Simon Lovestone, PhD, MRCPsych - Publications

Affiliations: 
Old Age Psychiatry King's College London, London, UK 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=134
Website:
http://www.iop.kcl.ac.uk/staff/profile/default.aspx?go=10554

260 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Robbins JP, Perfect L, Ribe EM, Maresca M, Dangla-Valls A, Foster EM, Killick R, Nowosiad P, Reid MJ, Polit LD, Nevado AJ, Ebner D, Bohlooly-Y M, Buckley N, Pangalos MN, ... ... Lovestone S, et al. Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived Neurons. Frontiers in Neuroscience. 12: 504. PMID 30090055 DOI: 10.3389/fnins.2018.00504  0.36
2017 Sellers KJ, Elliott C, Jackson J, Ghosh A, Ribe E, Rojo-Sanchís A, Jarosz-Griffiths HH, Watson IA, Xia W, Semenov M, Morin P, Hooper NM, Porter R, Preston J, Al-Shawi R, ... ... Lovestone S, et al. Amyloid beta synaptotoxicity is Wnt-planar cell polarity dependent and blocked by fasudil. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29055813 DOI: 10.1016/j.jalz.2017.09.008  0.36
2016 Hakobyan S, Harding K, Aiyaz M, Hye A, Dobson R, Baird A, Liu B, Harris CL, Lovestone S, Morgan BP. Complement Biomarkers as Predictors of Disease Progression in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27567854 DOI: 10.3233/JAD-160420  0.36
2016 Lewis MR, Pearce JT, Spagou K, Green M, Dona AC, Yuen AH, David M, Berry DJ, Chappell K, Horneffer-van der Sluis V, Shaw R, Lovestone S, Elliott P, Shockcor JP, Lindon JC, et al. Development and Application of UPLC-ToF MS for Precision Large Scale Urinary Metabolic Phenotyping. Analytical Chemistry. PMID 27479709 DOI: 10.1021/acs.analchem.6b01481  0.36
2016 Lupton MK, Strike L, Hansell NK, Wen W, Mather KA, Armstrong NJ, Thalamuthu A, McMahon KL, de Zubicaray GI, Assareh AA, Simmons A, Proitsi P, Powell JF, Montgomery GW, Hibar DP, ... ... Lovestone S, et al. The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume. Neurobiology of Aging. 40: 68-77. PMID 26973105 DOI: 10.1016/j.neurobiolaging.2015.12.023  0.36
2016 Orellana C, Ferreira D, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Lovestone S, Simmons A, Wahlund LO, Westman E. Measuring Global Brain Atrophy with the Brain Volume/Cerebrospinal Fluid Index: Normative Values, Cut-Offs and Clinical Associations. Neuro-Degenerative Diseases. 16: 77-86. PMID 26726737 DOI: 10.1159/000442443  0.36
2015 Ritchie CW, Molinuevo JL, Truyen L, Satlin A, Van der Geyten S, Lovestone S. Development of interventions for the secondary prevention of Alzheimer's dementia: the European Prevention of Alzheimer's Dementia (EPAD) project. The Lancet. Psychiatry. PMID 26683239 DOI: 10.1016/S2215-0366(15)00454-X  0.36
2015 Sattlecker M, Khondoker M, Proitsi P, Williams S, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Dobson RJ. Longitudinal Protein Changes in Blood Plasma Associated with the Rate of Cognitive Decline in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 26599049 DOI: 10.3233/JAD-140669  0.36
2015 Falahati F, Ferreira D, Soininen H, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Lovestone S, Eriksdotter M, Wahlund LO, Simmons A, Westman E. The Effect of Age Correction on Multivariate Classification in Alzheimer's Disease, with a Focus on the Characteristics of Incorrectly and Correctly Classified Subjects. Brain Topography. PMID 26440606 DOI: 10.1007/s10548-015-0455-1  0.36
2015 Stephenson D, Hu MT, Romero K, Breen K, Burn D, Ben-Shlomo Y, Bhattaram A, Isaac M, Venuto C, Kubota K, Little MA, Friend S, Lovestone S, Morris HR, Grosset D, et al. Precompetitive Data Sharing as a Catalyst to Address Unmet Needs in Parkinson's Disease1. Journal of Parkinson's Disease. 5: 581-94. PMID 26406139 DOI: 10.3233/JPD-150570  0.36
2015 Chiam JT, Lunnon K, Voyle N, Proitsi P, Coppola G, Geschwind D, Nelson S, Johnston C, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Hodges A, Lovestone S, et al. No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 47: 741-50. PMID 26401708 DOI: 10.3233/JAD-150289  0.36
2015 Andrieu S, Coley N, Lovestone S, Aisen PS, Vellas B. Prevention of sporadic Alzheimer's disease: lessons learned from clinical trials and future directions. The Lancet. Neurology. 14: 926-44. PMID 26213339 DOI: 10.1016/S1474-4422(15)00153-2  0.36
2015 Kiddle SJ, Steves CJ, Mehta M, Simmons A, Xu X, Newhouse S, Sattlecker M, Ashton NJ, Bazenet C, Killick R, Adnan J, Westman E, Nelson S, Soininen H, Kloszewska I, ... ... Lovestone S, et al. Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes. Translational Psychiatry. 5: e584. PMID 26080319 DOI: 10.1038/tp.2015.78  0.36
2015 Lobo SE, Rucker J, Kerr M, Gallo F, Constable G, Hotopf M, Stewart R, Broadbent M, Baggaley M, Lovestone S, McGuffin P, Amarasinghe M, Newman S, Schumann G, Brittain PJ. A comparison of mental state examination documentation by junior clinicians in electronic health records before and after the introduction of a semi-structured assessment template (OPCRIT+). International Journal of Medical Informatics. 84: 675-82. PMID 26033569 DOI: 10.1016/j.ijmedinf.2015.05.001  0.36
2015 Vaudano E, Vannieuwenhuyse B, Van Der Geyten S, van der Lei J, Visser PJ, Streffer J, Ritchie C, McHale D, Lovestone S, Hofmann-Apitius M, Truyen L, Goldman M. Boosting translational research on Alzheimer's disease in Europe: The Innovative Medicine Initiative AD research platform. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25754460 DOI: 10.1016/j.jalz.2015.02.002  0.36
2015 Ferreira D, Cavallin L, Larsson EM, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, K?oszewska I, Soininen H, Lovestone S, Simmons A, Wahlund LO, Westman E. Practical cut-offs for visual rating scales of medial temporal, frontal and posterior atrophy in Alzheimer's disease and mild cognitive impairment. Journal of Internal Medicine. PMID 25752192 DOI: 10.1111/joim.12358  0.36
2015 Vos SJ, Verhey F, Frölich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Nobili F, Morbelli S, Frisoni GB, Drzezga A, Didic M, van Berckel BN, Simmons A, ... ... Lovestone S, et al. Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage. Brain : a Journal of Neurology. 138: 1327-38. PMID 25693589 DOI: 10.1093/brain/awv029  0.36
2015 Khondoker M, Newhouse S, Westman E, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, K?oszewska I, Soininen H, Lovestone S, Dobson R, Simmons A. Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts. Journal of Alzheimer's Disease : Jad. 45: 851-64. PMID 25649652 DOI: 10.3233/JAD-142214  0.36
2015 Proitsi P, Kim M, Whiley L, Pritchard M, Leung R, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Sham P, Lovestone S, Powell JF, Dobson RJ, Legido-Quigley C. Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer's disease. Translational Psychiatry. 5: e494. PMID 25585166 DOI: 10.1038/tp.2014.127  0.36
2015 Nho K, Kim S, Risacher SL, Shen L, Corneveaux JJ, Swaminathan S, Lin H, Ramanan VK, Liu Y, Foroud TM, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, ... ... Lovestone S, et al. Protective variant for hippocampal atrophy identified by whole exome sequencing. Annals of Neurology. 77: 547-52. PMID 25559091 DOI: 10.1002/ana.24349  0.36
2015 . Convergent genetic and expression data implicate immunity in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 658-71. PMID 25533204 DOI: 10.1016/j.jalz.2014.05.1757  0.36
2015 Hallaq R, Volpicelli F, Cuchillo-Ibanez I, Hooper C, Mizuno K, Uwanogho D, Causevic M, Asuni A, To A, Soriano S, Giese KP, Lovestone S, Killick R. The Notch intracellular domain represses CRE-dependent transcription. Cellular Signalling. 27: 621-9. PMID 25479589 DOI: 10.1016/j.cellsig.2014.11.034  0.36
2015 O'Bryant SE, Gupta V, Henriksen K, Edwards M, Jeromin A, Lista S, Bazenet C, Soares H, Lovestone S, Hampel H, Montine T, Blennow K, Foroud T, Carrillo M, Graff-Radford N, et al. Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 549-60. PMID 25282381 DOI: 10.1016/j.jalz.2014.08.099  0.36
2015 Hall A, Muñoz-Ruiz M, Mattila J, Koikkalainen J, Tsolaki M, Mecocci P, Kloszewska I, Vellas B, Lovestone S, Visser PJ, Lötjonen J, Soininen H. Generalizability of the disease state index prediction model for identifying patients progressing from mild cognitive impairment to Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 44: 79-92. PMID 25201784 DOI: 10.3233/JAD-140942  0.36
2015 Dell'Acqua F, Khan W, Gottlieb N, Giampietro V, Ginestet C, Bouls D, Newhouse S, Dobson R, Banaschewski T, Barker GJ, Bokde ALW, Büchel C, Conrod P, Flor H, Frouin V, ... ... Lovestone S, et al. Tract based spatial statistic reveals no differences in white matter microstructural organization between carriers and non-carriers of the APOE ε4 and ε2 alleles in young healthy adolescents Journal of Alzheimer's Disease. 47: 977-984. DOI: 10.3233/JAD-140519  0.36
2015 Ashton NJ, Kiddle SJ, Graf J, Ward M, Baird AL, Hye A, Westwood S, Wong KV, Dobson RJ, Rabinovici GD, Miller BL, Rosen HJ, Torres A, Zhang Z, Thurfjell L, ... ... Lovestone S, et al. Blood protein predictors of brain amyloid for enrichment in clinical trials? Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1: 48-60. DOI: 10.1016/j.dadm.2014.11.005  0.36
2014 Tan GM, Beacher F, Daly E, Horder J, Prasher V, Hanney ML, Morris R, Lovestone S, Murphy KC, Simmons A, Murphy DG. Hippocampal glutamate-glutamine (Glx) in adults with Down syndrome: a preliminary study using in vivo proton magnetic resonance spectroscopy ((1)H MRS). Journal of Neurodevelopmental Disorders. 6: 42. PMID 25937842 DOI: 10.1186/1866-1955-6-42  0.36
2014 Lovestone S. Blood biomarkers for Alzheimer's disease. Genome Medicine. 6: 65. PMID 25473432 DOI: 10.1186/s13073-014-0065-7  0.36
