Peter B. Bitterman - Publications

Affiliations: 
Microbiology, Immunology and Cancer Biology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Bioinformatics Biology, Genetics

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Beisang DJ, Smith K, Yang L, Benyumov A, Gilbertsen A, Herrera J, Lock E, Racila E, Forster C, Sandri BJ, Henke CA, Bitterman PB. Single-cell RNA sequencing reveals that lung mesenchymal progenitor cells in IPF exhibit pathological features early in their differentiation trajectory. Scientific Reports. 10: 11162. PMID 32636398 DOI: 10.1038/S41598-020-66630-5  0.388
2019 Sandri BJ, Masvidal L, Murie C, Bartish M, Avdulov S, Higgins L, Markowski T, Peterson M, Bergh J, Yang P, Rolny C, Limper AH, Griffin TJ, Bitterman PB, Wendt CH, et al. Distinct Cancer-Promoting Stromal Gene Expression Depending on Lung Function. American Journal of Respiratory and Critical Care Medicine. PMID 30742544 DOI: 10.1164/Rccm.201801-0080Oc  0.426
2019 Herrera J, Forster C, Pengo T, Montero A, Swift J, Schwartz MA, Henke CA, Bitterman PB. Registration of the extracellular matrix components constituting the fibroblastic focus in idiopathic pulmonary fibrosis. Jci Insight. 4. PMID 30626754 DOI: 10.1172/Jci.Insight.125185  0.333
2018 Wendt CH, Sandri BJ, Masvidal L, Murie C, Bartish M, Avdulov S, Higgins L, Markowski T, Peterson M, Bergh J, Yang P, Rolny C, Limper AH, Griffin TJ, Bitterman PB, et al. Chronic Obstructive Pulmonary Disease Phenotype Dictates Cancer-Promoting Stromal Gene Expression Programs. Annals of the American Thoracic Society. 15: S290-S291. PMID 30759015 DOI: 10.1513/Annalsats.201806-421Mg  0.387
2018 De A, Jacobson BA, Peterson MS, Stelzner ME, Jay-Dixon J, Kratzke MG, Patel MR, Bitterman PB, Kratzke RA. Inhibition of oncogenic cap-dependent translation by 4EGI-1 reduces growth, enhances chemosensitivity and alters genome-wide translation in non-small cell lung cancer. Cancer Gene Therapy. PMID 30420719 DOI: 10.1038/S41417-018-0058-6  0.664
2018 Sandri BJ, Kaplan A, Hodgson SW, Peterson M, Avdulov S, Higgins L, Markowski T, Yang P, Limper AH, Griffin TJ, Bitterman P, Lock EF, Wendt CH. Multi-Omic Molecular Profiling of Lung Cancer in Chronic Obstructive Pulmonary Disease. The European Respiratory Journal. PMID 29794131 DOI: 10.1183/13993003.02665-2017  0.374
2018 Zhou Y, Horowitz JC, Naba A, Ambalavanan N, Atabai K, Balestrini J, Bitterman PB, Corley RA, Ding BS, Engler AJ, Hansen KC, Hagood JS, Kheradmand F, Lin QS, Neptune E, et al. Extracellular matrix in lung development, homeostasis and disease. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29524630 DOI: 10.1016/J.Matbio.2018.03.005  0.418
2018 Herrera J, Henke CA, Bitterman PB. Extracellular matrix as a driver of progressive fibrosis. The Journal of Clinical Investigation. 128: 45-53. PMID 29293088 DOI: 10.1172/Jci93557  0.359
2017 Yang L, Herrera J, Gilbertsen AJ, Xia H, Smith K, Benyumov A, Bitterman PB, Henke CA. IL-8 Mediates Idiopathic Pulmonary Fibrosis Mesenchymal Progenitor Cell Fibrogenicity. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00200.2017. PMID 28860143 DOI: 10.1152/Ajplung.00200.2017  0.375
2017 Bhargava M, Viken K, Wang Q, Jagtap P, Bitterman P, Ingbar D, Wendt C. Bronchoalveolar Lavage Fluid Protein Expression in Acute Respiratory Distress Syndrome Provides Insights into Pathways Activated in Subjects with Different Outcomes. Scientific Reports. 7: 7464. PMID 28785034 DOI: 10.1038/S41598-017-07791-8  0.339
2017 Xia H, Gilbertsen A, Herrera J, Racila E, Smith K, Peterson M, Griffin T, Benyumov A, Yang L, Bitterman PB, Henke CA. Calcium-binding protein S100A4 confers mesenchymal progenitor cell fibrogenicity in idiopathic pulmonary fibrosis. The Journal of Clinical Investigation. PMID 28530639 DOI: 10.1172/Jci90832  0.443
