| Year |
Citation |
Score |
| 2023 |
Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Abbracchio MP, Abraham G, Agoulnik A, Alexander W, ... ... Kaupmann K, et al. The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. British Journal of Pharmacology. S23-S144. PMID 38123151 DOI: 10.1111/bph.16177 |
0.527 |
|
| 2021 |
Alexander SP, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Abbracchio MP, Alexander W, ... ... Kaupmann K, et al. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors. British Journal of Pharmacology. 178: S27-S156. PMID 34529832 DOI: 10.1111/bph.15538 |
0.528 |
|
| 2019 |
Haffke M, Fehlmann D, Rummel G, Boivineau J, Duckely M, Gommermann N, Cotesta S, Sirockin F, Freuler F, Littlewood-Evans A, Kaupmann K, Jaakola VP. Structural basis of species-selective antagonist binding to the succinate receptor. Nature. 574: 581-585. PMID 31645725 DOI: 10.1038/s41586-019-1663-8 |
0.386 |
|
| 2019 |
Bettler B, Bowery NG, Cryan JF, Enna SJ, Farb DH, Foestl W, Kaupmann K, Pin J. GABAB receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f26/2019.4 |
0.732 |
|
| 2019 |
Hoegenauer K, Kallen J, Jiménez-Núñez E, Strang R, Ertl P, Cooke NG, Hintermann S, Voegtle M, Betschart C, McKay DJJ, Wagner J, Ottl J, Beerli C, Billich A, Dawson J, ... Kaupmann K, et al. Structure-based and property-driven optimization of N-aryl imidazoles towards potent and selective oral ROR gamma t inhibitors. Journal of Medicinal Chemistry. 62: 10816-10832. DOI: 10.2210/Pdb6Q6M/Pdb |
0.319 |
|
| 2018 |
Carcache D, Vulpetti A, Kallen J, Mattes H, Orain D, Stringer R, Vangrevelinghe E, Wolf RM, Kaupmann K, Ottl J, Dawson King J, Cooke NG, Hoegenauer K, Billich A, Wagner J, et al. Optimizing a weakly binding fragment into a potent RORγt inverse agonist with efficacy in an in vivo inflammation model. Journal of Medicinal Chemistry. PMID 29990434 DOI: 10.1021/acs.jmedchem.8b00529 |
0.306 |
|
| 2017 |
Guendisch U, Weiss J, Ecoeur F, Riker JC, Kaupmann K, Kallen J, Hintermann S, Orain D, Dawson J, Billich A, Guntermann C. Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo. Plos One. 12: e0188391. PMID 29155882 DOI: 10.1371/journal.pone.0188391 |
0.321 |
|
| 2017 |
Kallen J, Izaac A, Be C, Arista L, Orain D, Kaupmann K, Guntermann C, Hoegenauer K, Hintermann S. Structural states of RORγt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds. Chemmedchem. PMID 28590087 DOI: 10.1002/cmdc.201700278 |
0.322 |
|
| 2017 |
Guntermann C, Piaia A, Hamel ML, Theil D, Rubic-Schneider T, Del Rio-Espinola A, Dong L, Billich A, Kaupmann K, Dawson J, Hoegenauer K, Orain D, Hintermann S, Stringer R, Patel DD, et al. Retinoic-acid-orphan-receptor-C inhibition suppresses Th17 cells and induces thymic aberrations. Jci Insight. 2: e91127. PMID 28289717 DOI: 10.1172/jci.insight.91127 |
0.304 |
|
| 2017 |
Jacobson LH, Hoyer D, Fehlmann D, Bettler B, Kaupmann K, Cryan JF. Blunted 5-HT1A receptor-mediated responses and antidepressant-like behavior in mice lacking the GABAB1a but not GABAB1b subunit isoforms. Psychopharmacology. PMID 28070618 DOI: 10.1007/S00213-016-4521-5 |
0.7 |
|
| 2015 |
Jacobson LH, Sweeney FF, Kaupmann K, O'Leary OF, Gassmann M, Bettler B, Cryan JF. Differential Roles of GABAB1 Subunit Isoforms on Locomotor Responses to Acute and Repeated Administration of Cocaine. Behavioural Brain Research. PMID 26518330 DOI: 10.1016/J.Bbr.2015.10.039 |
