Year |
Citation |
Score |
2022 |
Idol RA, Bhattacharya S, Huang G, Song Z, Huttenlocher A, Keller NP, Dinauer MC. Neutrophil and Macrophage NADPH Oxidase 2 Differentially Control Responses to Inflammation and to Aspergillus fumigatus in Mice. Journal of Immunology (Baltimore, Md. : 1950). 209: 1960-1972. PMID 36426951 DOI: 10.4049/jimmunol.2200543 |
0.314 |
|
2020 |
Song Z, Huang G, Chiquetto Paracatu L, Grimes DJ, Gu J, Luke CJ, Clemens RA, Dinauer MC. NADPH oxidase controls pulmonary neutrophil infiltration in the response to fungal cell walls by limiting LTB4. Blood. PMID 31951647 DOI: 10.1182/Blood.2019003525 |
0.427 |
|
2020 |
Dinauer MC. Neutrophil Defects and Diagnosis Disorders of Neutrophil Function: An Overview. Methods in Molecular Biology (Clifton, N.J.). 2087: 11-29. PMID 31728980 DOI: 10.1007/978-1-0716-0154-9_2 |
0.302 |
|
2019 |
Dinauer MC. Insights into the NOX NADPH Oxidases Using Heterologous Whole Cell Assays. Methods in Molecular Biology (Clifton, N.J.). 1982: 139-151. PMID 31172471 DOI: 10.1007/978-1-4939-9424-3_9 |
0.349 |
|
2019 |
Jang JS, Kang IS, Cha YN, Lee ZH, Dinauer MC, Kim YJ, Kim C. Vav1 inhibits RANKL-induced osteoclast differentiation and bone resorption. Bmb Reports. PMID 31072447 DOI: 10.5483/Bmbrep.2019.52.11.013 |
0.322 |
|
2019 |
Dinauer MC. Inflammatory consequences of inherited disorders affecting neutrophil function. Blood. PMID 30898864 DOI: 10.1182/Blood-2018-11-844563 |
0.334 |
|
2019 |
Dinauer MC, Song Z, Huang G, Luke CJ, Clemens RA. NADPH Oxidase Controls Neutrophil Infiltration in the Lung in Early Response to Fungal Cell Walls Via LTB4 Blood. 134: 214-214. DOI: 10.1182/Blood-2019-130664 |
0.398 |
|
2018 |
van de Geer A, Nieto-Patlán A, Kuhns DB, Tool AT, Arias AA, Bouaziz M, de Boer M, Franco JL, Gazendam RP, van Hamme JL, van Houdt M, van Leeuwen K, Verkuijlen PJ, van den Berg TK, Alzate JF, ... ... Dinauer MC, et al. Inherited p40phox deficiency differs from classic chronic granulomatous disease. The Journal of Clinical Investigation. PMID 29969437 DOI: 10.1172/Jci97116 |
0.378 |
|
2018 |
Bagaitkar J, Huang J, Zeng MY, Pech NK, Monlish DA, Perez-Zapata LJ, Miralda I, Schuettpelz LG, Dinauer MC. NADPH oxidase activation regulates apoptotic neutrophil clearance by murine macrophages. Blood. PMID 29618478 DOI: 10.1182/Blood-2017-09-809004 |
0.752 |
|
2018 |
Yokoyama CC, Baldridge MT, Leung DW, Zhao G, Desai C, Liu TC, Diaz-Ochoa VE, Huynh JP, Kimmey JM, Sennott EL, Hole CR, Idol RA, Park S, Storek KM, Wang C, ... ... Dinauer MC, et al. LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens. The Journal of Biological Chemistry. PMID 29496999 DOI: 10.1074/Jbc.Ra117.001246 |
0.362 |
|
2018 |
Dinauer MC. NOX2 NADPH oxidase controls responses to infection and sterile inflammation Free Radical Biology and Medicine. 120: S22. DOI: 10.1016/J.Freeradbiomed.2018.04.092 |
0.385 |
|
2017 |
Jacob CO, Yu N, Yoo DG, Perez-Zapata LJ, Barbu EA, Kaplan MJ, Purmalek M, Pingel JT, Idol RA, Dinauer MC. Haploinsufficiency of NADPH oxidase subunit NCF2 is sufficient to accelerate full-blown lupus in NZM.2328 mice. Arthritis & Rheumatology (Hoboken, N.J.). PMID 28471497 DOI: 10.1002/Art.40141 |
0.355 |
|
2016 |
Dinauer MC. Primary immune deficiencies with defects in neutrophil function. Hematology. American Society of Hematology. Education Program. 2016: 43-50. PMID 27913461 DOI: 10.1182/Asheducation-2016.1.43 |
0.364 |
|
2016 |
Bagaitkar J, Barbu EA, Perez-Zapata LJ, Austin A, Huang G, Pallat S, Dinauer MC. PI(3)P-p40phox binding regulates NADPH oxidase activation in mouse macrophages and magnitude of inflammatory responses in vivo. Journal of Leukocyte Biology. PMID 27543673 DOI: 10.1189/Jlb.3Ab0316-139R |
0.418 |
|
2016 |
Lu Q, Yokoyama CC, Williams JW, Baldridge MT, Jin X, DesRochers B, Bricker T, Wilen CB, Bagaitkar J, Loginicheva E, Sergushichev A, Kreamalmeyer D, Keller BC, Zhao Y, Kambal A, ... ... Dinauer MC, et al. Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis. Cell Host & Microbe. 19: 102-113. PMID 26764600 DOI: 10.1016/J.Chom.2015.12.011 |
0.312 |
|
2015 |
Bagaitkar J, Pech NK, Ivanov S, Austin A, Zeng MY, Pallat S, Huang G, Randolph GJ, Dinauer MC. NADPH oxidase controls neutrophilic response to sterile inflammation in mice by regulating IL-1α/G-CSF axis. Blood. PMID 26443623 DOI: 10.1182/Blood-2015-05-644773 |
0.721 |
|
2015 |
McLetchie S, Volpp BD, Dinauer MC, Blum JS. Hyper-responsive Toll-like receptor 7 and 9 activation in NADPH oxidase-deficient B lymphoblasts. Immunology. PMID 26340429 DOI: 10.1111/Imm.12530 |
0.453 |
|
2015 |
Gomez JC, Yamada M, Martin JR, Dang H, Brickey WJ, Bergmeier W, Dinauer MC, Doerschuk CM. Mechanisms of interferon-γ production by neutrophils and its function during Streptococcus pneumoniae pneumonia. American Journal of Respiratory Cell and Molecular Biology. 52: 349-64. PMID 25100610 DOI: 10.1165/Rcmb.2013-0316Oc |
0.344 |
|
2014 |
Roos D, van Buul JD, Tool AT, Matute JD, Marchal CM, Hayee B, Köker MY, de Boer M, van Leeuwen K, Segal AW, Pick E, Dinauer MC. Two CGD Families with a Hypomorphic Mutation in the Activation Domain of p67(phox). Journal of Clinical & Cellular Immunology. 5. PMID 25937994 DOI: 10.4172/2155-9899.1000231 |
0.346 |
|
2014 |
Bagaitkar J, Stoyan I, Pech N, Huang G, Dinauer MC. NADPH Oxidase Limits Sterile Inflammation By Modulating IL-1/G-CSF-Driven Neutrophilic Inflammation Blood. 124: 458-458. DOI: 10.1182/Blood.V124.21.458.458 |
0.356 |
|
2013 |
Patel KK, Miyoshi H, Beatty WL, Head RD, Malvin NP, Cadwell K, Guan JL, Saitoh T, Akira S, Seglen PO, Dinauer MC, Virgin HW, Stappenbeck TS. Autophagy proteins control goblet cell function by potentiating reactive oxygen species production. The Embo Journal. 32: 3130-44. PMID 24185898 DOI: 10.1038/Emboj.2013.233 |
0.354 |
|
2013 |
Nunes P, Demaurex N, Dinauer MC. Regulation of the NADPH oxidase and associated ion fluxes during phagocytosis. Traffic (Copenhagen, Denmark). 14: 1118-31. PMID 23980663 DOI: 10.1111/Tra.12115 |
