Didier Picard - Publications

Affiliations: 
Cell Biology University of Geneva, Geneva, Switzerland 
Area:
Estrogen Receptor

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Maiti S, Bhattacharya K, Wider D, Hany D, Panasenko O, Bernasconi L, Hulo N, Picard D. Hsf1 and the molecular chaperone Hsp90 support a 'rewiring stress response' leading to an adaptive cell size increase in chronic stress. Elife. 12. PMID 38059913 DOI: 10.7554/eLife.88658  0.738
2023 Hany D, Vafeiadou V, Picard D. CRISPR-Cas9 screen reveals a role of purine synthesis for estrogen receptor α activity and tamoxifen resistance of breast cancer cells. Science Advances. 9: eadd3685. PMID 37172090 DOI: 10.1126/sciadv.add3685  0.717
2023 Hany D, Zoetemelk M, Bhattacharya K, Nowak-Sliwinska P, Picard D. Network-informed discovery of multidrug combinations for ERα+/HER2-/PI3Kα-mutant breast cancer. Cellular and Molecular Life Sciences : Cmls. 80: 80. PMID 36869202 DOI: 10.1007/s00018-023-04730-x  0.78
2022 Bhattacharya K, Maiti S, Zahoran S, Weidenauer L, Hany D, Wider D, Bernasconi L, Quadroni M, Collart M, Picard D. Translational reprogramming in response to accumulating stressors ensures critical threshold levels of Hsp90 for mammalian life. Nature Communications. 13: 6271. PMID 36270993 DOI: 10.1038/s41467-022-33916-3  0.752
2022 Mohammadi Ghahhari N, Sznurkowska MK, Hulo N, Bernasconi L, Aceto N, Picard D. Cooperative interaction between ERα and the EMT-inducer ZEB1 reprograms breast cancer cells for bone metastasis. Nature Communications. 13: 2104. PMID 35440541 DOI: 10.1038/s41467-022-29723-5  0.325
2022 Vafeiadou V, Hany D, Picard D. Hyperactivation of MAPK Induces Tamoxifen Resistance in SPRED2-Deficient ERα-Positive Breast Cancer. Cancers. 14. PMID 35205702 DOI: 10.3390/cancers14040954  0.753
2019 Segala G, Bennesch MA, Ghahhari NM, Pandey DP, Echeverria PC, Karch F, Maeda RK, Picard D. Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling. Nature Communications. 10: 1833. PMID 31015428 DOI: 10.1038/S41467-019-09800-Y  0.321
2019 Echeverria PC, Bhattacharya K, Joshi A, Wang T, Picard D. The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity. Plos One. 14: e0208287. PMID 30726209 DOI: 10.1371/Journal.Pone.0208287  0.391
2018 Berto M, Jean V, Zwart W, Picard D. ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1. Life Science Alliance. 1: e201800055. PMID 30456355 DOI: 10.26508/lsa.201800055  0.4
2018 Neckers L, Blagg B, Haystead T, Trepel JB, Whitesell L, Picard D. Methods to validate Hsp90 inhibitor specificity, to identify off-target effects, and to rethink approaches for further clinical development. Cell Stress & Chaperones. PMID 29392504 DOI: 10.1007/S12192-018-0877-2  0.377
2017 Wider D, Picard D. Secreted dual reporter assay with Gaussia luciferase and the red fluorescent protein mCherry. Plos One. 12: e0189403. PMID 29220385 DOI: 10.1371/Journal.Pone.0189403  0.33
2017 Segala G, David M, de Medina P, Poirot MC, Serhan N, Vergez F, Mougel A, Saland E, Carayon K, Leignadier J, Caron N, Voisin M, Cherier J, Ligat L, Lopez F, ... ... Picard D, et al. Dendrogenin A drives LXR to trigger lethal autophagy in cancers. Nature Communications. 8: 1903. PMID 29199269 DOI: 10.1038/S41467-017-01948-9  0.36
