Manfred Grabner, PhD - Publications

Innsbruck Medical University, Innsbruck, Tirol, Austria 
Calcium Channels

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Dayal A, Perni S, Franzini-Armstrong C, Beam KG, Grabner M. The distal C terminus of the dihydropyridine receptor β subunit is essential for tetrad formation in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 119: e2201136119. PMID 35507876 DOI: 10.1073/pnas.2201136119  0.612
2021 Dayal A, Fernández-Quintero ML, Liedl KR, Grabner M. Pore mutation N617D in the skeletal muscle DHPR blocks Ca influx due to atypical high-affinity Ca binding. Elife. 10. PMID 34061024 DOI: 10.7554/eLife.63435  0.625
2021 Myers JH, Denman K, DuPont C, Hawash AA, Novak KR, Koesters A, Grabner M, Dayal A, Voss AA, Rich MM. The mechanism underlying transient weakness in myotonia congenita. Elife. 10. PMID 33904400 DOI: 10.7554/eLife.65691  0.609
2020 Idoux R, Fuster C, Jacquemond V, Dayal A, Grabner M, Charnet P, Allard B. Divalent cations permeation in a Ca non-conducting skeletal muscle dihydropyridine receptor mouse model. Cell Calcium. 91: 102256. PMID 32866694 DOI: 10.1016/J.Ceca.2020.102256  0.688
2019 Dayal A, Ng SFJ, Grabner M. Ca-activated Cl channel TMEM16A/ANO1 identified in zebrafish skeletal muscle is crucial for action potential acceleration. Nature Communications. 10: 115. PMID 30631052 DOI: 10.1038/S41467-018-07918-Z  0.654
2018 Kaplan MM, Sultana N, Benedetti A, Obermair GJ, Linde NF, Papadopoulos S, Dayal A, Grabner M, Flucher BE. Calcium Influx and Release Cooperatively Regulate AChR Patterning and Motor Axon Outgrowth during Neuromuscular Junction Formation. Cell Reports. 23: 3891-3904. PMID 29949772 DOI: 10.1016/J.Celrep.2018.05.085  0.597
2017 Dayal A, Schrötter K, Pan Y, Föhr K, Melzer W, Grabner M. The Ca(2+) influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance. Nature Communications. 8: 475. PMID 28883413 DOI: 10.1038/S41467-017-00629-X  0.682
2016 Schrötter K, Dayal A, Grabner M. The mammalian skeletal muscle DHPR has larger Ca(2+) conductance and is phylogenetically ancient to the early ray-finned fish sterlet (Acipenser ruthenus). Cell Calcium. PMID 27793347 DOI: 10.1016/J.Ceca.2016.10.002  0.679
2015 Josephine Ng SF, Dayal A, Grabner M. The Calcium-Activated Chloride Channel in Zebrafish Skeletal Muscle is Activated during Excitation-Contraction Coupling Biophysical Journal. 108: 420a. DOI: 10.1016/J.Bpj.2014.11.2301  0.682
2014 Dayal A, Schrötter K, Melzer W, Schwarzer C, Grabner M. The DHPR Calcium Current in Mammalian Skeletal Muscle: Physiological Necessity or Tolerated Evolutionary Remnant? Biophysical Journal. 106: 126a. DOI: 10.1016/J.Bpj.2013.11.748  0.652
2013 Dayal A, Bhat V, Franzini-Armstrong C, Grabner M. Domain cooperativity in the β1a subunit is essential for dihydropyridine receptor voltage sensing in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 110: 7488-93. PMID 23589859 DOI: 10.1073/Pnas.1301087110  0.614
2011 Bhat VK, Dayal A, Grabner M. Regions of the DHPRβ1A Subunit Responsible for DHPR Voltage-Sensing in Skeletal Muscle Excitation-Contraction Coupling Biophysical Journal. 100: 591a-592a. DOI: 10.1016/J.Bpj.2010.12.3411  0.567
2010 Grabner M, Dayal A. Crosstalk via the Sarcoplasmic Gap: The DHPR-RyR Interaction. Current Topics in Membranes. 66: 115-38. PMID 22353478 DOI: 10.1016/S1063-5823(10)66006-1  0.687
2010 Pirone A, Schredelseker J, Tuluc P, Gravino E, Fortunato G, Flucher BE, Carsana A, Salvatore F, Grabner M. Identification and functional characterization of malignant hyperthermia mutation T1354S in the outer pore of the Cavalpha1S-subunit. American Journal of Physiology. Cell Physiology. 299: C1345-54. PMID 20861472 DOI: 10.1152/Ajpcell.00008.2010  0.76
