| Year |
Citation |
Score |
| 2024 |
Zaidi S, Asalla S, Muturi HT, Russo L, Abdolahipour R, Belew GD, Iglesias MB, Feraudo M, Leon L, Kuo E, Liu X, Kumarasamy S, Ghadieh HE, Gatto-Weis C, Zarrinpar A, ... ... Najjar SM, et al. Loss of CEACAM1 in hepatocytes causes hepatic fibrosis. European Journal of Clinical Investigation. e14177. PMID 38381498 DOI: 10.1111/eci.14177 |
0.462 |
|
| 2023 |
Yeh YT, Sona C, Yan X, Li Y, Pathak A, McDermott MI, Xie Z, Liu L, Arunagiri A, Wang Y, Cazenave-Gassiot A, Ghosh A, von Meyenn F, Kumarasamy S, Najjar SM, et al. Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction. Nature Communications. 14: 4250. PMID 37460527 DOI: 10.1038/s41467-023-39978-1 |
0.721 |
|
| 2023 |
Lee WH, Najjar SM, Kahn CR, Hinds TD. Hepatic insulin receptor: new views on the mechanisms of liver disease. Metabolism: Clinical and Experimental. 145: 155607. PMID 37271372 DOI: 10.1016/j.metabol.2023.155607 |
0.439 |
|
| 2023 |
Ghadieh HE, Gastaldelli A, Najjar SM. Role of Insulin Clearance in Insulin Action and Metabolic Diseases. International Journal of Molecular Sciences. 24. PMID 37108317 DOI: 10.3390/ijms24087156 |
0.436 |
|
| 2023 |
Muturi HT, Ghadieh HE, Abdolahipour R, Stankus HL, Belew GD, Liu JK, Jahromi MS, Lee AD, Singer BB, Angeli-Pahim I, Sehrawat TS, Malhi H, Verhulst S, van Grunsven LA, Zarrinpar A, ... ... Najjar SM, et al. Loss of CEACAM1 in endothelial cells causes hepatic fibrosis. Metabolism: Clinical and Experimental. 155562. PMID 37088122 DOI: 10.1016/j.metabol.2023.155562 |
0.399 |
|
| 2022 |
Najjar SM, Caprio S, Gastaldelli A. Insulin Clearance in Health and Disease. Annual Review of Physiology. PMID 36260807 DOI: 10.1146/annurev-physiol-031622-043133 |
0.471 |
|
| 2022 |
Balakrishnan B, Gupta A, Basri R, Sharma VM, Slayton M, Gentner K, Becker CC, Karki S, Muturi H, Najjar SM, Loria AS, Gokce N, Puri V. Endothelial-Specific Expression of CIDEC Improves High-Fat Diet-Induced Vascular and Metabolic Dysfunction. Diabetes. PMID 36256836 DOI: 10.2337/db22-0294 |
0.333 |
|
| 2022 |
Najjar SM, Abdolahipour R, Ghadieh HE, Jahromi MS, Najjar JA, Abuamreh BAM, Zaidi S, Kumarasamy S, Muturi HT. Regulation of Insulin Clearance by Non-Esterified Fatty Acids. Biomedicines. 10. PMID 36009446 DOI: 10.3390/biomedicines10081899 |
0.478 |
|
| 2022 |
Abu Helal R, Muturi HT, Lee AD, Li W, Ghadieh HE, Najjar SM. Aortic Fibrosis in Insulin-Sensitive Mice with Endothelial Cell-Specific Deletion of Gene. International Journal of Molecular Sciences. 23. PMID 35457157 DOI: 10.3390/ijms23084335 |
0.415 |
|
| 2021 |
Nahle A, Joseph YD, Pereira S, Mori Y, Poon F, Ghadieh HE, Ivovic A, Desai T, Ghanem SS, Asalla S, Muturi HT, Jentz EM, Joseph JW, Najjar SM, Giacca A. Nicotinamide Mononucleotide Prevents Free Fatty Acid-Induced Reduction in Glucose Tolerance by Decreasing Insulin Clearance. International Journal of Molecular Sciences. 22. PMID 34948019 DOI: 10.3390/ijms222413224 |
0.365 |
|
| 2021 |
Muturi HT, Khuder SS, Ghadieh HE, Esakov EL, Noh H, Kang H, McInerney MF, Kim JK, Lee AD, Najjar SM. Insulin Sensitivity Is Retained in Mice with Endothelial Loss of Carcinoembryonic Antigen Cell Adhesion Molecule 1. Cells. 10. PMID 34440862 DOI: 10.3390/cells10082093 |
0.485 |
|
| 2021 |
Helal RA, Russo L, Ghadieh HE, Muturi HT, Asalla S, Lee AD, Gatto-Weis C, Najjar SM. Regulation of hepatic fibrosis by Carcinoembryonic Antigen-related Cell Adhesion Molecule 1. Metabolism: Clinical and Experimental. 154801. PMID 34058224 DOI: 10.1016/j.metabol.2021.154801 |
0.414 |
|
| 2021 |
Roth J, Ashcroft FM, Wollheim CB, Kieffer TJ, Cherrington AD, Bergman RN, Taylor R, Najjar SM, Pedersen O, Ellingsgaard H, Holst JJ, Nauck MA, Kadowaki T, Czech MP, Corvera S, et al. Voices: Insulin and beyond. Cell Metabolism. 33: 692-699. PMID 33826910 DOI: 10.1016/j.cmet.2021.03.017 |
