| Year |
Citation |
Score |
| 2018 |
Semenova S, Jin X, McClure-Begley TD, Tadman MP, Marks MJ, Markou A. Differential effects of withdrawal from intermittent and continuous nicotine exposure on reward deficit and somatic aspects of nicotine withdrawal and expression of α4β2* nAChRs in Wistar male rats. Pharmacology, Biochemistry, and Behavior. PMID 29908200 DOI: 10.1016/J.Pbb.2018.06.002 |
0.442 |
|
| 2018 |
Barnes SA, Young JW, Markou A, Adham N, Gyertyán I, Kiss B. The Effects of Cariprazine and Aripiprazole on PCP-Induced Deficits on Attention Assessed in the 5-Choice Serial Reaction Time Task. Psychopharmacology. PMID 29473089 DOI: 10.1007/S00213-018-4857-0 |
0.33 |
|
| 2017 |
Boutros N, Der-Avakian A, Kesby JP, Lee S, Markou A, Semenova S. Effects of adolescent alcohol exposure on stress-induced reward deficits, brain CRF, monoamines and glutamate in adult rats. Psychopharmacology. PMID 29181815 DOI: 10.1007/S00213-017-4789-0 |
0.302 |
|
| 2017 |
Li X, Sturchler E, Kaczanowska K, Cameron M, Finn MG, Griffin P, McDonald P, Markou A. KK-92A, a novel GABAB receptor positive allosteric modulator, attenuates nicotine self-administration and cue-induced nicotine seeking in rats. Psychopharmacology. PMID 28382542 DOI: 10.1007/S00213-017-4594-9 |
0.445 |
|
| 2017 |
Sturchler E, Li X, de Lourdes Ladino M, Kaczanowska K, Cameron M, Griffin PR, Finn MG, Markou A, McDonald P. GABAB receptor allosteric modulators exhibit pathway-dependent and species-selective activity. Pharmacology Research & Perspectives. 5: e00288. PMID 28357120 DOI: 10.1002/Prp2.288 |
0.393 |
|
| 2017 |
Higa KK, Grim A, Kamenski ME, van Enkhuizen J, Zhou X, Li K, Naviaux JC, Wang L, Naviaux RK, Geyer MA, Markou A, Young JW. Nicotine withdrawal-induced inattention is absent in alpha7 nAChR knockout mice. Psychopharmacology. PMID 28243714 DOI: 10.1007/S00213-017-4572-2 |
0.34 |
|
| 2017 |
Kesby JP, Chang A, Markou A, Semenova S. Modeling human methamphetamine use patterns in mice: chronic and binge methamphetamine exposure, reward function and neurochemistry. Addiction Biology. PMID 28224681 DOI: 10.1111/adb.12502 |
0.437 |
|
| 2016 |
Markou A, Li J, Tse K, Li X. Cue-induced nicotine-seeking behavior after withdrawal with or without extinction in rats. Addiction Biology. PMID 27894160 DOI: 10.1111/adb.12480 |
0.445 |
|
| 2016 |
Milienne-Petiot M, Kesby JP, Graves M, van Enkhuizen J, Semenova S, Minassian A, Markou A, Geyer MA, Young JW. The effects of reduced dopamine transporter function and chronic lithium on motivation, probabilistic learning, and neurochemistry in mice: Modeling bipolar mania. Neuropharmacology. PMID 27732870 DOI: 10.1016/J.Neuropharm.2016.07.030 |
0.345 |
|
| 2016 |
Kesby JP, Markou A, Semenova S. The effects of HIV-1 regulatory TAT protein expression on brain reward function, response to psychostimulants and delay-dependent memory in mice. Neuropharmacology. PMID 27316905 DOI: 10.1016/j.neuropharm.2016.06.011 |
0.343 |
|
| 2016 |
Boutros N, Der-Avakian A, Semenova S, Lee S, Markou A. Risky choice and brain CRF after adolescent ethanol vapor exposure and social stress in adulthood. Behavioural Brain Research. PMID 27217101 DOI: 10.1016/J.Bbr.2016.05.038 |
0.307 |
|
| 2016 |
Kesby JP, Markou A, Semenova S. Effects of HIV/TAT protein expression and chronic selegiline treatment on spatial memory, reversal learning and neurotransmitter levels in mice. Behavioural Brain Research. PMID 27211061 DOI: 10.1016/j.bbr.2016.05.034 |
0.332 |
|
| 2016 |