2010 Dayal A, Schredelseker J, Franzini-Armstrong C, Grabner M. Skeletal muscle excitation-contraction coupling is independent of a conserved heptad repeat motif in the C-terminus of the DHPRbeta(1a) subunit. Cell Calcium. 47: 500-6. PMID 20451250 DOI: 10.1016/J.Ceca.2010.04.003  0.802
2010 Schredelseker J, Shrivastav M, Dayal A, Grabner M. Non-Ca2+-conducting Ca2+ channels in fish skeletal muscle excitation-contraction coupling. Proceedings of the National Academy of Sciences of the United States of America. 107: 5658-63. PMID 20212109 DOI: 10.1073/Pnas.0912153107  0.797
2009 Schredelseker J, Dayal A, Schwerte T, Franzini-Armstrong C, Grabner M. Proper restoration of excitation-contraction coupling in the dihydropyridine receptor beta1-null zebrafish relaxed is an exclusive function of the beta1a subunit. The Journal of Biological Chemistry. 284: 1242-51. PMID 19008220 DOI: 10.1074/Jbc.M807767200  0.777
2008 Bannister RA, Grabner M, Beam KG. The alpha(1S) III-IV loop influences 1,4-dihydropyridine receptor gating but is not directly involved in excitation-contraction coupling interactions with the type 1 ryanodine receptor. The Journal of Biological Chemistry. 283: 23217-23. PMID 18556650 DOI: 10.1074/Jbc.M804312200  0.773
2005 Schredelseker J, Di Biase V, Obermair GJ, Felder ET, Flucher BE, Franzini-Armstrong C, Grabner M. The beta 1a subunit is essential for the assembly of dihydropyridine-receptor arrays in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 102: 17219-24. PMID 16286639 DOI: 10.1073/Pnas.0508710102  0.753
2005 Flucher BE, Obermair GJ, Tuluc P, Schredelseker J, Kern G, Grabner M. The role of auxiliary dihydropyridine receptor subunits in muscle. Journal of Muscle Research and Cell Motility. 26: 1-6. PMID 16088377 DOI: 10.1007/S10974-005-9000-2  0.778
2005 Obermair GJ, Kugler G, Baumgartner S, Tuluc P, Grabner M, Flucher BE. The Ca2+ channel alpha2delta-1 subunit determines Ca2+ current kinetics in skeletal muscle but not targeting of alpha1S or excitation-contraction coupling. The Journal of Biological Chemistry. 280: 2229-37. PMID 15536090 DOI: 10.1074/Jbc.M411501200  0.573
2004 Takekura H, Paolini C, Franzini-Armstrong C, Kugler G, Grabner M, Flucher BE. Differential contribution of skeletal and cardiac II-III loop sequences to the assembly of dihydropyridine-receptor arrays in skeletal muscle. Molecular Biology of the Cell. 15: 5408-19. PMID 15385628 DOI: 10.1091/Mbc.E04-05-0414  0.463
2004 Weiss RG, O'Connell KM, Flucher BE, Allen PD, Grabner M, Dirksen RT. Functional analysis of the R1086H malignant hyperthermia mutation in the DHPR reveals an unexpected influence of the III-IV loop on skeletal muscle EC coupling. American Journal of Physiology. Cell Physiology. 287: C1094-102. PMID 15201141 DOI: 10.1152/Ajpcell.00173.2004  0.687
2003 Kasielke N, Obermair GJ, Kugler G, Grabner M, Flucher BE. Cardiac-type EC-coupling in dysgenic myotubes restored with Ca2+ channel subunit isoforms alpha1C and alpha1D does not correlate with current density. Biophysical Journal. 84: 3816-28. PMID 12770887 DOI: 10.1016/S0006-3495(03)75109-1  0.54
2003 Melliti K, Grabner M, Seabrook GR. The familial hemiplegic migraine mutation R192Q reduces G-protein-mediated inhibition of P/Q-type (Ca(V)2.1) calcium channels expressed in human embryonic kidney cells. The Journal of Physiology. 546: 337-47. PMID 12527722 DOI: 10.1113/Jphysiol.2002.026716  0.457
2002 Wappl E, Koschak A, Poteser M, Sinnegger MJ, Walter D, Eberhart A, Groschner K, Glossmann H, Kraus RL, Grabner M, Striessnig J. Functional consequences of P/Q-type Ca2+ channel Cav2.1 missense mutations associated with episodic ataxia type 2 and progressive ataxia. The Journal of Biological Chemistry. 277: 6960-6. PMID 11742003 DOI: 10.1074/Jbc.M110948200  0.516
