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Lars Lannfelt, MD PhD - Publications

Affiliations: 
Molecular Geriatrics Uppsala University, Uppsala, Uppsala län, Sweden 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=108
Website:
http://www.pubcare.uu.se/molekyl/index_en.shtml

401 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Hampel H, Hardy J, Blennow K, Chen C, Perry G, Kim SH, Villemagne VL, Aisen P, Vendruscolo M, Iwatsubo T, Masters CL, Cho M, Lannfelt L, Cummings JL, Vergallo A. The Amyloid-β Pathway in Alzheimer's Disease. Molecular Psychiatry. PMID 34456336 DOI: 10.1038/s41380-021-01249-0  1
2021 Pagnon de la Vega M, Giedraitis V, Michno W, Kilander L, Güner G, Zielinski M, Löwenmark M, Brundin R, Danfors T, Söderberg L, Alafuzoff I, Nilsson LNG, Erlandsson A, Willbold D, Müller SA, ... ... Lannfelt L, et al. The deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation. Science Translational Medicine. 13. PMID 34380771 DOI: 10.1126/scitranslmed.abc6184  1
2021 Johannesson M, Sahlin C, Söderberg L, Basun H, Fälting J, Möller C, Zachrisson O, Sunnemark D, Svensson A, Odergren T, Lannfelt L. Elevated soluble amyloid beta protofibrils in Down syndrome and Alzheimer's disease. Molecular and Cellular Neurosciences. 114: 103641. PMID 34091073 DOI: 10.1016/j.mcn.2021.103641  1
2021 Zhang X, O'Callaghan P, Li H, Tan Y, Zhang G, Barash U, Wang X, Lannfelt L, Vlodavsky I, Lindahl U, Li JP. Heparanase overexpression impedes perivascular clearance of amyloid-β from murine brain: relevance to Alzheimer's disease. Acta Neuropathologica Communications. 9: 84. PMID 33971986 DOI: 10.1186/s40478-021-01182-x  1
2021 Swanson CJ, Zhang Y, Dhadda S, Wang J, Kaplow J, Lai RYK, Lannfelt L, Bradley H, Rabe M, Koyama A, Reyderman L, Berry DA, Berry S, Gordon R, Kramer LD, et al. A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Aβ protofibril antibody. Alzheimer's Research & Therapy. 13: 80. PMID 33865446 DOI: 10.1186/s13195-021-00813-8  1
2021 Gkanatsiou E, Sahlin C, Portelius E, Johannesson M, Söderberg L, Fälting J, Basun H, Möller C, Odergren T, Zetterberg H, Blennow K, Lannfelt L, Brinkmalm G. Characterization of monomeric and soluble aggregated Aβ in Down's syndrome and Alzheimer's disease brains. Neuroscience Letters. 754: 135894. PMID 33848613 DOI: 10.1016/j.neulet.2021.135894  1
2021 Surendran P, Feofanova EV, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, Chen L, Mifsud B, Yao C, Kraja AT, Cartwright JH, Hellwege JN, Giri A, Tragante V, Thorleifsson G, ... ... Lannfelt L, et al. Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nature Genetics. PMID 33727701 DOI: 10.1038/s41588-021-00832-z  1
2020 Syvänen S, Fang XT, Faresjö R, Rokka J, Lannfelt L, Olberg DE, Eriksson J, Sehlin D. Fluorine-18-Labeled Antibody Ligands for PET Imaging of Amyloid-β in Brain. Acs Chemical Neuroscience. PMID 33236886 DOI: 10.1021/acschemneuro.0c00652  1
2020 Surendran P, Feofanova EV, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, Chen L, Mifsud B, Yao C, Kraja AT, Cartwright JH, Hellwege JN, Giri A, Tragante V, Thorleifsson G, ... ... Lannfelt L, et al. Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nature Genetics. PMID 33230300 DOI: 10.1038/s41588-020-00713-x  1
2020 Bogdanovic N, Hansson O, Zetterberg H, Basun H, Ingelsson M, Lannfelt L, Blennow K. [Alzheimer's disease - the most common cause of dementia]. Lakartidningen. 117. PMID 32154904  1
2019 Danielsson M, Halvardson J, Davies H, Torabi Moghadam B, Mattisson J, Rychlicka-Buniowska E, Jaszczyński J, Heintz J, Lannfelt L, Giedraitis V, Ingelsson M, Dumanski JP, Forsberg LA. Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals. European Journal of Human Genetics : Ejhg. PMID 31654039 DOI: 10.1038/s41431-019-0533-z  1
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Lannfelt L, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7  1
2019 Almkvist O, Rodriguez-Vieitez E, Thordardottir S, Nordberg A, Viitanen M, Lannfelt L, Graff C. Longitudinal cognitive decline in autosomal-dominant Alzheimer's disease varies with mutations in APP and PSEN1 genes. Neurobiology of Aging. 82: 40-47. PMID 31386938 DOI: 10.1016/J.Neurobiolaging.2019.06.010  1
2019 Aoyagi A, Condello C, Stöhr J, Yue W, Rivera BM, Lee JC, Woerman AL, Halliday G, van Duinen S, Ingelsson M, Lannfelt L, Graff C, Bird TD, Keene CD, Seeley WW, et al. Aβ and tau prion-like activities decline with longevity in the Alzheimer's disease human brain. Science Translational Medicine. 11. PMID 31043574 DOI: 10.1126/Scitranslmed.Aat8462  1
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Lannfelt L, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  1
2019 Khoonsari PE, Shevchenko G, Herman S, Remnestål J, Giedraitis V, Brundin R, Gunnarsson MD, Kilander L, Zetterberg H, Nilsson P, Lannfelt L, Ingelsson M, Kultima K. Improved Differential Diagnosis of Alzheimer's Disease by Integrating ELISA and Mass Spectrometry-Based Cerebrospinal Fluid Biomarkers. Journal of Alzheimer's Disease : Jad. PMID 30614806 DOI: 10.3233/Jad-180855  1
2018 Forsberg LA, Halvardson J, Rychlicka-Buniowska E, Danielsson M, Moghadam BT, Mattisson J, Rasi C, Davies H, Lind L, Giedraitis V, Lannfelt L, Kilander L, Ingelsson M, Dumanski JP. Mosaic loss of chromosome Y in leukocytes matters. Nature Genetics. PMID 30374072 DOI: 10.1038/s41588-018-0267-9  1
2018 Sardar Sinha M, Ansell-Schultz A, Civitelli L, Hildesjö C, Larsson M, Lannfelt L, Ingelsson M, Hallbeck M. Alzheimer's disease pathology propagation by exosomes containing toxic amyloid-beta oligomers. Acta Neuropathologica. 136: 41-56. PMID 29934873 DOI: 10.1007/s00401-018-1868-1  1
2018 György B, Lööv C, Zaborowski MP, Takeda S, Kleinstiver BP, Commins C, Kastanenka K, Mu D, Volak A, Giedraitis V, Lannfelt L, Maguire CA, Joung JK, Hyman BT, Breakefield XO, et al. CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease. Molecular Therapy. Nucleic Acids. 11: 429-440. PMID 29858078 DOI: 10.1016/J.Omtn.2018.03.007  1
2018 Meier SR, Syvänen S, Hultqvist G, Fang XT, Roshanbin S, Lannfelt L, Neumann U, Sehlin D. Antibody-based in vivo PET imaging detects amyloid-β reduction in Alzheimer transgenic mice after BACE-1 inhibition. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 29853653 DOI: 10.2967/jnumed.118.213140  1
2018 Syvänen S, Hultqvist G, Gustavsson T, Gumucio A, Laudon H, Söderberg L, Ingelsson M, Lannfelt L, Sehlin D. Efficient clearance of Aβ protofibrils in AβPP-transgenic mice treated with a brain-penetrating bifunctional antibody. Alzheimer's Research & Therapy. 10: 49. PMID 29793530 DOI: 10.1186/s13195-018-0377-8  1
2018 Söllvander S, Nikitidou E, Gallasch L, Zyśk M, Söderberg L, Sehlin D, Lannfelt L, Erlandsson A. The Aβ protofibril selective antibody mAb158 prevents accumulation of Aβ in astrocytes and rescues neurons from Aβ-induced cell death. Journal of Neuroinflammation. 15: 98. PMID 29592816 DOI: 10.1186/s12974-018-1134-4  1
2018 Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, ... ... Lannfelt L, et al. Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 5: 180002. PMID 29360107 DOI: 10.1038/sdata.2018.2  1
2018 Condello C, Lemmin T, Stöhr J, Nick M, Wu Y, Maxwell AM, Watts JC, Caro CD, Oehler A, Keene CD, Bird TD, van Duinen SG, Lannfelt L, Ingelsson M, Graff C, et al. Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 29311311 DOI: 10.1073/Pnas.1714966115  1
2017 Jason F, Fuchsberger C, Mahajan A, Teslovich TM, Agarwala V, Gaulton KJ, Caulkins L, Koesterer R, Ma C, Moutsianas L, McCarthy DJ, Rivas MA, Perry JRB, Sim X, Blackwell TW, ... ... Lannfelt L, et al. Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Scientific Data. 4: 170179. PMID 29257133 DOI: 10.1038/Sdata.2017.179  1
2017 Gustafsson G, Lindström V, Rostami J, Nordström E, Lannfelt L, Bergström J, Ingelsson M, Erlandsson A. Alpha-synuclein oligomer-selective antibodies reduce intracellular accumulation and mitochondrial impairment in alpha-synuclein exposed astrocytes. Journal of Neuroinflammation. 14: 241. PMID 29228971 DOI: 10.1186/s12974-017-1018-z  1
2017 Strawbridge RJ, Silveira A, Hoed MD, Gustafsson S, Luan J, Rybin D, Dupuis J, Li-Gao R, Kavousi M, Dehghan A, Haljas K, Lahti J, Gådin JR, Bäcklund A, de Faire U, ... ... Lannfelt LL, et al. Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation. Atherosclerosis. 266: 196-204. PMID 29040868 DOI: 10.1016/J.Atherosclerosis.2017.09.031  1
2017 Fang XT, Sehlin D, Lannfelt L, Syvänen S, Hultqvist G. Efficient and inexpensive transient expression of multispecific multivalent antibodies in Expi293 cells. Biological Procedures Online. 19: 11. PMID 28932173 DOI: 10.1186/s12575-017-0060-7  1
2017 Velickaite V, Giedraitis V, Ström K, Alafuzoff I, Zetterberg H, Lannfelt L, Kilander L, Larsson E, Ingelsson M. Cognitive function in very old men does not correlate to biomarkers of Alzheimer’s disease Bmc Geriatrics. 17: 208-208. PMID 28886705 DOI: 10.1186/S12877-017-0601-6  1
2017 Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, Lin H, Arking DE, Smith AV, Albert CM, Chaffin M, Tucker NR, Li M, Klarin D, Bihlmeyer NA, ... ... Lannfelt L, et al. Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nature Genetics. 49: 1286. PMID 28747752 DOI: 10.1038/ng0817-1286c  1
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Lannfelt L, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  1
2017 Scott RA, Scott LJ, Mägi R, Marullo L, Gaulton KJ, Kaakinen M, Pervjakova N, Pers TH, Johnson AD, Eicher JD, Jackson AU, Ferreira T, Lee Y, Ma C, Steinthorsdottir V, ... ... Lannfelt L, et al. An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes. PMID 28566273 DOI: 10.2337/Db16-1253  1
2017 Abu Hamdeh S, Waara ER, Möller C, Söderberg L, Basun H, Alafuzoff I, Hillered L, Lannfelt L, Ingelsson M, Marklund N. Rapid amyloid-β oligomer and protofibril accumulation in traumatic brain injury. Brain Pathology (Zurich, Switzerland). PMID 28557010 DOI: 10.1111/Bpa.12532  1
2017 Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, Lin H, Arking DE, Smith AV, Albert CM, Chaffin M, Tucker NR, Li M, Klarin D, Bihlmeyer NA, ... ... Lannfelt L, et al. Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nature Genetics. PMID 28416818 DOI: 10.1038/Ng.3843  1
2017 Wild PS, Felix JF, Schillert A, Teumer A, Chen MH, Leening MJ, Völker U, Großmann V, Brody JA, Irvin MR, Shah SJ, Pramana S, Lieb W, Schmidt R, Stanton AV, ... ... Lannfelt L, et al. Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. The Journal of Clinical Investigation. PMID 28394258 DOI: 10.1172/Jci84840  1
2017 Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, ... ... Lannfelt L, et al. A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk. Diabetes. PMID 28341696 DOI: 10.2337/Db16-1329  1
2017 Westman G, Blomberg J, Yun Z, Lannfelt L, Ingelsson M, Eriksson BM. Decreased HHV-6 IgG in Alzheimer's Disease. Frontiers in Neurology. 8: 40. PMID 28265256 DOI: 10.3389/fneur.2017.00040  1
2017 Almkvist O, Rodriguez-Vieitez E, Thordardottir S, Amberla K, Axelman K, Basun H, Kinhult-Ståhlbom A, Lilius L, Remes A, Wahlund LO, Viitanen M, Lannfelt L, Graff C. Predicting Cognitive Decline across Four Decades in Mutation Carriers and Non-carriers in Autosomal-Dominant Alzheimer's Disease. Journal of the International Neuropsychological Society : Jins. 1-9. PMID 28079014 DOI: 10.1017/S1355617716001028  1
2017 Syvänen S, Fang XT, Hultqvist G, Meier SR, Lannfelt L, Sehlin D. A bispecific Tribody PET radioligand for visualization of amyloid-beta protofibrils - a new concept for neuroimaging. Neuroimage. PMID 28069541 DOI: 10.1016/j.neuroimage.2017.01.004  1
2017 Hultqvist G, Syvänen S, Fang XT, Lannfelt L, Sehlin D. Bivalent Brain Shuttle Increases Antibody Uptake by Monovalent Binding to the Transferrin Receptor. Theranostics. 7: 308-318. PMID 28042336 DOI: 10.7150/thno.17155  1
2016 Almandoz-Gil L, Lindström V, Sigvardson J, Kahle PJ, Lannfelt L, Ingelsson M, Bergström J. Mapping of Surface-Exposed Epitopes of In Vitro and In Vivo Aggregated Species of Alpha-Synuclein. Cellular and Molecular Neurobiology. PMID 28028735 DOI: 10.1007/s10571-016-0454-0  1
2016 Fang XT, Eriksson J, Antoni G, Yngve U, Cato L, Lannfelt L, Sehlin D, Syvänen S. Brain mGluR5 in mice with amyloid beta pathology studied with in vivo [(11)C]ABP688 PET imaging and ex vivo immunoblotting. Neuropharmacology. PMID 27743932 DOI: 10.1016/j.neuropharm.2016.10.009  1
2016 Musunuri S, Khoonsari PE, Mikus M, Wetterhall M, Häggmark A, Lannfelt L, Erlandsson A, Bergquist J, Ingelsson M, Shevchenko G, Nilsson P, Kultima K. Increased Levels of Extracellular Microvesicle Markers and Decreased Levels of Endocytic/Exocytic Proteins in the Alzheimer's Disease Brain. Journal of Alzheimer's Disease : Jad. PMID 27636840 DOI: 10.3233/JAD-160271  1
2016 Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, Grarup N, Sim X, Barnes DR, Witkowska K, Staley JR, Tragante V, Tukiainen T, Yaghootkar H, Masca N, ... ... Lannfelt L, et al. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nature Genetics. PMID 27618447 DOI: 10.1038/Ng.3654  1
2016 Degerman Gunnarsson M, Ingelsson M, Blennow K, Basun H, Lannfelt L, Kilander L. High tau levels in cerebrospinal fluid predict nursing home placement and rapid progression in Alzheimer's disease. Alzheimer's Research & Therapy. 8: 22. PMID 27263933 DOI: 10.1186/S13195-016-0191-0  1
2016 Dumanski JP, Lambert JC, Rasi C, Giedraitis V, Davies H, Grenier-Boley B, Lindgren CM, Campion D, Dufouil C, Pasquier F, Amouyel P, Lannfelt L, Ingelsson M, Kilander L, et al. Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease. American Journal of Human Genetics. PMID 27231129 DOI: 10.1016/J.Ajhg.2016.05.014  1
2016 Söllvander S, Nikitidou E, Brolin R, Söderberg L, Sehlin D, Lannfelt L, Erlandsson A. Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons. Molecular Neurodegeneration. 11: 38. PMID 27176225 DOI: 10.1186/s13024-016-0098-z  1
2016 Logovinsky V, Satlin A, Lai R, Swanson C, Kaplow J, Osswald G, Basun H, Lannfelt L. Safety and tolerability of BAN2401 - a clinical study in Alzheimer's disease with a protofibril selective Aβ antibody. Alzheimer's Research & Therapy. 8: 14. PMID 27048170 DOI: 10.1186/s13195-016-0181-2  1
2016 Gustafsson G, Eriksson F, Möller C, da Fonseca TL, Outeiro TF, Lannfelt L, Bergström J, Ingelsson M. Cellular Uptake of α-Synuclein Oligomer-Selective Antibodies is Enhanced by the Extracellular Presence of α-Synuclein and Mediated via Fcγ Receptors. Cellular and Molecular Neurobiology. PMID 26961542 DOI: 10.1007/S10571-016-0352-5  1
