Joan Massague - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Oncology, Cell Biology, Biostatistics Biology

245 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, Campbell K, Cano A, Casanova J, Christofori G, Dedhar S, Derynck R, Ford HL, Fuxe J, García de Herreros A, et al. Author Correction: Guidelines and definitions for research on epithelial-mesenchymal transition. Nature Reviews. Molecular Cell Biology. PMID 34654908 DOI: 10.1038/s41580-021-00428-9  0.368
2020 Valiente M, Van Swearingen AED, Anders CK, Bairoch A, Boire A, Bos PD, Cittelly DM, Erez N, Ferraro GB, Fukumura D, Gril B, Herlyn M, Holmen SL, Jain RK, Joyce JA, ... ... Massague J, et al. Brain Metastasis Cell Lines Panel: a public resource of organotropic cell lines. Cancer Research. PMID 32641416 DOI: 10.1158/0008-5472.Can-20-0291  0.681
2020 Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, Campbell K, Cano A, Casanova J, Christofori G, Dedhar S, Derynck R, Ford HL, Fuxe J, García de Herreros A, et al. Guidelines and definitions for research on epithelial-mesenchymal transition. Nature Reviews. Molecular Cell Biology. PMID 32300252 DOI: 10.1038/S41580-020-0237-9  0.492
2020 Laughney AM, Hu J, Campbell NR, Bakhoum SF, Setty M, Lavallée VP, Xie Y, Masilionis I, Carr AJ, Kottapalli S, Allaj V, Mattar M, Rekhtman N, Xavier JB, Mazutis L, et al. Regenerative lineages and immune-mediated pruning in lung cancer metastasis. Nature Medicine. PMID 32042191 DOI: 10.1038/S41591-019-0750-6  0.331
2020 Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, Zhou Y, Liu L, Vanharanta S, Graves EE, Rankin EB, Curtis C, Massague J, Rabinowitz JD, Thompson CB, et al. Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Molecular Cancer Research : McR. PMID 31941752 DOI: 10.1158/1541-7786.Mcr-19-0606  0.324
2020 Su J, Morgani SM, David CJ, Wang Q, Er EE, Huang YH, Basnet H, Zou Y, Shu W, Soni RK, Hendrickson RC, Hadjantonakis AK, Massagué J. TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1. Nature. PMID 31915377 DOI: 10.1038/S41586-019-1897-5  0.399
2020 Ganesh K, Basnet H, Kaygusuz Y, Laughney A, He L, Sharma R, O'Rourke K, Reuter V, Huang Y, Masilionis I, Turkekul M, Er E, Manova-Todorova K, Saltz L, Weiser M, ... ... Massague J, et al. Abstract A12: L1CAM defines the regenerative origin of metastasis initiating cells in colorectal cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-A12  0.36
2020 Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, Zhou Y, Liu L, Vanharanta S, Graves EE, Rankin EB, Curtis C, Massague J, Rabinowitz JD, Thompson CB, et al. Abstract 5713: Reprogramming of serine metabolism during breast cancer progression Cancer Research. 80: 5713-5713. DOI: 10.1158/1538-7445.Am2020-5713  0.365
2019 Aragón E, Wang Q, Zou Y, Morgani SM, Ruiz L, Kaczmarska Z, Su J, Torner C, Tian L, Hu J, Shu W, Agrawal S, Gomes T, Márquez JA, Hadjantonakis AK, et al. Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-β signaling. Genes & Development. PMID 31582430 DOI: 10.1101/Gad.330837.119  0.414
2019 Huang YH, Hu J, Chen F, Lecomte N, Basnet H, David CJ, Witkin MD, Allen PJ, Leach SD, Hollmann TJ, Iacobuzio-Donahue CA, Massague J. ID1 mediates escape from TGF-β tumor suppression in pancreatic cancer. Cancer Discovery. PMID 31582374 DOI: 10.1158/2159-8290.Cd-19-0529  0.396
2019 Luo M, Bai J, Liu B, Yan P, Zuo F, Sun H, Sun Y, Xu X, Song Z, Yang Y, Massagué J, Lan X, Lu Z, Chen YG, Deng H, et al. H3K18ac Primes Mesendodermal Differentiation upon Nodal Signaling. Stem Cell Reports. PMID 31564646 DOI: 10.1016/J.Stemcr.2019.08.016  0.385
2019 Batlle E, Massagué J. Transforming Growth Factor-β Signaling in Immunity and Cancer. Immunity. 50: 924-940. PMID 30995507 DOI: 10.1016/J.Immuni.2019.03.024  0.373
2018 Er EE, Valiente M, Ganesh K, Zou Y, Agrawal S, Hu J, Griscom B, Rosenblum M, Boire A, Brogi E, Giancotti FG, Schachner M, Malladi S, Massagué J. Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization. Nature Cell Biology. PMID 30038252 DOI: 10.1038/S41556-018-0138-8  0.396
2018 Ganesh K, Massagué J. TGF-β Inhibition and Immunotherapy: Checkmate. Immunity. 48: 626-628. PMID 29669246 DOI: 10.1016/J.Immuni.2018.03.037  0.323
2018 David CJ, Massagué J. Contextual determinants of TGFβ action in development, immunity and cancer. Nature Reviews. Molecular Cell Biology. PMID 29643418 DOI: 10.1038/S41580-018-0007-0  0.41
2018 Xie XP, Laks DR, Sun D, Poran A, Laughney AM, Belenguer G, Massague J, Zhou X, Farinas I, Elemento O, Parada LF. Abstract 3015: Precise investigation of cancer stem cells in mouse glioblastoma Cancer Research. 78: 3015-3015. DOI: 10.1158/1538-7445.Am2018-3015  0.325
2017 Martin-Malpartida P, Batet M, Kaczmarska Z, Freier R, Gomes T, Aragón E, Zou Y, Wang Q, Xi Q, Ruiz L, Vea A, Márquez JA, Massagué J, Macias MJ. Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nature Communications. 8: 2070. PMID 29234012 DOI: 10.1038/S41467-017-02054-6  0.389
2017 Boire A, Zou Y, Shieh J, Macalinao DG, Pentsova E, Massagué J. Complement Component 3 Adapts the Cerebrospinal Fluid for Leptomeningeal Metastasis. Cell. 168: 1101-1113.e13. PMID 28283064 DOI: 10.1016/J.Cell.2017.02.025  0.358
2016 Wang Q, Zou Y, Nowotschin S, Kim SY, Li QV, Soh CL, Su J, Zhang C, Shu W, Xi Q, Huangfu D, Hadjantonakis AK, Massagué J. The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells. Cell Stem Cell. PMID 27889317 DOI: 10.1016/J.Stem.2016.10.002  0.33
2016 Chen Q, Boire A, Jin X, Valiente M, Er EE, Lopez-Soto A, Jacob LS, Patwa R, Shah H, Xu K, Cross JR, Massagué J. Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer. Nature. 533: 493-8. PMID 27225120 DOI: 10.1038/Nature18268  0.316
2016 Malladi S, Macalinao DG, Jin X, He L, Basnet H, Zou Y, de Stanchina E, Massagué J. Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT. Cell. 165: 45-60. PMID 27015306 DOI: 10.1016/J.Cell.2016.02.025  0.369
2016 David CJ, Huang YH, Chen M, Su J, Zou Y, Bardeesy N, Iacobuzio-Donahue CA, Massagué J. TGF-β Tumor Suppression through a Lethal EMT. Cell. PMID 26898331 DOI: 10.1016/J.Cell.2016.01.009  0.374
2016 Acharyya S, Massague J. Arresting supporters: targeting neutrophils in metastasis. Cell Research. 26: 273-4. PMID 26823207 DOI: 10.1038/Cr.2016.17  0.338
2016 Laughney AM, Malladi S, Macalinao D, Massagué J. Abstract A01: Investigating clonal heterogeneity and transcriptional vulnerabilities in latent metastasis Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-A01  0.35
2016 Malladi S, Macalinao DG, Jin X, He L, Massague J. Abstract PR06: Metastatic latency and immune evasion mediated by autocrine WNT inhibition Cancer Research. 76. DOI: 10.1158/1538-7445.Tummet15-Pr06  0.371
2016 Massagué J. Abstract IA18: Latency and immune evasion of metastatic stem cells Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-Ia18  0.377