2014 Callard F, Broadbent M, Denis M, Hotopf M, Soncul M, Wykes T, Lovestone S, Stewart R. Developing a new model for patient recruitment in mental health services: a cohort study using Electronic Health Records. Bmj Open. 4: e005654. PMID 25468503 DOI: 10.1136/bmjopen-2014-005654  0.36
2014 Ramanan VK, Nho K, Shen L, Risacher SL, Kim S, McDonald BC, Farlow MR, Foroud TM, Gao S, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, et al. FASTKD2 is associated with memory and hippocampal structure in older adults. Molecular Psychiatry. PMID 25385369 DOI: 10.1038/mp.2014.142  0.36
2014 Lebedev AV, Westman E, Van Westen GJ, Kramberger MG, Lundervold A, Aarsland D, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Simmons A. Random Forest ensembles for detection and prediction of Alzheimer's disease with a good between-cohort robustness. Neuroimage. Clinical. 6: 115-25. PMID 25379423 DOI: 10.1016/j.nicl.2014.08.023  0.36
2014 Khan W, Westman E, Jones N, Wahlund LO, Mecocci P, Vellas B, Tsolaki M, K?oszewska I, Soininen H, Spenger C, Lovestone S, Muehlboeck JS, Simmons A. Automated Hippocampal Subfield Measures as Predictors of Conversion from Mild Cognitive Impairment to Alzheimer's Disease in Two Independent Cohorts. Brain Topography. PMID 25370484 DOI: 10.1007/s10548-014-0415-1  0.36
2014 Proitsi P, Lupton MK, Velayudhan L, Newhouse S, Fogh I, Tsolaki M, Daniilidou M, Pritchard M, Kloszewska I, Soininen H, Mecocci P, Vellas B, Williams J, ... ... Lovestone S, et al. Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a mendelian randomization analysis. Plos Medicine. 11: e1001713. PMID 25226301 DOI: 10.1371/journal.pmed.1001713  0.36
2014 Proitsi P, Lupton MK, Velayudhan L, Hunter G, Newhouse S, Lin K, Fogh I, Tsolaki M, Daniilidou M, Pritchard M, Craig D, Todd S, Johnston JA, McGuinness B, Kloszewska I, ... ... Lovestone S, et al. Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease. Neurobiology of Aging. 35: 2883.e3-2883.e10. PMID 25150574 DOI: 10.1016/j.neurobiolaging.2014.07.023  0.36
2014 Doyle OM, Westman E, Marquand AF, Mecocci P, Vellas B, Tsolaki M, K?oszewska I, Soininen H, Lovestone S, Williams SC, Simmons A. Predicting progression of Alzheimer's disease using ordinal regression. Plos One. 9: e105542. PMID 25141298 DOI: 10.1371/journal.pone.0105542  0.36
2014 Aguilar C, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H, Lovestone S, Wahlund LO, Simmons A, Westman E. Application of a MRI based index to longitudinal atrophy change in Alzheimer disease, mild cognitive impairment and healthy older individuals in the AddNeuroMed cohort. Frontiers in Aging Neuroscience. 6: 145. PMID 25071554 DOI: 10.3389/fnagi.2014.00145  0.36
2014 Hye A, Riddoch-Contreras J, Baird AL, Ashton NJ, Bazenet C, Leung R, Westman E, Simmons A, Dobson R, Sattlecker M, Lupton M, Lunnon K, Keohane A, Ward M, Pike I, ... ... Lovestone S, et al. Plasma proteins predict conversion to dementia from prodromal disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 799-807.e2. PMID 25012867 DOI: 10.1016/j.jalz.2014.05.1749  0.36
2014 Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, ... ... Lovestone S, et al. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. Plos One. 9: e94661. PMID 24922517 DOI: 10.1371/journal.pone.0094661  0.36
2014 Sattlecker M, Kiddle SJ, Newhouse S, Proitsi P, Nelson S, Williams S, Johnston C, Killick R, Simmons A, Westman E, Hodges A, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, ... ... Lovestone S, et al. Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 724-34. PMID 24768341 DOI: 10.1016/j.jalz.2013.09.016  0.36
2014 Lovestone S, Smith U. Advanced glycation end products, dementia, and diabetes. Proceedings of the National Academy of Sciences of the United States of America. 111: 4743-4. PMID 24707042 DOI: 10.1073/pnas.1402277111  0.36
2014 Condliffe D, Wong A, Troakes C, Proitsi P, Patel Y, Chouliaras L, Fernandes C, Cooper J, Lovestone S, Schalkwyk L, Mill J, Lunnon K. Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain. Neurobiology of Aging. 35: 1850-4. PMID 24679604 DOI: 10.1016/j.neurobiolaging.2014.02.002  0.36
2014 Mulugeta E, Vallortigara J, Francis PT, Hye A, Kalaria RN, Perry EK, Lovestone S, Ballard CG. Dynamin protein in stroke and vascular dementia. Neuroscience Letters. 563: 118-22. PMID 24486840 DOI: 10.1016/j.neulet.2014.01.045  0.36
2014 Snyder HM, Carrillo MC, Grodstein F, Henriksen K, Jeromin A, Lovestone S, Mielke MM, O'Bryant S, Sarasa M, Sjøgren M, Soares H, Teeling J, Trushina E, Ward M, West T, et al. Developing novel blood-based biomarkers for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 109-14. PMID 24365657 DOI: 10.1016/j.jalz.2013.10.007  0.36
2014 Khan W, Giampietro V, Ginestet C, Dell'Acqua F, Bouls D, Newhouse S, Dobson R, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, Garavan H, ... ... Lovestone S, et al. No differences in hippocampal volume between carriers and non-carriers of the ApoE ε4 and ε2 alleles in young healthy adolescents. Journal of Alzheimer's Disease : Jad. 40: 37-43. PMID 24326516 DOI: 10.3233/JAD-131841  0.36
2014 Paajanen T, Hänninen T, Tunnard C, Hallikainen M, Mecocci P, Sobow T, Tsolaki M, Vellas B, Lovestone S, Soininen H. CERAD neuropsychological compound scores are accurate in detecting prodromal alzheimer's disease: a prospective AddNeuroMed study. Journal of Alzheimer's Disease : Jad. 39: 679-90. PMID 24246420 DOI: 10.3233/JAD-122110  0.36
2014 Kiddle SJ, Sattlecker M, Proitsi P, Simmons A, Westman E, Bazenet C, Nelson SK, Williams S, Hodges A, Johnston C, Soininen H, KÅ‚oszewska I, Mecocci P, Tsolaki M, Vellas B, ... ... Lovestone S, et al. Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study. Journal of Alzheimer's Disease : Jad. 38: 515-31. PMID 24121966 DOI: 10.3233/JAD-130380  0.36
2014 Pereira JB, Cavallin L, Spulber G, Aguilar C, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Soininen H, Spenger C, Aarsland D, Lovestone S, Simmons A, Wahlund LO, Westman E, et al. Influence of age, disease onset and ApoE4 on visual medial temporal lobe atrophy cut-offs. Journal of Internal Medicine. 275: 317-30. PMID 24118559 DOI: 10.1111/joim.12148  0.36
2014 Proitsi P, Lee SH, Lunnon K, Keohane A, Powell J, Troakes C, Al-Sarraj S, Furney S, Soininen H, KÅ‚oszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Hodges A, et al. Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood. Neurobiology of Aging. 35: 279-90. PMID 24064185 DOI: 10.1016/j.neurobiolaging.2013.08.002  0.36
2014 Whiley L, Sen A, Heaton J, Proitsi P, García-Gómez D, Leung R, Smith N, Thambisetty M, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Lovestone S, Legido-Quigley C, et al. Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease. Neurobiology of Aging. 35: 271-8. PMID 24041970 DOI: 10.1016/j.neurobiolaging.2013.08.001  0.36
2014 Henriksen K, O'Bryant SE, Hampel H, Trojanowski JQ, Montine TJ, Jeromin A, Blennow K, Lönneborg A, Wyss-Coray T, Soares H, Bazenet C, Sjögren M, Hu W, Lovestone S, Karsdal MA, et al. The future of blood-based biomarkers for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 115-31. PMID 23850333 DOI: 10.1016/j.jalz.2013.01.013  0.36
2014 Killick R, Ribe EM, Al-Shawi R, Malik B, Hooper C, Fernandes C, Dobson R, Nolan PM, Lourdusamy A, Furney S, Lin K, Breen G, Wroe R, To AW, Leroy K, ... ... Lovestone S, et al. Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway. Molecular Psychiatry. 19: 88-98. PMID 23164821 DOI: 10.1038/mp.2012.163  0.36
2014 Soares HD, Lovestone S. Biomarker utility in Alzheimer's disease clinical trials Drug Discovery Today: Therapeutic Strategies. DOI: 10.1016/j.ddstr.2013.09.002  0.36
2013 Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, ... ... Lovestone S, et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nature Genetics. 45: 1452-8. PMID 24162737 DOI: 10.1038/ng.2802  0.36
2013 Noble W, Hanger DP, Miller CC, Lovestone S. The importance of tau phosphorylation for neurodegenerative diseases. Frontiers in Neurology. 4: 83. PMID 23847585 DOI: 10.3389/fneur.2013.00083  0.36
2013 Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, ... ... Lovestone S, et al. Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics. Molecular Psychiatry. 18: 739. PMID 23787478 DOI: 10.1038/mp.2013.81  0.36
2013 Leung R, Proitsi P, Simmons A, Lunnon K, Güntert A, Kronenberg D, Pritchard M, Tsolaki M, Mecocci P, Kloszewska I, Vellas B, Soininen H, Wahlund LO, Lovestone S. Inflammatory proteins in plasma are associated with severity of Alzheimer's disease. Plos One. 8: e64971. PMID 23762274 DOI: 10.1371/journal.pone.0064971  0.36
2013 Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, ... ... Lovestone S, et al. Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment. Molecular Psychiatry. 18: 781-7. PMID 23608917 DOI: 10.1038/mp.2013.24  0.36
2013 Velayudhan L, Pritchard M, Powell JF, Proitsi P, Lovestone S. Smell identification function as a severity and progression marker in Alzheimer's disease. International Psychogeriatrics / Ipa. 25: 1157-66. PMID 23597130 DOI: 10.1017/S1041610213000446  0.36
2013 Aguilar C, Westman E, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H, Lovestone S, Spenger C, Simmons A, Wahlund LO. Different multivariate techniques for automated classification of MRI data in Alzheimer's disease and mild cognitive impairment. Psychiatry Research. 212: 89-98. PMID 23541334 DOI: 10.1016/j.pscychresns.2012.11.005  0.36
2013 Brittain PJ, Lobo SE, Rucker J, Amarasinghe M, Anilkumar AP, Baggaley M, Banerjee P, Bearn J, Broadbent M, Butler M, Campbell CD, Cleare AJ, Dratcu L, Frangou S, Gaughran F, ... ... Lovestone S, et al. Harnessing clinical psychiatric data with an electronic assessment tool (OPCRIT+): the utility of symptom dimensions. Plos One. 8: e58790. PMID 23520532 DOI: 10.1371/journal.pone.0058790  0.36
