| Year |
Citation |
Score |
| 2021 |
DeCristofano L, Decker S, Schulte MK, Suryanarayanan A. Desformylflustrabromine (dFBr), a positive allosteric modulator of the αβ nicotinic receptor modulates the hypnotic response to ethanol. Alcohol (Fayetteville, N.Y.). PMID 33652092 DOI: 10.1016/j.alcohol.2021.02.005 |
0.687 |
|
| 2020 |
Mitra S, Khatri SN, Maulik M, Bult-Ito A, Schulte M. Allosterism of Nicotinic Acetylcholine Receptors: Therapeutic Potential for Neuroinflammation Underlying Brain Trauma and Degenerative Disorders. International Journal of Molecular Sciences. 21. PMID 32664647 DOI: 10.3390/Ijms21144918 |
0.351 |
|
| 2019 |
Iyer KA, Alix K, Eltit JM, Solis E, Pan X, Argade MD, Khatri S, De Felice LJ, Sweet DH, Schulte MK, Dukat M. Multi-modal antidepressant-like action of 6- and 7-chloro-2-aminodihydroquinazolines in the mouse tail suspension test. Psychopharmacology. PMID 30805668 DOI: 10.1007/S00213-019-05203-5 |
0.49 |
|
| 2018 |
Abdelkhalek AS, Alley GS, Alwassil OI, Khatri S, Mosier PD, Nyce HL, White MM, Schulte MK, Dukat M. "Methylene Bridge" to 5-HT3 Receptor Antagonists: Conformationally-Constrained Phenylguanidines". Acs Chemical Neuroscience. PMID 30375852 DOI: 10.1021/Acschemneuro.8B00431 |
0.596 |
|
| 2018 |
Dukat M, Jain AD, German N, Ferrara-Pontoriero R, Huang Y, Ma Y, Schulte MK, Glennon RA. des-Formylflustrabromine (dFBr): A Structure-Activity Study on its Ability to Potentiate the Action of Acetylcholine at α4β2 Nicotinic Acetylcholine Receptors. Acs Chemical Neuroscience. PMID 30028943 DOI: 10.1021/Acschemneuro.8B00156 |
0.403 |
|
| 2017 |
Hueffer K, Khatri S, Rideout S, Harris MB, Papke RL, Stokes C, Schulte MK. Rabies virus modifies host behaviour through a snake-toxin like region of its glycoprotein that inhibits neurotransmitter receptors in the CNS. Scientific Reports. 7: 12818. PMID 28993633 DOI: 10.1038/S41598-017-12726-4 |
0.354 |
|
| 2017 |
Bagdas D, Ergun D, Jackson A, Toma W, Schulte MK, Damaj MI. Allosteric modulation of α4β2* nicotinic acetylcholine receptors: Desformylflustrabromine potentiates antiallodynic response of nicotine in a mouse model of neuropathic pain. European Journal of Pain (London, England). PMID 28809075 DOI: 10.1002/ejp.1092 |
0.319 |
|
| 2016 |
Mitra S, Mucha M, Khatri SN, Glenon R, Schulte MK, Bult-Ito A. Attenuation of Compulsive-Like Behavior Through Positive Allosteric Modulation of α4β2 Nicotinic Acetylcholine Receptors in Non-Induced Compulsive-Like Mice. Frontiers in Behavioral Neuroscience. 10: 244. PMID 28105008 DOI: 10.3389/Fnbeh.2016.00244 |
0.393 |
|
| 2016 |
Alix K, Khatri S, Mosier PD, Casterlow S, Yan D, Nyce HL, White MM, Schulte MK, Dukat M. Super-agonist, full agonist, partial agonist and antagonist actions of arylguanidines at h5-HT3A receptors. Acs Chemical Neuroscience. PMID 27533595 DOI: 10.1021/Acschemneuro.6B00196 |
0.527 |
|
| 2015 |
Weltzin MM, Schulte MK. Desformylflustrabromine Modulates α4β2 Neuronal Nicotinic Acetylcholine Receptor High- and Low-Sensitivity Isoforms at Allosteric Clefts Containing the β2 Subunit. The Journal of Pharmacology and Experimental Therapeutics. 354: 184-94. PMID 26025967 DOI: 10.1124/Jpet.115.223933 |
0.412 |
|
| 2014 |
Weltzin MM, Huang Y, Schulte MK. Allosteric modulation of alpha4beta2 nicotinic acetylcholine receptors by HEPES. European Journal of Pharmacology. 732: 159-68. PMID 22732654 DOI: 10.1016/J.Ejphar.2012.06.001 |
0.455 |
|
| 2013 |
Dukat M, Alix K, Worsham J, Khatri S, Schulte MK. 2-Amino-6-chloro-3,4-dihydroquinazoline: A novel 5-HT3 receptor antagonist with antidepressant character. Bioorganic & Medicinal Chemistry Letters. 23: 5945-8. PMID 24035337 DOI: 10.1016/J.Bmcl.2013.08.072 |