0.616 |
|
| 2014 |
Gee CE, Peterlik D, Neuhäuser C, Bouhelal R, Kaupmann K, Laue G, Uschold-Schmidt N, Feuerbach D, Zimmermann K, Ofner S, Cryan JF, van der Putten H, Fendt M, Vranesic I, Glatthar R, et al. Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behavior. The Journal of Biological Chemistry. 289: 10975-87. PMID 24596089 DOI: 10.1074/Jbc.M113.542654 |
0.557 |
|
| 2011 |
Hintermann S, Hurth K, Nozulak J, Tintelnot-Blomley M, Aichholz R, Blanz J, Kaupmann K, Mosbacher J. Exploring subtype selectivity and metabolic stability of a novel series of ligands for the benzodiazepine binding site of the GABAA receptor. Bioorganic & Medicinal Chemistry Letters. 21: 1523-6. PMID 21277199 DOI: 10.1016/j.bmcl.2010.12.107 |
0.523 |
|
| 2011 |
Vlachou S, Paterson NE, Guery S, Kaupmann K, Froestl W, Banerjee D, Finn MG, Markou A. Both GABA(B) receptor activation and blockade exacerbated anhedonic aspects of nicotine withdrawal in rats. European Journal of Pharmacology. 655: 52-8. PMID 21262222 DOI: 10.1016/J.Ejphar.2011.01.009 |
0.618 |
|
| 2009 |
Maccioni P, Carai MA, Kaupmann K, Guery S, Froestl W, Leite-Morris KA, Gessa GL, Colombo G. Reduction of alcohol's reinforcing and motivational properties by the positive allosteric modulator of the GABA(B) receptor, BHF177, in alcohol-preferring rats. Alcoholism, Clinical and Experimental Research. 33: 1749-56. PMID 19572981 DOI: 10.1111/j.1530-0277.2009.01012.x |
0.35 |
|
| 2009 |
Vlachou S, Guery S, Froestl W, Kaupmann K, Banerjee D, Finn M, Markou A. GABAB receptor positive modulators: Effects on nicotine self-administration and cue-induced reinstatement of nicotine-seeking behavior in rats Biochemical Pharmacology. 78: 917-918. DOI: 10.1016/J.Bcp.2009.06.075 |
0.337 |
|
| 2008 |
Tiao JY, Bradaia A, Biermann B, Kaupmann K, Metz M, Haller C, Rolink AG, Pless E, Barlow PN, Gassmann M, Bettler B. The sushi domains of secreted GABA(B1) isoforms selectively impair GABA(B) heteroreceptor function. The Journal of Biological Chemistry. 283: 31005-11. PMID 18765663 DOI: 10.1074/Jbc.M804464200 |
0.806 |
|
| 2008 |
Waldmeier PC, Kaupmann K, Urwyler S. Roles of GABAB receptor subtypes in presynaptic auto- and heteroreceptor function regulating GABA and glutamate release. Journal of Neural Transmission (Vienna, Austria : 1996). 115: 1401-11. PMID 18665320 DOI: 10.1007/s00702-008-0095-7 |
0.611 |
|
| 2008 |
Paterson NE, Vlachou S, Guery S, Kaupmann K, Froestl W, Markou A. Positive modulation of GABA(B) receptors decreased nicotine self-administration and counteracted nicotine-induced enhancement of brain reward function in rats. The Journal of Pharmacology and Experimental Therapeutics. 326: 306-14. PMID 18445779 DOI: 10.1124/jpet.108.139204 |
0.599 |
|
| 2007 |
Guery S, Floersheim P, Kaupmann K, Froestl W. Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors. Bioorganic & Medicinal Chemistry Letters. 17: 6206-11. PMID 17884493 DOI: 10.1016/j.bmcl.2007.09.023 |
0.594 |
|
| 2007 |
Liechti ME, Lhuillier L, Kaupmann K, Markou A. Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens shell are involved in behaviors relating to nicotine dependence. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9077-85. PMID 17715344 DOI: 10.1523/JNEUROSCI.1766-07.2007 |