2017 Madon-Simon M, Grad I, Bayo P, Pérez P, Picard D. Defective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23. Plos One. 12: e0180035. PMID 28650975 DOI: 10.1371/Journal.Pone.0180035  0.321
2017 Pupo M, Bodmer A, Berto M, Maggiolini M, Dietrich PY, Picard D. A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between stroma and breast carcinoma cells. Oncotarget. PMID 28596490 DOI: 10.18632/Oncotarget.18156  0.459
2017 Vartholomaiou E, Madon-Simon M, Hagmann S, Mühlebach G, Wurst W, Floss T, Picard D. Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model. Oncotarget. 8: 17428-17442. PMID 28407697 DOI: 10.18632/Oncotarget.15659  0.39
2016 Segala G, Bennesch MA, Pandey DP, Hulo N, Picard D. Monoubiquitination of Histone H2B Blocks Eviction of Histone Variant H2A.Z from Inducible Enhancers. Molecular Cell. PMID 27692985 DOI: 10.1016/J.Molcel.2016.08.034  0.323
2016 Bennesch MA, Segala G, Wider D, Picard D. LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMP. Nucleic Acids Research. PMID 27325688 DOI: 10.1093/Nar/Gkw522  0.528
2016 Wang T, Mäser P, Picard D. Inhibition of Plasmodium falciparum Hsp90 contributes to the antimalarial activities of aminoalcohol-carbazoles. Journal of Medicinal Chemistry. PMID 27312008 DOI: 10.1021/Acs.Jmedchem.6B00591  0.31
2016 De Marco P, Lappano R, Francesco EM, Cirillo F, Pupo M, Avino S, Vivacqua A, Abonante S, Picard D, Maggiolini M. GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response. Scientific Reports. 6: 24354. PMID 27072893 DOI: 10.1038/Srep24354  0.456
2016 Vartholomaiou E, Echeverría PC, Picard D. Unusual Suspects in the Twilight Zone Between the Hsp90 Interactome and Carcinogenesis. Advances in Cancer Research. 129: 1-30. PMID 26915999 DOI: 10.1016/Bs.Acr.2015.08.001  0.378
2015 Bennesch MA, Picard D. Minireview: Tipping the balance: ligand-independent activation of steroid receptors. Molecular Endocrinology (Baltimore, Md.). 29: 349-63. PMID 25625619 DOI: 10.1210/Me.2014-1315  0.41
2014 Rasola A, Neckers L, Picard D. Mitochondrial oxidative phosphorylation TRAP(1)ped in tumor cells. Trends in Cell Biology. 24: 455-63. PMID 24731398 DOI: 10.1016/J.Tcb.2014.03.005  0.317
2014 Wang T, Bisson WH, Mäser P, Scapozza L, Picard D. Differences in conformational dynamics between Plasmodium falciparum and human Hsp90 orthologues enable the structure-based discovery of pathogen-selective inhibitors. Journal of Medicinal Chemistry. 57: 2524-35. PMID 24580531 DOI: 10.1021/Jm401801T  0.306
2013 Fierro-Monti I, Echeverria P, Racle J, Hernandez C, Picard D, Quadroni M. Dynamic impacts of the inhibition of the molecular chaperone Hsp90 on the T-cell proteome have implications for anti-cancer therapy. Plos One. 8: e80425. PMID 24312219 DOI: 10.1371/Journal.Pone.0080425  0.377
2013 Yoshida S, Tsutsumi S, Muhlebach G, Sourbier C, Lee MJ, Lee S, Vartholomaiou E, Tatokoro M, Beebe K, Miyajima N, Mohney RP, Chen Y, Hasumi H, Xu W, Fukushima H, ... ... Picard D, et al. Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis. Proceedings of the National Academy of Sciences of the United States of America. 110: E1604-12. PMID 23564345 DOI: 10.1073/Pnas.1220659110  0.337
