| Year |
Citation |
Score |
| 2024 |
Kumari N, Ahmad A, Berto-Junior C, Ivanov A, Wen F, Lin X, Diaz S, Okpala I, Taylor JG, Jerebtsova M, Nekhai S. Antiviral response and HIV-1 inhibition in sickle cell disease. Iscience. 27: 108813. PMID 38318349 DOI: 10.1016/j.isci.2024.108813 |
0.459 |
|
| 2023 |
Ogundiran AI, Chang TL, Ivanov A, Kumari N, Nekhai S, Chandran PL. Shear-reversible clusters of HIV-1 in solution: stabilized by antibodies, dispersed by mucin. Journal of Virology. e0075223. PMID 37712704 DOI: 10.1128/jvi.00752-23 |
0.303 |
|
| 2022 |
Lin X, Ahmad A, Ivanov AI, Simhadri J, Wang S, Kumari N, Ammosova T, Nekhai S. HIV-1 Transcription Inhibitor 1E7-03 Decreases Nucleophosmin (NPM1) Phosphorylation. Molecular & Cellular Proteomics : McP. 100488. PMID 36563749 DOI: 10.1016/j.mcpro.2022.100488 |
0.459 |
|
| 2022 |
Nekhai S, Kumari N. HIV-1 infection in sickle cell disease and sickle cell trait: role of iron and innate response. Expert Review of Hematology. 15: 253-263. PMID 35322747 DOI: 10.1080/17474086.2022.2054799 |
0.411 |
|
| 2021 |
Pushkarsky T, Ward A, Ivanov A, Lin X, Sviridov D, Nekhai S, Bukrinsky MI. Abundance of Nef and p-Tau217 in Brains of Individuals Diagnosed with HIV-Associated Neurocognitive Disorders Correlate with Disease Severance. Molecular Neurobiology. PMID 34843091 DOI: 10.1007/s12035-021-02608-2 |
0.362 |
|
| 2021 |
Alanazi A, Ivanov A, Kumari N, Lin X, Wang S, Kovalskyy D, Nekhai S. Targeting Tat-TAR RNA Interaction for HIV-1 Inhibition. Viruses. 13. PMID 34696435 DOI: 10.3390/v13102004 |
0.347 |
|
| 2021 |
Kumari N, Nouraie SM, Ahmad A, Lassiter H, Khan JI, Diaz SF, Afangbedji N, Wang S, Houston PE, Ammosova T, de Mulder Rougvie M, Rana S, Nixon D, Anastos K, Lazar J, ... ... Nekhai S, et al. Restriction of HIV-1 Infection in Sickle Cell Trait. Blood Advances. PMID 34496009 DOI: 10.1182/bloodadvances.2021004247 |
0.44 |
|
| 2020 |
Lin X, Sajith AM, Wang S, Kumari N, Choy MS, Ahmad A, Cadet DR, Gu X, Ivanov AI, Peti W, Kulkarni A, Nekhai S. Structural Optimization of 2,3-Dihydro-1H-cyclopenta[]quinolines Targeting the Noncatalytic RVxF Site of Protein Phosphatase 1 for HIV-1 Inhibition. Acs Infectious Diseases. PMID 33258581 DOI: 10.1021/acsinfecdis.0c00511 |
0.434 |
|
| 2020 |
Zhang X, Song J, Shah BN, Nekhai S, Miasnikova G, Sergueeva A, Prchal JT, Gordeuk VR. Peripheral blood mononuclear cells show prominent gene expression by erythroid progenitors in diseases characterized by heightened erythropoiesis. British Journal of Haematology. PMID 32399971 DOI: 10.1111/Bjh.16696 |
0.309 |
|
| 2020 |
Jerebtsova M, Ahmad A, Kumari N, Rutagarama O, Nekhai S. Macrophage HIV-1 Gene Expression and Delay Resolution of Inflammation in HIV-Tg Mice. Viruses. 12. PMID 32121564 DOI: 10.3390/V12030277 |
0.474 |
|
| 2020 |
Jerebtsova M, Ahmad A, Niu X, Rutagarama O, Nekhai S. HIV-1 Transcription Inhibitor 1E7-03 Restores LPS-Induced Alteration of Lung Leukocytes' Infiltration Dynamics and Resolves Inflammation in HIV Transgenic Mice. Viruses. 12. PMID 32059509 DOI: 10.3390/V12020204 |
0.478 |
|
| 2020 |
Kumari N, Jerebtsova M, Wang S, Diaz S, Nekhai S. Interferon Induction By HbS, SERINC5 Upregulation and Reduction of HIV-1 Nef and AP2 Contribute to HIV-1 Restriction in Sickle Cell Disease Blood. 136: 5-6. DOI: 10.1182/blood-2020-142699 |
0.449 |
|
| 2019 |
Younan P, Santos RI, Ramanathan P, Iampietro M, Nishida A, Dutta M, Ammosova T, Meyer M, Katze MG, Popov VL, Nekhai S, Bukreyev A. Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection. Plos Pathogens. 15: e1008068. PMID 31648236 DOI: 10.1371/Journal.Ppat.1008068 |
0.34 |
|
| 2019 |
Lin X, Ammosova T, Choy MS, Pietzsch CA, Ivanov A, Ahmad A, Saygideğer Y, Kumari N, Kovalskyy D, Üren A, Peti W, Bukreyev A, Nekhai S. Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition. Frontiers in Microbiology. 10: 2145. PMID 31572348 DOI: 10.3389/Fmicb.2019.02145 |
0.304 |
|
| 2019 |
