Jau-Nian Chen, Ph.D. - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Development of Cardiovascular System, Zebrafish

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Xu Q, Dupper NJ, Smaligo AJ, Fan YC, Cai L, Wang Z, Langenbacher AD, Chen JN, Kwon O. Catalytic Enantioselective Synthesis of Guvacine Derivatives through [4 + 2] Annulations of Imines with α-Methylallenoates. Organic Letters. PMID 30246538 DOI: 10.1021/acs.orglett.8b02489  1
2018 Ding Y, Ma J, Langenbacher AD, Baek KI, Lee J, Chang CC, Hsu JJ, Kulkarni RP, Belperio J, Shi W, Ranjbarvaziri S, Ardehali R, Tintut Y, Demer LL, Chen JN, et al. Multiscale light-sheet for rapid imaging of cardiopulmonary system. Jci Insight. 3. PMID 30135307 DOI: 10.1172/jci.insight.121396  1
2018 Ziyad S, Riordan JD, Cavanaugh AM, Su T, Hernandez GE, Hilfenhaus G, Morselli M, Huynh K, Wang K, Chen JN, Dupuy AJ, Iruela-Arispe ML. A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis. Cell Reports. 22: 1211-1224. PMID 29386109 DOI: 10.1016/j.celrep.2018.01.017  0.56
2017 Shimizu H, Langenbacher AD, Huang J, Wang K, Otto G, Geisler R, Wang Y, Chen JN. The Calcineurin-FoxO-MuRF1 signaling pathway regulates myofibril integrity in cardiomyocytes. Elife. 6. PMID 28826496 DOI: 10.7554/eLife.27955  1
2016 Lu F, Langenbacher A, Chen JN. Tbx20 drives cardiac progenitor formation and cardiomyocyte proliferation in zebrafish. Developmental Biology. PMID 27940156 DOI: 10.1016/j.ydbio.2016.12.009  0.68
2016 Berchtold MW, Zacharias T, Kulej K, Wang K, Torggler R, Jespersen T, Chen JN, Larsen MR, La Cour JM. The Arrhythmogenic Calmodulin Mutation D129G Dysregulates Cell Growth, Calmodulin-dependent Kinase II Activity and Cardiac Function in Zebrafish. The Journal of Biological Chemistry. PMID 27815504 DOI: 10.1074/jbc.M116.758680  0.4
2016 Lu F, Langenbacher AD, Chen JN. Transcriptional Regulation of Heart Development in Zebrafish. Journal of Cardiovascular Development and Disease. 3. PMID 27148546 DOI: 10.3390/jcdd3020014  1
2016 Xu F, Huang J, He Z, Chen J, Tang X, Song Z, Guo Q, Huang C. Microglial Polarization Dynamics in Dorsal Spinal Cord in the Early Stages Following Chronic Sciatic Nerve Damage. Neuroscience Letters. PMID 26820376 DOI: 10.1016/j.neulet.2016.01.038  0.56
2016 Huang H, Jiang X, Wang J, Li Y, Song CX, Chen P, Li S, Gurbuxani S, Arnovitz S, Wang Y, Weng H, Neilly MB, He C, Li Z, Chen J. Identification of MLL-fusion/MYC⊣miR-26⊣TET1 signaling circuit in MLL-rearranged leukemia. Cancer Letters. PMID 26791235 DOI: 10.1016/j.canlet.2015.12.032  0.4
2016 Chen J, Cai J, Huang X, Yi T, Wang K, Pan S. Detection of bacterial concentration variations based on dielectric magnetic flux Food Chemistry. 192: 642-646. DOI: 10.1016/j.foodchem.2015.07.048  0.4
2016 Shen B, Chen J, Cai J. Removal of elemental mercury by KI-impregnated clay Frontiers of Environmental Science and Engineering. 10: 236-243. DOI: 10.1007/s11783-014-0765-7  0.36
2015 Cavanaugh AM, Huang J, Chen JN. Two developmentally distinct populations of neural crest cells contribute to the zebrafish heart. Developmental Biology. 404: 103-12. PMID 26086691 DOI: 10.1016/j.ydbio.2015.06.002  1
