Mark E. Gurney - Publications

Affiliations: 
deCode Genetics Inc 

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Butchbach ME, Singh J, Gurney ME, Burghes AH. The effect of diet on the protective action of D156844 observed in spinal muscular atrophy mice. Experimental Neurology. 256: 1-6. PMID 24681157 DOI: 10.1016/j.expneurol.2014.03.005  0.329
2010 Butchbach ME, Singh J, Thorsteinsdóttir M, Saieva L, Slominski E, Thurmond J, Andrésson T, Zhang J, Edwards JD, Simard LR, Pellizzoni L, Jarecki J, Burghes AH, Gurney ME. Effects of 2,4-diaminoquinazoline derivatives on SMN expression and phenotype in a mouse model for spinal muscular atrophy. Human Molecular Genetics. 19: 454-67. PMID 19897588 DOI: 10.1093/Hmg/Ddp510  0.37
2010 Kiselyov AS, Gurney ME. Spinal muscular atrophy: Current therapeutic strategies Topics in Medicinal Chemistry. 6: 177-192. DOI: 10.1007/7355-2010-7  0.344
2008 Singh J, Salcius M, Liu SW, Staker BL, Mishra R, Thurmond J, Michaud G, Mattoon DR, Printen J, Christensen J, Bjornsson JM, Pollok BA, Kiledjian M, Stewart L, Jarecki J, ... Gurney ME, et al. DcpS as a therapeutic target for spinal muscular atrophy. Acs Chemical Biology. 3: 711-22. PMID 18839960 DOI: 10.1021/Cb800120T  0.311
2008 Thurmond J, Butchbach ME, Palomo M, Pease B, Rao M, Bedell L, Keyvan M, Pai G, Mishra R, Haraldsson M, Andresson T, Bragason G, Thosteinsdottir M, Bjornsson JM, Coovert DD, ... ... Gurney ME, et al. Synthesis and biological evaluation of novel 2,4-diaminoquinazoline derivatives as SMN2 promoter activators for the potential treatment of spinal muscular atrophy. Journal of Medicinal Chemistry. 51: 449-69. PMID 18205293 DOI: 10.1021/jm061475p  0.367
2001 Olsen MK, Roberds SL, Ellerbrock BR, Fleck TJ, McKinley DK, Gurney ME. Disease mechanisms revealed by transcription profiling in SOD1-G93A transgenic mouse spinal cord. Annals of Neurology. 50: 730-40. PMID 11761470 DOI: 10.1002/ana.1252  0.357
2000 Shin CM, Chung YH, Kim MJ, Shin DH, Kim YS, Gurney ME, Lee KW, Cha CI. Immunohistochemical study on the distribution of Bcl-2 and Bax in the central nervous system of the transgenic mice expressing a human Cu/Zn SOD mutation. Brain Research. 887: 309-15. PMID 11134620 DOI: 10.1016/S0006-8993(00)03014-6  0.346
2000 Johnston JA, Dalton MJ, Gurney ME, Kopito RR. Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 97: 12571-6. PMID 11050163 DOI: 10.1073/pnas.220417997  0.335
2000 Gurney ME, Tomasselli AG, Heinrikson RL. Neurobiology. Stay the executioner's hand. Science (New York, N.Y.). 288: 283-4. PMID 10777410 DOI: 10.1126/Science.288.5464.283  0.304
2000 Cha CI, Chung YH, Shin CM, Shin DH, Kim YS, Gurney ME, Lee KW. Immunocytochemical study on the distribution of nitrotyrosine in the brain of the transgenic mice expressing a human Cu/Zn SOD mutation. Brain Research. 853: 156-61. PMID 10627320 DOI: 10.1016/S0006-8993(99)02302-1  0.374
1999 Cho KJ, Chung YH, Shin C, Shin DH, Kim YS, Gurney ME, Lee KW, Cha CI. Reactive astrocytes express p53 in the spinal cord of transgenic mice expressing a human Cu/Zn SOD mutation. Neuroreport. 10: 3939-43. PMID 10716237 DOI: 10.1097/00001756-199912160-00039  0.341