0.392 |
|
| 2020 |
Ghadieh HE, Abu Helal R, Muturi HT, Issa DD, Russo L, Abdallah SL, Najjar JA, Benencia F, Vazquez G, Li W, Najjar SM. Loss of Hepatic Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Links Nonalcoholic Steatohepatitis to Atherosclerosis. Hepatology Communications. 4: 1591-1609. PMID 33163831 DOI: 10.1002/hep4.1590 |
0.513 |
|
| 2020 |
Friedman TC, Shaheen M, Kermah D, Pan D, Schrode K, Najjar SM. SUN-606 Identification of NASH Using Data from NHANES III Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1602 |
0.359 |
|
| 2020 |
Friedman TC, Shaheen M, Kermah D, Pan D, Schrode K, Najjar SM. MON-585 Racial/Ethnic Contribution and Metabolic Factors of NAFLD/NASH in the US Population: Data from NNANES III Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1594 |
0.326 |
|
| 2019 |
Salaheldeen E, Jaume A, Najjar SM. Carcinoembryonic Cell Adhesion-Related Molecule 2 Regulates Insulin Secretion and Energy Balance International Journal of Molecular Sciences. 20: 3231. PMID 31266142 DOI: 10.3390/Ijms20133231 |
0.508 |
|
| 2019 |
Najjar SM, Perdomo G. Hepatic Insulin Clearance: Mechanism and Physiology. Physiology (Bethesda, Md.). 34: 198-215. PMID 30968756 DOI: 10.1152/Physiol.00048.2018 |
0.573 |
|
| 2019 |
Ghadieh HE, Russo L, Muturi HT, Ghanem SS, Manaserh IH, Noh HL, Suk S, Kim JK, Hill JW, Najjar SM. Hyperinsulinemia drives hepatic insulin resistance in male mice with liver-specific Ceacam1 deletion independently of lipolysis. Metabolism: Clinical and Experimental. PMID 30664851 DOI: 10.1016/J.Metabol.2019.01.008 |
0.59 |
|
| 2019 |
Muturi H, Khuder S, Ghadieh H, Abu Helal R, Stankus H, Kim J, Najjar S. SAT-174 Loss of CEACAM1 in Endothelial Cells Causes Hepatic Fibrogenesis Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sat-174 |
0.539 |
|
| 2019 |
Ghadieh H, Russo L, Muturi H, Ghanem S, Manaserh I, Noh HL, Suk S, Kim J, Gatto-Weis C, Hill J, Najjar S. SAT-151 Hyperinsulinemia-Driven Progressive Metabolic Dysfunction in Male Mice with Liver-Specific CEACAM1 Deletion Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Sat-151 |
0.375 |
|
| 2018 |
Horst AK, Najjar SM, Wagener C, Tiegs G. CEACAM1 in Liver Injury, Metabolic and Immune Regulation. International Journal of Molecular Sciences. 19. PMID 30314283 DOI: 10.3390/Ijms19103110 |
0.467 |
|
| 2018 |
Villa-Pérez P, Merino B, Fernández-Díaz CM, Cidad P, Lobatón CD, Moreno A, Muturi HT, Ghadieh HE, Najjar SM, Leissring MA, Cózar-Castellano I, Perdomo G. Liver-specific ablation of insulin-degrading enzyme causes hepatic insulin resistance and glucose intolerance, without affecting insulin clearance in mice. Metabolism: Clinical and Experimental. PMID 30098324 DOI: 10.1016/J.Metabol.2018.08.001 |
0.559 |
|
| 2018 |
Huang L, Liu J, Zhang XO, Sibley K, Najjar SM, Lee MM, Wu JQ. Inhibition of protein arginine methyltransferase 5 enhances hepatic mitochondrial biogenesis. The Journal of Biological Chemistry. PMID 29773653 DOI: 10.1074/Jbc.Ra118.002377 |
0.361 |
|
| 2018 |
Ghadieh HE, Muturi HT, Russo L, Marino CC, Ghanem SS, Khuder SS, Hanna JC, Jash S, Puri V, Heinrich G, Gatto-Weis C, Lee KY, Najjar SM. Exenatide induces carcinoembryonic antigen-related cell adhesion molecule 1 expression to prevent hepatic steatosis. Hepatology Communications. 2: 35-47. PMID 29404511 DOI: 10.1002/hep4.1117 |
0.528 |
|
| 2018 |
Russo L, Muturi HT, Ghadieh HE, Wisniewski AM, Morgan EE, Quadri SS, Landesberg GP, Siragy HM, Vazquez G, Scalia R, Gupta R, Najjar SM. Liver-specific rescuing of CEACAM1 reverses endothelial and cardiovascular abnormalities in male mice with null deletion of Ceacam1 gene. Molecular Metabolism. PMID 29396368 DOI: 10.1016/J.Molmet.2018.01.009 |
0.532 |
|
| 2018 |