Ivanov A, Ramanathan P, Parry C, Ilinykh PA, Lin X, Petukhov M, Obukhov Y, Ammosova T, Amarasinghe GK, Bukreyev A, Nekhai S. Global phosphoproteomic analysis of Ebola virions reveals a novel role for VP35 phosphorylation-dependent regulation of genome transcription. Cellular and Molecular Life Sciences : Cmls. PMID 31562565 DOI: 10.1007/S00018-019-03303-1 |
0.313 |
|
| 2019 |
Kumari N, Nouraie SM, Lassiter H, Ahmad A, Anastos K, Lazar J, Kassaye S, Aouizerat B, French A, Gange S, Adimora A, Weitzmann N, Fischl M, Kempf M, Nekhai S. Control of HIV-1 Infection By Ferroportin Q248H Mutation Blood. 134: 953-953. DOI: 10.1182/Blood-2019-128685 |
0.546 |
|
| 2018 |
Ammosova T, Pietzsch CA, Saygideger Y, Ilatovsky A, Lin X, Ivanov A, Kumari N, Jerebtsova M, Kulkarni A, Petukhov M, Üren A, Bukreyev A, Nekhai S. Protein Phosphatase 1-Targeting Small-Molecule C31 Inhibits Ebola Virus Replication. The Journal of Infectious Diseases. PMID 30169869 DOI: 10.1093/Infdis/Jiy422 |
0.322 |
|
| 2018 |
Tigabu B, Ramanathan P, Ivanov A, Lin X, Ilinykh PA, Parry CS, Freiberg AN, Nekhai S, Bukreyev A. PHOSPHORYLATED VP30 OF MARBURG VIRUS IS A REPRESSOR OF TRANSCRIPTION. Journal of Virology. PMID 30135121 DOI: 10.1128/Jvi.00426-18 |
0.316 |
|
| 2018 |
Ivanov A, Lin X, Ammosova T, Ilatovskiy AV, Kumari N, Lassiter H, Afangbedji N, Niu X, Petukhov MG, Nekhai S. HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription. Retrovirology. 15: 39. PMID 29792216 DOI: 10.1186/S12977-018-0422-5 |
0.516 |
|
| 2018 |
Carey BD, Ammosova T, Pinkham C, Lin X, Zhou W, Liotta LA, Nekhai S, Kehn-Hall K. Protein Phosphatase 1α Interacts with Venezuelan Equine Encephalitis Virus Capsid Protein and Regulates Viral Replication through Modulation of Capsid Phosphorylation. Journal of Virology. PMID 29769351 DOI: 10.1128/Jvi.02068-17 |
0.38 |
|
| 2018 |
Khaibullina A, Adjei EA, Afangbedji N, Ivanov A, Kumari N, Almeida LEF, Quezado ZMN, Nekhai S, Jerebtsova M. RON kinase inhibition reduces renal endothelial injury in sickle cell disease mice. Haematologica. PMID 29519868 DOI: 10.3324/Haematol.2017.180992 |
0.317 |
|
| 2018 |
Kumari N, de Mulder M, Khan J, Ahmad A, Wang S, Lassiter H, Smith N, Afangbedji NKA, Ivanov A, Shah M, Diaz S, Rana S, Nixon D, Nekhai S. Restriction of HIV-1 Infection in Sickle Cell Disease and Trait Blood. 132: 2337-2337. DOI: 10.1182/Blood-2018-99-117029 |
0.559 |
|
| 2017 |
Lin X, Kumari N, DeMarino C, Kont YS, Ammosova T, Kulkarni A, Jerebtsova M, Vazquez-Meves G, Ivanov A, Dmytro K, Üren A, Kashanchi F, Nekhai S. Inhibition of HIV-1 infection in humanized mice and metabolic stability of protein phosphatase-1-targeting small molecule 1E7-03. Oncotarget. 8: 76749-76769. PMID 29100346 DOI: 10.18632/Oncotarget.19999 |
0.487 |
|
| 2017 |
Lin X, Ammosova T, Kumari N, Nekhai S. Protein Phosphatase-1 -targeted Small Molecules, Iron Chelators and Curcumin Analogs as HIV-1 Antivirals. Current Pharmaceutical Design. PMID 28677499 DOI: 10.2174/1381612823666170704123620 |
0.567 |
|
| 2017 |
Kumari N, Mulder Md, Afangbedji NKA, Wang S, Diaz S, Nixon D, Nekhai S. Hemin and Iron Modulated Intrinsic Cellular Factors Regulate HIV-1 Replication in Sickle Cell Disease Blood. 130: 3492-3492. DOI: 10.1182/Blood.V130.Suppl_1.3492.3492 |
0.538 |
|
| 2016 |
Kumari N, Ammosova T, Diaz S, Lin X, Niu X, Ivanov A, Jerebtsova M, Dhawan S, Oneal P, Nekhai S. Increased iron export by ferroportin induces restriction of HIV-1 infection in sickle cell disease. Blood Advances. 1: 170-183. PMID 28203649 DOI: 10.1182/Bloodadvances.2016000745 |
0.593 |
|
| 2016 |
Zhang X, Shah BN, Zhang W, Saraf SL, Miasnikova G, Sergueeva A, Ammosova T, Niu X, Nouraie M, Nekhai S, Castro O, Gladwin MT, Prchal JT, Garcia JG, Machado RF, et al. A genetic variation associated with plasma erythropoietin and a non-coding transcript of PRKAR1A in sickle cell disease. Human Molecular Genetics. 25: 4601-4609. PMID 28173069 DOI: 10.1093/Hmg/Ddw299 |
0.334 |
|
| 2016 |
Ammosova T, Washington K, Rotimi J, Kumari N, Smith KA, Niu X, Jerebtsova M, Nekhai S. Protein Phosphatase-1 Regulates Expression of Neuregulin-1. Biology. 5. PMID 27918433 DOI: 10.3390/Biology5040049 |
0.637 |
|
| 2016 |