0.579 |
|
| 2012 |
Buchapudi K, Xu X, Ataian Y, Ji HF, Schulte M. Micromechanical measurement of AChBP binding for label-free drug discovery. The Analyst. 137: 263-8. PMID 22046583 DOI: 10.1039/C1An15734E |
0.415 |
|
| 2011 |
German N, Kim JS, Jain A, Dukat M, Pandya A, Ma Y, Weltzin M, Schulte MK, Glennon RA. Deconstruction of the α4β2 nicotinic acetylcholine receptor positive allosteric modulator desformylflustrabromine Journal of Medicinal Chemistry. 54: 7259-7267. PMID 21905680 DOI: 10.1021/Jm200834X |
0.449 |
|
| 2010 |
Weltzin MM, Schulte MK. Pharmacological characterization of the allosteric modulator desformylflustrabromine and its interaction with alpha4beta2 neuronal nicotinic acetylcholine receptor orthosteric ligands. The Journal of Pharmacology and Experimental Therapeutics. 334: 917-26. PMID 20516140 DOI: 10.1124/Jpet.110.167684 |
0.476 |
|
| 2009 |
Hazai E, Joshi P, Skoviak EC, Suryanarayanan A, Schulte MK, Bikadi Z. A comprehensive study on the 5-hydroxytryptamine(3A) receptor binding of agonists serotonin and m-chlorophenylbiguanidine. Bioorganic & Medicinal Chemistry. 17: 5796-805. PMID 19640719 DOI: 10.1016/J.Bmc.2009.07.022 |
0.739 |
|
| 2007 |
Kim JS, Padnya A, Weltzin M, Edmonds BW, Schulte MK, Glennon RA. Synthesis of desformylflustrabromine and its evaluation as an α4β2 and α7 nACh receptor modulator Bioorganic and Medicinal Chemistry Letters. 17: 4855-4860. PMID 17604168 DOI: 10.1016/J.Bmcl.2007.06.047 |
0.4 |
|
| 2006 |
Joshi PR, Suryanarayanan A, Hazai E, Schulte MK, Maksay G, Bikádi Z. Interactions of granisetron with an agonist-free 5-HT3A receptor model. Biochemistry. 45: 1099-105. PMID 16430206 DOI: 10.1021/Bi051676F |
0.73 |
|
| 2005 |
Suryanarayanan A, Joshi PR, Bikádi Z, Mani M, Kulkarni TR, Gaines C, Schulte MK. The loop C region of the murine 5-HT3A receptor contributes to the differential actions of 5-hydroxytryptamine and m-chlorophenylbiguanide. Biochemistry. 44: 9140-9. PMID 15966738 DOI: 10.1021/Bi050661E |
0.752 |
|
| 2004 |
Zhang Y, Venkatachalan SP, Xu H, Xu X, Joshi P, Ji HF, Schulte M. Micromechanical measurement of membrane receptor binding for label-free drug discovery. Biosensors & Bioelectronics. 19: 1473-8. PMID 15093219 DOI: 10.1016/J.Bios.2003.12.011 |
0.543 |
|
| 2004 |
Joshi PR, Suryanarayanan A, Schulte MK. A vertical flow chamber for Xenopus oocyte electrophysiology and automated drug screening. Journal of Neuroscience Methods. 132: 69-79. PMID 14687676 DOI: 10.1016/J.Jneumeth.2003.09.002 |
0.671 |
|
| 2002 |
Venkataraman P, Venkatachalan SP, Joshi PR, Muthalagi M, Schulte MK. Identification of critical residues in loop E in the 5-HT3ASR binding site. Bmc Biochemistry. 3: 15. PMID 12079500 DOI: 10.1186/1471-2091-3-15 |
0.563 |
|
| 2002 |
Venkataraman P, Joshi P, Venkatachalan SP, Muthalagi M, Parihar HS, Kirschbaum KS, Schulte MK. Functional group interactions of a 5-HT3R antagonist. Bmc Biochemistry. 3: 16. PMID 12079499 DOI: 10.1186/1471-2091-3-16 |
0.454 |
|
| 2001 |
Parihar HS, Suryanarayanan A, Ma C, Joshi P, Venkataraman P, Schulte MK, Kirschbaum KS. 5-HT(3)R binding of lerisetron: an interdisciplinary approach to drug-Receptor interactions. Bioorganic & Medicinal Chemistry Letters. 11: 2133-6. PMID 11514154 DOI: 10.1016/S0960-894X(01)00417-6 |
0.728 |
|
| 1999 |
Yan D, Schulte MK, Bloom KE, White MM. Structural features of the ligand-binding domain of the serotonin 5HT3 receptor. The Journal of Biological Chemistry. 274: 5537-41. PMID 10026168 DOI: 10.1074/Jbc.274.9.5537 |
0.492 |
|
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