2011 Ge X, Rameix-Welti MA, Gault E, Chase G, dos Santos Afonso E, Picard D, Schwemmle M, Naffakh N. Influenza virus infection induces the nuclear relocalization of the Hsp90 co-chaperone p23 and inhibits the glucocorticoid receptor response. Plos One. 6: e23368. PMID 21853119 DOI: 10.1371/Journal.Pone.0023368  0.301
2011 Echeverría PC, Forafonov F, Pandey DP, Mühlebach G, Picard D. Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation. Biodata Mining. 4: 15. PMID 21672238 DOI: 10.1186/1756-0381-4-15  0.303
2011 Lappano R, Recchia AG, De Francesco EM, Angelone T, Cerra MC, Picard D, Maggiolini M. The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor α-mediated signaling in cancer cells and in cardiomyocytes. Plos One. 6: e16631. PMID 21304949 DOI: 10.1371/Journal.Pone.0016631  0.423
2010 Grad I, Cederroth CR, Walicki J, Grey C, Barluenga S, Winssinger N, De Massy B, Nef S, Picard D. The molecular chaperone Hsp90α is required for meiotic progression of spermatocytes beyond pachytene in the mouse. Plos One. 5: e15770. PMID 21209834 DOI: 10.1371/Journal.Pone.0015770  0.344
2010 Carascossa S, Dudek P, Cenni B, Briand PA, Picard D. CARM1 mediates the ligand-independent and tamoxifen-resistant activation of the estrogen receptor alpha by cAMP. Genes & Development. 24: 708-19. PMID 20360387 DOI: 10.1101/Gad.568410  0.487
2010 Echeverria PC, Picard D. Molecular chaperones, essential partners of steroid hormone receptors for activity and mobility. Biochimica Et Biophysica Acta. 1803: 641-9. PMID 20006655 DOI: 10.1016/J.Bbamcr.2009.11.012  0.393
2010 Maggiolini M, Picard D. The unfolding stories of GPR30, a new membrane-bound estrogen receptor. The Journal of Endocrinology. 204: 105-14. PMID 19767412 DOI: 10.1677/Joe-09-0242  0.422
2009 Wider D, Péli-Gulli MP, Briand PA, Tatu U, Picard D. The complementation of yeast with human or Plasmodium falciparum Hsp90 confers differential inhibitor sensitivities. Molecular and Biochemical Parasitology. 164: 147-52. PMID 19320098 DOI: 10.1016/J.Molbiopara.2008.12.011  0.31
2009 Pandey DP, Lappano R, Albanito L, Madeo A, Maggiolini M, Picard D. Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF. The Embo Journal. 28: 523-32. PMID 19153601 DOI: 10.1038/Emboj.2008.304  0.477
2009 Pandey DP, Picard D. miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor α mRNA (Molecular and Cellular Biology (2009) 29, 13, (3783-3790) Molecular and Cellular Biology. 29: 4873. DOI: 10.1128/Mcb.00830-09  0.354
2008 Picard D. A stress protein interface of innate immunity. Embo Reports. 9: 1193-5. PMID 19008919 DOI: 10.1038/Embor.2008.208  0.309
2008 Lev A, Takeda K, Zanker D, Maynard JC, Dimberu P, Waffarn E, Gibbs J, Netzer N, Princiotta MF, Neckers L, Picard D, Nicchitta CV, Chen W, Reiter Y, Bennink JR, et al. The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradation. Immunity. 28: 787-98. PMID 18549799 DOI: 10.1016/J.Immuni.2008.04.015  0.316
2008 Albanito L, Sisci D, Aquila S, Brunelli E, Vivacqua A, Madeo A, Lappano R, Pandey DP, Picard D, Mauro L, Andò S, Maggiolini M. Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells. Endocrinology. 149: 3799-808. PMID 18467441 DOI: 10.1210/En.2008-0117  0.509