0.778 |
|
| 2007 |
Jacobson LH, Kelly PH, Bettler B, Kaupmann K, Cryan JF. Specific roles of GABA(B(1)) receptor isoforms in cognition. Behavioural Brain Research. 181: 158-62. PMID 17498817 DOI: 10.1016/J.Bbr.2007.03.033 |
0.774 |
|
| 2007 |
Mombereau C, Lhuillier L, Kaupmann K, Cryan JF. GABAB receptor-positive modulation-induced blockade of the rewarding properties of nicotine is associated with a reduction in nucleus accumbens DeltaFosB accumulation. The Journal of Pharmacology and Experimental Therapeutics. 321: 172-7. PMID 17215447 DOI: 10.1124/jpet.106.116228 |
0.782 |
|
| 2007 |
Jacobson LH, Bettler B, Kaupmann K, Cryan JF. Behavioral evaluation of mice deficient in GABA(B(1)) receptor isoforms in tests of unconditioned anxiety. Psychopharmacology. 190: 541-53. PMID 17171558 DOI: 10.1007/S00213-006-0631-9 |
0.772 |
|
| 2007 |
Lhuillier L, Mombereau C, Cryan JF, Kaupmann K. GABA(B) receptor-positive modulation decreases selective molecular and behavioral effects of cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 388-98. PMID 16710312 DOI: 10.1038/sj.npp.1301102 |
0.817 |
|
| 2006 |
Jacobson LH, Bettler B, Kaupmann K, Cryan JF. GABAB1 receptor subunit isoforms exert a differential influence on baseline but not GABAB receptor agonist-induced changes in mice. The Journal of Pharmacology and Experimental Therapeutics. 319: 1317-26. PMID 16990508 DOI: 10.1124/Jpet.106.111971 |
0.793 |
|
| 2006 |
Dupuis DS, Relkovic D, Lhuillier L, Mosbacher J, Kaupmann K. Point mutations in the transmembrane region of GABAB2 facilitate activation by the positive modulator N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) in the absence of the GABAB1 subunit. Molecular Pharmacology. 70: 2027-36. PMID 16966477 DOI: 10.1124/mol.106.028183 |
0.848 |
|
| 2006 |
Jacobson LH, Kelly PH, Bettler B, Kaupmann K, Cryan JF. GABA(B(1)) receptor isoforms differentially mediate the acquisition and extinction of aversive taste memories. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8800-3. PMID 16928868 DOI: 10.1523/Jneurosci.2076-06.2006 |
0.796 |
|
| 2006 |
Shaban H, Humeau Y, Herry C, Cassasus G, Shigemoto R, Ciocchi S, Barbieri S, van der Putten H, Kaupmann K, Bettler B, Lüthi A. Generalization of amygdala LTP and conditioned fear in the absence of presynaptic inhibition. Nature Neuroscience. 9: 1028-35. PMID 16819521 DOI: 10.1038/Nn1732 |
0.726 |
|
| 2006 |
Vigot R, Barbieri S, Bräuner-Osborne H, Turecek R, Shigemoto R, Zhang YP, Luján R, Jacobson LH, Biermann B, Fritschy JM, Vacher CM, Müller M, Sansig G, Guetg N, Cryan JF, ... Kaupmann K, et al. Differential compartmentalization and distinct functions of GABAB receptor variants. Neuron. 50: 589-601. PMID 16701209 DOI: 10.1016/J.Neuron.2006.04.014 |
0.746 |
|
| 2006 |
Vacher CM, Gassmann M, Desrayaud S, Challet E, Bradaia A, Hoyer D, Waldmeier P, Kaupmann K, Pévet P, Bettler B. Hyperdopaminergia and altered locomotor activity in GABAB1-deficient mice. Journal of Neurochemistry. 97: 979-91. PMID 16606363 DOI: 10.1111/J.1471-4159.2006.03806.X |
0.716 |
|
| 2006 |