2015 Shen ZC, Luo B, Chen JN, Chao Y, Shao CK, Liu QQ, Wang Y. High prevalence of the EBER variant EB-8m in endemic nasopharyngeal carcinomas. Plos One. 10: e0121420. PMID 25807550 DOI: 10.1371/journal.pone.0121420  0.4
2015 Shimizu H, Schredelseker J, Huang J, Lu K, Naghdi S, Lu F, Franklin S, Fiji HD, Wang K, Zhu H, Tian C, Lin B, Nakano H, Ehrlich A, Nakai J, ... ... Chen JN, et al. Mitochondrial Ca(2+) uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity. Elife. 4. PMID 25588501 DOI: 10.7554/eLife.04801  1
2014 Lin C, Yao E, Wang K, Nozawa Y, Shimizu H, Johnson JR, Chen JN, Krogan NJ, Chuang PT. Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling. Genes & Development. 28: 2547-63. PMID 25403183 DOI: 10.1101/gad.249425.114  1
2014 Li R, Beebe T, Jen N, Yu F, Takabe W, Harrison M, Cao H, Lee J, Yang H, Han P, Wang K, Shimizu H, Chen J, Lien CL, Chi NC, et al. Shear stress-activated Wnt-angiopoietin-2 signaling recapitulates vascular repair in zebrafish embryos. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 2268-75. PMID 25147335 DOI: 10.1161/ATVBAHA.114.303345  1
2014 Zhang Y, Shimizu H, Siu KL, Mahajan A, Chen JN, Cai H. NADPH oxidase 4 induces cardiac arrhythmic phenotype in zebrafish. The Journal of Biological Chemistry. 289: 23200-8. PMID 24962575 DOI: 10.1074/jbc.M114.587196  1
2014 Schredelseker J, Paz A, López CJ, Altenbach C, Leung CS, Drexler MK, Chen JN, Hubbell WL, Abramson J. High resolution structure and double electron-electron resonance of the zebrafish voltage-dependent anion channel 2 reveal an oligomeric population. The Journal of Biological Chemistry. 289: 12566-77. PMID 24627492 DOI: 10.1074/jbc.M113.497438  1
2014 Jin Y, Chen JN, Feng ZY, Zhang ZG, Fan WZ, Wang Y, Li JP. OPN and αvβ3 expression are predictors of disease severity and worse prognosis in hepatocellular carcinoma. Plos One. 9: e87930. PMID 24498405 DOI: 10.1371/journal.pone.0087930  0.4
2013 Monte E, Mouillesseaux K, Chen H, Kimball T, Ren S, Wang Y, Chen JN, Vondriska TM, Franklin S. Systems proteomics of cardiac chromatin identifies nucleolin as a regulator of growth and cellular plasticity in cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. 305: H1624-38. PMID 24077883 DOI: 10.1152/ajpheart.00529.2013  1
2013 Foster WH, Langenbacher A, Gao C, Chen J, Wang Y. Nuclear phosphatase PPM1G in cellular survival and neural development Developmental Dynamics. 242: 1101-1109. PMID 23723158 DOI: 10.1002/dvdy.23990  1
2012 Van Handel B, Montel-Hagen A, Sasidharan R, Nakano H, Ferrari R, Boogerd CJ, Schredelseker J, Wang Y, Hunter S, Org T, Zhou J, Li X, Pellegrini M, Chen JN, Orkin SH, et al. Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium. Cell. 150: 590-605. PMID 22863011 DOI: 10.1016/j.cell.2012.06.026  1
2012 Langenbacher AD, Huang J, Chen Y, Chen JN. Sodium pump activity in the yolk syncytial layer regulates zebrafish heart tube morphogenesis. Developmental Biology. 362: 263-70. PMID 22182522 DOI: 10.1016/j.ydbio.2011.12.004  1
2011 Mouillesseaux K, Chen JN. Mutation in utp15 disrupts vascular patterning in a p53-dependent manner in zebrafish embryos. Plos One. 6: e25013. PMID 21949834 DOI: 10.1371/journal.pone.0025013  1