2008 Dudek P, Picard D. Genomics of signaling crosstalk of estrogen receptor alpha in breast cancer cells. Plos One. 3: e1859. PMID 18365014 DOI: 10.1371/Journal.Pone.0001859  0.494
2008 Forafonov F, Toogun OA, Grad I, Suslova E, Freeman BC, Picard D. p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity. Molecular and Cellular Biology. 28: 3446-56. PMID 18362168 DOI: 10.1128/Mcb.02246-07  0.366
2007 Grad I, Picard D. The glucocorticoid responses are shaped by molecular chaperones. Molecular and Cellular Endocrinology. 275: 2-12. PMID 17628337 DOI: 10.1016/J.Mce.2007.05.018  0.421
2006 Grad I, McKee TA, Ludwig SM, Hoyle GW, Ruiz P, Wurst W, Floss T, Miller CA, Picard D. The Hsp90 cochaperone p23 is essential for perinatal survival. Molecular and Cellular Biology. 26: 8976-83. PMID 17000766 DOI: 10.1128/Mcb.00734-06  0.311
2006 Vivacqua A, Bonofiglio D, Albanito L, Madeo A, Rago V, Carpino A, Musti AM, Picard D, Andò S, Maggiolini M. 17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30. Molecular Pharmacology. 70: 1414-23. PMID 16835357 DOI: 10.1124/Mol.106.026344  0.415
2006 Picard D. Chaperoning steroid hormone action. Trends in Endocrinology and Metabolism: Tem. 17: 229-35. PMID 16806964 DOI: 10.1016/J.Tem.2006.06.003  0.387
2006 Phelps C, Gburcik V, Suslova E, Dudek P, Forafonov F, Bot N, MacLean M, Fagan RJ, Picard D. Fungi and animals may share a common ancestor to nuclear receptors. Proceedings of the National Academy of Sciences of the United States of America. 103: 7077-81. PMID 16636289 DOI: 10.1073/Pnas.0510080103  0.751
2006 Gburcik V, Picard D. The cell-specific activity of the estrogen receptor alpha may be fine-tuned by phosphorylation-induced structural gymnastics. Nuclear Receptor Signaling. 4: e005. PMID 16604168 DOI: 10.1621/Nrs.04005  0.766
2006 Picard D. Intracellular dynamics of the Hsp90 co-chaperone p23 is dictated by Hsp90. Experimental Cell Research. 312: 198-204. PMID 16289154 DOI: 10.1016/J.Yexcr.2005.10.009  0.322
2006 Vivacqua A, Bonofiglio D, Recchia AG, Musti AM, Picard D, Andò S, Maggiolini M. The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells. Molecular Endocrinology (Baltimore, Md.). 20: 631-46. PMID 16239258 DOI: 10.1210/Me.2005-0280  0.462
2005 MacLean MJ, Llordella MM, Bot N, Picard D. A yeast-based assay reveals a functional defect of the Q488H polymorphism in human Hsp90alpha. Biochemical and Biophysical Research Communications. 337: 133-7. PMID 16171778 DOI: 10.1016/J.Bbrc.2005.09.025  0.323
2005 Leskinen P, Michelini E, Picard D, Karp M, Virta M. Bioluminescent yeast assays for detecting estrogenic and androgenic activity in different matrices. Chemosphere. 61: 259-66. PMID 16168749 DOI: 10.1016/J.Chemosphere.2005.01.080  0.359
2005 Mehenni H, Lin-Marq N, Buchet-Poyau K, Reymond A, Collart MA, Picard D, Antonarakis SE. LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes. Human Molecular Genetics. 14: 2209-19. PMID 15987703 DOI: 10.1093/Hmg/Ddi225  0.321
2005 Gburcik V, Bot N, Maggiolini M, Picard D. SPBP is a phosphoserine-specific repressor of estrogen receptor alpha. Molecular and Cellular Biology. 25: 3421-30. PMID 15831449 DOI: 10.1128/Mcb.25.9.3421-3430.2005  0.779