2016 Massague J. Abstract SY20-03: Metastatic latency and immune evasion by cancer stem cells Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Sy20-03  0.371
2015 Obenauf AC, Massagué J. Surviving at a Distance: Organ-Specific Metastasis. Trends in Cancer. 1: 76-91. PMID 28741564 DOI: 10.1016/J.Trecan.2015.07.009  0.315
2015 Macias MJ, Martin-Malpartida P, Massagué J. Structural determinants of Smad function in TGF-β signaling. Trends in Biochemical Sciences. 40: 296-308. PMID 25935112 DOI: 10.1016/J.Tibs.2015.03.012  0.365
2015 Obenauf AC, Zou Y, Ji AL, Vanharanta S, Shu W, Shi H, Kong X, Bosenberg MC, Wiesner T, Rosen N, Lo RS, Massagué J. Therapy-induced tumour secretomes promote resistance and tumour progression. Nature. 520: 368-72. PMID 25807485 DOI: 10.1038/Nature14336  0.311
2015 Sevenich L, Bowman R, Mason S, Quail D, Rapaport F, Elie B, Brogi E, Brastianos P, Hahn W, Holsinger L, Massagué J, Leslie C, Joyce JA. Abstract IA18: A brain metastasis-promoting role for cathepsin S identified from analysis of tumor- and stroma-supplied proteolytic networks Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-Ia18  0.343
2015 Boire A, Zou Y, Jacob L, DeAngelis L, Massagué J. Bmet-03Solid Tumors Exploit Innate Immunity To Generate Leptomeningeal Metastases Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov208.03  0.356
2014 Vanharanta S, Marney CB, Shu W, Valiente M, Zou Y, Mele A, Darnell RB, Massagué J. Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer. Elife. 3. PMID 24898756 DOI: 10.7554/Elife.02734  0.345
2014 Oskarsson T, Batlle E, Massagué J. Metastatic stem cells: sources, niches, and vital pathways. Cell Stem Cell. 14: 306-21. PMID 24607405 DOI: 10.1016/J.Stem.2014.02.002  0.355
2014 Boire A, Zou Y, DeAngelis L, Massagué J. Bm-06Mechanistic Investigations Of Leptomeningeal Metastasis From Solid Tumors. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou240.6  0.33
2013 Stankic M, Pavlovic S, Chin Y, Brogi E, Padua D, Norton L, Massagué J, Benezra R. TGF-β-Id1 signaling opposes Twist1 and promotes metastatic colonization via a mesenchymal-to-epithelial transition. Cell Reports. 5: 1228-42. PMID 24332369 DOI: 10.1016/J.Celrep.2013.11.014  0.727
2013 Vanharanta S, Massagué J. Origins of metastatic traits. Cancer Cell. 24: 410-21. PMID 24135279 DOI: 10.1016/J.Ccr.2013.09.007  0.346
2013 Vanharanta S, Massagué J. Hypoxia signaling--license to metastasize. Cancer Discovery. 3: 1103-4. PMID 24124230 DOI: 10.1158/2159-8290.Cd-13-0481  0.324
2013 Zhang XH, Jin X, Malladi S, Zou Y, Wen YH, Brogi E, Smid M, Foekens JA, Massagué J. Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma. Cell. 154: 1060-73. PMID 23993096 DOI: 10.1016/J.Cell.2013.07.036  0.383
2013 Vanharanta S, Shu W, Brenet F, Hakimi AA, Heguy A, Viale A, Reuter VE, Hsieh JJ, Scandura JM, Massagué J. Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer. Nature Medicine. 19: 50-6. PMID 23223005 DOI: 10.1038/Nm.3029  0.376
2013 Massagué J. Abstract IA13: Niches and pathways of latent and overt metastasis Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-Ia13  0.408
2013 Zhang X, Jin X, Malladi S, Wen Y, Brogi E, Massague J. Abstract C8: Bone metastasis seed preselection by the primary tumor stroma Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-C8  0.345
2013 Valiente M, Lee DJ, Obenauf A, Huse JT, Chaft JE, Kris MG, Brogi E, Massagué J. Abstract A29: Cooption of the reactive stroma by brain metastasis relies on protease inhibitors Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A29  0.334
2013 Massagué J. Abstract IA25: Metastasis pathways Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-Ia25  0.4
2013 Acharyya S, Wojnarowicz P, Macalinao D, Khanin R, Granot Z, Benezra R, Massagué J. 1 Cytokine. 63: 243. DOI: 10.1016/J.Cyto.2013.06.004  0.381
2012 Calon A, Espinet E, Palomo-Ponce S, Tauriello DV, Iglesias M, Céspedes MV, Sevillano M, Nadal C, Jung P, Zhang XH, Byrom D, Riera A, Rossell D, Mangues R, Massagué J, et al. Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation. Cancer Cell. 22: 571-84. PMID 23153532 DOI: 10.1016/J.Ccr.2012.08.013  0.373
2012 Massagué J. TGFβ signalling in context. Nature Reviews. Molecular Cell Biology. 13: 616-30. PMID 22992590 DOI: 10.1038/Nrm3434  0.347
2012 Aragón E, Goerner N, Xi Q, Gomes T, Gao S, Massagué J, Macias MJ. Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-β Pathways. Structure (London, England : 1993). 20: 1726-36. PMID 22921829 DOI: 10.1016/J.Str.2012.07.014  0.412
2012 Chen Q, Massagué J. Molecular pathways: VCAM-1 as a potential therapeutic target in metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 5520-5. PMID 22879387 DOI: 10.1158/1078-0432.Ccr-11-2904  0.389
2012 Aggarwal K, Massagué J. Ubiquitin removal in the TGF-β pathway. Nature Cell Biology. 14: 656-7. PMID 22743709 DOI: 10.1038/Ncb2534  0.397
2012 Massagué J, Xi Q. TGF-β control of stem cell differentiation genes. Febs Letters. 586: 1953-8. PMID 22710171 DOI: 10.1016/J.Febslet.2012.03.023  0.372
2012 Huang J, Li YM, Massague J, Sicheneder A, Vallera DA, Hall WA. Intracerebral infusion of the bispecific targeted toxin DTATEGF in a mouse xenograft model of a human metastatic non-small cell lung cancer. Journal of Neuro-Oncology. 109: 229-38. PMID 22696210 DOI: 10.1007/S11060-012-0904-6  0.333
2012 Massagué J. TGF-β signaling in development and disease. Febs Letters. 586: 1833. PMID 22651913 DOI: 10.1016/J.Febslet.2012.05.030  0.328
2012 Oskarsson T, Massagué J. Extracellular matrix players in metastatic niches. The Embo Journal. 31: 254-6. PMID 22179697 DOI: 10.1038/Emboj.2011.469  0.349
2012 Acharyya S, Oskarsson T, Vanharanta S, Malladi S, Kim J, Brogi E, Norton L, Massague J. Abstract B40: Paracrine interactions through CXCL1/2 chemokines promote breast cancer metastasis and chemoresistance Clinical Cancer Research. 18: B40-B40. DOI: 10.1158/1078-0432.Mechres-B40  0.369
2011 Lu X, Mu E, Wei Y, Riethdorf S, Yang Q, Yuan M, Yan J, Hua Y, Tiede BJ, Lu X, Haffty BG, Pantel K, Massagué J, Kang Y. VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors. Cancer Cell. 20: 701-14. PMID 22137794 DOI: 10.1016/J.Ccr.2011.11.002  0.529
2011 Chen Q, Zhang XH, Massagué J. Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs. Cancer Cell. 20: 538-49. PMID 22014578 DOI: 10.1016/J.Ccr.2011.08.025  0.381
2011 Gucalp A, Sparano JA, Caravelli J, Santamauro J, Patil S, Abbruzzi A, Pellegrino C, Bromberg J, Dang C, Theodoulou M, Massague J, Norton L, Hudis C, Traina TA. Phase II trial of saracatinib (AZD0530), an oral SRC-inhibitor for the treatment of patients with hormone receptor-negative metastatic breast cancer. Clinical Breast Cancer. 11: 306-11. PMID 21729667 DOI: 10.1016/J.Clbc.2011.03.021  0.304
2011 Aragón E, Goerner N, Zaromytidou AI, Xi Q, Escobedo A, Massagué J, Macias MJ. A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes & Development. 25: 1275-88. PMID 21685363 DOI: 10.1101/Gad.2060811  0.376