2013 Mangialasche F, Westman E, Kivipelto M, Muehlboeck JS, Cecchetti R, Baglioni M, Tarducci R, Gobbi G, Floridi P, Soininen H, KÅ‚oszewska I, Tsolaki M, Vellas B, Spenger C, Lovestone S, et al. Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol. Journal of Internal Medicine. 273: 602-21. PMID 23343471 DOI: 10.1111/joim.12037  0.36
2013 Spulber G, Simmons A, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Soininen H, Spenger C, Lovestone S, Wahlund LO, Westman E. An MRI-based index to measure the severity of Alzheimer's disease-like structural pattern in subjects with mild cognitive impairment. Journal of Internal Medicine. 273: 396-409. PMID 23278858 DOI: 10.1111/joim.12028  0.36
2013 Killick R, Hughes TR, Morgan BP, Lovestone S. Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH. Neuroscience Letters. 533: 96-9. PMID 23153828 DOI: 10.1016/j.neulet.2012.11.008  0.36
2013 Velayudhan L, Proitsi P, Westman E, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Soininen H, Spenger C, Hodges A, Powell J, Lovestone S, Simmons A. Entorhinal cortex thickness predicts cognitive decline in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 33: 755-66. PMID 23047370 DOI: 10.3233/JAD-2012-121408  0.36
2013 Lunnon K, Sattlecker M, Furney SJ, Coppola G, Simmons A, Proitsi P, Lupton MK, Lourdusamy A, Johnston C, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, Vellas B, Geschwind D, ... Lovestone S, et al. A blood gene expression marker of early Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 33: 737-53. PMID 23042217 DOI: 10.3233/JAD-2012-121363  0.36
2013 Thambisetty M, Beason-Held LL, An Y, Kraut M, Nalls M, Hernandez DG, Singleton AB, Zonderman AB, Ferrucci L, Lovestone S, Resnick SM. Alzheimer risk variant CLU and brain function during aging. Biological Psychiatry. 73: 399-405. PMID 22795969 DOI: 10.1016/j.biopsych.2012.05.026  0.36
2013 Lovestone S. Trait, state, and mechanism: looking back, looking forward, and understanding why. Journal of Alzheimer's Disease : Jad. 33: S23-33. PMID 22710918 DOI: 10.3233/JAD-2012-129014  0.36
2013 Smith BN, Newhouse S, Shatunov A, Vance C, Topp S, Johnson L, Miller J, Lee Y, Troakes C, Scott KM, Jones A, Gray I, Wright J, Hortobágyi T, Al-Sarraj S, ... ... Lovestone S, et al. The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder. European Journal of Human Genetics : Ejhg. 21: 102-8. PMID 22692064 DOI: 10.1038/ejhg.2012.98  0.36
2013 Killick R, Hughes TR, Morgan BP, Lovestone S. Corrigendum to Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH [Neurosci. Lett. 533 (2013) 96-99] Neuroscience Letters. 545: 144. DOI: 10.1016/j.neulet.2013.05.004  0.36
2013 Anagnostopoulos CN, Giannoukos I, Spenger C, Simmons A, Mecocci P, Soininen H, Kłoszewska I, Vellas B, Lovestone S, Tsolaki M. Classification models for Alzheimer'S Disease detection Communications in Computer and Information Science. 384: 193-202. DOI: 10.1007/978-3-642-41016-1_21  0.36
2012 Hooper C, Sainz-Fuertes R, Lynham S, Hye A, Killick R, Warley A, Bolondi C, Pocock J, Lovestone S. Wnt3a induces exosome secretion from primary cultured rat microglia. Bmc Neuroscience. 13: 144. PMID 23173708 DOI: 10.1186/1471-2202-13-144  0.36
2012 Greco I, Day N, Riddoch-Contreras J, Reed J, Soininen H, KÅ‚oszewska I, Tsolaki M, Vellas B, Spenger C, Mecocci P, Wahlund LO, Simmons A, Barnes J, Lovestone S. Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation. Journal of Translational Medicine. 10: 217. PMID 23113945 DOI: 10.1186/1479-5876-10-217  0.36
2012 Kiddle SJ, Thambisetty M, Simmons A, Riddoch-Contreras J, Hye A, Westman E, Pike I, Ward M, Johnston C, Lupton MK, Lunnon K, Soininen H, Kloszewska I, Tsolaki M, Vellas B, ... ... Lovestone S, et al. Plasma based markers of [11C] PiB-PET brain amyloid burden. Plos One. 7: e44260. PMID 23028511 DOI: 10.1371/journal.pone.0044260  0.36
2012 Bazenet C, Lovestone S. Plasma biomarkers for Alzheimer's disease: much needed but tough to find. Biomarkers in Medicine. 6: 441-54. PMID 22917146 DOI: 10.2217/bmm.12.48  0.36
2012 Rogers I, Kerr F, Martinez P, Hardy J, Lovestone S, Partridge L. Ageing increases vulnerability to aβ42 toxicity in Drosophila. Plos One. 7: e40569. PMID 22808195 DOI: 10.1371/journal.pone.0040569  0.36
2012 Davies MN, Volta M, Pidsley R, Lunnon K, Dixit A, Lovestone S, Coarfa C, Harris RA, Milosavljevic A, Troakes C, Al-Sarraj S, Dobson R, Schalkwyk LC, Mill J. Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood. Genome Biology. 13: R43. PMID 22703893 DOI: 10.1186/gb-2012-13-6-r43  0.36
2012 Lourdusamy A, Newhouse S, Lunnon K, Proitsi P, Powell J, Hodges A, Nelson SK, Stewart A, Williams S, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Lovestone S, et al. Identification of cis-regulatory variation influencing protein abundance levels in human plasma. Human Molecular Genetics. 21: 3719-26. PMID 22595970 DOI: 10.1093/hmg/dds186  0.36
2012 Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... ... Lovestone S, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/hmg/dds161  0.36
2012 Lunnon K, Ibrahim Z, Proitsi P, Lourdusamy A, Newhouse S, Sattlecker M, Furney S, Saleem M, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, Vellas B, Coppola G, Geschwind D, ... ... Lovestone S, et al. Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood. Journal of Alzheimer's Disease : Jad. 30: 685-710. PMID 22466004 DOI: 10.3233/JAD-2012-111592  0.36
2012 Shi H, Belbin O, Medway C, Brown K, Kalsheker N, Carrasquillo M, Proitsi P, Powell J, Lovestone S, Goate A, Younkin S, Passmore P, Morgan K. Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS). Neurobiology of Aging. 33: 1849.e5-18. PMID 22445811 DOI: 10.1016/j.neurobiolaging.2012.02.014  0.36
2012 Proitsi P, Lupton MK, Dudbridge F, Tsolaki M, Hamilton G, Daniilidou M, Pritchard M, Lord K, Martin BM, Johnson J, Craig D, Todd S, McGuinness B, Hollingworth P, Harold D, ... ... Lovestone S, et al. Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation. Neurobiology of Aging. 33: 1843.e9-17. PMID 22300950 DOI: 10.1016/j.neurobiolaging.2011.12.036  0.36
2012 Liu Y, Julkunen V, Paajanen T, Westman E, Wahlund LO, Aitken A, Sobow T, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Spenger C, Lovestone S, Simmons A, Soininen H, et al. Education increases reserve against Alzheimer's disease--evidence from structural MRI analysis. Neuroradiology. 54: 929-38. PMID 22246242 DOI: 10.1007/s00234-012-1005-0  0.36
2012 Mangialasche F, Xu W, Kivipelto M, Costanzi E, Ercolani S, Pigliautile M, Cecchetti R, Baglioni M, Simmons A, Soininen H, Tsolaki M, Kloszewska I, Vellas B, Lovestone S, Mecocci P, et al. Tocopherols and tocotrienols plasma levels are associated with cognitive impairment. Neurobiology of Aging. 33: 2282-90. PMID 22192241 DOI: 10.1016/j.neurobiolaging.2011.11.019  0.36
2012 Gerrish A, Russo G, Richards A, Moskvina V, Ivanov D, Harold D, Sims R, Abraham R, Hollingworth P, Chapman J, Hamshere M, Pahwa JS, Dowzell K, Williams A, Jones N, ... ... Lovestone S, et al. The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 28: 377-87. PMID 22027014 DOI: 10.3233/JAD-2011-110824  0.36
2012 Hollingworth P, Sweet R, Sims R, Harold D, Russo G, Abraham R, Stretton A, Jones N, Gerrish A, Chapman J, Ivanov D, Moskvina V, Lovestone S, Priotsi P, Lupton M, et al. Genome-wide association study of Alzheimer's disease with psychotic symptoms. Molecular Psychiatry. 17: 1316-27. PMID 22005930 DOI: 10.1038/mp.2011.125  0.36
2012 Velayudhan L, Killick R, Hye A, Kinsey A, Güntert A, Lynham S, Ward M, Leung R, Lourdusamy A, To AW, Powell J, Lovestone S. Plasma transthyretin as a candidate marker for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 28: 369-75. PMID 22002789 DOI: 10.3233/JAD-2011-110611  0.36
2012 Gilleen J, Greenwood K, Archer N, Lovestone S, David AS. The role of premorbid personality and cognitive factors in awareness of illness, memory, and behavioural functioning in Alzheimer's disease. Cognitive Neuropsychiatry. 17: 227-45. PMID 21929281 DOI: 10.1080/13546805.2011.588007  0.36
2012 Aiyaz M, Lupton MK, Proitsi P, Powell JF, Lovestone S. Complement activation as a biomarker for Alzheimer's disease. Immunobiology. 217: 204-15. PMID 21856034 DOI: 10.1016/j.imbio.2011.07.023  0.36
2012 Thambisetty M, An Y, Kinsey A, Koka D, Saleem M, Güntert A, Kraut M, Ferrucci L, Davatzikos C, Lovestone S, Resnick SM. Plasma clusterin concentration is associated with longitudinal brain atrophy in mild cognitive impairment. Neuroimage. 59: 212-7. PMID 21824521 DOI: 10.1016/j.neuroimage.2011.07.056  0.36
2012 Whitehead D, Tunnard C, Hurt C, Wahlund LO, Mecocci P, Tsolaki M, Vellas B, Spenger C, KÅ‚oszewska I, Soininen H, Cromb D, Lovestone S, Simmons A. Frontotemporal atrophy associated with paranoid delusions in women with Alzheimer's disease. International Psychogeriatrics / Ipa. 24: 99-107. PMID 21740613 DOI: 10.1017/S1041610211000974  0.36
2012 Proitsi P, Lupton MK, Reeves SJ, Hamilton G, Archer N, Martin BM, Iyegbe C, Hollingworth P, Lawlor B, Gill M, Brayne C, Rubinsztein DC, Owen MJ, Williams J, Lovestone S, et al. Association of serotonin and dopamine gene pathways with behavioral subphenotypes in dementia. Neurobiology of Aging. 33: 791-803. PMID 20685009 DOI: 10.1016/j.neurobiolaging.2010.06.011  0.36
2011 Thambisetty M, Simmons A, Hye A, Campbell J, Westman E, Zhang Y, Wahlund LO, Kinsey A, Causevic M, Killick R, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, ... ... Lovestone S, et al. Plasma biomarkers of brain atrophy in Alzheimer's disease. Plos One. 6: e28527. PMID 22205954 DOI: 10.1371/journal.pone.0028527  0.36