2001 Wilkens CM, Grabner M, Beam KG. Potentiation of the cardiac L-type Ca(2+) channel (alpha(1C)) by dihydropyridine agonist and strong depolarization occur via distinct mechanisms. The Journal of General Physiology. 118: 495-508. PMID 11696608 DOI: 10.1085/Jgp.118.5.495  0.777
2001 Lorenzon NM, Grabner M, Suda N, Beam KG. Structure and targeting of RyR1: implications from fusion of green fluorescent protein at the amino-terminal. Archives of Biochemistry and Biophysics. 388: 13-7. PMID 11361129 DOI: 10.1006/Abbi.2000.2263  0.616
2001 Wilkens CM, Kasielke N, Flucher BE, Beam KG, Grabner M. Excitation-contraction coupling is unaffected by drastic alteration of the sequence surrounding residues L720-L764 of the alpha 1S II-III loop. Proceedings of the National Academy of Sciences of the United States of America. 98: 5892-7. PMID 11320225 DOI: 10.1073/Pnas.101618098  0.777
2001 Koschak A, Reimer D, Huber I, Grabner M, Glossmann H, Engel J, Striessnig J. alpha 1D (Cav1.3) subunits can form l-type Ca2+ channels activating at negative voltages. The Journal of Biological Chemistry. 276: 22100-6. PMID 11285265 DOI: 10.1074/Jbc.M101469200  0.516
1999 Grabner M, Dirksen RT, Suda N, Beam KG. The II-III loop of the skeletal muscle dihydropyridine receptor is responsible for the Bi-directional coupling with the ryanodine receptor. The Journal of Biological Chemistry. 274: 21913-9. PMID 10419512 DOI: 10.1074/Jbc.274.31.21913  0.773
1998 Kraus RL, Hering S, Grabner M, Ostler D, Striessnig J. Molecular mechanism of diltiazem interaction with L-type Ca2+ channels. The Journal of Biological Chemistry. 273: 27205-12. PMID 9765241 DOI: 10.1074/Jbc.273.42.27205  0.501
1998 Mitterdorfer J, Grabner M, Kraus RL, Hering S, Prinz H, Glossmann H, Striessnig J. Molecular basis of drug interaction with L-type Ca2+ channels. Journal of Bioenergetics and Biomembranes. 30: 319-34. PMID 9758329 DOI: 10.1023/A:1021933504909  0.654
1998 Striessnig J, Grabner M, Mitterdorfer J, Hering S, Sinnegger MJ, Glossmann H. Structural basis of drug binding to L Ca2+ channels. Trends in Pharmacological Sciences. 19: 108-15. PMID 9584627 DOI: 10.1016/S0165-6147(98)01171-7  0.658
1998 Grabner M, Dirksen RT, Beam KG. Tagging with green fluorescent protein reveals a distinct subcellular distribution of L-type and non-L-type Ca2+ channels expressed in dysgenic myotubes. Proceedings of the National Academy of Sciences of the United States of America. 95: 1903-8. PMID 9465115 DOI: 10.1073/Pnas.95.4.1903  0.772
1997 Sinnegger MJ, Wang Z, Grabner M, Hering S, Striessnig J, Glossmann H, Mitterdorfer J. Nine L-type amino acid residues confer full 1,4-dihydropyridine sensitivity to the neuronal calcium channel alpha1A subunit. Role of L-type Met1188. The Journal of Biological Chemistry. 272: 27686-93. PMID 9346909 DOI: 10.1074/Jbc.272.44.27686  0.642
1996 Mitterdorfer J, Wang Z, Sinnegger MJ, Hering S, Striessnig J, Grabner M, Glossmann H. Two amino acid residues in the IIIS5 segment of L-type calcium channels differentially contribute to 1,4-dihydropyridine sensitivity. The Journal of Biological Chemistry. 271: 30330-5. PMID 8939992 DOI: 10.1074/Jbc.271.48.30330  0.653
1996 Pichler M, Wang Z, Grabner-Weiss C, Reimer D, Hering S, Grabner M, Glossmann H, Striessnig J. Block of P/Q-type calcium channels by therapeutic concentrations of aminoglycoside antibiotics. Biochemistry. 35: 14659-64. PMID 8931565 DOI: 10.1021/Bi961657T  0.633
1996 Hering S, Aczél S, Grabner M, Döring F, Berjukow S, Mitterdorfer J, Sinnegger MJ, Striessnig J, Degtiar VE, Wang Z, Glossmann H. Transfer of high sensitivity for benzothiazepines from L-type to class A (BI) calcium channels. The Journal of Biological Chemistry. 271: 24471-5. PMID 8798706 DOI: 10.1074/Jbc.271.40.24471  0.63
1996 Berjukow S, Döring F, Froschmayr M, Grabner M, Glossmann H, Hering S. Endogenous calcium channels in human embryonic kidney (HEK293) cells. British Journal of Pharmacology. 118: 748-54. PMID 8762103 DOI: 10.1111/J.1476-5381.1996.Tb15463.X  0.585