Pleet ML, Mathiesen A, DeMarino C, Akpamagbo YA, Barclay RA, Schwab A, Iordanskiy S, Sampey GC, Lepene B, Nekhai S, Aman MJ, Kashanchi F. Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction. Frontiers in Microbiology. 7: 1765. PMID 27872619 DOI: 10.3389/Fmicb.2016.01765 |
0.379 |
|
| 2016 |
Santos S, Obukhov Y, Nekhai S, Pushkarsky T, Brichacek B, Bukrinsky M, Iordanskiy S. Cellular minichromosome maintenance complex component 5 (MCM5) is incorporated into HIV-1 virions and modulates viral replication in the newly infected cells. Virology. 497: 11-22. PMID 27414250 DOI: 10.1016/J.Virol.2016.06.023 |
0.501 |
|
| 2016 |
Ogunwuyi O, Kumari N, Smith KA, Bolshakov O, Adesina S, Gugssa A, Anderson WA, Nekhai S, Akala EO. Antiretroviral Drugs-Loaded Nanoparticles Fabricated by Dispersion Polymerization with Potential for HIV/AIDS Treatment. Infectious Diseases. 9: 21-32. PMID 27013886 DOI: 10.4137/Idrt.S38108 |
0.695 |
|
| 2016 |
Baer A, Shafagati N, Benedict A, Ammosova T, Ivanov A, Hakami RM, Terasaki K, Makino S, Nekhai S, Kehn-Hall K. Protein Phosphatase-1 Regulates Rift Valley Fever Virus Replication. Antiviral Research. PMID 26801627 DOI: 10.1016/J.Antiviral.2016.01.007 |
0.318 |
|
| 2016 |
Afangbedji NKA, Kumari N, Kowalskyy D, Nekhai S. Effects of Phenyl-1-Pyridin-2yl-Ethanone (PPY)-Based Iron Chelators on the Formation of Methemoglobin Blood. 128: 4823-4823. DOI: 10.1182/Blood.V128.22.4823.4823 |
0.305 |
|
| 2016 |
Kumari N, Ammosova T, Diaz S, Lin X, Niu X, Ivanov A, Dhawan S, Oneal PA, Nekhai S. Increased Iron Export By Ferroportin Induces Restriction of HIV-1 Infection in Sickle Cell Disease By SAMHD1 Blood. 128: 201-201. DOI: 10.1182/Blood.V128.22.201.201 |
0.584 |
|
| 2016 |
Vazquez-Meves G, Kumari N, Afangbedji N, Khaibullina A, Quezado Z, Nekhai S, Jerebtsova M. Upregulation of Renal Iron Metabolism in Sickle Cell Disease Mice Blood. 128: 1276-1276. DOI: 10.1182/Blood.V128.22.1276.1276 |
0.338 |
|
| 2015 |
Smith KA, Lin X, Bolshakov O, Griffin J, Niu X, Kovalskyy D, Ivanov A, Jerebtsova M, Taylor RE, Akala E, Nekhai S. Activation of HIV-1 with Nanoparticle-Packaged Small-Molecule Protein Phosphatase-1-Targeting Compound. Scientia Pharmaceutica. 83: 535-48. PMID 26839837 DOI: 10.3797/Scipharm.1502-01 |
0.716 |
|
| 2015 |
Kumari N, Kulkarni AA, Lin X, McLean C, Ammosova T, Ivanov A, Hipolito M, Nekhai S, Nwulia E. Inhibition of HIV-1 by curcumin A, a novel curcumin analog. Drug Design, Development and Therapy. 9: 5051-60. PMID 26366056 DOI: 10.2147/Dddt.S86558 |
0.533 |
|
| 2015 |
Tyagi M, Iordanskiy S, Ammosova T, Kumari N, Smith K, Breuer D, Ilatovskiy AV, Kont YS, Ivanov A, Üren A, Kovalskyy D, Petukhov M, Kashanchi F, Nekhai S. Reactivation of latent HIV-1 provirus via targeting protein phosphatase-1. Retrovirology. 12: 63. PMID 26178009 DOI: 10.1186/S12977-015-0190-4 |
0.723 |
|
| 2015 |
van Beers EJ, Yang Y, Raghavachari N, Tian X, Allen DT, Nichols JS, Mendelsohn L, Nekhai S, Gordeuk VR, Taylor JG, Kato GJ. Iron, inflammation, and early death in adults with sickle cell disease. Circulation Research. 116: 298-306. PMID 25378535 DOI: 10.1161/Circresaha.116.304577 |
0.314 |
|
| 2015 |
Smith KA, Lin X, Bolshakov O, Griffin J, Niu X, Kovalskyy D, Ivanov A, Jerebtsova M, Taylor RE, Akala E, Nekhai S. Activation of HIV-1 with nanoparticle-packaged small-molecule protein phosphatase-1-targeting compound Scientia Pharmaceutica. 83: 535-548. DOI: 10.3797/scipharm.1502-01 |
0.618 |
|
| 2015 |
Zhang X, Zhang W, Shah B, Miasnikova G, Sergueeva A, Ammosova T, Niu X, Nouraie M, Nekhai S, Machado RF, Garcia JG, Gladwin MT, Castro OL, Gordeuk VR. Hydroxyurea Treatment Is Associated with Elevated Serum Erythropoietin Concentration but Suppressed Global Hypoxic Transcriptional Responses in Sickle Cell Disease Blood. 126: 3380-3380. DOI: 10.1182/Blood.V126.23.3380.3380 |
0.335 |
|
| 2015 |
Kumari N, Ammosova T, Nekhai S. Heme Oxygenase-1, Ferroportin and SAMHD1 Induction By Heme Inhibits HIV-1 Blood. 126: 3359-3359. DOI: 10.1182/Blood.V126.23.3359.3359 |
0.595 |
|
| 2014 |