0.373 |
|
2013 |
Stein S, Scholz S, Schwäble J, Sadat MA, Modlich U, Schultze-Strasser S, Diaz M, Chen-Wichmann L, Müller-Kuller U, Brendel C, Fronza R, Kaufmann KB, Naundorf S, Pech NK, Travers JB, ... ... Dinauer MC, et al. From bench to bedside: preclinical evaluation of a self-inactivating gammaretroviral vector for the gene therapy of X-linked chronic granulomatous disease. Human Gene Therapy. Clinical Development. 24: 86-98. PMID 23845071 DOI: 10.1089/Humc.2013.019 |
0.337 |
|
2013 |
Zeng MY, Pham D, Bagaitkar J, Liu J, Otero K, Shan M, Wynn TA, Brombacher F, Brutkiewicz RR, Kaplan MH, Dinauer MC. An efferocytosis-induced, IL-4-dependent macrophage-iNKT cell circuit suppresses sterile inflammation and is defective in murine CGD. Blood. 121: 3473-83. PMID 23426944 DOI: 10.1182/Blood-2012-10-461913 |
0.722 |
|
2012 |
Bagaitkar J, Matute JD, Austin A, Arias AA, Dinauer MC. Activation of neutrophil respiratory burst by fungal particles requires phosphatidylinositol 3-phosphate binding to p40(phox) in humans but not in mice. Blood. 120: 3385-7. PMID 23086626 DOI: 10.1182/Blood-2012-07-445619 |
0.387 |
|
2012 |
Crotzer VL, Matute JD, Arias AA, Zhao H, Quilliam LA, Dinauer MC, Blum JS. Cutting edge: NADPH oxidase modulates MHC class II antigen presentation by B cells. Journal of Immunology (Baltimore, Md. : 1950). 189: 3800-4. PMID 22984083 DOI: 10.4049/Jimmunol.1103080 |
0.406 |
|
2012 |
Casbon AJ, Long ME, Dunn KW, Allen LA, Dinauer MC. Effects of IFN-γ on intracellular trafficking and activity of macrophage NADPH oxidase flavocytochrome b558. Journal of Leukocyte Biology. 92: 869-82. PMID 22822009 DOI: 10.1189/Jlb.0512244 |
0.779 |
|
2012 |
Jacob CO, Eisenstein M, Dinauer MC, Ming W, Liu Q, John S, Quismorio FP, Reiff A, Myones BL, Kaufman KM, McCurdy D, Harley JB, Silverman E, Kimberly RP, Vyse TJ, et al. Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase. Proceedings of the National Academy of Sciences of the United States of America. 109: E59-67. PMID 22203994 DOI: 10.1073/Pnas.1113251108 |
0.309 |
|
2011 |
Mahankali M, Peng HJ, Henkels KM, Dinauer MC, Gomez-Cambronero J. Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2. Proceedings of the National Academy of Sciences of the United States of America. 108: 19617-22. PMID 22106281 DOI: 10.1073/Pnas.1114692108 |
0.35 |
|
2011 |
Peng HJ, Henkels KM, Mahankali M, Marchal C, Bubulya P, Dinauer MC, Gomez-Cambronero J. The dual effect of Rac2 on phospholipase D2 regulation that explains both the onset and termination of chemotaxis. Molecular and Cellular Biology. 31: 2227-40. PMID 21444720 DOI: 10.1128/Mcb.01348-10 |
0.349 |
|
2011 |
Peng HJ, Henkels KM, Mahankali M, Dinauer MC, Gomez-Cambronero J. Evidence for two CRIB domains in phospholipase D2 (PLD2) that the enzyme uses to specifically bind to the small GTPase Rac2. The Journal of Biological Chemistry. 286: 16308-20. PMID 21378159 DOI: 10.1074/Jbc.M110.206672 |
0.363 |
|
2011 |
Bustamante J, Arias AA, Vogt G, Picard C, Galicia LB, Prando C, Grant AV, Marchal CC, Hubeau M, Chapgier A, de Beaucoudrey L, Puel A, Feinberg J, Valinetz E, Jannière L, ... ... Dinauer MC, et al. Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease. Nature Immunology. 12: 213-21. PMID 21278736 DOI: 10.1038/Ni.1992 |
0.364 |
|
2011 |
Yamada M, Gomez JC, Chugh PE, Lowell CA, Dinauer MC, Dittmer DP, Doerschuk CM. Interferon-γ production by neutrophils during bacterial pneumonia in mice. American Journal of Respiratory and Critical Care Medicine. 183: 1391-401. PMID 21169470 DOI: 10.1164/Rccm.201004-0592Oc |
0.343 |
|
2010 |
Li XJ, Marchal CC, Stull ND, Stahelin RV, Dinauer MC. p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation. The Journal of Biological Chemistry. 285: 35169-79. PMID 20817944 DOI: 10.1074/Jbc.M110.164475 |
0.417 |
|
2010 |
Xue X, Pech NK, Shelley WC, Srour EF, Yoder MC, Dinauer MC. Antibody targeting KIT as pretransplantation conditioning in immunocompetent mice. Blood. 116: 5419-22. PMID 20813896 DOI: 10.1182/Blood-2010-07-295949 |
0.306 |
|
2010 |
Fernandez-Boyanapalli R, McPhillips KA, Frasch SC, Janssen WJ, Dinauer MC, Riches DW, Henson PM, Byrne A, Bratton DL. Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN-γ in a nitric oxide-dependent manner. Journal of Immunology (Baltimore, Md. : 1950). 185: 4030-41. PMID 20805415 DOI: 10.4049/Jimmunol.1001778 |
0.394 |
|
2010 |
Lasater EA, Li F, Bessler WK, Estes ML, Vemula S, Hingtgen CM, Dinauer MC, Kapur R, Conway SJ, Ingram DA. Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans. The Journal of Clinical Investigation. 120: 859-70. PMID 20160346 DOI: 10.1172/Jci41443 |
0.321 |
|
2010 |
Nie B, Cheng N, Dinauer MC, Ye RD. Characterization of P-Rex1 for its role in fMet-Leu-Phe-induced superoxide production in reconstituted COS(phox) cells. Cellular Signalling. 22: 770-82. PMID 20074642 DOI: 10.1016/J.Cellsig.2010.01.001 |
0.405 |
|
2010 |
Lewis EM, Sergeant S, Ledford B, Stull N, Dinauer MC, McPhail LC. Phosphorylation of p22phox on threonine 147 enhances NADPH oxidase activity by promoting p47phox binding. The Journal of Biological Chemistry. 285: 2959-67. PMID 19948736 DOI: 10.1074/Jbc.M109.030643 |
0.389 |
|
2009 |
Matute JD, Arias AA, Wright NA, Wrobel I, Waterhouse CC, Li XJ, Marchal CC, Stull ND, Lewis DB, Steele M, Kellner JD, Yu W, Meroueh SO, Nauseef WM, Dinauer MC. A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity. Blood. 114: 3309-15. PMID 19692703 DOI: 10.1182/Blood-2009-07-231498 |
0.382 |
|
2009 |
Sadat MA, Dirscherl S, Sastry L, Dantzer J, Pech N, Griffin S, Hawkins T, Zhao Y, Barese CN, Cross S, Orazi A, An C, Goebel WS, Yoder MC, Li X, ... ... Dinauer MC, et al. Retroviral vector integration in post-transplant hematopoiesis in mice conditioned with either submyeloablative or ablative irradiation. Gene Therapy. 16: 1452-64. PMID 19657370 DOI: 10.1038/Gt.2009.96 |
0.322 |
|
2009 |