McKenna BS, Brown GG, Archibald S, Scadeng M, Bussell R, Kesby JP, Markou A, Soontornniyomkij V, Achim C, Semenova S, The Translational Methamphetamine Aids Research Center Tmarc Group. Microstructural changes to the brain of mice after methamphetamine exposure as identified with diffusion tensor imaging. Psychiatry Research. 249: 27-37. PMID 27000304 DOI: 10.1016/J.Pscychresns.2016.02.009 |
0.312 |
|
| 2016 |
Li X, D'Souza MS, Niño AM, Doherty J, Cross A, Markou A. Attenuation of nicotine-taking and nicotine-seeking behavior by the mGlu2 receptor positive allosteric modulators AZD8418 and AZD8529 in rats. Psychopharmacology. PMID 26873083 DOI: 10.1007/s00213-016-4220-2 |
0.428 |
|
| 2016 |
Der-Avakian A, Barnes SA, Markou A, Pizzagalli DA. Translational Assessment of Reward and Motivational Deficits in Psychiatric Disorders. Current Topics in Behavioral Neurosciences. PMID 26873017 DOI: 10.1007/7854_2015_5004 |
0.344 |
|
| 2015 |
Grayson B, Barnes SA, Markou A, Piercy C, Podda G, Neill JC. Postnatal Phencyclidine (PCP) as a Neurodevelopmental Animal Model of Schizophrenia Pathophysiology and Symptomatology: A Review. Current Topics in Behavioral Neurosciences. PMID 26510740 DOI: 10.1007/7854_2015_403 |
0.305 |
|
| 2015 |
Barnes SA, Pinto-Duarte A, Kappe A, Zembrzycki A, Metzler A, Mukamel EA, Lucero J, Wang X, Sejnowski TJ, Markou A, Behrens MM. Disruption of mGluR5 in parvalbumin-positive interneurons induces core features of neurodevelopmental disorders. Molecular Psychiatry. PMID 26260494 DOI: 10.1038/Mp.2015.113 |
0.318 |
|
| 2015 |
Young JW, Markou A. Translational Rodent Paradigms to Investigate Neuromechanisms Underlying Behaviors Relevant to Amotivation and Altered Reward Processing in Schizophrenia. Schizophrenia Bulletin. 41: 1024-34. PMID 26194891 DOI: 10.1093/Schbul/Sbv093 |
0.322 |
|
| 2015 |
Justinova Z, Le Foll B, Redhi GH, Markou A, Goldberg SR. Differential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on nicotine versus cocaine self-administration and relapse in squirrel monkeys. Psychopharmacology. PMID 26149611 DOI: 10.1007/s00213-015-3994-y |
0.519 |
|
| 2015 |
Hall FS, Der-Avakian A, Gould TJ, Markou A, Shoaib M, Young JW. Negative affective states and cognitive impairments in nicotine dependence. Neuroscience and Biobehavioral Reviews. PMID 26054790 DOI: 10.1016/J.Neubiorev.2015.06.004 |
0.409 |
|
| 2015 |
Chan MH, Tsai YL, Lee MY, Stoker AK, Markou A, Chen HH. The group II metabotropic glutamate receptor agonist LY379268 reduces toluene-induced enhancement of brain-stimulation reward and behavioral disturbances. Psychopharmacology. PMID 26044619 DOI: 10.1007/s00213-015-3973-3 |
0.357 |
|
| 2015 |
Li X, Markou A. Metabotropic Glutamate Receptor 7 (mGluR7) as a Target for the Treatment of Psychostimulant Dependence. Cns & Neurological Disorders Drug Targets. 14: 738-44. PMID 26022263 DOI: 10.2174/1871527314666150529145332 |
0.508 |
|
| 2015 |
Li X, Kaczanowska K, Finn MG, Markou A, Risbrough VB. The GABAB receptor positive modulator BHF177 attenuated anxiety, but not conditioned fear, in rats. Neuropharmacology. 97: 357-364. PMID 26002628 DOI: 10.1016/J.Neuropharm.2015.05.001 |
0.362 |
|
| 2015 |
Boutros N, Semenova S, Markou A. Adolescent alcohol exposure decreased sensitivity to nicotine in adult Wistar rats. Addiction Biology. PMID 25950618 DOI: 10.1111/adb.12263 |
0.413 |
|
| 2015 |
Stoker AK, Markou A. Neurobiological Bases of Cue- and Nicotine-induced Reinstatement of Nicotine Seeking: Implications for the Development of Smoking Cessation Medications. Current Topics in Behavioral Neurosciences. 24: 125-54. PMID 25638336 DOI: 10.1007/978-3-319-13482-6_5 |