2016 Reinert J, Richard BC, Klafki HW, Friedrich B, Bayer TA, Wiltfang J, Kovacs GG, Ingelsson M, Lannfelt L, Paetau A, Bergquist J, Wirths O. Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer's disease and transgenic mouse models. Acta Neuropathologica Communications. 4: 24. PMID 26955942 DOI: 10.1186/S40478-016-0294-7  1
2016 Khoonsari PE, Häggmark A, Lönnberg M, Mikus M, Kilander L, Lannfelt L, Bergquist J, Ingelsson M, Nilsson P, Kultima K, Shevchenko G. Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease. Plos One. 11: e0150672. PMID 26950848 DOI: 10.1371/journal.pone.0150672  1
2016 Sehlin D, Fang XT, Cato L, Antoni G, Lannfelt L, Syvänen S. Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer's disease. Nature Communications. 7: 10759. PMID 26892305 DOI: 10.1038/ncomms10759  1
2016 Caruso V, Sreedharan S, Carlini VP, Jacobsson JA, Haitina T, Hammer J, Stephansson O, Crona F, Sommer WH, Risérus U, Lannfelt L, Marcus C, Heilig M, de Barioglio SR, Fredriksson R, et al. mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts. Gene. PMID 26827797 DOI: 10.1016/J.Gene.2016.01.044  1
2015 Sato Y, Bernier F, Yamanaka Y, Aoshima K, Oda Y, Ingelsson M, Lannfelt L, Miyashita A, Kuwano R, Ikeuchi T. Reduced plasma desmosterol-to-cholesterol ratio and longitudinal cognitive decline in Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 1: 67-74. PMID 27239493 DOI: 10.1016/j.dadm.2014.11.009  1
2015 Söllvander S, Ekholm-Pettersson F, Brundin RM, Westman G, Kilander L, Paulie S, Lannfelt L, Sehlin D, Piazza F. Increased Number of Plasma B Cells Producing Autoantibodies Against Aβ42 Protofibrils in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 48: 63-72. PMID 26401929 DOI: 10.3233/JAD-150236  1
2015 Sood S, Gallagher IJ, Lunnon K, Rullman E, Keohane A, Crossland H, Phillips BE, Cederholm T, Jensen T, van Loon LJ, Lannfelt L, Kraus WE, Atherton PJ, Howard R, Gustafsson T, et al. A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status. Genome Biology. 16: 185. PMID 26343147 DOI: 10.1186/S13059-015-0750-X  1
2015 Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LD, Moore S, Daria A, Hampel H, Müller V, Giudici C, Nuscher B, Wenninger-Weinzierl A, ... ... Lannfelt L, et al. η-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature. PMID 26322584 DOI: 10.1038/Nature14864  1
2015 Cai Y, Lendel C, Österlund L, Kasrayan A, Lannfelt L, Ingelsson M, Nikolajeff F, Karlsson M, Bergström J. Changes in secondary structure of α-synuclein during oligomerization induced by reactive aldehydes. Biochemical and Biophysical Research Communications. 464: 336-41. PMID 26129771 DOI: 10.1016/j.bbrc.2015.06.154  1
2015 Chase A, Leung W, Tapper W, Jones AV, Knoops L, Rasi C, Forsberg LA, Guglielmelli P, Zoi K, Hall V, Chiecchio L, Eder-Azanza L, Bryant C, Lannfelt L, Docherty L, et al. Profound parental bias associated with chromosome 14 acquired uniparental disomy indicates targeting of an imprinted locus. Leukemia. PMID 26114957 DOI: 10.1038/leu.2015.130  1
2015 Hosp F, Vossfeldt H, Heinig M, Vasiljevic D, Arumughan A, Wyler E, Landthaler M, Hubner N, Wanker EE, Lannfelt L, Ingelsson M, Lalowski M, Voigt A, Selbach M. Quantitative interaction proteomics of neurodegenerative disease proteins. Cell Reports. 11: 1134-46. PMID 25959826 DOI: 10.1016/J.Celrep.2015.04.030  1
2015 O'Callaghan P, Li JP, Lannfelt L, Lindahl U, Zhang X. Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response. The Journal of Biological Chemistry. 290: 14904-14. PMID 25869127 DOI: 10.1074/jbc.M114.634337  1
2015 Mahajan A, Sim X, Ng HJ, Manning A, Rivas MA, Highland HM, Locke AE, Grarup N, Im HK, Cingolani P, Flannick J, Fontanillas P, Fuchsberger C, Gaulton KJ, Teslovich TM, ... ... Lannfelt L, et al. Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. Plos Genetics. 11: e1004876. PMID 25625282 DOI: 10.1371/Journal.Pgen.1004876  1
2015 Dumanski JP, Rasi C, Lönn M, Davies H, Ingelsson M, Giedraitis V, Lannfelt L, Magnusson PK, Lindgren CM, Morris AP, Cesarini D, Johannesson M, Tiensuu Janson E, Lind L, Pedersen NL, et al. Mutagenesis. Smoking is associated with mosaic loss of chromosome Y. Science (New York, N.Y.). 347: 81-3. PMID 25477213 DOI: 10.1126/science.1262092  1
2015 Musunuri S, Kultima K, Richard BC, Ingelsson M, Lannfelt L, Bergquist J, Shevchenko G. Micellar extraction possesses a new advantage for the analysis of Alzheimer's disease brain proteome. Analytical and Bioanalytical Chemistry. 407: 1041-57. PMID 25416231 DOI: 10.1007/s00216-014-8320-8  1
2015 Tucker S, Möller C, Tegerstedt K, Lord A, Laudon H, Sjödahl J, Söderberg L, Spens E, Sahlin C, Waara ER, Satlin A, Gellerfors P, Osswald G, Lannfelt L. The murine version of BAN2401 (mAb158) selectively reduces amyloid-β protofibrils in brain and cerebrospinal fluid of tg-ArcSwe mice. Journal of Alzheimer's Disease : Jad. 43: 575-88. PMID 25096615 DOI: 10.3233/JAD-140741  1
2015 Pannee J, Törnqvist U, Westerlund A, Ingelsson M, Lannfelt L, Brinkmalm G, Persson R, Gobom J, Svensson J, Johansson P, Zetterberg H, Blennow K, Portelius E. Corrigendum to "The amyloid-beta degradation pattern in plasma-A possible tool for clinical trials in Alzheimer's disease" [Neurosci. Lett. 573 (2014) 7-12] DOI: 10.1016/j.neulet.2014.04.041 Neuroscience Letters. 599: 67-68. DOI: 10.1016/j.neulet.2015.05.042  1
2015 Sato Y, Bernier F, Yamanaka Y, Aoshima K, Oda Y, Ingelsson M, Lannfelt L, Miyashita A, Kuwano R, Ikeuchi T. Reduced plasma desmosterol-to-cholesterol ratio and longitudinal cognitive decline in Alzheimer's disease Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1: 67-74. DOI: 10.1016/j.dadm.2014.11.009  1
2015 Hosp F, Vossfeldt H, Heinig M, Vasiljevic D, Arumughan A, Wyler E, Landthaler M, Hubner N, Wanker EE, Lannfelt L, Ingelsson M, Lalowski M, Voigt A, Selbach M. Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins Cell Reports. 11: 1134-1146. DOI: 10.1016/j.celrep.2015.04.030  1
2014 Kvartsberg H, Duits FH, Ingelsson M, Andreasen N, Öhrfelt A, Andersson K, Brinkmalm G, Lannfelt L, Minthon L, Hansson O, Andreasson U, Teunissen CE, Scheltens P, Van der Flier WM, Zetterberg H, et al. Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25533203 DOI: 10.1016/J.Jalz.2014.10.009  1
2014 Benedict C, Byberg L, Cedernaes J, Hogenkamp PS, Giedratis V, Kilander L, Lind L, Lannfelt L, Schiöth HB. Self-reported sleep disturbance is associated with Alzheimer's disease risk in men. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25438949 DOI: 10.1016/J.Jalz.2014.08.104  1
2014 Lannfelt L, Möller C, Basun H, Osswald G, Sehlin D, Satlin A, Logovinsky V, Gellerfors P. Perspectives on future Alzheimer therapies: amyloid-β protofibrils - a new target for immunotherapy with BAN2401 in Alzheimer's disease. Alzheimer's Research & Therapy. 6: 16. PMID 25031633 DOI: 10.1186/alzrt246  1
2014 Holmes MV, Dale CE, Zuccolo L, Silverwood RJ, Guo Y, Ye Z, Prieto-Merino D, Dehghan A, Trompet S, Wong A, Cavadino A, Drogan D, Padmanabhan S, Li S, Yesupriya A, ... ... Lannfelt L, et al. Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. Bmj (Clinical Research Ed.). 349: g4164. PMID 25011450 DOI: 10.1136/Bmj.G4164  1
2014 Watts JC, Condello C, Stöhr J, Oehler A, Lee J, DeArmond SJ, Lannfelt L, Ingelsson M, Giles K, Prusiner SB. Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients. Proceedings of the National Academy of Sciences of the United States of America. 111: 10323-8. PMID 24982139 DOI: 10.1073/Pnas.1408900111  1
2014 Lindström V, Fagerqvist T, Nordström E, Eriksson F, Lord A, Tucker S, Andersson J, Johannesson M, Schell H, Kahle PJ, Möller C, Gellerfors P, Bergström J, Lannfelt L, Ingelsson M. Immunotherapy targeting α-synuclein protofibrils reduced pathology in (Thy-1)-h[A30P] α-synuclein mice. Neurobiology of Disease. 69: 134-43. PMID 24851801 DOI: 10.1016/j.nbd.2014.05.009  1
2014 Westman G, Berglund D, Widén J, Ingelsson M, Korsgren O, Lannfelt L, Sehlin D, Lidehall AK, Eriksson BM. Increased inflammatory response in cytomegalovirus seropositive patients with Alzheimer's disease. Plos One. 9: e96779. PMID 24804776 DOI: 10.1371/journal.pone.0096779  1
2014 Pannee J, Törnqvist U, Westerlund A, Ingelsson M, Lannfelt L, Brinkmalm G, Persson R, Gobom J, Svensson J, Johansson P, Zetterberg H, Blennow K, Portelius E. The amyloid-β degradation pattern in plasma--a possible tool for clinical trials in Alzheimer's disease. Neuroscience Letters. 573: 7-12. PMID 24796810 DOI: 10.1016/j.neulet.2014.04.041  1
2014 Forsberg LA, Rasi C, Malmqvist N, Davies H, Pasupulati S, Pakalapati G, Sandgren J, Diaz de StÃ¥hl T, Zaghlool A, Giedraitis V, Lannfelt L, Score J, Cross NC, Absher D, Janson ET, et al. Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer. Nature Genetics. 46: 624-8. PMID 24777449 DOI: 10.1038/ng.2966  1
2014 Guzmán EA, Bouter Y, Richard BC, Lannfelt L, Ingelsson M, Paetau A, Verkkoniemi-Ahola A, Wirths O, Bayer TA. Abundance of Aβ₅-x like immunoreactivity in transgenic 5XFAD, APP/PS1KI and 3xTG mice, sporadic and familial Alzheimer's disease. Molecular Neurodegeneration. 9: 13. PMID 24694184 DOI: 10.1186/1750-1326-9-13  1
2014 Musunuri S, Wetterhall M, Ingelsson M, Lannfelt L, Artemenko K, Bergquist J, Kultima K, Shevchenko G. Quantification of the brain proteome in Alzheimer's disease using multiplexed mass spectrometry. Journal of Proteome Research. 13: 2056-68. PMID 24606058 DOI: 10.1021/pr401202d  1
2014 Lannfelt L, Relkin NR, Siemers ER. Amyloid-ß-directed immunotherapy for Alzheimer's disease. Journal of Internal Medicine. 275: 284-95. PMID 24605809 DOI: 10.1111/joim.12168  1
2014 Kivipelto M, Mangialasche F, Solomon A, Johansson G, Lannfelt L, Fratiglioni L, Winblad B. 9th Key symposium introduction: updating Alzheimer's disease diagnosis implications for prevention and treatment. Journal of Internal Medicine. 275: 202-3. PMID 24605804 DOI: 10.1111/Joim.12193  1
2014 Lindström V, Ihse E, Fagerqvist T, Bergström J, Nordström E, Möller C, Lannfelt L, Ingelsson M. Immunotherapy targeting α-synuclein, with relevance for future treatment of Parkinson's disease and other Lewy body disorders. Immunotherapy. 6: 141-53. PMID 24491088 DOI: 10.2217/imt.13.162  1
2014 O'Callaghan P, Noborn F, Sehlin D, Li JP, Lannfelt L, Lindahl U, Zhang X. Apolipoprotein E increases cell association of amyloid-β 40 through heparan sulfate and LRP1 dependent pathways. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 21: 76-87. PMID 24491019 DOI: 10.3109/13506129.2013.879643  1
2014 Benedict C, Cedernaes J, Giedraitis V, Nilsson EK, Hogenkamp PS, VÃ¥gesjö E, Massena S, Pettersson U, Christoffersson G, Phillipson M, Broman JE, Lannfelt L, Zetterberg H, Schiöth HB. Acute sleep deprivation increases serum levels of neuron-specific enolase (NSE) and S100 calcium binding protein B (S-100B) in healthy young men. Sleep. 37: 195-8. PMID 24470708 DOI: 10.5665/Sleep.3336  1
2014 Reinert J, Martens H, Huettenrauch M, Kolbow T, Lannfelt L, Ingelsson M, Paetau A, Verkkoniemi-Ahola A, Bayer TA, Wirths O. Aβ38 in the brains of patients with sporadic and familial Alzheimer's disease and transgenic mouse models. Journal of Alzheimer's Disease : Jad. 39: 871-81. PMID 24305500 DOI: 10.3233/Jad-131373  1
2014 Degerman Gunnarsson M, Lannfelt L, Ingelsson M, Basun H, Kilander L. High tau levels in cerebrospinal fluid predict rapid decline and increased dementia mortality in Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 37: 196-206. PMID 24157938 DOI: 10.1159/000355556  1
2013 Degerman Gunnarsson M, Lindau M, Santillo AF, Wall A, Engler H, Lannfelt L, Basun H, Kilander L. Re-evaluation of clinical dementia diagnoses with pittsburgh compound B positron emission tomography. Dementia and Geriatric Cognitive Disorders Extra. 3: 472-81. PMID 24516415 DOI: 10.1159/000356273  1
2013 Gumucio A, Lannfelt L, Nilsson LN. Lack of exon 10 in the murine tau gene results in mild sensorimotor defects with aging. Bmc Neuroscience. 14: 148. PMID 24261309 DOI: 10.1186/1471-2202-14-148  1
2013 Kalimo H, Lalowski M, Bogdanovic N, Philipson O, Bird TD, Nochlin D, Schellenberg GD, Brundin R, Olofsson T, Soliymani R, Baumann M, Wirths O, Bayer TA, Nilsson LN, Basun H, ... Lannfelt L, et al. The Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated Aβ. Acta Neuropathologica Communications. 1: 60. PMID 24252272 DOI: 10.1186/2051-5960-1-60  1
2013 Antonios G, Saiepour N, Bouter Y, Richard BC, Paetau A, Verkkoniemi-Ahola A, Lannfelt L, Ingelsson M, Kovacs GG, Pillot T, Wirths O, Bayer TA. N-truncated Abeta starting with position four: early intraneuronal accumulation and rescue of toxicity using NT4X-167, a novel monoclonal antibody. Acta Neuropathologica Communications. 1: 56. PMID 24252153 DOI: 10.1186/2051-5960-1-56  1
2013 Westman G, Lidehall AK, Magnusson P, Ingelsson M, Kilander L, Lannfelt L, Korsgren O, Eriksson BM. Decreased proportion of cytomegalovirus specific CD8 T-cells but no signs of general immunosenescence in Alzheimer's disease. Plos One. 8: e77921. PMID 24155977 DOI: 10.1371/journal.pone.0077921  1
2013 Rubio-Moscardo F, Setó-Salvia N, Pera M, Bosch-Morató M, Plata C, Belbin O, Gené G, Dols-Icardo O, Ingelsson M, Helisalmi S, Soininen H, Hiltunen M, Giedraitis V, Lannfelt L, Frank A, et al. Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis. Plos One. 8: e74203. PMID 24069280 DOI: 10.1371/Journal.Pone.0074203  1
2013 Fagerqvist T, Näsström T, Ihse E, Lindström V, Sahlin C, Tucker SM, Kasaryan A, Karlsson M, Nikolajeff F, Schell H, Outeiro TF, Kahle PJ, Lannfelt L, Ingelsson M, Bergström J. Off-pathway α-synuclein oligomers seem to alter α-synuclein turnover in a cell model but lack seeding capability in vivo. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 20: 233-44. PMID 24053224 DOI: 10.3109/13506129.2013.835726  1
2013 Magnusson K, Sehlin D, Syvänen S, Svedberg MM, Philipson O, Söderberg L, Tegerstedt K, Holmquist M, Gellerfors P, Tolmachev V, Antoni G, Lannfelt L, Hall H, Nilsson LN. Specific uptake of an amyloid-β protofibril-binding antibody-tracer in AβPP transgenic mouse brain. Journal of Alzheimer's Disease : Jad. 37: 29-40. PMID 23780660 DOI: 10.3233/JAD-130029  1
2013 Roed L, Grave G, Lindahl T, Rian E, Horndalsveen PO, Lannfelt L, Nilsson C, Swenson F, Lönneborg A, Sharma P, Sjögren M. Prediction of mild cognitive impairment that evolves into Alzheimer's disease dementia within two years using a gene expression signature in blood: a pilot study. Journal of Alzheimer's Disease : Jad. 35: 611-21. PMID 23478308 DOI: 10.3233/JAD-122404  1
2013 Fagerqvist T, Lindström V, Nordström E, Lord A, Tucker SM, Su X, Sahlin C, Kasrayan A, Andersson J, Welander H, Näsström T, Holmquist M, Schell H, Kahle PJ, Kalimo H, ... ... Lannfelt L, et al. Monoclonal antibodies selective for α-synuclein oligomers/protofibrils recognize brain pathology in Lewy body disorders and α-synuclein transgenic mice with the disease-causing A30P mutation. Journal of Neurochemistry. 126: 131-44. PMID 23363402 DOI: 10.1111/Jnc.12175  1
