Vincent O'Connor, Ph.D - Publications

School of Biological Sciences Southampton University, Southampton, England, United Kingdom 
Neuroscience, Synapses, Prion, Alzheimer's Disease

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Pitera AP, Asuni AA, O'Connor V, Deinhardt K. Pathogenic tau does not drive activation of the unfolded protein response. The Journal of Biological Chemistry. PMID 31053641 DOI: 10.1074/jbc.RA119.008263  1
2015 Quraishe S, Wyttenbach A, Matinyarare N, Hugh Perry V, Fern R, O'Connor V. Selective and Compartmentalised Myelin Expression of HspB5. Neuroscience. PMID 26718604 DOI: 10.1016/j.neuroscience.2015.12.035  1
2015 Dallière N, Bhatla N, Luedtke Z, Ma DK, Woolman J, Walker RJ, Holden-Dye L, O'Connor V. Multiple excitatory and inhibitory neural signals converge to fine-tune Caenorhabditis elegans feeding to food availability. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26514165 DOI: 10.1096/fj.15-279257  1
2015 Dillon J, Franks CJ, Murray C, Edwards RJ, Calahorro F, Ishihara T, Katsura I, Holden-Dye L, O'Connor V. Metabotropic Glutamate Receptors: MODULATORS OF CONTEXT-DEPENDENT FEEDING BEHAVIOUR IN C. ELEGANS. The Journal of Biological Chemistry. 290: 15052-65. PMID 25869139 DOI: 10.1074/jbc.M114.606608  1
2015 Calahorro F, Holden-Dye L, O'Connor V. Analysis of splice variants for the C. elegans orthologue of human neuroligin reveals a developmentally regulated transcript. Gene Expression Patterns : Gep. 17: 69-78. PMID 25726726 DOI: 10.1016/j.gep.2015.02.002  1
2015 Davies MJ, Cooper M, Perry VH, O'Connor V. Reduced expression of the presynaptic co-chaperone cysteine string protein alpha (CSPα) does not exacerbate experimentally-induced ME7 prion disease. Neuroscience Letters. 589: 138-43. PMID 25623034 DOI: 10.1016/j.neulet.2015.01.053  1
2014 Kearn J, Ludlow E, Dillon J, O'Connor V, Holden-Dye L. Fluensulfone is a nematicide with a mode of action distinct from anticholinesterases and macrocyclic lactones. Pesticide Biochemistry and Physiology. 109: 44-57. PMID 24581383 DOI: 10.1016/j.pestbp.2014.01.004  1
2014 Asuni AA, Gray B, Bailey J, Skipp P, Perry VH, O'Connor V. Analysis of the hippocampal proteome in ME7 prion disease reveals a predominant astrocytic signature and highlights the brain-restricted production of clusterin in chronic neurodegeneration. The Journal of Biological Chemistry. 289: 4532-45. PMID 24366862 DOI: 10.1074/jbc.M113.502690  1
2014 Hu C, Kearn J, Urwin P, Lilley C, O'Connor V, Holden-Dye L, Morgan H. StyletChip: A microfluidic device for recording host invasion behaviour and feeding of plant parasitic nematodes Lab On a Chip - Miniaturisation For Chemistry and Biology. 14: 2447-2455. DOI: 10.1039/c4lc00292j  1
2013 Dillon J, Andrianakis I, Mould R, Ient B, Liu W, James C, O'Connor V, Holden-Dye L. Distinct molecular targets including SLO-1 and gap junctions are engaged across a continuum of ethanol concentrations in Caenorhabditis elegans. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4266-78. PMID 23882127 DOI: 10.1096/fj.11-189340  1
2013 Hu C, Dillon J, Kearn J, Murray C, O'Connor V, Holden-Dye L, Morgan H. NeuroChip: a microfluidic electrophysiological device for genetic and chemical biology screening of Caenorhabditis elegans adult and larvae. Plos One. 8: e64297. PMID 23717588 DOI: 10.1371/journal.pone.0064297  1