2016 Bhargava M, Viken KJ, Dey S, Steinbach MS, Wu B, Jagtap PD, Higgins L, Panoskaltsis-Mortari A, Weisdorf DJ, Kumar V, Arora M, Bitterman PB, Ingbar DH, Wendt CH. Proteome Profiling in Lung Injury Following Hematopoietic Stem Cell Transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 27155584 DOI: 10.1016/J.Bbmt.2016.04.021  0.355
2016 Ochnik AM, Peterson MS, Avdulov SV, Oh AS, Bitterman PB, Yee D. Amplified in Breast Cancer Regulates Transcription and Translation in Breast Cancer Cells. Neoplasia (New York, N.Y.). 18: 100-10. PMID 26936396 DOI: 10.1016/J.Neo.2016.01.001  0.32
2015 Smith KA, Zhou B, Avdulov S, Benyumov A, Peterson M, Liu Y, Okon A, Hergert P, Braziunas J, Wagner CR, Borok Z, Bitterman PB. Transforming Growth Factor-β1 Induced Epithelial Mesenchymal Transition is blocked by a chemical antagonist of translation factor eIF4E. Scientific Reports. 5: 18233. PMID 26678431 DOI: 10.1038/Srep18233  0.4
2015 Bitterman PB. Rebuilding the injured lung. Annals of the American Thoracic Society. 12: S64-9. PMID 25830839 DOI: 10.1513/Annalsats.201411-529Mg  0.399
2015 Avdulov S, Herrera J, Smith K, Peterson M, Gomez-Garcia JR, Beadnell TC, Schwertfeger KL, Benyumov AO, Manivel JC, Li S, Bielinsky AK, Yee D, Bitterman PB, Polunovsky VA. eIF4E threshold levels differ in governing normal and neoplastic expansion of mammary stem and luminal progenitor cells. Cancer Research. 75: 687-97. PMID 25524901 DOI: 10.1158/0008-5472.Can-14-2571  0.33
2015 Bitterman PB, Polunovsky VA. eIF4E-mediated translational control of cancer incidence. Biochimica Et Biophysica Acta. 1849: 774-80. PMID 25263391 DOI: 10.1016/J.Bbagrm.2014.09.007  0.367
2015 Hu B, Liu J, Wu Z, Liu T, Ullenbruch MR, Ding L, Henke CA, Bitterman PB, Phan SH. Reemergence of hedgehog mediates epithelial-mesenchymal crosstalk in pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 52: 418-28. PMID 25140582 DOI: 10.1165/Rcmb.2014-0108Oc  0.454
2015 Sandri B, Limper A, Jagtap P, Avdulov S, Peterson M, Yang P, Larsson O, Murie C, Bitterman P, Griffin T, Higgins L, Markowski T, Wendt C. Large-scale quantitative proteomic analysis identifies pathways in COPD-associated lung cancer European Respiratory Journal. DOI: 10.1183/13993003.Congress-2015.Pa4270  0.36
2014 Chen EZ, Jacobson BA, Patel MR, Okon AM, Li S, Xiong K, Vaidya AJ, Bitterman PB, Wagner CR, Kratzke RA. Small-molecule inhibition of oncogenic eukaryotic protein translation in mesothelioma cells. Investigational New Drugs. 32: 598-603. PMID 24711125 DOI: 10.1007/S10637-014-0076-7  0.356
2014 Hohberger LA, Schroeder DR, Bartholmai BJ, Yang P, Wendt CH, Bitterman PB, Larsson O, Limper AH. Correlation of regional emphysema and lung cancer: a lung tissue research consortium-based study. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 639-45. PMID 24662456 DOI: 10.1097/Jto.0000000000000144  0.394
2014 Xia H, Bodempudi V, Benyumov A, Hergert P, Tank D, Herrera J, Braziunas J, Larsson O, Parker M, Rossi D, Smith K, Peterson M, Limper A, Jessurun J, Connett J, ... ... Bitterman PB, et al. Identification of a cell-of-origin for fibroblasts comprising the fibrotic reticulum in idiopathic pulmonary fibrosis. The American Journal of Pathology. 184: 1369-83. PMID 24631025 DOI: 10.1016/J.Ajpath.2014.01.012  0.453
2014 Parker MW, Rossi D, Peterson M, Smith K, Sikström K, White ES, Connett JE, Henke CA, Larsson O, Bitterman PB. Fibrotic extracellular matrix activates a profibrotic positive feedback loop. The Journal of Clinical Investigation. 124: 1622-35. PMID 24590289 DOI: 10.1172/Jci71386  0.412
2014 Avdulov SV, Gómez-García JR, Bitterman PB, Polunovsky VA. Translational Control of Cell Proliferation and Viability in Normal and Neoplastic Cells Springer Netherlands. 377-394. DOI: 10.1007/978-94-017-9078-9_18  0.386
2013 Bhargava M, Dey S, Becker T, Steinbach M, Wu B, Lee SM, Higgins L, Kumar V, Bitterman PB, Ingbar DH, Wendt CH. Protein expression profile of rat type two alveolar epithelial cells during hyperoxic stress and recovery. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L604-14. PMID 24014686 DOI: 10.1152/Ajplung.00079.2013  0.422