2013 Olsson B, Hertze J, Ohlsson M, Nägga K, Höglund K, Basun H, Annas P, Lannfelt L, Andreasen N, Minthon L, Zetterberg H, Blennow K, Hansson O. Cerebrospinal fluid levels of heart fatty acid binding protein are elevated prodromally in Alzheimer's disease and vascular dementia. Journal of Alzheimer's Disease : Jad. 34: 673-9. PMID 23254629 DOI: 10.3233/JAD-121384  1
2013 Olsson B, Hertze J, Lautner R, Zetterberg H, Nägga K, Höglund K, Basun H, Annas P, Lannfelt L, Andreasen N, Minthon L, Blennow K, Hansson O. Microglial markers are elevated in the prodromal phase of Alzheimer's disease and vascular dementia. Journal of Alzheimer's Disease : Jad. 33: 45-53. PMID 22890100 DOI: 10.3233/JAD-2012-120787  1
2013 Lambert JC, Grenier-Boley B, Harold D, Zelenika D, Chouraki V, Kamatani Y, Sleegers K, Ikram MA, Hiltunen M, Reitz C, Mateo I, Feulner T, Bullido M, Galimberti D, Concari L, ... ... Lannfelt L, et al. Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease. Molecular Psychiatry. 18: 461-70. PMID 22430674 DOI: 10.1038/Mp.2012.14  1
2013 Lambert JC, Grenier-Boley B, Harold D, Zelenika D, Chouraki V, Kamatani Y, Sleegers K, Ikram MA, Hiltunen M, Reitz C, Mateo I, Feulner T, Bullido M, Galimberti D, Concari L, ... ... Lannfelt L, et al. Erratum: Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease (Molecular Psychiatry (2013) 18 (521) DOI: 10.1038/mp.2012.75)) Molecular Psychiatry. 18. DOI: 10.1038/Mp.2012.75  1
2013 Schjeide B, Borovecki F, Clarimón J, Faltraco F, Giedraitis V, Ingelsson M, Hampel H, Hooli B, Kilander L, Kirchheiner J, Klepac N, Kurz A, Lannfelt L, Lill C, Lleó A, et al. Assessment of Alzheimer's disease risk genes with CSF-biomarker levels Alzheimers & Dementia. 9: 179. DOI: 10.1016/J.Jalz.2013.05.294  1
2013 Swanson C, Kaplow JM, Mastroeni D, Rogers J, Waara ER, Navia B, Lai R, Logovinsky V, Möller C, Lannfelt L, Satlin A. Pharmacology of BAN2401: A monoclonal antibody selective for beta-amyloid protofibrils Alzheimers & Dementia. 9: 809. DOI: 10.1016/J.Jalz.2013.05.1679  1
2013 Navia B, Perdomo C, Krause S, Kaplow JM, Koyama A, Teceno T, Gershman B, Logovinsky V, Swanson C, Lai R, Möller C, Lannfelt L, Satlin A, McCracken P. A multimodal imaging study of mAb158, a murine monoclonal antibody with high selectivity for amyloid protofibrils, in Tg2576 mice Alzheimers & Dementia. 9: 808. DOI: 10.1016/J.Jalz.2013.05.1675  1
2013 Kaplow JM, Kusnetov G, Mastroeni D, Navia B, Kumar N, Biscaro B, Koyama A, Möller C, Lai R, Swanson C, Logovinsky V, Lannfelt L, Satlin A, Rogers J. Microglial involvement and amyloid reduction with BAN2401/mAb158, a monoclonal antibody with high selectivity for protofibrils: In vitro and ex vivo analyses Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.1674  1
2013 Ingelsson M, Fagerqvist T, Näsström T, Ihse E, Lindström V, Sahlin C, Tucker S, Kasrayan A, Karlsson M, Nikolajeff F, Nath S, Agholme L, Outeiro T, Hallbeck M, Lannfelt L, et al. Alpha-synuclein oligomers can act as seed in a fibrillation assay but do not cause increased aggregation in living cells Alzheimers & Dementia. 9: 721. DOI: 10.1016/J.Jalz.2013.05.1442  1
2013 Lai R, Logovinsky V, Kaplow JM, Gu K, Yu Y, Möller C, Navia B, Swanson C, Lannfelt L, Satlin A. A first-in-human study of BAN2401, a novel monoclonal antibody against beta-amyloid protofibrils Alzheimers & Dementia. 9: 689. DOI: 10.1016/J.Jalz.2013.04.358  1
2012 Höglund K, Bogstedt A, Fabre S, Aziz A, Annas P, Basun H, Minthon L, Lannfelt L, Blennow K, Andreasen N. Longitudinal stability evaluation of biomarkers and their correlation in cerebrospinal fluid and plasma from patients with Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 32: 939-47. PMID 22936008 DOI: 10.3233/JAD-2012-120976  1
2012 Diógenes MJ, Dias RB, Rombo DM, Vicente Miranda H, Maiolino F, Guerreiro P, Näsström T, Franquelim HG, Oliveira LM, Castanho MA, Lannfelt L, Bergström J, Ingelsson M, Quintas A, Sebastião AM, et al. Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11750-62. PMID 22915117 DOI: 10.1523/Jneurosci.0234-12.2012  1
2012 Olsson B, Malmeström C, Basun H, Annas P, Höglund K, Lannfelt L, Andreasen N, Zetterberg H, Blennow K. Extreme stability of chitotriosidase in cerebrospinal fluid makes it a suitable marker for microglial activation in clinical trials. Journal of Alzheimer's Disease : Jad. 32: 273-6. PMID 22785399 DOI: 10.3233/JAD-2012-120931  1
2012 Rönnemaa E, Zethelius B, Vessby B, Lannfelt L, Byberg L, Kilander L. Serum fatty-acid composition and the risk of Alzheimer's disease: a longitudinal population-based study. European Journal of Clinical Nutrition. 66: 885-90. PMID 22713770 DOI: 10.1038/ejcn.2012.63  1
2012 Zhang X, Wang B, O'Callaghan P, Hjertström E, Jia J, Gong F, Zcharia E, Nilsson LN, Lannfelt L, Vlodavsky I, Lindahl U, Li JP. Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain. Acta Neuropathologica. 124: 465-78. PMID 22692572 DOI: 10.1007/s00401-012-0997-1  1
2012 Sehlin D, Englund H, Simu B, Karlsson M, Ingelsson M, Nikolajeff F, Lannfelt L, Pettersson FE. Large aggregates are the major soluble Aβ species in AD brain fractionated with density gradient ultracentrifugation. Plos One. 7: e32014. PMID 22355408 DOI: 10.1371/journal.pone.0032014  1
2012 Forsberg LA, Rasi C, Razzaghian HR, Pakalapati G, Waite L, Thilbeault KS, Ronowicz A, Wineinger NE, Tiwari HK, Boomsma D, Westerman MP, Harris JR, Lyle R, Essand M, Eriksson F, ... ... Lannfelt L, et al. Age-related somatic structural changes in the nuclear genome of human blood cells. American Journal of Human Genetics. 90: 217-28. PMID 22305530 DOI: 10.1016/J.Ajhg.2011.12.009  1
2012 Philipson O, Lord A, Lalowski M, Soliymani R, Baumann M, Thyberg J, Bogdanovic N, Olofsson T, Tjernberg LO, Ingelsson M, Lannfelt L, Kalimo H, Nilsson LN. The Arctic amyloid-β precursor protein (AβPP) mutation results in distinct plaques and accumulation of N- and C-truncated Aβ. Neurobiology of Aging. 33: 1010.e1-13. PMID 22118948 DOI: 10.1016/J.Neurobiolaging.2011.10.022  1
2012 Jacobsson JA, Rask-Andersen M, Risérus U, Moschonis G, Koumpitski A, Chrousos GP, Lannfelt L, Marcus C, Gyllensten U, Schiöth HB, Fredriksson R. Genetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children. International Journal of Obesity (2005). 36: 119-29. PMID 21304485 DOI: 10.1038/ijo.2011.11  1
2011 Näsström T, Gonçalves S, Sahlin C, Nordström E, Screpanti Sundquist V, Lannfelt L, Bergström J, Outeiro TF, Ingelsson M. Antibodies against alpha-synuclein reduce oligomerization in living cells. Plos One. 6: e27230. PMID 22073131 DOI: 10.1371/Journal.Pone.0027230  1
2011 Yang J, Lunde LK, Nuntagij P, Oguchi T, Camassa LM, Nilsson LN, Lannfelt L, Xu Y, Amiry-Moghaddam M, Ottersen OP, Torp R. Loss of astrocyte polarization in the tg-ArcSwe mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 27: 711-22. PMID 21891870 DOI: 10.3233/JAD-2011-110725  1
2011 Santillo AF, Gambini JP, Lannfelt L, LÃ¥ngström B, Ulla-Marja L, Kilander L, Engler H. In vivo imaging of astrocytosis in Alzheimer's disease: an ¹¹C-L-deuteriodeprenyl and PIB PET study. European Journal of Nuclear Medicine and Molecular Imaging. 38: 2202-8. PMID 21853308 DOI: 10.1007/s00259-011-1895-9  1
2011 Welander H, Bontha SV, Näsström T, Karlsson M, Nikolajeff F, Danzer K, Kostka M, Kalimo H, Lannfelt L, Ingelsson M, Bergström J. Gelsolin co-occurs with Lewy bodies in vivo and accelerates α-synuclein aggregation in vitro. Biochemical and Biophysical Research Communications. 412: 32-8. PMID 21798243 DOI: 10.1016/J.Bbrc.2011.07.027  1
2011 Rönnemaa E, Zethelius B, Lannfelt L, Kilander L. Vascular risk factors and dementia: 40-year follow-up of a population-based cohort. Dementia and Geriatric Cognitive Disorders. 31: 460-6. PMID 21791923 DOI: 10.1159/000330020  1
2011 Benedict C, Jacobsson JA, Rönnemaa E, Sällman-Almén M, Brooks S, Schultes B, Fredriksson R, Lannfelt L, Kilander L, Schiöth HB. The fat mass and obesity gene is linked to reduced verbal fluency in overweight and obese elderly men. Neurobiology of Aging. 32: 1159.e1-5. PMID 21458110 DOI: 10.1016/J.Neurobiolaging.2011.02.006  1
2011 Näsström T, Fagerqvist T, Barbu M, Karlsson M, Nikolajeff F, Kasrayan A, Ekberg M, Lannfelt L, Ingelsson M, Bergström J. The lipid peroxidation products 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote the formation of α-synuclein oligomers with distinct biochemical, morphological, and functional properties. Free Radical Biology & Medicine. 50: 428-37. PMID 21130160 DOI: 10.1016/j.freeradbiomed.2010.11.027  1
2011 Skoglund L, Matsui T, Freeman SH, Wallin A, Blom ES, Frosch MP, Growdon JH, Hyman BT, Lannfelt L, Ingelsson M, Glaser A. Novel progranulin mutation detected in 2 patients with FTLD. Alzheimer Disease and Associated Disorders. 25: 173-8. PMID 20975516 DOI: 10.1097/Wad.0B013E3181Fbc22C  1
2011 Sehlin D, Hedlund M, Lord A, Englund H, Gellerfors P, Paulie S, Lannfelt L, Pettersson FE. Heavy-chain complementarity-determining regions determine conformation selectivity of anti-aβ antibodies. Neuro-Degenerative Diseases. 8: 117-23. PMID 20714111 DOI: 10.1159/000316530  1
2011 Schöll M, Almkvist O, Axelman K, Stefanova E, Wall A, Westman E, LÃ¥ngström B, Lannfelt L, Graff C, Nordberg A. Glucose metabolism and PIB binding in carriers of a His163Tyr presenilin 1 mutation. Neurobiology of Aging. 32: 1388-99. PMID 19796846 DOI: 10.1016/J.Neurobiolaging.2009.08.016  1
2011 Marcello A, Wirths O, Schneider-Axmann T, Degerman-Gunnarsson M, Lannfelt L, Bayer TA. Reduced levels of IgM autoantibodies against N-truncated pyroglutamate Aβ in plasma of patients with Alzheimer's disease. Neurobiology of Aging. 32: 1379-87. PMID 19781815 DOI: 10.1016/j.neurobiolaging.2009.08.011  1
2011 Ku BD, Na DL, Moon SY, Kim SY, Seo SW, Cheong H, Park KW, Park KH, Lee J, Cha KR, Shim YS, Youn YC, Chung C, Kim JE, Kang HY, ... ... Lannfelt L, et al. Contents Vol. 31, 2011 Dementia and Geriatric Cognitive Disorders. 31. DOI: 10.1159/000330829  1
2010 Sehlin D, Söllvander S, Paulie S, Brundin R, Ingelsson M, Lannfelt L, Pettersson FE, Englund H. Interference from heterophilic antibodies in amyloid-β oligomer ELISAs. Journal of Alzheimer's Disease : Jad. 21: 1295-301. PMID 21504116 DOI: 10.3233/JAD-2010-100609  1
2010 Blom ES, Wang Y, Skoglund L, Hansson AC, Ubaldi M, Lourdusamy A, Sommer WH, Mielke M, Hyman BT, Heilig M, Lannfelt L, Nilsson LN, Ingelsson M. Increased mRNA Levels of TCF7L2 and MYC of the Wnt Pathway in Tg-ArcSwe Mice and Alzheimer's Disease Brain. International Journal of Alzheimer's Disease. 2011: 936580. PMID 21234373 DOI: 10.4061/2011/936580  1
2010 Lannfelt L, Pettersson FE, Nilsson LN. Translating research on brain aging into public health: a new type of immunotherapy for Alzheimer's disease. Nutrition Reviews. 68: S128-34. PMID 21091946 DOI: 10.1111/j.1753-4887.2010.00347.x  1
2010 Wirths O, Erck C, Martens H, Harmeier A, Geumann C, Jawhar S, Kumar S, Multhaup G, Walter J, Ingelsson M, Degerman-Gunnarsson M, Kalimo H, Huitinga I, Lannfelt L, Bayer TA. Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis. The Journal of Biological Chemistry. 285: 41517-24. PMID 20971852 DOI: 10.1074/Jbc.M110.178707  1
2010 Sundelöf J, Sundström J, Hansson O, Eriksdotter-Jönhagen M, Giedraitis V, Larsson A, Degerman-Gunnarsson M, Ingelsson M, Minthon L, Blennow K, Kilander L, Basun H, Lannfelt L. Higher cathepsin B levels in plasma in Alzheimer's disease compared to healthy controls. Journal of Alzheimer's Disease : Jad. 22: 1223-30. PMID 20930303 DOI: 10.3233/JAD-2010-101023  1
2010 Kamali-Moghaddam M, Pettersson FE, Wu D, Englund H, Darmanis S, Lord A, Tavoosidana G, Sehlin D, Gustafsdottir S, Nilsson LN, Lannfelt L, Landegren U. Sensitive detection of Aβ protofibrils by proximity ligation--relevance for Alzheimer's disease. Bmc Neuroscience. 11: 124. PMID 20923550 DOI: 10.1186/1471-2202-11-124  1
2010 Lambert JC, Sleegers K, González-Pérez A, Ingelsson M, Beecham GW, Hiltunen M, Combarros O, Bullido MJ, Brouwers N, Bettens K, Berr C, Pasquier F, Richard F, Dekosky ST, Hannequin D, ... ... Lannfelt L, et al. The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study. Journal of Alzheimer's Disease : Jad. 22: 247-55. PMID 20847397 DOI: 10.3233/Jad-2010-100933  1
2010 Sandberg A, Luheshi LM, Söllvander S, Pereira de Barros T, Macao B, Knowles TP, BiverstÃ¥l H, Lendel C, Ekholm-Petterson F, Dubnovitsky A, Lannfelt L, Dobson CM, Härd T. Stabilization of neurotoxic Alzheimer amyloid-beta oligomers by protein engineering. Proceedings of the National Academy of Sciences of the United States of America. 107: 15595-600. PMID 20713699 DOI: 10.1073/Pnas.1001740107  1
2010 Codita A, Gumucio A, Lannfelt L, Gellerfors P, Winblad B, Mohammed AH, Nilsson LN. Impaired behavior of female tg-ArcSwe APP mice in the IntelliCage: A longitudinal study. Behavioural Brain Research. 215: 83-94. PMID 20615433 DOI: 10.1016/J.Bbr.2010.06.034  1
2010 Sundelöf J, Sundström J, Hansson O, Eriksdotter-Jönhagen M, Giedraitis V, Larsson A, Degerman-Gunnarsson M, Ingelsson M, Minthon L, Blennow K, Kilander L, Basun H, Lannfelt L. Cystatin C levels are positively correlated with both Abeta42 and tau levels in cerebrospinal fluid in persons with Alzheimer's disease, mild cognitive impairment, and healthy controls. Journal of Alzheimer's Disease : Jad. 21: 471-8. PMID 20555147 DOI: 10.3233/JAD-2010-091594  1
2010 Wiberg H, Ek P, Pettersson FE, Lannfelt L, Emmer A, Roeraade J. Separation and characterization of aggregated species of amyloid-beta peptides. Analytical and Bioanalytical Chemistry. 397: 2357-66. PMID 20502882 DOI: 10.1007/s00216-010-3839-9  1
2010 Israelsson C, Bengtsson H, Lobell A, Nilsson LN, Kylberg A, Isaksson M, Wootz H, Lannfelt L, Kullander K, Hillered L, Ebendal T. Appearance of Cxcl10-expressing cell clusters is common for traumatic brain injury and neurodegenerative disorders. The European Journal of Neuroscience. 31: 852-63. PMID 20374285 DOI: 10.1111/J.1460-9568.2010.07105.X  1
2010 Degerman Gunnarsson M, Lindau M, Wall A, Blennow K, Darreh-Shori T, Basu S, Nordberg A, Larsson A, Lannfelt L, Basun H, Kilander L. Pittsburgh compound-B and Alzheimer's disease biomarkers in CSF, plasma and urine: An exploratory study. Dementia and Geriatric Cognitive Disorders. 29: 204-12. PMID 20332638 DOI: 10.1159/000281832  1
2010 Faux NG, Ritchie CW, Gunn A, Rembach A, Tsatsanis A, Bedo J, Harrison J, Lannfelt L, Blennow K, Zetterberg H, Ingelsson M, Masters CL, Tanzi RE, Cummings JL, Herd CM, et al. PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses. Journal of Alzheimer's Disease : Jad. 20: 509-16. PMID 20164561 DOI: 10.3233/Jad-2010-1390  1