1996 Mitterdorfer J, Froschmayr M, Grabner M, Moebius FF, Glossmann H, Striessnig J. Identification of PK-A phosphorylation sites in the carboxyl terminus of L-type calcium channel alpha 1 subunits. Biochemistry. 35: 9400-6. PMID 8755718 DOI: 10.1021/Bi960683O  0.516
1996 Kraus R, Reichl B, Kimball SD, Grabner M, Murphy BJ, Catterall WA, Striessnig J. Identification of benz(othi)azepine-binding regions within L-type calcium channel alpha1 subunits. The Journal of Biological Chemistry. 271: 20113-8. PMID 8702733 DOI: 10.1074/jbc.271.33.20113  0.368
1996 Döring F, Degtiar VE, Grabner M, Striessnig J, Hering S, Glossman H. Transfer of L-type calcium channel IVS6 segment increases phenylalkylamine sensitivity of alpha1A. The Journal of Biological Chemistry. 271: 11745-9. PMID 8662622 DOI: 10.1074/Jbc.271.20.11745  0.494
1996 Grabner M, Wang Z, Hering S, Striessnig J, Glossmann H. Transfer of 1,4-dihydropyridine sensitivity from L-type to class A (BI) calcium channels. Neuron. 16: 207-18. PMID 8562085 DOI: 10.1016/S0896-6273(00)80037-9  0.679
1995 Hanner M, Moebius FF, Weber F, Grabner M, Striessnig J, Glossmann H. Phenylalkylamine Ca2+ antagonist binding protein. Molecular cloning, tissue distribution, and heterologous expression. The Journal of Biological Chemistry. 270: 7551-7. PMID 7706302 DOI: 10.1074/Jbc.270.13.7551  0.516
1995 Mitterdorfer J, Sinnegger MJ, Grabner M, Striessnig J, Glossmann H. Coordination of Ca2+ by the pore region glutamates is essential for high-affinity dihydropyridine binding to the cardiac Ca2+ channel alpha 1 subunit. Biochemistry. 34: 9350-5. PMID 7626604 DOI: 10.1021/Bi00029A010  0.516
1995 Wang Z, Grabner M, Berjukow S, Savchenko A, Glossmann H, Hering S. Chimeric L-type Ca2+ channels expressed in Xenopus laevis oocytes reveal role of repeats III and IV in activation gating. The Journal of Physiology. 486: 131-7. PMID 7562629 DOI: 10.1113/Jphysiol.1995.Sp020797  0.638
1994 Grabner M, Bachmann A, Rosenthal F, Striessnig J, Schultz C, Tautz D, Glossmann H. Insect calcium channels. Molecular cloning of an alpha 1-subunit from housefly (Musca domestica) muscle. Febs Letters. 339: 189-94. PMID 8313972 DOI: 10.1016/0014-5793(94)80413-3  0.638
1994 Grabner M, Wang Z, Mitterdorfer J, Rosenthal F, Charnet P, Savchenko A, Hering S, Ren D, Hall LM, Glossmann H. Cloning and functional expression of a neuronal calcium channel beta subunit from house fly (Musca domestica). The Journal of Biological Chemistry. 269: 23668-74. PMID 8089136  0.517
1994 Mitterdorfer J, Froschmayr M, Grabner M, Striessnig J, Glossmann H. Calcium channels: the beta-subunit increases the affinity of dihydropyridine and Ca2+ binding sites of the alpha 1-subunit. Febs Letters. 352: 141-5. PMID 7925963 DOI: 10.1016/0014-5793(94)00938-4  0.516
1991 Grabner M, Friedrich K, Knaus HG, Striessnig J, Scheffauer F, Staudinger R, Koch WJ, Schwartz A, Glossmann H. Calcium channels from Cyprinus carpio skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 88: 727-31. PMID 1846962 DOI: 10.1073/Pnas.88.3.727  0.654
1988 Striessnig J, Meusburger E, Grabner M, Knaus HG, Glossmann H, Kaiser J, Schölkens B, Becker R, Linz W, Henning R. Evidence for a distinct Ca2+ antagonist receptor for the novel benzothiazinone compound HOE 166. Naunyn-Schmiedeberg's Archives of Pharmacology. 337: 331-40. PMID 2839780 DOI: 10.1007/Bf00168847  0.516
1987 Striessnig J, Knaus HG, Grabner M, Moosburger K, Seitz W, Lietz H, Glossmann H. Photoaffinity labelling of the phenylalkylamine receptor of the skeletal muscle transverse-tubule calcium channel. Febs Letters. 212: 247-53. PMID 2434359 DOI: 10.1016/0014-5793(87)81354-6  0.516
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