2004 Maggiolini M, Recchia AG, Carpino A, Vivacqua A, Fasanella G, Rago V, Pezzi V, Briand PA, Picard D, Andò S. Oestrogen receptor beta is required for androgen-stimulated proliferation of LNCaP prostate cancer cells. Journal of Molecular Endocrinology. 32: 777-91. PMID 15171712 DOI: 10.1677/Jme.0.0320777  0.343
2004 Picard D. Hsp90 invades the outside. Nature Cell Biology. 6: 479-80. PMID 15170457 DOI: 10.1038/Ncb0604-479  0.344
2004 Maggiolini M, Vivacqua A, Fasanella G, Recchia AG, Sisci D, Pezzi V, Montanaro D, Musti AM, Picard D, Andò S. The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells. The Journal of Biological Chemistry. 279: 27008-16. PMID 15090535 DOI: 10.1074/Jbc.M403588200  0.476
2004 Donzé O, Deng J, Curran J, Sladek R, Picard D, Sonenberg N. The protein kinase PKR: a molecular clock that sequentially activates survival and death programs. The Embo Journal. 23: 564-71. PMID 14749731 DOI: 10.1038/Sj.Emboj.7600078  0.331
2003 MacLean M, Picard D. Cdc37 goes beyond Hsp90 and kinases. Cell Stress & Chaperones. 8: 114-9. PMID 14627196 DOI: 10.1379/1466-1268(2003)008<0114:Cgbhak>2.0.Co;2  0.37
2003 Riggs DL, Roberts PJ, Chirillo SC, Cheung-Flynn J, Prapapanich V, Ratajczak T, Gaber R, Picard D, Smith DF. The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo. The Embo Journal. 22: 1158-67. PMID 12606580 DOI: 10.1093/Emboj/Cdg108  0.463
2003 Picard D. Molecular mechanisms of cross-talk between growth factors and nuclear receptor signaling Pure and Applied Chemistry. 75: 1743-1756. DOI: 10.1351/Pac200375111743  0.366
2002 Picard D. Heat-shock protein 90, a chaperone for folding and regulation. Cellular and Molecular Life Sciences. 59: 1640-1648. PMID 12475174 DOI: 10.1007/Pl00012491  0.341
2002 Abbas-Terki T, Briand PA, Donzé O, Picard D. The Hsp90 co-chaperones Cdc37 and Sti1 interact physically and genetically. Biological Chemistry. 383: 1335-42. PMID 12437126 DOI: 10.1515/Bc.2002.152  0.347
2002 Maggiolini M, Vivacqua A, Carpino A, Bonofiglio D, Fasanella G, Salerno M, Picard D, Andó S. The mutant androgen receptor T877A mediates the proliferative but not the cytotoxic dose-dependent effects of genistein and quercetin on human LNCaP prostate cancer cells. Molecular Pharmacology. 62: 1027-35. PMID 12391264 DOI: 10.1124/Mol.62.5.1027  0.379
2002 Maggiolini M, Bonofiglio D, Pezzi V, Carpino A, Marsico S, Rago V, Vivacqua A, Picard D, Andò S. Aromatase overexpression enhances the stimulatory effects of adrenal androgens on MCF7 breast cancer cells. Molecular and Cellular Endocrinology. 193: 13-8. PMID 12160997 DOI: 10.1016/S0303-7207(02)00091-6  0.446
2002 Foray N, Marot D, Randrianarison V, Venezia ND, Picard D, Perricaudet M, Favaudon V, Jeggo P. Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation. Molecular and Cellular Biology. 22: 4020-32. PMID 12024016 DOI: 10.1128/Mcb.22.12.4020-4032.2002  0.31
2001 Maggiolini M, Carpino A, Bonofiglio D, Pezzi V, Rago V, Marsico S, Picard D, Andò S. The direct proliferative stimulus of dehydroepiandrosterone on MCF7 breast cancer cells is potentiated by overexpression of aromatase Molecular and Cellular Endocrinology. 184: 163-171. PMID 11694352 DOI: 10.1016/S0303-7207(01)00563-9  0.428