2013 Holden-Dye L, Joyner M, O'Connor V, Walker RJ. Nicotinic acetylcholine receptors: a comparison of the nAChRs of Caenorhabditis elegans and parasitic nematodes. Parasitology International. 62: 606-15. PMID 23500392 DOI: 10.1016/j.parint.2013.03.004  1
2013 Å iÅ¡ková Z, Reynolds RA, O'Connor V, Perry VH. Brain region specific pre-synaptic and post-synaptic degeneration are early components of neuropathology in prion disease. Plos One. 8: e55004. PMID 23383030 DOI: 10.1371/journal.pone.0055004  1
2013 Mulcahy B, Holden-Dye L, O'Connor V. Pharmacological assays reveal age-related changes in synaptic transmission at the Caenorhabditis elegans neuromuscular junction that are modified by reduced insulin signalling. The Journal of Experimental Biology. 216: 492-501. PMID 23038730 DOI: 10.1242/jeb.068734  1
2013 Hu C, O'Connor V, Holden-Dye L, Morgan H. Electrophysiological analysis of nematode larvae with an integrated microfluidic platform 17th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2013. 3: 1749-1751.  1
2012 Krücken J, Harder A, Jeschke P, Holden-Dye L, O'Connor V, Welz C, von Samson-Himmelstjerna G. Anthelmintic cyclcooctadepsipeptides: complex in structure and mode of action. Trends in Parasitology. 28: 385-94. PMID 22858281 DOI: 10.1016/  1
2012 Caleo M, Restani L, Vannini E, Siskova Z, Al-Malki H, Morgan R, O'Connor V, Perry VH. The role of activity in synaptic degeneration in a protein misfolding disease, prion disease. Plos One. 7: e41182. PMID 22815961 DOI: 10.1371/journal.pone.0041182  1
2012 Ient B, Edwards R, Mould R, Hannah M, Holden-Dye L, O'Connor V. HSP-4 endoplasmic reticulum (ER) stress pathway is not activated in a C. elegans model of ethanol intoxication and withdrawal. Invertebrate Neuroscience : In. 12: 93-102. PMID 22661239 DOI: 10.1007/s10158-012-0136-7  1
2012 Holden-Dye L, Crisford A, Welz C, von Samson-Himmelstjerna G, Walker RJ, O'Connor V. Worms take to the slo lane: a perspective on the mode of action of emodepside. Invertebrate Neuroscience : In. 12: 29-36. PMID 22539031 DOI: 10.1007/s10158-012-0133-x  1
2012 Hu C, O'Connor V, Holden-Dye L, Morgan H. An integrated microfluidic device for high-throughput electrophysiological analysis of C. elegans Proceedings of the 16th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2012. 1441-1443.  1
2011 Bailey JL, O'Connor V, Hannah M, Hewlett L, Biggs TE, Sundstrom LE, Findlay MW, Chad JE. In vitro CNS tissue analogues formed by self-organisation of reaggregated post-natal brain tissue. Journal of Neurochemistry. 117: 1020-32. PMID 21592119 DOI: 10.1111/j.1471-4159.2011.07276.x  1
2011 Crisford A, Murray C, O'Connor V, Edwards RJ, Kruger N, Welz C, von Samson-Himmelstjerna G, Harder A, Walker RJ, Holden-Dye L. Selective toxicity of the anthelmintic emodepside revealed by heterologous expression of human KCNMA1 in Caenorhabditis elegans. Molecular Pharmacology. 79: 1031-43. PMID 21415309 DOI: 10.1124/mol.111.071043  1
2011 Wyttenbach A, Quraishe S, Bailey J, O'Connor V. Molecular chaperones in the mammalian brain: Regional distribution, cellular compartmentalization and synaptic interactions Folding For the Synapse. 123-144. DOI: 10.1007/978-1-4419-7061-9-7  1