1999 Facchinetti F, Sasaki M, Cutting FB, Zhai P, MacDonald JE, Reif D, Beal MF, Huang PL, Dawson TM, Gurney ME, Dawson VL. Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis. Neuroscience. 90: 1483-92. PMID 10338314 DOI: 10.1016/S0306-4522(98)00492-8  0.346
1999 Shibata N, Kobayashi M, Hirano A, Asayama K, Horiuchi S, Dal Canto MC, Gurney ME. Morphological aspects of superoxide dismutase-1 mutation in amyotrophic lateral sclerosis and its transgenic mouse model Acta Histochemica Et Cytochemica. 32: 17-30. DOI: 10.1267/Ahc.32.17  0.378
1998 Andrus PK, Fleck TJ, Gurney ME, Hall ED. Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis. Journal of Neurochemistry. 71: 2041-8. PMID 9798929 DOI: 10.1046/J.1471-4159.1998.71052041.X  0.351
1998 Hall ED, Andrus PK, Oostveen JA, Fleck TJ, Gurney ME. Relationship of oxygen radical-induced lipid peroxidative damage to disease onset and progression in a transgenic model of familial ALS. Journal of Neuroscience Research. 53: 66-77. PMID 9670993 DOI: 10.1002/(SICI)1097-4547(19980701)53:1<66::AID-JNR7>3.0.CO;2-H  0.375
1998 Browne SE, Bowling AC, Baik MJ, Gurney M, Brown RH, Beal MF. Metabolic dysfunction in familial, but not sporadic, amyotrophic lateral sclerosis. Journal of Neurochemistry. 71: 281-7. PMID 9648876 DOI: 10.1046/J.1471-4159.1998.71010281.X  0.336
1998 Hall ED, Oostveen JA, Gurney ME. Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS. Glia. 23: 249-56. PMID 9633809 DOI: 10.1002/(SICI)1098-1136(199807)23:3<249::AID-GLIA7>3.0.CO;2-#  0.378
1998 Cha CI, Kim JM, Shin DH, Kim YS, Kim J, Gurney ME, Lee KW. Reactive astrocytes express nitric oxide synthase in the spinal cord of transgenic mice expressing a human Cu/Zn SOD mutation. Neuroreport. 9: 1503-6. PMID 9631456 DOI: 10.1097/00001756-199805110-00047  0.354
1998 Shibata N, Hirano A, Kobayashi M, Dal Canto MC, Gurney ME, Komori T, Umahara T, Asayama K. Presence of Cu/Zn superoxide dismutase (SOD) immunoreactivity in neuronal hyaline inclusions in spinal cords from mice carrying a transgene for Gly93Ala mutant human Cu/Zn SOD. Acta Neuropathologica. 95: 136-42. PMID 9498047 DOI: 10.1007/S004010050777  0.322
1998 Gurney ME, Fleck TJ, Himes CS, Hall ED. Riluzole preserves motor function in a transgenic model of familial amyotrophic lateral sclerosis. Neurology. 50: 62-6. PMID 9443458 DOI: 10.1212/Wnl.50.1.62  0.324
1997 Ferrante RJ, Shinobu LA, Schulz JB, Matthews RT, Thomas CE, Kowall NW, Gurney ME, Beal MF. Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation. Annals of Neurology. 42: 326-34. PMID 9307254 DOI: 10.1002/Ana.410420309  0.377
1997 Dal Canto MC, Gurney ME. A low expressor line of transgenic mice carrying a mutant human Cu,Zn superoxide dismutase (SOD1) gene develops pathological changes that most closely resemble those in human amyotrophic lateral sclerosis. Acta Neuropathologica. 93: 537-50. PMID 9194892 DOI: 10.1007/s004010050650  0.371
1997 Kostic V, Gurney ME, Deng HX, Siddique T, Epstein CJ, Przedborski S. Midbrain dopaminergic neuronal degeneration in a transgenic mouse model of familial amyotrophic lateral sclerosis. Annals of Neurology. 41: 497-504. PMID 9124807 DOI: 10.1002/Ana.410410413  0.381