Jacobson L, Neijt H, Bettler B, Kaupmann K, Cryan J. Molecular dissection of the role of GABAB1 receptor isoforms 1a and 1b in anxiety-related behaviour European Neuropsychopharmacology. 16: S91-S92. DOI: 10.1016/S0924-977X(06)80108-2 |
0.671 |
|
| 2006 |
Lhuillier L, Mombereau C, Cryan J, Kaupmann K. GABAB receptor positive modulation attenuates selected molecular markers relevant to cocaine and nicotine dependence European Neuropsychopharmacology. 16: S11-S12. DOI: 10.1016/S0924-977X(06)80015-5 |
0.495 |
|
| 2006 |
Jacobson L, Neijt H, Bettler B, Kaupmann K, Cryan J. S.04.05 Molecular dissection of the role of GABAB1 receptor isoforms 1a and 1b in anxiety-related behaviour European Neuropsychopharmacology. 16: S171. DOI: 10.1016/S0924-977X(06)70032-3 |
0.667 |
|
| 2005 |
Sauter K, Grampp T, Fritschy JM, Kaupmann K, Bettler B, Mohler H, Benke D. Subtype-selective interaction with the transcription factor CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) regulates cell surface expression of GABA(B) receptors. The Journal of Biological Chemistry. 280: 33566-72. PMID 16081421 DOI: 10.1074/Jbc.M503482200 |
0.769 |
|
| 2005 |
Gassmann M, Haller C, Stoll Y, Abdel Aziz S, Biermann B, Mosbacher J, Kaupmann K, Bettler B. The RXR-type endoplasmic reticulum-retention/retrieval signal of GABAB1 requires distant spacing from the membrane to function. Molecular Pharmacology. 68: 137-44. PMID 15805225 DOI: 10.1124/Mol.104.010256 |
0.846 |
|
| 2005 |
Mombereau C, Kaupmann K, Gassmann M, Bettler B, van der Putten H, Cryan JF. Altered anxiety and depression-related behaviour in mice lacking GABAB(2) receptor subunits. Neuroreport. 16: 307-10. PMID 15706241 DOI: 10.1097/00001756-200502280-00021 |
0.671 |
|
| 2005 |
Cryan JF, Kaupmann K. Don't worry 'B' happy!: a role for GABA(B) receptors in anxiety and depression. Trends in Pharmacological Sciences. 26: 36-43. PMID 15629203 DOI: 10.1016/j.tips.2004.11.004 |
0.723 |
|
| 2005 |
Deriu D, Gassmann M, Firbank S, Ristig D, Lampert C, Mosbacher J, Froestl W, Kaupmann K, Bettler B, Grütter MG. Determination of the minimal functional ligand-binding domain of the GABAB1b receptor. The Biochemical Journal. 386: 423-31. PMID 15482257 DOI: 10.1042/Bj20040804 |
0.774 |
|
| 2005 |
Slattery D, Mombereau C, Froestl W, Markou A, Kaupmann K, Cryan J. P.2.19 GABAB receptor positive modulation as a novel therapeutic approach to drug dependence: blockade of the rewarding and psychostimulant effects of cocaine European Neuropsychopharmacology. 15: S45-S46. DOI: 10.1016/S0924-977X(05)80159-2 |
0.48 |
|
| 2004 |
Rüttimann E, Vacher CM, Gassmann M, Kaupmann K, Van der Putten H, Bettler B. Altered hippocampal expression of calbindin-D-28k and calretinin in GABA(B(1))-deficient mice. Biochemical Pharmacology. 68: 1613-20. PMID 15451404 DOI: 10.1016/J.Bcp.2004.07.019 |
0.779 |
|
| 2004 |
Mombereau C, Kaupmann K, van der Putten H, Cryan JF. Altered response to benzodiazepine anxiolytics in mice lacking GABA B(1) receptors. European Journal of Pharmacology. 497: 119-20. PMID 15321743 DOI: 10.1016/j.ejphar.2004.06.036 |
0.659 |
|
| 2004 |
Fritschy JM, Sidler C, Parpan F, Gassmann M, Kaupmann K, Bettler B, Benke D. Independent maturation of the GABA(B) receptor subunits GABA(B1) and GABA(B2) during postnatal development in rodent brain. The Journal of Comparative Neurology. 477: 235-52. PMID 15305362 DOI: 10.1002/Cne.20188 |