2011 Comen E, Norton L, Massagué J. Clinical implications of cancer self-seeding. Nature Reviews. Clinical Oncology. 8: 369-77. PMID 21522121 DOI: 10.1038/Nrclinonc.2011.64  0.305
2011 Fang F, Turcan S, Rimner A, Kaufman A, Giri D, Morris LG, Shen R, Seshan V, Mo Q, Heguy A, Baylin SB, Ahuja N, Viale A, Massague J, Norton L, et al. Breast cancer methylomes establish an epigenomic foundation for metastasis. Science Translational Medicine. 3: 75ra25. PMID 21430268 DOI: 10.1126/Scitranslmed.3001875  0.306
2011 Schultz N, Marenstein DR, De Angelis DA, Wang WQ, Nelander S, Jacobsen A, Marks DS, Massagué J, Sander C. Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2. Silence. 2: 3. PMID 21401928 DOI: 10.1186/1758-907X-2-3  0.319
2011 Dorn DC, He W, Massague J, Moore MAS. TIF1γ Knockdown Enhances Hematopoietic Stem Cell Self Renewal with Preferential Myeloid Differentiation and Delayed Erythropoiesis Blood. 118: 4829-4829. DOI: 10.1182/Blood.V118.21.4829.4829  0.338
2011 Sevenich L, Mason S, Rapaport F, Massague J, Leslie C, Joyce J. Abstract 2844: Systems biology analysis of tumor and stromal genes in different metastatic microenvironments Cancer Research. 71: 2844-2844. DOI: 10.1158/1538-7445.Am2011-2844  0.342
2010 Arnal-Estapé A, Tarragona M, Morales M, Guiu M, Nadal C, Massagué J, Gomis RR. HER2 silences tumor suppression in breast cancer cells by switching expression of C/EBPß isoforms. Cancer Research. 70: 9927-36. PMID 21098707 DOI: 10.1158/0008-5472.Can-10-0869  0.405
2010 Bos PD, Nguyen DX, Massagué J. Modeling metastasis in the mouse. Current Opinion in Pharmacology. 10: 571-7. PMID 20598638 DOI: 10.1016/J.Coph.2010.06.003  0.688
2010 Oskarsson T, Nagorny P, Krauss IJ, Perez L, Mandal M, Yang G, Ouerfelli O, Xiao D, Moore MA, Massagué J, Danishefsky SJ. Diverted total synthesis leads to the generation of promising cell-migration inhibitors for treatment of tumor metastasis: in vivo and mechanistic studies on the migrastatin core ether analog. Journal of the American Chemical Society. 132: 3224-8. PMID 20155906 DOI: 10.1021/Ja9101503  0.325
2010 Lu X, Yang Q, Yuan M, Mu E, Reiss M, Haffty B, Massagué J, Kang Y. Abstract 5763: VCAM1 mediates aggressive bone metastasis outbreak from tumor dormancy by engaging α4β1-positive osteoclast progenitor cells Cancer Research. 70: 5763-5763. DOI: 10.1158/1538-7445.Am10-5763  0.533
2009 Kim MY, Oskarsson T, Acharyya S, Nguyen DX, Zhang XH, Norton L, Massagué J. Tumor self-seeding by circulating cancer cells. Cell. 139: 1315-26. PMID 20064377 DOI: 10.1016/J.Cell.2009.11.025  0.307
2009 Gao S, Alarcón C, Sapkota G, Rahman S, Chen PY, Goerner N, Macias MJ, Erdjument-Bromage H, Tempst P, Massagué J. Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling. Molecular Cell. 36: 457-68. PMID 19917253 DOI: 10.1016/J.Molcel.2009.09.043  0.791
2009 Lu X, Wang Q, Hu G, Van Poznak C, Fleisher M, Reiss M, Massagué J, Kang Y. ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis. Genes & Development. 23: 1882-94. PMID 19608765 DOI: 10.1101/Gad.1824809  0.552
2009 Zhang XH, Wang Q, Gerald W, Hudis CA, Norton L, Smid M, Foekens JA, Massagué J. Latent bone metastasis in breast cancer tied to Src-dependent survival signals. Cancer Cell. 16: 67-78. PMID 19573813 DOI: 10.1016/J.Ccr.2009.05.017  0.365
2009 Bos PD, Zhang XH, Nadal C, Shu W, Gomis RR, Nguyen DX, Minn AJ, van de Vijver MJ, Gerald WL, Foekens JA, Massagué J. Genes that mediate breast cancer metastasis to the brain. Nature. 459: 1005-9. PMID 19421193 DOI: 10.1038/Nature08021  0.698
2009 Nguyen DX, Bos PD, Massagué J. Metastasis: from dissemination to organ-specific colonization. Nature Reviews. Cancer. 9: 274-84. PMID 19308067 DOI: 10.1038/Nrc2622  0.685
2009 Padua D, Massagué J. Roles of TGFbeta in metastasis. Cell Research. 19: 89-102. PMID 19050696 DOI: 10.1038/Cr.2008.316  0.716
2009 Massagué J. Abstract IA-19: Deconstructing metastasis Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-Ia-19  0.368
2008 Massagué J. TGFbeta in Cancer. Cell. 134: 215-30. PMID 18662538 DOI: 10.1016/J.Cell.2008.07.001  0.406
2008 Padua D, Zhang XH, Wang Q, Nadal C, Gerald WL, Gomis RR, Massagué J. TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Cell. 133: 66-77. PMID 18394990 DOI: 10.1016/J.Cell.2008.01.046  0.707
2008 Massagué J. A very private TGF-beta receptor embrace. Molecular Cell. 29: 149-50. PMID 18243107 DOI: 10.1016/J.Molcel.2008.01.006  0.392
2008 Xi Q, He W, Zhang XH, Le HV, Massagué J. Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program. The Journal of Biological Chemistry. 283: 1146-55. PMID 18003620 DOI: 10.1074/Jbc.M707479200  0.38
2008 Siegel PM, Massagué J. 11 Growth Control by TGF-β: Mechanisms Controlling Cell Cycle Progression and Apoptosis Cold Spring Harbor Monograph Archive. 50: 333-362. DOI: 10.1101/087969752.50.333  0.378
2007 Gupta GP, Perk J, Acharyya S, de Candia P, Mittal V, Todorova-Manova K, Gerald WL, Brogi E, Benezra R, Massagué J. ID genes mediate tumor reinitiation during breast cancer lung metastasis. Proceedings of the National Academy of Sciences of the United States of America. 104: 19506-11. PMID 18048329 DOI: 10.1073/Pnas.0709185104  0.651
2007 Nguyen DX, Massagué J. Genetic determinants of cancer metastasis. Nature Reviews. Genetics. 8: 341-52. PMID 17440531 DOI: 10.1038/Nrg2101  0.321
2007 Minn AJ, Gupta GP, Padua D, Bos P, Nguyen DX, Nuyten D, Kreike B, Zhang Y, Wang Y, Ishwaran H, Foekens JA, van de Vijver M, Massagué J. Lung metastasis genes couple breast tumor size and metastatic spread. Proceedings of the National Academy of Sciences of the United States of America. 104: 6740-5. PMID 17420468 DOI: 10.1073/Pnas.0701138104  0.773
2007 Sapkota G, Alarcón C, Spagnoli FM, Brivanlou AH, Massagué J. Balancing BMP signaling through integrated inputs into the Smad1 linker. Molecular Cell. 25: 441-54. PMID 17289590 DOI: 10.1016/J.Molcel.2007.01.006  0.791
2007 Massagué J. Sorting out breast-cancer gene signatures. The New England Journal of Medicine. 356: 294-7. PMID 17229957 DOI: 10.1056/Nejme068292  0.315
2007 Li F, Tiede B, Massagué J, Kang Y. Beyond tumorigenesis: cancer stem cells in metastasis. Cell Research. 17: 3-14. PMID 17179981 DOI: 10.1038/Sj.Cr.7310118  0.534
2006 Gupta GP, Massagué J. Cancer metastasis: building a framework. Cell. 127: 679-95. PMID 17110329 DOI: 10.1016/J.Cell.2006.11.001  0.623
2006 Sapkota G, Knockaert M, Alarcón C, Montalvo E, Brivanlou AH, Massagué J. Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways. The Journal of Biological Chemistry. 281: 40412-9. PMID 17085434 DOI: 10.1074/Jbc.M610172200  0.793
2006 Gomis RR, Alarcón C, Nadal C, Van Poznak C, Massagué J. C/EBPbeta at the core of the TGFbeta cytostatic response and its evasion in metastatic breast cancer cells. Cancer Cell. 10: 203-14. PMID 16959612 DOI: 10.1016/J.Ccr.2006.07.019  0.771