2013 Liu T, Ullenbruch M, Young Choi Y, Yu H, Ding L, Xaubet A, Pereda J, Feghali-Bostwick CA, Bitterman PB, Henke CA, Pardo A, Selman M, Phan SH. Telomerase and telomere length in pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 49: 260-8. PMID 23526226 DOI: 10.1165/Rcmb.2012-0514Oc  0.425
2013 Li S, Jia Y, Jacobson B, McCauley J, Kratzke R, Bitterman PB, Wagner CR. Treatment of breast and lung cancer cells with a N-7 benzyl guanosine monophosphate tryptamine phosphoramidate pronucleotide (4Ei-1) results in chemosensitization to gemcitabine and induced eIF4E proteasomal degradation. Molecular Pharmaceutics. 10: 523-31. PMID 23289910 DOI: 10.1021/Mp300699D  0.395
2013 Hu B, Wu Z, Hergert P, Henke CA, Bitterman PB, Phan SH. Regulation of myofibroblast differentiation by poly(ADP-ribose) polymerase 1. The American Journal of Pathology. 182: 71-83. PMID 23260200 DOI: 10.1016/J.Ajpath.2012.09.004  0.442
2012 Issaenko OA, Bitterman PB, Polunovsky VA, Dahlberg PS. Cap-dependent mRNA translation and the ubiquitin-proteasome system cooperate to promote ERBB2-dependent esophageal cancer phenotype. Cancer Gene Therapy. 19: 609-18. PMID 22767218 DOI: 10.1038/Cgt.2012.39  0.369
2012 Bitterman PB, Polunovsky VA. Attacking a nexus of the oncogenic circuitry by reversing aberrant eIF4F-mediated translation. Molecular Cancer Therapeutics. 11: 1051-61. PMID 22572598 DOI: 10.1158/1535-7163.Mct-11-0530  0.308
2012 Jia Y, Polunovsky V, Bitterman PB, Wagner CR. Cap-dependent translation initiation factor eIF4E: an emerging anticancer drug target. Medicinal Research Reviews. 32: 786-814. PMID 22495651 DOI: 10.1002/Med.21260  0.317
2012 Bitterman PB, Polunovsky VA. Translational control of cell fate: from integration of environmental signals to breaching anticancer defense. Cell Cycle (Georgetown, Tex.). 11: 1097-107. PMID 22356766 DOI: 10.4161/Cc.11.6.19610  0.347
2012 Benyumov AO, Hergert P, Herrera J, Peterson M, Henke C, Bitterman PB. A novel zebrafish embryo xenotransplantation model to study primary human fibroblast motility in health and disease. Zebrafish. 9: 38-43. PMID 22356695 DOI: 10.1089/Zeb.2011.0705  0.401
2012 Patel MR, Sadiq AA, Jay-Dixon J, Jirakulaporn T, Jacobson BA, Farassati F, Bitterman PB, Kratzke RA. Novel role of c-jun N-terminal kinase in regulating the initiation of cap-dependent translation. International Journal of Oncology. 40: 577-82. PMID 22076560 DOI: 10.3892/Ijo.2011.1252  0.437
2012 McCauley JA, Evenson K, Truitt M, Kratzke R, Polunovsky V, Ruggero D, BItterman P, D'Cunha J. Abstract 2347: Translational control and lung cancer: eIF4F activation promotes tumorigenesis in vivo Cancer Research. 72: 2347-2347. DOI: 10.1158/1538-7445.Am2012-2347  0.422
2011 Borok Z, Whitsett JA, Bitterman PB, Thannickal VJ, Kotton DN, Reynolds SD, Krasnow MA, Bianchi DW, Morrisey EE, Hogan BL, Kurie JM, Walker DC, Radisky DC, Nishimura SL, Violette SM, et al. Cell plasticity in lung injury and repair: report from an NHLBI workshop, April 19-20, 2010. Proceedings of the American Thoracic Society. 8: 215-22. PMID 21653526 DOI: 10.1513/pats.201012-067CB  0.316
2011 Zu T, Gibbens B, Doty NS, Gomes-Pereira M, Huguet A, Stone MD, Margolis J, Peterson M, Markowski TW, Ingram MA, Nan Z, Forster C, Low WC, Schoser B, Somia NV, ... ... Bitterman PB, et al. Non-ATG-initiated translation directed by microsatellite expansions. Proceedings of the National Academy of Sciences of the United States of America. 108: 260-5. PMID 21173221 DOI: 10.1073/Pnas.1013343108  0.334
2010 McCauley J, Jacobson B, Bitterman P, Kratzke R, D'Cunha J. Abstract 3148: Translational control of lung cancer: eIF4E over-expression is not sufficient to confer tumorigenicity to human bronchial epithelial cells Cancer Research. 70: 3148-3148. DOI: 10.1158/1538-7445.Am10-3148  0.451