MUTURI HT, GHADIEH HE, KHUDER SS, JASH S, ABU HELAL R, DANIELS NA, LIU J, PURI V, VAZQUEZ G, GUPTA R, NAJJAR SM. Loss of CEACAM1 in Endothelial Cells Contributes to the Development of Cardiac Fibrosis Diabetes. 67: 357-OR. DOI: 10.2337/Db18-357-Or |
0.419 |
|
| 2017 |
Ghadieh HE, Muturi HT, Najjar SM. Exenatide Prevents Diet-induced Hepatocellular Injury in A CEACAM1-Dependent Mechanism. Journal of Diabetes and Treatment. 2017. PMID 29431170 |
0.447 |
|
| 2017 |
Russo L, Muturi HT, Ghadieh HE, Ghanem SS, Bowman TA, Noh HL, Dagdeviren S, Dogbey GY, Kim JK, Heinrich G, Najjar SM. Liver-specific reconstitution of CEACAM1 reverses the metabolic abnormalities caused by its global deletion in male mice. Diabetologia. PMID 28913658 DOI: 10.1007/S00125-017-4432-Y |
0.595 |
|
| 2017 |
Ghanem SS, Muturi HT, DeAngelis AM, Hu J, Kulkarni RN, Heinrich G, Najjar SM. Age-dependent insulin resistance in male mice with null deletion of the carcinoembryonic antigen-related cell adhesion molecule 2 gene. Diabetologia. PMID 28567513 DOI: 10.1007/S00125-017-4307-2 |
0.784 |
|
| 2017 |
Heinrich G, Muturi HT, Rezaei K, Al-Share QY, DeAngelis AM, Bowman TA, Ghadieh HE, Ghanem SS, Zhang D, Garofalo RS, Yin L, Najjar SM. Reduced Hepatic Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Level in Obesity. Frontiers in Endocrinology. 8: 54. PMID 28396653 DOI: 10.3389/Fendo.2017.00054 |
0.756 |
|
| 2017 |
Heinrich G, Ghadieh HE, Ghanem SS, Muturi HT, Rezaei K, Al-Share QY, Bowman TA, Zhang D, Garofalo RS, Yin L, Najjar SM. Loss of Hepatic CEACAM1: A Unifying Mechanism Linking Insulin Resistance to Obesity and Non-Alcoholic Fatty Liver Disease. Frontiers in Endocrinology. 8: 8. PMID 28184213 DOI: 10.3389/Fendo.2017.00008 |
0.556 |
|
| 2016 |
Russo L, Ghadieh HE, Ghanem SS, Al-Share QY, Smiley ZN, Gatto-Weis C, Esakov EL, McInerney MF, Heinrich G, Tong X, Yin L, Najjar SM. Role for hepatic CEACAM1 in regulating fatty acid metabolism along the adipocyte-hepatocyte axis. Journal of Lipid Research. PMID 27777319 DOI: 10.1194/Jlr.M072066 |
0.553 |
|
| 2016 |
Ramakrishnan SK, Russo L, Ghanem SS, Patel PR, Oyarce AM, Heinrich G, Najjar SM. Fenofibrate Decreases Insulin Clearance and Insulin Secretion to Maintain Insulin Sensitivity. The Journal of Biological Chemistry. PMID 27662905 DOI: 10.1074/Jbc.M116.745778 |
0.599 |
|
| 2016 |
Stechschulte LA, Qiu B, Warrier M, Hinds TD, Zhang M, Gu H, Xu Y, Khuder SS, Russo L, Najjar SM, Lecka-Czernik B, Yong W, Sanchez ER. FKBP51 Null Mice Are Resistant to Diet-Induced Obesity and the PPARγ Agonist Rosiglitazone. Endocrinology. en20151996. PMID 27442117 DOI: 10.1210/En.2015-1996 |
0.478 |
|
| 2016 |
Heinrich G, Russo L, Castaneda TR, Pfeiffer V, Ghadieh HE, Ghanem SS, Wu J, Faulkner LD, Ergün S, McInerney MF, Hill JW, Najjar SM. Leptin resistance contributes to obesity in mice with null mutation of carcinoembryonic antigen cell adhesion molecule 1. The Journal of Biological Chemistry. PMID 27002145 DOI: 10.1074/Jbc.M116.716431 |
0.529 |
|
| 2016 |
Ramakrishnan SK, Khuder SS, Al-Share QY, Russo L, Abdallah SL, Patel PR, Heinrich G, Muturi HT, Mopidevi BR, Oyarce AM, Shah YM, Sanchez ER, Najjar SM. PPAR alpha Activation Reduces Hepatic CEACAM1 Expression to Regulate Fatty Acid Oxidation during Fasting-refeeding Transition. The Journal of Biological Chemistry. PMID 26846848 DOI: 10.1074/Jbc.M116.714014 |
0.57 |
|
| 2015 |
Ghanem SS, Heinrich G, Lester SG, Pfeiffer V, Bhattacharya S, Patel PR, DeAngelis AM, Dai T, Ramakrishnan SK, Smiley ZN, Jung DY, Lee Y, Kitamura T, Ergun S, Kulkarni RN, ... ... Najjar SM, et al. Increased Glucose-induced Secretion of Glucagon-like Peptide-1 in Mice Lacking the Carcino-Embryonic Antigen-related Cell Adhesion Molecule 2. The Journal of Biological Chemistry. PMID 26586918 DOI: 10.1074/Jbc.M115.692582 |
0.832 |
|
| 2015 |
