011 Rollinson S, Rohrer JD, van der Zee J, Sleegers K, Mead S, Engelborghs S, Collinge J, De Deyn PP, Mann DM, Van Broeckhoven C, Pickering-Brown SM. No association of PGRN 3'UTR rs5848 in frontotemporal lobar degeneration. Neurobiology of Aging. 32: 754-5. PMID 19446372 DOI: 10.1016/J.Neurobiolaging.2009.04.009  0.302
2010 Lambert JC, Sleegers K, González-Pérez A, Ingelsson M, Beecham GW, Hiltunen M, Combarros O, Bullido MJ, Brouwers N, Bettens K, Berr C, Pasquier F, Richard F, Dekosky ST, Hannequin D, ... ... Mann D, et al. The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study. Journal of Alzheimer's Disease : Jad. 22: 247-55. PMID 20847397 DOI: 10.3233/Jad-2010-100933  0.44
2010 Hansmannel F, Sillaire A, Kamboh MI, Lendon C, Pasquier F, Hannequin D, Laumet G, Mounier A, Ayral AM, DeKosky ST, Hauw JJ, Berr C, Mann D, Amouyel P, Campion D, et al. Is the urea cycle involved in Alzheimer's disease? Journal of Alzheimer's Disease : Jad. 21: 1013-21. PMID 20693631 DOI: 10.3233/Jad-2010-100630  0.433
2010 Yokota O, Davidson Y, Arai T, Hasegawa M, Akiyama H, Ishizu H, Terada S, Sikkink S, Pickering-Brown S, Mann DM. Effect of topographical distribution of α-synuclein pathology on TDP-43 accumulation in Lewy body disease. Acta Neuropathologica. 120: 789-801. PMID 20669025 DOI: 10.1007/S00401-010-0731-9  0.398
2010 Foulds P, Mann DM, Mitchell JD, Allsop D. Parkinson disease: Progress towards a molecular biomarker for Parkinson disease. Nature Reviews. Neurology. 6: 359-61. PMID 20639912 DOI: 10.1038/Nrneurol.2010.78  0.387
2010 Yokota O, Davidson Y, Bigio EH, Ishizu H, Terada S, Arai T, Hasegawa M, Akiyama H, Sikkink S, Pickering-Brown S, Mann DM. Phosphorylated TDP-43 pathology and hippocampal sclerosis in progressive supranuclear palsy. Acta Neuropathologica. 120: 55-66. PMID 20512649 DOI: 10.1007/S00401-010-0702-1  0.378
2010 Taylor M, Moore S, Mayes J, Parkin E, Beeg M, Canovi M, Gobbi M, Mann DM, Allsop D. Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease. Biochemistry. 49: 3261-72. PMID 20230062 DOI: 10.1021/Bi100144M  0.372
2010 Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature Genetics. 42: 234-9. PMID 20154673 DOI: 10.1038/Ng.536  0.355
2010 Mackenzie IR, Neumann M, Bigio EH, Cairns NJ, Alafuzoff I, Kril J, Kovacs GG, Ghetti B, Halliday G, Holm IE, Ince PG, Kamphorst W, Revesz T, Rozemuller AJ, Kumar-Singh S, ... ... Mann DM, et al. Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathologica. 119: 1-4. PMID 19924424 DOI: 10.1007/S00401-009-0612-2  0.333
2009 Foulds PG, Davidson Y, Mishra M, Hobson DJ, Humphreys KM, Taylor M, Johnson N, Weintraub S, Akiyama H, Arai T, Hasegawa M, Bigio EH, Benson FE, Allsop D, Mann DM. Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration. Acta Neuropathologica. 118: 647-58. PMID 19823856 DOI: 10.1007/S00401-009-0594-0  0.401
2009 Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, ... ... Mann D, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nature Genetics. 41: 1088-93. PMID 19734902 DOI: 10.1038/Ng.440  0.368
2009 Colombo R, Tavian D, Baker MC, Richardson AM, Snowden JS, Neary D, Mann DM, Pickering-Brown SM. Recent origin and spread of a common Welsh MAPT splice mutation causing frontotemporal lobar degeneration. Neurogenetics. 10: 313-8. PMID 19365643 DOI: 10.1007/S10048-009-0189-X  0.342
2009 Davidson Y, Amin H, Kelley T, Shi J, Tian J, Kumaran R, Lashley T, Lees AJ, DuPlessis D, Neary D, Snowden J, Akiyama H, Arai T, Hasegawa M, Bandopadhyay R, ... ... Mann DM, et al. TDP-43 in ubiquitinated inclusions in the inferior olives in frontotemporal lobar degeneration and in other neurodegenerative diseases: a degenerative process distinct from normal ageing. Acta Neuropathologica. 118: 359-69. PMID 19330339 DOI: 10.1007/S00401-009-0526-Z  0.417
2009 Rollinson S, Rizzu P, Sikkink S, Baker M, Halliwell N, Snowden J, Traynor BJ, Ruano D, Cairns N, Rohrer JD, Mead S, Collinge J, Rossor M, Akay E, Guerreiro R, ... ... Mann DM, et al. Ubiquitin associated protein 1 is a risk factor for frontotemporal lobar degeneration. Neurobiology of Aging. 30: 656-65. PMID 19217189 DOI: 10.1016/J.Neurobiolaging.2009.01.009  0.364
2009 Chapuis J, Hot D, Hansmannel F, Kerdraon O, Ferreira S, Hubans C, Maurage CA, Huot L, Bensemain F, Laumet G, Ayral AM, Fievet N, Hauw JJ, DeKosky ST, Lemoine Y, ... ... Mann D, et al. Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. Molecular Psychiatry. 14: 1004-16. PMID 19204726 DOI: 10.1038/Mp.2009.10  0.424
2009 Paleologou KE, Kragh CL, Mann DM, Salem SA, Al-Shami R, Allsop D, Hassan AH, Jensen PH, El-Agnaf OM. Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies. Brain : a Journal of Neurology. 132: 1093-101. PMID 19155272 DOI: 10.1093/Brain/Awn349  0.382
2009 Mackenzie IR, Neumann M, Bigio EH, Cairns NJ, Alafuzoff I, Kril J, Kovacs GG, Ghetti B, Halliday G, Holm IE, Ince PG, Kamphorst W, Revesz T, Rozemuller AJ, Kumar-Singh S, ... ... Mann DM, et al. Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations. Acta Neuropathologica. 117: 15-8. PMID 19015862 DOI: 10.1007/S00401-008-0460-5  0.334
2009 Kasai T, Tokuda T, Ishigami N, Sasayama H, Foulds P, Mitchell DJ, Mann DM, Allsop D, Nakagawa M. Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Acta Neuropathologica. 117: 55-62. PMID 18989684 DOI: 10.1007/S00401-008-0456-1  0.33
2009 Bensemain F, Hot D, Ferreira S, Dumont J, Bombois S, Maurage CA, Huot L, Hermant X, Levillain E, Hubans C, Hansmannel F, Chapuis J, Hauw JJ, Schraen S, Lemoine Y, ... ... Mann D, et al. Evidence for induction of the ornithine transcarbamylase expression in Alzheimer's disease. Molecular Psychiatry. 14: 106-16. PMID 17893704 DOI: 10.1038/Sj.Mp.4002089  0.424
2008 Dreses-Werringloer U, Lambert JC, Vingtdeux V, Zhao H, Vais H, Siebert A, Jain A, Koppel J, Rovelet-Lecrux A, Hannequin D, Pasquier F, Galimberti D, Scarpini E, Mann D, Lendon C, et al. A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk. Cell. 133: 1149-61. PMID 18585350 DOI: 10.1016/J.Cell.2008.05.048  0.402