Kumari N, Iordanskiy S, Kovalskyy D, Breuer D, Niu X, Lin X, Xu M, Gavrilenko K, Kashanchi F, Dhawan S, Nekhai S. Phenyl-1-Pyridin-2yl-ethanone-based iron chelators increase IκB-α expression, modulate CDK2 and CDK9 activities, and inhibit HIV-1 transcription. Antimicrobial Agents and Chemotherapy. 58: 6558-71. PMID 25155598 DOI: 10.1128/Aac.02918-14 |
0.572 |
|
| 2014 |
Ammosova T, Platonov M, Ivanov A, Kont YS, Kumari N, Kehn-Hall K, Jerebtsova M, Kulkarni AA, Uren A, Kovalskyy D, Nekhai S. 1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription. British Journal of Pharmacology. 171: 5059-75. PMID 25073485 DOI: 10.1111/Bph.12863 |
0.516 |
|
| 2014 |
Ilinykh PA, Tigabu B, Ivanov A, Ammosova T, Obukhov Y, Garron T, Kumari N, Kovalskyy D, Platonov MO, Naumchik VS, Freiberg AN, Nekhai S, Bukreyev A. Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription. The Journal of Biological Chemistry. 289: 22723-38. PMID 24936058 DOI: 10.1074/Jbc.M114.575050 |
0.367 |
|
| 2014 |
Nekhai S, Petukhov M, Breuer D. Regulation of CDK9 activity by phosphorylation and dephosphorylation. Biomed Research International. 2014: 964964. PMID 24524087 DOI: 10.1155/2014/964964 |
0.442 |
|
| 2014 |
Zhang X, Zhang W, Ma SF, Desai AA, Saraf S, Miasniakova G, Sergueeva A, Ammosova T, Xu M, Nekhai S, Abbasi T, Casanova NG, Steinberg MH, Baldwin CT, Sebastiani P, et al. Hypoxic response contributes to altered gene expression and precapillary pulmonary hypertension in patients with sickle cell disease. Circulation. 129: 1650-8. PMID 24515990 DOI: 10.1161/Circulationaha.113.005296 |
0.303 |
|
| 2014 |
Zhang X, Zhang W, Ma SF, Miasniakova G, Sergueeva A, Ammosova T, Xu M, Nekhai S, Nourai M, Wade MS, Prchal JT, Garcia JG, Machado RF, Gordeuk VR. Iron deficiency modifies gene expression variation induced by augmented hypoxia sensing. Blood Cells, Molecules & Diseases. 52: 35-45. PMID 23993337 DOI: 10.1182/Blood.V120.21.1765.1765 |
0.377 |
|
| 2013 |
Nekhai S, Kumari N, Dhawan S. Role of cellular iron and oxygen in the regulation of HIV-1 infection. Future Virology. 8: 301-311. PMID 23678366 DOI: 10.2217/Fvl.13.6 |
0.563 |
|
| 2013 |
Zhou ZH, Kumari N, Nekhai S, Clouse KA, Wahl LM, Yamada KM, Dhawan S. Heme oxygenase-1 induction alters chemokine regulation and ameliorates human immunodeficiency virus-type-1 infection in lipopolysaccharide-stimulated macrophages. Biochemical and Biophysical Research Communications. 435: 373-7. PMID 23665328 DOI: 10.1016/J.Bbrc.2013.04.095 |
0.443 |
|
| 2013 |
Van Duyne R, Guendel I, Jaworski E, Sampey G, Klase Z, Chen H, Zeng C, Kovalskyy D, El Kouni MH, Lepene B, Patanarut A, Nekhai S, Price DH, Kashanchi F. Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription. Journal of Molecular Biology. 425: 812-29. PMID 23247501 DOI: 10.1016/J.Jmb.2012.12.005 |
0.476 |
|
| 2013 |
Nekhai S, Xu M, Foster A, Kasvosve I, Diaz S, Machado RF, Castro OL, Kato GJ, Taylor JG, Gordeuk VR. Reduced sensitivity of the ferroportin Q248H mutant to physiological concentrations of hepcidin. Haematologica. 98: 455-63. PMID 23065513 DOI: 10.3324/Haematol.2012.066530 |
0.773 |
|
| 2013 |
Kumari N, Kovalsky D, Breuer D, Niu X, Nekhai S. Iron depletion by iron chelators or ferroportin inhibits HIV-1 through the induction of HIF1α, p21 and IKBα and the inhibition of CDK9 and CDK2 Retrovirology. 10: 63. DOI: 10.1186/1742-4690-10-S1-P63 |
0.55 |
|
| 2013 |
Nekhai SA, Kumari N, Breuer D, Mclean C, Ammosova T, Dhawan S. Induction Of Ferroportin, Erg-1, p21 and IKBα In Sickle Cell Disease May Contribute To HIV-1 Inhibition Blood. 122: 2250-2250. DOI: 10.1182/Blood.V122.21.2250.2250 |
0.511 |
|
| 2013 |
Kumari N, Nekhai SA. Heme and Iron Chelators Inhibit HIV-1 Through The Induction Of Heme Oxygenase 1, Ferroportin and IKBα Blood. 122: 2198-2198. DOI: 10.1182/BLOOD.V122.21.2198.2198 |
0.514 |
|
| 2012 |
Breuer D, Kotelkin A, Ammosova T, Kumari N, Ivanov A, Ilatovskiy AV, Beullens M, Roane PR, Bollen M, Petukhov MG, Kashanchi F, Nekhai S. CDK2 regulates HIV-1 transcription by phosphorylation of CDK9 on serine 90. Retrovirology. 9: 94. PMID 23140174 DOI: 10.1186/1742-4690-9-94 |