2006 Norton L, Massagué J. Is cancer a disease of self-seeding? Nature Medicine. 12: 875-8. PMID 16892025 DOI: 10.1038/Nm0806-875  0.307
2006 Knockaert M, Sapkota G, Alarcón C, Massagué J, Brivanlou AH. Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling. Proceedings of the National Academy of Sciences of the United States of America. 103: 11940-5. PMID 16882717 DOI: 10.1073/Pnas.0605133103  0.804
2006 He W, Dorn DC, Erdjument-Bromage H, Tempst P, Moore MA, Massagué J. Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway. Cell. 125: 929-41. PMID 16751102 DOI: 10.1016/J.Cell.2006.03.045  0.433
2006 Massagué J, Gomis RR. The logic of TGFbeta signaling. Febs Letters. 580: 2811-20. PMID 16678165 DOI: 10.1016/J.Febslet.2006.04.033  0.395
2006 Kang Y, He W, Tulley S, Gupta GP, Serganova I, Chen CR, Manova-Todorova K, Blasberg R, Gerald WL, Massagué J. Erratum: Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway (Proceedings of the National Academy of Sciences of the United States of America) (September 27, 2005) 102 (13909-13914) DOI: 10.1073/pnas.0506517102)) Proceedings of the National Academy of Sciences of the United States of America. 103. DOI: 10.1073/Pnas.0603221103  0.526
2005 Massagué J, Seoane J, Wotton D. Smad transcription factors. Genes & Development. 19: 2783-810. PMID 16322555 DOI: 10.1101/Gad.1350705  0.388
2005 Thomas DA, Massagué J. TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. Cancer Cell. 8: 369-80. PMID 16286245 DOI: 10.1016/J.Ccr.2005.10.012  0.401
2005 Kang Y, He W, Tulley S, Gupta GP, Serganova I, Chen CR, Manova-Todorova K, Blasberg R, Gerald WL, Massagué J. Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway. Proceedings of the National Academy of Sciences of the United States of America. 102: 13909-14. PMID 16172383 DOI: 10.1073/Pnas.0506517102  0.725
2005 Minn AJ, Kang Y, Serganova I, Gupta GP, Giri DD, Doubrovin M, Ponomarev V, Gerald WL, Blasberg R, Massagué J. Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. The Journal of Clinical Investigation. 115: 44-55. PMID 15630443 DOI: 10.1172/Jci22320  0.696
2004 Gupta GP, Massagué J. Platelets and metastasis revisited: a novel fatty link. The Journal of Clinical Investigation. 114: 1691-3. PMID 15599391 DOI: 10.1172/JCI23823  0.581
2004 Massagué J. G1 cell-cycle control and cancer. Nature. 432: 298-306. PMID 15549091 DOI: 10.1038/Nature03094  0.324
2004 Scandura JM, Boccuni P, Massagué J, Nimer SD. Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation. Proceedings of the National Academy of Sciences of the United States of America. 101: 15231-6. PMID 15477587 DOI: 10.1073/Pnas.0406771101  0.363
2004 Kang Y, Massagué J. Epithelial-mesenchymal transitions: twist in development and metastasis. Cell. 118: 277-9. PMID 15294153 DOI: 10.1016/J.Cell.2004.07.011  0.538
2004 Calonge MJ, Seoane J, Massagué J. Opposite Smad and chicken ovalbumin upstream promoter transcription factor inputs in the regulation of the collagen VII gene promoter by transforming growth factor-beta. The Journal of Biological Chemistry. 279: 23759-65. PMID 15047696 DOI: 10.1074/Jbc.M402178200  0.408
2004 Xu L, Massagué J. Nucleocytoplasmic shuttling of signal transducers. Nature Reviews. Molecular Cell Biology. 5: 209-19. PMID 14991001 DOI: 10.1038/Nrm1331  0.324
2004 Massagué J, Attisano L, Wrana JL. The TGF-beta family and its composite receptors. Trends in Cell Biology. 4: 172-8. PMID 14731645 DOI: 10.1016/0962-8924(94)90202-X  0.745
2004 Gupta GP, Massagué J. Platelets and metastasis revisited: a novel fatty link Journal of Clinical Investigation. 114: 1691-1693. DOI: 10.1172/Jci200423823  0.328
2004 Scandura JM, Boccuni P, Massagué J, Nimer SD. Erratum: Transforming growth factor β-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation (Proceedings of the National Academy of Sciences of the United States of America (October 19, 2004) 101, 42 (15231-15236)) Proceedings of the National Academy of Sciences of the United States of America. 101. DOI: 10.1073/Pnas.0407769101  0.338
2003 Massague J. Integration of Smad and MAPK pathways: a link and a linker revisited. Genes & Development. 17: 2993-7. PMID 14701870 DOI: 10.1101/Gad.1167003  0.349
2003 Foletta VC, Lim MA, Soosairajah J, Kelly AP, Stanley EG, Shannon M, He W, Das S, Massague J, Bernard O, Soosairaiah J. Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1. The Journal of Cell Biology. 162: 1089-98. PMID 12963706 DOI: 10.1083/Jcb.200212060  0.382
2003 Xu L, Alarcón C, Cöl S, Massagué J. Distinct domain utilization by Smad3 and Smad4 for nucleoporin interaction and nuclear import. The Journal of Biological Chemistry. 278: 42569-77. PMID 12917407 DOI: 10.1074/Jbc.M307601200  0.787
2003 Shi Y, Massagué J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell. 113: 685-700. PMID 12809600 DOI: 10.1016/S0092-8674(03)00432-X  0.437
2003 Kang Y, Chen CR, Massagué J. A self-enabling TGFbeta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells. Molecular Cell. 11: 915-26. PMID 12718878 DOI: 10.1016/S1097-2765(03)00109-6  0.532
2003 Chai J, Wu JW, Yan N, Massagué J, Pavletich NP, Shi Y. Features of a Smad3 MH1-DNA complex: Roles of water and zinc in DNA binding Journal of Biological Chemistry. 278: 20327-20331. PMID 12686552 DOI: 10.1074/Jbc.C300134200  0.31
2002 Blain SW, Massagué J. Breast cancer banishes p27 from nucleus. Nature Medicine. 8: 1076-8. PMID 12357238 DOI: 10.1038/Nm1002-1076  0.305
2002 Xu L, Kang Y, Cöl S, Massagué J. Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus. Molecular Cell. 10: 271-82. PMID 12191473 DOI: 10.1016/S1097-2765(02)00586-5  0.571
2002 López-Rovira T, Chalaux E, Massagué J, Rosa JL, Ventura F. Direct binding of Smad1 and Smad4 to two distinct motifs mediates bone morphogenetic protein-specific transcriptional activation of Id1 gene. The Journal of Biological Chemistry. 277: 3176-85. PMID 11700304 DOI: 10.1074/Jbc.M106826200  0.36
2001 Wu JW, Hu M, Chai J, Seoane J, Huse M, Li C, Rigotti DJ, Kyin S, Muir TW, Fairman R, Massagué J, Shi Y. Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling. Molecular Cell. 8: 1277-89. PMID 11779503 DOI: 10.1016/S1097-2765(01)00421-X  0.428
2001 Huse M, Muir TW, Xu L, Chen YG, Kuriyan J, Massagué J. The TGF beta receptor activation process: an inhibitor- to substrate-binding switch. Molecular Cell. 8: 671-82. PMID 11583628 DOI: 10.1016/S1097-2765(01)00332-X  0.378
2001 Seoane J, Pouponnot C, Staller P, Schader M, Eilers M, Massagué J. TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b. Nature Cell Biology. 3: 400-8. PMID 11283614 DOI: 10.1038/35070086  0.416