2011 Hardy J, Guerreiro R, Lovestone S. Clusterin as an Alzheimer biomarker. Archives of Neurology. 68: 1459-60. PMID 22084130 DOI: 10.1001/archneurol.2011.1000  0.36
2011 Furney SJ, Kronenberg D, Simmons A, Güntert A, Dobson RJ, Proitsi P, Wahlund LO, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Spenger C, Lovestone S. Combinatorial markers of mild cognitive impairment conversion to Alzheimer's disease--cytokines and MRI measures together predict disease progression. Journal of Alzheimer's Disease : Jad. 26: 395-405. PMID 21971479 DOI: 10.3233/JAD-2011-0044  0.36
2011 Westman E, Wahlund LO, Foy C, Poppe M, Cooper A, Murphy D, Spenger C, Lovestone S, Simmons A. Magnetic resonance imaging and magnetic resonance spectroscopy for detection of early Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 26: 307-19. PMID 21971470 DOI: 10.3233/JAD-2011-0028  0.36
2011 Kempton MJ, Underwood TS, Brunton S, Stylios F, Schmechtig A, Ettinger U, Smith MS, Lovestone S, Crum WR, Frangou S, Williams SC, Simmons A. A comprehensive testing protocol for MRI neuroanatomical segmentation techniques: Evaluation of a novel lateral ventricle segmentation method. Neuroimage. 58: 1051-9. PMID 21835253 DOI: 10.1016/j.neuroimage.2011.06.080  0.36
2011 Sims R, Dwyer S, Harold D, Gerrish A, Hollingworth P, Chapman J, Jones N, Abraham R, Ivanov D, Pahwa JS, Moskvina V, Dowzell K, Thomas C, Stretton A, Lovestone S, et al. No evidence that extended tracts of homozygosity are associated with Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 764-71. PMID 21812096 DOI: 10.1002/ajmg.b.31216  0.36
2011 Westman E, Cavallin L, Muehlboeck JS, Zhang Y, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Soininen H, Spenger C, Lovestone S, Simmons A, Wahlund LO. Sensitivity and specificity of medial temporal lobe visual ratings and multivariate regional MRI classification in Alzheimer's disease. Plos One. 6: e22506. PMID 21811624 DOI: 10.1371/journal.pone.0022506  0.36
2011 Rucker J, Newman S, Gray J, Gunasinghe C, Broadbent M, Brittain P, Baggaley M, Denis M, Turp J, Stewart R, Lovestone S, Schumann G, Farmer A, McGuffin P. OPCRIT+: an electronic system for psychiatric diagnosis and data collection in clinical and research settings. The British Journal of Psychiatry : the Journal of Mental Science. 199: 151-5. PMID 21804150 DOI: 10.1192/bjp.bp.110.082925  0.36
2011 Westman E, Simmons A, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Soininen H, Weiner MW, Lovestone S, Spenger C, Wahlund LO. AddNeuroMed and ADNI: similar patterns of Alzheimer's atrophy and automated MRI classification accuracy in Europe and North America. Neuroimage. 58: 818-28. PMID 21763442 DOI: 10.1016/j.neuroimage.2011.06.065  0.36
2011 Hooper C, Killick R, Fernandes C, Cocks G, Sugden D, Lovestone S. Transcriptomic profiles of Wnt3a and insulin in primary cultured rat cortical neurones. Journal of Neurochemistry. 118: 512-20. PMID 21668888 DOI: 10.1111/j.1471-4159.2011.07349.x  0.36
2011 Hopkins PC, Sáinz-Fuertes R, Lovestone S. The impact of a novel apolipoprotein E and amyloid-β protein precursor-interacting protein on the production of amyloid-β. Journal of Alzheimer's Disease : Jad. 26: 239-53. PMID 21593558 DOI: 10.3233/JAD-2011-102115  0.36
2011 Lamar M, Foy CM, Beacher F, Daly E, Poppe M, Archer N, Prasher V, Murphy KC, Morris RG, Simmons A, Lovestone S, Murphy DG. Down syndrome with and without dementia: an in vivo proton Magnetic Resonance Spectroscopy study with implications for Alzheimer's disease. Neuroimage. 57: 63-8. PMID 21504795 DOI: 10.1016/j.neuroimage.2011.03.073  0.36
2011 Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, ... ... Lovestone S, et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nature Genetics. 43: 429-35. PMID 21460840 DOI: 10.1038/ng.803  0.36
2011 Lupton MK, Proitsi P, Danillidou M, Tsolaki M, Hamilton G, Wroe R, Pritchard M, Lord K, Martin BM, Kloszewska I, Soininen H, Mecocci P, Vellas B, Harold D, Hollingworth P, ... Lovestone S, et al. Deep sequencing of the Nicastrin gene in pooled DNA, the identification of genetic variants that affect risk of Alzheimer's disease. Plos One. 6: e17298. PMID 21364883 DOI: 10.1371/journal.pone.0017298  0.36
2011 To AW, Ribe EM, Chuang TT, Schroeder JE, Lovestone S. The ε3 and ε4 alleles of human APOE differentially affect tau phosphorylation in hyperinsulinemic and pioglitazone treated mice. Plos One. 6: e16991. PMID 21347323 DOI: 10.1371/journal.pone.0016991  0.36
2011 Foy CM, Daly EM, Glover A, O'Gorman R, Simmons A, Murphy DG, Lovestone S. Hippocampal proton MR spectroscopy in early Alzheimer's disease and mild cognitive impairment. Brain Topography. 24: 316-22. PMID 21298332 DOI: 10.1007/s10548-011-0170-5  0.36
2011 Costafreda SG, Dinov ID, Tu Z, Shi Y, Liu CY, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Wahlund LO, Spenger C, Toga AW, Lovestone S, Simmons A. Automated hippocampal shape analysis predicts the onset of dementia in mild cognitive impairment. Neuroimage. 56: 212-9. PMID 21272654 DOI: 10.1016/j.neuroimage.2011.01.050  0.36
2011 Simmons A, Westman E, Muehlboeck S, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Wahlund LO, Soininen H, Lovestone S, Evans A, Spenger C. The AddNeuroMed framework for multi-centre MRI assessment of Alzheimer's disease: experience from the first 24 months. International Journal of Geriatric Psychiatry. 26: 75-82. PMID 21157852 DOI: 10.1002/gps.2491  0.36
2011 Hampel H, Wilcock G, Andrieu S, Aisen P, Blennow K, Broich K, Carrillo M, Fox NC, Frisoni GB, Isaac M, Lovestone S, Nordberg A, Prvulovic D, Sampaio C, Scheltens P, et al. Biomarkers for Alzheimer's disease therapeutic trials. Progress in Neurobiology. 95: 579-93. PMID 21130138 DOI: 10.1016/j.pneurobio.2010.11.005  0.36
2011 Furney SJ, Simmons A, Breen G, Pedroso I, Lunnon K, Proitsi P, Hodges A, Powell J, Wahlund LO, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Spenger C, ... ... Lovestone S, et al. Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Molecular Psychiatry. 16: 1130-8. PMID 21116278 DOI: 10.1038/mp.2010.123  0.36
2011 Tunnard C, Whitehead D, Hurt C, Wahlund LO, Mecocci P, Tsolaki M, Vellas B, Spenger C, KÅ‚oszewska I, Soininen H, Lovestone S, Simmons A. Apathy and cortical atrophy in Alzheimer's disease. International Journal of Geriatric Psychiatry. 26: 741-8. PMID 20872914 DOI: 10.1002/gps.2603  0.36
2011 Westman E, Simmons A, Zhang Y, Muehlboeck JS, Tunnard C, Liu Y, Collins L, Evans A, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Soininen H, Lovestone S, Spenger C, et al. Multivariate analysis of MRI data for Alzheimer's disease, mild cognitive impairment and healthy controls. Neuroimage. 54: 1178-87. PMID 20800095 DOI: 10.1016/j.neuroimage.2010.08.044  0.36
2011 Kerr F, Augustin H, Piper MD, Gandy C, Allen MJ, Lovestone S, Partridge L. Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease. Neurobiology of Aging. 32: 1977-89. PMID 19969390 DOI: 10.1016/j.neurobiolaging.2009.10.015  0.36
2011 Liu Y, Paajanen T, Zhang Y, Westman E, Wahlund LO, Simmons A, Tunnard C, Sobow T, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Evans A, Spenger C, Lovestone S, et al. Combination analysis of neuropsychological tests and structural MRI measures in differentiating AD, MCI and control groups--the AddNeuroMed study. Neurobiology of Aging. 32: 1198-206. PMID 19683363 DOI: 10.1016/j.neurobiolaging.2009.07.008  0.36
2011 Proitsi P, Hamilton G, Tsolaki M, Lupton M, Daniilidou M, Hollingworth P, Archer N, Foy C, Stylios F, McGuinness B, Todd S, Lawlor B, Gill M, Brayne C, Rubinsztein DC, ... ... Lovestone S, et al. A Multiple Indicators Multiple Causes (MIMIC) model of Behavioural and Psychological Symptoms in Dementia (BPSD). Neurobiology of Aging. 32: 434-42. PMID 19386383 DOI: 10.1016/j.neurobiolaging.2009.03.005  0.36
2011 Furney SJ, Kronenberg D, Simmons A, Güntert A, Dobson RJ, Proitsi P, Wahlund LO, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Spenger C, Lovestone S. Combinatorial markers of mild cognitive impairment conversion to Alzheimer's disease-cytokines and MRI measures together predict disease progression Advances in Alzheimer's Disease. 2: 789-799. DOI: 10.3233/978-1-60750-793-2-789  0.36
2011 Hamou A, Simmons A, Bauer M, Lewden B, Zhang Y, Wahlund LO, Westman E, Pritchard M, Kloszewska I, Mecozzi P, Soininen H, Tsolaki M, Vellas B, Muehlboeck S, Evans A, ... ... Lovestone S, et al. Cluster analysis of MR imaging in Alzheimer's disease using decision tree refinement International Journal of Artificial Intelligence. 6: 90-99.  0.36
2010 Lovestone S. Searching for biomarkers in neurodegeneration. Nature Medicine. 16: 1371-2. PMID 21135840 DOI: 10.1038/nm1210-1371b  0.36
2010 Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, Pocklington A, Abraham R, Hollingworth P, Sims R, Gerrish A, Pahwa JS, Jones N, Stretton A, Morgan AR, ... Lovestone S, et al. Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. Plos One. 5: e13950. PMID 21085570 DOI: 10.1371/journal.pone.0013950  0.36
2010 Paajanen T, Hänninen T, Tunnard C, Mecocci P, Sobow T, Tsolaki M, Vellas B, Lovestone S, Soininen H, Addneuromed Consortium. CERAD neuropsychological battery total score in multinational mild cognitive impairment and control populations: the AddNeuroMed study. Journal of Alzheimer's Disease : Jad. 22: 1089-97. PMID 20930314 DOI: 10.3233/JAD-2010-100459  0.36