2011 Langenbacher AD, Nguyen CT, Cavanaugh AM, Huang J, Lu F, Chen JN. The PAF1 complex differentially regulates cardiomyocyte specification. Developmental Biology. 353: 19-28. PMID 21338598 DOI: 10.1016/j.ydbio.2011.02.011  1
2011 Choi J, Mouillesseaux K, Wang Z, Fiji HD, Kinderman SS, Otto GW, Geisler R, Kwon O, Chen JN. Aplexone targets the HMG-CoA reductase pathway and differentially regulates arteriovenous angiogenesis. Development (Cambridge, England). 138: 1173-81. PMID 21307094 DOI: 10.1242/dev.054049  1
2011 Sun H, Lu G, Ren S, Chen J, Wang Y. Catabolism of branched-chain amino acids in heart failure: Insights from genetic models Pediatric Cardiology. 32: 305-310. PMID 21210099 DOI: 10.1007/s00246-010-9856-9  1
2010 Yu F, Huang J, Adlerz K, Jadvar H, Hamdan MH, Chi N, Chen JN, Hsiai TK. Evolving cardiac conduction phenotypes in developing zebrafish larvae: implications to drug sensitivity. Zebrafish. 7: 325-31. PMID 20958244 DOI: 10.1089/zeb.2010.0658  1
2010 Nguyen CT, Langenbacher A, Hsieh M, Chen JN. The PAF1 complex component Leo1 is essential for cardiac and neural crest development in zebrafish. Developmental Biology. 341: 167-75. PMID 20178782 DOI: 10.1016/j.ydbio.2010.02.020  1
2010 Langenbacher AD, Chen JN. Regulation of vertebrate left-right axis development by calcium Handbook of Cell Signaling, 2/E. 2: 1885-1890. DOI: 10.1016/B978-0-12-374145-5.00230-8  1
2009 Wilson CW, Nguyen CT, Chen MH, Yang JH, Gacayan R, Huang J, Chen JN, Chuang PT. Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis. Nature. 459: 98-102. PMID 19305393 DOI: 10.1038/nature07883  1
2009 Colantonio JR, Vermot J, Wu D, Langenbacher AD, Fraser S, Chen JN, Hill KL. The dynein regulatory complex is required for ciliary motility and otolith biogenesis in the inner ear. Nature. 457: 205-9. PMID 19043402 DOI: 10.1038/nature07520  1
2008 Nguyen CT, Lu Q, Wang Y, Chen JN. Zebrafish as a model for cardiovascular development and disease. Drug Discovery Today. Disease Models. 5: 135-140. PMID 22275951 DOI: 10.1016/j.ddmod.2009.02.003  1
2008 Langenbacher A, Chen JN. Calcium signaling: a common thread in vertebrate left-right axis development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 3491-6. PMID 18792114 DOI: 10.1002/dvdy.21704  1
2008 Xie Y, Ottolia M, John SA, Chen JN, Philipson KD. Conformational changes of a Ca2+-binding domain of the Na+/Ca2+ exchanger monitored by FRET in transgenic zebrafish heart. American Journal of Physiology. Cell Physiology. 295: C388-93. PMID 18550703 DOI: 10.1152/ajpcell.00178.2008  1
2007 Liu J, Fraser SD, Faloon PW, Rollins EL, Vom Berg J, Starovic-Subota O, Laliberte AL, Chen JN, Serluca FC, Childs SJ. A betaPix Pak2a signaling pathway regulates cerebral vascular stability in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 104: 13990-5. PMID 17573532 DOI: 10.1073/pnas.0700825104  1
2007 Shu X, Huang J, Dong Y, Choi J, Langenbacher A, Chen JN. Na,K-ATPase alpha2 and Ncx4a regulate zebrafish left-right patterning. Development (Cambridge, England). 134: 1921-30. PMID 17442698 DOI: 10.1242/dev.02851  1