2001 Abbas-Terki T, Donzé O, Briand PA, Picard D. Hsp104 interacts with Hsp90 cochaperones in respiring yeast Molecular and Cellular Biology. 21: 7569-7575. PMID 11604493 DOI: 10.1128/Mcb.21.22.7569-7575.2001  0.32
2001 Maggiolini M, Bonofiglio D, Marsico S, Panno ML, Cenni B, Picard D, Andò S. Estrogen receptor α mediates the proliferative but not the cytotoxic dose-dependent effects of two major phytoestrogens on human breast cancer cells Molecular Pharmacology. 60: 595-602. PMID 11502892  0.36
2001 Donzé O, Abbas-Terki T, Picard D. The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNA-dependent kinase PKR Embo Journal. 20: 3771-3780. PMID 11447118 DOI: 10.1093/Emboj/20.14.3771  0.398
2000 Picard D. Posttranslational regulation of proteins by fusions to steroid-binding domains Methods in Enzymology. 327: 385-401. PMID 11044998 DOI: 10.1016/S0076-6879(00)27291-1  0.421
2000 Scheidegger KJ, Cenni B, Picard D, Delafontaine P. Estradiol decreases IGF-1 and IGF-1 receptor expression in rat aortic smooth muscle cells: Mechanisms for its atheroprotective effects Journal of Biological Chemistry. 275: 38921-38928. PMID 10982795 DOI: 10.1074/Jbc.M004691200  0.338
2000 Abbas-Terki T, Donzé O, Picard D. The molecular chaperone Cdc37 is required for Ste11 function and pheromone-induced cell cycle arrest Febs Letters. 467: 111-116. PMID 10664467 DOI: 10.1016/S0014-5793(00)01134-0  0.393
2000 Donzé O, Picard D. Hsp90 Binds and Regulates Gcn2, the Ligand-Inducible Kinase of the α Subunit of Eukaryotic Translation Initiation Factor 2 Molecular and Cellular Biology. 20: 1897-1897. DOI: 10.1128/Mcb.20.5.1897-1897.2000  0.401
1999 Liu JW, Jeannin E, Picard D. The anti-estrogen hydroxytamoxifen is a potent antagonist in a novel yeast system Biological Chemistry. 380: 1341-1345. PMID 10614829 DOI: 10.1515/Bc.1999.172  0.365
1999 Donzé O, Picard D. Hsp90 binds and regulates the ligand-inducible α subunit of eukaryotic translation initiation factor kinase Gcn2 Molecular and Cellular Biology. 19: 8422-8432. PMID 10567567 DOI: 10.1128/Mcb.19.12.8422  0.401
1999 Abbas-Terki T, Picard D. α-complemented β-galactosidase. An in vivo model substrate for the molecular chaperone-heat-shock protein 90 in yeast European Journal of Biochemistry. 266: 517-523. PMID 10561593 DOI: 10.1046/J.1432-1327.1999.00881.X  0.323
1999 Maggiolini M, Donzé O, Jeannin E, Andö S, Picard D. Adrenal androgens stimulate the proliferation of breast cancer cells as direct activators of estrogen receptor α Cancer Research. 59: 4864-4869. PMID 10519397  0.315
1999 Cenni B, Picard D. Two compounds commonly used for phospholipase C inhibition activate the nuclear estrogen receptors Biochemical and Biophysical Research Communications. 261: 340-344. PMID 10425187 DOI: 10.1006/Bbrc.1999.1017  0.394
1999 Balmelli-Gallacchi P, Schoumacher F, Liu JW, Eppenberger U, Mueller H, Picard D. A yeast-based bioassay for the determination of functional and non-functional estrogen receptors Nucleic Acids Research. 27: 1875-1881. PMID 10101196 DOI: 10.1093/Nar/27.8.1875  0.449
1999 Cenni B, Picard D. Ligand-independent activation of steroid receptors: New roles for old players Trends in Endocrinology and Metabolism. 10: 41-46. DOI: 10.1016/S1043-2760(98)00121-0  0.403