2011 Wyttenbach A, O'Connor V. Folding for the synapse Folding For the Synapse. 1-318. DOI: 10.1007/978-1-4419-7061-9  1
2011 Wyttenbach A, Hands S, O'Connor V. Small stress proteins in the central nervous system: From neurodegeneration to neuroprotection Small Stress Proteins and Human Diseases. 117-146.  1
2010 Luedtke S, O'Connor V, Holden-Dye L, Walker RJ. The regulation of feeding and metabolism in response to food deprivation in Caenorhabditis elegans. Invertebrate Neuroscience : In. 10: 63-76. PMID 21120572 DOI: 10.1007/s10158-010-0112-z  1
2010 Burgalossi A, Jung S, Meyer G, Jockusch WJ, Jahn O, Taschenberger H, O'Connor VM, Nishiki T, Takahashi M, Brose N, Rhee JS. SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming. Neuron. 68: 473-87. PMID 21040848 DOI: 10.1016/j.neuron.2010.09.019  1
2010 Perry VH, O'Connor V. The role of microglia in synaptic stripping and synaptic degeneration: a revised perspective. Asn Neuro. 2: e00047. PMID 20967131 DOI: 10.1042/AN20100024  1
2010 Sisková Z, Mahad DJ, Pudney C, Campbell G, Cadogan M, Asuni A, O'Connor V, Perry VH. Morphological and functional abnormalities in mitochondria associated with synaptic degeneration in prion disease. The American Journal of Pathology. 177: 1411-21. PMID 20651247 DOI: 10.2353/ajpath.2010.091037  1
2010 Mitchell P, Mould R, Dillon J, Glautier S, Andrianakis I, James C, Pugh A, Holden-Dye L, O'Connor V. A differential role for neuropeptides in acute and chronic adaptive responses to alcohol: behavioural and genetic analysis in Caenorhabditis elegans. Plos One. 5: e10422. PMID 20454655 DOI: 10.1371/journal.pone.0010422  1
2010 Asuni AA, Perry VH, O'Connor V. Change in tau phosphorylation associated with neurodegeneration in the ME7 model of prion disease. Biochemical Society Transactions. 38: 545-51. PMID 20298219 DOI: 10.1042/BST0380545  1
2010 Sisková Z, Sanyal NK, Orban A, O'Connor V, Perry VH. Reactive hypertrophy of synaptic varicosities within the hippocampus of prion-infected mice. Biochemical Society Transactions. 38: 471-5. PMID 20298205 DOI: 10.1042/BST0380471  1
2010 Brose N, O'Connor V, Skehel P. Synaptopathy: dysfunction of synaptic function? Biochemical Society Transactions. 38: 443-4. PMID 20298199 DOI: 10.1042/BST0380443  1
2010 Asuni AA, Hilton K, Siskova Z, Lunnon K, Reynolds R, Perry VH, O'Connor V. Alpha-synuclein deficiency in the C57BL/6JOlaHsd strain does not modify disease progression in the ME7-model of prion disease. Neuroscience. 165: 662-74. PMID 19879926 DOI: 10.1016/j.neuroscience.2009.10.047  1
2009 Dillon J, Andrianakis I, Bull K, Glautier S, O'Connor V, Holden-Dye L, James C. AutoEPG: software for the analysis of electrical activity in the microcircuit underpinning feeding behaviour of Caenorhabditis elegans. Plos One. 4: e8482. PMID 20041123 DOI: 10.1371/journal.pone.0008482  1
2009 Sisková Z, Page A, O'Connor V, Perry VH. Degenerating synaptic boutons in prion disease: microglia activation without synaptic stripping. The American Journal of Pathology. 175: 1610-21. PMID 19779137 DOI: 10.2353/ajpath.2009.090372  1