2010 Thambisetty M, Tripaldi R, Riddoch-Contreras J, Hye A, An Y, Campbell J, Sojkova J, Kinsey A, Lynham S, Zhou Y, Ferrucci L, Wong DF, Lovestone S, Resnick SM. Proteome-based plasma markers of brain amyloid-β deposition in non-demented older individuals. Journal of Alzheimer's Disease : Jad. 22: 1099-109. PMID 20930274 DOI: 10.3233/JAD-2010-101350  0.36
2010 Cruchaga C, Kauwe JS, Mayo K, Spiegel N, Bertelsen S, Nowotny P, Shah AR, Abraham R, Hollingworth P, Harold D, Owen MM, Williams J, Lovestone S, Peskind ER, Li G, et al. SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease. Plos Genetics. 6: e1001101. PMID 20862329 DOI: 10.1371/journal.pgen.1001101  0.36
2010 Liu Y, Paajanen T, Westman E, Zhang Y, Wahlund LO, Simmons A, Tunnard C, Sobow T, Proitsi P, Powell J, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Evans A, ... ... Lovestone S, et al. APOE ε2 allele is associated with larger regional cortical thicknesses and volumes. Dementia and Geriatric Cognitive Disorders. 30: 229-37. PMID 20847553 DOI: 10.1159/000320136  0.36
2010 Westman E, Wahlund LO, Foy C, Poppe M, Cooper A, Murphy D, Spenger C, Lovestone S, Simmons A. Combining MRI and MRS to distinguish between Alzheimer's disease and healthy controls. Journal of Alzheimer's Disease : Jad. 22: 171-81. PMID 20847449 DOI: 10.3233/JAD-2010-100168  0.36
2010 CauÅ¡ević M, Farooq U, Lovestone S, Killick R. β-Amyloid precursor protein and tau protein levels are differently regulated in human cerebellum compared to brain regions vulnerable to Alzheimer's type neurodegeneration. Neuroscience Letters. 485: 162-6. PMID 20826196 DOI: 10.1016/j.neulet.2010.08.088  0.36
2010 Sofola O, Kerr F, Rogers I, Killick R, Augustin H, Gandy C, Allen MJ, Hardy J, Lovestone S, Partridge L. Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease. Plos Genetics. 6: e1001087. PMID 20824130 DOI: 10.1371/journal.pgen.1001087  0.36
2010 Callard F, Lovestone S, Pritchard M. Giving dementia a voice. Mental Health Today (Brighton, England). 34-5. PMID 20700944  0.36
2010 Liu Y, Paajanen T, Westman E, Wahlund LO, Simmons A, Tunnard C, Sobow T, Proitsi P, Powell J, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Evans A, Spenger C, ... Lovestone S, et al. Effect of APOE ε4 allele on cortical thicknesses and volumes: the AddNeuroMed study. Journal of Alzheimer's Disease : Jad. 21: 947-66. PMID 20693633 DOI: 10.3233/JAD-2010-100201  0.36
2010 Thambisetty M, Simmons A, Velayudhan L, Hye A, Campbell J, Zhang Y, Wahlund LO, Westman E, Kinsey A, Güntert A, Proitsi P, Powell J, Causevic M, Killick R, Lunnon K, ... ... Lovestone S, et al. Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease. Archives of General Psychiatry. 67: 739-48. PMID 20603455 DOI: 10.1001/archgenpsychiatry.2010.78  0.36
2010 Güntert A, Campbell J, Saleem M, O'Brien DP, Thompson AJ, Byers HL, Ward MA, Lovestone S. Plasma gelsolin is decreased and correlates with rate of decline in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 21: 585-96. PMID 20571216 DOI: 10.3233/JAD-2010-100279  0.36
2010 Liu Y, Paajanen T, Zhang Y, Westman E, Wahlund LO, Simmons A, Tunnard C, Sobow T, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Evans A, Spenger C, Lovestone S, et al. Analysis of regional MRI volumes and thicknesses as predictors of conversion from mild cognitive impairment to Alzheimer's disease. Neurobiology of Aging. 31: 1375-85. PMID 20447732 DOI: 10.1016/j.neurobiolaging.2010.01.022  0.36
2010 Thambisetty M, Lovestone S. Blood-based biomarkers of Alzheimer's disease: challenging but feasible. Biomarkers in Medicine. 4: 65-79. PMID 20387303 DOI: 10.2217/bmm.09.84  0.36
2010 Cocks G, Wilde JI, Graham SJ, Bousgouni V, Virley D, Lovestone S, Richardson J. The thiazolidinedione pioglitazone increases cholesterol biosynthetic gene expression in primary cortical neurons by a PPARgamma-independent mechanism. Journal of Alzheimer's Disease : Jad. 19: 631-46. PMID 20110608 DOI: 10.3233/JAD-2010-1266  0.36
2010 Velayudhan L, Poppe M, Archer N, Proitsi P, Brown RG, Lovestone S. Risk of developing dementia in people with diabetes and mild cognitive impairment. The British Journal of Psychiatry : the Journal of Mental Science. 196: 36-40. PMID 20044657 DOI: 10.1192/bjp.bp.109.067942  0.36
2010 Kauwe JS, Bertelsen S, Mayo K, Cruchaga C, Abraham R, Hollingworth P, Harold D, Owen MJ, Williams J, Lovestone S, Morris JC, Goate AM. Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 955-9. PMID 20029940 DOI: 10.1002/ajmg.b.31053  0.36
2010 Hurt CS, Banerjee S, Tunnard C, Whitehead DL, Tsolaki M, Mecocci P, Kloszewska I, Soininen H, Vellas B, Lovestone S. Insight, cognition and quality of life in Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 81: 331-6. PMID 19828481 DOI: 10.1136/jnnp.2009.184598  0.36
2010 Beacher F, Daly E, Simmons A, Prasher V, Morris R, Robinson C, Lovestone S, Murphy K, Murphy DG. Brain anatomy and ageing in non-demented adults with Down's syndrome: an in vivo MRI study. Psychological Medicine. 40: 611-9. PMID 19671216 DOI: 10.1017/S0033291709990985  0.36
2010 Nicholas H, Moran P, Foy C, Brown RG, Lovestone S, Bryant S, Boothby H. Are abnormal premorbid personality traits associated with Alzheimer's disease? - A case-control study. International Journal of Geriatric Psychiatry. 25: 345-51. PMID 19582776 DOI: 10.1002/gps.2345  0.36
2010 Lupton MK, Stahl D, Archer N, Foy C, Poppe M, Lovestone S, Hollingworth P, Williams J, Owen MJ, Dowzell K, Abraham R, Sims R, Brayne C, Rubinsztein D, Gill M, et al. Education, occupation and retirement age effects on the age of onset of Alzheimer's disease. International Journal of Geriatric Psychiatry. 25: 30-6. PMID 19459177 DOI: 10.1002/gps.2294  0.36
2009 Simmons A, Westman E, Muehlboeck S, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Wahlund LO, Soininen H, Lovestone S, Evans A, Spenger C. MRI measures of Alzheimer's disease and the AddNeuroMed study. Annals of the New York Academy of Sciences. 1180: 47-55. PMID 19906260 DOI: 10.1111/j.1749-6632.2009.05063.x  0.36
2009 Lovestone S, Francis P, Kloszewska I, Mecocci P, Simmons A, Soininen H, Spenger C, Tsolaki M, Vellas B, Wahlund LO, Ward M. AddNeuroMed--the European collaboration for the discovery of novel biomarkers for Alzheimer's disease. Annals of the New York Academy of Sciences. 1180: 36-46. PMID 19906259 DOI: 10.1111/j.1749-6632.2009.05064.x  0.36
2009 Lovestone S. Biomarkers in brain disease. Preface. Annals of the New York Academy of Sciences. 1180: vii. PMID 19906254 DOI: 10.1111/j.1749-6632.2009.05107.x  0.36
2009 Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nature Genetics. 41: 1088-93. PMID 19734902 DOI: 10.1038/ng.440  0.36
2009 Stewart R, Soremekun M, Perera G, Broadbent M, Callard F, Denis M, Hotopf M, Thornicroft G, Lovestone S. The South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLAM BRC) case register: development and descriptive data. Bmc Psychiatry. 9: 51. PMID 19674459 DOI: 10.1186/1471-244X-9-51  0.36
2009 Velayudhan L, Lovestone S. Smell identification test as a treatment response marker in patients with Alzheimer disease receiving donepezil. Journal of Clinical Psychopharmacology. 29: 387-90. PMID 19593181 DOI: 10.1097/JCP.0b013e3181aba5a5  0.36
2009 Killick R, Scales G, Leroy K, Causevic M, Hooper C, Irvine EE, Choudhury AI, Drinkwater L, Kerr F, Al-Qassab H, Stephenson J, Yilmaz Z, Giese KP, Brion JP, Withers DJ, ... Lovestone S, et al. Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice. Biochemical and Biophysical Research Communications. 386: 257-62. PMID 19523444 DOI: 10.1016/j.bbrc.2009.06.032  0.36
2009 Sims R, Hollingworth P, Moskvina V, Dowzell K, O'Donovan MC, Powell J, Lovestone S, Brayne C, Rubinsztein D, Owen MJ, Williams J, Abraham R. Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease. Neuroscience Letters. 461: 54-9. PMID 19477230 DOI: 10.1016/j.neulet.2009.05.051  0.36
2009 Lovestone S, Thambisetty M. Biomarkers for Alzheimer's disease trials--biomarkers for what? A discussion paper. The Journal of Nutrition, Health & Aging. 13: 334-6. PMID 19300870 DOI: 10.1007/s12603-009-0033-x  0.36
2009 Greenberg N, Grassano A, Thambisetty M, Lovestone S, Legido-Quigley C. A proposed metabolic strategy for monitoring disease progression in Alzheimer's disease. Electrophoresis. 30: 1235-9. PMID 19288586 DOI: 10.1002/elps.200800589  0.36
2009 Archer N, Brown RG, Reeves S, Nicholas H, Boothby H, Lovestone S. Midlife Neuroticism and the age of onset of Alzheimer's disease. Psychological Medicine. 39: 665-73. PMID 18694539 DOI: 10.1017/S003329170800408X  0.36
2009 Beacher F, Daly E, Simmons A, Prasher V, Morris R, Robinson C, Lovestone S, Murphy K, Murphy DG. Alzheimer's disease and Down's syndrome: an in vivo MRI study. Psychological Medicine. 39: 675-84. PMID 18667098 DOI: 10.1017/S0033291708004054  0.36
2009 Morgan AR, Hollingworth P, Abraham R, Lovestone S, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J. Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 61-4. PMID 18452187 DOI: 10.1002/ajmg.b.30768  0.36
2009 Lovestone S. Alzheimer's Disease and Other Dementias (Including Pseudodementias) Lishman's Organic Psychiatry: a Textbook of Neuropsychiatry, Fourth Edition. 543-615. DOI: 10.1002/9781444316803.ch9  0.36
2009 Lovestone S. Other Disorders of the Nervous System Lishman's Organic Psychiatry: a Textbook of Neuropsychiatry, Fourth Edition. 845-905. DOI: 10.1002/9781444316803.ch14  0.36
2009 David AS, Fleminger S, Kopelman MD, Lovestone S, Mellers JDC. Lishman's Organic Psychiatry: A Textbook of Neuropsychiatry Lishman's Organic Psychiatry: a Textbook of Neuropsychiatry. 1-933. DOI: 10.1002/9781444316803  0.36
2008 Hooper C, Lovestone S, Sainz-Fuertes R. Alzheimer's Disease, Diagnosis and the Need for Biomarkers. Biomarker Insights. 3: 317-323. PMID 19578515  0.36