Li C, Culver SA, Quadri S, Ledford KL, Al-Share QY, Ghadieh HE, Najjar SM, Siragy HM. High-fat diet amplifies renal renin angiotensin system expression, blood pressure elevation, and renal dysfunction caused by Ceacam1 null deletion. American Journal of Physiology. Endocrinology and Metabolism. 309: E802-10. PMID 26374765 DOI: 10.1152/Ajpendo.00158.2015 |
0.449 |
|
| 2015 |
Lester SG, Russo L, Ghanem SS, Khuder SS, DeAngelis AM, Esakov EL, Bowman TA, Heinrich G, Al-Share QY, McInerney MF, Philbrick WM, Najjar SM. Hepatic CEACAM1 Over-Expression Protects Against Diet-Induced Fibrosis and Inflammation in White Adipose Tissue. Frontiers in Endocrinology. 6: 116. PMID 26284027 DOI: 10.3389/Fendo.2015.00116 |
0.775 |
|
| 2015 |
Balasubramanian P, Varde PA, Abdallah SL, Najjar SM, MohanKumar PS, MohanKumar SM. Differential effects of prenatal stress on metabolic programming in diet-induced obese and dietary-resistant rats. American Journal of Physiology. Endocrinology and Metabolism. 309: E582-8. PMID 26219866 DOI: 10.1152/Ajpendo.00167.2015 |
0.351 |
|
| 2015 |
Ghadieh HE, Smiley ZN, Kopfman MW, Najjar MG, Hake MJ, Najjar SM. Chlorogenic acid/chromium supplement rescues diet-induced insulin resistance and obesity in mice. Nutrition & Metabolism. 12: 19. PMID 26045713 DOI: 10.1186/S12986-015-0014-5 |
0.555 |
|
| 2015 |
Al-Share QY, DeAngelis AM, Lester SG, Bowman TA, Ramakrishnan SK, Abdallah SL, Russo L, Patel PR, Kaw MK, Raphael CK, Kim AJ, Heinrich G, Lee AD, Kim JK, Kulkarni RN, ... ... Najjar SM, et al. Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance. Diabetes. 64: 2780-90. PMID 25972571 DOI: 10.2337/Db14-1772 |
0.781 |
|
| 2014 |
Alshahrani MM, Yang E, Yip J, Ghanem SS, Abdallah SL, deAngelis AM, O'Malley CJ, Moheimani F, Najjar SM, Jackson DE. CEACAM2 negatively regulates hemi (ITAM-bearing) GPVI and CLEC-2 pathways and thrombus growth in vitro and in vivo. Blood. 124: 2431-41. PMID 25085348 DOI: 10.1182/Blood-2014-04-569707 |
0.686 |
|
| 2014 |
Stechschulte LA, Hinds TD, Ghanem SS, Shou W, Najjar SM, Sanchez ER. FKBP51 reciprocally regulates GRα and PPARγ activation via the Akt-p38 pathway. Molecular Endocrinology (Baltimore, Md.). 28: 1254-64. PMID 24933248 DOI: 10.1210/Me.2014-1023 |
0.356 |
|
| 2014 |
Stechschulte LA, Hinds TD, Khuder SS, Shou W, Najjar SM, Sanchez ER. FKBP51 controls cellular adipogenesis through p38 kinase-mediated phosphorylation of GRα and PPARγ. Molecular Endocrinology (Baltimore, Md.). 28: 1265-75. PMID 24933247 DOI: 10.1210/Me.2014-1022 |
0.41 |
|
| 2014 |
Pereira S, Park E, Mori Y, Haber CA, Han P, Uchida T, Stavar L, Oprescu AI, Koulajian K, Ivovic A, Yu Z, Li D, Bowman TA, Dewald J, El-Benna J, ... ... Najjar SM, et al. FFA-induced hepatic insulin resistance in vivo is mediated by PKCδ, NADPH oxidase, and oxidative stress. American Journal of Physiology. Endocrinology and Metabolism. 307: E34-46. PMID 24824652 DOI: 10.1152/Ajpendo.00436.2013 |
0.536 |
|
| 2014 |
Kim JH, Meyers MS, Khuder SS, Abdallah SL, Muturi HT, Russo L, Tate CR, Hevener AL, Najjar SM, Leloup C, Mauvais-Jarvis F. Tissue-selective estrogen complexes with bazedoxifene prevent metabolic dysfunction in female mice. Molecular Metabolism. 3: 177-90. PMID 24634829 DOI: 10.1016/J.Molmet.2013.12.009 |
0.515 |
|
| 2014 |
Ebke LA, Nestor-Kalinoski AL, Slotterbeck BD, Al-Dieri AG, Ghosh-Lester S, Russo L, Najjar SM, von Grafenstein H, McInerney MF. Tight association between macrophages and adipocytes in obesity: implications for adipocyte preparation. Obesity (Silver Spring, Md.). 22: 1246-55. PMID 24376179 DOI: 10.1002/Oby.20634 |
0.338 |
|
| 2014 |
Najjar SM, Russo L. CEACAM1 loss links inflammation to insulin resistance in obesity and non-alcoholic steatohepatitis (NASH). Seminars in Immunopathology. 36: 55-71. PMID 24258517 DOI: 10.1007/S00281-013-0407-3 |
0.426 |
|
| 2013 |