2009 Gray BC, Siskova Z, Perry VH, O'Connor V. Selective presynaptic degeneration in the synaptopathy associated with ME7-induced hippocampal pathology. Neurobiology of Disease. 35: 63-74. PMID 19362593 DOI: 10.1016/j.nbd.2009.04.001  1
2009 Franks CJ, Murray C, Ogden D, O'Connor V, Holden-Dye L. A comparison of electrically evoked and channel rhodopsin-evoked postsynaptic potentials in the pharyngeal system of Caenorhabditis elegans. Invertebrate Neuroscience : In. 9: 43-56. PMID 19294439 DOI: 10.1007/s10158-009-0088-8  1
2009 Jones PA, Freeman SR, Morgan R, McCabe NA, O'Connor VS, Knipe RJ. Seismic interpretation of the frontier NW Natuna basin for hydrocarbon play evaluation 71st European Association of Geoscientists and Engineers Conference and Exhibition 2009: Balancing Global Resources. Incorporating Spe Europec 2009. 5: 3013-3017.  0.56
2008 Perry VH, O'Connor V. C1q: the perfect complement for a synaptic feast? Nature Reviews. Neuroscience. 9: 807-11. PMID 18827829 DOI: 10.1038/nrn2394  1
2008 Asuni AA, Cunningham C, Vigneswaran P, Perry VH, O'Connor V. Unaltered SNARE complex formation in an in vivo model of prion disease. Brain Research. 1233: 1-7. PMID 18706894 DOI: 10.1016/j.brainres.2008.07.083  1
2008 Asuni AA, Lidwell K, O'Connor V. Biochemical evidence for the differential association of metabotropic glutamate receptors within synaptic complexes. Neuroscience Letters. 444: 27-30. PMID 18706475 DOI: 10.1016/j.neulet.2008.08.009  1
2008 Quraishe S, Asuni A, Boelens WC, O'Connor V, Wyttenbach A. Expression of the small heat shock protein family in the mouse CNS: differential anatomical and biochemical compartmentalization. Neuroscience. 153: 483-91. PMID 18384969 DOI: 10.1016/j.neuroscience.2008.01.058  1
2008 Scheschonka A, Findlow S, Schemm R, El Far O, Caldwell JH, Crump MP, Holden-Dye K, O'Connor V, Betz H, Werner JM. Structural determinants of calmodulin binding to the intracellular C-terminal domain of the metabotropic glutamate receptor 7A. The Journal of Biological Chemistry. 283: 5577-88. PMID 18089570 DOI: 10.1074/jbc.M709505200  1
2007 Holden-Dye L, O'Connor V, Hopper NA, Walker RJ, Harder A, Bull K, Guest M. SLO, SLO, quick, quick, slow: calcium-activated potassium channels as regulators of Caenorhabditis elegans behaviour and targets for anthelmintics. Invertebrate Neuroscience : In. 7: 199-208. PMID 17962986 DOI: 10.1007/s10158-007-0057-z  1
2007 Guest M, Bull K, Walker RJ, Amliwala K, O'Connor V, Harder A, Holden-Dye L, Hopper NA. The calcium-activated potassium channel, SLO-1, is required for the action of the novel cyclo-octadepsipeptide anthelmintic, emodepside, in Caenorhabditis elegans. International Journal For Parasitology. 37: 1577-88. PMID 17583712 DOI: 10.1016/j.ijpara.2007.05.006  1
2007 Mitchell PH, Bull K, Glautier S, Hopper NA, Holden-Dye L, O'Connor V. The concentration-dependent effects of ethanol on Caenorhabditis elegans behaviour. The Pharmacogenomics Journal. 7: 411-7. PMID 17325734 DOI: 10.1038/sj.tpj.6500440  1
2007 Grabauskas G, Lancaster B, O'Connor V, Wheal HV. Protein kinase signalling requirements for metabotropic action of kainate receptors in rat CA1 pyramidal neurones. The Journal of Physiology. 579: 363-73. PMID 17158174 DOI: 10.1113/jphysiol.2006.122051  1