2008 Foulds P, McAuley E, Gibbons L, Davidson Y, Pickering-Brown SM, Neary D, Snowden JS, Allsop D, Mann DM. TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration. Acta Neuropathologica. 116: 141-6. PMID 18506455 DOI: 10.1007/S00401-008-0389-8  0.428
2008 Chapuis J, Hannequin D, Pasquier F, Bentham P, Brice A, Leber I, Frebourg T, Deleuze JF, Cousin E, Thaker U, Amouyel P, Mann D, Lendon C, Campion D, Lambert JC. Association study of the GAB2 gene with the risk of developing Alzheimer's disease. Neurobiology of Disease. 30: 103-6. PMID 18272374 DOI: 10.1016/J.Nbd.2007.12.006  0.439
2008 Pickering-Brown SM, Rollinson S, Du Plessis D, Morrison KE, Varma A, Richardson AM, Neary D, Snowden JS, Mann DM. Frequency and clinical characteristics of progranulin mutation carriers in the Manchester frontotemporal lobar degeneration cohort: comparison with patients with MAPT and no known mutations. Brain : a Journal of Neurology. 131: 721-31. PMID 18192287 DOI: 10.1093/Brain/Awm331  0.377
2008 Bowen DM, Procter AW, Mann DM, Snowden JS, Esiri MM, Neary D, Francis PT. Imbalance of a serotonergic system in frontotemporal dementia: implication for pharmacotherapy. Psychopharmacology. 196: 603-10. PMID 18026720 DOI: 10.1007/S00213-007-0992-8  0.432
2008 Belbin O, Dunn JL, Chappell S, Ritchie AE, Ling Y, Morgan L, Pritchard A, Warden DR, Lendon CL, Lehmann DJ, Mann DM, Smith AD, Kalsheker N, Morgan K. A SNP in the ACT gene associated with astrocytosis and rapid cognitive decline in AD. Neurobiology of Aging. 29: 1167-76. PMID 17368652 DOI: 10.1016/J.Neurobiolaging.2007.02.021  0.356
2008 Rollinson SJ, Sikkink SK, Halliwell NA, Rizzu PR, Heutink P, Swieten JV, Mann D, Pickering-Brown S. P2-106: UBAP1 is a risk factor for frontotemporal lobar degeneration Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1180  0.363
2008 Iwata N, Tsubuki S, Higuchi M, Watanabe K, Staufenbiel M, Mann DM, Saido TC. P1-434: Accumulation of Aβ starting with pyroglutamate at position 3 in the brain and its impact on amyloid pathology of Alzheimer's disease Alzheimer's & Dementia. 4: T346-T347. DOI: 10.1016/J.Jalz.2008.05.1016  0.44
2007 Snowden JS, Pickering-Brown SM, Du Plessis D, Mackenzie IR, Varma A, Mann DM, Neary D. Progressive anomia revisited: focal degeneration associated with progranulin gene mutation. Neurocase. 13: 366-77. PMID 18781435 DOI: 10.1080/13554790701851510  0.39
2007 Snowden JS, Stopford CL, Julien CL, Thompson JC, Davidson Y, Gibbons L, Pritchard A, Lendon CL, Richardson AM, Varma A, Neary D, Mann D. Cognitive phenotypes in Alzheimer's disease and genetic risk. Cortex; a Journal Devoted to the Study of the Nervous System and Behavior. 43: 835-45. PMID 17941342 DOI: 10.1016/S0010-9452(08)70683-X  0.448
2007 Doran M, du Plessis DG, Ghadiali EJ, Mann DM, Pickering-Brown S, Larner AJ. Familial early-onset dementia with tau intron 10 + 16 mutation with clinical features similar to those of Alzheimer disease. Archives of Neurology. 64: 1535-9. PMID 17923640 DOI: 10.1001/Archneur.64.10.1535  0.464
2007 Rademakers R, Baker M, Gass J, Adamson J, Huey ED, Momeni P, Spina S, Coppola G, Karydas AM, Stewart H, Johnson N, Hsiung GY, Kelley B, Kuntz K, Steinbart E, ... ... Mann D, et al. Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative. The Lancet. Neurology. 6: 857-68. PMID 17826340 DOI: 10.1016/S1474-4422(07)70221-1  0.311
2007 Kumaran R, Kingsbury A, Coulter I, Lashley T, Williams D, de Silva R, Mann D, Revesz T, Lees A, Bandopadhyay R. DJ-1 (PARK7) is associated with 3R and 4R tau neuronal and glial inclusions in neurodegenerative disorders. Neurobiology of Disease. 28: 122-32. PMID 17719794 DOI: 10.1016/J.Nbd.2007.07.012  0.446
2007 Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, ... ... Mann DM, et al. Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathologica. 114: 5-22. PMID 17579875 DOI: 10.1007/S00401-007-0237-2  0.453
2007 Lambert JC, Ferreira S, Gussekloo J, Christiansen L, Brysbaert G, Slagboom E, Cottel D, Petit T, Hauw JJ, DeKosky ST, Richard F, Berr C, Lendon C, Kamboh MI, Mann D, et al. Evidence for the association of the S100beta gene with low cognitive performance and dementia in the elderly. Molecular Psychiatry. 12: 870-80. PMID 17579612 DOI: 10.1038/Sj.Mp.4001974  0.391
2007 Mann D. Frontotemporal lobar degeneration--a coming of age. Acta Neuropathologica. 114: 1-4. PMID 17572899 DOI: 10.1007/S00401-007-0245-2  0.471
2007 Snowden J, Neary D, Mann D. Frontotemporal lobar degeneration: clinical and pathological relationships. Acta Neuropathologica. 114: 31-8. PMID 17569065 DOI: 10.1007/S00401-007-0236-3  0.315
2007 Shepherd CE, Grace EM, Mann DM, Halliday GM. Relationship between neuronal loss and 'inflammatory plaques' in early onset Alzheimer's disease. Neuropathology and Applied Neurobiology. 33: 328-33. PMID 17493013 DOI: 10.1111/J.1365-2990.2006.00816.X  0.391
2007 Rollinson S, Snowden JS, Neary D, Morrison KE, Mann DM, Pickering-Brown SM. TDP-43 gene analysis in frontotemporal lobar degeneration. Neuroscience Letters. 419: 1-4. PMID 17434264 DOI: 10.1016/J.Neulet.2007.03.044  0.384
2007 Boddaert J, Kinugawa K, Lambert JC, Boukhtouche F, Zoll J, Merval R, Blanc-Brude O, Mann D, Berr C, Vilar J, Garabedian B, Journiac N, Charue D, Silvestre JS, Duyckaerts C, et al. Evidence of a role for lactadherin in Alzheimer's disease. The American Journal of Pathology. 170: 921-9. PMID 17322377 DOI: 10.2353/Ajpath.2007.060664  0.436
2007 Davidson Y, Kelley T, Mackenzie IR, Pickering-Brown S, Du Plessis D, Neary D, Snowden JS, Mann DM. Ubiquitinated pathological lesions in frontotemporal lobar degeneration contain the TAR DNA-binding protein, TDP-43. Acta Neuropathologica. 113: 521-33. PMID 17219193 DOI: 10.1007/S00401-006-0189-Y  0.333