Najjar SM, Ledford KJ, Abdallah SL, Paus A, Russo L, Kaw MK, Ramakrishnan SK, Muturi HT, Raphael CK, Lester SG, Heinrich G, Pierre SV, Benndorf R, Kleff V, Jaffa AA, et al. Ceacam1 deletion causes vascular alterations in large vessels. American Journal of Physiology. Endocrinology and Metabolism. 305: E519-29. PMID 23800882 DOI: 10.1152/Ajpendo.00266.2013 |
0.484 |
|
| 2013 |
Huang J, Ledford KJ, Pitkin WB, Russo L, Najjar SM, Siragy HM. Targeted deletion of murine CEACAM 1 activates PI3K-Akt signaling and contributes to the expression of (Pro)renin receptor via CREB family and NF-κB transcription factors. Hypertension. 62: 317-23. PMID 23734002 DOI: 10.1161/Hypertensionaha.113.01324 |
0.498 |
|
| 2012 |
Friedman TC, Sinha-Hikim I, Parveen M, Najjar SM, Liu Y, Mangubat M, Shin CS, Lyzlov A, Ivey R, Shaheen M, French SW, Sinha-Hikim AP. Additive effects of nicotine and high-fat diet on hepatic steatosis in male mice. Endocrinology. 153: 5809-20. PMID 23093702 DOI: 10.1210/En.2012-1750 |
0.41 |
|
| 2012 |
Chen XY, Gu XT, Saiyin H, Wan B, Zhang YJ, Li J, Wang YL, Gao R, Wang YF, Dong WP, Najjar SM, Zhang CY, Ding HF, Liu JO, Yu L. Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic β-cells. The Journal of Biological Chemistry. 287: 30368-75. PMID 22798068 DOI: 10.1074/Jbc.M112.375618 |
0.495 |
|
| 2012 |
Gupta S, Yan Y, Malhotra D, Liu J, Xie Z, Najjar SM, Shapiro JI. Ouabain and insulin induce sodium pump endocytosis in renal epithelium. Hypertension. 59: 665-72. PMID 22311908 DOI: 10.1161/Hypertensionaha.111.176727 |
0.515 |
|
| 2012 |
Patel PR, Ramakrishnan SK, Kaw MK, Raphael CK, Ghosh S, Marino JS, Heinrich G, Lee SJ, Bourey RE, Hill JW, Jung DY, Morgan DA, Kim JK, Rahmouni K, Rahmouni SK, ... Najjar SM, et al. Increased metabolic rate and insulin sensitivity in male mice lacking the carcino-embryonic antigen-related cell adhesion molecule 2. Diabetologia. 55: 763-72. PMID 22159884 DOI: 10.1007/S00125-011-2388-X |
0.545 |
|
| 2012 |
Patel PR, Ramakrishnan SK, Kaw MK, Raphael CK, Ghosh S, Marino JS, Heinrich G, Lee SJ, Bourey RE, Hill JW, Jung DY, Morgan DA, Kim JK, Rahmouni K, Najjar SM. Erratum to: Increased metabolic rate and insulin sensitivity in male mice lacking the carcino-embryonic antigen-related cell adhesion molecule 2 Diabetologia. 55: 861-861. DOI: 10.1007/s00125-012-2453-0 |
0.421 |
|
| 2011 |
Hinds TD, Stechschulte LA, Cash HA, Whisler D, Banerjee A, Yong W, Khuder SS, Kaw MK, Shou W, Najjar SM, Sanchez ER. Protein phosphatase 5 mediates lipid metabolism through reciprocal control of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ (PPARγ). The Journal of Biological Chemistry. 286: 42911-22. PMID 21994940 DOI: 10.1074/Jbc.M111.311662 |
0.4 |
|
| 2011 |
Tiano JP, Delghingaro-Augusto V, Le May C, Liu S, Kaw MK, Khuder SS, Latour MG, Bhatt SA, Korach KS, Najjar SM, Prentki M, Mauvais-Jarvis F. Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes. The Journal of Clinical Investigation. 121: 3331-42. PMID 21747171 DOI: 10.1172/Jci44564 |
0.408 |
|
| 2011 |
Wuescher L, Angevine K, Hinds T, Ramakrishnan S, Najjar SM, Mensah-Osman EJ. Insulin regulates menin expression, cytoplasmic localization, and interaction with FOXO1. American Journal of Physiology. Endocrinology and Metabolism. 301: E474-83. PMID 21693693 DOI: 10.1152/Ajpendo.00022.2011 |
0.552 |
|
| 2010 |
Ghosh S, Kaw M, Patel PR, Ledford KJ, Bowman TA, McInerney MF, Erickson SK, Bourey RE, Najjar SM. Mice with null mutation of Ceacam I develop nonalcoholic steatohepatitis. Hepatic Medicine : Evidence and Research. 2010: 69-78. PMID 21949477 DOI: 10.2147/Hmer.S8902 |
0.551 |
|
| 2010 |
Bowman TA, Ramakrishnan SK, Kaw M, Lee SJ, Patel PR, Golla VK, Bourey RE, Haram PM, Koch LG, Britton SL, Wisløff U, Lee AD, Najjar SM. Caloric restriction reverses hepatic insulin resistance and steatosis in rats with low aerobic capacity. Endocrinology. 151: 5157-64. PMID 20861239 DOI: 10.1210/En.2010-0176 |
