☰

Basil P. Hubbard, Ph.D. - Publications

Affiliations: 
2011 Harvard University, Cambridge, MA, United States 
Area:
Biochemistry, Molecular Biology, Genetics
Tree Info Similar researchers PubMed Report error

23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Salla M, Pandya V, Bhullar KS, Kerek E, Wong YF, Losch R, Ou J, Aldawsari FS, Velazquez-Martinez C, Thiesen A, Dyck JRB, Hubbard BP, Baksh S. Resveratrol and Resveratrol-Aspirin Hybrid Compounds as Potent Intestinal Anti-Inflammatory and Anti-Tumor Drugs. Molecules (Basel, Switzerland). 25. PMID 32847114 DOI: 10.3390/Molecules25173849  0.411
2018 Salla M, Aguayo-Ortiz R, Gaddafi Ibrahim D, Zare A, Said A, Moore J, Pandya V, Manaloor R, Fong S, Blankstein AR, Gibson S, Garcia LR, Meier P, Bhullar KS, Hubbard BP, et al. Identification and Characterization of Novel Receptor Interacting Serine/threonine-Protein Kinase 2 (RIPK2) Inhibitors Using Structural Similarity Analysis. The Journal of Pharmacology and Experimental Therapeutics. PMID 29555876 DOI: 10.1124/Jpet.117.247163  0.381
2017 Li J, Bonkowski MS, Moniot S, Zhang D, Hubbard BP, Ling AJ, Rajman LA, Qin B, Lou Z, Gorbunova V, Aravind L, Steegborn C, Sinclair DA. A conserved NAD(+) binding pocket that regulates protein-protein interactions during aging. Science (New York, N.Y.). 355: 1312-1317. PMID 28336669 DOI: 10.1126/Science.Aad8242  0.515
2016 Van Meter M, Simon M, Tombline G, May A, Morello TD, Hubbard BP, Bredbenner K, Park R, Sinclair DA, Bohr VA, Gorbunova V, Seluanov A. JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks. Cell Reports. PMID 27568560 DOI: 10.1016/J.Celrep.2016.08.006  0.474
2016 Dai H, Ellis JL, Sinclair DA, Hubbard BP. Synthesis and Assay of SIRT1-Activating Compounds. Methods in Enzymology. 574: 213-44. PMID 27423864 DOI: 10.1016/Bs.Mie.2016.01.012  0.589
2015 Hubbard BP, Badran AH, Zuris JA, Guilinger JP, Davis KM, Chen L, Tsai SQ, Sander JD, Joung JK, Liu DR. Continuous directed evolution of DNA-binding proteins to improve TALEN specificity. Nature Methods. 12: 939-42. PMID 26258293 DOI: 10.1038/Nmeth.3515  0.329
2015 Bhullar KS, Hubbard BP. Lifespan and healthspan extension by resveratrol. Biochimica Et Biophysica Acta. 1852: 1209-18. PMID 25640851 DOI: 10.1016/J.Bbadis.2015.01.012  0.349
2014 Hubbard BP, Sinclair DA. Small molecule SIRT1 activators for the treatment of aging and age-related diseases. Trends in Pharmacological Sciences. 35: 146-54. PMID 24439680 DOI: 10.1016/J.Tips.2013.12.004  0.552
2013 Gomes AP, Price NL, Ling AJ, Moslehi JJ, Montgomery MK, Rajman L, White JP, Teodoro JS, Wrann CD, Hubbard BP, Mercken EM, Palmeira CM, de Cabo R, Rolo AP, Turner N, et al. Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell. 155: 1624-38. PMID 24360282 DOI: 10.1016/J.Cell.2013.11.037  0.509
2013 Hubbard BP, Sinclair DA. Measurement of sirtuin enzyme activity using a substrate-agnostic fluorometric nicotinamide assay. Methods in Molecular Biology (Clifton, N.J.). 1077: 167-77. PMID 24014406 DOI: 10.1007/978-1-62703-637-5_11  0.517
2013 Hubbard BP, Loh C, Gomes AP, Li J, Lu Q, Doyle TL, Disch JS, Armour SM, Ellis JL, Vlasuk GP, Sinclair DA. Carboxamide SIRT1 inhibitors block DBC1 binding via an acetylation-independent mechanism. Cell Cycle (Georgetown, Tex.). 12: 2233-40. PMID 23892437 DOI: 10.4161/Cc.25268  0.703