2010 Philipson O, Lord A, Gumucio A, O'Callaghan P, Lannfelt L, Nilsson LN. Animal models of amyloid-beta-related pathologies in Alzheimer's disease. The Febs Journal. 277: 1389-409. PMID 20136653 DOI: 10.1111/j.1742-4658.2010.07564.x  1
2010 Sandwall E, O'Callaghan P, Zhang X, Lindahl U, Lannfelt L, Li JP. Heparan sulfate mediates amyloid-beta internalization and cytotoxicity. Glycobiology. 20: 533-41. PMID 20053627 DOI: 10.1093/glycob/cwp205  1
2010 Wesnes K, Edgar C, Andreasen N, Annas P, Basun H, Lannfelt L, Zetterberg H, Blennow K, Minthon L. Computerized cognition assessment during acetylcholinesterase inhibitor treatment in Alzheimer's disease. Acta Neurologica Scandinavica. 122: 270-7. PMID 20047570 DOI: 10.1111/j.1600-0404.2009.01309.x  1
2010 Giedraitis V, Glaser A, Sarajärvi T, Brundin R, Gunnarsson MD, Schjeide BM, Tanzi RE, Helisalmi S, Pirttilä T, Kilander L, Lannfelt L, Soininen H, Bertram L, Ingelsson M, Hiltunen M. CALHM1 P86L polymorphism does not alter amyloid-beta or tau in cerebrospinal fluid. Neuroscience Letters. 469: 265-7. PMID 20005921 DOI: 10.1016/J.Neulet.2009.12.011  1
2010 Petzold A, Altintas A, Andreoni L, Bartos A, Berthele A, Blankenstein MA, Buee L, Castellazzi M, Cepok S, Comabella M, Constantinescu CS, Deisenhammer F, Deniz G, Erten G, Espiño M, ... ... Lannfelt L, et al. Neurofilament ELISA validation. Journal of Immunological Methods. 352: 23-31. PMID 19857497 DOI: 10.1016/J.Jim.2009.09.014  1
2010 Wirths O, Bethge T, Marcello A, Harmeier A, Jawhar S, Lucassen PJ, Multhaup G, Brody DL, Esparza T, Ingelsson M, Kalimo H, Lannfelt L, Bayer TA. Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer's disease cases. Journal of Neural Transmission (Vienna, Austria : 1996). 117: 85-96. PMID 19823761 DOI: 10.1007/S00702-009-0314-X  1
2010 Wiig EH, Annas P, Basun H, Andreasen N, Lannfelt L, Zetterberg H, Blennow K, Minthon L. The stability of AQT processing speed, ADAS-Cog and MMSE during acetylcholinesterase inhibitor treatment in Alzheimer's disease. Acta Neurologica Scandinavica. 121: 186-93. PMID 19785641 DOI: 10.1111/j.1600-0404.2009.01160.x  1
2009 Jacobsson JA, Risérus U, Axelsson T, Lannfelt L, Schiöth HB, Fredriksson R. The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924. Bmc Medical Genetics. 10: 131. PMID 20003232 DOI: 10.1186/1471-2350-10-131  1
2009 Blom ES, Giedraitis V, Arepalli S, Hamshere ML, Adighibe O, Goate A, Williams J, Lannfelt L, Hardy J, Vrièze FW, Glaser A. Further analysis of previously implicated linkage regions for Alzheimer's disease in affected relative pairs. Bmc Medical Genetics. 10: 122. PMID 19951422 DOI: 10.1186/1471-2350-10-122  1
2009 Skoglund L, Ingvast S, Matsui T, Freeman SH, Frosch MP, Brundin R, Giedraitis V, Growdon JH, Hyman BT, Lannfelt L, Ingelsson M, Glaser A. No evidence of PGRN or MAPT gene dosage alterations in a collection of patients with frontotemporal lobar degeneration. Dementia and Geriatric Cognitive Disorders. 28: 471-5. PMID 19940479 DOI: 10.1159/000260046  1
2009 Lord A, Gumucio A, Englund H, Sehlin D, Sundquist VS, Söderberg L, Möller C, Gellerfors P, Lannfelt L, Pettersson FE, Nilsson LN. An amyloid-beta protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease. Neurobiology of Disease. 36: 425-34. PMID 19703562 DOI: 10.1016/j.nbd.2009.08.007  1
2009 Philipson O, Lannfelt L, Nilsson LN. Genetic and pharmacological evidence of intraneuronal Abeta accumulation in APP transgenic mice. Febs Letters. 583: 3021-6. PMID 19683527 DOI: 10.1016/j.febslet.2009.08.009  1
2009 Ingelsson M, Basun H, Pettersson FE, Kilander L, Nilsson LN, Lannfelt L. [Rare mutations aim toward future treatment]. Lã¤Kartidningen. 106: 1396-400. PMID 19585838  1
2009 Santillo AF, Skoglund L, Lindau M, Eeg-Olofsson KE, Tovi M, Engler H, Brundin RM, Ingvast S, Lannfelt L, Glaser A, Kilander L. Frontotemporal dementia-amyotrophic lateral sclerosis complex is simulated by neurodegeneration with brain iron accumulation. Alzheimer Disease and Associated Disorders. 23: 298-300. PMID 19568152 DOI: 10.1097/WAD.0b013e3181a2b76b  1
2009 Marklund N, Morales D, Clausen F, HÃ¥nell A, Kiwanuka O, Pitkänen A, Gimbel DA, Philipson O, Lannfelt L, Hillered L, Strittmatter SM, McIntosh TK. Functional outcome is impaired following traumatic brain injury in aging Nogo-A/B-deficient mice. Neuroscience. 163: 540-51. PMID 19555742 DOI: 10.1016/J.Neuroscience.2009.06.042  1
2009 Sundelöf J, Kilander L, Helmersson J, Larsson A, Rönnemaa E, Degerman-Gunnarsson M, Sjögren P, Basun H, Lannfelt L, Basu S. Systemic tocopherols and F2-isoprostanes and the risk of Alzheimer's disease and dementia: a prospective population-based study. Journal of Alzheimer's Disease : Jad. 18: 71-8. PMID 19542632 DOI: 10.3233/JAD-2009-1125  1
2009 Sundelöf J, Kilander L, Helmersson J, Larsson A, Rönnemaa E, Degerman-Gunnarsson M, Basun H, Lannfelt L, Basu S. Systemic inflammation and the risk of Alzheimer's disease and dementia: a prospective population-based study. Journal of Alzheimer's Disease : Jad. 18: 79-87. PMID 19542629 DOI: 10.3233/JAD-2009-1126  1
2009 Englund H, Degerman Gunnarsson M, Brundin RM, Hedlund M, Kilander L, Lannfelt L, Pettersson FE. Oligomerization partially explains the lowering of Abeta42 in Alzheimer's disease cerebrospinal fluid. Neuro-Degenerative Diseases. 6: 139-47. PMID 19521063 DOI: 10.1159/000225376  1
2009 Rönnemaa E, Zethelius B, Sundelöf J, Sundström J, Degerman-Gunnarsson M, Lannfelt L, Berne C, Kilander L. Glucose metabolism and the risk of Alzheimer's disease and dementia: a population-based 12 year follow-up study in 71-year-old men. Diabetologia. 52: 1504-10. PMID 19455303 DOI: 10.1007/s00125-009-1393-9  1
2009 Blom ES, Giedraitis V, Zetterberg H, Fukumoto H, Blennow K, Hyman BT, Irizarry MC, Wahlund LO, Lannfelt L, Ingelsson M. Rapid progression from mild cognitive impairment to Alzheimer's disease in subjects with elevated levels of tau in cerebrospinal fluid and the APOE epsilon4/epsilon4 genotype. Dementia and Geriatric Cognitive Disorders. 27: 458-64. PMID 19420940 DOI: 10.1159/000216841  1
2009 Marcello A, Wirths O, Schneider-Axmann T, Degerman-Gunnarsson M, Lannfelt L, Bayer TA. Circulating immune complexes of Abeta and IgM in plasma of patients with Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 116: 913-20. PMID 19415450 DOI: 10.1007/s00702-009-0224-y  1
2009 Verwey NA, van der Flier WM, Blennow K, Clark C, Sokolow S, De Deyn PP, Galasko D, Hampel H, Hartmann T, Kapaki E, Lannfelt L, Mehta PD, Parnetti L, Petzold A, Pirttila T, et al. A worldwide multicentre comparison of assays for cerebrospinal fluid biomarkers in Alzheimer's disease. Annals of Clinical Biochemistry. 46: 235-40. PMID 19342441 DOI: 10.1258/Acb.2009.008232  1
2009 Lord A, Englund H, Söderberg L, Tucker S, Clausen F, Hillered L, Gordon M, Morgan D, Lannfelt L, Pettersson FE, Nilsson LN. Amyloid-beta protofibril levels correlate with spatial learning in Arctic Alzheimer's disease transgenic mice. The Febs Journal. 276: 995-1006. PMID 19215301 DOI: 10.1111/J.1742-4658.2008.06836.X  1
2009 Giedraitis V, Kilander L, Degerman-Gunnarsson M, Sundelöf J, Axelsson T, Syvänen AC, Lannfelt L, Glaser A. Genetic analysis of Alzheimer's disease in the Uppsala Longitudinal Study of Adult Men. Dementia and Geriatric Cognitive Disorders. 27: 59-68. PMID 19141999 DOI: 10.1159/000191203  1
2009 Näsström T, Wahlberg T, Karlsson M, Nikolajeff F, Lannfelt L, Ingelsson M, Bergström J. The lipid peroxidation metabolite 4-oxo-2-nonenal cross-links alpha-synuclein causing rapid formation of stable oligomers. Biochemical and Biophysical Research Communications. 378: 872-6. PMID 19070597 DOI: 10.1016/j.bbrc.2008.12.005  1
2009 Skoglund L, Brundin R, Olofsson T, Kalimo H, Ingvast S, Blom ES, Giedraitis V, Ingelsson M, Lannfelt L, Basun H, Glaser A. Frontotemporal dementia in a large Swedish family is caused by a progranulin null mutation. Neurogenetics. 10: 27-34. PMID 18855025 DOI: 10.1007/S10048-008-0155-Z  1
2009 Philipson O, Hammarström P, Nilsson KP, Portelius E, Olofsson T, Ingelsson M, Hyman BT, Blennow K, Lannfelt L, Kalimo H, Nilsson LN. A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice. Neurobiology of Aging. 30: 1393-405. PMID 18192084 DOI: 10.1016/J.Neurobiolaging.2007.11.022  1
2009 Wiltfang J, Lewczuk P, Riederer P, Grünblatt E, Hock C, Scheltens P, Hampel H, Vanderstichele H, Iqbal K, Galasko D, Lannfelt L, Otto M, Esselman H, Henkel AW, Kornhuber J, et al. Consensus paper of the WFSBP task force on biological markers of dementia: The role of CSF and blood analysis in the early and differential diagnosis of dementia | Trabalho de consenso de força-tarefa da WFSBP sobre marcadores biológicos das demências: Contribuição da análise do LCR e do sangue para o diagnóstico precoce e diferencial das demências Revista De Psiquiatria Clinica. 36: 1-16. DOI: 10.1590/S0101-60832009000700001  1
2008 Bertram L, Schjeide BM, Hooli B, Mullin K, Hiltunen M, Soininen H, Ingelsson M, Lannfelt L, Blacker D, Tanzi RE. No association between CALHM1 and Alzheimer's disease risk. Cell. 135: 993-4; author reply . PMID 19070563 DOI: 10.1016/J.Cell.2008.11.030  1
2008 Sundelöf J, Arnlöv J, Ingelsson E, Sundström J, Basu S, Zethelius B, Larsson A, Irizarry MC, Giedraitis V, Rönnemaa E, Degerman-Gunnarsson M, Hyman BT, Basun H, Kilander L, Lannfelt L. Serum cystatin C and the risk of Alzheimer disease in elderly men. Neurology. 71: 1072-9. PMID 18824671 DOI: 10.1212/01.wnl.0000326894.40353.93  1
2008 Lannfelt L, Blennow K, Zetterberg H, Batsman S, Ames D, Harrison J, Masters CL, Targum S, Bush AI, Murdoch R, Wilson J, Ritchie CW. Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial. The Lancet. Neurology. 7: 779-86. PMID 18672400 DOI: 10.1016/S1474-4422(08)70167-4  1
2008 O'Callaghan P, Sandwall E, Li JP, Yu H, Ravid R, Guan ZZ, van Kuppevelt TH, Nilsson LN, Ingelsson M, Hyman BT, Kalimo H, Lindahl U, Lannfelt L, Zhang X. Heparan sulfate accumulation with Abeta deposits in Alzheimer's disease and Tg2576 mice is contributed by glial cells. Brain Pathology (Zurich, Switzerland). 18: 548-61. PMID 18422760 DOI: 10.1111/J.1750-3639.2008.00152.X  1
2008 Basun H, Bogdanovic N, Ingelsson M, Almkvist O, Näslund J, Axelman K, Bird TD, Nochlin D, Schellenberg GD, Wahlund LO, Lannfelt L. Clinical and neuropathological features of the arctic APP gene mutation causing early-onset Alzheimer disease. Archives of Neurology. 65: 499-505. PMID 18413473 DOI: 10.1001/Archneur.65.4.499  1
2008 Rönnemaa E, Zethelius B, Sundelöf J, Sundström J, Degerman-Gunnarsson M, Berne C, Lannfelt L, Kilander L. Impaired insulin secretion increases the risk of Alzheimer disease. Neurology. 71: 1065-71. PMID 18401020 DOI: 10.1212/01.wnl.0000310646.32212.3a  1
2008 Sundelöf J, Giedraitis V, Irizarry MC, Sundström J, Ingelsson E, Rönnemaa E, Arnlöv J, Gunnarsson MD, Hyman BT, Basun H, Ingelsson M, Lannfelt L, Kilander L. Plasma beta amyloid and the risk of Alzheimer disease and dementia in elderly men: a prospective, population-based cohort study. Archives of Neurology. 65: 256-63. PMID 18268197 DOI: 10.1001/Archneurol.2007.57  1
2008 Blom ES, Holmans P, Arepalli S, Adighibe O, Hamshere ML, Gatz M, Pedersen NL, Bergem AL, Owen MJ, Hollingworth P, Goate A, Williams J, Lannfelt L, Hardy J, Wavrant-De Vrièze F, et al. Does APOE explain the linkage of Alzheimer's disease to chromosome 19q13? American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 778-83. PMID 18161859 DOI: 10.1002/Ajmg.B.30681  1
2008 Auro K, Kristiansson K, Zethelius B, Berne C, Lannfelt L, Taskinen MR, Jauhiainen M, Perola M, Peltonen L, Syvänen AC. USF1 gene variants contribute to metabolic traits in men in a longitudinal 32-year follow-up study. Diabetologia. 51: 464-72. PMID 18097648 DOI: 10.1007/s00125-007-0892-9  1
2008 Skoglund L, Viitanen M, Kalimo H, Lannfelt L, Jönhagen ME, Ingelsson M, Glaser A, Herva R. The tau S305S mutation causes frontotemporal dementia with parkinsonism. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 15: 156-61. PMID 18093153 DOI: 10.1111/J.1468-1331.2007.02017.X  1
2008 Blom ES, Viswanathan J, Kilander L, Helisalmi S, Soininen H, Lannfelt L, Ingelsson M, Glaser A, Hiltunen M. Low prevalence of APP duplications in Swedish and Finnish patients with early-onset Alzheimer's disease. European Journal of Human Genetics : Ejhg. 16: 171-5. PMID 18043715 DOI: 10.1038/sj.ejhg.5201966  1
2008 Engler H, Santillo AF, Wang SX, Lindau M, Savitcheva I, Nordberg A, Lannfelt L, LÃ¥ngström B, Kilander L. In vivo amyloid imaging with PET in frontotemporal dementia. European Journal of Nuclear Medicine and Molecular Imaging. 35: 100-6. PMID 17846768 DOI: 10.1007/S00259-007-0523-1  1
2008 Nase G, Helm PJ, Oguchi T, Nilsson LNG, Lannfelt L, Ottersen OP, Torp R. Local impact of perivascular plaques on cerebral blood flow dynamics in a transgenic mouse model of Alzheimer's disease Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6860. DOI: 10.1117/12.762739  1
2008 Philipson O, Lord A, Olofsson T, Ingelsson M, Lannfelt L, Kalimo H, Nilsson LNG. P1-097: The arctic Alzheimer mutation alters structure and composition of Aβ deposits Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.683  1
2008 Sundelöf JE, Ärnlöv J, Ingelsson E, Sundström J, Basu S, Zethelius B, Larsson A, Irizarry MC, Giedraitis V, Rönnemaa E, Degerman-Gunnarsson M, Hyman BT, Basun H, Kilander L, Lannfelt L. P4-108: Serum cystatin C and the risk of Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.2174  1
2008 Callaghan PO, Sandwall E, Li J, Yu H, Ravid R, Guan Z, Kuppevelt THv, Nilsson LNG, Ingelsson M, Hyman BT, Kalimo H, Lindahl U, Lannfelt L, Zhang X. P3-416: Aβ stimulation leads to elevated levels of heparan sulfate proteoglycans in glial cells Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1987  1
2008 Giedraitis V, Irizarry MC, Sundelöf J, Gunnarsson MD, Kilander L, Glaser A, Ingelsson M, Hyman BT, Basun H, Lannfelt L. P3-222: Genetic regulation of Aβ levels in human plasma Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1789  1
2008 Blom ES, Wang Y, Hansson A, Sommer W, Hyman BT, Heilig M, Lannfelt L, Nisson LNG, Ingelsson M. P3-205: Upregulation of genes in the Wnt pathway in tg-ArcSwe mice and Alzheimer's disease brain Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1772  1
2008 Ingelsson M, Blom E, Zetterberg H, Fukumoto H, Hyman BT, Irizarry MC, Blennow K, Wahlund L, Lannfelt L. P3-076: CSF Tau levels and APOEϵ4 carriership predict the progression of mild cognitive impairment to Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1640  1