2001 Staller P, Peukert K, Kiermaier A, Seoane J, Lukas J, Karsunky H, Möröy T, Bartek J, Massagué J, Hänel F, Eilers M. Repression of p15INK4b expression by Myc through association with Miz-1. Nature Cell Biology. 3: 392-9. PMID 11283613 DOI: 10.1038/35070076  0.336
2001 Lo RS, Wotton D, Massagué J. Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF Embo Journal. 20: 128-136. PMID 11226163 DOI: 10.1093/Emboj/20.1.128  0.408
2001 Chen CR, Kang Y, Massagué J. Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor β growth arrest program Proceedings of the National Academy of Sciences of the United States of America. 98: 992-999. PMID 11158583 DOI: 10.1073/Pnas.98.3.992  0.587
2000 Serrano M, Massagué J. Networks of tumor suppressors Embo Reports. 1: 115-119. PMID 11265748 DOI: 10.1093/Embo-Reports/Kvd034  0.338
2000 Massagué J. How cells read TGF-beta signals. Nature Reviews Molecular Cell Biology. 1: 169-178. PMID 11252892 DOI: 10.1038/35043051  0.405
2000 Jakubowiak A, Pouponnot C, Berguido F, Frank R, Mao S, Massagué J, Nimer SD. Inhibition of the Transforming Growth Factor β1 Signaling Pathway by the AML1/ETO Leukemia-associated Fusion Protein Journal of Biological Chemistry. 275: 40282-40287. PMID 11032826 DOI: 10.1074/Jbc.C000485200  0.392
2000 Jayaraman L, Massagué J. Distinct oligomeric states of SMAD proteins in the transforming growth factor-beta pathway. Journal of Biological Chemistry. 275: 40710-40717. PMID 11018029 DOI: 10.1074/Jbc.M005799200  0.411
2000 Dou C, Lee J, Liu B, Liu F, Massague J, Xuan S, Lai E. BF-1 Interferes with Transforming Growth Factor β Signaling by Associating with Smad Partners Molecular and Cellular Biology. 20: 6201-6211. PMID 10938097 DOI: 10.1128/Mcb.20.17.6201-6211.2000  0.391
2000 Blain SW, Massagué J. Different Sensitivity of the Transforming Growth Factor-β Cell Cycle Arrest Pathway to c-Myc and MDM-2 Journal of Biological Chemistry. 275: 32066-32070. PMID 10906337 DOI: 10.1074/Jbc.M006496200  0.375
2000 Gouédard L, Chen Y, Thevenet L, Racine C, Borie S, Lamarre I, Josso N, Massagué J, Clemente Nd. Engagement of bone morphogenetic protein type IB receptor and Smad1 signaling by anti-Müllerian hormone and its type II receptor. Journal of Biological Chemistry. 275: 27973-27978. PMID 10854429 DOI: 10.1074/Jbc.M002704200  0.366
2000 Gripp KW, Wotton D, Edwards MC, Roessler E, Ades L, Meinecke P, Richieri-Costa A, Zackai EH, Massagué J, Muenke M, Elledge SJ. Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination Nature Genetics. 25: 205-208. PMID 10835638 DOI: 10.1038/76074  0.363
2000 Massagué J, Wotton D. Transcriptional control by the TGF-β/Smad signaling system Embo Journal. 19: 1745-1754. PMID 10775259 DOI: 10.1093/Emboj/19.8.1745  0.361
2000 Hata A, Seoane J, Lagna G, Montalvo E, Hemmati-Brivanlou A, Massagué J. OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways. Cell. 100: 229-40. PMID 10660046 DOI: 10.1016/S0092-8674(00)81561-5  0.721
2000 Massagué J, Chen Y. Controlling TGF-β signaling Genes & Development. 14: 627-644. DOI: 10.1101/Gad.14.6.627  0.334
1999 Wotton D, Lo RS, Swaby LAC, Massagué J. Multiple modes of repression by the Smad transcriptional corepressor TGIF Journal of Biological Chemistry. 274: 37105-37110. PMID 10601270 DOI: 10.1074/Jbc.274.52.37105  0.315
1999 Lo RS, Massagué J. Ubiquitin-dependent degradation of TGF-β-activated Smad2 Nature Cell Biology. 1: 472-478. PMID 10587642 DOI: 10.1038/70258  0.392
1999 Calonge MJ, Massagué J. Smad4/DPC4 silencing and hyperactive Ras jointly disrupt transforming growth factor-beta antiproliferative responses in colon cancer cells. Journal of Biological Chemistry. 274: 33637-33643. PMID 10559252 DOI: 10.1074/Jbc.274.47.33637  0.442
1999 Onichtchouk D, Chen YG, Dosch R, Gawantka V, Delius H, Massagué J, Niehrs C. Silencing of TGF-beta signalling by the pseudoreceptor BAMBI. Nature. 401: 480-485. PMID 10519551 DOI: 10.1038/46794  0.448
1999 Warner BJ, Blain SW, Seoane J, Massagué J. Myc Downregulation by Transforming Growth Factor β Required for Activation of the p15Ink4b G1 Arrest Pathway Molecular and Cellular Biology. 19: 5913-5922. PMID 10454538 DOI: 10.1128/Mcb.19.9.5913  0.379
1999 Wotton D, Lo RS, Lee S, Massagué J. A Smad transcriptional corepressor Cell. 97: 29-39. PMID 10199400 DOI: 10.1016/S0092-8674(00)80712-6  0.345
1999 Kretzschmar M, Doody J, Timokhina I, Massagué J. A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras. Genes & Development. 13: 804-816. PMID 10197981 DOI: 10.1101/Gad.13.7.804  0.34
1999 Ulloa L, Doody J, Massagué J. Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway. Nature. 397: 710-713. PMID 10067896 DOI: 10.1038/17826  0.429
1999 Huse M, Chen YG, Massagué J, Kuriyan J. Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12. Cell. 96: 425-36. PMID 10025408 DOI: 10.1016/S0092-8674(00)80555-3  0.375
1999 Chen Y, Massagué J. Smad1 Recognition and Activation by the ALK1 Group of Transforming Growth Factor-β Family Receptors Journal of Biological Chemistry. 274: 3672-3677. PMID 9920917 DOI: 10.1074/Jbc.274.6.3672  0.382
1999 Yin JJ, Selander K, Chirgwin JM, Dallas M, Grubbs BG, Wieser R, Massagué J, Mundy GR, Guise TA. TGF-beta signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. The Journal of Clinical Investigation. 103: 197-206. PMID 9916131 DOI: 10.1172/Jci3523  0.456
1999 Iavarone A, Massagué J. E2F and Histone Deacetylase Mediate Transforming Growth Factor β Repression of cdc25A during Keratinocyte Cell Cycle Arrest Molecular and Cellular Biology. 19: 916-922. PMID 9858615 DOI: 10.1128/Mcb.19.1.916  0.416
1998 Massagué J. TGF-beta signal transduction. Annual Review of Biochemistry. 67: 753-91. PMID 9759503 DOI: 10.1146/ANNUREV.BIOCHEM.67.1.753  0.347
1998 Shi Y, Wang YF, Jayaraman L, Yang H, Massagué J, Pavletich NP. Crystal structure of a Smad MH1 domain bound to DNA: Insights on DNA binding in TGF-β signaling Cell. 94: 585-594. PMID 9741623 DOI: 10.1016/S0092-8674(00)81600-1  0.378
1998 Pouponnot C, Jayaraman L, Massagué J. Physical and Functional Interaction of SMADs and p300/CBP Journal of Biological Chemistry. 273: 22865-22868. PMID 9722503 DOI: 10.1074/Jbc.273.36.22865  0.38
1998 Hata A, Shi Y, Massagué J. TGF-beta signaling and cancer: structural and functional consequences of mutations in Smads. Molecular Medicine Today. 4: 257-62. PMID 9679244 DOI: 10.1016/S1357-4310(98)01247-7  0.434
1998 Chen YG, Hata A, Lo RS, Wotton D, Shi Y, Pavletich N, Massagué J. Determinants of specificity in TGF-β signal transduction Genes and Development. 12: 2144-2152. PMID 9679059 DOI: 10.1101/Gad.12.14.2144  0.459
1998 Kretzschmar M, Massagué J. SMADs: mediators and regulators of TGF-β signaling Current Opinion in Genetics & Development. 8: 103-111. PMID 9529613 DOI: 10.1016/S0959-437X(98)80069-5  0.446
1998 Lo RS, Chen YG, Shi Y, Pavletich NP, Massagué J. The L3 loop: A structural motif determining specific interactions between SMAD proteins and TGF-β receptors Embo Journal. 17: 996-1005. PMID 9463378 DOI: 10.1093/Emboj/17.4.996  0.441