0.359 |
|
| 2015 |
Stoker AK, Marks MJ, Markou A. Null mutation of the β2 nicotinic acetylcholine receptor subunit attenuates nicotine withdrawal-induced anhedonia in mice. European Journal of Pharmacology. 753: 146-50. PMID 25107281 DOI: 10.1016/j.ejphar.2014.05.062 |
0.392 |
|
| 2014 |
Pitsikas N, Markou A. The metabotropic glutamate 2/3 receptor agonist LY379268 counteracted ketamine-and apomorphine-induced performance deficits in the object recognition task, but not object location task, in rats. Neuropharmacology. 85: 27-35. PMID 24859609 DOI: 10.1016/j.neuropharm.2014.05.008 |
0.363 |
|
| 2014 |
Der-Avakian A, Mazei-Robison MS, Kesby JP, Nestler EJ, Markou A. Enduring deficits in brain reward function after chronic social defeat in rats: susceptibility, resilience, and antidepressant response. Biological Psychiatry. 76: 542-9. PMID 24576687 DOI: 10.1016/J.Biopsych.2014.01.013 |
0.35 |
|
| 2014 |
Mejia-Toiber J, Boutros N, Markou A, Semenova S. Impulsive choice and anxiety-like behavior in adult rats exposed to chronic intermittent ethanol during adolescence and adulthood. Behavioural Brain Research. 266: 19-28. PMID 24566059 DOI: 10.1016/j.bbr.2014.02.019 |
0.327 |
|
| 2014 |
Boutros N, Semenova S, Markou A. Adolescent intermittent ethanol exposure diminishes anhedonia during ethanol withdrawal in adulthood. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 856-64. PMID 24560005 DOI: 10.1016/j.euroneuro.2014.01.022 |
0.339 |
|
| 2014 |
D'Souza MS, Markou A. Differential role of N-methyl-D-aspartate receptor-mediated glutamate transmission in the nucleus accumbens shell and core in nicotine seeking in rats. The European Journal of Neuroscience. 39: 1314-22. PMID 24467279 DOI: 10.1111/ejn.12491 |
0.346 |
|
| 2014 |
Barnes SA, Der-Avakian A, Markou A. Anhedonia, avolition, and anticipatory deficits: assessments in animals with relevance to the negative symptoms of schizophrenia. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 744-58. PMID 24183826 DOI: 10.1016/J.Euroneuro.2013.10.001 |
0.317 |
|
| 2014 |
Kayir H, Semenova S, Markou A. Baseline impulsive choice predicts the effects of nicotine and nicotine withdrawal on impulsivity in rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 48: 6-13. PMID 24060391 DOI: 10.1016/J.Pnpbp.2013.09.007 |
0.703 |
|
| 2014 |
Li X, Semenova S, D'Souza MS, Stoker AK, Markou A. Involvement of glutamatergic and GABAergic systems in nicotine dependence: Implications for novel pharmacotherapies for smoking cessation. Neuropharmacology. 76: 554-65. PMID 23752091 DOI: 10.1016/j.neuropharm.2013.05.042 |
0.388 |
|
| 2014 |
Kesby JP, Hubbard DT, Markou A, Semenova S. Expression of HIV gp120 protein increases sensitivity to the rewarding properties of methamphetamine in mice. Addiction Biology. 19: 593-605. PMID 23252824 DOI: 10.1111/Adb.12023 |
0.31 |
|
| 2014 |
Stoker AK, Li X, Markou A. Metabotropic glutamate receptor 7 activation with AMN082 attenuates the reinforcing and motivational effects of nicotine in rats Drug and Alcohol Dependence. 140: e217. DOI: 10.1016/j.drugalcdep.2014.02.602 |
0.41 |
|
| 2014 |
Mejia-Toiber J, Markou A, Semenova S. Impulsive choice behavior and sensorimotor function in adult rats exposed to chronic intermittent ethanol during adolescence and adulthood Drug and Alcohol Dependence. 140: e145. DOI: 10.1016/j.drugalcdep.2014.02.410 |
0.331 |
|
| 2014 |