2007 Davidson Y, Gibbons L, Pritchard A, Hardicre J, Wren J, Stopford C, Julien C, Thompson J, Payton A, Pickering-Brown SM, Pendleton N, Horan MA, Burns A, Purandare N, Lendon CL, ... ... Mann DM, et al. Apolipoprotein E epsilon4 allele frequency and age at onset of Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 23: 60-6. PMID 17108687 DOI: 10.1159/000097038  0.372
2006 Momeni P, Bell J, Duckworth J, Hutton M, Mann D, Brown SP, Hardy J. Sequence analysis of all identified open reading frames on the frontal temporal dementia haplotype on chromosome 3 fails to identify unique coding variants except in CHMP2B. Neuroscience Letters. 410: 77-9. PMID 17095158 DOI: 10.1016/J.Neulet.2006.06.065  0.4
2006 Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, Mori H, Mann D, Tsuchiya K, Yoshida M, Hashizume Y, Oda T. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochemical and Biophysical Research Communications. 351: 602-11. PMID 17084815 DOI: 10.1016/J.Bbrc.2006.10.093  0.379
2006 Pickering-Brown SM, Baker M, Gass J, Boeve BF, Loy CT, Brooks WS, Mackenzie IR, Martins RN, Kwok JB, Halliday GM, Kril J, Schofield PR, Mann DM, Hutton M. Mutations in progranulin explain atypical phenotypes with variants in MAPT. Brain : a Journal of Neurology. 129: 3124-6. PMID 17071927 DOI: 10.1093/Brain/Awl289  0.375
2006 Mackenzie IR, Baborie A, Pickering-Brown S, Du Plessis D, Jaros E, Perry RH, Neary D, Snowden JS, Mann DM. Heterogeneity of ubiquitin pathology in frontotemporal lobar degeneration: classification and relation to clinical phenotype. Acta Neuropathologica. 112: 539-49. PMID 17021754 DOI: 10.1007/S00401-006-0138-9  0.389
2006 Snowden JS, Pickering-Brown SM, Mackenzie IR, Richardson AM, Varma A, Neary D, Mann DM. Progranulin gene mutations associated with frontotemporal dementia and progressive non-fluent aphasia. Brain : a Journal of Neurology. 129: 3091-102. PMID 17003069 DOI: 10.1093/Brain/Awl267  0.308
2006 Purandare N, Oude Voshaar RC, Davidson Y, Gibbons L, Hardicre J, Byrne J, McCollum C, Jackson A, Burns A, Mann DM. Deletion/insertion polymorphism of the angiotensin-converting enzyme gene and white matter hyperintensities in dementia: A pilot study. Journal of the American Geriatrics Society. 54: 1395-400. PMID 16970648 DOI: 10.1111/J.1532-5415.2006.00841.X  0.412
2006 Mackenzie IR, Shi J, Shaw CL, Duplessis D, Neary D, Snowden JS, Mann DM. Dementia lacking distinctive histology (DLDH) revisited. Acta Neuropathologica. 112: 551-9. PMID 16900341 DOI: 10.1007/S00401-006-0123-3  0.371
2006 Shiarli AM, Jennings R, Shi J, Bailey K, Davidson Y, Tian J, Bigio EH, Ghetti B, Murrell JR, Delisle MB, Mirra S, Crain B, Zolo P, Arima K, Iseki E, ... ... Mann DM, et al. Comparison of extent of tau pathology in patients with frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17), frontotemporal lobar degeneration with Pick bodies and early onset Alzheimer's disease. Neuropathology and Applied Neurobiology. 32: 374-87. PMID 16866983 DOI: 10.1111/J.1365-2990.2006.00736.X  0.47
2006 Liu K, Solano I, Mann D, Lemere C, Mercken M, Trojanowski JQ, Lee VM. Characterization of Abeta11-40/42 peptide deposition in Alzheimer's disease and young Down's syndrome brains: implication of N-terminally truncated Abeta species in the pathogenesis of Alzheimer's disease. Acta Neuropathologica. 112: 163-74. PMID 16865398 DOI: 10.1007/S00401-006-0077-5  0.375
2006 Baker M, Mackenzie IR, Pickering-Brown SM, Gass J, Rademakers R, Lindholm C, Snowden J, Adamson J, Sadovnick AD, Rollinson S, Cannon A, Dwosh E, Neary D, Melquist S, Richardson A, ... ... Mann D, et al. Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. Nature. 442: 916-9. PMID 16862116 DOI: 10.1038/Nature05016  0.445
2006 Davidson Y, Gibbons L, Purandare N, Byrne J, Hardicre J, Wren J, Payton A, Pendleton N, Horan M, Burns A, Mann DM. Apolipoprotein E epsilon4 allele frequency in vascular dementia. Dementia and Geriatric Cognitive Disorders. 22: 15-9. PMID 16645276 DOI: 10.1159/000092960  0.317
2006 Tian J, Shi J, Smallman R, Iwatsubo T, Mann DM. Relationships in Alzheimer's disease between the extent of Abeta deposition in cerebral blood vessel walls, as cerebral amyloid angiopathy, and the amount of cerebrovascular smooth muscle cells and collagen. Neuropathology and Applied Neurobiology. 32: 332-40. PMID 16640651 DOI: 10.1111/J.1365-2990.2006.00732.X  0.364
2006 de Silva R, Lashley T, Strand C, Shiarli AM, Shi J, Tian J, Bailey KL, Davies P, Bigio EH, Arima K, Iseki E, Murayama S, Kretzschmar H, Neumann M, Lippa C, ... ... Mann DM, et al. An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies. Acta Neuropathologica. 111: 329-40. PMID 16552612 DOI: 10.1007/S00401-006-0048-X  0.404
2006 Davidson Y, Gibbons L, Pritchard A, Hardicre J, Wren J, Tian J, Shi J, Stopford C, Julien C, Thompson J, Payton A, Thaker U, Hayes AJ, Iwatsubo T, Pickering-Brown SM, ... ... Mann DM, et al. Genetic associations between cathepsin D exon 2 C-->T polymorphism and Alzheimer's disease, and pathological correlations with genotype. Journal of Neurology, Neurosurgery, and Psychiatry. 77: 515-7. PMID 16543533 DOI: 10.1136/Jnnp.2005.063917  0.46
2006 Bensemain F, Chapuis J, Tian J, Shi J, Thaker U, Lendon C, Iwatsubo T, Amouyel P, Mann D, Lambert JC. Association study of the Ubiquilin gene with Alzheimer's disease. Neurobiology of Disease. 22: 691-3. PMID 16504527 DOI: 10.1016/J.Nbd.2006.01.007  0.438
2006 van Leeuwen FW, van Tijn P, Sonnemans MA, Hobo B, Mann DM, Van Broeckhoven C, Kumar-Singh S, Cras P, Leuba G, Savioz A, Maat-Schieman ML, Yamaguchi H, Kros JM, Kamphorst W, Hol EM, et al. Frameshift proteins in autosomal dominant forms of Alzheimer disease and other tauopathies. Neurology. 66: S86-92. PMID 16432153 DOI: 10.1212/01.Wnl.0000193882.46003.6D  0.479
2006 Cannon A, Baker M, Boeve B, Josephs K, Knopman D, Petersen R, Parisi J, Dickison D, Adamson J, Snowden J, Neary D, Mann D, Hutton M, Pickering-Brown SM. CHMP2B mutations are not a common cause of frontotemporal lobar degeneration. Neuroscience Letters. 398: 83-4. PMID 16431024 DOI: 10.1016/J.Neulet.2005.12.056  0.344