2009 Kim YY, Von Weymarn L, Larsson O, Fan D, Underwood JM, Peterson MS, Hecht SS, Polunovsky VA, Bitterman PB. Eukaryotic initiation factor 4E binding protein family of proteins: sentinels at a translational control checkpoint in lung tumor defense. Cancer Research. 69: 8455-62. PMID 19843855 DOI: 10.1158/0008-5472.Can-09-1923  0.606
2009 Jacobson BA, De A, Kratzke MG, Patel MR, Jay-Dixon J, Whitson BA, Sadiq AA, Bitterman PB, Polunovsky VA, Kratzke RA. Activated 4E-BP1 represses tumourigenesis and IGF-I-mediated activation of the eIF4F complex in mesothelioma. British Journal of Cancer. 101: 424-31. PMID 19603014 DOI: 10.1038/Sj.Bjc.6605184  0.594
2009 Fan D, Bitterman PB, Larsson O. Regulatory element identification in subsets of transcripts: comparison and integration of current computational methods. Rna (New York, N.Y.). 15: 1469-82. PMID 19553345 DOI: 10.1261/Rna.1617009  0.52
2009 Ghosh B, Benyumov AO, Ghosh P, Jia Y, Avdulov S, Dahlberg PS, Peterson M, Smith K, Polunovsky VA, Bitterman PB, Wagner CR. Nontoxic chemical interdiction of the epithelial-to-mesenchymal transition by targeting cap-dependent translation. Acs Chemical Biology. 4: 367-77. PMID 19351181 DOI: 10.1021/Cb9000475  0.358
2008 Larsson O, Diebold D, Fan D, Peterson M, Nho RS, Bitterman PB, Henke CA. Fibrotic myofibroblasts manifest genome-wide derangements of translational control. Plos One. 3: e3220. PMID 18795102 DOI: 10.1371/Journal.Pone.0003220  0.575
2008 Xia H, Diebold D, Nho R, Perlman D, Kleidon J, Kahm J, Avdulov S, Peterson M, Nerva J, Bitterman P, Henke C. Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis. The Journal of Experimental Medicine. 205: 1659-72. PMID 18541712 DOI: 10.1084/Jem.20080001  0.434
2008 Ghosh P, Cheng J, Chou TF, Jia Y, Avdulov S, Bitterman PB, Polunovsky VA, Wagner CR. Expression, purification and characterization of recombinant mouse translation initiation factor eIF4E as a dihydrofolate reductase (DHFR) fusion protein. Protein Expression and Purification. 60: 132-9. PMID 18479935 DOI: 10.1016/J.Pep.2008.03.024  0.327
2008 Vlasova IA, Tahoe NM, Fan D, Larsson O, Rattenbacher B, Sternjohn JR, Vasdewani J, Karypis G, Reilly CS, Bitterman PB, Bohjanen PR. Conserved GU-rich elements mediate mRNA decay by binding to CUG-binding protein 1. Molecular Cell. 29: 263-70. PMID 18243120 DOI: 10.1016/J.Molcel.2007.11.024  0.559
2007 Wang J, Mahmud SA, Bitterman PB, Huo Y, Slungaard A. Histone deacetylase inhibitors suppress TF-kappaB-dependent agonist-driven tissue factor expression in endothelial cells and monocytes. The Journal of Biological Chemistry. 282: 28408-18. PMID 17675290 DOI: 10.1074/Jbc.M703586200  0.343
2007 Larsson O, Li S, Issaenko OA, Avdulov S, Peterson M, Smith K, Bitterman PB, Polunovsky VA. Eukaryotic translation initiation factor 4E-induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors Cancer Research. 67: 6814-6824. PMID 17638893 DOI: 10.1158/0008-5472.Can-07-0752  0.409
2007 Mullany LK, Nelsen CJ, Hanse EA, Goggin MM, Anttila CK, Peterson M, Bitterman PB, Raghavan A, Crary GS, Albrecht JH. Akt-mediated liver growth promotes induction of cyclin E through a novel translational mechanism and a p21-mediated cell cycle arrest. The Journal of Biological Chemistry. 282: 21244-52. PMID 17517888 DOI: 10.1074/Jbc.M702110200  0.348
2006 Polunovsky VA, Bitterman PB. The cap-dependent translation apparatus integrates and amplifies cancer pathways. Rna Biology. 3: 10-7. PMID 17114939 DOI: 10.4161/Rna.3.1.2718  0.344
2006 Larsson O, Perlman DM, Fan D, Reilly CS, Peterson M, Dahlgren C, Liang Z, Li S, Polunovsky VA, Wahlestedt C, Bitterman PB. Apoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure. Nucleic Acids Research. 34: 4375-86. PMID 16936314 DOI: 10.1093/Nar/Gkl558  0.579
2006 Jacobson BA, Alter MD, Kratzke MG, Frizelle SP, Zhang Y, Peterson MS, Avdulov S, Mohorn RP, Whitson BA, Bitterman PB, Polunovsky VA, Kratzke RA. Repression of cap-dependent translation attenuates the transformed phenotype in non-small cell lung cancer both in vitro and in vivo. Cancer Research. 66: 4256-62. PMID 16618749 DOI: 10.1158/0008-5472.Can-05-2879  0.432