2008 Gabelle A, Roche S, Gény C, Portet F, Touchon J, Lehmann S, Meyer GD, Shapiro F, Vanderstichele H, Vanmechelen E, Engelborghs S, Deyn PPD, Shaw L, Trojanowski J, Nestor SM, ... ... Lannfelt L, et al. 1st Conference Clinical Trials on Alzheimer’s Disease September 17-18-19, 2008 School of Medecine Montpellier, France Journal of Nutrition Health & Aging. 12: 531-543. DOI: 10.1007/Bf02983205  1
2007 Giedraitis V, Sundelöf J, Irizarry MC, GÃ¥revik N, Hyman BT, Wahlund LO, Ingelsson M, Lannfelt L. The normal equilibrium between CSF and plasma amyloid beta levels is disrupted in Alzheimer's disease. Neuroscience Letters. 427: 127-31. PMID 17936506 DOI: 10.1016/J.Neulet.2007.09.023  1
2007 Englund H, Annerén G, Gustafsson J, Wester U, Wiltfang J, Lannfelt L, Blennow K, Höglund K. Increase in beta-amyloid levels in cerebrospinal fluid of children with Down syndrome. Dementia and Geriatric Cognitive Disorders. 24: 369-74. PMID 17914261 DOI: 10.1159/000109215  1
2007 Sahlin C, Pettersson FE, Nilsson LN, Lannfelt L, Johansson AS. Docosahexaenoic acid stimulates non-amyloidogenic APP processing resulting in reduced Abeta levels in cellular models of Alzheimer's disease. The European Journal of Neuroscience. 26: 882-9. PMID 17714184 DOI: 10.1111/j.1460-9568.2007.05719.x  1
2007 Degerman Gunnarsson M, Kilander L, Basun H, Lannfelt L. Reduction of phosphorylated tau during memantine treatment of Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 24: 247-52. PMID 17700020 DOI: 10.1159/000107099  1
2007 Nilsson KP, Aslund A, Berg I, Nyström S, Konradsson P, Herland A, Inganäs O, Stabo-Eeg F, Lindgren M, Westermark GT, Lannfelt L, Nilsson LN, Hammarström P. Imaging distinct conformational states of amyloid-beta fibrils in Alzheimer's disease using novel luminescent probes. Acs Chemical Biology. 2: 553-60. PMID 17672509 DOI: 10.1021/Cb700116U  1
2007 Warensjö E, Ingelsson E, Lundmark P, Lannfelt L, Syvänen AC, Vessby B, Risérus U. Polymorphisms in the SCD1 gene: associations with body fat distribution and insulin sensitivity. Obesity (Silver Spring, Md.). 15: 1732-40. PMID 17636091 DOI: 10.1038/oby.2007.206  1
2007 Englund H, Sehlin D, Johansson AS, Nilsson LN, Gellerfors P, Paulie S, Lannfelt L, Pettersson FE. Sensitive ELISA detection of amyloid-beta protofibrils in biological samples. Journal of Neurochemistry. 103: 334-45. PMID 17623042 DOI: 10.1111/j.1471-4159.2007.04759.x  1
2007 Blennow K, Zetterberg H, Minthon L, Lannfelt L, Strid S, Annas P, Basun H, Andreasen N. Longitudinal stability of CSF biomarkers in Alzheimer's disease. Neuroscience Letters. 419: 18-22. PMID 17482358 DOI: 10.1016/j.neulet.2007.03.064  1
2007 Sahlin C, Lord A, Magnusson K, Englund H, Almeida CG, Greengard P, Nyberg F, Gouras GK, Lannfelt L, Nilsson LN. The Arctic Alzheimer mutation favors intracellular amyloid-beta production by making amyloid precursor protein less available to alpha-secretase. Journal of Neurochemistry. 101: 854-62. PMID 17448150 DOI: 10.1111/J.1471-4159.2006.04443.X  1
2007 Nilsson LN, Lannfelt L, Basun H, Nordberg A, Winblad B. [Don't underestimate the value of transgenic animal models of Alzheimer disease]. Lã¤Kartidningen. 104: 798-9; discussion 79. PMID 17432800  1
2007 Wohlin M, Sundström J, Lannfelt L, Axelsson T, Syvänen AC, Andrén B, Basu S, Lind L. Apolipoprotein E epsilon4 genotype is independently associated with increased intima-media thickness in a recessive pattern. Lipids. 42: 451-6. PMID 17426996 DOI: 10.1007/s11745-007-3045-5  1
2007 Johansson AS, Bergquist J, Volbracht C, Päiviö A, Leist M, Lannfelt L, Westlind-Danielsson A. Attenuated amyloid-beta aggregation and neurotoxicity owing to methionine oxidation. Neuroreport. 18: 559-63. PMID 17413657 DOI: 10.1097/WNR.0b013e3280b07c21  1
2007 Wollmer MA, Sleegers K, Ingelsson M, Zekanowski C, Brouwers N, Maruszak A, Brunner F, Huynh KD, Kilander L, Brundin RM, Hedlund M, Giedraitis V, Glaser A, Engelborghs S, De Deyn PP, ... ... Lannfelt L, et al. Association study of cholesterol-related genes in Alzheimer's disease. Neurogenetics. 8: 179-88. PMID 17387528 DOI: 10.1007/S10048-007-0087-Z  1
2007 Johansson AS, Garlind A, Berglind-Dehlin F, Karlsson G, Edwards K, Gellerfors P, Ekholm-Pettersson F, Palmblad J, Lannfelt L. Docosahexaenoic acid stabilizes soluble amyloid-beta protofibrils and sustains amyloid-beta-induced neurotoxicity in vitro. The Febs Journal. 274: 990-1000. PMID 17227385 DOI: 10.1111/j.1742-4658.2007.05647.x  1
2006 Giedraitis V, Hedlund M, Skoglund L, Blom E, Ingvast S, Brundin R, Lannfelt L, Glaser A. New Alzheimer's disease locus on chromosome 8. Journal of Medical Genetics. 43: 931-5. PMID 16825432 DOI: 10.1136/jmg.2006.043000  1
2006 Johansson AS, Berglind-Dehlin F, Karlsson G, Edwards K, Gellerfors P, Lannfelt L. Physiochemical characterization of the Alzheimer's disease-related peptides A beta 1-42Arctic and A beta 1-42wt. The Febs Journal. 273: 2618-30. PMID 16817891 DOI: 10.1111/j.1742-4658.2006.05263.x  1
2006 Ingelsson M, Ramasamy K, Cantuti-Castelvetri I, Skoglund L, Matsui T, Orne J, Kowa H, Raju S, Vanderburg CR, Augustinack JC, de Silva R, Lees AJ, Lannfelt L, Growdon JH, Frosch MP, et al. No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer's disease brain. Acta Neuropathologica. 112: 439-49. PMID 16802167 DOI: 10.1007/S00401-006-0095-3  1
2006 Murphy EJ, Huang HM, Cowburn RF, Lannfelt L, Gibson GE. Phospholipid mass is increased in fibroblasts bearing the Swedish amyloid precursor mutation. Brain Research Bulletin. 69: 79-85. PMID 16464688 DOI: 10.1016/j.brainresbull.2005.10.012  1
2006 Lord A, Kalimo H, Eckman C, Zhang XQ, Lannfelt L, Nilsson LN. The Arctic Alzheimer mutation facilitates early intraneuronal Abeta aggregation and senile plaque formation in transgenic mice. Neurobiology of Aging. 27: 67-77. PMID 16298242 DOI: 10.1016/J.Neurobiolaging.2004.12.007  1
2006 Ingelsson M, Blom E, Fukumoto H, Zetterberg H, Gårevik N, Blennow K, Hyman BT, Lannfelt L, Wahlund L, Irizarry MC. P2-160: Csf Aβ and tau levels in Alzheimer’s disease and mild cognitive impairment Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.998  1
2006 Callaghan PO, Yu H, Nilsson LNG, Ingelsson M, Hyman BT, Li J, Lindahl U, Lannfelt L, Zhang X. P1-387: Comparative analysis of heparan sulfate co-localization with Aβ40 and Aβ42 in different Aβ deposits of APP transgenic mice and Alzheimer’s disease patients Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.765  1
2006 Philipsson O, Portelius E, Olofsson T, Kalimo H, Blennow K, Lannfelt L, Nilsson LNG. P1-038: Immunohistochemical and biochemical analyses of Aβ deposits in Tg-APP-ArcSwe and Tg-APP-Swe transgenic mouse brain Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.413  1
2006 Blom ES, Sommer WH, Hansson AC, Heilig M, Ubaldi M, Lourdusamy AA, Lannfelt L, Ingelsson M, Nilsson LNG. P1-030: Analysis of gene expression in brains of tg-APP-ArcSwe mice, a model for Alzheimer’s disease Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.405  1
2006 Stenh C, Lord A, Magnusson K, Englund H, Almeida CG, Greengard P, Nyberg F, Gouras GK, Lannfelt L, Nilsson LNG. AbstractPoster presentation: Wednesday posterP4-041: The Arctic Alzheimer mutation favors Aβ production by making APP less available to α-secretase at the cell surface Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1779  1
2006 Skoglund L, Kalimo H, Herva R, Ingelsson M, Lannfelt L, Glaser A, Viitanen M. P3-150: Frontotemporal dementia and parkinsonism: A new phenotype of the tau S305S mutation Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1418  1
2006 Engler HW, Louhija UM, Savitcheva I, Olofsson T, Kalimo H, Lannfelt L, Långström BR. AbstractPoster presentation: Monday posterP2-273: PET-imaging of amyloid depositions and astrocytosis in severe ad and histopathological correlations in one patient Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1112  1
2006 Bogdanovic N, Arendt T, Lannfelt L, Basun H, Winblad B, Näslund J, Härtig W. O1-01-05 Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.038  1
2005 Selle H, Lamerz J, Buerger K, Dessauer A, Hager K, Hampel H, Karl J, Kellmann M, Lannfelt L, Louhija J, Riepe M, Rollinger W, Tumani H, Schrader M, Zucht HD. Identification of novel biomarker candidates by differential peptidomics analysis of cerebrospinal fluid in Alzheimer's disease. Combinatorial Chemistry & High Throughput Screening. 8: 801-6. PMID 16464167 DOI: 10.2174/138620705774962391  1
2005 Ingelsson M, Nilsson L, Basun H, Aquilonius SM, Lannfelt L. [Conformationally altered proteins cause neurodegenerative diseases]. Lã¤Kartidningen. 102: 3542-3, 3545-6, 3549. PMID 16408392  1
2005 Wiltfang J, Lewczuk P, Riederer P, Grünblatt E, Hock C, Scheltens P, Hampel H, Vanderstichele H, Iqbal K, Galasko D, Lannfelt L, Otto M, Esselmann H, Henkel AW, Kornhuber J, et al. Consensus paper of the WFSBP Task Force on Biological Markers of Dementia: the role of CSF and blood analysis in the early and differential diagnosis of dementia. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 6: 69-84. PMID 16156480 DOI: 10.1080/15622970510029786  1
2005 Stenh C, Englund H, Lord A, Johansson AS, Almeida CG, Gellerfors P, Greengard P, Gouras GK, Lannfelt L, Nilsson LN. Amyloid-beta oligomers are inefficiently measured by enzyme-linked immunosorbent assay. Annals of Neurology. 58: 147-50. PMID 15984012 DOI: 10.1002/Ana.20524  1
2005 Flood F, Murphy S, Cowburn RF, Lannfelt L, Walker B, Johnston JA. Proteasome-mediated effects on amyloid precursor protein processing at the gamma-secretase site. The Biochemical Journal. 385: 545-50. PMID 15473868 DOI: 10.1042/BJ20041145  1
2004 Froelich-Fabre S, Skoglund L, Ostojic J, Kilander L, Lindau M, Glaser A, Basun H, Lannfelt L. Clinical and molecular aspects of frontotemporal dementia. Neuro-Degenerative Diseases. 1: 218-24. PMID 16908993 DOI: 10.1159/000080989  1
2004 Ostojic J, Elfgren C, Passant U, Nilsson K, Gustafson L, Lannfelt L, Froelich Fabre S. The tau R406W mutation causes progressive presenile dementia with bitemporal atrophy. Dementia and Geriatric Cognitive Disorders. 17: 298-301. PMID 15178940 DOI: 10.1159/000077158  1
2004 Passant U, Ostojic J, Froelich Fabre S, Gustafson L, Lannfelt L, Larsson EM, Nilsson K, Rosén I, Elfgren C. Familial presenile dementia with bitemporal atrophy. Dementia and Geriatric Cognitive Disorders. 17: 287-92. PMID 15178938 DOI: 10.1159/000077156  1
2004 Johnson J, Ostojic J, Lannfelt L, Glaser A, Basun H, Rogaeva E, Kawarai T, Bruni A, St George Hyslop PH, Goate A, Pastor P, Chakraverty S, Norton J, Morris JC, Hardy J, et al. No evidence for tau duplications in frontal temporal dementia families showing genetic linkage to the tau locus in which tau mutations have not been found. Neuroscience Letters. 363: 99-101. PMID 15172093 DOI: 10.1016/J.Neulet.2004.03.070  1
2004 Päiviö A, Jarvet J, Gräslund A, Lannfelt L, Westlind-Danielsson A. Unique physicochemical profile of beta-amyloid peptide variant Abeta1-40E22G protofibrils: conceivable neuropathogen in arctic mutant carriers. Journal of Molecular Biology. 339: 145-59. PMID 15123427 DOI: 10.1016/j.jmb.2004.03.028  1
2004 Bergman A, Hansson EM, Pursglove SE, Farmery MR, Lannfelt L, Lendahl U, Lundkvist J, Näslund J. Pen-2 is sequestered in the endoplasmic reticulum and subjected to ubiquitylation and proteasome-mediated degradation in the absence of presenilin. The Journal of Biological Chemistry. 279: 16744-53. PMID 14724271 DOI: 10.1074/jbc.M313999200  1
2004 Braungart E, Gerlach M, Riederer P, Baumeister R, Hoener MC, Silva OABdCe, Vieira SI, Silva EFdCe, Froelich-Fabre S, Skoglund L, Ostojic J, Kilander L, Lindau M, Rebelo S, Hartmann D, ... ... Lannfelt L, et al. DIADEM / Participants Directory Neurodegenerative Diseases. 1: 243-244. DOI: 10.1159/000082213  1
2004 Moore P, Dennis K, DeVita C, Grossman M, Lebert F, Stekke W, Hasenbroekx C, Pasquier F, Johnson JK, Vogt BA, Kim R, Cotman CW, Head E, Comstock H, Pickering-Brown S, ... ... Lannfelt L, et al. Contents Vol. 17, 2004 Dementia and Geriatric Cognitive Disorders. 17: 387-389. DOI: 10.1159/000078837  1
2004 Moore P, Dennis K, DeVita C, Grossman M, Lebert F, Stekke W, Hasenbroekx C, Pasquier F, Johnson JK, Vogt BA, Kim R, Cotman CW, Head E, Comstock H, Pickering-Brown S, ... ... Lannfelt L, et al. Subject Index Vol. 17, 2004 Dementia and Geriatric Cognitive Disorders. 17: 384-385. DOI: 10.1159/000078836  1
2004 Blom E, Holmans P, Arepalli S, Adighibe O, Hardy J, Lannfelt L, Glaser A, Vrièze FW. P4-070 Is APOE exclusively responsible for the AD linkage peak on chromosome 19? Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81628-2  1
2003 Axelman K, Lannfelt L, Almkvist O, Carlsson M. Life situation, coping and quality of life in people with high and low risk of developing Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 16: 220-8. PMID 14512717 DOI: 10.1159/000072806  1
2003 Olsson A, Höglund K, Sjögren M, Andreasen N, Minthon L, Lannfelt L, Buerger K, Möller HJ, Hampel H, Davidsson P, Blennow K. Measurement of alpha- and beta-secretase cleaved amyloid precursor protein in cerebrospinal fluid from Alzheimer patients. Experimental Neurology. 183: 74-80. PMID 12957490 DOI: 10.1016/S0014-4886(03)00027-X  1
2003 Froelich Fabre S, Axelman P, Almkvist A, Basun H, Lannfelt L. Extended investigation of tau and mutation screening of other candidate genes on chromosome 17q21 in a Swedish FTDP-17 family. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 121: 112-8. PMID 12898585 DOI: 10.1002/ajmg.b.20067  1
2003 Bergman A, Religa D, Karlström H, Laudon H, Winblad B, Lannfelt L, Lundkvist J, Näslund J. APP intracellular domain formation and unaltered signaling in the presence of familial Alzheimer's disease mutations. Experimental Cell Research. 287: 1-9. PMID 12799176 DOI: 10.1016/S0014-4827(03)00117-4  1
2003 Ostojic J, Axelman K, Lannfelt L, Froelich-Fabre S. No evidence of linkage to chromosome 9q21-22 in a Swedish family with frontotemporal dementia and amyotrophic lateral sclerosis. Neuroscience Letters. 340: 245-7. PMID 12672552 DOI: 10.1016/S0304-3940(03)00126-5  1
2003 Almkvist O, Axelman K, Basun H, Jensen M, Viitanen M, Wahlund LO, Lannfelt L. Clinical findings in nondemented mutation carriers predisposed to Alzheimer's disease: a model of mild cognitive impairment. Acta Neurologica Scandinavica. Supplementum. 179: 77-82. PMID 12603253 DOI: 10.1034/J.1600-0404.107.S179.11.X  1
2003 Tai CT, Mårdh E, Borch K, Mårdh S, Kalbe E, Calabrese P, Schwalen S, Kessler J, Wallin A, Sjögren M, Blennow K, Davidsson P, Forti P, Maioli F, Arnone G, ... ... Lannfelt L, et al. Contents Vol. 16, 2003 Dementia and Geriatric Cognitive Disorders. 16: 305-306. DOI: 10.1159/000073699  1