2006 Shi J, Tian J, Pritchard A, Lendon C, Lambert JC, Iwatsubo T, Mann DM. A 3'-UTR polymorphism in the oxidized LDL receptor 1 gene increases Abeta40 load as cerebral amyloid angiopathy in Alzheimer's disease. Acta Neuropathologica. 111: 15-20. PMID 16328515 DOI: 10.1007/S00401-005-1108-3  0.415
2006 Chapuis J, Tian J, Shi J, Bensemain F, Cottel D, Lendon C, Amouyel P, Mann D, Lambert JC. Association study of the vascular endothelial growth factor gene with the risk of developing Alzheimer's disease. Neurobiology of Aging. 27: 1212-5. PMID 16154235 DOI: 10.1016/J.Neurobiolaging.2005.07.013  0.406
2005 Neary D, Snowden J, Mann D. Frontotemporal dementia. The Lancet. Neurology. 4: 771-80. PMID 16239184 DOI: 10.1016/S1474-4422(05)70223-4  0.333
2005 Shi J, Shaw CL, Du Plessis D, Richardson AM, Bailey KL, Julien C, Stopford C, Thompson J, Varma A, Craufurd D, Tian J, Pickering-Brown S, Neary D, Snowden JS, Mann DM. Histopathological changes underlying frontotemporal lobar degeneration with clinicopathological correlation. Acta Neuropathologica. 110: 501-12. PMID 16222525 DOI: 10.1007/S00401-005-1079-4  0.472
2005 Miyasaka T, Watanabe A, Saito Y, Murayama S, Mann DM, Yamazaki M, Ravid R, Morishima-Kawashima M, Nagashima K, Ihara Y. Visualization of newly deposited tau in neurofibrillary tangles and neuropil threads. Journal of Neuropathology and Experimental Neurology. 64: 665-74. PMID 16106214 DOI: 10.1097/01.Jnen.0000173890.79058.1D  0.403
2005 Pritchard A, Harris J, Pritchard CW, St Clair D, Lemmon H, Lambert JC, Chartier-Harlin MC, Hayes A, Thaker U, Iwatsubo T, Mann DM, Lendon C. Association study and meta-analysis of low-density lipoprotein receptor related protein in Alzheimer's disease. Neuroscience Letters. 382: 221-6. PMID 15925094 DOI: 10.1016/J.Neulet.2005.03.016  0.458
2005 Broe M, Shepherd CE, Mann DM, Milward EA, Gai WP, Thiel E, Halliday GM. Insoluble alpha-synuclein in Alzheimer's disease without Lewy body formation. Neurotoxicity Research. 7: 69-76. PMID 15639799 DOI: 10.1007/Bf03033777  0.361
2004 Hayes A, Green EK, Pritchard A, Harris JM, Zhang Y, Lambert JC, Chartier-Harlin MC, Pickering-Brown SM, Lendon CL, Mann DM. A polymorphic variation in the interleukin 1A gene increases brain microglial cell activity in Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 75: 1475-7. PMID 15377701 DOI: 10.1136/Jnnp.2003.030866  0.304
2004 Snowden JS, Neary D, Mann DM. Autopsy proven sporadic frontotemporal dementia due to microvacuolar-type histology, with onset at 21 years of age. Journal of Neurology, Neurosurgery, and Psychiatry. 75: 1337-9. PMID 15314128 DOI: 10.1136/Jnnp.2003.028498  0.433
2004 Pritchard A, St Clair D, Lemmon H, Mann DM, Lendon C. No association between polymorphisms in the lectin-like oxidised low density lipoprotein receptor (ORL1) gene on chromosome 12 and Alzheimer's disease in a UK cohort. Neuroscience Letters. 366: 126-9. PMID 15276231 DOI: 10.1016/J.Neulet.2004.05.023  0.422
2004 van Dijk R, Fischer DF, Sluijs JA, Sonnemans MA, Hobo B, Mercken L, Mann DM, Hol EM, van Leeuwen FW. Frame-shifted amyloid precursor protein found in Alzheimer's disease and Down's syndrome increases levels of secreted amyloid beta40. Journal of Neurochemistry. 90: 712-23. PMID 15255950 DOI: 10.1111/J.1471-4159.2004.02528.X  0.416
2004 Kowa H, Sakakura T, Matsuura Y, Wakabayashi T, Mann DM, Duff K, Tsuji S, Hashimoto T, Iwatsubo T. Mostly separate distributions of CLAC- versus Abeta40- or thioflavin S-reactivities in senile plaques reveal two distinct subpopulations of beta-amyloid deposits. The American Journal of Pathology. 165: 273-81. PMID 15215182 DOI: 10.1016/S0002-9440(10)63295-6  0.386
2004 Tian J, Shi J, Bailey K, Lendon CL, Pickering-Brown SM, Mann DM. Association between apolipoprotein E e4 allele and arteriosclerosis, cerebral amyloid angiopathy, and cerebral white matter damage in Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 75: 696-9. PMID 15090562 DOI: 10.1136/Jnnp.2003.012096  0.378
2004 Busby V, Goossens S, Nowotny P, Hamilton G, Smemo S, Harold D, Turic D, Jehu L, Myers A, Womick M, Woo D, Compton D, Doil LM, Tacey KM, Lau KF, ... ... Mann D, et al. Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease. Neuromolecular Medicine. 5: 133-46. PMID 15075440 DOI: 10.1385/Nmm:5:2:133  0.386
2004 Umeda Y, Taniguchi S, Arima K, Piao YS, Takahashi H, Iwatsubo T, Mann D, Hasegawa M. Alterations in human tau transcripts correlate with those of neurofilament in sporadic tauopathies. Neuroscience Letters. 359: 151-4. PMID 15050686 DOI: 10.1016/J.Neulet.2004.01.060  0.382
2004 Pickering-Brown SM, Baker M, Nonaka T, Ikeda K, Sharma S, Mackenzie J, Simpson SA, Moore JW, Snowden JS, de Silva R, Revesz T, Hasegawa M, Hutton M, Mann DM. Frontotemporal dementia with Pick-type histology associated with Q336R mutation in the tau gene. Brain : a Journal of Neurology. 127: 1415-26. PMID 15047590 DOI: 10.1093/Brain/Awh147  0.447
2004 Cook LJ, Ho LW, Taylor AE, Brayne C, Evans JG, Xuereb J, Cairns NJ, Pritchard A, Lemmon H, Mann D, St Clair D, Turic D, Hollingworth P, Moore PJ, Jehu L, et al. Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease. Neuroscience Letters. 358: 142-6. PMID 15026168 DOI: 10.1016/J.Neulet.2004.01.016  0.42
2004 Lambert JC, Mann D, Harris J, Araria-Goumidi L, Chartier-Harlin MC, Cottel D, Iwatsubo T, Amouyel P, Lendon C. Association study of Notch 4 polymorphisms with Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 75: 377-81. PMID 14966150  0.32
2004 Pickering-Brown S, Baker M, Bird T, Trojanowski J, Lee V, Morris H, Rossor M, Janssen JC, Neary D, Craufurd D, Richardson A, Snowden J, Hardy J, Mann D, Hutton M. Evidence of a founder effect in families with frontotemporal dementia that harbor the tau +16 splice mutation. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 125: 79-82. PMID 14755449 DOI: 10.1002/Ajmg.B.20083  0.377