2006 Wang J, Mahmud SA, Bitterman PB, Huo Y, Slungaard A. “TF-kB”-Dependent Suppression of Agonist-Mediated Tissue Factor Induction by Histone Deacetylase Inhibitors in Human Endothelial Cells and Monocytes. Blood. 108: 1745-1745. DOI: 10.1182/Blood.V108.11.1745.1745  0.332
2005 Kobayashi T, Liu X, Kim HJ, Kohyama T, Wen FQ, Abe S, Fang Q, Zhu YK, Spurzem JR, Bitterman P, Rennard SI. TGF-beta1 and serum both stimulate contraction but differentially affect apoptosis in 3D collagen gels. Respiratory Research. 6: 141. PMID 16324212 DOI: 10.1186/1465-9921-6-141  0.325
2004 Avdulov S, Li S, Michalek V, Burrichter D, Peterson M, Perlman DM, Manivel JC, Sonenberg N, Yee D, Bitterman PB, Polunovsky VA. Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells. Cancer Cell. 5: 553-63. PMID 15193258 DOI: 10.1016/J.Ccr.2004.05.024  0.318
2004 Li S, Perlman DM, Peterson MS, Burrichter D, Avdulov S, Polunovsky VA, Bitterman PB. Translation initiation factor 4E blocks endoplasmic reticulum-mediated apoptosis. The Journal of Biological Chemistry. 279: 21312-7. PMID 14990584 DOI: 10.1074/Jbc.M312467200  0.367
2003 Kaminski N, Belperio JA, Bitterman PB, Chen L, Chensue SW, Choi AMK, Dacic S, Dauber JH, Bois RMd, Enghild JJ, Fattman CL, Grutters JC, Haegens A, Hanford LE, Heintz N, et al. Idiopathic Pulmonary Fibrosis American Journal of Respiratory Cell and Molecular Biology. 29. PMID 12936907 DOI: 10.1165/Rcmb.2003-0159Su  0.31
2003 Li S, Takasu T, Perlman DM, Peterson MS, Burrichter D, Avdulov S, Bitterman PB, Polunovsky VA. Translation factor eIF4E rescues cells from Myc-dependent apoptosis by inhibiting cytochrome c release. The Journal of Biological Chemistry. 278: 3015-22. PMID 12441348 DOI: 10.1074/Jbc.M208821200  0.328
2002 Crystal RG, Bitterman PB, Mossman B, Schwarz MI, Sheppard D, Almasy L, Chapman HA, Friedman SL, King TE, Leinwand LA, Liotta L, Martin GR, Schwartz DA, Schultz GS, Wagner CR, et al. Future research directions in idiopathic pulmonary fibrosis: summary of a National Heart, Lung, and Blood Institute working group. American Journal of Respiratory and Critical Care Medicine. 166: 236-46. PMID 12119236 DOI: 10.1164/Rccm.2201069  0.35
2002 Li S, Sonenberg N, Gingras AC, Peterson M, Avdulov S, Polunovsky VA, Bitterman PB. Translational control of cell fate: availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency. Molecular and Cellular Biology. 22: 2853-61. PMID 11909977 DOI: 10.1128/Mcb.22.8.2853-2861.2002  0.35
2001 Rubins JB, Charboneau D, Alter MD, Bitterman PB, Kratzke RA. Inhibition of mesothelioma cell growth in vitro by doxycycline. The Journal of Laboratory and Clinical Medicine. 138: 101-6. PMID 11477376 DOI: 10.1067/Mlc.2001.116591  0.337
2001 Idell S, Mazar AP, Bitterman P, Mohla S, Harabin AL. Fibrin turnover in lung inflammation and neoplasia. American Journal of Respiratory and Critical Care Medicine. 163: 578-584. PMID 11179137 DOI: 10.1164/Ajrccm.163.2.2005135  0.387
2000 Polunovsky VA, Gingras AC, Sonenberg N, Peterson M, Tan A, Rubins JB, Manivel JC, Bitterman PB. Translational control of the antiapoptotic function of Ras. The Journal of Biological Chemistry. 275: 24776-80. PMID 10811643 DOI: 10.1074/Jbc.M001938200  0.331
2000 Panoskaltsis-Mortari A, Ingbar DH, Jung P, Haddad IY, Bitterman PB, Wangensteen OD, Farrell CL, Lacey DL, Blazar BR. KGF pretreatment decreases B7 and granzyme B expression and hastens repair in lungs of mice after allogeneic BMT. American Journal of Physiology. Lung Cellular and Molecular Physiology. 278: L988-99. PMID 10781430 DOI: 10.1152/Ajplung.2000.278.5.L988  0.335
2000 Tan A, Bitterman P, Sonenberg N, Peterson M, Polunovsky V. Inhibition of Myc-dependent apoptosis by eukaryotic translation initiation factor 4E requires cyclin D1. Oncogene. 19: 1437-47. PMID 10723135 DOI: 10.1038/Sj.Onc.1203446  0.314