0.516 |
|
| 2012 |
Jerebtsova M, Kumari N, Xu M, de Melo GB, Niu X, Jeang KT, Nekhai S. HIV-1 Resistant CDK2-Knockdown Macrophage-Like Cells Generated from 293T Cell-Derived Human Induced Pluripotent Stem Cells. Biology. 1: 175-195. PMID 22934150 DOI: 10.3390/Biology1020175 |
0.464 |
|
| 2012 |
Jerebtsova M, Kumari N, Obuhkov Y, Nekhai S. Adenoviral E4 gene stimulates secretion of pigmental epithelium derived factor (PEDF) that maintains long-term survival of human glomerulus-derived endothelial cells. Molecular & Cellular Proteomics : McP. 11: 1378-88. PMID 22915824 DOI: 10.1074/Mcp.M112.020313 |
0.304 |
|
| 2012 |
Santos S, Obukhov Y, Nekhai S, Bukrinsky M, Iordanskiy S. Virus-producing cells determine the host protein profiles of HIV-1 virion cores. Retrovirology. 9: 65. PMID 22889230 DOI: 10.1186/1742-4690-9-65 |
0.459 |
|
| 2012 |
Narayanan A, Sampey G, Van Duyne R, Guendel I, Kehn-Hall K, Roman J, Currer R, Galons H, Oumata N, Joseph B, Meijer L, Caputi M, Nekhai S, Kashanchi F. Use of ATP analogs to inhibit HIV-1 transcription. Virology. 432: 219-31. PMID 22771113 DOI: 10.1016/J.Virol.2012.06.007 |
0.465 |
|
| 2012 |
Ammosova T, Platonov M, Yedavalli VR, Obukhov Y, Gordeuk VR, Jeang KT, Kovalskyy D, Nekhai S. Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1. Plos One. 7: e39481. PMID 22768081 DOI: 10.1371/Journal.Pone.0039481 |
0.528 |
|
| 2012 |
Nouraie M, Nekhai S, Gordeuk VR. Sickle cell disease is associated with decreased HIV but higher HBV and HCV comorbidities in U.S. hospital discharge records: a cross-sectional study. Sexually Transmitted Infections. 88: 528-33. PMID 22628662 DOI: 10.1136/Sextrans-2011-050459 |
0.464 |
|
| 2012 |
Nekhai S, Kumari N, Xu M, Foster A, Diaz S, Gordeuk VR. Ferroportin Q248H Mutation Protects From HIV-1 Infection in Vitro Blood. 120: 993-993. DOI: 10.1182/Blood.V120.21.993.993 |
0.829 |
|
| 2012 |
Gordeuk VR, Zhang X, Zhang W, Ma S, Miasniakova G, Sergueeva A, Ammosova T, Xu M, Nekhai S, Prchal JT, Wade M, Garcia JG, Machado R. The Hypoxic Response and Altered Gene Expression in Patients with Sickle Cell Disease Blood. 120: 3245-3245. DOI: 10.1182/Blood.V120.21.3245.3245 |
0.34 |
|
| 2012 |
Kumari N, Xu M, Kovlaskyy D, Dhawan S, Nekhai S. Novel 2-Phenyl-1-Pyridin-2yl-Ethanone (PpY) Based Iron Chelators Increase Expression of IkBα and Heme Oxygenase-1 and Inhibit HIV-1 Blood. 120: 1052-1052. DOI: 10.1182/Blood.V120.21.1052.1052 |
0.572 |
|
| 2011 |
Gordeuk VR, Miasnikova GY, Sergueeva AI, Niu X, Nouraie M, Okhotin DJ, Polyakova LA, Ammosova T, Nekhai S, Ganz T, Prchal JT. Chuvash polycythemia VHLR200W mutation is associated with down-regulation of hepcidin expression. Blood. 118: 5278-82. PMID 21876117 DOI: 10.1182/Blood-2011-03-345512 |
0.346 |
|
| 2011 |
Van Duyne R, Guendel I, Narayanan A, Gregg E, Shafagati N, Tyagi M, Easley R, Klase Z, Nekhai S, Kehn-Hall K, Kashanchi F. Varying modulation of HIV-1 LTR activity by Baf complexes. Journal of Molecular Biology. 411: 581-96. PMID 21699904 DOI: 10.1016/J.Jmb.2011.06.001 |
0.53 |
|
| 2011 |
Ammosova T, Obukhov Y, Kotelkin A, Breuer D, Beullens M, Gordeuk VR, Bollen M, Nekhai S. Protein phosphatase-1 activates CDK9 by dephosphorylating Ser175. Plos One. 6: e18985. PMID 21533037 DOI: 10.1371/Journal.Pone.0018985 |
0.421 |
|
| 2011 |
Ammosova T, Yedavalli VR, Niu X, Jerebtsova M, Van Eynde A, Beullens M, Bollen M, Jeang KT, Nekhai S. Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription. The Journal of Biological Chemistry. 286: 3798-804. PMID 21098020 DOI: 10.1074/Jbc.M110.196493 |
0.555 |
|
| 2011 |
Debebe Z, Ammosova T, Breuer D, Lovejoy DB, Kalinowski DS, Kumar K, Jerebtsova M, Ray P, Kashanchi F, Gordeuk VR, Richardson DR, Nekhai S. Iron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9. Molecular Pharmacology. 79: 185-96. PMID 20956357 DOI: 10.1124/Mol.110.069062 |
0.566 |
|
| 2011 |