2004 Tian J, Shi J, Bailey K, Mann DM. Relationships between arteriosclerosis, cerebral amyloid angiopathy and myelin loss from cerebral cortical white matter in Alzheimer's disease. Neuropathology and Applied Neurobiology. 30: 46-56. PMID 14720176 DOI: 10.1046/J.0305-1846.2003.00510.X  0.374
2004 Taniguchi S, McDonagh AM, Pickering-Brown SM, Umeda Y, Iwatsubo T, Hasegawa M, Mann DM. The neuropathology of frontotemporal lobar degeneration with respect to the cytological and biochemical characteristics of tau protein. Neuropathology and Applied Neurobiology. 30: 1-18. PMID 14720172 DOI: 10.1046/J.0305-1846.2003.00481.X  0.447
2004 Tian J, Shi J, Bailey K, Harris JM, Pritchard A, Lambert JC, Chartier-Harlin MC, Pickering-Brown SM, Lendon CL, Mann DM. A polymorphism in the angiotensin 1-converting enzyme gene is associated with damage to cerebral cortical white matter in Alzheimer's disease. Neuroscience Letters. 354: 103-6. PMID 14698449 DOI: 10.1016/J.Neulet.2003.09.072  0.334
2004 Lambert J, Mann D, Richard F, Tian J, Shi J, Thaker U, Merrot S, Harris J, Chartier-Harlin M, Sazdovitch V, Mohr M, Frigard B, Hauw J, Lendon C, Iwatsubo T, et al. P4-083 Is there a relation between APOE expression and amyloid depositions in the brain of Alzheimer's disease cases? Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81641-5  0.324
2003 Tian J, Shi J, Bailey K, Mann DM. Negative association between amyloid plaques and cerebral amyloid angiopathy in Alzheimer's disease. Neuroscience Letters. 352: 137-40. PMID 14625042 DOI: 10.1016/j.neulet.2003.08.048  0.333
2003 McCarron MO, Stewart J, McCarron P, Love S, Vinters HV, Ironside JW, Mann DM, Graham DI, Nicoll JA. Association between interleukin-1A polymorphism and cerebral amyloid angiopathy-related hemorrhage. Stroke; a Journal of Cerebral Circulation. 34: e193-5. PMID 12947160 DOI: 10.1161/01.Str.0000089294.85447.1E  0.37
2003 Lambert JC, Luedecking-Zimmer E, Merrot S, Hayes A, Thaker U, Desai P, Houzet A, Hermant X, Cottel D, Pritchard A, Iwatsubo T, Pasquier F, Frigard B, Conneally PM, Chartier-Harlin MC, ... ... Mann D, et al. Association of 3'-UTR polymorphisms of the oxidised LDL receptor 1 (OLR1) gene with Alzheimer's disease. Journal of Medical Genetics. 40: 424-30. PMID 12807963 DOI: 10.1136/Jmg.40.6.424  0.303
2003 Hughes A, Mann D, Pickering-Brown S. Tau haplotype frequency in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Experimental Neurology. 181: 12-16. PMID 12710929 DOI: 10.1016/S0014-4886(03)00024-4  0.399
2003 Zhukareva V, Sundarraj S, Mann D, Sjogren M, Blenow K, Clark CM, McKeel DW, Goate A, Lippa CF, Vonsattel JP, Growdon JH, Trojanowski JQ, Lee VM. Selective reduction of soluble tau proteins in sporadic and familial frontotemporal dementias: an international follow-up study. Acta Neuropathologica. 105: 469-76. PMID 12677447 DOI: 10.1007/S00401-002-0668-8  0.442
2003 Thaker U, McDonagh AM, Iwatsubo T, Lendon CL, Pickering-Brown SM, Mann DM. Tau load is associated with apolipoprotein E genotype and the amount of amyloid beta protein, Abeta40, in sporadic and familial Alzheimer's disease. Neuropathology and Applied Neurobiology. 29: 35-44. PMID 12581338 DOI: 10.1046/J.1365-2990.2003.00425.X  0.467
2003 Huckvale C, Richardson AM, Mann DM, Pickering-Brown SM. Debrisoquine hydroxylase gene polymorphism (CYP2D6*4) in dementia with Lewy bodies. Journal of Neurology, Neurosurgery, and Psychiatry. 74: 135-6. PMID 12486288 DOI: 10.1136/Jnnp.74.1.135  0.462
2002 Snowden JS, Mann DM, Neary D. Distinct neuropsychological characteristics in Creutzfeldt-Jakob disease. Journal of Neurology, Neurosurgery, and Psychiatry. 73: 686-94. PMID 12438471 DOI: 10.1136/Jnnp.73.6.686  0.356
2002 Hayes A, Thaker U, Iwatsubo T, Pickering-Brown SM, Mann DM. Pathological relationships between microglial cell activity and tau and amyloid beta protein in patients with Alzheimer's disease. Neuroscience Letters. 331: 171-4. PMID 12383924 DOI: 10.1016/S0304-3940(02)00888-1  0.308
2002 Lendon CL, Thaker U, Harris JM, McDonagh AM, Lambert JC, Chartier-Harlin MC, Iwatsubo T, Pickering-Brown SM, Mann DM. The angiotensin 1-converting enzyme insertion (I)/deletion (D) polymorphism does not influence the extent of amyloid or tau pathology in patients with sporadic Alzheimer's disease. Neuroscience Letters. 328: 314-8. PMID 12147333 DOI: 10.1016/S0304-3940(02)00553-0  0.319
2002 Zhukareva V, Mann D, Pickering-Brown S, Uryu K, Shuck T, Shah K, Grossman M, Miller BL, Hulette CM, Feinstein SC, Trojanowski JQ, Lee VM. Sporadic Pick's disease: a tauopathy characterized by a spectrum of pathological tau isoforms in gray and white matter. Annals of Neurology. 51: 730-9. PMID 12112079 DOI: 10.1002/Ana.10222  0.425
2002 Araria-Goumidi L, Lambert JC, Mann DM, Lendon C, Frigard B, Iwatsubo T, Cottel D, Amouyel P, Chartier-Harlin MC. Association study of three polymorphisms of TGF-beta1 gene with Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 73: 62-4. PMID 12082048 DOI: 10.1136/Jnnp.73.1.62  0.301
2002 Green EK, Thaker U, McDonagh AM, Iwatsubo T, Lambert JC, Chartier-Harlin MC, Harris JM, Pickering-Brown SM, Lendon CL, Mann DM. A polymorphism within intron 11 of the tau gene is not increased in frequency in patients with sporadic Alzheimer's disease, nor does it influence the extent of tau pathology in the brain. Neuroscience Letters. 324: 113-6. PMID 11988340 DOI: 10.1016/S0304-3940(02)00190-8  0.356
2002 Hashimoto T, Wakabayashi T, Watanabe A, Kowa H, Hosoda R, Nakamura A, Kanazawa I, Arai T, Takio K, Mann DM, Iwatsubo T. CLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXV. The Embo Journal. 21: 1524-34. PMID 11927537 DOI: 10.1093/Emboj/21.7.1524  0.397
2002 Pickering-Brown SM, Richardson AM, Snowden JS, McDonagh AM, Burns A, Braude W, Baker M, Liu WK, Yen SH, Hardy J, Hutton M, Davies Y, Allsop D, Craufurd D, Neary D, ... Mann DM, et al. Inherited frontotemporal dementia in nine British families associated with intronic mutations in the tau gene. Brain : a Journal of Neurology. 125: 732-51. PMID 11912108 DOI: 10.1093/Brain/Awf069  0.447