Huang J, Canadien V, Lam GY, Steinberg BE, Dinauer MC, Magalhaes MA, Glogauer M, Grinstein S, Brumell JH. Activation of antibacterial autophagy by NADPH oxidases. Proceedings of the National Academy of Sciences of the United States of America. 106: 6226-31. PMID 19339495 DOI: 10.1073/Pnas.0811045106 |
0.35 |
|
2009 |
Casbon AJ, Allen LA, Dunn KW, Dinauer MC. Macrophage NADPH oxidase flavocytochrome B localizes to the plasma membrane and Rab11-positive recycling endosomes. Journal of Immunology (Baltimore, Md. : 1950). 182: 2325-39. PMID 19201887 DOI: 10.4049/Jimmunol.0803476 |
0.767 |
|
2009 |
Distasi MR, Case J, Ziegler MA, Dinauer MC, Yoder MC, Haneline LS, Dalsing MC, Miller SJ, Labarrere CA, Murphy MP, Ingram DA, Unthank JL. Suppressed hindlimb perfusion in Rac2-/- and Nox2-/- mice does not result from impaired collateral growth. American Journal of Physiology. Heart and Circulatory Physiology. 296: H877-86. PMID 19151256 DOI: 10.1152/Ajpheart.00772.2008 |
0.322 |
|
2009 |
Li XJ, Tian W, Stull ND, Grinstein S, Atkinson S, Dinauer MC. A fluorescently tagged C-terminal fragment of p47phox detects NADPH oxidase dynamics during phagocytosis. Molecular Biology of the Cell. 20: 1520-32. PMID 19129478 DOI: 10.1091/Mbc.E08-06-0620 |
0.362 |
|
2008 |
von Löhneysen K, Noack D, Jesaitis AJ, Dinauer MC, Knaus UG. Mutational analysis reveals distinct features of the Nox4-p22 phox complex. The Journal of Biological Chemistry. 283: 35273-82. PMID 18849343 DOI: 10.1074/Jbc.M804200200 |
0.393 |
|
2008 |
Tian W, Li XJ, Stull ND, Ming W, Sun CI, Bissonnette SA, Yaffe MB, Grinstein S, Atkinson SJ, Dinauer MC. Fc{gamma}R-stimulated activation of the NADPH oxidase: Phosphoinositide- binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome Blood. 112: 3867-3877. PMID 18711001 DOI: 10.1182/Blood-2007-11-126029 |
0.377 |
|
2008 |
Gomez JC, Soltys J, Okano K, Dinauer MC, Doerschuk CM. The role of Rac2 in regulating neutrophil production in the bone marrow and circulating neutrophil counts. The American Journal of Pathology. 173: 507-17. PMID 18583316 DOI: 10.2353/Ajpath.2008.071059 |
0.353 |
|
2008 |
Hu G, Ye RD, Dinauer MC, Malik AB, Minshall RD. Neutrophil caveolin-1 expression contributes to mechanism of lung inflammation and injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L178-86. PMID 17993589 DOI: 10.1152/Ajplung.00263.2007 |
0.363 |
|
2008 |
Casbon AJ, Dunn KW, Allen L, Dinauer MC. NADPH oxidase flavocytochrome b localizes to Rab11‐positive recycling endosomes in macrophages The Faseb Journal. 22: 552-552. DOI: 10.1096/Fasebj.22.2_Supplement.552 |
0.753 |
|
2007 |
Li Y, Yan J, De P, Chang HC, Yamauchi A, Christopherson KW, Paranavitana NC, Peng X, Kim C, Munugalavadla V, Munugulavadla V, Kapur R, Chen H, Shou W, Stone JC, ... ... Dinauer MC, et al. Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins. Journal of Immunology (Baltimore, Md. : 1950). 179: 8322-31. PMID 18056377 DOI: 10.4049/Jimmunol.179.12.8322 |
0.427 |
|
2007 |
Cheng N, He R, Tian J, Dinauer MC, Ye RD. A critical role of protein kinase C delta activation loop phosphorylation in formyl-methionyl-leucyl-phenylalanine-induced phosphorylation of p47(phox) and rapid activation of nicotinamide adenine dinucleotide phosphate oxidase. Journal of Immunology (Baltimore, Md. : 1950). 179: 7720-8. PMID 18025218 DOI: 10.4049/Jimmunol.179.11.7720 |
0.379 |
|
2007 |
Broxmeyer HE, Mejia JA, Hangoc G, Barese C, Dinauer M, Cooper S. SDF-1/CXCL12 enhances in vitro replating capacity of murine and human multipotential and macrophage progenitor cells. Stem Cells and Development. 16: 589-96. PMID 17784832 DOI: 10.1089/Scd.2007.0044 |
0.349 |
|
2007 |
Grenda DS, Murakami M, Ghatak J, Xia J, Boxer LA, Dale D, Dinauer MC, Link DC. Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis. Blood. 110: 4179-87. PMID 17761833 DOI: 10.1182/Blood-2006-11-057299 |
0.33 |
|
2007 |
Chen J, He R, Minshall RD, Dinauer MC, Ye RD. Characterization of a mutation in the Phox homology domain of the NADPH oxidase component p40phox identifies a mechanism for negative regulation of superoxide production. The Journal of Biological Chemistry. 282: 30273-84. PMID 17698849 DOI: 10.1074/Jbc.M704416200 |
0.419 |
|
2007 |
Broxmeyer HE, Sehra S, Cooper S, Toney LM, Kusam S, Aloor JJ, Marchal CC, Dinauer MC, Dent AL. Aberrant regulation of hematopoiesis by T cells in BAZF-deficient mice. Molecular and Cellular Biology. 27: 5275-85. PMID 17526724 DOI: 10.1128/Mcb.01967-05 |
0.328 |
|
2007 |
Barese C, Pech N, Dirscherl S, Meyers JL, Sinn AL, Yoder MC, Goebel WS, Dinauer MC. Granulocyte colony-stimulating factor prior to nonmyeloablative irradiation decreases murine host hematopoietic stem cell function and increases engraftment of donor marrow cells. Stem Cells (Dayton, Ohio). 25: 1578-85. PMID 17347493 DOI: 10.1634/Stemcells.2006-0808 |
0.314 |
|
2007 |
Nakano Y, Banfi B, Jesaitis AJ, Dinauer MC, Allen LA, Nauseef WM. Critical roles for p22phox in the structural maturation and subcellular targeting of Nox3. The Biochemical Journal. 403: 97-108. PMID 17140397 DOI: 10.1042/Bj20060819 |
0.394 |
|
2007 |
Ming W, Li S, Billadeau DD, Quilliam LA, Dinauer MC. The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity. Molecular and Cellular Biology. 27: 312-23. PMID 17060455 DOI: 10.1128/Mcb.00985-06 |
0.392 |
|
2007 |
Murakami M, Xia J, Jordan CT, Boxer LA, Dale D, Bolyard AA, Dinauer MC, Link DC. Granulocytic Precursors from Patients with ELA2-Mutant Severe Congenital Neutropenia Display a Transcriptional Profile Consistent with Activation of the Unfolded Protein Response. Blood. 110: 662-662. DOI: 10.1182/Blood.V110.11.662.662 |
0.348 |
|
2006 |
Zhu Y, Marchal CC, Casbon AJ, Stull N, von Löhneysen K, Knaus UG, Jesaitis AJ, McCormick S, Nauseef WM, Dinauer MC. Deletion mutagenesis of p22phox subunit of flavocytochrome b558: identification of regions critical for gp91phox maturation and NADPH oxidase activity. The Journal of Biological Chemistry. 281: 30336-46. PMID 16895900 DOI: 10.1074/Jbc.M607191200 |