2003 Tai CT, Mårdh E, Borch K, Mårdh S, Kalbe E, Calabrese P, Schwalen S, Kessler J, Wallin A, Sjögren M, Blennow K, Davidsson P, Forti P, Maioli F, Arnone G, ... ... Lannfelt L, et al. Subject Index Vol. 16, 2003 Dementia and Geriatric Cognitive Disorders. 16: 303-304. DOI: 10.1159/000073698  1
2002 Almkvist O, Axelman K, Basun H, Wahlund LO, Lannfelt L. Conversion from preclinical to dinical stage of Alzheimer's disease as shown by decline of cognitive function in carriers of the Swedish APP-mutation. Journal of Neural Transmission. Supplementum. 117-25. PMID 12456057 DOI: 10.1007/978-3-7091-6139-5_12  1
2002 Stenh C, Nilsberth C, Hammarbäck J, Engvall B, Näslund J, Lannfelt L. The Arctic mutation interferes with processing of the amyloid precursor protein. Neuroreport. 13: 1857-60. PMID 12395079 DOI: 10.1097/00001756-200210280-00005  1
2002 Basun H, Nilsberth C, Eckman C, Lannfelt L, Younkin S. Plasma levels of Abeta42 and Abeta40 in Alzheimer patients during treatment with the acetylcholinesterase inhibitor tacrine. Dementia and Geriatric Cognitive Disorders. 14: 156-60. PMID 12218259 DOI: 10.1159/000063605  1
2002 Bogdanovic N, Corder E, Lannfelt L, Winblad B. APOE polymorphism and clinical duration determine regional neuropathology in Swedish APP(670, 671) mutation carriers: implications for late-onset Alzheimer's disease. Journal of Cellular and Molecular Medicine. 6: 199-214. PMID 12169205 DOI: 10.1111/J.1582-4934.2002.Tb00187.X  1
2002 Sennvik K, Nilsberth C, Stenh C, Lannfelt L, Benedikz E. The Arctic Alzheimer mutation enhances sensitivity to toxic stress in human neuroblastoma cells. Neuroscience Letters. 326: 51-5. PMID 12052536 DOI: 10.1016/S0304-3940(02)00305-1  1
2002 Masterman T, Zhang Z, Hellgren D, Salter H, Anvret M, Lilius L, Lannfelt L, Hillert J. APOE genotypes and disease severity in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 8: 98-103. PMID 11990879 DOI: 10.1191/1352458502Ms787Oa  1
2001 Forsell C, Enmark E, Axelman K, Blomberg M, Wahlund LO, Gustafsson JA, Lannfelt L. Investigations of a CA repeat in the oestrogen receptor beta gene in patients with Alzheimer's disease. European Journal of Human Genetics : Ejhg. 9: 802-4. PMID 11781694 DOI: 10.1038/Sj.Ejhg.5200714  1
2001 Bogdanovic N, Bretillon L, Lund EG, Diczfalusy U, Lannfelt L, Winblad B, Russell DW, Björkhem I. On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells. Neuroscience Letters. 314: 45-8. PMID 11698143 DOI: 10.1016/S0304-3940(01)02277-7  1
2001 Nilsberth C, Westlind-Danielsson A, Eckman CB, Condron MM, Axelman K, Forsell C, Stenh C, Luthman J, Teplow DB, Younkin SG, Näslund J, Lannfelt L. The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation. Nature Neuroscience. 4: 887-93. PMID 11528419 DOI: 10.1038/Nn0901-887  1
2001 Davidsson P, Bogdanovic N, Lannfelt L, Blennow K. Reduced expression of amyloid precursor protein, presenilin-1 and rab3a in cortical brain regions in Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 12: 243-50. PMID 11351135 DOI: 10.1159/000051266  1
2001 Ingelson M, Fabre SF, Lilius L, Andersen C, Viitanen M, Almkvist O, Wahlund LO, Lannfelt L. Increased risk for frontotemporal dementia through interaction between tau polymorphisms and apolipoprotein E epsilon4. Neuroreport. 12: 905-9. PMID 11303757 DOI: 10.1097/00001756-200104170-00008  1
2001 Fabre SF, Forsell C, Viitanen M, Sjögren M, Wallin A, Blennow K, Blomberg M, Andersen C, Wahlund LO, Lannfelt L. Clinic-based cases with frontotemporal dementia show increased cerebrospinal fluid tau and high apolipoprotein E epsilon4 frequency, but no tau gene mutations. Experimental Neurology. 168: 413-8. PMID 11259129 DOI: 10.1006/Exnr.2000.7613  1
2001 Blomberg M, Jensen M, Basun H, Lannfelt L, Wahlund LO. Cerebrospinal fluid tau levels increase with age in healthy individuals. Dementia and Geriatric Cognitive Disorders. 12: 127-32. PMID 11173885 DOI: 10.1159/000051246  1
2001 Guo Z, Fratiglioni L, Viitanen M, Lannfelt L, Basun H, Fastbom J, Winblad B. Apolipoprotein E genotypes and the incidence of Alzheimer's disease among persons aged 75 years and older: variation by use of antihypertensive medication? American Journal of Epidemiology. 153: 225-31. PMID 11157409 DOI: 10.1093/Aje/153.3.225  1
2000 Andersen C, Froelich Fabre S, Ostberg P, Lannfelt L, Wahlund L. Tau protein in cerebrospinal fluid from semantic dementia patients. Neuroscience Letters. 294: 155-8. PMID 11072138 DOI: 10.1016/S0304-3940(00)01566-4  1
2000 Lannfelt L, Nordstedt C. Genetics of Alzheimer's disease--routes to the pathophysiology. Journal of Neural Transmission. Supplementum. 59: 155-61. PMID 10961427 DOI: 10.1007/978-3-7091-6781-6_17  1
2000 Jensen M, Hartmann T, Engvall B, Wang R, Uljon SN, Sennvik K, Näslund J, Muehlhauser F, Nordstedt C, Beyreuther K, Lannfelt L. Quantification of Alzheimer amyloid beta peptides ending at residues 40 and 42 by novel ELISA systems. Molecular Medicine (Cambridge, Mass.). 6: 291-302. PMID 10949910 DOI: 10.1007/Bf03401938  1
2000 Corder EH, Basun H, Fratiglioni L, Guo Z, Lannfelt L, Viitanen M, Corder LS, Manton KG, Winblad B. Inherited frailty. ApoE alleles determine survival after a diagnosis of heart disease or stroke at ages 85+. Annals of the New York Academy of Sciences. 908: 295-8. PMID 10911969 DOI: 10.1111/J.1749-6632.2000.Tb06657.X  1
2000 Russo C, Schettini G, Saido TC, Hulette C, Lippa C, Lannfelt L, Ghetti B, Gambetti P, Tabaton M, Teller JK. Presenilin-1 mutations in Alzheimer's disease. Nature. 405: 531-2. PMID 10850703 DOI: 10.1038/35014735  1
2000 Ito C, Morisset S, Krebs MO, Olié JP, Lôo H, Poirier MF, Lannfelt L, Schwartz JC, Arrang JM. Histamine H2 receptor gene variants: lack of association with schizophrenia. Molecular Psychiatry. 5: 159-64. PMID 10822343  1
2000 Mattila KM, Axelman K, Rinne JO, Blomberg M, Lehtimäki T, Laippala P, Röyttä M, Viitanen M, Wahlund L, Winblad B, Lannfelt L. Interaction between estrogen receptor 1 and the epsilon4 allele of apolipoprotein E increases the risk of familial Alzheimer's disease in women. Neuroscience Letters. 282: 45-8. PMID 10713392 DOI: 10.1016/S0304-3940(00)00849-1  1
2000 Andersen C, Jensen M, Lannfelt L, Lindau M, Wahlund LO. Amyloid Abeta40 CSF concentrations correlate to frontal lobe atrophy in frontotemporal dementia. Neuroreport. 11: 287-90. PMID 10674472  1
2000 Johnston JA, Jensen M, Lannfelt L, Walker B, Williams C. Inhibition of Prolylendopeptidase does not affect γ-secretase processing of amyloid precursor protein Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A033C  1
2000 Engvall B, Nšslund J, Lannfelt L, Nordstedt C. Detection of amyloid β-peptide — methodological considerations Neurobiology of Aging. 21: 237. DOI: 10.1016/S0197-4580(00)83405-3  1
1999 Johnston JA, Jensen M, Lannfelt L, Walker B, Williams CH. Inhibition of prolylendopeptidase does not affect gamma-secretase processing of amyloid precursor protein in a human neuroblastoma cell line. Neuroscience Letters. 277: 33-6. PMID 10643891 DOI: 10.1016/S0304-3940(99)00834-4  1
1999 Lilius L, Froelich Fabre S, Basun H, Forsell C, Axelman K, Mattila K, Andreadis A, Viitanen M, Winblad B, Fratiglioni L, Lannfelt L. Tau gene polymorphisms and apolipoprotein E epsilon4 may interact to increase risk for Alzheimer's disease. Neuroscience Letters. 277: 29-32. PMID 10643890 DOI: 10.1016/S0304-3940(99)00833-2  1
1999 Wahlund LO, Basun H, Almkvist O, Julin P, Axelman K, Shigeta M, Jelic V, Nordberg A, Lannfelt L. A follow-up study of the family with the Swedish APP 670/671 Alzheimer's disease mutation. Dementia and Geriatric Cognitive Disorders. 10: 526-33. PMID 10559570 DOI: 10.1159/000017200  1
1999 Mustafa A, Lannfelt L, Lilius L, Islam A, Winblad B, Adem A. Decreased plasma insulin-like growth factor-I level in familial Alzheimer's disease patients carrying the Swedish APP 670/671 mutation. Dementia and Geriatric Cognitive Disorders. 10: 446-51. PMID 10559558 DOI: 10.1159/000017188  1
1999 Ingelson M, Blomberg M, Benedikz E, Wahlund LO, Karlsson E, Vanmechelen E, Lannfelt L. Tau immunoreactivity detected in human plasma, but no obvious increase in dementia. Dementia and Geriatric Cognitive Disorders. 10: 442-5. PMID 10559557 DOI: 10.1159/000017187  1
1999 Savioz A, Leuba G, Forsell C, Lilius L, Rossier C, Saini K, Bouras C, Lannfelt L. No detected mutations in the genes for the amyloid precursor protein and presenilins 1 and 2 in a swiss early-onset Alzheimer's disease family with a dominant mode of inheritance. Dementia and Geriatric Cognitive Disorders. 10: 431-6. PMID 10559555 DOI: 10.1159/000017185  1
1999 Nilsberth C, Luthman J, Lannfelt L, Schultzberg M. Expression of presenilin 1 mRNA in rat peripheral organs and brain. The Histochemical Journal. 31: 515-23. PMID 10507458 DOI: 10.1023/A:1003887922777  1
1999 Froelich S, Houlden H, Rizzu P, Chakraverty S, Baker M, Kwon J, Nowotny P, Isaacs A, Nowotny V, Wauters E, van Baren MJ, Oostra BA, Hardy J, Lannfelt L, Goate A, et al. Construction of a detailed physical and transcript map of the FTDP-17 candidate region on chromosome 17q21. Genomics. 60: 129-36. PMID 10486204 DOI: 10.1006/Geno.1999.5892  1
1999 Wahlund LO, Julin P, Lannfelt L, Lindqvist J, Svensson L. Inheritance of the ApoE epsilon4 allele increases the rate of brain atrophy in dementia patients. Dementia and Geriatric Cognitive Disorders. 10: 262-8. PMID 10364643 DOI: 10.1159/000017130  1
1999 Kostulas K, Huang WX, Crisby M, Jin YP, He B, Lannfelt L, Eggertsen G, Kostulas V, Hillert J. An angiotensin-converting enzyme gene polymorphism suggests a genetic distinction between ischaemic stroke and carotid stenosis. European Journal of Clinical Investigation. 29: 478-83. PMID 10354208  1
1999 Kowalska A, Forsell C, Florczak J, Pruchnik-WoliÅ„ska D, Modestowicz R, Paprzycki W, Wender M, Lannfelt L. A Polish pedigree with Alzheimer's disease determined by a novel mutation in exon 12 of the presenilin 1 gene: clinical and molecular characterization. Folia Neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences. 37: 57-61. PMID 10337065  1
1999 Sheu KF, Brown AM, Kristal BS, Kalaria RN, Lilius L, Lannfelt L, Blass JP. A DLST genotype associated with reduced risk for Alzheimer's disease. Neurology. 52: 1505-7. PMID 10227647 DOI: 10.1212/Wnl.52.7.1505  1
1999 Jensen M, Schröder J, Blomberg M, Engvall B, Pantel J, Ida N, Basun H, Wahlund LO, Werle E, Jauss M, Beyreuther K, Lannfelt L, Hartmann T. Cerebrospinal fluid A beta42 is increased early in sporadic Alzheimer's disease and declines with disease progression. Annals of Neurology. 45: 504-11. PMID 10211475 DOI: 10.1002/1531-8249(199904)45:4<504::Aid-Ana12>3.0.Co;2-9  1
1999 Vestling M, Cedazo-Mínguez A, Adem A, Wiehager B, Racchi M, Lannfelt L, Cowburn RF. Protein kinase C and amyloid precursor protein processing in skin fibroblasts from sporadic and familial Alzheimer's disease cases. Biochimica Et Biophysica Acta. 1453: 341-50. PMID 10101252 DOI: 10.1016/S0925-4439(99)00003-4  1
1999 Marutle A, Warpman U, Bogdanovic N, Lannfelt L, Nordberg A. Neuronal nicotinic receptor deficits in Alzheimer patients with the Swedish amyloid precursor protein 670/671 mutation. Journal of Neurochemistry. 72: 1161-9. PMID 10037489 DOI: 10.1046/J.1471-4159.2000.0721161.X  1
1999 Bronge L, Fernaeus SE, Blomberg M, Ingelson M, Lannfelt L, Isberg B, Wahlund LO. White matter lesions in Alzheimer patients are influenced by apolipoprotein E genotype. Dementia and Geriatric Cognitive Disorders. 10: 89-96. PMID 10026381 DOI: 10.1159/000017107  1
1999 Nishimura M, Yu G, Levesque G, Zhang DM, Ruel L, Chen F, Milman P, Holmes E, Liang Y, Kawarai T, Jo E, Supala A, Rogaeva E, Xu DM, Janus C, ... ... Lannfelt L, et al. Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex. Nature Medicine. 5: 164-9. PMID 9930863 DOI: 10.1038/5526  1
1999 Sheu KF, Brown AM, Haroutunian V, Kristal BS, Thaler H, Lesser M, Kalaria RN, Relkin NR, Mohs RC, Lilius L, Lannfelt L, Blass JP. Modulation by DLST of the genetic risk of Alzheimer's disease in a very elderly population. Annals of Neurology. 45: 48-53. PMID 9894876 DOI: 10.1002/1531-8249(199901)45:1<48::Aid-Art9>3.0.Co;2-V  1
1999 Axelman K, Basun H, Lannfelt L. Apolipoprotein E and alpha1-antichymotrypsin genotypes and age of onset of familial Alzheimer's disease. Dementia and Geriatric Cognitive Disorders. 10: 1-5. PMID 9844031  1
1999 Ji Y, Urakami K, Adachi Y, Nakashima K, Herholz K, Nordberg A, Salmon E, Perani D, Kessler J, Mielke R, Halber M, Jelic V, Almkvist O, Collette F, Alberoni M, ... ... Lannfelt L, ... ... Lannfelt L, et al. Contents Vol. 10, 1999 Dementia and Geriatric Cognitive Disorders. 10: 553-555. DOI: 10.1159/000017205  1
1999 Ji Y, Urakami K, Adachi Y, Nakashima K, Herholz K, Nordberg A, Salmon E, Perani D, Kessler J, Mielke R, Halber M, Jelic V, Almkvist O, Collette F, Alberoni M, ... ... Lannfelt L, ... ... Lannfelt L, et al. Subject Index Vol. 10, 1999 Dementia and Geriatric Cognitive Disorders. 10: 551-552. DOI: 10.1159/000017204  1
1998 Mattila KM, Forsell C, Pirttilä T, Rinne JO, Lehtimäki T, Röyttä M, Lilius L, Eerola A, St George-Hyslop PH, Frey H, Lannfelt L. The Glu318Gly mutation of the presenilin-1 gene does not necessarily cause Alzheimer's disease. Annals of Neurology. 44: 965-7. PMID 9851443 DOI: 10.1002/Ana.410440617  1
1998 Almkvist O, Basun H, Bäckman L, Herlitz A, Lannfelt L, Small B, Viitanen M, Wahlund LO, Winblad B. Mild cognitive impairment--an early stage of Alzheimer's disease? Journal of Neural Transmission. Supplementum. 54: 21-9. PMID 9850912 DOI: 10.1007/978-3-7091-7508-8_3  1
1998 Corder EH, Lannfelt L, Bogdanovic N, Fratiglioni L, Mori H. The role of APOE polymorphisms in late-onset dementias. Cellular and Molecular Life Sciences : Cmls. 54: 928-34. PMID 9791536 DOI: 10.1007/S000180050223  1
1998 Corder E, Lannfelt L, Mulder M. Apolipoprotein E and herpes simplex virus 1 in Alzheimer's disease. Lancet. 352: 1312-3. PMID 9788486 DOI: 10.1016/S0140-6736(05)70525-0  1
1998 Gibson GE, Zhang H, Sheu KF, Bogdanovich N, Lindsay JG, Lannfelt L, Vestling M, Cowburn RF. Alpha-ketoglutarate dehydrogenase in Alzheimer brains bearing the APP670/671 mutation. Annals of Neurology. 44: 676-81. PMID 9778267 DOI: 10.1002/Ana.410440414  1
1998 Yamada H, Dahl ML, Lannfelt L, Viitanen M, Winblad B, Sjöqvist F. CYP2D6 and CYP2C19 genotypes in an elderly Swedish population. European Journal of Clinical Pharmacology. 54: 479-81. PMID 9776439 DOI: 10.1007/S002280050497  1
1998 Yamada H, Dahl ML, Viitanen M, Winblad B, Sjöqvist F, Lannfelt L. No association between familial Alzheimer disease and cytochrome P450 polymorphisms. Alzheimer Disease and Associated Disorders. 12: 204-7. PMID 9772024 DOI: 10.1097/00002093-199809000-00013  1