Li X, Kaczanowska K, Sturchler E, Southern M, Cameron M, McDonald P, Finn M, Griffin P, Markou A. KK-92A, a novel Gaba B receptor positive modulator, attenuates the rewarding effects of nicotine in rat Drug and Alcohol Dependence. 140: e122-e123. DOI: 10.1016/J.Drugalcdep.2014.02.350 |
0.372 |
|
| 2014 |
Der-Avakian A, DSouza MS, Pizzagalli D, Markou A. Bidirectional changes in reward responsiveness during nicotine withdrawal and acute nicotine administration assessed in the response bias probabilistic reward task in rats Drug and Alcohol Dependence. 140: e49. DOI: 10.1016/J.Drugalcdep.2014.02.154 |
0.428 |
|
| 2013 |
Le Cozannet R, Markou A, Kuczenski R. Extended-access, but not limited-access, methamphetamine self-administration induces behavioral and nucleus accumbens dopamine response changes in rats. The European Journal of Neuroscience. 38: 3487-95. PMID 24112125 DOI: 10.1111/Ejn.12361 |
0.413 |
|
| 2013 |
Grivas V, Markou A, Pitsikas N. The metabotropic glutamate 2/3 receptor agonist LY379268 induces anxiety-like behavior at the highest dose tested in two rat models of anxiety. European Journal of Pharmacology. 715: 105-10. PMID 23769742 DOI: 10.1016/j.ejphar.2013.05.048 |
0.367 |
|
| 2013 |
D'Souza MS, Markou A. The "stop" and "go" of nicotine dependence: role of GABA and glutamate. Cold Spring Harbor Perspectives in Medicine. 3. PMID 23732855 DOI: 10.1101/cshperspect.a012146 |
0.391 |
|
| 2013 |
Risher ML, Fleming RL, Boutros N, Semenova S, Wilson WA, Levin ED, Markou A, Swartzwelder HS, Acheson SK. Long-term effects of chronic intermittent ethanol exposure in adolescent and adult rats: radial-arm maze performance and operant food reinforced responding. Plos One. 8: e62940. PMID 23675442 DOI: 10.1371/Journal.Pone.0062940 |
0.315 |
|
| 2013 |
Stoker AK, Markou A. Unraveling the neurobiology of nicotine dependence using genetically engineered mice. Current Opinion in Neurobiology. 23: 493-9. PMID 23545467 DOI: 10.1016/j.conb.2013.02.013 |
0.377 |
|
| 2013 |
Li X, Risbrough VB, Cates-Gatto C, Kaczanowska K, Finn MG, Roberts AJ, Markou A. Comparison of the effects of the GABAB receptor positive modulator BHF177 and the GABAB receptor agonist baclofen on anxiety-like behavior, learning, and memory in mice. Neuropharmacology. 70: 156-67. PMID 23376712 DOI: 10.1016/J.Neuropharm.2013.01.018 |
0.364 |
|
| 2013 |
Ramirez-Niño AM, D'Souza MS, Markou A. N-acetylcysteine decreased nicotine self-administration and cue-induced reinstatement of nicotine seeking in rats: comparison with the effects of N-acetylcysteine on food responding and food seeking. Psychopharmacology. 225: 473-82. PMID 22903390 DOI: 10.1007/s00213-012-2837-3 |
0.456 |
|
| 2013 |
Li X, Xi ZX, Markou A. Metabotropic glutamate 7 (mGlu7) receptor: a target for medication development for the treatment of cocaine dependence. Neuropharmacology. 66: 12-23. PMID 22546614 DOI: 10.1016/J.Neuropharm.2012.04.010 |
0.481 |
|
| 2013 |
Vlachou S, Campos A, Kaczanowska K, Finn M, Markou A. B.4 - EVALUATION OF THE EFFECTS OF THE GABA-B RECEPTOR POSITIVE MODULATOR BHF177 ON NICOTINE SELF-ADMINISTRATION IN HIGH AND LOW IMPULSIVE RATS Behavioural Pharmacology. 24: e27. DOI: 10.1097/01.Fbp.0000434776.51732.71 |
0.357 |
|
| 2013 |
Stoker AK, Marks MJ, Markou A. Null mutation of the β2 nAChR subunit attenuated anhedonia induced by spontaneous and mecamylamine-precipitated nicotine withdrawal in mice Biochemical Pharmacology. 86: 1235. DOI: 10.1016/j.bcp.2013.08.057 |
0.327 |
|
| 2013 |
Amitai N, Markou A. Preclinical Animal Studies: Nicotine Biological Research On Addiction. 129-139. DOI: 10.1016/B978-0-12-398335-0.00014-5 |
0.744 |
|
| 2012 |