0.756 |
|
2006 |
Suh CI, Stull ND, Xing JL, Tian W, Price MO, Grinstein S, Yaffe MB, Atkinson S, Dinauer MC. The phosphoinositide-binding protein p40 phox activates the NADPH oxidase during FcγIIA receptor-induced phagocytosis Journal of Experimental Medicine. 203: 1915-1925. PMID 16880255 DOI: 10.1083/Jcb1744Oia8 |
0.624 |
|
2006 |
Pessach I, Shmelzer Z, Leto TL, Dinauer MC, Levy R. The C-terminal flavin domain of gp91phox bound to plasma membranes of granulocyte-like X-CGD PLB-985 cells is sufficient to anchor cytosolic oxidase components and support NADPH oxidase-associated diaphorase activity independent of cytosolic phospholipase A2 regulation. Journal of Leukocyte Biology. 80: 630-9. PMID 16844764 DOI: 10.1189/Jlb.1105684 |
0.402 |
|
2006 |
Okada F, Kobayashi M, Tanaka H, Kobayashi T, Tazawa H, Iuchi Y, Onuma K, Hosokawa M, Dinauer MC, Hunt NH. The role of nicotinamide adenine dinucleotide phosphate oxidase-derived reactive oxygen species in the acquisition of metastatic ability of tumor cells. The American Journal of Pathology. 169: 294-302. PMID 16816381 DOI: 10.2353/Ajpath.2006.060073 |
0.31 |
|
2006 |
Kim C, Dinauer MC. Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid. Journal of Leukocyte Biology. 79: 223-34. PMID 16275890 DOI: 10.1189/Jlb.0705371 |
0.406 |
|
2006 |
Martyn KD, Frederick LM, von Loehneysen K, Dinauer MC, Knaus UG. Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases. Cellular Signalling. 18: 69-82. PMID 15927447 DOI: 10.1016/J.Cellsig.2005.03.023 |
0.397 |
|
2006 |
Li XJ, Tian W, Casbon AJ, Atkinson SJ, Dinauer MC. 39 Fluorescently Tagged Proteins to Monitor NADPH Oxidase Assembly During Phagocytosis Pediatric Research. 60: 497-497. DOI: 10.1203/00006450-200610000-00061 |
0.411 |
|
2006 |
Tian W, Li XJ, Stull ND, Suh C, Grinstein S, Yaffe MB, Atkinson SJ, Dinauer MC. The Phosphoinositide-Binding Protein p40phox Regulates NADPH Oxidase Activation Rather Than Assembly during FcγIIA Receptor-Induced Phagocytosis. Blood. 108: 678-678. DOI: 10.1182/Blood.V108.11.678.678 |
0.379 |
|
2006 |
Sadat M, Dirscherl S, Pech N, Getty R, Cross S, Barese C, Goebel WS, Yoder MC, Mooney S, Grez M, Cornetta K, Dinauer MC. Biased Engraftment of Retrovirus-Transduced Marrow in Murine X-CGD Following Submyeloablative Conditioning. Blood. 108: 3285-3285. DOI: 10.1182/Blood.V108.11.3285.3285 |
0.332 |
|
2005 |
Dinauer MC. Chronic granulomatous disease and other disorders of phagocyte function. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 89-95. PMID 16304364 DOI: 10.1182/Asheducation-2005.1.89 |
0.325 |
|
2005 |
Goebel WS, Mark LA, Billings SD, Meyers JL, Pech N, Travers JB, Dinauer MC. Gene correction reduces cutaneous inflammation and granuloma formation in murine X-linked chronic granulomatous disease. The Journal of Investigative Dermatology. 125: 705-10. PMID 16185269 DOI: 10.1111/J.0022-202X.2005.23908.X |
0.342 |
|
2005 |
Matute JD, Arias AA, Dinauer MC, Patiño PJ. p40phox: the last NADPH oxidase subunit. Blood Cells, Molecules & Diseases. 35: 291-302. PMID 16102984 DOI: 10.1016/J.Bcmd.2005.06.010 |
0.395 |
|
2005 |
Martyn KD, Kim MJ, Quinn MT, Dinauer MC, Knaus UG. p21-activated kinase (Pak) regulates NADPH oxidase activation in human neutrophils. Blood. 106: 3962-9. PMID 16099876 DOI: 10.1182/Blood-2005-03-0859 |
0.41 |
|
2005 |
Potter SM, Mitchell AJ, Cowden WB, Sanni LA, Dinauer M, de Haan JB, Hunt NH. Phagocyte-derived reactive oxygen species do not influence the progression of murine blood-stage malaria infections. Infection and Immunity. 73: 4941-7. PMID 16041008 DOI: 10.1128/Iai.73.8.4941-4947.2005 |
0.33 |
|
2005 |
Carstanjen D, Yamauchi A, Koornneef A, Zang H, Filippi MD, Harris C, Towe J, Atkinson S, Zheng Y, Dinauer MC, Williams DA. Rac2 regulates neutrophil chemotaxis, superoxide production, and myeloid colony formation through multiple distinct effector pathways. Journal of Immunology (Baltimore, Md. : 1950). 174: 4613-20. PMID 15814684 DOI: 10.4049/Jimmunol.174.8.4613 |
0.358 |
|
2005 |
Baniulis D, Burritt JB, Taylor RM, Dinauer MC, Heyworth PG, Parkos CA, Magnusson KE, Jesaitis AJ. Monoclonal antibody CL5 recognizes the amino terminal domain of human phagocyte flavocytochrome b558 large subunit, gp91phox. European Journal of Haematology. 74: 337-47. PMID 15777347 DOI: 10.1111/J.1600-0609.2004.00380.X |
0.358 |
|
2005 |
Baniulis D, Nauseef WM, Burritt JB, Taylor RM, Heyworth PG, Dinauer MC, Bumelis VA, Magnusson KE, Jesaitis AJ. Unusual polyclonal anti-gp91 peptide antibody interactions with X-linked chronic granulomatous disease-derived human neutrophils are not from compensatory expression of Nox proteins 1, 3, or 4. European Journal of Haematology. 74: 241-9. PMID 15693794 DOI: 10.1111/J.1600-0609.2004.00357.X |
0.305 |
|
2005 |
Yamauchi A, Marchal CC, Molitoris J, Pech N, Knaus U, Towe J, Atkinson SJ, Dinauer MC. Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain. The Journal of Biological Chemistry. 280: 953-64. PMID 15504745 DOI: 10.1074/Jbc.M408820200 |
0.411 |
|
2005 |
Sadat M, Barese C, Pech N, Goebel WS, Yoder MC, Mooney S, Cornetta K, Grez M, Dinauer MC. Reconstitution of Neutrophil NADPH Oxidase Activity in Murine X-CGD Following Transplantation of Retrovirus-Transduced Marrow: Potential Impact of Submyeloablative Conditioning. Blood. 106: 3050-3050. DOI: 10.1182/Blood.V106.11.3050.3050 |
0.338 |
|
2004 |
He R, Nanamori M, Sang H, Yin H, Dinauer MC, Ye RD. Reconstitution of chemotactic peptide-induced nicotinamide adenine dinucleotide phosphate (reduced) oxidase activation in transgenic COS-phox cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 7462-70. PMID 15585872 DOI: 10.4049/Jimmunol.173.12.7462 |
0.406 |
|
2004 |
Taylor RM, Burritt JB, Baniulis D, Foubert TR, Lord CI, Dinauer MC, Parkos CA, Jesaitis AJ. Site-specific inhibitors of NADPH oxidase activity and structural probes of flavocytochrome b: characterization of six monoclonal antibodies to the p22phox subunit. Journal of Immunology (Baltimore, Md. : 1950). 173: 7349-57. PMID 15585859 DOI: 10.4049/Jimmunol.173.12.7349 |