1998 Hata A, Lagna G, Massagué J, Hemmati-Brivanlou A. Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor Genes & Development. 12: 186-197. PMID 9436979 DOI: 10.1101/Gad.12.2.186  0.698
1997 Chen Y, Liu F, Massagué J. Mechanism of TGFbeta receptor inhibition by FKBP12. The Embo Journal. 16: 3866-3876. PMID 9233797 DOI: 10.1093/Emboj/16.13.3866  0.391
1997 Shi Y, Hata A, Lo RS, Massagué J, Pavletich NP. A structural basis for mutational inactivation of the tumour suppressor Smad4 Nature. 388: 87-93. PMID 9214508 DOI: 10.1038/40431  0.415
1997 Hata A, Lo RS, Wotton D, Lagna G, Massagué J. Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4 Nature. 388: 82-87. PMID 9214507 DOI: 10.1038/40424  0.714
1997 lavarone A, Massagué J. Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-β in cells lacking the CDK inhibitor p15 Nature. 387: 417-422. PMID 9163429 DOI: 10.1038/387417A0  0.372
1997 Kretzschmar M, Liu F, Hata A, Doody J, Massagué J. The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase. Genes & Development. 11: 984-995. PMID 9136927 DOI: 10.1101/Gad.11.8.984  0.459
1997 Luo Y, Marx SO, Kiyokawa H, Koff A, Massagué J, Marks AR. Rapamycin resistance tied to defective regulation of p27Kip1. Molecular and Cellular Biology. 16: 6744-51. PMID 8943329 DOI: 10.1128/Mcb.16.12.6744  0.348
1996 Lagna G, Hata A, Hemmati-Brivanlou A, Massagué J. Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. Nature. 383: 832-6. PMID 8893010 DOI: 10.1038/383832A0  0.463
1996 Massagué J. TGFβ Signaling: Receptors, Transducers, and Mad Proteins Cell. 85: 947-950. PMID 8674122 DOI: 10.1016/S0092-8674(00)81296-9  0.325
1996 Ventura F, Liu F, Doody J, Massagué J. Interaction of Transforming Growth Factor-β Receptor I with Farnesyl-protein Transferase-α in Yeast and Mammalian Cells Journal of Biological Chemistry. 271: 13931-13934. PMID 8663177 DOI: 10.1074/Jbc.271.24.13931  0.388
1996 Liu F, Hata A, Baker JC, Doody J, Cárcamo J, Harland RM, Massagué J. A human Mad protein acting as a BMP-regulated transcriptional activator. Nature. 381: 620-3. PMID 8637600 DOI: 10.1038/381620A0  0.451
1996 Arribas J, Coodly L, Vollmer P, Kishimoto TK, Rose-John S, Massagué J. Diverse Cell Surface Protein Ectodomains Are Shed by a System Sensitive to Metalloprotease Inhibitors Journal of Biological Chemistry. 271: 11376-11382. PMID 8626692 DOI: 10.1074/Jbc.271.19.11376  0.354
1996 Attisano L, Wrana JL, Montalvo E, Massagué J. Activation of signalling by the activin receptor complex. Molecular and Cellular Biology. 16: 1066-73. PMID 8622651 DOI: 10.1128/Mcb.16.3.1066  0.726
1996 Weis-Garcia F, Massagué J. Complementation between kinase-defective and activation-defective TGF-beta receptors reveals a novel form of receptor cooperativity essential for signaling. The Embo Journal. 15: 276-289. DOI: 10.1002/J.1460-2075.1996.Tb00358.X  0.363
1995 Cárcamo J, Zentella A, Massagué J. Disruption of transforming growth factor beta signaling by a mutation that prevents transphosphorylation within the receptor complex. Molecular and Cellular Biology. 15: 1573-1581. PMID 7862150 DOI: 10.1128/Mcb.15.3.1573  0.374
1995 Arribas J, Massagué J. Transforming growth factor-alpha and beta-amyloid precursor protein share a secretory mechanism. Journal of Cell Biology. 128: 433-441. PMID 7844156 DOI: 10.1083/Jcb.128.3.433  0.359
1995 Liu F, Ventura F, Doody J, Massague J. Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs. Molecular and Cellular Biology. 15: 3479-3486. PMID 7791754 DOI: 10.1128/Mcb.15.7.3479  0.408
1995 Luo Y, Hurwitz J, Massagué J. Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1. Nature. 375: 159-61. PMID 7753174 DOI: 10.1038/375159A0  0.322
1995 Massague J, Polyak K. Mammalian anti proliferative signals and their targets Current Opinion in Genetics & Development. 5: 91-96. PMID 7749332 DOI: 10.1016/S0959-437X(95)90059-4  0.403
1995 Letsou A, Arora K, Wrana JL, Simin K, Twombly V, Jamal J, Staehling-Hampton K, Hoffmann FM, Gelbart WM, Massagué J. Drosophila Dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor of the TGF beta receptor family. Cell. 80: 899-908. PMID 7697720 DOI: 10.1016/0092-8674(95)90293-7  0.615
1995 Reynisdóttir I, Polyak K, Iavarone A, Massagué J. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta. Genes & Development. 9: 1831-1845. PMID 7649471 DOI: 10.1101/Gad.9.15.1831  0.362
1995 Wieser R, Wrana J, Massagué J. GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex. The Embo Journal. 14: 2199-2208. DOI: 10.1002/J.1460-2075.1995.Tb07214.X  0.595
1994 Wrana JL, Tran H, Attisano L, Arora K, Childs SR, Massagué J, O'Connor MB. Two distinct transmembrane serine/threonine kinases from Drosophila melanogaster form an activin receptor complex Molecular and Cellular Biology. 14: 944-950. PMID 8289834 DOI: 10.1128/Mcb.14.2.944  0.746
1994 Polyak K, Kato JY, Solomon MJ, Sherr CJ, Massague J, Roberts JM, Koff A. P27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest Genes and Development. 8: 9-22. PMID 8288131 DOI: 10.1101/Gad.8.1.9  0.339
1994 Cárcamo J, Weis FM, Ventura F, Wieser R, Wrana JL, Attisano L, Massagué J. Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin. Molecular and Cellular Biology. 14: 3810-21. PMID 8196624 DOI: 10.1128/Mcb.14.6.3810  0.749
1994 Attisano L, Wrana JL, López-Casillas F, Massagué J. TGF-beta receptors and actions. Biochimica Et Biophysica Acta. 1222: 71-80. PMID 8186268 DOI: 10.1016/0167-4889(94)90026-4  0.721
1994 Nakayama H, Ichikawa F, Andres JL, Massagué J, Noda M. Dexamethasone Enhancement of Betaglycan (TGF-β Type III Receptor) Gene Expression in Osteoblast-like Cells Experimental Cell Research. 211: 301-306. PMID 8143777 DOI: 10.1006/Excr.1994.1091  0.389
1994 López-Casillas F, Payne H, Andres J, Massagué J. Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites Journal of Cell Biology. 124: 557-568. PMID 8106553 DOI: 10.1083/Jcb.124.4.557  0.426
1994 Wrana JL, Attisano L, Wieser R, Ventura F, Massagué J. Mechanism of activation of the TGF-beta receptor. Nature. 370: 341-7. PMID 8047140 DOI: 10.1038/370341A0  0.749
1994 Brummel TJ, Twombly V, Marqués G, Wrana JL, Newfeld SJ, Attisano L, Massagué J, O'Connor MB, Gelbart WM. Characterization and relationship of Dpp receptors encoded by the saxophone and thick veins genes in Drosophila. Cell. 78: 251-61. PMID 8044839 DOI: 10.1016/0092-8674(94)90295-X  0.718
1994 Penton A, Chen Y, Staehling-Hampton K, Wrana JL, Attisano L, Szidonya J, Cassill JA, Massagué J, Hoffmann FM. Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor. Cell. 78: 239-50. PMID 8044838 DOI: 10.1016/0092-8674(94)90294-1  0.727
1994 Polyak K, Lee MH, Erdjument-Bromage H, Koff A, Roberts JM, Tempst P, Massagué J. Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell. 78: 59-66. PMID 8033212 DOI: 10.1016/0092-8674(94)90572-X  0.361