Chan MH, Chung SS, Stoker AK, Markou A, Chen HH. Sarcosine attenuates toluene-induced motor incoordination, memory impairment, and hypothermia but not brain stimulation reward enhancement in mice. Toxicology and Applied Pharmacology. 265: 158-65. PMID 23067721 DOI: 10.1016/j.taap.2012.10.004 |
0.355 |
|
| 2012 |
Sidique S, Dhanya RP, Sheffler DJ, Nickols HH, Yang L, Dahl R, Mangravita-Novo A, Smith LH, D'Souza MS, Semenova S, Conn PJ, Markou A, Cosford ND. Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence. Journal of Medicinal Chemistry. 55: 9434-45. PMID 23009245 DOI: 10.1021/Jm3005306 |
0.383 |
|
| 2012 |
Pitsikas N, Kaffe E, Markou A. The metabotropic glutamate 2/3 receptor antagonist LY341495 differentially affects recognition memory in rats. Behavioural Brain Research. 230: 374-9. PMID 22586715 DOI: 10.1016/j.bbr.2012.02.027 |
0.315 |
|
| 2012 |
Semenova S, Contet C, Roberts AJ, Markou A. Mice lacking the β4 subunit of the nicotinic acetylcholine receptor show memory deficits, altered anxiety- and depression-like behavior, and diminished nicotine-induced analgesia. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 14: 1346-55. PMID 22573727 DOI: 10.1093/Ntr/Nts107 |
0.785 |
|
| 2012 |
Hadamitzky M, McCunney S, Markou A, Kuczenski R. Development of stereotyped behaviors during prolonged escalation of methamphetamine self-administration in rats. Psychopharmacology. 223: 259-69. PMID 22526541 DOI: 10.1007/S00213-012-2713-1 |
0.422 |
|
| 2012 |
Der-Avakian A, Markou A. The neurobiology of anhedonia and other reward-related deficits. Trends in Neurosciences. 35: 68-77. PMID 22177980 DOI: 10.1016/J.Tins.2011.11.005 |
0.353 |
|
| 2012 |
Stoker AK, Olivier B, Markou A. Involvement of metabotropic glutamate receptor 5 in brain reward deficits associated with cocaine and nicotine withdrawal and somatic signs of nicotine withdrawal. Psychopharmacology. 221: 317-27. PMID 22147259 DOI: 10.1007/S00213-011-2578-8 |
0.495 |
|
| 2012 |
Stoker AK, Olivier B, Markou A. Role of α7- and β4-containing nicotinic acetylcholine receptors in the affective and somatic aspects of nicotine withdrawal: studies in knockout mice. Behavior Genetics. 42: 423-36. PMID 22009521 DOI: 10.1007/S10519-011-9511-0 |
0.402 |
|
| 2012 |
Markou A, Cryan JF. Stress, anxiety and depression: toward new treatment strategies. Neuropharmacology. 62: 1-2. PMID 21983630 DOI: 10.1016/j.neuropharm.2011.09.023 |
0.388 |
|
| 2012 |
D'Souza MS, Markou A. Schizophrenia and tobacco smoking comorbidity: nAChR agonists in the treatment of schizophrenia-associated cognitive deficits. Neuropharmacology. 62: 1564-73. PMID 21288470 DOI: 10.1016/j.neuropharm.2011.01.044 |
0.316 |
|
| 2012 |
Amitai N, Kuczenski R, Behrens MM, Markou A. Repeated phencyclidine administration alters glutamate release and decreases GABA markers in the prefrontal cortex of rats. Neuropharmacology. 62: 1422-31. PMID 21238466 DOI: 10.1016/J.Neuropharm.2011.01.008 |
0.742 |
|
| 2011 |
Amitai N, Markou A. Comparative effects of different test day challenges on performance in the 5-choice serial reaction time task. Behavioral Neuroscience. 125: 764-74. PMID 21942437 DOI: 10.1037/A0024722 |
0.727 |
|
| 2011 |
D'Souza MS, Markou A. Metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP) microinfusions into the nucleus accumbens shell or ventral tegmental area attenuate the reinforcing effects of nicotine in rats. Neuropharmacology. 61: 1399-405. PMID 21896278 DOI: 10.1016/j.neuropharm.2011.08.028 |
0.437 |
|
| 2011 |