0.349 |
|
2004 |
Arias AA, Dinauer MC, Ding J, Matute JD, Patiño PJ. [Expression and activity of polymorphisms in the 67-kDa protein of the NADPH oxidase system]. BioméDica : Revista Del Instituto Nacional De Salud. 24: 262-72. PMID 15551878 |
0.316 |
|
2004 |
Yamauchi A, Kim C, Li S, Marchal CC, Towe J, Atkinson SJ, Dinauer MC. Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles. Journal of Immunology (Baltimore, Md. : 1950). 173: 5971-9. PMID 15528331 DOI: 10.4049/Jimmunol.173.10.5971 |
0.403 |
|
2004 |
Goebel WS, Pech NK, Dinauer MC. Stable long-term gene correction with low-dose radiation conditioning in murine X-linked chronic granulomatous disease. Blood Cells, Molecules & Diseases. 33: 365-71. PMID 15528159 DOI: 10.1016/J.Bcmd.2004.06.007 |
0.314 |
|
2004 |
Barese CN, Goebel WS, Dinauer MC. Gene therapy for chronic granulomatous disease. Expert Opinion On Biological Therapy. 4: 1423-34. PMID 15335310 DOI: 10.1067/Mlc.2000.104458 |
0.314 |
|
2004 |
Kobayashi T, Ogawa Y, Watanabe Y, Furuya M, Kataoka S, Garcia del Saz E, Tsunawaki S, Dinauer MC, Seguchi H. Mitochondrial transmembrane potential is diminished in phorbol myristate acetate-stimulated peritoneal resident macrophages isolated from wild-type mice, but not in those from gp91-phox-deficient mice. Histochemistry and Cell Biology. 122: 323-32. PMID 15243751 DOI: 10.1007/S00418-004-0674-0 |
0.382 |
|
2004 |
Diebold BA, Fowler B, Lu J, Dinauer MC, Bokoch GM. Antagonistic cross-talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species. The Journal of Biological Chemistry. 279: 28136-42. PMID 15123662 DOI: 10.1074/Jbc.M313891200 |
0.414 |
|
2004 |
Abdel-Latif D, Steward M, Macdonald DL, Francis GA, Dinauer MC, Lacy P. Rac2 is critical for neutrophil primary granule exocytosis. Blood. 104: 832-9. PMID 15073033 DOI: 10.1182/Blood-2003-07-2624 |
0.378 |
|
2004 |
Suh CI, Stull N, Fuji Y, Grinstein S, Yaffe M, Atkinson S, Dinauer MC. Role for p40phox in Fcγ-Receptor-Induced NADPH Oxidase Activation. Blood. 104: 653-653. DOI: 10.1182/Blood.V104.11.653.653 |
0.468 |
|
2004 |
Kim C, Dinauer MC. Arachidonic Acid Rescues Defects on PMA-Elicited NADPH Oxidase Activity in Rac2-Deficient Neutrophils. Blood. 104: 2386-2386. DOI: 10.1182/Blood.V104.11.2386.2386 |
0.383 |
|
2004 |
Arias AA, Matute JD, Patino PJ, Dinauer MC. Analysis of a p67phoxΔ401 Mutant Identified in Chronic Granulomatous Disease: Deletion of C-Terminal SH3 Binding Site for p47phox Still Supports NADPH Oxidase Activity in Cosphox Cells. Blood. 104: 2381-2381. DOI: 10.1182/Blood.V104.11.2381.2381 |
0.415 |
|
2004 |
Barese CN, Goebel WS, Pech NK, Meyers J, Dinauer MC. Granulocyte Colony-Stimulating Factor Prior to Low-Dose Total Body Irradiation as Conditioning Regimen in Hematopoietic Stem Cell Transplantation for Gene Therapy. Blood. 104: 1193-1193. DOI: 10.1182/Blood.V104.11.1193.1193 |
0.309 |
|
2003 |
Goebel WS, Dinauer MC. Gene therapy for chronic granulomatous disease. Acta Haematologica. 110: 86-92. PMID 14583668 DOI: 10.1159/000072457 |
0.341 |
|
2003 |
Kim C, Marchal CC, Penninger J, Dinauer MC. The hemopoietic Rho/Rac guanine nucleotide exchange factor Vav1 regulates N-formyl-methionyl-leucyl-phenylalanine-activated neutrophil functions. Journal of Immunology (Baltimore, Md. : 1950). 171: 4425-30. PMID 14530369 DOI: 10.4049/Jimmunol.171.8.4425 |
0.393 |
|
2003 |
Sadat MA, Pech N, Saulnier S, Leroy BA, Hossle JP, Grez M, Dinauer MC. Long-term high-level reconstitution of NADPH oxidase activity in murine X-linked chronic granulomatous disease using a bicistronic vector expressing gp91phox and a Delta LNGFR cell surface marker. Human Gene Therapy. 14: 651-66. PMID 12804147 DOI: 10.1089/104303403321618164 |
0.384 |
|
2003 |
Glogauer M, Marchal CC, Zhu F, Worku A, Clausen BE, Foerster I, Marks P, Downey GP, Dinauer M, Kwiatkowski DJ. Rac1 deletion in mouse neutrophils has selective effects on neutrophil functions. Journal of Immunology (Baltimore, Md. : 1950). 170: 5652-7. PMID 12759446 DOI: 10.4049/Jimmunol.170.11.5652 |
0.422 |
|
2003 |
Dinauer MC. Regulation of neutrophil function by Rac GTPases. Current Opinion in Hematology. 10: 8-15. PMID 12483106 DOI: 10.1097/00062752-200301000-00003 |
0.355 |
|
2002 |
Aratani Y, Kura F, Watanabe H, Akagawa H, Takano Y, Suzuki K, Dinauer MC, Maeda N, Koyama H. Relative contributions of myeloperoxidase and NADPH-oxidase to the early host defense against pulmonary infections with Candida albicans and Aspergillus fumigatus Medical Mycology. 40: 557-563. PMID 12521119 DOI: 10.1080/Mmy.40.6.557.563 |
0.357 |
|
2002 |
Goebel WS, Dinauer MC. Retroviral-mediated gene transfer and nonmyeloablative conditioning: studies in a murine X-linked chronic granulomatous disease model. Journal of Pediatric Hematology/Oncology. 24: 787-90. PMID 12468930 DOI: 10.1097/00043426-200212000-00026 |
0.326 |
|
2002 |
Li S, Yamauchi A, Marchal CC, Molitoris JK, Quilliam LA, Dinauer MC. Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions. Journal of Immunology (Baltimore, Md. : 1950). 169: 5043-51. PMID 12391220 DOI: 10.4049/Jimmunol.169.9.5043 |
0.415 |
|
2002 |
Aratani Y, Kura F, Watanabe H, Akagawa H, Takano Y, Suzuki K, Dinauer MC, Maeda N, Koyama H. Critical role of myeloperoxidase and nicotinamide adenine dinucleotide phosphate-oxidase in high-burden systemic infection of mice with Candida albicans. The Journal of Infectious Diseases. 185: 1833-7. PMID 12085336 DOI: 10.1086/340635 |
0.3 |
|
2002 |
Biberstine-Kinkade KJ, Yu L, Stull N, LeRoy B, Bennett S, Cross A, Dinauer MC. Mutagenesis of p22(phox) histidine 94. A histidine in this position is not required for flavocytochrome b558 function. The Journal of Biological Chemistry. 277: 30368-74. PMID 12042318 DOI: 10.1074/Jbc.M203993200 |
0.398 |
|
2002 |