Jerebtsova M, Klotchenko SA, Artamonova TO, Ammosova T, Washington K, Egorov VV, Shaldzhyan AA, Sergeeva MV, Zatulovskiy EA, Temkina OA, Petukhov MG, Vasin AV, Khodorkovskii MA, Orlov YN, Nekhai S. Mass spectrometry and biochemical analysis of RNA polymerase II: targeting by protein phosphatase-1. Molecular and Cellular Biochemistry. 347: 79-87. PMID 20941529 DOI: 10.1007/S11010-010-0614-3 |
0.332 |
|
| 2011 |
Van Duyne R, Guendel I, Shafagati N, Kehn-Hall K, Easley R, Klase Z, Nekhai S, Tyagi M, Kashanchi F. Varying modulation of HTLV-1 LTR activity by BAF complexes Retrovirology. 8: A180. DOI: 10.1186/1742-4690-8-S1-A180 |
0.315 |
|
| 2011 |
Debebe Z, Ammosova T, Breuer D, Lovejoy DB, Kalinowski DS, Kumar K, Jerebtsova M, Ray P, Kashanchi F, Gordeuk VR, Richardson DR, Nekhai S. Iron chelators of the Di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: Identification of novel cellular targets-iron, cyclin-dependent kinase (CDK) 2, and CDK9 (Molecular Pharmacology (2011) 79 (185-196)) Molecular Pharmacology. 80. DOI: 10.1124/Mol.80.6.1190 |
0.479 |
|
| 2010 |
Xu M, Kashanchi F, Foster A, Rotimi J, Turner W, Gordeuk VR, Nekhai S. Hepcidin induces HIV-1 transcription inhibited by ferroportin. Retrovirology. 7: 104. PMID 21126372 DOI: 10.1186/1742-4690-7-104 |
0.815 |
|
| 2010 |
Kasvosve I, Debebe Z, Nekhai S, Gordeuk VR. Ferroportin (SLC40A1) Q248H mutation is associated with lower circulating plasma tumor necrosis factor-alpha and macrophage migration inhibitory factor concentrations in African children. Clinica Chimica Acta; International Journal of Clinical Chemistry. 411: 1248-52. PMID 20460119 DOI: 10.1016/J.Cca.2010.04.031 |
0.334 |
|
| 2010 |
Ammosova T, Charles S, Foster A, Diaz S, Kim B, Gordeuk VR, Nekhai S. Inhibition of HIV-1 in sickle cell disease peripheral blood mononuclear cells F1000research. 1. DOI: 10.7490/F1000Research.154.1 |
0.803 |
|
| 2010 |
Xu M, Foster A, Diaz S, Nekhai S, Gordeuk VR. Reduced sensitivity of the ferroportin Q248H mutant to low concentrations of hepcidin F1000research. 1. DOI: 10.7490/F1000Research.132.1 |
0.736 |
|
| 2009 |
Charles S, Ammosova T, Cardenas J, Foster A, Rotimi J, Jerebtsova M, Ayodeji AA, Niu X, Ray PE, Gordeuk VR, Kashanchi F, Nekhai S. Regulation of HIV-1 transcription at 3% versus 21% oxygen concentration. Journal of Cellular Physiology. 221: 469-79. PMID 19626680 DOI: 10.1002/Jcp.21882 |
0.806 |
|
| 2009 |
Hairston J, Combi K, Foster A, Kim B, Gordeuk VR, Nekhai S. Non-Competitive Protein Phosphatase-1 Inhibitors Prevent Sickling of SS RBCs. Blood. 114: 4038-4038. DOI: 10.1182/Blood.V114.22.4038.4038 |
0.786 |
|
| 2009 |
Xu M, Foster A, Diaz S, Nekhai S, Gordeuk VR. Reduced Sensitivity of the Ferroportin Q248H Mutant to Low Concentrations of Hepcidin. Blood. 114: 2002-2002. DOI: 10.1182/Blood.V114.22.2002.2002 |
0.767 |
|
| 2009 |
Ammosova T, Charles S, Rotimi J, Foster A, Diaz S, Kim B, Gordeuk VR, Nekhai S. Inhibition of HIV-1 in Sickle Cell Disease Peripheral Blood Mononuclear Cells. Blood. 114: 1509-1509. DOI: 10.1182/Blood.V114.22.1509.1509 |
0.822 |
|
| 2008 |
Gordeuk VR, Diaz SF, Onojobi GO, Kasvosve I, Debebe Z, Edossa A, Pantin JM, Xiong S, Nekhai S, Nouraie M, Tsukamoto H, Taylor RE. Ferroportin Q248h, dietary iron, and serum ferritin in community African-Americans with low to high alcohol consumption. Alcoholism, Clinical and Experimental Research. 32: 1947-53. PMID 18782341 DOI: 10.1111/J.1530-0277.2008.00782.X |
0.302 |
|
| 2008 |
Berro R, Pedati C, Kehn-Hall K, Wu W, Klase Z, Even Y, Genevière AM, Ammosova T, Nekhai S, Kashanchi F. CDK13, a new potential human immunodeficiency virus type 1 inhibitory factor regulating viral mRNA splicing. Journal of Virology. 82: 7155-66. PMID 18480452 DOI: 10.1128/Jvi.02543-07 |
0.471 |
|
| 2008 |
Debebe Z, Kumar K, Ammosova T, Niu X, Richardson DR, Gordeuk VR, Nekhai S. Inhibition of HIV-1 by DpT-Based Iron Chelators Blood. 112: 79-79. DOI: 10.1182/Blood.V112.11.79.79 |
0.584 |
|
| 2008 |
Niu X, Miasnikova GY, Sergueeva AI, Okhotin DJ, Nouraie M, Ammosova T, Nekhai S, Gordeuk VR. Altered Immune Responses in Patients with Chuvash Polycythemia Blood. 112: 4582-4582. DOI: 10.1182/Blood.V112.11.4582.4582 |
0.313 |
|
| 2008 |