1998 Louvion JF, Abbas-Terki T, Picard D. Hsp90 is required for pheromone signaling in yeast Molecular Biology of the Cell. 9: 3071-3083. PMID 9802897 DOI: 10.1091/Mbc.9.11.3071  0.367
1998 Picard D. Two orphans find a home Nature. 395: 543-544. PMID 9783576 DOI: 10.1038/26850  0.349
1998 Picard D. Steroids tickle cells inside and out Nature. 392: 437-438. PMID 9548245 DOI: 10.1038/33014  0.392
1998 Liu JW, Picard D. Bioactive steroids as contaminants of the common carbon source galactose Fems Microbiology Letters. 159: 167-171. PMID 9503609 DOI: 10.1111/J.1574-6968.1998.Tb12856.X  0.338
1997 Picard D, Bunonet G, Liu W, Donzé O. Steroid-independent activation of steroid receptors in mammalian and yeast cells and in breast cancer Biochemical Society Transactions. 25: 597-602. PMID 9191163 DOI: 10.1042/Bst0250597  0.461
1997 Warth R, Briand PA, Picard D. Functional analysis of the yeast 40 kDa cyclophilin Cyp40 and its role for viability and steroid receptor regulation Biological Chemistry. 378: 381-391. PMID 9191025 DOI: 10.1515/Bchm.1997.378.5.381  0.377
1996 Louvion JF, Warth R, Picard D. Two eukaryote-specific regions of Hsp82 are dispensable for its viability and signal transduction functions in yeast Proceedings of the National Academy of Sciences of the United States of America. 93: 13937-13942. PMID 8943039 DOI: 10.1073/Pnas.93.24.13937  0.351
1996 Mattioni T, Mayer BJ, Picard D. Growth inhibition by Ab1 requires an interplay of its SH2 and tyrosine kinase domains Febs Letters. 390: 170-174. PMID 8706852 DOI: 10.1016/0014-5793(96)00650-3  0.334
1996 Bunone G, Briand PA, Miksicek RJ, Picard D. Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation Embo Journal. 15: 2174-2183. PMID 8641283 DOI: 10.1002/J.1460-2075.1996.Tb00571.X  0.459
1995 Whitelaw ML, McGuire J, Picard D, Gustafsson JA, Poellinger L. Heat shock protein hsp90 regulates dioxin receptor function in vivo Proceedings of the National Academy of Sciences of the United States of America. 92: 4437-4441. PMID 7753824 DOI: 10.1073/PNAS.92.10.4437  0.346
1994 Fankhauser CP, Briand PA, Picard D. The hormone binding domain of the mineralocorticoid receptor can regulate heterologous activities in cis Biochemical and Biophysical Research Communications. 200: 195-201. PMID 8166687 DOI: 10.1006/bbrc.1994.1433  0.322
1994 Mattioni T, Louvion JF, Picard D. Regulation of protein activities by fusion to steroid binding domains Methods in Cell Biology. 43: 335-352. PMID 7823870 DOI: 10.1016/S0091-679X(08)60611-1  0.414
1994 Picard D. Regulation of protein function through expression of chimaeric proteins Current Opinion in Biotechnology. 5: 511-515. PMID 7765465 DOI: 10.1016/0958-1669(94)90066-3  0.406
1993 Scherrer LC, Picard D, Massa E, Harmon JM, Simons SS, Yamamoto KR, Pratt WB. Evidence that the hormone binding domain of steroid receptors confers hormonal control on chimeric proteins by determining their hormone-regulated binding to heat-shock protein 90. Biochemistry. 32: 5381-6. PMID 8499442 DOI: 10.1021/Bi00071A013  0.62