Morgan D, Cherny VV, Price MO, Dinauer MC, DeCoursey TE. Absence of proton channels in COS-7 cells expressing functional NADPH oxidase components. The Journal of General Physiology. 119: 571-80. PMID 12034764 DOI: 10.1085/Jgp.20018544 |
0.573 |
|
2002 |
Gao XP, Standiford TJ, Rahman A, Newstead M, Holland SM, Dinauer MC, Liu QH, Malik AB. Role of NADPH oxidase in the mechanism of lung neutrophil sequestration and microvessel injury induced by Gram-negative sepsis: studies in p47phox-/- and gp91phox-/- mice. Journal of Immunology (Baltimore, Md. : 1950). 168: 3974-82. PMID 11937554 DOI: 10.4049/Jimmunol.168.8.3974 |
0.337 |
|
2002 |
Price MO, McPhail LC, Lambeth JD, Han CH, Knaus UG, Dinauer MC. Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system. Blood. 99: 2653-61. PMID 11929750 DOI: 10.1182/Blood.V99.8.2653 |
0.627 |
|
2002 |
Price MO, Atkinson SJ, Knaus UG, Dinauer MC. Rac activation induces NADPH oxidase activity in transgenic COSphox cells, and the level of superoxide production is exchange factor-dependent. The Journal of Biological Chemistry. 277: 19220-8. PMID 11896053 DOI: 10.1074/Jbc.M200061200 |
0.629 |
|
2002 |
Petersen JE, Hiran TS, Goebel WS, Johnson C, Murphy RC, Azmi FH, Hood AF, Travers JB, Dinauer MC. Enhanced cutaneous inflammatory reactions to Aspergillus fumigatus in a murine model of chronic granulomatous disease Journal of Investigative Dermatology. 118: 424-429. PMID 11874480 DOI: 10.1046/J.0022-202X.2001.01691.X |
0.354 |
|
2001 |
Hiran T, Dinauer M, Johnson C, Clay K, Travers J. Evidence for the involvement of the NADPH oxidase enzyme complex in the optimal accumulation of Platelet-activating factor in the human cell line PLB-985. Prostaglandins & Other Lipid Mediators. 66: 305-15. PMID 11785782 DOI: 10.1016/S0090-6980(01)00163-0 |
0.398 |
|
2001 |
DeCoursey TE, Cherny VV, Morgan D, Katz BZ, Dinauer MC. The gp91phox component of NADPH oxidase is not the voltage-gated proton channel in phagocytes, but it helps. The Journal of Biological Chemistry. 276: 36063-6. PMID 11477065 DOI: 10.1074/Jbc.C100352200 |
0.347 |
|
2001 |
Biberstine-Kinkade KJ, DeLeo FR, Epstein RI, LeRoy BA, Nauseef WM, Dinauer MC. Heme-ligating histidines in flavocytochrome b(558): identification of specific histidines in gp91(phox). The Journal of Biological Chemistry. 276: 31105-12. PMID 11413138 DOI: 10.1074/Jbc.M103327200 |
0.398 |
|
2001 |
Dinauer MC, Gifford MA, Pech N, Li LL, Emshwiller P. Variable correction of host defense following gene transfer and bone marrow transplantation in murine X-linked chronic granulomatous disease. Blood. 97: 3738-45. PMID 11389011 DOI: 10.1182/Blood.V97.12.3738 |
0.355 |
|
2001 |
Yamauchi A, Yu L, Pötgens AJ, Kuribayashi F, Nunoi H, Kanegasaki S, Roos D, Malech HL, Dinauer MC, Nakamura M. Location of the epitope for 7D5, a monoclonal antibody raised against human flavocytochrome b558, to the extracellular peptide portion of primate gp91phox. Microbiology and Immunology. 45: 249-57. PMID 11345535 DOI: 10.1111/J.1348-0421.2001.Tb02614.X |
0.326 |
|
2001 |
Kim C, Dinauer MC. Rac2 is an essential regulator of neutrophil nicotinamide adenine dinucleotide phosphate oxidase activation in response to specific signaling pathways. Journal of Immunology (Baltimore, Md. : 1950). 166: 1223-32. PMID 11145705 DOI: 10.4049/Jimmunol.166.2.1223 |
0.405 |
|
2001 |
van Reyk DM, King NJ, Dinauer MC, Hunt NH. The intracellular oxidation of 2',7'-dichlorofluorescin in murine T lymphocytes. Free Radical Biology & Medicine. 30: 82-8. PMID 11134898 DOI: 10.1016/S0891-5849(00)00449-4 |
0.344 |
|
2001 |
Burritt JB, DeLeo FR, McDonald CL, Prigge JR, Dinauer MC, Nakamura M, Nauseef WM, Jesaitis AJ. Phage display epitope mapping of human neutrophil flavocytochrome b558. Identification of two juxtaposed extracellular domains. The Journal of Biological Chemistry. 276: 2053-61. PMID 11027685 DOI: 10.1074/Jbc.M006236200 |
0.366 |
|
2000 |
Dinauer MC, Lekstrom-Himes JA, Dale DC. Inherited Neutrophil Disorders: Molecular Basis and New Therapies. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 303-318. PMID 11701548 DOI: 10.1182/Asheducation-2000.1.303 |
0.362 |
|
2000 |
Saulnier SO, Steinhoff D, Dinauer MC, Zufferey R, Trono D, Seger RA, Hossle JP. Lentivirus-mediated gene transfer of gp91phox corrects chronic granulomatous disease (CGD) phenotype in human X-CGD cells. The Journal of Gene Medicine. 2: 317-25. PMID 11045425 DOI: 10.1002/1521-2254(200009/10)2:5<317::Aid-Jgm127>3.0.Co;2-P |
0.345 |
|
2000 |
Kirk EA, Dinauer MC, Rosen H, Chait A, Heinecke JW, LeBoeuf RC. Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 1529-35. PMID 10845868 DOI: 10.1161/01.Atv.20.6.1529 |
0.364 |
|
2000 |
Yang FC, Kapur R, King AJ, Tao W, Kim C, Borneo J, Breese R, Marshall M, Dinauer MC, Williams DA. Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells. Immunity. 12: 557-68. PMID 10843388 DOI: 10.1016/S1074-7613(00)80207-1 |
0.361 |
|
2000 |
DeLeo FR, Burritt JB, Yu L, Jesaitis AJ, Dinauer MC, Nauseef WM. Processing and maturation of flavocytochrome b558 include incorporation of heme as a prerequisite for heterodimer assembly. The Journal of Biological Chemistry. 275: 13986-93. PMID 10788525 DOI: 10.1074/Jbc.275.18.13986 |
0.353 |
|
2000 |
Vazquez-Torres A, Xu Y, Jones-Carson J, Holden DW, Lucia SM, Dinauer MC, Mastroeni P, Fang FC. Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase. Science (New York, N.Y.). 287: 1655-8. PMID 10698741 DOI: 10.1126/Science.287.5458.1655 |
0.382 |
|
2000 |
Zentilin L, Qin G, Tafuro S, Dinauer MC, Baum C, Giacca M. Variegation of retroviral vector gene expression in myeloid cells. Gene Therapy. 7: 153-66. PMID 10673720 DOI: 10.1038/Sj.Gt.3301057 |
0.352 |
|
2000 |
Ozaki M, Deshpande SS, Angkeow P, Bellan J, Lowenstein CJ, Dinauer MC, Goldschmidt-Clermont PJ, Irani K. Inhibition of the Rac1 GTPase protects against nonlethal ischemia/reperfusion-induced necrosis and apoptosis in vivo Faseb Journal. 14: 418-429. PMID 10657998 DOI: 10.1096/Fasebj.14.2.418 |