D'Souza MS, Liechti ME, Ramirez-Niño AM, Kuczenski R, Markou A. The metabotropic glutamate 2/3 receptor agonist LY379268 blocked nicotine-induced increases in nucleus accumbens shell dopamine only in the presence of a nicotine-associated context in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2111-24. PMID 21654734 DOI: 10.1038/Npp.2011.103 |
0.461 |
|
| 2011 |
Stoker AK, Markou A. Withdrawal from chronic cocaine administration induces deficits in brain reward function in C57BL/6J mice. Behavioural Brain Research. 223: 176-81. PMID 21557971 DOI: 10.1016/j.bbr.2011.04.042 |
0.461 |
|
| 2011 |
Vlachou S, Paterson NE, Guery S, Kaupmann K, Froestl W, Banerjee D, Finn MG, Markou A. Both GABA(B) receptor activation and blockade exacerbated anhedonic aspects of nicotine withdrawal in rats. European Journal of Pharmacology. 655: 52-8. PMID 21262222 DOI: 10.1016/J.Ejphar.2011.01.009 |
0.371 |
|
| 2011 |
Vlachou S, Guery S, Froestl W, Banerjee D, Benedict J, Finn MG, Markou A. Repeated administration of the GABAB receptor positive modulator BHF177 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine seeking in rats. Psychopharmacology. 215: 117-28. PMID 21181127 DOI: 10.1007/S00213-010-2119-X |
0.47 |
|
| 2011 |
Dhanya RP, Sidique S, Sheffler DJ, Nickols HH, Herath A, Yang L, Dahl R, Ardecky R, Semenova S, Markou A, Conn PJ, Cosford ND. Design and synthesis of an orally active metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulator (PAM) that decreases cocaine self-administration in rats. Journal of Medicinal Chemistry. 54: 342-53. PMID 21155570 DOI: 10.1021/Jm1012165 |
0.43 |
|
| 2011 |
Hadamitzky M, Markou A, Kuczenski R. Extended access to methamphetamine self-administration affects sensorimotor gating in rats. Behavioural Brain Research. 217: 386-90. PMID 21070821 DOI: 10.1016/J.Bbr.2010.11.009 |
0.434 |
|
| 2011 |
Stoker AK, Markou A. Mice null for the metabotropic glutamate receptor 7 (mGluR7) exhibit attenuated brain reward deficits induced by cocaine and nicotine withdrawal and decreased somatic signs of nicotine withdrawal Biochemical Pharmacology. 82: 1046. DOI: 10.1016/j.bcp.2011.07.059 |
0.493 |
|
| 2011 |
Markou A, Hubbard DT, Semenova S. Impact of poor inhibitory control and atomoxetine treatment on brain reward function in response to nicotine and nicotine withdrawal in rats Biochemical Pharmacology. 82: 1046. DOI: 10.1016/J.Bcp.2011.07.058 |
0.433 |
|
| 2011 |
D'Souza MS, Markou A. N-methyl-d-aspartate receptor-mediated neurotransmission in the nucleus accumbens shell or core regulates nicotine reinforcement and nicotine-seeking behavior in rats Biochemical Pharmacology. 82: 1045. DOI: 10.1016/j.bcp.2011.07.057 |
0.411 |
|
| 2010 |
D'Souza MS, Markou A. Neural substrates of psychostimulant withdrawal-induced anhedonia. Current Topics in Behavioral Neurosciences. 3: 119-78. PMID 21161752 DOI: 10.1007/7854_2009_20 |
0.427 |
|
| 2010 |
Der-Avakian A, Markou A. Neonatal maternal separation exacerbates the reward-enhancing effect of acute amphetamine administration and the anhedonic effect of repeated social defeat in adult rats. Neuroscience. 170: 1189-98. PMID 20691770 DOI: 10.1016/J.Neuroscience.2010.08.002 |
0.387 |
|
| 2010 |
Contet C, Whisler KN, Jarrell H, Kenny PJ, Markou A. Patterns of responding differentiate intravenous nicotine self-administration from responding for a visual stimulus in C57BL/6J mice. Psychopharmacology. 212: 283-99. PMID 20668842 DOI: 10.1007/S00213-010-1950-4 |
0.811 |
|
| 2010 |
Vlachou S, Markou A. GABAB receptors in reward processes. Advances in Pharmacology (San Diego, Calif.). 58: 315-71. PMID 20655488 DOI: 10.1016/S1054-3589(10)58013-X |