2007 Lu G, Ren S, Korge P, Choi J, Dong Y, Weiss J, Koehler C, Chen JN, Wang Y. A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. Genes & Development. 21: 784-96. PMID 17374715 DOI: 10.1101/gad.1499107  1
2007 Choi J, Dong L, Ahn J, Dao D, Hammerschmidt M, Chen JN. FoxH1 negatively modulates flk1 gene expression and vascular formation in zebrafish. Developmental Biology. 304: 735-44. PMID 17306248 DOI: 10.1016/j.ydbio.2007.01.023  1
2007 Cibrián-Uhalte E, Langenbacher A, Shu X, Chen JN, Abdelilah-Seyfried S. Involvement of zebrafish Na+,K+ ATPase in myocardial cell junction maintenance. The Journal of Cell Biology. 176: 223-30. PMID 17227894 DOI: 10.1083/jcb.200606116  1
2006 Mably JD, Chuang LP, Serluca FC, Mohideen MA, Chen JN, Fishman MC. santa and valentine pattern concentric growth of cardiac myocardium in the zebrafish. Development (Cambridge, England). 133: 3139-46. PMID 16873582 DOI: 10.1242/dev.02469  1
2006 Kim HJ, Sumanas S, Palencia-Desai S, Dong Y, Chen JN, Lin S. Genetic analysis of early endocrine pancreas formation in zebrafish. Molecular Endocrinology (Baltimore, Md.). 20: 194-203. PMID 16099813 DOI: 10.1210/me.2005-0189  1
2005 Chen JN, Cowan DB, Mably JD. Cardiogenesis and the regulation of cardiac-specific gene expression. Heart Failure Clinics. 1: 157-70. PMID 17386843 DOI: 10.1016/j.hfc.2005.03.002  1
2005 Langenbacher AD, Dong Y, Shu X, Choi J, Nicoll DA, Goldhaber JI, Philipson KD, Chen JN. Mutation in sodium-calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 102: 17699-704. PMID 16314583 DOI: 10.1073/pnas.0502679102  1
2005 Jin SW, Beis D, Mitchell T, Chen JN, Stainier DY. Cellular and molecular analyses of vascular tube and lumen formation in zebrafish. Development (Cambridge, England). 132: 5199-209. PMID 16251212 DOI: 10.1242/dev.02087  1
2005 Beis D, Bartman T, Jin SW, Scott IC, D'Amico LA, Ober EA, Verkade H, Frantsve J, Field HA, Wehman A, Baier H, Tallafuss A, Bally-Cuif L, Chen JN, Stainier DY, et al. Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development. Development (Cambridge, England). 132: 4193-204. PMID 16107477 DOI: 10.1242/dev.01970  1
2005 Huang H, Zhang B, Hartenstein PA, Chen JN, Lin S. NXT2 is required for embryonic heart development in zebrafish. Bmc Developmental Biology. 5: 7. PMID 15790397 DOI: 10.1186/1471-213X-5-7  1
2003 Mably JD, Mohideen MA, Burns CG, Chen JN, Fishman MC. heart of glass regulates the concentric growth of the heart in zebrafish. Current Biology : Cb. 13: 2138-47. PMID 14680629 DOI: 10.1016/j.cub.2003.11.055  1
2003 Shu X, Cheng K, Patel N, Chen F, Joseph E, Tsai HJ, Chen JN. Na,K-ATPase is essential for embryonic heart development in the zebrafish. Development (Cambridge, England). 130: 6165-73. PMID 14602677 DOI: 10.1242/dev.00844  1
2003 Cross LM, Cook MA, Lin S, Chen JN, Rubinstein AL. Rapid analysis of angiogenesis drugs in a live fluorescent zebrafish assay. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 911-2. PMID 12740225 DOI: 10.1161/01.ATV.0000068685.72914.7E  1