0.767 |
|
| 2004 |
Bettler B, Kaupmann K, Mosbacher J, Gassmann M. Molecular structure and physiological functions of GABA(B) receptors. Physiological Reviews. 84: 835-67. PMID 15269338 DOI: 10.1152/Physrev.00036.2003 |
0.774 |
|
| 2004 |
Gassmann M, Shaban H, Vigot R, Sansig G, Haller C, Barbieri S, Humeau Y, Schuler V, Müller M, Kinzel B, Klebs K, Schmutz M, Froestl W, Heid J, Kelly PH, ... ... Kaupmann K, et al. Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6086-97. PMID 15240800 DOI: 10.1523/Jneurosci.5635-03.2004 |
0.822 |
|
| 2004 |
Cryan JF, Kelly PH, Chaperon F, Gentsch C, Mombereau C, Lingenhoehl K, Froestl W, Bettler B, Kaupmann K, Spooren WP. Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines. The Journal of Pharmacology and Experimental Therapeutics. 310: 952-63. PMID 15113848 DOI: 10.1124/Jpet.104.066753 |
0.7 |
|
| 2004 |
Mombereau C, Kaupmann K, Froestl W, Sansig G, van der Putten H, Cryan JF. Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1050-62. PMID 15039762 DOI: 10.1038/sj.npp.1300413 |
0.721 |
|
| 2004 |
Urwyler S, Gjoni T, Kaupmann K, Pozza MF, Mosbacher J. Selected amino acids, dipeptides and arylalkylamine derivatives do not act as allosteric modulators at GABAB receptors. European Journal of Pharmacology. 483: 147-53. PMID 14729102 DOI: 10.1016/j.ejphar.2003.10.024 |
0.599 |
|
| 2004 |
Mombereau C, Kaupmann K, Froestl W, Van Der Putten H, Cryan J. P.2.25 GABAB receptors play a key role in the modulation of anxiety and antidepressant-related behaviour: genetic and pharmacological evidence European Neuropsychopharmacology. 14: S39-S40. DOI: 10.1016/S0924-977X(04)90048-X |
0.432 |
|
| 2004 |
Mombereau C, Kaupmann K, Froestl W, van der Putten H, Cryan J. S.07.03 GABAB receptors play a key rolein the modulation of anxiety and antidepressant-related behaviour: Genetic and pharmacological evidence European Neuropsychopharmacology. 14: S125. DOI: 10.1016/S0924-977X(04)80024-5 |
0.508 |
|
| 2003 |
Kaupmann K, Cryan JF, Wellendorph P, Mombereau C, Sansig G, Klebs K, Schmutz M, Froestl W, van der Putten H, Mosbacher J, Bräuner-Osborne H, Waldmeier P, Bettler B. Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice. The European Journal of Neuroscience. 18: 2722-30. PMID 14656321 DOI: 10.1111/J.1460-9568.2003.03013.X |
0.72 |
|
| 2003 |
Saghatelyan AK, Snapyan M, Gorissen S, Meigel I, Mosbacher J, Kaupmann K, Bettler B, Kornilov AV, Nifantiev NE, Sakanyan V, Schachner M, Dityatev A. Recognition molecule associated carbohydrate inhibits postsynaptic GABA(B) receptors: a mechanism for homeostatic regulation of GABA release in perisomatic synapses. Molecular and Cellular Neurosciences. 24: 271-82. PMID 14572452 DOI: 10.1016/S1044-7431(03)00163-5 |
0.761 |
|
| 2003 |
Urwyler S, Pozza MF, Lingenhoehl K, Mosbacher J, Lampert C, Froestl W, Koller M, Kaupmann K. N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function. The Journal of Pharmacology and Experimental Therapeutics. 307: 322-30. PMID 12954816 DOI: 10.1124/jpet.103.053074 |
0.653 |
|
| 2003 |