0.393 |
|
| 2010 |
Semenova S, Markou A. The alpha2 adrenergic receptor antagonist idazoxan, but not the serotonin-2A receptor antagonist M100907, partially attenuated reward deficits associated with nicotine, but not amphetamine, withdrawal in rats. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 20: 731-46. PMID 20627663 DOI: 10.1016/j.euroneuro.2010.05.003 |
0.416 |
|
| 2010 |
Der-Avakian A, Markou A. Withdrawal from chronic exposure to amphetamine, but not nicotine, leads to an immediate and enduring deficit in motivated behavior without affecting social interaction in rats. Behavioural Pharmacology. 21: 359-68. PMID 20571366 DOI: 10.1097/Fbp.0B013E32833C7Cc8 |
0.427 |
|
| 2010 |
Jin X, Semenova S, Yang L, Ardecky R, Sheffler DJ, Dahl R, Conn PJ, Cosford ND, Markou A. The mGluR2 positive allosteric modulator BINA decreases cocaine self-administration and cue-induced cocaine-seeking and counteracts cocaine-induced enhancement of brain reward function in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2021-36. PMID 20555310 DOI: 10.1038/Npp.2010.82 |
0.467 |
|
| 2010 |
Semenova S, Hoyer D, Geyer MA, Markou A. Somatostatin-28 modulates prepulse inhibition of the acoustic startle response, reward processes and spontaneous locomotor activity in rats. Neuropeptides. 44: 421-9. PMID 20537385 DOI: 10.1016/J.Npep.2010.04.008 |
0.43 |
|
| 2010 |
Amitai N, Markou A. Disruption of performance in the five-choice serial reaction time task induced by administration of N-methyl-D-aspartate receptor antagonists: relevance to cognitive dysfunction in schizophrenia. Biological Psychiatry. 68: 5-16. PMID 20488434 DOI: 10.1016/J.Biopsych.2010.03.004 |
0.733 |
|
| 2010 |
Amitai N, Markou A. Effects of metabotropic glutamate receptor 2/3 agonism and antagonism on schizophrenia-like cognitive deficits induced by phencyclidine in rats. European Journal of Pharmacology. 639: 67-80. PMID 20371228 DOI: 10.1016/J.Ejphar.2009.12.040 |
0.745 |
|
| 2010 |
Chen HH, Stoker A, Markou A. The glutamatergic compounds sarcosine and N-acetylcysteine ameliorate prepulse inhibition deficits in metabotropic glutamate 5 receptor knockout mice. Psychopharmacology. 209: 343-50. PMID 20217053 DOI: 10.1007/s00213-010-1802-2 |
0.304 |
|
| 2009 |
Knackstedt LA, LaRowe S, Mardikian P, Malcolm R, Upadhyaya H, Hedden S, Markou A, Kalivas PW. The role of cystine-glutamate exchange in nicotine dependence in rats and humans. Biological Psychiatry. 65: 841-5. PMID 19103434 DOI: 10.1016/J.Biopsych.2008.10.040 |
0.43 |
|
| 2009 |
Markou A. Accruing preclinical evidence about metabotropic glutamate 5 receptor antagonists as treatments for drug dependence highlights the irreplaceable contributions of animal studies to the discovery of new medications for human disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 817-9. PMID 19092781 DOI: 10.1038/npp.2008.218 |
0.34 |
|
| 2009 |
Amitai N, Semenova S, Markou A. Clozapine attenuates disruptions in response inhibition and task efficiency induced by repeated phencyclidine administration in the intracranial self-stimulation procedure. European Journal of Pharmacology. 602: 78-84. PMID 19026629 DOI: 10.1016/J.Ejphar.2008.11.001 |
0.772 |
|
| 2009 |
Markou A, Chiamulera C, Geyer MA, Tricklebank M, Steckler T. Removing obstacles in neuroscience drug discovery: the future path for animal models. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 74-89. PMID 18830240 DOI: 10.1038/npp.2008.173 |
0.312 |
|