1998 Corder EH, Robertson K, Lannfelt L, Bogdanovic N, Eggertsen G, Wilkins J, Hall C. HIV-infected subjects with the E4 allele for APOE have excess dementia and peripheral neuropathy. Nature Medicine. 4: 1182-4. PMID 9771753 DOI: 10.1038/2677  1
1998 Reznik-Wolf H, Machado J, Haroutunian V, DeMarco L, Walter GF, Goldman B, Davidson M, Johnston JA, Lannfelt L, Dani SU, Friedman E. Somatic mutation analysis of the APP and Presenilin 1 and 2 genes in Alzheimer's disease brains. Journal of Neurogenetics. 12: 55-65. PMID 9666901 DOI: 10.3109/01677069809108555  1
1998 Forsell Y, Basun H, Corder EH, Lannfelt L, Winblad B. Psychotic symptoms and apolipoprotein E genotypes in an elderly population. Biological Psychiatry. 44: 139-40. PMID 9646896 DOI: 10.1016/S0006-3223(97)00352-1  1
1998 Hutton M, Lendon CL, Rizzu P, Baker M, Froelich S, Houlden H, Pickering-Brown S, Chakraverty S, Isaacs A, Grover A, Hackett J, Adamson J, Lincoln S, Dickson D, Davies P, ... ... Lannfelt L, et al. Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17. Nature. 393: 702-5. PMID 9641683 DOI: 10.1038/31508  1
1998 Kowalska A, Wender M, Lannfelt L. Lack of association between an intronic polymorphism in the presenilin-1 gene and sporadic late-onset Alzheimer disease in Polish patients. Dementia and Geriatric Cognitive Disorders. 9: 137-9. PMID 9622000 DOI: 10.1159/000017037  1
1998 Kostulas K, Crisby M, Huang WX, Lannfelt L, Hagenfeldt L, Eggertsen G, Kostulas V, Hillert J. A methylenetetrahydrofolate reductase gene polymorphism in ischaemic stroke and in carotid artery stenosis. European Journal of Clinical Investigation. 28: 285-9. PMID 9615905  1
1998 Axelman K, Basun H, Lannfelt L. Wide range of disease onset in a family with Alzheimer disease and a His163Tyr mutation in the presenilin-1 gene. Archives of Neurology. 55: 698-702. PMID 9605727  1
1998 Jelic V, Blomberg M, Dierks T, Basun H, Shigeta M, Julin P, Jensen M, Lannfelt L, Winblad B, Wahlund LO. EEG slowing and cerebrospinal fluid tau levels in patients with cognitive decline. Neuroreport. 9: 157-60. PMID 9592068 DOI: 10.1097/00001756-199801050-00032  1
1998 Lannfelt L. Biochemical diagnostic markers to detect early Alzheimer's disease. Neurobiology of Aging. 19: 165-7. PMID 9558156 DOI: 10.1016/S0197-4580(98)00012-8  0.01
1998 Davies P, Resnick J, Resnick B, Gilman S, Growdon JH, Khachaturian ZS, Radebaugh TS, Roses AD, Selkoe DJ, Trojanowski JQ, Blass JP, Gibson GE, Sheu KFR, Blennow K, Delacourte A, ... ... Lannfelt L, et al. Consensus report of the working group on: 'Molecular and biochemical markers of Alzheimer's disease' Neurobiology of Aging. 19: 109-116. PMID 9558143 DOI: 10.1016/S0197-4580(98)00022-0  1
1998 Julin P, Almkvist O, Basun H, Lannfelt L, Svensson L, Winblad B, Wahlund LO. Brain volumes and regional cerebral blood flow in carriers of the Swedish Alzheimer amyloid protein mutation. Alzheimer Disease and Associated Disorders. 12: 49-53. PMID 9539411 DOI: 10.1097/00002093-199803000-00008  1
1997 Johnston JA, Lannfelt L, Wiehager B, O'Neill C, Cowburn RF. Amyloid precursor protein heat shock response in lymphoblastoid cell lines bearing presenilin-1 mutations. Biochimica Et Biophysica Acta. 1362: 183-92. PMID 9540849 DOI: 10.1016/S0925-4439(97)00074-4  1
1997 Bergem AL, Lannfelt L. Apolipoprotein E type epsilon4 allele, heritability and age at onset in twins with Alzheimer disease and vascular dementia. Clinical Genetics. 52: 408-13. PMID 9520135  0.01
1997 Gibson GE, Vestling M, Zhang H, Szolosi S, Alkon D, Lannfelt L, Gandy S, Cowburn RF. Abnormalities in Alzheimer's disease fibroblasts bearing the APP670/671 mutation. Neurobiology of Aging. 18: 573-80. PMID 9461055 DOI: 10.1016/S0197-4580(97)00149-8  1
1997 Large V, Hellström L, Reynisdottir S, Lönnqvist F, Eriksson P, Lannfelt L, Arner P. Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function. The Journal of Clinical Investigation. 100: 3005-13. PMID 9399946 DOI: 10.1172/Jci119854  0.01
1997 Lannfelt L. The genetics and pathophysiology of Alzheimer's disease. Journal of Internal Medicine. 242: 281-4. PMID 9366805  0.01
1997 Forsell Y, Corder EH, Basun H, Lannfelt L, Viitanen M, Winblad B. Depression and dementia in relation to apolipoprotein E polymorphism in a population sample age 75+. Biological Psychiatry. 42: 898-903. PMID 9359975 DOI: 10.1016/S0006-3223(96)00468-4  1
1997 Forsell C, Froelich S, Axelman K, Vestling M, Cowburn RF, Lilius L, Johnston JA, Engvall B, Johansson K, Dahlkild A, Ingelson M, St George-Hyslop PH, Lannfelt L. A novel pathogenic mutation (Leu262Phe) found in the presenilin 1 gene in early-onset Alzheimer's disease. Neuroscience Letters. 234: 3-6. PMID 9347932 DOI: 10.1016/S0304-3940(97)00603-4  1
1997 Svensson AL, Warpman U, Hellström-Lindahl E, Bogdanovic N, Lannfelt L, Nordberg A. Nicotinic receptors, muscarinic receptors and choline acetyltransferase activity in the temporal cortex of Alzheimer patients with differing apolipoprotein E genotypes. Neuroscience Letters. 232: 37-40. PMID 9292886 DOI: 10.1016/S0304-3940(97)00573-9  1
1997 Shanahan C, Gibson GE, Cowburn RF, Johnston JA, Wiehager B, Lannfelt L, O'Neill C. G protein subunit levels in fibroblasts from familial Alzheimer's disease patients: lower levels of high molecular weight Gs alpha isoform in patients with decreased beta-adrenergic receptor stimulated cAMP formation. Neuroscience Letters. 232: 33-6. PMID 9292885 DOI: 10.1016/S0304-3940(97)00572-7  1
1997 Froelich S, Basun H, Forsell C, Lilius L, Axelman K, Andreadis A, Lannfelt L. Mapping of a disease locus for familial rapidly progressive frontotemporal dementia to chromosome 17q12-21. American Journal of Medical Genetics. 74: 380-5. PMID 9259373 DOI: 10.1002/(Sici)1096-8628(19970725)74:4<380::Aid-Ajmg8>3.0.Co;2-T  1
1997 Lindh M, Blomberg M, Jensen M, Basun H, Lannfelt L, Engvall B, Scharnagel H, März W, Wahlund LO, Cowburn RF. Cerebrospinal fluid apolipoprotein E (apoE) levels in Alzheimer's disease patients are increased at follow up and show a correlation with levels of tau protein. Neuroscience Letters. 229: 85-8. PMID 9223597 DOI: 10.1016/S0304-3940(97)00429-1  1
1997 Vestling M, Adem A, Racchi M, Gibson GE, Lannfelt L, Cowburn RF. Differential regulation of adenylyl cyclase in fibroblasts from sporadic and familial Alzheimer's disease cases with PS1 and APP mutations. Neuroreport. 8: 2031-5. PMID 9223097  1
1997 Jelic V, Julin P, Shigeta M, Nordberg A, Lannfelt L, Winblad B, Wahlund LO. Apolipoprotein E epsilon4 allele decreases functional connectivity in Alzheimer's disease as measured by EEG coherence. Journal of Neurology, Neurosurgery, and Psychiatry. 63: 59-65. PMID 9221969 DOI: 10.1136/Jnnp.63.1.59  1
1997 Almkvist O, Basun H, Wagner SL, Rowe BA, Wahlund LO, Lannfelt L. Cerebrospinal fluid levels of alpha-secretase-cleaved soluble amyloid precursor protein mirror cognition in a Swedish family with Alzheimer disease and a gene mutation. Archives of Neurology. 54: 641-4. PMID 9152122 DOI: 10.1001/Archneur.1997.00550170111022  1
1997 Basun H, Almkvist O, Axelman K, Brun A, Campbell TA, Collinge J, Forsell C, Froelich S, Wahlund LO, Wetterberg L, Lannfelt L. Clinical characteristics of a chromosome 17-linked rapidly progressive familial frontotemporal dementia. Archives of Neurology. 54: 539-44. PMID 9152110 DOI: 10.1001/Archneur.1997.00550170021010  1
1997 Corder EH, Jelic V, Basun H, Lannfelt L, Valind S, Winblad B, Nordberg A. No difference in cerebral glucose metabolism in patients with Alzheimer disease and differing apolipoprotein E genotypes. Archives of Neurology. 54: 273-7. PMID 9074396 DOI: 10.1001/Archneur.1997.00550150035013  1
1996 Algotsson A, Nordberg A, Lannfelt L, Almkvist O, Winblad B. Apolipoprotein E epsilon4 allele, skin vessel reactivity and vascular risk factors in Alzheimer's disease. Archives of Gerontology and Geriatrics. 22: 223-32. PMID 15374172 DOI: 10.1016/0167-4943(96)00695-4  1
1996 Johnston JA, Norgren S, Ravid R, Wasco W, Winblad B, Lannfelt L, Cowburn RF. Quantification of APP and APLP2 mRNA in APOE genotyped Alzheimer's disease brains. Brain Research. Molecular Brain Research. 43: 85-95. PMID 9037522 DOI: 10.1016/S0169-328X(96)00161-1  1
1996 Johnston JA, Norgren S, Annerén G, Cowburn RF, Lannfelt L. A new quantitative solution hybridisation-RNase protection assay for APP and APLP2 mRNA. Brain Research. Molecular Brain Research. 43: 77-84. PMID 9037521 DOI: 10.1016/S0169-328X(96)00160-X  1
1996 Basun H, Lannfelt L. [Alzheimer disease and related conditions. Increased knowledge. New preparations are on the way]. Lã¤Kartidningen. 93: 4617-9. PMID 8999254  1
1996 Lannfelt L. Genetics of Alzheimer's disease. Acta Neurologica Scandinavica. Supplementum. 168: 25-7. PMID 8997415 DOI: 10.1111/J.1600-0404.1996.Tb00368.X  0.01
1996 Ingelson M, Vanmechelen E, Lannfelt L. Microtubule-associated protein tau in human fibroblasts with the Swedish Alzheimer mutation. Neuroscience Letters. 220: 9-12. PMID 8977136 DOI: 10.1016/S0304-3940(96)13218-3  1
1996 Lannfelt L, Jönsson E, Osby U. [Important current genetic findings in schizophrenia]. Nordisk Medicin. 111: 233-4. PMID 8927538  0.01
1996 Jönsson E, Sedvall G, Brené S, Gustavsson JP, Geijer T, Terenius L, Crocq MA, Lannfelt L, Tylec A, Sokoloff P, Schwartz JC, Wiesel FA. Dopamine-related genes and their relationships to monoamine metabolites in CSF. Biological Psychiatry. 40: 1032-43. PMID 8915563 DOI: 10.1016/0006-3223(95)00581-1  1
1996 Corder EH, Lannfelt L, Basun H. Apolipoprotein E genotype and the rate of decline in probable Alzheimer disease. Archives of Neurology. 53: 1094-5. PMID 8912482  1
1996 Blomberg M, Jensen M, Basun H, Lannfelt L, Wahlund LO. Increasing cerebrospinal fluid tau levels in a subgroup of Alzheimer patients with apolipoprotein E allele epsilon 4 during 14 months follow-up. Neuroscience Letters. 214: 163-6. PMID 8878109 DOI: 10.1016/0304-3940(96)12905-0  1
1996 Kalaria RN, Cohen DL, Greenberg BD, Savage MJ, Bogdanovic NE, Winblad B, Lannfelt L, Adem A. Abundance of the longer A beta 42 in neocortical and cerebrovascular amyloid beta deposits in Swedish familial Alzheimer's disease and Down's syndrome. Neuroreport. 7: 1377-81. PMID 8856679 DOI: 10.1097/00001756-199605310-00009  1
1996 Jönsson E, Lannfelt L, Engvall B, Sedvall G. Lack of association between schizophrenia and the apolipoprotein E epsilon 4 allele. European Archives of Psychiatry and Clinical Neuroscience. 246: 182-4. PMID 8832195 DOI: 10.1007/BF02188951  1
1996 Johnston JA, Froelich S, Lannfelt L, Cowburn RF. Quantification of presenilin-1 mRNA in Alzheimer's disease brains. Febs Letters. 394: 279-84. PMID 8830658 DOI: 10.1016/0014-5793(96)00969-6  1
1996 Sherrington R, Froelich S, Sorbi S, Campion D, Chi H, Rogaeva EA, Levesque G, Rogaev EI, Lin C, Liang Y, Ikeda M, Mar L, Brice A, Agid Y, Percy ME, ... ... Lannfelt L, et al. Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant. Human Molecular Genetics. 5: 985-8. PMID 8817335 DOI: 10.1093/Hmg/5.7.985  1
1996 Liu L, Forsell C, Lilius L, Axelman K, Corder EH, Lannfelt L. Allelic association but only weak evidence for linkage to the apolipoprotein E locus in late-onset Swedish Alzheimer families. American Journal of Medical Genetics. 67: 306-11. PMID 8725748 DOI: 10.1002/(Sici)1096-8628(19960531)67:3<306::Aid-Ajmg7>3.0.Co;2-K  1
1996 Basun H, Corder EH, Guo Z, Lannfelt L, Corder LS, Manton KG, Winblad B, Viitanen M. Apolipoprotein E polymorphism and stroke in a population sample aged 75 years or more. Stroke; a Journal of Cerebral Circulation. 27: 1310-5. PMID 8711793 DOI: 10.1161/01.Str.27.8.1310  1
1996 Scheuner D, Eckman C, Jensen M, Song X, Citron M, Suzuki N, Bird TD, Hardy J, Hutton M, Kukull W, Larson E, Levy-Lahad E, Viitanen M, Peskind E, Poorkaj P, ... ... Lannfelt L, et al. Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nature Medicine. 2: 864-70. PMID 8705854 DOI: 10.1038/Nm0896-864  1
1996 Lannfelt L, Jensen M, Froelich S, Basun H, Näslund J, Nordstadt C. [A model system in cell culture shows pathogenic processes. Biochemical diagnosis in Alzheimer dementia]. Lã¤Kartidningen. 93: 2326-31. PMID 8684035  1
1996 Mann DM, Iwatsubo T, Ihara Y, Cairns NJ, Lantos PL, Bogdanovic N, Lannfelt L, Winblad B, Maat-Schieman ML, Rossor MN. Predominant deposition of amyloid-beta 42(43) in plaques in cases of Alzheimer's disease and hereditary cerebral hemorrhage associated with mutations in the amyloid precursor protein gene. The American Journal of Pathology. 148: 1257-66. PMID 8644866  1
1996 Corder EH, Lannfelt L, Viitanen M, Corder LS, Manton KG, Winblad B, Basun H. Apolipoprotein E genotype determines survival in the oldest old (85 years or older) who have good cognition. Archives of Neurology. 53: 418-22. PMID 8624216 DOI: 10.1001/Archneur.1996.00550050048022  1
1996 Corder EH, Basun H, Lannfelt L, Viitanen M, Winblad B. Attenuation of apolipoprotein E Epsilon4 allele gene dose in late age. Lancet. 347: 542. PMID 8596288 DOI: 10.1016/S0140-6736(96)91173-3  1
1996 Warpman U, Marude A, Hellström-Lindahl E, Lannfelt L, Nordberg A. 721 Neuronal nicotinic receptor impairment and APOE polymorphism in Alzheimer's disease Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80723-8  1
1996 Wahlund LO, Basun H, Ahnkvist O, Julin P, Viitanen M, Axelman K, Nordberg A, Shigeta M, Jelic V, Lannfelt L. 592 Clinical follow up of Swedish families with APP and presenilin I mutations Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80594-X  1
1996 Younkin S, Scheuner D, Song X, Eckman C, Citron M, Suzuki N, Bird T, Hardy J, Hutton M, Lannfelt L, Levy-Lahad E, Peskind E, Poorkaj P, Schellenberg G, Tanzi R, et al. 149 The Presenilin 1 and 2 mutations linked to familial Alzheimer's Disease increase the extracellular concentration of amyloid 0 protein (Aβ) ending at Aβ42(43) Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80151-5  1
1996 Folkesson R, Kosciessa U, Duff K, Hardyt J, Lannfelt L, Winblad B. 81 Preparative isolation of intact 650 kb YAC-APP genomic DNA containing the Swedish amyloid precursor protein 670/671 mutation Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80083-2  1
1996 Younkin SG, Song XH, Scheuner D, Eckman C, Prada C, Jensen J, Lannfelt L, Hardy J, Tanzi R, Schellenberg G, Selkoe D, Suzuki N. The effect of amyloid precursor protein and presenilin mutations on amyloid beta protein Biological Psychiatry. 39: 562. DOI: 10.1016/0006-3223(96)84161-8  1
1995 Perez-Tur J, Froelich S, Prihar G, Crook R, Baker M, Duff K, Wragg M, Busfield F, Lendon C, Clark RF. A mutation in Alzheimer's disease destroying a splice acceptor site in the presenilin-1 gene. Neuroreport. 7: 297-301. PMID 8742474  1