0.542 |
|
| 2010 |
Hinds TD, Ramakrishnan S, Cash HA, Stechschulte LA, Heinrich G, Najjar SM, Sanchez ER. Discovery of glucocorticoid receptor-beta in mice with a role in metabolism. Molecular Endocrinology (Baltimore, Md.). 24: 1715-27. PMID 20660300 DOI: 10.1210/Me.2009-0411 |
0.442 |
|
| 2010 |
Warrier M, Hinds TD, Ledford KJ, Cash HA, Patel PR, Bowman TA, Stechschulte LA, Yong W, Shou W, Najjar SM, Sanchez ER. Susceptibility to diet-induced hepatic steatosis and glucocorticoid resistance in FK506-binding protein 52-deficient mice. Endocrinology. 151: 3225-36. PMID 20427484 DOI: 10.1210/En.2009-1158 |
0.542 |
|
| 2010 |
Heinrich G, Ghosh S, Deangelis AM, Schroeder-Gloeckler JM, Patel PR, Castaneda TR, Jeffers S, Lee AD, Jung DY, Zhang Z, Opland DM, Myers MG, Kim JK, Najjar SM. Carcinoembryonic antigen-related cell adhesion molecule 2 controls energy balance and peripheral insulin action in mice. Gastroenterology. 139: 644-52, 652.e1. PMID 20381490 DOI: 10.1053/J.Gastro.2010.03.056 |
0.766 |
|
| 2010 |
Huang S, Kaw M, Harris MT, Ebraheim N, McInerney MF, Najjar SM, Lecka-Czernik B. Decreased osteoclastogenesis and high bone mass in mice with impaired insulin clearance due to liver-specific inactivation to CEACAM1. Bone. 46: 1138-45. PMID 20044046 DOI: 10.1016/J.Bone.2009.12.020 |
0.38 |
|
| 2009 |
Gayen JR, Saberi M, Schenk S, Biswas N, Vaingankar SM, Cheung WW, Najjar SM, O'Connor DT, Bandyopadhyay G, Mahata SK. A novel pathway of insulin sensitivity in chromogranin A null mice: a crucial role for pancreastatin in glucose homeostasis. The Journal of Biological Chemistry. 284: 28498-509. PMID 19706599 DOI: 10.1074/Jbc.M109.020636 |
0.592 |
|
| 2009 |
Tjønna AE, Rognmo Ø, Stølen T, Bye A, Haram PM, Loennechen JP, Slørdahl SA, Wisløff U, Lee SJ, Al-Share QY, Najjar SM, Skogvoll E, Kemi OJ. Response to Letter Regarding Article, “Aerobic Interval Training Versus Continuous Moderate Exercise as a Treatment for the Metabolic Syndrome: A Pilot Study” Circulation. 119. DOI: 10.1161/Circulationaha.108.835611 |
0.308 |
|
| 2009 |
Najjar SM, Li Calzi S, Lakkis M, Nabih ZT, Choice CV. P-54: pp 120, a specific substrate of the insulin receptor tyrosine kinase, differentially regulates internalization of two variant isoforms of the insulin receptor Experimental and Clinical Endocrinology & Diabetes. 104: 121-122. DOI: 10.1055/S-0029-1211597 |
0.517 |
|
| 2008 |
Lee SJ, Heinrich G, Fedorova L, Al-Share QY, Ledford KJ, Fernstrom MA, McInerney MF, Erickson SK, Gatto-Weis C, Najjar SM. Development of nonalcoholic steatohepatitis in insulin-resistant liver-specific S503A carcinoembryonic antigen-related cell adhesion molecule 1 mutant mice. Gastroenterology. 135: 2084-95. PMID 18848945 DOI: 10.1053/J.Gastro.2008.08.007 |
0.543 |
|
| 2008 |
DeAngelis AM, Heinrich G, Dai T, Bowman TA, Patel PR, Lee SJ, Hong EG, Jung DY, Assmann A, Kulkarni RN, Kim JK, Najjar SM. Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism. Diabetes. 57: 2296-303. PMID 18544705 DOI: 10.2337/Db08-0379 |
0.835 |
|
| 2006 |
Park SY, Cho YR, Kim HJ, Hong EG, Higashimori T, Lee SJ, Goldberg IJ, Shulman GI, Najjar SM, Kim JK. Mechanism of glucose intolerance in mice with dominant negative mutation of CEACAM1. American Journal of Physiology. Endocrinology and Metabolism. 291: E517-24. PMID 16638824 DOI: 10.1152/Ajpendo.00077.2006 |
0.607 |
|
| 2005 |
Najjar SM, Yang Y, Fernström MA, Lee SJ, Deangelis AM, Rjaily GA, Al-Share QY, Dai T, Miller TA, Ratnam S, Ruch RJ, Smith S, Lin SH, Beauchemin N, Oyarce AM. Insulin acutely decreases hepatic fatty acid synthase activity. Cell Metabolism. 2: 43-53. PMID 16054098 DOI: 10.1016/J.Cmet.2005.06.001 |
0.835 |
|
| 2004 |