2008 Thambisetty M, Hye A, Foy C, Daly E, Glover A, Cooper A, Simmons A, Murphy D, Lovestone S. Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's disease. Journal of Neurology. 255: 1712-20. PMID 19156487 DOI: 10.1007/s00415-008-0006-8  0.36
2008 Winblad B, Frisoni GB, Frolich L, Johannsen P, Johansson G, Kehoe P, Lovestone S, Olde-Rikkert M, Reynish E, Visser PJ, Vellas B. Editorial: EADC (European Alzheimer Disease Consortium) recommendations for future Alzheimer disease research in Europe. The Journal of Nutrition, Health & Aging. 12: 683-4. PMID 19043641  0.36
2008 Kwok JB, Loy CT, Hamilton G, Lau E, Hallupp M, Williams J, Owen MJ, Broe GA, Tang N, Lam L, Powell JF, Lovestone S, Schofield PR. Glycogen synthase kinase-3beta and tau genes interact in Alzheimer's disease. Annals of Neurology. 64: 446-54. PMID 18991351 DOI: 10.1002/ana.21476  0.36
2008 Al-Shawi R, Hafner A, Olsen J, Olson J, Chun S, Raza S, Thrasivoulou C, Lovestone S, Killick R, Simons P, Cowen T. Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system. The European Journal of Neuroscience. 27: 2103-14. PMID 18412630 DOI: 10.1111/j.1460-9568.2008.06152.x  0.36
2008 Macdonald A, Briggs K, Poppe M, Higgins A, Velayudhan L, Lovestone S. A feasibility and tolerability study of lithium in Alzheimer's disease. International Journal of Geriatric Psychiatry. 23: 704-11. PMID 18181229 DOI: 10.1002/gps.1964  0.36
2008 Morgan AR, Hamilton G, Turic D, Jehu L, Harold D, Abraham R, Hollingworth P, Moskvina V, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan M, Powell J, ... Lovestone S, et al. Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 727-31. PMID 18163421 DOI: 10.1002/ajmg.b.30670  0.36
2008 Hooper C, Killick R, Lovestone S. The GSK3 hypothesis of Alzheimer's disease. Journal of Neurochemistry. 104: 1433-9. PMID 18088381 DOI: 10.1111/j.1471-4159.2007.05194.x  0.36
2008 Li Y, Grupe A, Rowland C, Holmans P, Segurado R, Abraham R, Jones L, Catanese J, Ross D, Mayo K, Martinez M, Hollingworth P, Goate A, Cairns NJ, Racette BA, ... ... Lovestone S, et al. Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease. Human Molecular Genetics. 17: 759-67. PMID 18063669 DOI: 10.1093/hmg/ddm348  0.36
2008 Li H, Wetten S, Li L, St Jean PL, Upmanyu R, Surh L, Hosford D, Barnes MR, Briley JD, Borrie M, Coletta N, Delisle R, Dhalla D, Ehm MG, Feldman HH, ... ... Lovestone S, et al. Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Archives of Neurology. 65: 45-53. PMID 17998437 DOI: 10.1001/archneurol.2007.3  0.36
2008 Li Y, Rowland C, Catanese J, Morris J, Lovestone S, O'Donovan MC, Goate A, Owen M, Williams J, Grupe A. SORL1 variants and risk of late-onset Alzheimer's disease. Neurobiology of Disease. 29: 293-6. PMID 17949987 DOI: 10.1016/j.nbd.2007.09.001  0.36
2008 Proitsi P, Li T, Hamilton G, Di Forti M, Collier D, Killick R, Chen R, Sham P, Murray R, Powell J, Lovestone S. Positional pathway screen of wnt signaling genes in schizophrenia: association with DKK4. Biological Psychiatry. 63: 13-6. PMID 17553464 DOI: 10.1016/j.biopsych.2007.03.014  0.36
2008 Al-Shawi R, Hafner A, Olsen J, Chun S, Raza S, Thrasivoulou C, Lovestone S, Killick R, Simons P, Cowen T. Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system (European Journal of Neuroscience (2008) 27, (2103-2114)) European Journal of Neuroscience. 28: 1940. DOI: 10.1111/j.1460-9568.2008.06521.x  0.36
2008 Vellas B, Winblad B, Frisoni G, Frölich L, Johannsen P, Johansson G, Kehoe P, Lovestone S, Olde-Rikkert M, Reynish E, Visser PJ. EADC (European Alzheimer Disease Consortium) recommendations for future Alzheimer disease research in Europe Sinapse. 8: 3-4.  0.36
2007 Ikin AF, Causevic M, Pedrini S, Benson LS, Buxbaum JD, Suzuki T, Lovestone S, Higashiyama S, Mustelin T, Burgoyne RD, Gandy S. Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding. Molecular Neurodegeneration. 2: 23. PMID 18067682 DOI: 10.1186/1750-1326-2-23  0.36
2007 Hamilton G, Proitsi P, Williams J, O'Donovan M, Owen M, Powell J, Lovestone S. Complement factor H Y402H polymorphism is not associated with late-onset Alzheimer's disease. Neuromolecular Medicine. 9: 331-4. PMID 17999207 DOI: 10.1007/s12017-007-8013-y  0.36
2007 Hamshere ML, Holmans PA, Avramopoulos D, Bassett SS, Blacker D, Bertram L, Wiener H, Rochberg N, Tanzi RE, Myers A, Wavrant-De Vrièze F, Go R, Fallin D, Lovestone S, Hardy J, et al. Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease. Human Molecular Genetics. 16: 2703-12. PMID 17725986 DOI: 10.1093/hmg/ddm224  0.36
2007 Lovestone S, Francis P, Strandgaard K. Biomarkers for disease modification trials--the innovative medicines initiative and AddNeuroMed. The Journal of Nutrition, Health & Aging. 11: 359-61. PMID 17653500  0.36
2007 Foy CM, Nicholas H, Hollingworth P, Boothby H, Willams J, Brown RG, Al-Sarraj S, Lovestone S. Diagnosing Alzheimer's disease--non-clinicians and computerised algorithms together are as accurate as the best clinical practice. International Journal of Geriatric Psychiatry. 22: 1154-63. PMID 17530621 DOI: 10.1002/gps.1810  0.36
2007 Hollingworth P, Hamshere ML, Holmans PA, O'Donovan MC, Sims R, Powell J, Lovestone S, Myers A, DeVrieze FW, Hardy J, Goate A, Owen M, Williams J. Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 841-8. PMID 17492769 DOI: 10.1002/ajmg.b.30515  0.36
2007 Hamilton G, Proitsi P, Jehu L, Morgan A, Williams J, O'Donovan MC, Owen MJ, Powell JF, Lovestone S. Candidate gene association study of insulin signaling genes and Alzheimer's disease: evidence for SOS2, PCK1, and PPARgamma as susceptibility loci. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 508-16. PMID 17440948 DOI: 10.1002/ajmg.b.30503  0.36
2007 Harold D, Jehu L, Turic D, Hollingworth P, Moore P, Summerhayes P, Moskvina V, Foy C, Archer N, Hamilton BA, Lovestone S, Powell J, Brayne C, Rubinsztein DC, Jones L, et al. Interaction between the ADAM12 and SH3MD1 genes may confer susceptibility to late-onset Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 448-52. PMID 17440933 DOI: 10.1002/ajmg.b.30456  0.36
2007 Lovestone S, Güntert A, Hye A, Lynham S, Thambisetty M, Ward M. Proteomics of Alzheimer's disease: understanding mechanisms and seeking biomarkers. Expert Review of Proteomics. 4: 227-38. PMID 17425458 DOI: 10.1586/14789450.4.2.227  0.36
2007 Hooper C, Meimaridou E, Tavassoli M, Melino G, Lovestone S, Killick R. p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells. Neuroscience Letters. 418: 34-7. PMID 17399897 DOI: 10.1016/j.neulet.2007.03.026  0.36
2007 Morgan AR, Turic D, Jehu L, Hamilton G, Hollingworth P, Moskvina V, Jones L, Lovestone S, Brayne C, Rubinsztein DC, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J. Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 762-70. PMID 17373700 DOI: 10.1002/ajmg.b.30509  0.36
2007 Lovestone S, Killick R, Di Forti M, Murray R. Schizophrenia as a GSK-3 dysregulation disorder. Trends in Neurosciences. 30: 142-9. PMID 17324475 DOI: 10.1016/j.tins.2007.02.002  0.36
2007 Archer N, Brown RG, Reeves SJ, Boothby H, Nicholas H, Foy C, Williams J, Lovestone S. Premorbid personality and behavioral and psychological symptoms in probable Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 15: 202-13. PMID 17322133 DOI: 10.1097/01.JGP.0000232510.77213.10  0.36
2007 Grupe A, Abraham R, Li Y, Rowland C, Hollingworth P, Morgan A, Jehu L, Segurado R, Stone D, Schadt E, Karnoub M, Nowotny P, Tacey K, Catanese J, Sninsky J, ... ... Lovestone S, et al. Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. Human Molecular Genetics. 16: 865-73. PMID 17317784 DOI: 10.1093/hmg/ddm031  0.36
2007 Hooper C, Chapple JP, Lovestone S, Killick R. The Notch-1 intracellular domain is found in sub-nuclear bodies in SH-SY5Y neuroblastomas and in primary cortical neurons. Neuroscience Letters. 415: 135-9. PMID 17300869 DOI: 10.1016/j.neulet.2007.01.049  0.36
2007 Hooper C, Markevich V, Plattner F, Killick R, Schofield E, Engel T, Hernandez F, Anderton B, Rosenblum K, Bliss T, Cooke SF, Avila J, Lucas JJ, Giese KP, Stephenson J, ... Lovestone S, et al. Glycogen synthase kinase-3 inhibition is integral to long-term potentiation. The European Journal of Neuroscience. 25: 81-6. PMID 17241269 DOI: 10.1111/j.1460-9568.2006.05245.x  0.36
2007 Nayeem N, Kerr F, Naumann H, Linehan J, Lovestone S, Brandner S. Hyperphosphorylation of tau and neurofilaments and activation of CDK5 and ERK1/2 in PTEN-deficient cerebella. Molecular and Cellular Neurosciences. 34: 400-8. PMID 17208451 DOI: 10.1016/j.mcn.2006.11.014  0.36
2007 Ellul J, Archer N, Foy CM, Poppe M, Boothby H, Nicholas H, Brown RG, Lovestone S. The effects of commonly prescribed drugs in patients with Alzheimer's disease on the rate of deterioration. Journal of Neurology, Neurosurgery, and Psychiatry. 78: 233-9. PMID 17012333 DOI: 10.1136/jnnp.2006.104034  0.36
2006 Asuni AA, Hooper C, Reynolds CH, Lovestone S, Anderton BH, Killick R. GSK3alpha exhibits beta-catenin and tau directed kinase activities that are modulated by Wnt. The European Journal of Neuroscience. 24: 3387-92. PMID 17229088 DOI: 10.1111/j.1460-9568.2006.05243.x  0.36
2006 Hooper C, Tavassoli M, Chapple JP, Uwanogho D, Goodyear R, Melino G, Lovestone S, Killick R. TAp73 isoforms antagonize Notch signalling in SH-SY5Y neuroblastomas and in primary neurones. Journal of Neurochemistry. 99: 989-99. PMID 17076661 DOI: 10.1111/j.1471-4159.2006.04142.x  0.36
2006 Hye A, Lynham S, Thambisetty M, Causevic M, Campbell J, Byers HL, Hooper C, Rijsdijk F, Tabrizi SJ, Banner S, Shaw CE, Foy C, Poppe M, Archer N, Hamilton G, ... ... Lovestone S, et al. Proteome-based plasma biomarkers for Alzheimer's disease. Brain : a Journal of Neurology. 129: 3042-50. PMID 17071923 DOI: 10.1093/brain/awl279  0.36