2001 Lambert JC, Mann D, Goumidi L, Harris J, Amouyel P, Iwatsubo T, Lendon C, Chartier-Harlin MC. Effect of the APOE promoter polymorphisms on cerebral amyloid peptide deposition in Alzheimer's disease. Lancet. 357: 608-9. PMID 11558492 DOI: 10.1016/S0140-6736(00)04063-0  0.358
2001 Houlden H, Baker M, Morris HR, MacDonald N, Pickering-Brown S, Adamson J, Lees AJ, Rossor MN, Quinn NP, Kertesz A, Khan MN, Hardy J, Lantos PL, St George-Hyslop P, Munoz DG, ... Mann D, et al. Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype. Neurology. 56: 1702-6. PMID 11425937 DOI: 10.1212/Wnl.56.12.1702  0.404
2001 Mann DM, Pickering-Brown SM, Takeuchi A, Iwatsubo T. Amyloid angiopathy and variability in amyloid beta deposition is determined by mutation position in presenilin-1-linked Alzheimer's disease. The American Journal of Pathology. 158: 2165-75. PMID 11395394 DOI: 10.1016/S0002-9440(10)64688-3  0.438
2001 Lambert JC, Mann DM, Harris JM, Chartier-Harlin MC, Cumming A, Coates J, Lemmon H, StClair D, Iwatsubo T, Lendon C. The -48 C/T polymorphism in the presenilin 1 promoter is associated with an increased risk of developing Alzheimer's disease and an increased Abeta load in brain. Journal of Medical Genetics. 38: 353-5. PMID 11389157 DOI: 10.1136/Jmg.38.6.353  0.432
2001 Mann DM. Anosmia in dementia is associated with Lewy bodies rather than Alzheimer's pathology. Journal of Neurology, Neurosurgery, and Psychiatry. 70: 720-1. PMID 11385001  0.313
2001 Mann DM, McDonagh AM, Pickering-Brown SM, Kowa H, Iwatsubo T. Amyloid beta protein deposition in patients with frontotemporal lobar degeneration: relationship to age and apolipoprotein E genotype. Neuroscience Letters. 304: 161-4. PMID 11343827 DOI: 10.1016/S0304-3940(01)01785-2  0.374
2001 Russ C, Lovestone S, Baker M, Pickering-Brown SM, Andersen PM, Furlong R, Mann D, Powell JF. The extended haplotype of the microtubule associated protein tau gene is not associated with Pick's disease. Neuroscience Letters. 299: 156-8. PMID 11166961 DOI: 10.1016/S0304-3940(00)01785-7  0.459
2000 Pickering-Brown S, Baker M, Yen SH, Liu WK, Hasegawa M, Cairns N, Lantos PL, Rossor M, Iwatsubo T, Davies Y, Allsop D, Furlong R, Owen F, Hardy J, Mann D, et al. Pick's disease is associated with mutations in the tau gene. Annals of Neurology. 48: 859-67. PMID 11117542 DOI: 10.1002/1531-8249(200012)48:6<859::Aid-Ana6>3.0.Co;2-1  0.323
2000 Neary D, Snowden JS, Mann DM. Cognitive change in motor neurone disease/amyotrophic lateral sclerosis (MND/ALS). Journal of the Neurological Sciences. 180: 15-20. PMID 11090859 DOI: 10.1016/S0022-510X(00)00425-1  0.34
2000 Lambert JC, Mann D, Goumidi L, Harris J, Pasquier F, Frigard B, Cottel D, Lendon C, Iwatsubo T, Amouyel P, Chartier-Harlin MC. A FE65 polymorphism associated with risk of developing sporadic late-onset alzheimer's disease but not with Abeta loading in brains. Neuroscience Letters. 293: 29-32. PMID 11065130 DOI: 10.1016/S0304-3940(00)01477-4  0.332
2000 Lambert JC, Goumidi L, Vrièze FW, Frigard B, Harris JM, Cummings A, Coates J, Pasquier F, Cottel D, Gaillac M, St Clair D, Mann DM, Hardy J, Lendon CL, Amouyel P, et al. The transcriptional factor LBP-1c/CP2/LSF gene on chromosome 12 is a genetic determinant of Alzheimer's disease. Human Molecular Genetics. 9: 2275-80. PMID 11001930 DOI: 10.1093/Oxfordjournals.Hmg.A018918  0.402
2000 Takeuchi A, Irizarry MC, Duff K, Saido TC, Hsiao Ashe K, Hasegawa M, Mann DM, Hyman BT, Iwatsubo T. Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss. The American Journal of Pathology. 157: 331-9. PMID 10880403 DOI: 10.1016/S0002-9440(10)64544-0  0.357
2000 Pickering-Brown SM, Owen F, Isaacs A, Snowden J, Varma A, Neary D, Furlong R, Daniel SE, Cairns NJ, Mann DM. Apolipoprotein E epsilon4 allele has no effect on age at onset or duration of disease in cases of frontotemporal dementia with pick- or microvacuolar-type histology. Experimental Neurology. 163: 452-6. PMID 10833320 DOI: 10.1006/Exnr.2000.7387  0.466
2000 McCarron MO, Nicoll JA, Stewart J, Cole GM, Yang F, Ironside JW, Mann DM, Love S, Graham DI. Amyloid beta-protein length and cerebral amyloid angiopathy-related haemorrhage. Neuroreport. 11: 937-40. PMID 10790859 DOI: 10.1097/00001756-200004070-00008  0.304
1999 Lippa CF, Ozawa K, Mann DM, Ishii K, Smith TW, Arawaka S, Mori H. Deposition of beta-amyloid subtypes 40 and 42 differentiates dementia with Lewy bodies from Alzheimer disease. Archives of Neurology. 56: 1111-8. PMID 10488812 DOI: 10.1001/Archneur.56.9.1111  0.474
1999 Houlden H, Baker M, Adamson J, Grover A, Waring S, Dickson D, Lynch T, Boeve B, Petersen RC, Pickering-Brown S, Owen F, Neary D, Craufurd D, Snowden J, Mann D, et al. Frequency of tau mutations in three series of non-Alzheimer's degenerative dementia. Annals of Neurology. 46: 243-8. PMID 10443890 DOI: 10.1002/1531-8249(199908)46:2<243::Aid-Ana14>3.0.Co;2-L  0.309
1999 Romero I, Jørgensen P, Bolwig G, Fraser PE, Rogaeva E, Mann D, Havsager AM, Jørgensen AL. A presenilin-1 Thr116Asn substitution in a family with early-onset Alzheimer's disease. Neuroreport. 10: 2255-60. PMID 10439444 DOI: 10.1097/00001756-199908020-00006  0.453
1999 Wu C, Singh SK, Dias P, Kumar S, Mann DM. Activated astrocytes display increased 5-HT2a receptor expression in pathological states. Experimental Neurology. 158: 529-33. PMID 10415157 DOI: 10.1006/Exnr.1999.7105  0.353
1999 McCarron MO, Nicoll JA, Stewart J, Ironside JW, Mann DM, Love S, Graham DI, Dewar D. The apolipoprotein E epsilon2 allele and the pathological features in cerebral amyloid angiopathy-related hemorrhage. Journal of Neuropathology and Experimental Neurology. 58: 711-8. PMID 10411341 DOI: 10.1097/00005072-199907000-00005  0.425
1999 Houlden H, Rizzu P, Stevens M, de Knijff P, van Duijn CM, van Swieten JC, Heutink P, Perez-Tur J, Thomas V, Baker M, Morris H, Rossor M, Jannsen JC, Petersen RC, Dodd P, ... ... Mann D, et al. Apolipoprotein E genotype does not affect the age of onset of dementia in families with defined tau mutations. Neuroscience Letters. 260: 193-5. PMID 10076900 DOI: 10.1016/S0304-3940(98)00931-8  0.461