McInerney MF, Najjar SM, Brickley D, Lutzke M, Abou-Rjaily GA, Reifsnyder P, Haskell BD, Flurkey K, Zhang YJ, Pietropaolo SL, Pietropaolo M, Byers JP, Leiter EH. Anti-insulin receptor autoantibodies are not required for type 2 diabetes pathogenesis in NZL/Lt mice, a New Zealand obese (NZO)-derived mouse strain. Experimental Diabesity Research. 5: 177-85. PMID 15512785 DOI: 10.1080/15438600490478029 |
0.796 |
|
| 2004 |
Abou-Rjaily GA, Lee SJ, May D, Al-Share QY, Deangelis AM, Ruch RJ, Neumaier M, Kalthoff H, Lin SH, Najjar SM. CEACAM1 modulates epidermal growth factor receptor--mediated cell proliferation. The Journal of Clinical Investigation. 114: 944-52. PMID 15467833 DOI: 10.1172/JCI21786 |
0.8 |
|
| 2004 |
Dai T, Abou-Rjaily GA, Al-Share' QY, Yang Y, Fernström MA, Deangelis AM, Lee AD, Sweetman L, Amato A, Pasquali M, Lopaschuk GD, Erickson SK, Najjar SM. Interaction between altered insulin and lipid metabolism in CEACAM1-inactive transgenic mice. The Journal of Biological Chemistry. 279: 45155-61. PMID 15316023 DOI: 10.1074/Jbc.M404764200 |
0.796 |
|
| 2004 |
Abou-Rjaily GA, Lee SJ, May D, Al-Share QY, DeAngelis AM, Ruch RJ, Neumaier M, Kalthoff H, Lin S, Najjar SM. CEACAM1 modulates epidermal growth factor receptor–mediated cell proliferation Journal of Clinical Investigation. 114: 944-952. DOI: 10.1172/Jci200421786 |
0.796 |
|
| 2002 |
Northcott CA, Poy MN, Najjar SM, Watts SW. Phosphoinositide 3-kinase mediates enhanced spontaneous and agonist-induced contraction in aorta of deoxycorticosterone acetate-salt hypertensive rats. Circulation Research. 91: 360-9. PMID 12193470 DOI: 10.1161/01.Res.0000030861.13850.F1 |
0.681 |
|
| 2002 |
Najjar SM. Regulation of insulin action by CEACAM1. Trends in Endocrinology and Metabolism: Tem. 13: 240-5. PMID 12128284 DOI: 10.1016/S1043-2760(02)00608-2 |
0.601 |
|
| 2002 |
Poy MN, Yang Y, Rezaei K, Fernström MA, Lee AD, Kido Y, Erickson SK, Najjar SM. CEACAM1 regulates insulin clearance in liver. Nature Genetics. 30: 270-6. PMID 11850617 DOI: 10.1038/Ng840 |
0.813 |
|
| 2002 |
Poy MN, Ruch RJ, Fernstrom MA, Okabayashi Y, Najjar SM. Shc and CEACAM1 interact to regulate the mitogenic action of insulin. The Journal of Biological Chemistry. 277: 1076-84. PMID 11694516 DOI: 10.1074/Jbc.M108415200 |
0.784 |
|
| 2001 |
Han E, Phan D, Lo P, Poy MN, Behringer R, Najjar SM, Lin SH. Differences in tissue-specific and embryonic expression of mouse Ceacam1 and Ceacam2 genes. The Biochemical Journal. 355: 417-23. PMID 11284729 DOI: 10.1042/0264-6021:3550417 |
0.679 |
|
| 2001 |
Najjar SM, Broyart JP, Hampp LT, Gray GM. Sucrase-alpha-dextrinase in the spontaneously diabetic BioBreed Wistar rat: altered intracellular carbohydrate processing. Journal of Cellular Biochemistry. 81: 252-61. PMID 11241665 DOI: 10.1002/1097-4644(20010501)81:2<252::Aid-Jcb1040>3.0.Co;2-X |
0.55 |
|
| 2001 |
Najjar SM, Broyart JP, Hampp LT, Gray GM. Intestinal aminooligopeptidase in diabetic BioBreed rat: altered posttranslational processing and trafficking. American Journal of Physiology. Gastrointestinal and Liver Physiology. 280: G104-12. PMID 11123203 DOI: 10.1152/Ajpgi.2001.280.1.G104 |
0.588 |
|
| 2000 |
Soni P, Lakkis M, Poy MN, Fernström MA, Najjar SM. The differential effects of pp120 (Ceacam 1) on the mitogenic action of insulin and insulin-like growth factor 1 are regulated by the nonconserved tyrosine 1316 in the insulin receptor. Molecular and Cellular Biology. 20: 3896-905. PMID 10805733 DOI: 10.1128/Mcb.20.11.3896-3905.2000 |
0.791 |
|
| 2000 |
Xie Z, Li H, Liu L, Kahn BB, Najjar SM, Shah W. Metabolic regulation of Na(+)/P(i)-cotransporter-1 gene expression in H4IIE cells. American Journal of Physiology. Endocrinology and Metabolism. 278: E648-55. PMID 10751198 DOI: 10.1152/Ajpendo.2000.278.4.E648 |
0.519 |
|
| 1999 |