1995 Vestling M, Cowburn RF, Venizelos N, Lannfelt L, Winblad B, Adem A. Characterization of muscarinic acetylcholine receptors in cultured adult skin fibroblasts: effects of the Swedish Alzheimer's disease APP 670/671 mutation on binding levels. Journal of Neural Transmission. Parkinson's Disease and Dementia Section. 10: 1-10. PMID 8619905 DOI: 10.1007/BF02256625  1
1995 Lannfelt L, Basun H, Vigo-Pelfrey C, Wahlund LO, Winblad B, Lieberburg I, Schenk D. Amyloid beta-peptide in cerebrospinal fluid in individuals with the Swedish Alzheimer amyloid precursor protein mutation. Neuroscience Letters. 199: 203-6. PMID 8577398 DOI: 10.1016/0304-3940(95)12059-D  1
1995 Lannfelt L, Pedersen NL, Lilius L, Axelman K, Johansson K, Viitanen M, Gatz M. Apolipoprotein epsilon 4 allele in Swedish twins and siblings with Alzheimer disease. Alzheimer Disease and Associated Disorders. 9: 166-9. PMID 8534415 DOI: 10.1097/00002093-199500930-00008  1
1995 Eriksson S, Janciauskiene S, Lannfelt L. Alpha 1-antichymotrypsin regulates Alzheimer beta-amyloid peptide fibril formation. Proceedings of the National Academy of Sciences of the United States of America. 92: 2313-7. PMID 7892264  0.01
1995 Andersson C, Thunell S, Floderus Y, Forsell C, Lundin G, Anvret M, Lannfelt L, Wetterberg L, Lithner F. Diagnosis of acute intermittent porphyria in northern Sweden: an evaluation of mutation analysis and biochemical methods. Journal of Internal Medicine. 237: 301-8. PMID 7891051  1
1995 Basun H, Lannfelt L. [Alzheimer disease. Great progress in the understanding of causes in spite of lack of adequate treatment and knowledge about markers]. Lã¤Kartidningen. 92: 419-20. PMID 7853918  1
1995 Lannfelt L, Axelman K, Lilius L, Basun H. Genetic counseling in a Swedish Alzheimer family with amyloid precursor protein mutation. American Journal of Human Genetics. 56: 332-5. PMID 7825596  1
1995 Lannfelt L, Lilius L, Viitanen M, Houlden H, Rossor M, Hardy J, Winblad B, Basun H. Microsatellite D21S210 (GT-12) allele frequencies in sporadic Alzheimer's disease. Acta Neurologica Scandinavica. 91: 145-8. PMID 7785426 DOI: 10.1111/J.1600-0404.1995.Tb00422.X  1
1995 Jensen M, Basun H, Lannfelt L. Increased cerebrospinal fluid tau in patients with Alzheimer's disease. Neuroscience Letters. 186: 189-91. PMID 7777193 DOI: 10.1016/0304-3940(95)11297-A  1
1995 Basun H, Grut M, Winblad B, Lannfelt L. Apolipoprotein epsilon 4 allele and disease progression in patients with late-onset Alzheimer's disease. Neuroscience Letters. 183: 32-4. PMID 7746480 DOI: 10.1016/0304-3940(94)11107-T  1
1995 Forsell C, Lannfelt L. Amyloid precursor protein mutation at codon 713 (Ala-->Val) does not cause schizophrenia: non-pathogenic variant found at codon 705 (silent). Neuroscience Letters. 184: 90-3. PMID 7724053 DOI: 10.1016/0304-3940(94)11176-J  1
1995 Jönsson E, Forsell C, Lannfelt L, Sedvall G. Schizophrenia and APP gene mutations. Biological Psychiatry. 37: 135-6. PMID 7718679 DOI: 10.1016/0006-3223(94)00211-K  1
1995 Rogaev EI, Sherrington R, Rogaeva EA, Levesque G, Ikeda M, Liang Y, Chi H, Lin C, Holman K, Tsuda T, Mar L, Sorbi S, Nacmias B, Piacentini S, Amaducci L, ... ... Lannfelt L, et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene Nature. 376: 775-778. PMID 7651536 DOI: 10.1038/376775A0  1
1995 Näslund J, Thyberg J, Tjernberg LO, Wernstedt C, Karlström AR, Bogdanovic N, Gandy SE, Lannfelt L, Terenius L, Nordstedt C. Characterization of stable complexes involving apolipoprotein E and the amyloid beta peptide in Alzheimer's disease brain. Neuron. 15: 219-28. PMID 7619525 DOI: 10.1016/0896-6273(95)90079-9  1
1995 Lannfelt L, Basun H, Wahlund LO, Rowe BA, Wagner SL. Decreased alpha-secretase-cleaved amyloid precursor protein as a diagnostic marker for Alzheimer's disease. Nature Medicine. 1: 829-32. PMID 7585189 DOI: 10.1038/Nm0895-829  1
1995 Corder E, Basun H, Lannfelt L, Viitanen M, Winblad B. Apolipoprotein E-epsilon 4 gene dose. Lancet. 346: 967-8. PMID 7564750 DOI: 10.1016/S0140-6736(95)91588-5  1
1995 Haass C, Lemere CA, Capell A, Citron M, Seubert P, Schenk D, Lannfelt L, Selkoe DJ. The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway. Nature Medicine. 1: 1291-6. PMID 7489411 DOI: 10.1038/Nm1295-1291  1
1994 Lannfelt L, Johnston J, Bogdanovich N, Cowburn R. Amyloid precursor protein gene mutation at codon 670/671 in familial Alzheimer's disease in Sweden. Biochemical Society Transactions. 22: 176-9. PMID 8206219 DOI: 10.1042/Bst0220176  1
1994 Lannfelt L, Basun H, Winblad B. [Alzheimer disease. Strong connection between apolipoprotein E and disease development]. Lã¤Kartidningen. 91: 1500-2. PMID 8183036  1
1994 Norstedt C, Lannfelt L, Winblad B. Alzheimer's disease: a molecular perspective. Journal of Internal Medicine. 235: 195-8. PMID 8120513 DOI: 10.1111/J.1365-2796.1994.Tb01059.X  1
1994 Lilius L, Lannfelt L. No amyloid precursor protein 708 mutation in 50 Swedish Alzheimer's disease patients. Human Genetics. 93: 227-8. PMID 8112758 DOI: 10.1007/Bf00210624  1
1994 Haltia M, Viitanen M, Sulkava R, Ala-Hurula V, Poyhonen M, Goldfarb L, Brown P, Levy E, Houlden H, Crook R, Goate A, Clark R, Korenblat K, Pandit S, Keller HD, ... ... Lannfelt L, et al. Chromosome 14-encoded Alzheimer's disease: Genetic and clinicopathological description Annals of Neurology. 36: 362-367. PMID 8080244 DOI: 10.1002/Ana.410360307  1
1994 Näslund J, Schierhorn A, Hellman U, Lannfelt L, Roses AD, Tjernberg LO, Silberring J, Gandy SE, Winblad B, Greengard P. Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging. Proceedings of the National Academy of Sciences of the United States of America. 91: 8378-82. PMID 8078890 DOI: 10.1073/Pnas.91.18.8378  1
1994 Lannfelt L, Lilius L, Nastase M, Viitanen M, Fratiglioni L, Eggertsen G, Berglund L, Angelin B, Linder J, Winblad B. Lack of association between apolipoprotein E allele epsilon 4 and sporadic Alzheimer's disease. Neuroscience Letters. 169: 175-8. PMID 8047277 DOI: 10.1016/0304-3940(94)90384-0  1
1994 Lannfelt L, Bogdanovic N, Appelgren H, Axelman K, Lilius L, Hansson G, Schenk D, Hardy J, Winblad B. Amyloid precursor protein mutation causes Alzheimer's disease in a Swedish family. Neuroscience Letters. 168: 254-6. PMID 8028788 DOI: 10.1016/0304-3940(94)90463-4  1
1994 Citron M, Vigo-Pelfrey C, Teplow DB, Miller C, Schenk D, Johnston J, Winblad B, Venizelos N, Lannfelt L, Selkoe DJ. Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation. Proceedings of the National Academy of Sciences of the United States of America. 91: 11993-7. PMID 7991571 DOI: 10.1073/Pnas.91.25.11993  1
1994 Axelman K, Basun H, Winblad B, Lannfelt L. A large Swedish family with Alzheimer's disease with a codon 670/671 amyloid precursor protein mutation. A clinical and genealogical investigation. Archives of Neurology. 51: 1193-7. PMID 7986173 DOI: 10.1001/Archneur.1994.00540240037013  1
1994 Johnston JA, Cowburn RF, Norgren S, Wiehager B, Venizelos N, Winblad B, Vigo-Pelfrey C, Schenk D, Lannfelt L, O'Neill C. Increased beta-amyloid release and levels of amyloid precursor protein (APP) in fibroblast cell lines from family members with the Swedish Alzheimer's disease APP670/671 mutation. Febs Letters. 354: 274-8. PMID 7957938 DOI: 10.1016/0014-5793(94)01137-0  1
1994 Johnston J, O'Neill C, Lannfelt L, Winblad B, Cowburn RF. The significance of the Swedish APP670/671 mutation for the development of Alzheimer's disease amyloidosis. Neurochemistry International. 25: 73-80. PMID 7950974 DOI: 10.1016/0197-0186(94)90056-6  1
1993 Jönsson E, Lannfelt L, Sokoloff P, Schwartz JC, Sedvall G. Lack of association between schizophrenia and alleles in the dopamine D3 receptor gene. Acta Psychiatrica Scandinavica. 87: 345-9. PMID 8517175 DOI: 10.1111/J.1600-0447.1993.Tb03384.X  1
1993 Lannfelt L, Viitanen M, Johansson K, Axelman K, Lilius L, Almqvist E, Winblad B. Low frequency of the APP 670/671 mutation in familial Alzheimer's disease in Sweden. Neuroscience Letters. 153: 85-7. PMID 8510829 DOI: 10.1016/0304-3940(93)90083-W  1
1993 Mitchell P, Waters B, Vivero C, Le F, Donald J, Tully M, Campedelli K, Lannfelt L, Sokoloff P, Shine J. Exclusion of close linkage of bipolar disorder to the dopamine D3 receptor gene in nine Australian pedigrees. Journal of Affective Disorders. 27: 213-24. PMID 8509522 DOI: 10.1016/0165-0327(93)90045-L  1
1993 Rietschel M, Nöthen MM, Lannfelt L, Sokoloff P, Schwartz JC, Lanczik M, Fritze J, Cichon S, Fimmers R, Körner J. A serine to glycine substitution at position 9 in the extracellular N-terminal part of the dopamine D3 receptor protein: no role in the genetic predisposition to bipolar affective disorder. Psychiatry Research. 46: 253-9. PMID 8493294 DOI: 10.1016/0165-1781(93)90093-V  1
1993 Wiese C, Lannfelt L, Kristbjarnarson H, Yang L, Zoega T, Sokoloff P, Ivarsson O, Schwartz JC, Moises HW, Helgason T. No evidence of linkage between schizophrenia and D3 dopamine receptor gene locus in Icelandic pedigrees. Psychiatry Research. 46: 69-78. PMID 8464957 DOI: 10.1016/0165-1781(93)90009-6  1
1993 Basun H, Garlind A, Lannfelt L. [International Alzheimer research--from management to molecular biology]. Nordisk Medicin. 108: 18-9. PMID 8424050  1
1993 Johnston J, Lilius L, Axelman K, Cowburn R, Johansson K, Viitanen M, Winblad B, Lannfelt L. Sequencing of exons 16 and 17 of the beta-amyloid precursor protein gene fails to identify new mutations in Swedish Alzheimer's disease patients. Human Molecular Genetics. 2: 1045-6. PMID 8364541 DOI: 10.1093/Hmg/2.7.1045  1
1993 Lannfelt L, Lilius L, Appelgren H, Axelman K, Forsell C, Liu L, Johansson K, Graff C. No linkage to chromosome 14 in Swedish Alzheimer's disease families. Nature Genetics. 4: 218-9. PMID 8358427 DOI: 10.1038/Ng0793-218  1
1993 Lannfelt L, Folkesson R, Mohammed AH, Winblad B, Hellgren D, Duff K, Hardy J. Alzheimer's disease: molecular genetics and transgenic animal models. Behavioural Brain Research. 57: 207-13. PMID 8117426 DOI: 10.1016/0166-4328(93)90137-F  1
1993 Yang L, Li T, Wiese C, Lannfelt L, Sokoloff P, Xu CT, Zeng Z, Schwartz JC, Liu X, Moises HW. No association between schizophrenia and homozygosity at the D3 dopamine receptor gene. American Journal of Medical Genetics. 48: 83-6. PMID 8103292 DOI: 10.1002/Ajmg.1320480205  1
1993 Giros B, Sokoloff P, Martres MP, Lannfelt L, Andrieux M, Besançon R, Pilon C, Bouthenet ML, Souil E, Schwartz JC. The third dopamine receptor (D3): new perspectives in therapeutics. Psychopharmacology Series. 10: 82-93. PMID 8103228 DOI: 10.1007/978-3-642-78010-3_8  1
1993 Coon H, Byerley W, Holik J, Hoff M, Myles-Worsley M, Lannfelt L, Sokoloff P, Schwartz JC, Waldo M, Freedman R. Linkage analysis of schizophrenia with five dopamine receptor genes in nine pedigrees. American Journal of Human Genetics. 52: 327-34. PMID 8094267  1
1993 Sagen E, Laegreid A, Anvret M, Lundin G, Lannfelt L, Lilius L, Floderus Y, Romslo I. Genetic carrier detection in Norwegian families with acute intermittent porphyria. Scandinavian Journal of Clinical and Laboratory Investigation. 53: 687-91. PMID 7903821 DOI: 10.3109/00365519309092572  1
1993 Nöthen MM, Körner J, Lannfelt L, Sokoloff P, Schwartz JC, Lanczik M, Rietschel M, Cichon S, Kramer R, Fimmers R, Möller HJ, Beckmann H, Propping P, Grandy DK, Civelli O, et al. Lack of association between schizophrenia and alleles of the dopamine D1, D2, D3 and D4 receptor loci Psychiatric Genetics. 3: 89-94.  1
1992 Mustajoki P, Kauppinen R, Lannfelt L, Lilius L, Koistinen J. Frequency of low erythrocyte porphobilinogen deaminase activity in Finland. Journal of Internal Medicine. 231: 389-95. PMID 1588264  1
1992 Lannfelt L, Nordstedt C. [Alzheimer's disease: put one's own house in order]. Lã¤Kartidningen. 89: 4483-4. PMID 1469994  1
1992 Martres MP, Sokoloff P, Giros B, Bouthenet ML, Pilon C, Lannfelt L, Schwartz JC. [Dopaminergic receptors, multiple targets for neuroleptics]. Annales Mã©Dico-Psychologiques. 150: 119-23. PMID 1364189  1
1992 Crocq MA, Mant R, Asherson P, Williams J, Hode Y, Mayerova A, Collier D, Lannfelt L, Sokoloff P, Schwartz JC. Association between schizophrenia and homozygosity at the dopamine D3 receptor gene. Journal of Medical Genetics. 29: 858-60. PMID 1362221  1
1992 Sokoloff P, Levesque D, Martres MP, Lannfelt L, Diaz G, Pilon C, Schwartz JC. The dopamine D3 receptor as a key target for antipsychotics. Clinical Neuropharmacology. 15: 456A-457A. PMID 1354048  1
1992 Mullan M, Crawford F, Axelman K, Houlden H, Lilius L, Winblad B, Lannfelt L. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid. Nature Genetics. 1: 345-7. PMID 1302033 DOI: 10.1038/Ng0892-345  1
1991 Lilius L, Lannfelt L, Wetterberg L, Floderus Y, Henrichson A, Thunell S. Porphobilinogen deaminase in acute intermittent porphyria: activity and concentration in erythrocytes and lymphocytes. Clinica Chimica Acta; International Journal of Clinical Chemistry. 197: 77-84. PMID 2044216 DOI: 10.1016/0009-8981(91)90350-L  1
1991 Lee JS, Lundin G, Lannfelt L, Forsell L, Picat C, Grandchamp B, Anvret M. Genetic heterogeneity of the porphobilinogen deaminase gene in Swedish families with acute intermittent porphyria. Human Genetics. 87: 484-8. PMID 1679034  1
1990 Lannfelt L. Immunological determination of porphobilinogen deaminase as a diagnostic measure in acute intermittent porphyria. Journal of Clinical Chemistry and Clinical Biochemistry. Zeitschrift Fã¼R Klinische Chemie Und Klinische Biochemie. 28: 273-8. PMID 2380662  0.01
1989 Lannfelt L, Wetterberg L, Lilius L, Thunell S, Gellerfors P. ELISA for measuring porphobilinogen deaminase in human erythrocytes. Clinica Chimica Acta; International Journal of Clinical Chemistry. 183: 227-37. PMID 2791307 DOI: 10.1016/0009-8981(89)90338-0  1
1989 Lannfelt L, Wetterberg L, Lilius L, Thunell S, Jörnvall H, Pavlu B, Wielburski A, Gellerfors P. Porphobilinogen deaminase in human erythrocytes: purification of two forms with apparent molecular weights of 40 kDa and 42 kDa. Scandinavian Journal of Clinical and Laboratory Investigation. 49: 677-84. PMID 2609111  1
1989 Lannfelt L, Wetterberg L, Gellerfors P, Lilius L, Floderus Y, Thunell S. Mutations in acute intermittent porphyria detected by ELISA measurement of porphobilinogen deaminase. Journal of Clinical Chemistry and Clinical Biochemistry. Zeitschrift Fã¼R Klinische Chemie Und Klinische Biochemie. 27: 857-62. PMID 2607315 DOI: 10.1515/Cclm.1989.27.11.857  1
1988 Lee JS, Anvret M, Lindsten J, Lannfelt L, Gellerfors P, Wetterberg L, Floderus Y, Thunell S. DNA polymorphisms within the porphobilinogen deaminase gene in two Swedish families with acute intermittent porphyria. Human Genetics. 79: 379-81. PMID 2900803  1
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