Niu X, Nouraie M, Minniti C, Sable C, Campbell A, Rana SR, Kato GJ, Gladwin M, Castro O, Ammosova T, Nekhai S, Gordeuk VR. Correlations Between Cytokines and Elevated Tricuspid Regurgitant Jet Velocity in Children and Adolescents with Sickle Cell Disease Blood. 112: 2484-2484. DOI: 10.1182/Blood.V112.11.2484.2484 |
0.314 |
|
| 2008 |
Nekhai S, Foster A, Xu M, Niu X, Rotimi J, Gordeuk VR. Inhibition of HIV-1 by Ferroprotin Expression. Blood. 112: 1464-1464. DOI: 10.1182/Blood.V112.11.1464.1464 |
0.829 |
|
| 2007 |
Debebe Z, Ammosova T, Jerebtsova M, Kurantsin-Mills J, Niu X, Charles S, Richardson DR, Ray PE, Gordeuk VR, Nekhai S. Iron chelators ICL670 and 311 inhibit HIV-1 transcription. Virology. 367: 324-33. PMID 17631934 DOI: 10.1016/J.Virol.2007.06.011 |
0.592 |
|
| 2007 |
Nekhai S, Jerebtsova M, Jackson A, Southerland W. Regulation of HIV-1 transcription by protein phosphatase 1. Current Hiv Research. 5: 3-9. PMID 17266553 DOI: 10.2174/157016207779316279 |
0.533 |
|
| 2007 |
Berro R, de la Fuente C, Klase Z, Kehn K, Parvin L, Pumfery A, Agbottah E, Vertes A, Nekhai S, Kashanchi F. Identifying the membrane proteome of HIV-1 latently infected cells. The Journal of Biological Chemistry. 282: 8207-18. PMID 17237230 DOI: 10.1074/Jbc.M606324200 |
0.464 |
|
| 2007 |
Nekhai S, Bhat UG, Ammosova T, Radhakrishnan SK, Jerebtsova M, Niu X, Foster A, Layden TJ, Gartel AL. A novel anticancer agent ARC antagonizes HIV-1 and HCV Oncogene. 26: 3899-3903. PMID 17173067 DOI: 10.1038/Sj.Onc.1210158 |
0.78 |
|
| 2007 |
Ammosova T, Xu M, Nekhai S, Kato GJ, Gladwin MT, Castro OL, Gordeuk VR. Detection of the mRNA Transcription Level of Several Genes of the HIF and NO Metabolic Pathways in PBMCs of Sickle Cell Disease Patients Using Quantitative RT-PCR Assay. Blood. 110: 844-844. DOI: 10.1182/Blood.V110.11.844.844 |
0.306 |
|
| 2007 |
Debebe Z, Ammosova T, Nick H, Niu X, Jerebtsova M, Ray P, Gordeuk VR, Nekhai S. Iron Chelator ICL670 Inhibits HIV-1 Transcription. Blood. 110: 3863-3863. DOI: 10.1182/Blood.V110.11.3863.3863 |
0.59 |
|
| 2007 |
Edossa A, Gordeuk VR, Nekhai S. Inhibition of HIV-1 Tat-Induced Interleukin-10 Expression by Mononuclear Cells at 3% O2. Blood. 110: 2282-2282. DOI: 10.1182/Blood.V110.11.2282.2282 |
0.445 |
|
| 2007 |
Nekhai S, Charles S, Ammosova T, Cardenas J, Jerebtsova M, Ayodeji AA, Niu X, Ray PE, Kashanchi F, Gordeuk VR. Oxygen Levels and HIV-1 Transcription. Blood. 110: 2280-2280. DOI: 10.1182/Blood.V110.11.2280.2280 |
0.591 |
|
| 2006 |
Nekhai S, Jeang KT. Transcriptional and post-transcriptional regulation of HIV-1 gene expression: role of cellular factors for Tat and Rev. Future Microbiology. 1: 417-26. PMID 17661632 DOI: 10.2217/17460913.1.4.417 |
0.532 |
|
| 2006 |
Ammosova T, Berro R, Jerebtsova M, Jackson A, Charles S, Klase Z, Southerland W, Gordeuk VR, Kashanchi F, Nekhai S. Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription. Retrovirology. 3: 78. PMID 17083724 DOI: 10.1186/1742-4690-3-78 |
0.545 |
|
| 2006 |
Epie N, Ammosova T, Turner W, Nekhai S. Inhibition of PP2A by LIS1 increases HIV-1 gene expression. Retrovirology. 3: 65. PMID 17018134 DOI: 10.1186/1742-4690-3-65 |
0.525 |
|
| 2006 |
Pumfery A, de la Fuente C, Berro R, Nekhai S, Kashanchi F, Chao SH. Potential use of pharmacological cyclin-dependent kinase inhibitors as anti-HIV therapeutics. Current Pharmaceutical Design. 12: 1949-61. PMID 16787240 DOI: 10.2174/138161206777442083 |
0.499 |
|
| 2006 |
Nekhai S, Jerebtsova M. Therapies for HIV with RNAi. Current Opinion in Molecular Therapeutics. 8: 52-61. PMID 16506526 |
0.335 |
|
| 2006 |
Ammosova T, Debebe Z, Niu X, Richardson DR, Jerebtsova M, Ray P, Gordeuk VR, Nekhai S. Iron Chelation, Cell Cycle-Dependent Kinases and HIV-1 Transcription. Blood. 108: 1550-1550. DOI: 10.1182/Blood.V108.11.1550.1550 |
0.596 |
|
| 2006 |
Nekhai S, Sharroya C, Ammosova T, Nui X, Jerebtsova M, Gordeuk VR. Hypoxia Inhibits HIV-1 Transcription. Blood. 108: 1305-1305. DOI: 10.1182/Blood.V108.11.1305.1305 |
0.565 |
|
| 2005 |