0.31 |
|
2000 |
Williams DA, Tao W, Yang F, Kim C, Gu Y, Mansfield P, Levine JE, Petryniak B, Derrow CW, Harris C, Jia B, Zheng Y, Ambruso DR, Lowe JB, Atkinson SJ, ... Dinauer MC, et al. Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency Blood. 96: 1646-1654. DOI: 10.1182/Blood.V96.5.1646.H8001646_1646_1654 |
0.396 |
|
2000 |
Dinauer MC, Lekstrom-Himes JA, Dale DC. Inherited Neutrophil Disorders Hematology. 2000: 303-318. DOI: 10.1182/Asheducation.V2000.1.303.20000303 |
0.365 |
|
2000 |
Goebel W, Pech N, Dinauer MC. Donor chimerism and gene correction with low dose irradiation and retroviral-mediated gene transfer (Rmgt) In murine x-linked chronic granulomatous disease (X-cgd) Experimental Hematology. 28: 1499-1500. DOI: 10.1016/S0301-472X(00)00580-4 |
0.322 |
|
1999 |
Archer SL, Reeve HL, Michelakis E, Puttagunta L, Waite R, Nelson DP, Dinauer MC, Weir EK. O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase. Proceedings of the National Academy of Sciences of the United States of America. 96: 7944-9. PMID 10393927 DOI: 10.1073/Pnas.96.14.7944 |
0.328 |
|
1999 |
Nicholson SC, Grobmyer SR, Shiloh MU, Brause JE, Potter S, MacMicking JD, Dinauer MC, Nathan CF. Lethality of endotoxin in mice genetically deficient in the respiratory burst oxidase, inducible nitric oxide synthase, or both. Shock (Augusta, Ga.). 11: 253-8. PMID 10220301 DOI: 10.1097/00024382-199904000-00005 |
0.369 |
|
1999 |
Biberstine-Kinkade KJ, Yu L, Dinauer MC. Mutagenesis of an arginine- and lysine-rich domain in the gp91(phox) subunit of the phagocyte NADPH-oxidase flavocytochrome b558. The Journal of Biological Chemistry. 274: 10451-7. PMID 10187835 DOI: 10.1074/Jbc.274.15.10451 |
0.406 |
|
1999 |
Ou X, Pollock J, Dinauer MC, Gharehbaghi-Schnell E, Skalnik DG. Identification and functional characterization of the murine Rac2 gene promoter Dna and Cell Biology. 18: 253-263. PMID 10098607 DOI: 10.1089/104454999315475 |
0.31 |
|
1999 |
Roberts AW, Kim C, Zhen L, Lowe JB, Kapur R, Petryniak B, Spaetti A, Pollock JD, Borneo JB, Bradford GB, Atkinson SJ, Dinauer MC, Williams DA. Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense. Immunity. 10: 183-96. PMID 10072071 DOI: 10.1016/S1074-7613(00)80019-9 |
0.42 |
|
1999 |
Shiloh MU, MacMicking JD, Nicholson S, Brause JE, Potter S, Marino M, Fang F, Dinauer M, Nathan C. Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase. Immunity. 10: 29-38. PMID 10023768 DOI: 10.1016/S1074-7613(00)80004-7 |
0.386 |
|
1999 |
Yu L, DeLeo FR, Biberstine-Kinkade KJ, Renee J, Nauseef WM, Dinauer MC. Biosynthesis of flavocytochrome b558 . gp91(phox) is synthesized as a 65-kDa precursor (p65) in the endoplasmic reticulum. The Journal of Biological Chemistry. 274: 4364-9. PMID 9933639 DOI: 10.1074/Jbc.274.7.4364 |
0.343 |
|
1999 |
Lundberg BE, Wolf RE, Dinauer MC, Xu Y, Fang FC. Glucose 6-phosphate dehydrogenase is required for Salmonella typhimurium virulence and resistance to reactive oxygen and nitrogen intermediates. Infection and Immunity. 67: 436-8. PMID 9864251 DOI: 10.1128/Iai.67.1.436-438.1999 |
0.343 |
|
1999 |
Sanni LA, Fu S, Dean RT, Bloomfield G, Stocker R, Chaudhri G, Dinauer MC, Hunt NH. Are reactive oxygen species involved in the pathogenesis of murine cerebral malaria? The Journal of Infectious Diseases. 179: 217-22. PMID 9841842 DOI: 10.1086/314552 |
0.313 |
|
1999 |
Yu L, Cross AR, Zhen L, Dinauer MC. Functional Analysis of NADPH Oxidase in Granulocytic Cells Expressing a ▵488-497 gp91phox Deletion Mutant Blood. 94: 2497-2504. DOI: 10.1182/Blood.V94.7.2497.419K11_2497_2504 |
0.413 |
|
1999 |
Dinauer MC, Li LL, Björgvinsdóttir H, Ding C, Pech N. Long-Term Correction of Phagocyte NADPH Oxidase Activity by Retroviral-Mediated Gene Transfer in Murine X-Linked Chronic Granulomatous Disease Blood. 94: 914-922. DOI: 10.1182/Blood.V94.3.914.415A11_914_922 |
0.399 |
|
1998 |
Li LL, Dinauer MC. Reconstitution of NADPH oxidase activity in human X-linked chronic granulomatous disease myeloid cells after stable gene transfer using a recombinant adeno-associated virus 2 vector Blood Cells Molecules and Diseases. 24: 522-538. PMID 9880243 DOI: 10.1006/Bcmd.1998.0216 |
0.375 |
|
1998 |
Al-Mehdi AB, Zhao G, Dodia C, Tozawa K, Costa K, Muzykantov V, Ross C, Blecha F, Dinauer M, Fisher AB. Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+ Circulation Research. 83: 730-737. PMID 9758643 DOI: 10.1161/01.Res.83.7.730 |
0.307 |
|
1998 |
Becker S, Wasser S, Hauses M, Hossle JP, Ott MG, Dinauer MC, Ganser A, Hoelzer D, Seger R, Grez M. Correction of respiratory burst activity in X-linked chronic granulomatous cells to therapeutically relevant levels after gene transfer into bone marrow CD34+ cells. Human Gene Therapy. 9: 1561-70. PMID 9694155 DOI: 10.1089/Hum.1998.9.11-1561 |
0.352 |
|
1998 |
Yu L, Quinn MT, Cross AR, Dinauer MC. Gp91(phox) is the heme binding subunit of the superoxide-generating NADPH oxidase. Proceedings of the National Academy of Sciences of the United States of America. 95: 7993-8. PMID 9653128 DOI: 10.1073/Pnas.95.14.7993 |
0.413 |
|
1998 |
Zhen L, Yu L, Dinauer MC. Probing the role of the carboxyl terminus of the gp91phox subunit of neutrophil flavocytochrome b558 using site-directed mutagenesis. The Journal of Biological Chemistry. 273: 6575-81. PMID 9497394 DOI: 10.1074/Jbc.273.11.6575 |
0.404 |
|
1997 |
De Groote MA, Ochsner UA, Shiloh MU, Nathan C, McCord JM, Dinauer MC, Libby SJ, Vazquez-Torres A, Xu Y, Fang FC. Periplasmic superoxide dismutase protects Salmonella from products of phagocyte NADPH-oxidase and nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 94: 13997-4001. PMID 9391141 DOI: 10.1073/Pnas.94.25.13997 |
0.343 |
|
1997 |
Yu L, Zhen L, Dinauer MC. Biosynthesis of the phagocyte NADPH oxidase cytochrome b558. Role of heme incorporation and heterodimer formation in maturation and stability of gp91phox and p22phox subunits. The Journal of Biological Chemistry. 272: 27288-94. PMID 9341176 DOI: 10.1074/Jbc.272.43.27288 |