2013 Biason-Lauber A, Böni-Schnetzler M, Hubbard BP, Bouzakri K, Brunner A, Cavelti-Weder C, Keller C, Meyer-Böni M, Meier DT, Brorsson C, Timper K, Leibowitz G, Patrignani A, Bruggmann R, Boily G, et al. Identification of a SIRT1 mutation in a family with type 1 diabetes. Cell Metabolism. 17: 448-55. PMID 23473037 DOI: 10.1016/J.Cmet.2013.02.001  0.441
2013 Hubbard BP, Gomes AP, Dai H, Li J, Case AW, Considine T, Riera TV, Lee JE, E SY, Lamming DW, Pentelute BL, Schuman ER, Stevens LA, Ling AJ, Armour SM, et al. Evidence for a common mechanism of SIRT1 regulation by allosteric activators. Science (New York, N.Y.). 339: 1216-9. PMID 23471411 DOI: 10.1126/Science.1231097  0.676
2013 Han J, Hubbard BP, Lee J, Montagna C, Lee HW, Sinclair DA, Suh Y. Analysis of 41 cancer cell lines reveals excessive allelic loss and novel mutations in the SIRT1 gene. Cell Cycle (Georgetown, Tex.). 12: 263-70. PMID 23255128 DOI: 10.4161/Cc.23056  0.535
2013 Minor RK, Baur JA, Gomes AP, Ward TM, Csiszar A, Mercken EM, Abdelmohsen K, Shin Y, Canto C, Scheibye-Knudsen M, Krawczyk M, Irusta PM, Martín-Montalvo A, Hubbard BP, Zhang Y, et al. Erratum: CORRIGENDUM: SRT1720 improves survival and healthspan of obese mice Scientific Reports. 3. DOI: 10.1038/Srep01131  0.444
2012 Rascón B, Hubbard BP, Sinclair DA, Amdam GV. The lifespan extension effects of resveratrol are conserved in the honey bee and may be driven by a mechanism related to caloric restriction. Aging. 4: 499-508. PMID 22868943  0.414
2012 Price NL, Gomes AP, Ling AJ, Duarte FV, Martin-Montalvo A, North BJ, Agarwal B, Ye L, Ramadori G, Teodoro JS, Hubbard BP, Varela AT, Davis JG, Varamini B, Hafner A, et al. SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. Cell Metabolism. 15: 675-90. PMID 22560220 DOI: 10.1016/J.Cmet.2012.04.003  0.529
2012 Gomes AP, Duarte FV, Nunes P, Hubbard BP, Teodoro JS, Varela AT, Jones JG, Sinclair DA, Palmeira CM, Rolo AP. Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis. Biochimica Et Biophysica Acta. 1822: 185-95. PMID 22027215 DOI: 10.1016/J.Bbadis.2011.10.008  0.509
2012 Liu H, Hubbard B, Sinclair D, Ma J, Sturges M, Armstrong L. Abstract 216: Novel assays for Sirtuin and PARP families utilizing unmodified substrates Cancer Research. 72: 216-216. DOI: 10.1158/1538-7445.Am2012-216  0.535
2011 Minor RK, Baur JA, Gomes AP, Ward TM, Csiszar A, Mercken EM, Abdelmohsen K, Shin YK, Canto C, Scheibye-Knudsen M, Krawczyk M, Irusta PM, Martín-Montalvo A, Hubbard BP, Zhang Y, et al. SRT1720 improves survival and healthspan of obese mice. Scientific Reports. 1: 70. PMID 22355589 DOI: 10.1038/Srep00070  0.563
2011 Bernier M, Paul RK, Martin-Montalvo A, Scheibye-Knudsen M, Song S, He HJ, Armour SM, Hubbard BP, Bohr VA, Wang L, Zong Y, Sinclair DA, de Cabo R. Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein. The Journal of Biological Chemistry. 286: 19270-9. PMID 21467030 DOI: 10.1074/Jbc.M110.200311  0.7
2010 Dai H, Kustigian L, Carney D, Case A, Considine T, Hubbard BP, Perni RB, Riera TV, Szczepankiewicz B, Vlasuk GP, Stein RL. SIRT1 activation by small molecules: kinetic and biophysical evidence for direct interaction of enzyme and activator. The Journal of Biological Chemistry. 285: 32695-703. PMID 20702418 DOI: 10.1074/Jbc.M110.133892  0.428
2010 Yang Y, Hubbard BP, Sinclair DA, Tong Q. Characterization of murine SIRT3 transcript variants and corresponding protein products. Journal of Cellular Biochemistry. 111: 1051-8. PMID 20677216 DOI: 10.1002/Jcb.22795  0.47
Show low-probability matches.