2006 Blacker D, Lovestone S. Genetics and dementia nosology. Journal of Geriatric Psychiatry and Neurology. 19: 186-91. PMID 16880361 DOI: 10.1177/0891988706291091  0.36
2006 Li Y, Grupe A, Rowland C, Nowotny P, Kauwe JS, Smemo S, Hinrichs A, Tacey K, Toombs TA, Kwok S, Catanese J, White TJ, Maxwell TJ, Hollingworth P, Abraham R, ... ... Lovestone S, et al. DAPK1 variants are associated with Alzheimer's disease and allele-specific expression. Human Molecular Genetics. 15: 2560-8. PMID 16847012 DOI: 10.1093/hmg/ddl178  0.36
2006 Hooper C, Killick R, Tavassoli M, Melino G, Lovestone S. TAp73alpha induces tau phosphorylation in HEK293a cells via a transcription-dependent mechanism. Neuroscience Letters. 401: 30-4. PMID 16580132 DOI: 10.1016/j.neulet.2006.02.082  0.36
2006 Hamilton G, Samedi F, Knight J, Archer N, Foy C, Walter S, Turic D, Jehu L, Moore P, Hollingworth P, O'Donovan MC, Williams J, Owen MJ, Lovestone S, Powell JF. Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease. Neuroscience Letters. 401: 77-80. PMID 16574322 DOI: 10.1016/j.neulet.2006.03.021  0.36
2006 Chee F, Mudher A, Newman TA, Cuttle M, Lovestone S, Shepherd D. Overexpression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions. Biochemical Society Transactions. 34: 88-90. PMID 16417489 DOI: 10.1042/BST0340088  0.36
2006 Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, ... ... Lovestone S, et al. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. American Journal of Human Genetics. 78: 78-88. PMID 16385451 DOI: 10.1086/498851  0.36
2006 Smemo S, Nowotny P, Hinrichs AL, Kauwe JS, Cherny S, Erickson K, Myers AJ, Kaleem M, Marlowe L, Gibson AM, Hollingworth P, O'Donovan MC, Morris CM, Holmans P, Lovestone S, et al. Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease. Annals of Neurology. 59: 21-6. PMID 16278862 DOI: 10.1002/ana.20673  0.36
2005 Chee FC, Mudher A, Cuttle MF, Newman TA, MacKay D, Lovestone S, Shepherd D. Over-expression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions. Neurobiology of Disease. 20: 918-28. PMID 16023860 DOI: 10.1016/j.nbd.2005.05.029  0.36
2005 Li Y, Rowland C, Tacey K, Catanese J, Sninsky J, Hardy J, Powell J, Lovestone S, Morris JC, Thal L, Goate A, Owen M, Williams J, Grupe A. The BDNF Val66Met polymorphism is not associated with late onset Alzheimer's disease in three case-control samples. Molecular Psychiatry. 10: 809-10. PMID 15970929 DOI: 10.1038/sj.mp.4001702  0.36
2005 Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell T, Holmans P, Hamshere M, Turic D, Jehu L, Hollingworth P, Moore P, Bryden L, Myers A, Doil LM, Tacey KM, ... ... Lovestone S, et al. Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 136: 62-8. PMID 15858813 DOI: 10.1002/ajmg.b.30186  0.36
2005 Holmes C, Ballard C, Lehmann D, David Smith A, Beaumont H, Day IN, Nadeem Khan M, Lovestone S, McCulley M, Morris CM, Munoz DG, O'Brien K, Russ C, Del Ser T, Warden D. Rate of progression of cognitive decline in Alzheimer's disease: effect of butyrylcholinesterase K gene variation. Journal of Neurology, Neurosurgery, and Psychiatry. 76: 640-3. PMID 15834019 DOI: 10.1136/jnnp.2004.039321  0.36
2005 Holmans P, Hamshere M, Hollingworth P, Rice F, Tunstall N, Jones S, Moore P, Wavrant DeVrieze F, Myers A, Crook R, Compton D, Marshall H, Meyer D, Shears S, Booth J, ... ... Lovestone S, et al. Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 135: 24-32. PMID 15729734 DOI: 10.1002/ajmg.b.30114  0.36
2005 Li Y, Hollingworth P, Moore P, Foy C, Archer N, Powell J, Nowotny P, Holmans P, O'Donovan M, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Lau K, ... ... Lovestone S, et al. Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease. Human Mutation. 25: 270-7. PMID 15714520 DOI: 10.1002/humu.20138  0.36
2005 Deary IJ, Hamilton G, Hayward C, Whalley LJ, Powell J, Starr JM, Lovestone S. Nicastrin gene polymorphisms, cognitive ability level and cognitive ageing. Neuroscience Letters. 373: 110-4. PMID 15567563 DOI: 10.1016/j.neulet.2004.09.073  0.36
2005 Hye A, Kerr F, Archer N, Foy C, Poppe M, Brown R, Hamilton G, Powell J, Anderton B, Lovestone S. Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease. Neuroscience Letters. 373: 1-4. PMID 15555766 DOI: 10.1016/j.neulet.2004.10.031  0.36
2004 Li Y, Nowotny P, Holmans P, Smemo S, Kauwe JS, Hinrichs AL, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Schrodi S, Leong D, Gogic G, Chan J, ... ... Lovestone S, et al. Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family. Proceedings of the National Academy of Sciences of the United States of America. 101: 15688-93. PMID 15507493 DOI: 10.1073/pnas.0403535101  0.36
2004 Li Y, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Schrodi S, Leong D, Lau K, Catanese J, Sninsky J, Nowotny P, Holmans P, Hardy J, Powell J, ... Lovestone S, et al. Association of ABCA1 with late-onset Alzheimer's disease is not observed in a case-control study. Neuroscience Letters. 366: 268-71. PMID 15288432 DOI: 10.1016/j.neulet.2004.05.047  0.36
2004 Busby V, Goossens S, Nowotny P, Hamilton G, Smemo S, Harold D, Turic D, Jehu L, Myers A, Womick M, Woo D, Compton D, Doil LM, Tacey KM, Lau KF, ... ... Lovestone S, et al. Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease. Neuromolecular Medicine. 5: 133-46. PMID 15075440 DOI: 10.1385/NMM:5:2:133  0.36
2004 Cook LJ, Ho LW, Taylor AE, Brayne C, Evans JG, Xuereb J, Cairns NJ, Pritchard A, Lemmon H, Mann D, St Clair D, Turic D, Hollingworth P, Moore PJ, Jehu L, ... ... Lovestone S, et al. Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease. Neuroscience Letters. 358: 142-6. PMID 15026168 DOI: 10.1016/j.neulet.2004.01.016  0.36
2004 Mudher A, Shepherd D, Newman TA, Mildren P, Jukes JP, Squire A, Mears A, Drummond JA, Berg S, MacKay D, Asuni AA, Bhat R, Lovestone S. GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila. Molecular Psychiatry. 9: 522-30. PMID 14993907 DOI: 10.1038/sj.mp.4001483  0.36
2004 Pariante CM, Thomas SA, Lovestone S, Makoff A, Kerwin RW. Do antidepressants regulate how cortisol affects the brain? Psychoneuroendocrinology. 29: 423-47. PMID 14749091 DOI: 10.1016/j.psyneuen.2003.10.009  0.36
2004 Myers AJ, Marshall H, Holmans P, Compton D, Crook RJ, Mander AP, Nowotny P, Smemo S, Dunstan M, Jehu L, Wang JC, Hamshere M, Morris JC, Norton J, Chakraventy S, ... ... Lovestone S, et al. Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 124: 29-37. PMID 14681909 DOI: 10.1002/ajmg.b.20036  0.36
2003 Leroy K, Boutajangout A, Richardson J, Octave JN, Lovestone S, Anderton BH, Brion JP. Mutant presenilin 1 proteins induce cell death and reduce tau-dependent processes outgrowth. Neuroscience Letters. 353: 226-30. PMID 14665422  0.36
2003 Fleminger S, Oliver DL, Lovestone S, Rabe-Hesketh S, Giora A. Head injury as a risk factor for Alzheimer's disease: the evidence 10 years on; a partial replication. Journal of Neurology, Neurosurgery, and Psychiatry. 74: 857-62. PMID 12810767 DOI: 10.1136/jnnp.74.7.857  0.36
2003 Pariante CM, Hye A, Williamson R, Makoff A, Lovestone S, Kerwin RW. The antidepressant clomipramine regulates cortisol intracellular concentrations and glucocorticoid receptor expression in fibroblasts and rat primary neurones. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1553-61. PMID 12784111 DOI: 10.1038/sj.npp.1300195  0.36
2003 Harold D, Peirce T, Moskvina V, Myers A, Jones S, Hollingworth P, Moore P, Lovestone S, Powell J, Foy C, Archer N, Walter S, Edmonson A, McIlroy S, Craig D, et al. Sequence variation in the CHAT locus shows no association with late-onset Alzheimer's disease. Human Genetics. 113: 258-67. PMID 12759818 DOI: 10.1007/s00439-003-0960-2  0.36
2003 Holmes C, Arranz M, Collier D, Powell J, Lovestone S. Depression in Alzheimer's disease: the effect of serotonin receptor gene variation. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 119: 40-3. PMID 12707936 DOI: 10.1002/ajmg.b.10068  0.36
2003 Ljungberg MC, Asuni A, Pearce J, Dayanandan R, März W, Hoffmann MM, Bertrand P, Siest G, Rupniak HT, Anderton BH, Huettinger M, Lovestone S. Apolipoprotein E (apoE) uptake and distribution in mammalian cell lines is dependent upon source of apoE and can be monitored in living cells. Neuroscience Letters. 341: 69-73. PMID 12676346 DOI: 10.1016/S0304-3940(03)00064-8  0.36
2003 Dayanandan R, Butler R, Gordon-Weeks PR, Matus A, Kaech S, Lovestone S, Anderton BH, Gallo JM. Dynamic properties of APC-decorated microtubules in living cells. Cell Motility and the Cytoskeleton. 54: 237-47. PMID 12589682 DOI: 10.1002/cm.10096  0.36
2002 Ljungberg MC, Dayanandan R, Asuni A, Rupniak TH, Anderton BH, Lovestone S. Truncated apoE forms tangle-like structures in a neuronal cell line. Neuroreport. 13: 867-70. PMID 11997703  0.36
2002 Myers A, Wavrant De-Vrieze F, Holmans P, Hamshere M, Crook R, Compton D, Marshall H, Meyer D, Shears S, Booth J, Ramic D, Knowles H, Morris JC, Williams N, Norton N, ... ... Lovestone S, et al. Full genome screen for Alzheimer disease: stage II analysis. American Journal of Medical Genetics. 114: 235-44. PMID 11857588 DOI: 10.1002/ajmg.10183  0.36
2002 Russ C, Lovestone S, Powell JF. Identification of genomic organisation, sequence variants and analysis of the role of the human dishevelled 1 gene in late onset Alzheimer's disease. Molecular Psychiatry. 7: 104-9. PMID 11803455 DOI: 10.1038/sj/mp/4000941  0.36
2002 Lovestone S, McLoughlin DM. Protein aggregates and dementia: is there a common toxicity? Journal of Neurology, Neurosurgery, and Psychiatry. 72: 152-61. PMID 11796764 DOI: 10.1136/jnnp.72.2.152  0.36