1999 Varma AR, Snowden JS, Lloyd JJ, Talbot PR, Mann DM, Neary D. Evaluation of the NINCDS-ADRDA criteria in the differentiation of Alzheimer's disease and frontotemporal dementia. Journal of Neurology, Neurosurgery, and Psychiatry. 66: 184-8. PMID 10071097 DOI: 10.1136/Jnnp.66.2.184  0.45
1998 Hosoda R, Saido TC, Otvos L, Arai T, Mann DM, Lee VM, Trojanowski JQ, Iwatsubo T. Quantification of modified amyloid beta peptides in Alzheimer disease and Down syndrome brains. Journal of Neuropathology and Experimental Neurology. 57: 1089-95. PMID 9825946 DOI: 10.1097/00005072-199811000-00012  0.306
1998 Lippa CF, Fujiwara H, Mann DM, Giasson B, Baba M, Schmidt ML, Nee LE, O'Connell B, Pollen DA, St George-Hyslop P, Ghetti B, Nochlin D, Bird TD, Cairns NJ, Lee VM, et al. Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. The American Journal of Pathology. 153: 1365-70. PMID 9811326 DOI: 10.1016/S0002-9440(10)65722-7  0.372
1998 Sieradzan KA, Mann DM. On the pathological progression of Huntington's disease. Annals of Neurology. 44: 148-9. PMID 9667607 DOI: 10.1002/Ana.410440127  0.379
1998 Hutton M, Lendon CL, Rizzu P, Baker M, Froelich S, Houlden H, Pickering-Brown S, Chakraverty S, Isaacs A, Grover A, Hackett J, Adamson J, Lincoln S, Dickson D, Davies P, ... ... Mann D, et al. Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17. Nature. 393: 702-5. PMID 9641683 DOI: 10.1038/31508  0.414
1998 Burlinson S, Burns A, Mann D, Pickering-Brown S, Owen F. Effect of apolipoprotein E status on clinical features of dementia. International Journal of Geriatric Psychiatry. 13: 177-185. PMID 9565840 DOI: 10.1002/(Sici)1099-1166(199803)13:3<177::Aid-Gps758>3.0.Co;2-M  0.427
1997 Galvin JE, Lee VM, Baba M, Mann DM, Dickson DW, Yamaguchi H, Schmidt ML, Iwatsubo T, Trojanowski JQ. Monoclonal antibodies to purified cortical Lewy bodies recognize the mid-size neurofilament subunit. Annals of Neurology. 42: 595-603. PMID 9382471 DOI: 10.1002/Ana.410420410  0.426
1997 Mann DM. Molecular biology's impact on our understanding of aging. Bmj (Clinical Research Ed.). 315: 1078-81. PMID 9366741 DOI: 10.1136/Bmj.315.7115.1078  0.346
1997 Sieradzan K, Mann DM, Dodge A. Clinical presentation and patterns of regional cerebral atrophy related to the length of trinucleotide repeat expansion in patients with adult onset Huntington's disease. Neuroscience Letters. 225: 45-8. PMID 9143014 DOI: 10.1016/S0304-3940(97)00182-1  0.38
1997 Mann DM, Iwatsubo T, Nochlin D, Sumi SM, Levy-Lahad E, Bird TD. Amyloid (Abeta) deposition in chromosome 1-linked Alzheimer's disease: the Volga German families. Annals of Neurology. 41: 52-7. PMID 9005865 DOI: 10.1002/Ana.410410110  0.315
1996 Mann DM. Pyramidal nerve cell loss in Alzheimer's disease. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 5: 423-7. PMID 9117557 DOI: 10.1006/Neur.1996.0057  0.377
1996 Barton AJ, Crook BW, Karran EH, Brown F, Dewar D, Mann DM, Pearson RC, Graham DI, Hardy J, Hutton M, Duff K, Goate AM, Clark RF, Roberts GW. Alteration in brain presenilin 1 mRNA expression in early onset familial Alzheimer's disease. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 5: 213-8. PMID 8910899 DOI: 10.1006/Neur.1996.0029  0.352
1996 Cooper PN, Jackson M, Lennox G, Lowe L, Mann DM. Brain-stem inclusions in motor neuron disease-type dementia. Archives of Neurology. 53: 836. PMID 8815844 DOI: 10.1001/Archneur.1996.00550090018002  0.359
1996 Mann DM, Iwatsubo T, Snowden JS. Atypical amyloid (A beta) deposition in the cerebellum in Alzheimer's disease: an immunohistochemical study using end-specific A beta monoclonal antibodies. Acta Neuropathologica. 91: 647-53. PMID 8781665 DOI: 10.1007/S004010050479  0.311
1996 Mann DM, Iwatsubo T, Cairns NJ, Lantos PL, Nochlin D, Sumi SM, Bird TD, Poorkaj P, Hardy J, Hutton M, Prihar G, Crook R, Rossor MN, Haltia M. Amyloid beta protein (Abeta) deposition in chromosome 14-linked Alzheimer's disease: predominance of Abeta42(43). Annals of Neurology. 40: 149-56. PMID 8773595 DOI: 10.1002/Ana.410400205  0.301
1996 Siddons MA, Pickering-Brown SM, Mann DM, Owen F, Cooper PN. Debrisoquine hydroxylase gene polymorphism frequencies in patients with amyotrophic lateral sclerosis. Neuroscience Letters. 208: 65-8. PMID 8731176 DOI: 10.1016/0304-3940(96)12549-0  0.354
1996 Royston MC, Mann D, Pickering-Brown S, Owen F, Perry R, Ragbavan R, Khin-Nu C, Tyner S, Day K, Crook R, Hardy J, Roberts GW. ApoE2 allele, Down's syndrome, and dementia Annals of the New York Academy of Sciences. 777: 255-259. PMID 8624094 DOI: 10.1111/J.1749-6632.1996.Tb34428.X  0.463
1996 Teller JK, Russo C, DeBusk LM, Angelini G, Zaccheo D, Dagna-Bricarelli F, Scartezzini P, Bertolini S, Mann DM, Tabaton M, Gambetti P. Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome. Nature Medicine. 2: 93-5. PMID 8564851 DOI: 10.1038/Nm0196-93  0.354
1995 Pickering-Brown SM, Mann DM, Owen F, Ironside JW, de Silva R, Roberts DA, Balderson DJ, Cooper PN. Allelic variations in apolipoprotein E and prion protein genotype related to plaque formation and age of onset in sporadic Creutzfeldt-Jakob disease. Neuroscience Letters. 187: 127-9. PMID 7783958 DOI: 10.1016/0304-3940(95)11353-3  0.403
1995 Hyman BT, West HL, Rebeck GW, Lai F, Mann DM. Neuropathological changes in Down's syndrome hippocampal formation. Effect of age and apolipoprotein E genotype. Archives of Neurology. 52: 373-8. PMID 7710373 DOI: 10.1001/Archneur.1995.00540280059019  0.44
1995 Pickering-Brown SM, Siddons M, Mann DM, Owen F, Neary D, Snowden JS. Apolipoprotein E allelic frequencies in patients with lobar atrophy. Neuroscience Letters. 188: 205-7. PMID 7609910 DOI: 10.1016/0304-3940(95)11425-V  0.443
1995 Cooper PN, Jackson M, Lennox G, Lowe J, Mann DM. Tau, ubiquitin, and alpha B-crystallin immunohistochemistry define the principal causes of degenerative frontotemporal dementia. Archives of Neurology. 52: 1011-5. PMID 7575218 DOI: 10.1001/Archneur.1995.00540340103019  0.465