1994 Mathew S, Murty VV, Cheifetz S, George D, Massagué J, Chaganti RS. Transforming growth factor receptor gene TGFBR2 maps to human chromosome band 3p22. Genomics. 20: 114-5. PMID 8020936 DOI: 10.1006/Geno.1994.1134  0.318
1994 Kadin ME, Cavaille-Coll MW, Gertz R, Massague J, Cheifetz S, George D. Loss of receptors for transforming growth factor beta in human T-cell malignancies Proceedings of the National Academy of Sciences of the United States of America. 91: 6002-6006. PMID 8016105 DOI: 10.1073/Pnas.91.13.6002  0.433
1994 Kato JY, Matsuoka M, Polyak K, Massagué J, Sherr CJ. Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation Cell. 79: 487-496. PMID 7954814 DOI: 10.1016/0092-8674(94)90257-7  0.305
1994 Ventura F, Doody J, Liu F, Wrana J, Massagué J. Reconstitution and transphosphorylation of TGF-beta receptor complexes. The Embo Journal. 13: 5581-5589. DOI: 10.1002/J.1460-2075.1994.Tb06895.X  0.559
1993 Koff A, Ohtsuki M, Polyak K, Roberts JM, Massagué J. Negative regulation of G1 in mammalian cells: Inhibition of cyclin E-dependent kinase by TGF-β Science. 260. PMID 8475385 DOI: 10.1126/Science.8475385  0.361
1993 Childs SR, Wrana JL, Arora K, Attisano L, O'Connor MB, Massagué J. Identification of a Drosophila activin receptor Proceedings of the National Academy of Sciences of the United States of America. 90: 9475-9479. PMID 8415726 DOI: 10.1073/Pnas.90.20.9475  0.735
1993 López-Casillas F, Wrana JL, Massagué J. Betaglycan presents ligand to the TGF beta signaling receptor. Cell. 73: 1435-44. PMID 8391934 DOI: 10.1016/0092-8674(93)90368-Z  0.618
1993 Bellón T, Corbí A, Lastres P, Calés C, Cebrián M, Vera S, Cheifetz S, Massague J, Letarte M, Bernabéu C. Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions. European Journal of Immunology. 23: 2340-5. PMID 8370410 DOI: 10.1002/Eji.1830230943  0.395
1993 Wieser R, Attisano L, Wrana JL, Massagué J. Signaling activity of transforming growth factor beta type II receptors lacking specific domains in the cytoplasmic region. Molecular and Cellular Biology. 13: 7239-47. PMID 8246946 DOI: 10.1128/Mcb.13.12.7239  0.74
1993 Attisano L, Cárcamo J, Ventura F, Weis FM, Massagué J, Wrana JL. Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors. Cell. 75: 671-80. PMID 8242742 DOI: 10.1016/0092-8674(93)90488-C  0.742
1993 Bosenberg MW, Massagué J. Juxtacrine cell signaling molecules Current Opinion in Cell Biology. 5: 832-838. PMID 7694603 DOI: 10.1016/0955-0674(93)90032-L  0.355
1993 Wrana JL, Cárcamo J, Attisano L, Cheifetz S, Zentella A, López-Casillas F, Massagué J. The type II TGF-beta receptor signals diverse responses in cooperation with the type I receptor. Cold Spring Harbor Symposia On Quantitative Biology. 57: 81-6. PMID 1339707 DOI: 10.1101/Sqb.1992.057.01.011  0.729
1993 Wrana JL, Attisano L, Cárcamo J, Zentella A, Doody J, Laiho M, Wang XF, Massagué J. TGF beta signals through a heteromeric protein kinase receptor complex. Cell. 71: 1003-14. PMID 1333888 DOI: 10.1016/0092-8674(92)90395-S  0.748
1993 López-Casillas F, Wrana J, Massagué J. Receptor of the third kind Trends in Cell Biology. 3: 334. DOI: 10.1016/0962-8924(93)90100-F  0.533
1992 Ohtsuki M, Massagué J. Evidence for the involvement of protein kinase activity in transforming growth factor-beta signal transduction. Molecular and Cellular Biology. 12: 261-265. PMID 1729603 DOI: 10.1128/Mcb.12.1.261  0.398
1992 Massagué J, Weinberg RA. Negative regulators of growth. Current Opinion in Genetics & Development. 2: 28-32. PMID 1633423 DOI: 10.1016/S0959-437X(05)80317-X  0.358
1992 Zentella A, Massague J. Transforming growth factor beta induces myoblast differentiation in the presence of mitogens Proceedings of the National Academy of Sciences of the United States of America. 89: 5176-5180. PMID 1594628 DOI: 10.1073/Pnas.89.11.5176  0.385
1992 Bosenberg MW, Pandiella A, Massagué J. The cytoplasmic carboxy-terminal amino acid specifies cleavage of membrane TGFα into soluble growth factor Cell. 71: 1157-1165. PMID 1473151 DOI: 10.1016/S0092-8674(05)80064-9  0.31
1992 Massagué J, Andres J, Attisano L, Cheifetz S, López-Casillas F, Ohtsuki M, Wrana JL. TGF-beta receptors. Molecular Reproduction and Development. 32: 99-104. PMID 1322148 DOI: 10.1002/Mrd.1080320204  0.75
1992 Massagué J. Receptors for the TGF-β family Cell. 69: 1067-1070. PMID 1319842 DOI: 10.1016/0092-8674(92)90627-O  0.346
1992 Attisano L, Wrana JL, Cheifetz S, Massagué J. Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors. Cell. 68: 97-108. PMID 1310075 DOI: 10.1016/0092-8674(92)90209-U  0.712
1991 Laiho M, Rönnstrand L, Heino J, Decaprio JA, Ludlow JW, Livingston DM, Massagué J. Control of JunB and Extracellular Matrix Protein Expression by Transforming Growth Factor-β1 Is Independent of Simian Virus 40 T Antigen-Sensitive Growth-Inhibitory Events Molecular and Cellular Biology. 11: 972-978. PMID 1990295 DOI: 10.1128/Mcb.11.2.972  0.382
1991 Zentella A, Weis FMB, Ralph DA, Laiho M, Massagué J. Early gene responses to transforming growth factor-beta in cells lacking growth-suppressive RB function. Molecular and Cellular Biology. 11: 4952-4958. PMID 1922028 DOI: 10.1128/Mcb.11.10.4952  0.404
1991 López-Casillas F, Cheifetz S, Doody J, Andres JL, Lane WS, Massague J. Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system Cell. 67: 785-795. PMID 1657406 DOI: 10.1016/0092-8674(91)90073-8  0.369
1991 Massagué J, Heino J, Laiho M. Mechanisms in TGF-beta action. Ciba Foundation Symposium. 157: 51-9; discussion 59-. PMID 1649037 DOI: 10.1002/9780470514061.ch4  0.339
1990 Anklesaria P, Teixido J, Laiho M, Pierce JH, Greenberger JS, Massague J. Cell-cell adhesion mediated by binding of membrane-anchored transforming growth factor alpha to epidermal growth factor receptors promotes cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 87: 3289-3293. PMID 2333283 DOI: 10.1073/Pnas.87.9.3289  0.383
1990 Massague J. The transforming growth factor-beta family. Annual Review of Cell Biology. 6: 597-641. PMID 2177343 DOI: 10.1146/Annurev.Cb.06.110190.003121  0.337
1990 Massagué J, Cheifetz S, Boyd FT, Andres JL. TGF-beta receptors and TGF-beta binding proteoglycans: recent progress in identifying their functional properties. Annals of the New York Academy of Sciences. 593: 59-72. PMID 2165378 DOI: 10.1111/J.1749-6632.1990.Tb16100.X  0.39
1990 Laiho M, DeCaprio JA, Ludlow JW, Livingston DM, Massague J. Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation Cell. 62: 175-185. PMID 2163767 DOI: 10.1016/0092-8674(90)90251-9  0.374
1990 Boyd FT, Cheifetz S, Andres J, Laiho M, Massagué J. Transforming growth factor-beta receptors and binding proteoglycans. Journal of Cell Science. Supplement. 13: 131-8. PMID 1964683 DOI: 10.1242/Jcs.1990.Supplement_13.12  0.418