2001 Abraham R, Myers A, Wavrant-DeVrieze F, Hamshere ML, Thomas HV, Marshall H, Compton D, Spurlock G, Turic D, Hoogendoorn B, Kwon JM, Petersen RC, Tangalos E, Norton J, Morris JC, ... ... Lovestone S, et al. Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease. Human Genetics. 109: 646-52. PMID 11810277 DOI: 10.1007/s00439-001-0614-1  0.36
2001 Mack TG, Dayanandan R, Van Slegtenhorst M, Whone A, Hutton M, Lovestone S, Anderton BH. Tau proteins with frontotemporal dementia-17 mutations have both altered expression levels and phosphorylation profiles in differentiated neuroblastoma cells. Neuroscience. 108: 701-12. PMID 11738505  0.36
2001 Holmes C, Smith H, Ganderton R, Arranz M, Collier D, Powell J, Lovestone S. Psychosis and aggression in Alzheimer's disease: the effect of dopamine receptor gene variation. Journal of Neurology, Neurosurgery, and Psychiatry. 71: 777-9. PMID 11723200 DOI: 10.1136/jnnp.71.6.777  0.36
2001 Pariante CM, Makoff A, Lovestone S, Feroli S, Heyden A, Miller AH, Kerwin RW. Antidepressants enhance glucocorticoid receptor function in vitro by modulating the membrane steroid transporters. British Journal of Pharmacology. 134: 1335-43. PMID 11704655 DOI: 10.1038/sj.bjp.0704368  0.36
2001 Russ C, Powell JF, Zhao J, Baker M, Hutton M, Crawford F, Mullan M, Roks G, Cruts M, Lovestone S. The microtubule associated protein Tau gene and Alzheimer's disease--an association study and meta-analysis. Neuroscience Letters. 314: 92-6. PMID 11698154 DOI: 10.1016/S0304-3940(01)02289-3  0.36
2001 Killick R, Pollard CC, Asuni AA, Mudher AK, Richardson JC, Rupniak HT, Sheppard PW, Varndell IM, Brion JP, Levey AI, Levy OA, Vestling M, Cowburn R, Lovestone S, Anderton BH. Presenilin 1 independently regulates beta-catenin stability and transcriptional activity. The Journal of Biological Chemistry. 276: 48554-61. PMID 11606587 DOI: 10.1074/jbc.M108332200  0.36
2001 Brion JP, Anderton BH, Authelet M, Dayanandan R, Leroy K, Lovestone S, Octave JN, Pradier L, Touchet N, Tremp G. Neurofibrillary tangles and tau phosphorylation. Biochemical Society Symposium. 81-8. PMID 11447842  0.36
2001 Anderton BH, Betts J, Blackstock WP, Brion JP, Chapman S, Connell J, Dayanandan R, Gallo JM, Gibb G, Hanger DP, Hutton M, Kardalinou E, Leroy K, Lovestone S, Mack T, et al. Sites of phosphorylation in tau and factors affecting their regulation. Biochemical Society Symposium. 73-80. PMID 11447841  0.36
2001 Mudher A, Chapman S, Richardson J, Asuni A, Gibb G, Pollard C, Killick R, Iqbal T, Raymond L, Varndell I, Sheppard P, Makoff A, Gower E, Soden PE, Lewis P, ... ... Lovestone S, et al. Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 4987-95. PMID 11438574  0.36
2001 Liolitsa D, Powell JF, Prince M, Lovestone S. Association study of the 5-HT(2A) receptor gene polymorphism, T102C and essential hypertension. Journal of Human Hypertension. 15: 335-9. PMID 11378836 DOI: 10.1038/sj.jhh.1001177  0.36
2001 Russ C, Lovestone S, Powell JF. Identification of sequence variants and analysis of the role of the glycogen synthase kinase 3 beta gene and promoter in late onset Alzheimer's disease. Molecular Psychiatry. 6: 320-4. PMID 11326302 DOI: 10.1038/sj.mp.4000852  0.36
2001 Connell JW, Gibb GM, Betts JC, Blackstock WP, Gallo J, Lovestone S, Hutton M, Anderton BH. Effects of FTDP-17 mutations on the in vitro phosphorylation of tau by glycogen synthase kinase 3beta identified by mass spectrometry demonstrate certain mutations exert long-range conformational changes. Febs Letters. 493: 40-4. PMID 11278002  0.36
2001 Russ C, Lovestone S, Baker M, Pickering-Brown SM, Andersen PM, Furlong R, Mann D, Powell JF. The extended haplotype of the microtubule associated protein tau gene is not associated with Pick's disease. Neuroscience Letters. 299: 156-8. PMID 11166961 DOI: 10.1016/S0304-3940(00)01785-7  0.36
2000 Reynolds CH, Gibb GM, Lovestone S. Tau phosphorylation both in vitro and in cells. Methods in Molecular Medicine. 32: 375-93. PMID 21318533 DOI: 10.1385/1-59259-195-7:375  0.36
2000 Forlenza OV, Spink JM, Dayanandan R, Anderton BH, Olesen OF, Lovestone S. Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons. Journal of Neural Transmission (Vienna, Austria : 1996). 107: 1201-12. PMID 11129110  0.36
2000 Myers A, Holmans P, Marshall H, Kwon J, Meyer D, Ramic D, Shears S, Booth J, DeVrieze FW, Crook R, Hamshere M, Abraham R, Tunstall N, Rice F, Carty S, ... ... Lovestone S, et al. Susceptibility locus for Alzheimer's disease on chromosome 10. Science (New York, N.Y.). 290: 2304-5. PMID 11125144 DOI: 10.1126/science.290.5500.2304  0.36
2000 Gibb GM, Pearce J, Betts JC, Lovestone S, Hoffmann MM, Maerz W, Blackstock WP, Anderton BH. Differential effects of apolipoprotein E isoforms on phosphorylation at specific sites on tau by glycogen synthase kinase-3 beta identified by nano-electrospray mass spectrometry. Febs Letters. 485: 99-103. PMID 11094148  0.36
2000 Anderton BH, Dayanandan R, Killick R, Lovestone S. Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease? Molecular Medicine Today. 6: 54-9. PMID 10652477  0.36
2000 Leroy K, Menu R, Conreur JL, Dayanandan R, Lovestone S, Anderton BH, Brion JP. The function of the microtubule-associated protein tau is variably modulated by graded changes in glycogen synthase kinase-3beta activity. Febs Letters. 465: 34-8. PMID 10620702  0.36
1999 Lovestone S, Davis DR, Webster MT, Kaech S, Brion JP, Matus A, Anderton BH. Lithium reduces tau phosphorylation: effects in living cells and in neurons at therapeutic concentrations. Biological Psychiatry. 45: 995-1003. PMID 10386182 DOI: 10.1016/S0006-3223(98)00183-8  0.36
1999 Dayanandan R, Van Slegtenhorst M, Mack TG, Ko L, Yen SH, Leroy K, Brion JP, Anderton BH, Hutton M, Lovestone S. Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation. Febs Letters. 446: 228-32. PMID 10100846  0.36
1999 Kehoe P, Wavrant-De Vrieze F, Crook R, Wu WS, Holmans P, Fenton I, Spurlock G, Norton N, Williams H, Williams N, Lovestone S, Perez-Tur J, Hutton M, Chartier-Harlin MC, Shears S, et al. A full genome scan for late onset Alzheimer's disease. Human Molecular Genetics. 8: 237-45. PMID 9931331 DOI: 10.1093/hmg/8.2.237  0.36
1998 Shaw PC, Davies AF, Lau KF, Garcia-Barcelo M, Waye MM, Lovestone S, Miller CC, Anderton BH. Isolation and chromosomal mapping of human glycogen synthase kinase-3 alpha and -3 beta encoding genes. Genome. 41: 720-7. PMID 9809441  0.36
1998 Holmes C, Arranz MJ, Powell JF, Collier DA, Lovestone S. 5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset Alzheimer's disease. Human Molecular Genetics. 7: 1507-9. PMID 9700207 DOI: 10.1093/hmg/7.9.1507  0.36
1998 Gormley N, Rizwan MR, Lovestone S. Clinical predictors of aggressive behaviour in Alzheimer's disease. International Journal of Geriatric Psychiatry. 13: 109-15. PMID 9526180 DOI: 10.1002/(SICI)1099-1166(199802)13:2<109::AID-GPS740>3.0.CO;2-F  0.36
1998 Holmes C, Russ C, Kirov G, Aitchison KJ, Powell JF, Collier DA, Lovestone S. Apolipoprotein E: depressive illness, depressive symptoms, and Alzheimer's disease. Biological Psychiatry. 43: 159-64. PMID 9494696 DOI: 10.1016/S0006-3223(97)00326-0  0.36
1997 Philpot M, Lewis K, Pereria ML, Ward C, Holmes C, Lovestone S, Fensom A, Seller M. Arylsulphatase A pseudodeficiency in vascular dementia and Alzheimer's disease. Neuroreport. 8: 2613-6. PMID 9261837  0.36
1997 Lovestone S, Reynolds CH. The phosphorylation of tau: a critical stage in neurodevelopment and neurodegenerative processes. Neuroscience. 78: 309-24. PMID 9145789  0.36
1996 Holmes C, Levy R, McLoughlin DM, Powell JF, Lovestone S. Apolipoprotein E: non-cognitive symptoms and cognitive decline in late onset Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 61: 580-3. PMID 8971103  0.36
1996 McKeith IG, Galasko D, Kosaka K, Perry EK, Dickson DW, Hansen LA, Salmon DP, Lowe J, Mirra SS, Byrne EJ, Lennox G, Quinn NP, Edwardson JA, Ince PG, Bergeron C, ... ... Lovestone S, et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology. 47: 1113-24. PMID 8909416  0.36
1996 Lovestone S, Hartley CL, Pearce J, Anderton BH. Phosphorylation of tau by glycogen synthase kinase-3 beta in intact mammalian cells: the effects on the organization and stability of microtubules. Neuroscience. 73: 1145-57. PMID 8809831  0.36
1996 Lovestone S, Anderton BH, Hartley C, Jensen TG, Jorgensen AL. The intracellular fate of apolipoprotein E is tau dependent and apoe allele-specific. Neuroreport. 7: 1005-8. PMID 8804040  0.36
1995 Strong C, Anderton BH, Perry RH, Perry EK, Ince PG, Lovestone S. Abnormally phosphorylated tau protein in senile dementia of Lewy body type and Alzheimer disease: evidence that the disorders are distinct. Alzheimer Disease and Associated Disorders. 9: 218-22. PMID 8749611  0.36
1995 Latimer DA, Gallo JM, Lovestone S, Miller CC, Reynolds CH, Marquardt B, Stabel S, Woodgett JR, Anderton BH. Stimulation of MAP kinase by v-raf transformation of fibroblasts fails to induce hyperphosphorylation of transfected tau. Febs Letters. 365: 42-6. PMID 7774712 DOI: 10.1016/0014-5793(95)00434-B  0.36
1995 Anderton BH, Brion JP, Couck AM, Davis DR, Gallo JM, Hanger DP, Ladhani K, Latimer DA, Lewis C, Lovestone S. Modulation of PHF-like tau phosphorylation in cultured neurones and transfected cells. Neurobiology of Aging. 16: 389-97; discussion 3. PMID 7566348 DOI: 10.1016/0197-4580(94)00160-3  0.36
1994 Lovestone S, Reynolds CH, Latimer D, Davis DR, Anderton BH, Gallo JM, Hanger D, Mulot S, Marquardt B, Stabel S. Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. Current Biology : Cb. 4: 1077-86. PMID 7704571 DOI: 10.1016/S0960-9822(00)00246-3  0.36
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