Pignot V, Hein AE, Barske C, Wiessner C, Walmsley AR, Kaupmann K, Mayeur H, Sommer B, Mir AK, Frentzel S. Characterization of two novel proteins, NgRH1 and NgRH2, structurally and biochemically homologous to the Nogo-66 receptor. Journal of Neurochemistry. 85: 717-28. PMID 12694398 DOI: 10.1046/J.1471-4159.2003.01710.X |
0.381 |
|
| 2003 |
Froestl W, Bettler B, Bittiger H, Heid J, Kaupmann K, Mickel SJ, Strub D. Ligands for expression cloning and isolation of GABA(B) receptors. Farmaco (Societã Chimica Italiana : 1989). 58: 173-83. PMID 12620413 DOI: 10.1016/S0924-977X(99)80094-7 |
0.682 |
|
| 2001 |
Urwyler S, Mosbacher J, Lingenhoehl K, Heid J, Hofstetter K, Froestl W, Bettler B, Kaupmann K. Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Molecular Pharmacology. 60: 963-71. PMID 11641424 DOI: 10.1124/Mol.60.5.963 |
0.766 |
|
| 2001 |
Schuler V, Lüscher C, Blanchet C, Klix N, Sansig G, Klebs K, Schmutz M, Heid J, Gentry C, Urban L, Fox A, Spooren W, Jaton AL, Vigouret J, Pozza M, ... ... Kaupmann K, et al. Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)). Neuron. 31: 47-58. PMID 11498050 DOI: 10.1016/S0896-6273(01)00345-2 |
0.855 |
|
| 2001 |
Froestl W, Bettler B, Bittiger H, Heid J, Kaupmann K, Mickel SJ, Strub D. Ligands for expression cloning and isolation of GABA(B) receptors. Farmaco (Societã Chimica Italiana : 1989). 56: 101-5. PMID 11347948 DOI: 10.1016/S0014-827X(01)01003-5 |
0.736 |
|
| 2001 |
Pagano A, Rovelli G, Mosbacher J, Lohmann T, Duthey B, Stauffer D, Ristig D, Schuler V, Meigel I, Lampert C, Stein T, Prezeau L, Blahos J, Pin J, Froestl W, ... ... Kaupmann K, et al. C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1189-202. PMID 11160389 DOI: 10.1523/Jneurosci.21-04-01189.2001 |
0.812 |
|
| 2000 |
Galvez T, Urwyler S, Prézeau L, Mosbacher J, Joly C, Malitschek B, Heid J, Brabet I, Froestl W, Bettler B, Kaupmann K, Pin JP. Ca(2+) requirement for high-affinity gamma-aminobutyric acid (GABA) binding at GABA(B) receptors: involvement of serine 269 of the GABA(B)R1 subunit. Molecular Pharmacology. 57: 419-26. PMID 10692480 DOI: 10.1124/Mol.57.3.419 |
0.731 |
|
| 1999 |
Lingenhoehl K, Brom R, Heid J, Beck P, Froestl W, Kaupmann K, Bettler B, Mosbacher J. Gamma-hydroxybutyrate is a weak agonist at recombinant GABA(B) receptors. Neuropharmacology. 38: 1667-73. PMID 10587082 DOI: 10.1016/S0028-3908(99)00131-8 |
0.758 |
|
| 1999 |
Franek M, Pagano A, Kaupmann K, Bettler B, Pin JP, Blahos J. The heteromeric GABA-B receptor recognizes G-protein alpha subunit C-termini. Neuropharmacology. 38: 1657-66. PMID 10587081 DOI: 10.1016/S0028-3908(99)00135-5 |
0.829 |
|
| 1999 |
Froestl W, Bettler B, Bittiger H, Heid J, Kaupmann K, Mickel SJ, Strub D. Ligands for the isolation of GABA(B) receptors [corrected] . Neuropharmacology. 38: 1641-6. PMID 10587079 DOI: 10.1016/S0028-3908(99)00134-3 |
0.749 |
|
| 1999 |
Marshall FH, Jones KA, Kaupmann K, Bettler B. GABAB receptors - the first 7TM heterodimers. Trends in Pharmacological Sciences. 20: 396-9. PMID 10498952 DOI: 10.1016/S0165-6147(99)01383-8 |
0.637 |
|
| 1999 |
Pfaff T, Malitschek B, Kaupmann K, Prézeau L, Pin JP, Bettler B, Karschin A. Alternative splicing generates a novel isoform of the rat metabotropic GABA(B)R1 receptor. The European Journal of Neuroscience. 11: 2874-82. PMID 10457184 DOI: 10.1046/J.1460-9568.1999.00704.X |
0.734 |
|
| 1999 |