1990 Laiho M, Weis MB, Massagué J. Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction. Journal of Biological Chemistry. 265: 18518-18524. DOI: 10.1016/s0021-9258(17)44782-x  0.319
1989 Andres JL, Stanley K, Cheifetz S, Massagué J. Membrane-anchored and soluble forms of betaglycan, a polymorphic proteoglycan that binds transforming growth factor-beta. Journal of Cell Biology. 109: 3137-3145. PMID 2592419 DOI: 10.1083/Jcb.109.6.3137  0.404
1989 Wong ST, Winchell LF, McCune BK, Earp HS, Teixido J, Massague J, Herman B, Lee DC. The TGF-α precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction Cell. 56: 495-506. PMID 2464440 DOI: 10.1016/0092-8674(89)90252-3  0.358
1988 Luetteke NC, Michalopoulos GK, Teixidó J, Gilmore R, Massagué J, Lee DC. Characterization of high molecular weight transforming growth factor α produced by rat hepatocellular carcinoma cells Biochemistry. 27: 6487-6494. PMID 3219349 DOI: 10.1021/Bi00417A043  0.314
1988 Kimchi A, Wang XF, Weinberg RA, Cheifetz S, Massagué J. Absence of TGF-β receptors and growth inhibitory responses in retinoblastoma cells Science. 240: 196-199. PMID 2895499 DOI: 10.1126/Science.2895499  0.403
1987 Ignotz RA, Massagué J. Cell adhesion protein receptors as targets for transforming growth factor-β action Cell. 51: 189-197. PMID 3499229 DOI: 10.1016/0092-8674(87)90146-2  0.4
1987 Massagué J. [10] Purification of type-α transforming growth factor from transformed cells Methods in Enzymology. 146: 103-112. PMID 3479672 DOI: 10.1016/S0076-6879(87)46013-8  0.318
1987 Massagué J. The TGF-β family of growth and differentiation factors Cell. 49: 437-438. PMID 3471351 DOI: 10.1016/0092-8674(87)90443-0  0.327
1987 Massagué J. Identification of receptor proteins for type-alpha transforming growth factor. Methods in Enzymology. 146: 143-153. PMID 3316932 DOI: 10.1016/S0076-6879(87)46016-3  0.372
1987 Massagué J. [17] Identification of receptor for type-β transforming growth factor Methods in Enzymology. 146: 174-195. PMID 2891018 DOI: 10.1016/S0076-6879(87)46020-5  0.385
1987 Massagué J, Cheifetz S, Ignotz RA, Boyd FT. Multiple type-beta transforming growth factors and their receptors. Journal of Cellular Physiology. Supplement. 43-7. PMID 2890647 DOI: 10.1002/Jcp.1041330409  0.424
1987 Ohta M, Greenberger JS, Anklesaria P, Bassols A, Massagué J. Two forms of transforming growth factor-β distinguished by multipotential haematopoietic progenitor cells Nature. 329: 539-541. PMID 2889143 DOI: 10.1038/329539A0  0.366
1987 Cheifetz S, Weatherbee JA, Tsang MLS, Anderson JK, Mole JE, Lucas R, Massagué J. The transforming growth factor-β system, a complex pattern of cross-reactive ligands and receptors Cell. 48: 409-415. PMID 2879635 DOI: 10.1016/0092-8674(87)90192-9  0.351
1986 Centrella M, Massagué J, Canalis E. Human Platelet-Derived Transforming Growth Factor-βStimulates Parameters of Bone Growth in Fetal Rat Calvariae Endocrinology. 119: 2306-2312. PMID 3464414 DOI: 10.1210/Endo-119-5-2306  0.309
1986 Massague J, Cheifetz S, Endo T, Nadal-Ginard B. Type beta transforming growth factor is an inhibitor of myogenic differentiation. Proceedings of the National Academy of Sciences of the United States of America. 83: 8206-8210. PMID 3022285 DOI: 10.1073/Pnas.83.21.8206  0.382
1986 Ignotz RA, Kelly B, Davis RJ, Massagué J. Biologically active precursor for transforming growth factor type alpha, released by retrovirally transformed cells. Proceedings of the National Academy of Sciences of the United States of America. 83: 6307-11. PMID 3018723 DOI: 10.1073/Pnas.83.17.6307  0.507
1986 Massagué J, Kelly B. Internalization of transforming growth factor‐β and its receptor in BALB/c 3T3 fibroblasts Journal of Cellular Physiology. 128: 216-222. PMID 2874147 DOI: 10.1002/Jcp.1041280212  0.405
1985 Ignotz RA, Massagué J. Type beta transforming growth factor controls the adipogenic differentiation of 3T3 fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 82: 8530-8534. PMID 3001708 DOI: 10.1073/Pnas.82.24.8530  0.391
1985 Massagué J. Transforming growth factor-beta modulates the high-affinity receptors for epidermal growth factor and transforming growth factor-alpha. Journal of Cell Biology. 100: 1508-1514. PMID 2985623 DOI: 10.1083/Jcb.100.5.1508  0.423
1985 Davis R, Like B, Massagué J. Modulation of type alpha transforming growth factor receptors by a phorbol ester tumor promoter. Journal of Cellular Biochemistry. 27: 23-30. PMID 2984222 DOI: 10.1002/Jcb.240270104  0.551
1985 Massagué J. The transforming growth factors Trends in Biochemical Sciences. 10: 237-240. DOI: 10.1016/0968-0004(85)90141-0  0.377
1985 Massagué J, Czech MP. [14] Affinity cross-linking of receptors for insulin and the insulin-like growth factors I and II Methods in Enzymology. 109: 179-187. DOI: 10.1016/0076-6879(85)09084-X  0.553
1984 Borland K, Mita M, Oppenheimer CL, Blinderman LA, Massague J, Hall PF, Czech MP. The actions of insulin-like growth factors I and II on cultured Sertoli cells. Endocrinology. 114: 240-6. PMID 6360662 DOI: 10.1210/Endo-114-1-240  0.542
1984 Czech MP, Massagué J, Seals JR, Yu K. CHAPTER 4 – Mechanisms of Biological Signaling by the Insulin Receptor Biochemical Actions of Hormones. 93-125. DOI: 10.1016/B978-0-12-452811-6.50009-8  0.54
1983 Massague J, Freidenberg GF, Olefsky JM, Czech MP. Parallel decreases in the expression of receptors for insulin and insulin-like growth factor I in a mutant human fibroblast line Diabetes. 32: 541-544. PMID 6313454 DOI: 10.2337/Diab.32.6.541  0.546
1983 Massague J, Buxser S, Johnson GL, Czech MP. Affinity labeling of a nerve growth factor receptor component on rat pheochromocytoma (PC12) cells. Biochimica Et Biophysica Acta. 693: 205-12. PMID 6295482 DOI: 10.1016/0005-2736(82)90488-6  0.517
1982 Massague J, Czech MP, Iwata K, DeLarco JE, Todaro GJ. Affinity labeling of a transforming growth factor receptor that does not interact with epidermal growth factor. Proceedings of the National Academy of Sciences of the United States of America. 79: 6822-6. PMID 6294655 DOI: 10.1073/Pnas.79.22.6822  0.574
1981 Czech MP, Massague J, Pilch PF. The insulin receptor: structural features Trends in Biochemical Sciences. 6: 222-225. DOI: 10.1016/0968-0004(81)90081-5  0.665
1980 Czech MP, Massague J, Pilch PF, Carter-Su C. Structural features of the insulin effector system: Relation to hexose transport activation Annals of the New York Academy of Sciences. 282-291. PMID 7011146 DOI: 10.1111/J.1749-6632.1980.Tb15401.X  0.712
1980 Massague J, Pilch PF, Czech MP. Electrophoretic resolution of three major insulin receptor structures with unique subunit stoichiometries Proceedings of the National Academy of Sciences of the United States of America. 77: 7137-7141. PMID 6938960 DOI: 10.1073/Pnas.77.12.7137  0.657
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