2002 Childs S, Chen JN, Garrity DM, Fishman MC. Patterning of angiogenesis in the zebrafish embryo. Development (Cambridge, England). 129: 973-82. PMID 11861480  1
2001 Chen JN, van Bebber F, Goldstein AM, Serluca FC, Jackson D, Childs S, Serbedzija G, Warren KS, Mably JD, Lindahl P, Mayer A, Haffter P, Fishman MC. Genetic steps to organ laterality in zebrafish. Comparative and Functional Genomics. 2: 60-8. PMID 18628903 DOI: 10.1002/cfg.74  1
2001 Peterson RT, Mably JD, Chen JN, Fishman MC. Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul. Current Biology : Cb. 11: 1481-91. PMID 11591315 DOI: 10.1016/S0960-9822(01)00482-1  1
2001 Chan J, Mably JD, Serluca FC, Chen JN, Goldstein NB, Thomas MC, Cleary JA, Brennan C, Fishman MC, Roberts TM. Morphogenesis of prechordal plate and notochord requires intact Eph/ephrin B signaling. Developmental Biology. 234: 470-82. PMID 11397014 DOI: 10.1006/dbio.2001.0281  1
2000 Chen JN, Fishman MC. Genetics of heart development. Trends in Genetics : Tig. 16: 383-8. PMID 10973066 DOI: 10.1016/S0168-9525(00)02075-8  1
2000 Chen JN, Fishman MC. Genetic dissection of heart development. Ernst Schering Research Foundation Workshop. 107-22. PMID 10943307  1
1998 Park M, Lewis C, Turbay D, Chung A, Chen JN, Evans S, Breitbart RE, Fishman MC, Izumo S, Bodmer R. Differential rescue of visceral and cardiac defects in Drosophila by vertebrate tinman-related genes. Proceedings of the National Academy of Sciences of the United States of America. 95: 9366-71. PMID 9689086 DOI: 10.1073/pnas.95.16.9366  1
1998 Serbedzija GN, Chen JN, Fishman MC. Regulation in the heart field of zebrafish. Development (Cambridge, England). 125: 1095-101. PMID 9463356  1
1997 Chen JN, van Eeden FJ, Warren KS, Chin A, Nüsslein-Volhard C, Haffter P, Fishman MC. Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development (Cambridge, England). 124: 4373-82. PMID 9334285  1
1997 Chin AJ, Chen JN, Weinberg ES. Bone morphogenetic protein-4 expression characterizes inductive boundaries in organs of developing zebrafish Development Genes and Evolution. 207: 107-114. DOI: 10.1007/s004270050097  1
1996 Chen JN, Fishman MC. Zebrafish tinman homolog demarcates the heart field and initiates myocardial differentiation. Development (Cambridge, England). 122: 3809-16. PMID 9012502  1
1996 Chen JN, Haffter P, Odenthal J, Vogelsang E, Brand M, van Eeden FJ, Furutani-Seiki M, Granato M, Hammerschmidt M, Heisenberg CP, Jiang YJ, Kane DA, Kelsh RN, Mullins MC, Nüsslein-Volhard C. Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development (Cambridge, England). 123: 293-302. PMID 9007249  1
1996 Stainier DY, Fouquet B, Chen JN, Warren KS, Weinstein BM, Meiler SE, Mohideen MA, Neuhauss SC, Solnica-Krezel L, Schier AF, Zwartkruis F, Stemple DL, Malicki J, Driever W, Fishman MC. Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development (Cambridge, England). 123: 285-92. PMID 9007248  1
1991 Murphy M, Chen JN, George DL. Establishment and characterization of a human leptomeningeal cell line. Journal of Neuroscience Research. 30: 475-83. PMID 1724784 DOI: 10.1002/jnr.490300304  0.36
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