2006 Parnas I, Rashkovan G, O'Connor V, El-Far O, Betz H, Parnas H. Role of NSF in neurotransmitter release: a peptide microinjection study at the crayfish neuromuscular junction. Journal of Neurophysiology. 96: 1053-60. PMID 16760338 DOI: 10.1152/jn.01313.2005  1
2006 Gray BC, Skipp P, O'Connor VM, Perry VH. Increased expression of glial fibrillary acidic protein fragments and mu-calpain activation within the hippocampus of prion-infected mice. Biochemical Society Transactions. 34: 51-4. PMID 16417481 DOI: 10.1042/BST0340051  1
2004 Lidwell K, Dillon J, Sihota A, O'Connor V, Pilkington B. Determining calmodulin binding to metabotropic glutamate receptors with distinct protein-interaction methods. Biochemical Society Transactions. 32: 868-70. PMID 15494036 DOI: 10.1042/BST0320868  0.64
2004 Willson J, Amliwala K, Davis A, Cook A, Cuttle MF, Kriek N, Hopper NA, O'Connor V, Harder A, Walker RJ, Holden-Dye L. Latrotoxin receptor signaling engages the UNC-13-dependent vesicle-priming pathway in C. elegans. Current Biology : Cb. 14: 1374-9. PMID 15296755 DOI: 10.1016/j.cub.2004.07.056  1
2004 O'Connor V, Houtman SH, De Zeeuw CI, Bliss TV, French PJ. Eml5, a novel WD40 domain protein expressed in rat brain. Gene. 336: 127-37. PMID 15225882 DOI: 10.1016/j.gene.2004.04.012  1
2004 O'Connor V, Genin A, Davis S, Karishma KK, Doyère V, De Zeeuw CI, Sanger G, Hunt SP, Richter-Levin G, Mallet J, Laroche S, Bliss TV, French PJ. Differential amplification of intron-containing transcripts reveals long term potentiation-associated up-regulation of specific Pde10A phosphodiesterase splice variants. The Journal of Biological Chemistry. 279: 15841-9. PMID 14752115 DOI: 10.1074/jbc.M312500200  1
2003 Génin A, French P, Doyère V, Davis S, Errington ML, Maroun M, Stean T, Truchet B, Webber M, Wills T, Richter-Levin G, Sanger G, Hunt SP, Mallet J, Laroche S, et al. LTP but not seizure is associated with up-regulation of AKAP-150. The European Journal of Neuroscience. 17: 331-40. PMID 12542670 DOI: 10.1046/j.1460-9568.2003.02462.x  1
2001 French PJ, O'Connor V, Voss K, Stean T, Hunt SP, Bliss TV. Seizure-induced gene expression in area CA1 of the mouse hippocampus. The European Journal of Neuroscience. 14: 2037-41. PMID 11860499 DOI: 10.1046/j.0953-816X.2001.01818.x  1
2001 French PJ, Bliss TV, O'Connor V. Ntab, a novel non-coding RNA abundantly expressed in rat brain. Neuroscience. 108: 207-15. PMID 11734355 DOI: 10.1016/S0306-4522(01)00408-0  1
2001 El Far O, Bofill-Cardona E, Airas JM, O'Connor V, Boehm S, Freissmuth M, Nanoff C, Betz H. Mapping of calmodulin and Gbetagamma binding domains within the C-terminal region of the metabotropic glutamate receptor 7A. The Journal of Biological Chemistry. 276: 30662-9. PMID 11395497 DOI: 10.1074/jbc.M102573200  1
2001 French PJ, O'Connor V, Jones MW, Davis S, Errington ML, Voss K, Truchet B, Wotjak C, Stean T, Doyère V, Maroun M, Laroche S, Bliss TV. Subfield-specific immediate early gene expression associated with hippocampal long-term potentiation in vivo. The European Journal of Neuroscience. 13: 968-76. PMID 11264669 DOI: 10.1046/j.0953-816X.2001.01467.x  1
1999 O'Connor V, El Far O, Bofill-Cardona E, Nanoff C, Freissmuth M, Karschin A, Airas JM, Betz H, Boehm S. Calmodulin dependence of presynaptic metabotropic glutamate receptor signaling. Science (New York, N.Y.). 286: 1180-4. PMID 10550060 DOI: 10.1126/science.286.5442.1180  1