0.414 |
|
1997 |
Morgenstern DE, Gifford MA, Li LL, Doerschuk CM, Dinauer MC. Absence of respiratory burst in X-linked chronic granulomatous disease mice leads to abnormalities in both host defense and inflammatory response to Aspergillus fumigatus. The Journal of Experimental Medicine. 185: 207-18. PMID 9016870 DOI: 10.1084/Jem.185.2.207 |
0.352 |
|
1997 |
Björgvinsdóttir H, Ding C, Pech N, Gifford MA, Li LL, Dinauer MC. Retroviral-Mediated Gene Transfer of gp91phox Into Bone Marrow Cells Rescues Defect in Host Defense Against Aspergillus fumigatus in Murine X-Linked Chronic Granulomatous Disease Blood. 89: 41-48. DOI: 10.1182/Blood.V89.1.41.41_41_48 |
0.376 |
|
1996 |
Wang D, Youngson C, Wong V, Yeger H, Dinauer MC, Vega-Saenz De Miera E, Rudy B, Cutz E. NADPH-oxidase and a hydrogen peroxide-sensitive K+ channel may function as an oxygen sensor complex in airway chemoreceptors and small cell lung carcinoma cell lines Proceedings of the National Academy of Sciences of the United States of America. 93: 13182-13187. PMID 8917565 DOI: 10.1073/Pnas.93.23.13182 |
0.343 |
|
1996 |
Kubo H, Morgenstern D, Quinian WM, Ward PA, Dinauer MC, Doerschuk CM. Preservation of complement-induced lung injury in mice with deficiency of NADPH oxidase. The Journal of Clinical Investigation. 97: 2680-4. PMID 8647963 DOI: 10.1172/Jci118718 |
0.323 |
|
1996 |
Ding C, Kume A, Bjorgvinsdottir H, Hawley R, Pech N, Dinauer M. High-level reconstitution of respiratory burst activity in a human X- linked chronic granulomatous disease (X-CGD) cell line and correction of murine X-CGD bone marrow cells by retroviral-mediated gene transfer of human gp91phox Blood. 88: 1834-1840. DOI: 10.1182/Blood.V88.5.1834.Bloodjournal8851834 |
0.386 |
|
1996 |
Bjorgvinsdottir H, Zhen L, Dinauer M. Cloning of murine gp91phox cDNA and functional expression in a human X- linked chronic granulomatous disease cell line Blood. 87: 2005-2010. DOI: 10.1182/Blood.V87.5.2005.2005 |
0.384 |
|
1995 |
Pollock JD, Williams DA, Gifford MA, Li LL, Du X, Fisherman J, Orkin SH, Doerschuk CM, Dinauer MC. Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production. Nature Genetics. 9: 202-9. PMID 7719350 DOI: 10.1038/Ng0295-202 |
0.389 |
|
1994 |
Newburger P, Malawista S, Dinauer M, Gelbart T, Woodman R, Chada S, Shen Q, van Blaricom G, Quie P, Curnutte J. Chronic granulomatous disease and glutathione peroxidase deficiency, revisited Blood. 84: 3861-3869. DOI: 10.1182/Blood.V84.11.3861.Bloodjournal84113861 |
0.399 |
|
1994 |
Kume A, Dinauer M. Retrovirus-mediated reconstitution of respiratory burst activity in X- linked chronic granulomatous disease cells Blood. 84: 3311-3316. DOI: 10.1182/Blood.V84.10.3311.3311 |
0.378 |
|
1993 |
Maly FE, Schuerer-Maly CC, Quilliam L, Cochrane CG, Newburger PE, Curnutte JT, Gifford M, Dinauer MC. Restitution of superoxide generation in autosomal cytochrome-negative chronic granulomatous disease (A22(0) CGD)-derived B lymphocyte cell lines by transfection with p22phax cDNA. The Journal of Experimental Medicine. 178: 2047-53. PMID 8245781 DOI: 10.1084/Jem.178.6.2047 |
0.4 |
|
1993 |
Zhen L, King AA, Xiao Y, Chanock SJ, Orkin SH, Dinauer MC. Gene targeting of X chromosome-linked chronic granulomatous disease locus in a human myeloid leukemia cell line and rescue by expression of recombinant gp91phox. Proceedings of the National Academy of Sciences of the United States of America. 90: 9832-6. PMID 8234321 DOI: 10.1073/Pnas.90.21.9832 |
0.361 |
|
1991 |
Dinauer MC, Pierce EA, Erickson RW, Muhlebach TJ, Messner H, Orkin SH, Seger RA, Curnutte JT. Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease. Proceedings of the National Academy of Sciences of the United States of America. 88: 11231-5. PMID 1763037 DOI: 10.1073/Pnas.88.24.11231 |
0.409 |
|
1990 |
Dinauer MC, Pierce EA, Bruns GA, Curnutte JT, Orkin SH. Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease. The Journal of Clinical Investigation. 86: 1729-37. PMID 2243141 DOI: 10.1172/Jci114898 |
0.323 |
|
1990 |
Ezekowitz R, Sieff C, Dinauer M, Nathan D, Orkin S, Newburger P. Restoration of phagocyte function by interferon-gamma in X-linked chronic granulomatous disease occurs at the level of a progenitor cell Blood. 76: 2443-2448. DOI: 10.1182/Blood.V76.12.2443.2443 |
0.37 |
|
1989 |
Parkos CA, Dinauer MC, Jesaitis AJ, Orkin SH, Curnutte JT. Absence of both the 91kD and 22kD subunits of human neutrophil cytochrome b in two genetic forms of chronic granulomatous disease Blood. 73: 1416-1420. PMID 2713485 DOI: 10.1182/Blood.V73.6.1416.Bloodjournal7361416 |
0.379 |
|
1989 |
Dinauer MC, Curnutte JT, Rosen H, Orkin SH. A missense mutation in the neutrophil cytochrome b heavy chain in cytochrome-positive X-linked chronic granulomatous disease Journal of Clinical Investigation. 84: 2012-2016. PMID 2556453 DOI: 10.1172/Jci114393 |
0.357 |
|
1989 |
Quinn MT, Parkos CA, Walker L, Orkin SH, Dinauer MC, Jesaitis AJ. Association of a Ras-related protein with cytochrome b of human neutrophils Nature. 342: 198-200. PMID 2509942 DOI: 10.1038/342198A0 |
0.307 |
|
1988 |
Parkos CA, Dinauer MC, Walker LE, Allen RA, Jesaitis AJ, Orkin SH. Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b Proceedings of the National Academy of Sciences of the United States of America. 85: 3319-3323. PMID 3368442 DOI: 10.1073/Pnas.85.10.3319 |
0.375 |
|
1988 |
Ezekowitz RA, Dinauer MC, Jaffe HS, Orkin SH, Newburger PE. Partial correction of the phagocyte defect in patients with X-linked chronic granulomatous disease by subcutaneous interferon gamma. The New England Journal of Medicine. 319: 146-51. PMID 2838754 DOI: 10.1056/Nejm198807213190305 |
0.381 |
|
1987 |
Dinauer MC, Orkin SH, Brown R, Jesaitis AJ, Parkos CA. The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex Nature. 327: 717-720. PMID 3600768 DOI: 10.1038/327717A0 |
0.354 |
|
Show low-probability matches. |