Choice CV, Poy MN, Formisano P, Najjar SM. Comparison of the intracellular trafficking of two alternatively spliced isoforms of pp120, a substrate of the insulin receptor tyrosine kinase. Journal of Cellular Biochemistry. 76: 133-42. PMID 10581007 DOI: 10.1002/(Sici)1097-4644(20000101)76:1<133::Aid-Jcb13>3.0.Co;2-B |
0.74 |
|
| 1999 |
Soni P, Al-Hosaini KA, Fernström MA, Najjar SM. Cell adhesion properties and effects on receptor-mediated insulin endocytosis are independent properties of pp120, a substrate of the insulin receptor tyrosine kinase. Molecular Cell Biology Research Communications : McBrc. 1: 102-8. PMID 10356358 DOI: 10.1006/Mcbr.1999.0116 |
0.542 |
|
| 1998 |
Choice CV, Howard MJ, Poy MN, Hankin MH, Najjar SM. Insulin stimulates pp120 endocytosis in cells co-expressing insulin receptors. The Journal of Biological Chemistry. 273: 22194-200. PMID 9712832 DOI: 10.1074/Jbc.273.35.22194 |
0.792 |
|
| 1998 |
Najjar SM. pp120, a substrate of the insulin receptor tyrosine kinase, is associated with phosphatase activity. Biochemical and Biophysical Research Communications. 247: 457-61. PMID 9642150 DOI: 10.1006/Bbrc.1998.8822 |
0.481 |
|
| 1998 |
Najjar SM, Choice CV, Soni P, Whitman CM, Poy MN. Effect of pp120 on receptor-mediated insulin endocytosis is regulated by the juxtamembrane domain of the insulin receptor. The Journal of Biological Chemistry. 273: 12923-8. PMID 9582324 DOI: 10.1074/Jbc.273.21.12923 |
0.769 |
|
| 1997 |
Calzi SL, Choice CV, Najjar SM. Differential effect of pp120 on insulin endocytosis by two variant insulin receptor isoforms. American Journal of Physiology. Endocrinology and Metabolism. 273: E801-E808. PMID 29585237 DOI: 10.1152/Ajpendo.1997.273.4.E801 |
0.542 |
|
| 1997 |
Najjar SM, Blakesley VA, Li Calzi S, Kato H, LeRoith D, Choice CV. Differential phosphorylation of pp120 by insulin and insulin-like growth factor-1 receptors: role for the C-terminal domain of the beta-subunit. Biochemistry. 36: 6827-34. PMID 9184166 DOI: 10.1021/Bi962634H |
0.53 |
|
| 1996 |
Najjar SM, Boisclair YR, Nabih ZT, Philippe N, Imai Y, Suzuki Y, Suh DS, Ooi GT. Cloning and characterization of a functional promoter of the rat pp120 gene, encoding a substrate of the insulin receptor tyrosine kinase. The Journal of Biological Chemistry. 271: 8809-17. PMID 8621519 DOI: 10.1074/Jbc.271.15.8809 |
0.447 |
|
| 1995 |
Najjar SM, Philippe N, Suzuki Y, Ignacio GA, Formisano P, Accili D, Taylor SI. Insulin-stimulated phosphorylation of recombinant pp120/HA4, an endogenous substrate of the insulin receptor tyrosine kinase. Biochemistry. 34: 9341-9. PMID 7626603 DOI: 10.1021/Bi00029A009 |
0.638 |
|
| 1995 |
Formisano P, Najjar SM, Gross CN, Philippe N, Oriente F, Kern-Buell CL, Accili D, Gorden P. Receptor-mediated internalization of insulin. Potential role of pp120/HA4, a substrate of the insulin receptor kinase. The Journal of Biological Chemistry. 270: 24073-7. PMID 7592607 DOI: 10.1074/jbc.270.41.24073 |
0.467 |
|
| 1993 |
Najjar SM, Philippe N, Taylor SI, Accili D. Molecular cloning of pp120/ ecto-ATPase, an endogenous substrate of the insulin receptor kinase Advances in Experimental Medicine and Biology. 343: 169-174. PMID 8184737 DOI: 10.1007/978-1-4615-2988-0_17 |
0.658 |
|
| 1992 |
Najjar SM, Hampp LT, Rabkin R, Gray GM. Altered intestinal and renal brush border amino-oligopeptidase structure in diabetes and metabolic acidosis: normal and biobreed (BB) rats. Metabolism: Clinical and Experimental. 41: 76-84. PMID 1538646 DOI: 10.1016/0026-0495(92)90194-F |
0.582 |
|
| 1991 |
Najjar SM, Hampp LT, Rabkin R, Gray GM. Sucrase-alpha-dextrinase in diabetic BioBreed rats: reversible alteration of subunit structure. The American Journal of Physiology. 260: G275-83. PMID 1996646 DOI: 10.1152/Ajpgi.1991.260.2.G275 |
0.577 |
|
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