1999 Tan A, Levrey H, Dahm C, Polunovsky VA, Rubins J, Bitterman PB. Lovastatin induces fibroblast apoptosis in vitro and in vivo. A possible therapy for fibroproliferative disorders. American Journal of Respiratory and Critical Care Medicine. 159: 220-7. PMID 9872842 DOI: 10.1164/Ajrccm.159.1.9802104  0.407
1998 Rubins JB, Greatens T, Kratzke RA, Tan AT, Polunovsky VA, Bitterman P. Lovastatin induces apoptosis in malignant mesothelioma cells American Journal of Respiratory and Critical Care Medicine. 157: 1616-1622. PMID 9603146 DOI: 10.1164/Ajrccm.157.5.9709020  0.346
1997 Panoskaltsis-Mortari A, Taylor PA, Yaeger TM, Wangensteen OD, Bitterman PB, Ingbar DH, Vallera DA, Blazar BR. The critical early proinflammatory events associated with idiopathic pneumonia syndrome in irradiated murine allogeneic recipients are due to donor T cell infusion and potentiated by cyclophosphamide. The Journal of Clinical Investigation. 100: 1015-27. PMID 9276718 DOI: 10.1172/Jci119612  0.413
1996 Polunovsky VA, Rosenwald IB, Tan AT, White J, Chiang L, Sonenberg N, Bitterman PB. Translational control of programmed cell death: Eukaryotic translation initiation factor 4e blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated Myc Molecular and Cellular Biology. 16: 6573-6581. PMID 8887686 DOI: 10.1128/Mcb.16.11.6573  0.367
1994 Fox JMK, Conklin K, Chiang L, Whittsett J, King MB, Mannelli WA, Harmon KR, Henke CA, Bitterman PB. Acute lung injury: A transgenic murine model of intra-alveolar fibrosis Chest. 105: 121S-122S. PMID 8131605 DOI: 10.1016/S0012-3692(15)42690-X  0.358
1994 Bitterman PB, Polunovsky VA, Ingbar DH. Repair after acute lung injury. Chest. 105: 118S-121S. PMID 8131603 DOI: 10.1378/Chest.105.3_Supplement.118S  0.364
1994 Wendt CH, Polunovsky VA, Peterson MS, Bitterman PB, Ingbar DH. Alveolar epithelial cells regulate the induction of endothelial cell apoptosis. The American Journal of Physiology. 267: C893-900. PMID 7943282 DOI: 10.1152/Ajpcell.1994.267.4.C893  0.334
1993 Polunovsky VA, Chen B, Henke C, Snover D, Wendt C, Ingbar DH, Bitterman PB. Role of mesenchymal cell death in lung remodeling after injury. The Journal of Clinical Investigation. 92: 388-97. PMID 8326006 DOI: 10.1172/Jci116578  0.416
1992 Marinelli WA, Polunovsky VA, Harmon KR, Bitterman PB. Role of platelet-derived growth factor in pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 5: 503-4. PMID 1958375 DOI: 10.1165/Ajrcmb/5.6.503  0.414
1992 Bitterman PB. Pathogenesis of fibrosis in acute lung injury. The American Journal of Medicine. 92: 39S-43S. PMID 1621743 DOI: 10.1016/0002-9343(92)90606-C  0.406
1992 Stanley MW, Henry-Stanley MJ, Gajl-Peczalska KJ, Bitterman PB. Hyperplasia of type II pneumocytes in acute lung injury. Cytologic findings of sequential bronchoalveolar lavage. American Journal of Clinical Pathology. 97: 669-77. PMID 1575213 DOI: 10.1093/Ajcp/97.5.669  0.353
1992 Hertz MI, Henke CA, Nakhleh RE, Harmon KR, Marinelli WA, Fox JM, Kubo SH, Shumway SJ, Bolman RM, Bitterman PB. Obliterative bronchiolitis after lung transplantation: a fibroproliferative disorder associated with platelet-derived growth factor. Proceedings of the National Academy of Sciences of the United States of America. 89: 10385-9. PMID 1438225 DOI: 10.1073/Pnas.89.21.10385  0.379
1992 Chen B, Polunovsky V, White J, Blazar B, Nakhleh R, Jessurun J, Peterson M, Bitterman P. Mesenchymal cells isolated after acute lung injury manifest an enhanced proliferative phenotype. The Journal of Clinical Investigation. 90: 1778-85. PMID 1430204 DOI: 10.1172/Jci116052  0.449
1991 Witkop CJ, Townsend D, Bitterman PB, Harmon K. The role of ceroid in lung and gastrointestinal disease in Hermansky-Pudlak syndrome. Advances in Experimental Medicine and Biology. 266: 283-96; discussion 2. PMID 2486155 DOI: 10.1007/978-1-4899-5339-1_20  0.419