1995 Mann DM, Pickering-Brown SM, Siddons MA, Iwatsubo T, Ihara Y, Asami-Odaka A, Suzuki N. The extent of amyloid deposition in brain in patients with Down's syndrome does not depend upon the apolipoprotein E genotype. Neuroscience Letters. 196: 105-8. PMID 7501233 DOI: 10.1016/0304-3940(95)11860-Y  0.346
1994 Webster MT, Francis PT, Procter AW, Stratmann GC, Doshi R, Mann DM, Bowen DM. Postmortem brains reveal similar but not identical amyloid precursor protein-like immunoreactivity in Alzheimer compared with other dementias. Brain Research. 644: 347-51. PMID 8050048 DOI: 10.1016/0006-8993(94)91702-7  0.358
1994 Mann DM. Pathological correlates of dementia in Alzheimer's disease. Neurobiology of Aging. 15: 357-60; discussion 3. PMID 7936062 DOI: 10.1016/0197-4580(94)90033-7  0.448
1994 Royston MC, Mann D, Pickering-Brown S, Owen F, Perry R, Raghavan R, Khin-Nu C, Tyrer S, Day K, Crook R. Apolipoprotein E epsilon 2 allele promotes longevity and protects patients with Down's syndrome from dementia. Neuroreport. 5: 2583-5. PMID 7696609 DOI: 10.1097/00001756-199412000-00044  0.429
1994 Mann DM. Alzheimer's disease: progress in pathological and aetiological aspects Reviews in Clinical Gerontology. 4: 43-60. DOI: 10.1017/S0959259800002252  0.331
1993 Mann DM, Oliver R, Snowden JS. The topographic distribution of brain atrophy in Huntington's disease and progressive supranuclear palsy. Acta Neuropathologica. 85: 553-9. PMID 8493863 DOI: 10.1007/Bf00230496  0.331
1993 Neary D, Snowden JS, Mann DM. The clinical pathological correlates of lobar atrophy. Dementia (Basel, Switzerland). 4: 154-9. PMID 8401784 DOI: 10.1159/000107315  0.375
1993 Clinton J, Mann DM, Roberts GW. Frontal lobe dementia is not a variant of prion disease. Neuroscience Letters. 164: 1-4. PMID 8152581 DOI: 10.1016/0304-3940(93)90842-9  0.437
1992 Mann DM, Jones D, Snowden JS, Neary D, Hardy J. Pathological changes in the brain of a patient with familial Alzheimer's disease having a missense mutation at codon 717 in the amyloid precursor protein gene. Neuroscience Letters. 137: 225-8. PMID 1584464 DOI: 10.1016/0304-3940(92)90409-Z  0.367
1992 Hanger DP, Mann DM, Neary D, Anderton BH. Tau pathology in a case of familial Alzheimer's disease with a valine to glycine mutation at position 717 in the amyloid precursor protein. Neuroscience Letters. 145: 178-80. PMID 1465214 DOI: 10.1016/0304-3940(92)90016-Z  0.491
1992 German DC, Manaye KF, White CL, Woodward DJ, McIntire DD, Smith WK, Kalaria RN, Mann DM. Disease-specific patterns of locus coeruleus cell loss. Annals of Neurology. 32: 667-76. PMID 1449247 DOI: 10.1002/Ana.410320510  0.387
1992 Hanger DP, Mann DM, Neary D, Anderton BH. Molecular pathology of Alzheimer's disease in sporadic and familial Alzheimer's disease with mutations in the amyloid precursor protein. Biochemical Society Transactions. 20: 642-5. PMID 1426605 DOI: 10.1042/Bst0200642  0.453
1991 Mann DM. Is the pattern of nerve cell loss in aging and Alzheimer's disease a real, or only an apparent, selectivity? Neurobiology of Aging. 12: 340-3; discussion 35. PMID 1961366 DOI: 10.1016/0197-4580(91)90015-C  0.447
1991 Guy SP, Jones D, Mann DM, Itzhaki RF. Human neuroblastoma cells treated with aluminium express an epitope associated with Alzheimer's disease neurofibrillary tangles. Neuroscience Letters. 121: 166-8. PMID 1708474 DOI: 10.1016/0304-3940(91)90676-K  0.398
1990 Gibb WR, Mann DM, Mountjoy CQ, Lees AJ. A pathological study of the association between Lewy body disease and Alzheimer's disease. Advances in Neurology. 53: 55-9. PMID 2173375  0.31
1990 Flament S, Delacourte A, Mann DM. Phosphorylation of Tau proteins: a major event during the process of neurofibrillary degeneration. A comparative study between Alzheimer's disease and Down's syndrome. Brain Research. 516: 15-9. PMID 2142011 DOI: 10.1016/0006-8993(90)90891-E  0.367
1989 Mann DM. Calcification of the basal ganglia in Down's syndrome and Alzheimer's disease. Acta Neuropathologica. 76: 595-8. PMID 2974228 DOI: 10.1007/BF00689598  0.303
1989 Mann DM. Neuropathology of Alzheimer's disease: towards an understanding of the pathogenesis. Biochemical Society Transactions. 17: 73-5. PMID 2714518 DOI: 10.1042/Bst0170073  0.428
1989 Gibb WR, Mountjoy CQ, Mann DM, Lees AJ. A pathological study of the association between Lewy body disease and Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 52: 701-8. PMID 2545826  0.31
1989 Mann DM. Cerebral amyloidosis, ageing and Alzheimer's disease; a contribution from studies on Down's syndrome. Neurobiology of Aging. 10: 397-9; discussion 41. PMID 2530459 DOI: 10.1016/0197-4580(89)90073-0  0.409
1989 Mann DM, Esiri MM. The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome. Journal of the Neurological Sciences. 89: 169-79. PMID 2522541 DOI: 10.1016/0022-510X(89)90019-1  0.367
1988 Mann DM, Bonshek RE, Marcyniuk B, Stoddart RW, Torgerson E. Saccharides of senile plaques and neurofibrillary tangles in Alzheimer's disease. Neuroscience Letters. 85: 277-82. PMID 3374842 DOI: 10.1016/0304-3940(88)90365-5  0.317
1988 Mann DM, Tucker CM, Yates PO. Alzheimer's disease: an olfactory connection? Mechanisms of Ageing and Development. 42: 1-15. PMID 2964546 DOI: 10.1016/0047-6374(88)90058-9  0.39
1987 Mann DM, Tucker CM, Yates PO. The topographic distribution of senile plaques and neurofibrillary tangles in the brains of non-demented persons of different ages. Neuropathology and Applied Neurobiology. 13: 123-39. PMID 3614541 DOI: 10.1111/J.1365-2990.1987.Tb00176.X  0.315
1986 Neary D, Snowden JS, Bowen DM, Sims NR, Mann DM, Benton JS, Northen B, Yates PO, Davison AN. Neuropsychological syndromes in presenile dementia due to cerebral atrophy. Journal of Neurology, Neurosurgery, and Psychiatry. 49: 163-74. PMID 2419511 DOI: 10.1136/jnnp.49.2.163  0.322
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