1998 el Far O, O'Connor V, Dresbach T, Pellegrini L, DeBello W, Schweizer F, Augustine G, Heuss C, Schäfer T, Charlton MP, Betz H. Protein interactions implicated in neurotransmitter release. Journal of Physiology, Paris. 92: 129-33. PMID 9782456 DOI: 10.1016/S0928-4257(98)80150-2  1
1998 Dresbach T, Burns ME, O'Connor V, DeBello WM, Betz H, Augustine GJ. A neuronal Sec1 homolog regulates neurotransmitter release at the squid giant synapse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2923-32. PMID 9526009  1
1998 Schweizer FE, Dresbach T, DeBello WM, O'Connor V, Augustine GJ, Betz H. Regulation of neurotransmitter release kinetics by NSF. Science (New York, N.Y.). 279: 1203-6. PMID 9469810 DOI: 10.1126/science.279.5354.1203  1
1997 O'Connor V, Heuss C, De Bello WM, Dresbach T, Charlton MP, Hunt JH, Pellegrini LL, Hodel A, Burger MM, Betz H, Augustine GJ, Schäfer T. Disruption of syntaxin-mediated protein interactions blocks neurotransmitter secretion. Proceedings of the National Academy of Sciences of the United States of America. 94: 12186-91. PMID 9342384 DOI: 10.1073/pnas.94.22.12186  1
1997 Capogna M, McKinney RA, O'Connor V, Gähwiler BH, Thompson SM. Ca2+ or Sr2+ partially rescues synaptic transmission in hippocampal cultures treated with botulinum toxin A and C, but not tetanus toxin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7190-202. PMID 9295365  1
1996 O'Connor V, Phelan PP, Fry JP. Interactions of glycine and strychnine with their receptor recognition sites in mouse spinal cord. Neurochemistry International. 29: 423-34. PMID 8939452 DOI: 10.1016/0197-0186(95)00160-3  1
1996 O'Connor V, Pellegrini L, Dresbach T, Bommert K, el Far O, Betz H, DeBello W, Hunt JM, Schweizer F, Augustine G, Charlton MP. Protein-protein interactions in synaptic vesicle exocytosis. Biochemical Society Transactions. 24: 666-70. PMID 8878823  1
1995 Burns ME, Beushausen SA, Chin GJ, Tang D, DeBello WM, Dresbach T, O'Connor V, Schweizer FE, Wang SS, Whiteheart SW. Proteins involved in synaptic vesicle docking and fusion. Cold Spring Harbor Symposia On Quantitative Biology. 60: 337-48. PMID 8824407 DOI: 10.1101/SQB.1995.060.01.038  1
1995 DeBello WM, O'Connor V, Dresbach T, Whiteheart SW, Wang SS, Schweizer FE, Betz H, Rothman JE, Augustine GJ. SNAP-mediated protein-protein interactions essential for neurotransmitter release. Nature. 373: 626-30. PMID 7854421 DOI: 10.1038/373626a0  1
1994 O'Connor V, Duggan M, Siebert A, Bommert K, DeBello W, Augustine G, Betz H. Molecular approaches to neurotransmitter release. Annals of the New York Academy of Sciences. 733: 290-7. PMID 7978878 DOI: 10.1111/j.1749-6632.1994.tb17278.x  1
1994 O'Connor V, Augustine GJ, Betz H. Synaptic vesicle exocytosis: molecules and models. Cell. 76: 785-7. PMID 7907278 DOI: 10.1016/0092-8674(94)90352-2  1
1990 O'Connor VM, de Alwis MA, Khan JA, Fry JP. Chemical modification of spinal cord membranes reveals [3H]strychnine binding sites that are not located on the 48 kDa subunit of the synaptic glycine receptor. Biochemical Society Transactions. 18: 893. PMID 1964652  1
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