1991 Snyder LS, Hertz MI, Peterson MS, Harmon KR, Marinelli WA, Henke CA, Greenheck JR, Chen B, Bitterman PB. Acute lung injury. Pathogenesis of intraalveolar fibrosis. The Journal of Clinical Investigation. 88: 663-73. PMID 1864975 DOI: 10.1172/Jci115351  0.376
1991 Henke C, Fiegel V, Peterson M, Wick M, Knighton D, McCarthy J, Bitterman P. Identification and partial characterization of angiogenesis bioactivity in the lower respiratory tract after acute lung injury. The Journal of Clinical Investigation. 88: 1386-95. PMID 1717512 DOI: 10.1172/Jci115445  0.412
1991 Henke C, Knighton D, Wick M, Fiegel V, Bitterman P. Mechanisms of Alveolar Fibrosis Following Acute Lung Injury Chest. 99: 40S. DOI: 10.1378/Chest.99.3_Supplement.40S  0.365
1990 Snyder LS, Hertz MI, Harmon KR, Bitterman PB. Failure of lung repair following acute lung injury. Regulation of the fibroproliferative response (Part 1). Chest. 98: 733-8. PMID 2394149 DOI: 10.1378/Chest.98.3.733  0.378
1990 Snyder LS, Hertz MI, Harmon KR, Bitterman PB. Failure of lung repair following acute lung injury. Regulation of the fibroproliferative response (Part 2). Chest. 98: 989-93. PMID 2209162 DOI: 10.1378/Chest.98.4.989  0.353
1989 Hertz MI, Englund JA, Snover D, Bitterman PB, McGlave PB. Respiratory syncytial virus-induced acute lung injury in adult patients with bone marrow transplants: a clinical approach and review of the literature. Medicine. 68: 269-81. PMID 2677595 DOI: 10.1097/00005792-198909000-00002  0.336
1989 Hencke C, Hertz M, Snyder L, Turtinen L, Harmon K, Bitterman P. Molecular Analysis of Cytomegalovirus-induced Acute Lung Injury in Organ Transplant Recipients Chest. 95: 192S. DOI: 10.1378/Chest.95.3_Supplement.192S  0.319
1988 Rennard SI, Bitterman PB, Ozaki T, Rom WN, Crystal RG. Colchicine suppresses the release of fibroblast growth factors from alveolar macrophages in vitro. The basis of a possible therapeutic approach ot the fibrotic disorders. The American Review of Respiratory Disease. 137: 181-5. PMID 3337460 DOI: 10.1164/Ajrccm/137.1.181  0.39
1988 Rom WN, Bitterman PB, Rennard SI, Cantin A, Crystal RG. Characterization of the lower respiratory tract inflammation of nonsmoking individuals with interstitial lung disease associated with chronic inhalation of inorganic dusts. The American Review of Respiratory Disease. 136: 1429-34. PMID 2825569 DOI: 10.1164/Ajrccm/136.6.1429  0.408
1986 Martinet Y, Bitterman PB, Mornex JF, Grotendorst GR, Martin GR, Crystal RG. Activated human monocytes express the c-sis proto-oncogene and release a mediator showing PDGF-like activity. Nature. 319: 158-60. PMID 3941744 DOI: 10.1038/319158A0  0.351
1986 Mornex JF, Martinet Y, Yamauchi K, Bitterman PB, Grotendorst GR, Chytil-Weir A, Martin GR, Crystal RG. Spontaneous expression of the c-sis gene and release of a platelet-derived growth factorlike molecule by human alveolar macrophages. The Journal of Clinical Investigation. 78: 61-6. PMID 3722386 DOI: 10.1172/Jci112574  0.365
1986 Bitterman PB, Rennard SI, Keogh BA, Wewers MD, Adelberg S, Crystal RG. Familial idiopathic pulmonary fibrosis. Evidence of lung inflammation in unaffected family members. The New England Journal of Medicine. 314: 1343-7. PMID 3702942 DOI: 10.1056/Nejm198605223142103  0.369
1986 Bitterman PB, Wewers MD, Rennard SI, Adelberg S, Crystal RG. Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediators. The Journal of Clinical Investigation. 77: 700-8. PMID 3081573 DOI: 10.1172/Jci112364  0.416
1985 Rossi GA, Bitterman PB, Rennard SI, Ferrans VJ, Crystal RG. Evidence for chronic inflammation as a component of the interstitial lung disease associated with progressive systemic sclerosis. The American Review of Respiratory Disease. 131: 612-7. PMID 3994157 DOI: 10.1164/Arrd.1985.131.4.612  0.415