Bischoff S, Leonhard S, Reymann N, Schuler V, Shigemoto R, Kaupmann K, Bettler B. Spatial distribution of GABA(B)R1 receptor mRNA and binding sites in the rat brain. The Journal of Comparative Neurology. 412: 1-16. PMID 10440706 DOI: 10.1002/(Sici)1096-9861(19990913)412:1>1::Aid-Cne1<3.0.Co;2-D |
0.727 |
|
| 1999 |
Malitschek B, Schweizer C, Keir M, Heid J, Froestl W, Mosbacher J, Kuhn R, Henley J, Joly C, Pin JP, Kaupmann K, Bettler B. The N-terminal domain of gamma-aminobutyric Acid(B) receptors is sufficient to specify agonist and antagonist binding. Molecular Pharmacology. 56: 448-54. PMID 10419566 DOI: 10.1124/Mol.56.2.448 |
0.736 |
|
| 1999 |
Mosbacher J, Kaupmann K, Schuler V, Ristig D, Struckmeyer K, Pfaff T, Karschin A, Pozza MF, Bettler B. Processing of GABABR1 in heterologous expression systems. Annals of the New York Academy of Sciences. 868: 689-92. PMID 10414355 DOI: 10.1111/J.1749-6632.1999.Tb11347.X |
0.483 |
|
| 1999 |
Sander T, Peters C, Kämmer G, Samochowiec J, Zirra M, Mischke D, Ziegler A, Kaupmann K, Bettler B, Epplen JT, Riess O. Association analysis of exonic variants of the gene encoding the GABAB receptor and idiopathic generalized epilepsy. American Journal of Medical Genetics. 88: 305-10. PMID 10402495 DOI: 10.1002/(Sici)1096-8628(19990820)88:4<305::Aid-Ajmg5>3.0.Co;2-X |
0.548 |
|
| 1999 |
Galvez T, Parmentier ML, Joly C, Malitschek B, Kaupmann K, Kuhn R, Bittiger H, Froestl W, Bettler B, Pin JP. Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding. The Journal of Biological Chemistry. 274: 13362-9. PMID 10224098 DOI: 10.1074/Jbc.274.19.13362 |
0.641 |
|
| 1999 |
Marshall FH, Jones KA, Kaupmann K, Bettler B. GABA(B) receptors - The first 7TM heterodimers Trends in Pharmacological Sciences. 20: 396-399. DOI: 10.1016/S0165-6147(99)01383-8 |
0.739 |
|
| 1999 |
Froestl W, Bettler B, Bittiger H, Heid J, Kaupmann K, Mickel SJ, Strub D. Erratum to “Ligands for the isolation of GABAB receptors” Neuropharmacology. 38: 1921. DOI: 10.1016/S0028-3908(99)00183-5 |
0.503 |
|
| 1998 |
Kaupmann K, Bettler B. Heteromerization of GABAB Receptors: A New Principle for G Protein-Coupled Receptors. Satellite Symposium to the 28th Annual Meeting of the Society for Neuroscience Los Angeles, CA, November 5-7, 1998. Cns Drug Reviews. 4: 376-379. PMID 29200228 DOI: 10.1111/j.1527-3458.1998.tb00077.x |
0.508 |
|
| 1998 |
Peters HC, Kämmer G, Volz A, Kaupmann K, Ziegler A, Bettler B, Epplen JT, Sander T, Riess O. Mapping, genomic structure, and polymorphisms of the human GABABR1 receptor gene: evaluation of its involvement in idiopathic generalized epilepsy. Neurogenetics. 2: 47-54. PMID 9933300 DOI: 10.1007/S100480050051 |
0.562 |
|
| 1998 |
Kaupmann K, Malitschek B, Schuler V, Heid J, Froestl W, Beck P, Mosbacher J, Bischoff S, Kulik A, Shigemoto R, Karschin A, Bettler B. GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature. 396: 683-7. PMID 9872317 DOI: 10.1038/25360 |
0.774 |
|
| 1998 |
Kaupmann K, Schuler V, Mosbacher J, Bischoff S, Bittiger H, Heid J, Froestl W, Leonhard S, Pfaff T, Karschin A, Bettler B. Human gamma-aminobutyric acid type B receptors are differentially expressed and regulate inwardly rectifying K+ channels. Proceedings of the National Academy of Sciences of the United States of America. 95: 14991-6. PMID 9844003 DOI: 10.1073/Pnas.95.25.14991 |