1996 Gurney ME, Cutting FB, Zhai P, Doble A, Taylor CP, Andrus PK, Hall ED. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Annals of Neurology. 39: 147-57. PMID 8967745 DOI: 10.1002/Ana.410390203  0.326
1996 Tu PH, Raju P, Robinson KA, Gurney ME, Trojanowski JQ, Lee VM. Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions. Proceedings of the National Academy of Sciences of the United States of America. 93: 3155-60. PMID 8610185 DOI: 10.1073/Pnas.93.7.3155  0.383
1996 Shibata N, Hirano A, Kobayashi M, Komori T, Dol Canto MC, Gurney ME, Asayama K. PRESENCE OF SUPEROXIDE DISMUTASE-1 (SOD1) IMMUNOREACTIVITY IN HYALINE INCLUSION BODIES OF THE SPINAL CORD NEURONS OF TRANSGENIC MICE FOR MUTANT SOD1 GENE Journal of Neuropathology and Experimental Neurology. 55: 632. DOI: 10.1097/00005072-199605000-00120  0.341
1995 Chiu AY, Zhai P, Dal Canto MC, Peters TM, Kwon YW, Prattis SM, Gurney ME. Age-dependent penetrance of disease in a transgenic mouse model of familial amyotrophic lateral sclerosis. Molecular and Cellular Neurosciences. 6: 349-62. PMID 8846004 DOI: 10.1006/mcne.1995.1027  0.364
1995 Dal Canto MC, Gurney ME. Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS). Brain Research. 676: 25-40. PMID 7796176 DOI: 10.1016/0006-8993(95)00063-V  0.37
1995 Canto MCD, Gonatas NK, Chiu AY, Gurney ME. NEUROPATHOLOGICAL CHANGES IN TWO LINES OF MICE CARRYING A TRANSGENE FOR MUTANT HUMAN Cu, Zn SOD, AND IN MICE OVEREXPRESSING WILD-TYPE HUMAN SOD. A MODEL OF FAMILIAL AMYOTROPHIC LATERAL SCLEROSIS (FALS): 123 Journal of Neuropathology and Experimental Neurology. 54: 442. DOI: 10.1097/00005072-199505000-00139  0.314
1994 Gurney ME, Pu H, Chiu AY, Dal Canto MC, Polchow CY, Alexander DD, Caliendo J, Hentati A, Kwon YW, Deng HX. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science (New York, N.Y.). 264: 1772-5. PMID 8209258 DOI: 10.1126/Science.8209258  0.384
1994 Kwon YW, Gurney ME. Systemic injections of ciliary neurotrophic factor induce sprouting by adult motor neurons. Neuroreport. 5: 789-92. PMID 8018851 DOI: 10.1097/00001756-199403000-00013  0.314
1994 Gurney ME. Transgenic-mouse model of amyotrophic lateral sclerosis. The New England Journal of Medicine. 331: 1721-2. PMID 7832899 DOI: 10.1056/NEJM199412223312516  0.349
1990 Yamamoto H, Gurney ME. Human platelets contain brain-derived neurotrophic factor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 3469-78. PMID 2230938 DOI: 10.1523/Jneurosci.10-11-03469.1990  0.306
1986 Gurney ME, Heinrich SP, Lee MR, Yin HS. Molecular cloning and expression of neuroleukin, a neurotrophic factor for spinal and sensory neurons. Science (New York, N.Y.). 234: 566-74. PMID 3764429 DOI: 10.1126/Science.3764429  0.337
1982 Konishi M, Gurney ME. Sexual differentiation of brain and behaviour Trends in Neurosciences. 5: 20-23. DOI: 10.1016/0166-2236(82)90011-X  0.427
1981 Katz LC, Gurney ME. Auditory responses in the zebra finch's motor system for song. Brain Research. 221: 192-7. PMID 6168335 DOI: 10.1016/0006-8993(81)91073-8  0.567
1980 Gurney ME, Konishi M. Hormone-induced sexual differentiation of brain and behavior in zebra finches. Science (New York, N.Y.). 208: 1380-3. PMID 17775725 DOI: 10.1126/science.208.4450.1380  0.402
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