1984 Bitterman PB, Saltzman LE, Adelberg S, Ferrans VJ, Crystal RG. Alveolar macrophage replication. One mechanism for the expansion of the mononuclear phagocyte population in the chronically inflamed lung. The Journal of Clinical Investigation. 74: 460-9. PMID 6746904 DOI: 10.1172/Jci111443  0.371
1984 Schoenberger CI, Rennard SI, Bitterman PB, Fukuda Y, Ferrans VJ, Crystal RG. Paraquat-induced pulmonary fibrosis. Role of the alveolitis in modulating the development of fibrosis. The American Review of Respiratory Disease. 129: 168-73. PMID 6703475 DOI: 10.1164/arrd.1984.129.1.168  0.311
1984 Lacronique JG, Rennard SI, Bitterman PB, Ozaki T, Crystal RG. Alveolar macrophages in idiopathic pulmonary fibrosis have glucocorticoid receptors, but glucocorticoid therapy does not suppress alveolar macrophage release of fibronectin and alveolar macrophage derived growth factor. The American Review of Respiratory Disease. 130: 450-6. PMID 6476595 DOI: 10.1164/Arrd.1984.130.3.450  0.321
1984 Crystal RG, Bitterman PB, Rennard SI, Hance AJ, Keogh BA. Interstitial lung diseases of unknown cause. Disorders characterized by chronic inflammation of the lower respiratory tract. The New England Journal of Medicine. 310: 235-44. PMID 6361563 DOI: 10.1056/Nejm198401263100406  0.315
1984 Crystal RG, Bitterman PB, Rennard SI, Hance AJ, Keogh BA. Interstitial lung diseases of unknown cause. Disorders characterized by chronic inflammation of the lower respiratory tract (first of two parts). The New England Journal of Medicine. 310: 154-66. PMID 6361560 DOI: 10.1056/Nejm198401193100304  0.36
1984 Bitterman PB, Rennard SI, Adelberg S, Crystal RG. Role of fibronectin as a growth factor for fibroblasts. The Journal of Cell Biology. 97: 1925-32. PMID 6358238 DOI: 10.1083/Jcb.97.6.1925  0.334
1984 Rennard SI, Bitterman PB, Crystal RG. Response of the lower respiratory tract to injury. Mechanisms of repair of the parenchymal cells of the alveolar wall. Chest. 84: 735-9. PMID 6357653 DOI: 10.1378/Chest.84.6.735  0.389
1983 Davis WB, Rennard SI, Bitterman PB, Crystal RG. Pulmonary oxygen toxicity. Early reversible changes in human alveolar structures induced by hyperoxia. The New England Journal of Medicine. 309: 878-83. PMID 6888481 DOI: 10.1056/Nejm198310133091502  0.339
1983 Bitterman PB, Adelberg S, Crystal RG. Mechanisms of pulmonary fibrosis. Spontaneous release of the alveolar macrophage-derived growth factor in the interstitial lung disorders. The Journal of Clinical Investigation. 72: 1801-13. PMID 6630527 DOI: 10.1172/Jci111140  0.418
1983 Pinkston P, Bitterman PB, Crystal RG. Spontaneous release of interleukin-2 by lung T lymphocytes in active pulmonary sarcoidosis. The New England Journal of Medicine. 308: 793-800. PMID 6601235 DOI: 10.1056/Nejm198304073081401  0.395
1983 Bitterman P, Rennard S, Adelberg S, Crystal RG. Role of Fibronectin in Fibrotic Lung Disease: A Growth Factor for Human Lung Fibroblasts Chest. 83. DOI: 10.1378/Chest.83.5_Supplement.96S  0.407
1983 Davis W, Rennard S, Bitterman P, Gadek J, Sun X, Wewers M, Keogh B, Crystal R. Pulmonary Oxygen Toxicity Chest. 83: 35S. DOI: 10.1378/Chest.83.5_Supplement.35S  0.329
1982 Bitterman PB, Rennard SI, Hunninghake GW, Crystal RG. Human alveolar macrophage growth factor for fibroblasts. Regulation and partial characterization. The Journal of Clinical Investigation. 70: 806-22. PMID 7119116 DOI: 10.1172/Jci110677  0.347
1982 Rennard SI, Hunninghake GW, Bitterman PB, Crystal RG. Production of fibronectin by the human alveolar macrophage: mechanism for the recruitment of fibroblasts to sites of tissue injury in interstitial lung diseases. Proceedings of the National Academy of Sciences of the United States of America. 78: 7147-51. PMID 6947279 DOI: 10.1073/Pnas.78.11.7147  0.404
1981 Bitterman P, Rennard S, Schoenberger C, Crystal R. Asbestos stimulates alveolar macrophages to release a factor causing human lung fibroblasts to replicate. Chest. 80: 38-9. PMID 7249735 DOI: 10.1378/Chest.80.1_Supplement.38S  0.371
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