0.642 |
|
| 1998 |
Malitschek B, Rüegg D, Heid J, Kaupmann K, Bittiger H, Fröstl W, Bettler B, Kuhn R. Developmental changes of agonist affinity at GABABR1 receptor variants in rat brain. Molecular and Cellular Neurosciences. 12: 56-64. PMID 9770340 DOI: 10.1006/Mcne.1998.0698 |
0.662 |
|
| 1998 |
Bettler B, Kaupmann K, Bowery N. GABAB receptors: drugs meet clones. Current Opinion in Neurobiology. 8: 345-50. PMID 9687348 DOI: 10.1016/S0959-4388(98)80059-7 |
0.645 |
|
| 1998 |
Kaupmann K, Bettler B. Heteromerization of GABA(B) receptors: A new principle for G protein- coupled receptors. Satellite symposium to the 28(th) annual meeting of the society for neuroscience Los Angeles, CA, November 5-7, 1998 Cns Drug Reviews. 4: 376-379. |
0.681 |
|
| 1997 |
Kaupmann K, Huggel K, Heid J, Flor PJ, Bischoff S, Mickel SJ, McMaster G, Angst C, Bittiger H, Froestl W, Bettler B. Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors. Nature. 386: 239-46. PMID 9069281 DOI: 10.1038/386239A0 |
0.771 |
|
| 1995 |
Kaupmann K, Bruns C, Raulf F, Weber HP, Mattes H, Lübbert H. Two amino acids, located in transmembrane domains VI and VII, determine the selectivity of the peptide agonist SMS 201-995 for the SSTR2 somatostatin receptor. The Embo Journal. 14: 727-35. PMID 7882976 DOI: 10.1002/J.1460-2075.1995.Tb07051.X |
0.41 |
|
| 1995 |
Hoyer D, Pérez J, Schoeffter P, Langenegger D, Schüpbach E, Kaupmann K, Lübbert H, Bruns C, Reubi JC. Pharmacological identity between somatostatin SS-2 binding sites and SSTR-1 receptors. European Journal of Pharmacology. 289: 151-61. PMID 7781706 DOI: 10.1016/0922-4106(95)90179-5 |
0.381 |
|
| 1994 |
Pérez J, Rigo M, Kaupmann K, Bruns C, Yasuda K, Bell GI, Lübbert H, Hoyer D. Localization of somatostatin (SRIF) SSTR-1, SSTR-2 and SSTR-3 receptor mRNA in rat brain by in situ hybridization. Naunyn-Schmiedeberg's Archives of Pharmacology. 349: 145-60. PMID 8170498 DOI: 10.1007/Bf00169831 |
0.323 |
|
| 1994 |
Bruns C, Weckbecker G, Raulf F, Kaupmann K, Schoeffter P, Hoyer D, Lübbert H. Molecular pharmacology of somatostatin-receptor subtypes. Annals of the New York Academy of Sciences. 733: 138-46. PMID 7978861 DOI: 10.1111/J.1749-6632.1994.Tb17263.X |
0.431 |
|
| 1994 |
Hoyer D, Schoeffter P, Kaupmann K, Seuwen K, Langenegger D, Reubi J, Lübbert H, Bruns C. Pharmacological identity between somatostatin SS-1SS-2 sites and SSTR-2SSTR-1 receptors, respectively Neuropeptides. 26: 24. DOI: 10.1016/0143-4179(94)90193-7 |
0.406 |
|
| 1994 |
Lübbert H, Kaupmann K, Kluxen F, Raulf F, Goger C, Seuwen K, Bruns C. Brain somatostatin receptors Neuropeptides. 26: 24. DOI: 10.1016/0143-4179(94)90192-9 |
0.379 |
|
| 1994 |
Hoyer D, Bruns C, Perez J, Schoeffter P, Seuwen K, Kaupmann K, Raulf F, Lübbert H. Molecular pharmacology and biology of somatostatin (SRIF) receptors Neuropeptides. 26: 21-22. DOI: 10.1016/0143-4179(94)90184-8 |
0.42 |
|
| 1993 |
Kaupmann K, Bruns C, Hoyer D, Seuwen K, Lübbert H. Distribution and second messenger coupling of four somatostatin receptor subtypes expressed in brain. Febs Letters. 331: 53-9. PMID 8405411 DOI: 10.1016/0014-5793(93)80296-7 |
0.396 |
|
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