1993 Louvion JF, Havaux-Copf B, Picard D. Fusion of GAL4-VP16 to a steroid-binding domain provides a tool for gratuitous induction of galactose-responsive genes in yeast Gene. 131: 129-134. PMID 8370533 DOI: 10.1016/0378-1119(93)90681-R  0.419
1993 Jackson P, Baltimore D, Picard D. Hormone-conditional transformation by fusion proteins of c-Abl and its transforming variants Embo Journal. 12: 2809-2819. PMID 8334997 DOI: 10.1002/J.1460-2075.1993.Tb05942.X  0.387
1993 Picard D. Steroid-binding domains for regulating the functions of heterologous proteins in cis Trends in Cell Biology. 3: 278-280. DOI: 10.1016/0962-8924(93)90057-8  0.326
1991 Schena M, Picard D, Yamamoto KR. Vectors for constitutive and inducible gene expression in yeast. Methods in Enzymology. 194: 389-98. PMID 2005799 DOI: 10.1016/0076-6879(91)94029-C  0.576
1991 Superti-Furga G, Bergers G, Picard D, Busslinger M. Hormone-dependent transcriptional regulation and cellular transformation by Fos-steroid receptor fusion proteins Proceedings of the National Academy of Sciences of the United States of America. 88: 5114-5118. PMID 1711219 DOI: 10.1073/Pnas.88.12.5114  0.312
1990 Picard D, Khursheed B, Garabedian MJ, Fortin MG, Lindquist S, Yamamoto KR. Reduced levels of hsp90 compromise steroid receptor action in vivo. Nature. 348: 166-8. PMID 2234079 DOI: 10.1038/348166A0  0.714
1990 Picard D, Schena M, Yamamoto KR. An inducible expression vector for both fission and budding yeast. Gene. 86: 257-61. PMID 2108906 DOI: 10.1016/0378-1119(90)90287-2  0.537
1990 Picard D, Kumar V, Chambon P, Yamamoto KR. Signal transduction by steroid hormones: nuclear localization is differentially regulated in estrogen and glucocorticoid receptors. Cell Regulation. 1: 291-9. PMID 2100202 DOI: 10.1091/Mbc.1.3.291  0.58
1989 Eilers M, Picard D, Yamamoto KR, Bishop JM. Chimaeras of myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells. Nature. 340: 66-8. PMID 2662015 DOI: 10.1038/340066a0  0.578
1988 Yamamoto KR, Godowski PJ, Picard D. Ligand-regulated nonspecific inactivation of receptor function: A versatile mechanism for signal transduction Cold Spring Harbor Symposia On Quantitative Biology. 53: 803-811. PMID 3076098 DOI: 10.1101/Sqb.1988.053.01.091  0.541
1988 Godowski PJ, Picard D, Yamamoto KR. Signal transduction and transcriptional regulation by glucocorticoid receptor-LexA fusion proteins Science. 241: 812-816. PMID 3043662 DOI: 10.1126/Science.3043662  0.631
1988 Picard D, Salser SJ, Yamamoto KR. A movable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor. Cell. 54: 1073-80. PMID 2843290 DOI: 10.1016/0092-8674(88)90122-5  0.597
1986 Klein S, Gerster T, Picard D, Radbruch A, Schaffner W. Evidence for transient requirement of the IgH enhancer. Nucleic Acids Research. 13: 8901-12. PMID 3936022 DOI: 10.1093/Nar/13.24.8901  0.558
1985 Picard D, Schaffner W. Cell-type preference of immunoglobulin kappa and lambda gene promoters. The Embo Journal. 4: 2831-2838. DOI: 10.1002/J.1460-2075.1985.Tb04011.X  0.546
1983 Picard D, Schaffner W. Correct transcription of a cloned mouse immunoglobulin gene in vivo. Proceedings of the National Academy of Sciences of the United States of America. 80: 417-21. PMID 6300842 DOI: 10.1073/Pnas.80.2.417  0.545
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