Ammosova T, Jerebtsova M, Beullens M, Lesage B, Jackson A, Kashanchi F, Southerland W, Gordeuk VR, Bollen M, Nekhai S. Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein. The Journal of Biological Chemistry. 280: 36364-71. PMID 16131488 DOI: 10.1074/Jbc.M503673200 |
0.53 |
|
| 2005 |
Ammosova T, Berro R, Kashanchi F, Nekhai S. RNA interference directed to CDK2 inhibits HIV-1 transcription. Virology. 341: 171-8. PMID 16085226 DOI: 10.1016/J.Virol.2005.06.041 |
0.536 |
|
| 2005 |
Ammosova T, Washington K, Debebe Z, Brady J, Nekhai S. Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription. Retrovirology. 2: 47. PMID 16048649 DOI: 10.1186/1742-4690-2-47 |
0.526 |
|
| 2005 |
Epie N, Ammosova T, Sapir T, Voloshin Y, Lane WS, Turner W, Reiner O, Nekhai S. HIV-1 Tat interacts with LIS1 protein. Retrovirology. 2: 6. PMID 15698475 DOI: 10.1186/1742-4690-2-6 |
0.472 |
|
| 2003 |
Ammosova T, Jerebtsova M, Beullens M, Voloshin Y, Ray PE, Kumar A, Bollen M, Nekhai S. Nuclear protein phosphatase-1 regulates HIV-1 transcription. The Journal of Biological Chemistry. 278: 32189-94. PMID 12788939 DOI: 10.1074/Jbc.M300521200 |
0.57 |
|
| 2002 |
Washington K, Ammosova T, Beullens M, Jerebtsova M, Kumar A, Bollen M, Nekhai S. Protein phosphatase-1 dephosphorylates the C-terminal domain of RNA polymerase-II. The Journal of Biological Chemistry. 277: 40442-8. PMID 12185079 DOI: 10.1074/Jbc.M205687200 |
0.37 |
|
| 2002 |
Deng L, Ammosova T, Pumfery A, Kashanchi F, Nekhai S. HIV-1 Tat interaction with RNA polymerase II C-terminal domain (CTD) and a dynamic association with CDK2 induce CTD phosphorylation and transcription from HIV-1 promoter. The Journal of Biological Chemistry. 277: 33922-9. PMID 12114499 DOI: 10.1074/Jbc.M111349200 |
0.479 |
|
| 2002 |
Nekhai S, Zhou M, Fernandez A, Lane WS, Lamb NJ, Brady J, Kumar A. HIV-1 Tat-associated RNA polymerase C-terminal domain kinase, CDK2, phosphorylates CDK7 and stimulates Tat-mediated transcription. The Biochemical Journal. 364: 649-57. PMID 12049628 DOI: 10.1042/Bj20011191 |
0.487 |
|
| 2002 |
Bharucha DC, Zhou M, Nekhai S, Brady JN, Shukla RR, Kumar A. A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat. Virology. 296: 6-16. PMID 12036313 DOI: 10.1006/Viro.2002.1438 |
0.496 |
|
| 2001 |
Zhou M, Nekhai S, Bharucha DC, Kumar A, Ge H, Price DH, Egly JM, Brady JN. TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription. The Journal of Biological Chemistry. 276: 44633-40. PMID 11572868 DOI: 10.1074/Jbc.M107466200 |
0.418 |
|
| 2000 |
Nekhai S, Bottaro DP, Woldehawariat G, Spellerberg A, Petryshyn R. A cell-permeable peptide inhibits activation of PKR and enhances cell proliferation. Peptides. 21: 1449-1456. PMID 11068090 DOI: 10.1016/S0196-9781(00)00297-7 |
0.313 |
|
| 2000 |
Nekhai S, Shukla RR, Fernandez A, Kumar A, Lamb NJ. Cell cycle-dependent stimulation of the HIV-1 promoter by Tat-associated CAK activator. Virology. 266: 246-56. PMID 10639311 DOI: 10.1006/Viro.1999.0035 |
0.499 |
|
| 1999 |
Woldehawariat G, Nekhai S, Petryshyn R. Differential phosphorylation of PKR associates with deregulation of eIF-2alpha phosphorylation and altered growth characteristics in 3T3-F442A fibroblasts. Molecular and Cellular Biochemistry. 198: 7-17. PMID 10497873 DOI: 10.1023/A:1006978622240 |
0.337 |
|
| 1999 |
Kaucic K, Nekhai S, Spellerberg A, Petryshyn RA. Growth Regulation in Hematopoietic Cells Is Partially Mediated by Double Stranded RNA-Dependent Protein Kinase Pediatric Research. 45: 148-148. DOI: 10.1203/00006450-199904020-00879 |
0.304 |
|
| 1997 |
Nekhai S, Shukla RR, Kumar A. A human primary T-lymphocyte-derived human immunodeficiency virus type 1 Tat-associated kinase phosphorylates the C-terminal domain of RNA polymerase II and induces CAK activity. Journal of Virology. 71: 7436-41. PMID 9311822 DOI: 10.1128/Jvi.71.10.7436-7441.1997 |
0.371 |
|
| 1996 |
Nekhai S, Kumar A, Bottaro DP, Petryshyn R. Peptides Derived from the Interferon-Induced PKR Prevent Activation by HIV-1 TAR RNA Virology. 222: 193-200. PMID 8806499 DOI: 10.1006/Viro.1996.0410 |
0.323 |
|
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