| 2009 |
Amitai N, Markou A. Increased impulsivity and disrupted attention induced by repeated phencyclidine are not attenuated by chronic quetiapine treatment. Pharmacology, Biochemistry, and Behavior. 93: 248-57. PMID 18809428 DOI: 10.1016/J.Pbb.2008.08.025 |
0.754 |
|
| 2009 |
Amitai N, Markou A. Chronic nicotine improves cognitive performance in a test of attention but does not attenuate cognitive disruption induced by repeated phencyclidine administration. Psychopharmacology. 202: 275-86. PMID 18618099 DOI: 10.1007/S00213-008-1246-0 |
0.771 |
|
| 2009 |
Kenny PJ, Chartoff E, Roberto M, Carlezon WA, Markou A. NMDA receptors regulate nicotine-enhanced brain reward function and intravenous nicotine self-administration: role of the ventral tegmental area and central nucleus of the amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 266-81. PMID 18418357 DOI: 10.1038/Npp.2008.58 |
0.65 |
|
| 2009 |
Markou A. S.09.05 Modulators of glutamate transmission for the treatment of nicotine and cocaine dependence European Neuropsychopharmacology. 19: S192-S193. DOI: 10.1016/S0924-977X(09)70236-6 |
0.307 |
|
| 2009 |
Vlachou S, Guery S, Froestl W, Kaupmann K, Banerjee D, Finn M, Markou A. GABAB receptor positive modulators: Effects on nicotine self-administration and cue-induced reinstatement of nicotine-seeking behavior in rats Biochemical Pharmacology. 78: 917-918. DOI: 10.1016/J.Bcp.2009.06.075 |
0.462 |
|
| 2009 |
D'Souza M, Liechti M, Ramirez A, Kuczenski R, Markou A. An mGlu2/3 receptor agonist blocks increases in nucleus accumbens shell dopamine induced by self-administered, but not experimenter-administered, nicotine in rats Biochemical Pharmacology. 78: 917. DOI: 10.1016/J.Bcp.2009.06.074 |
0.438 |
|
| 2008 |
Liechti ME, Markou A. Role of the glutamatergic system in nicotine dependence : implications for the discovery and development of new pharmacological smoking cessation therapies. Cns Drugs. 22: 705-24. PMID 18698872 DOI: 10.2165/00023210-200822090-00001 |
0.391 |
|
| 2008 |
Markou A. Review. Neurobiology of nicotine dependence. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 363: 3159-68. PMID 18640919 DOI: 10.1098/rstb.2008.0095 |
0.425 |
|
| 2008 |
Paterson NE, Balfour DJ, Markou A. Chronic bupropion differentially alters the reinforcing, reward-enhancing and conditioned motivational properties of nicotine in rats. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 10: 995-1008. PMID 18584463 DOI: 10.1080/14622200802097571 |
0.469 |
|
| 2008 |
Stoker AK, Semenova S, Markou A. Affective and somatic aspects of spontaneous and precipitated nicotine withdrawal in C57BL/6J and BALB/cByJ mice. Neuropharmacology. 54: 1223-32. PMID 18452957 DOI: 10.1016/j.neuropharm.2008.03.013 |
0.43 |
|
| 2008 |
Paterson NE, Vlachou S, Guery S, Kaupmann K, Froestl W, Markou A. Positive modulation of GABA(B) receptors decreased nicotine self-administration and counteracted nicotine-induced enhancement of brain reward function in rats. The Journal of Pharmacology and Experimental Therapeutics. 326: 306-14. PMID 18445779 DOI: 10.1124/jpet.108.139204 |
0.42 |
|
| 2008 |
Paterson NE, Semenova S, Markou A. The effects of chronic versus acute desipramine on nicotine withdrawal and nicotine self-administration in the rat. Psychopharmacology. 198: 351-62. PMID 18438738 DOI: 10.1007/s00213-008-1144-5 |
0.457 |
|
| 2008 |
Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, ... ... Markou A, et al. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biological Psychiatry. 63: 725-7. PMID 18371494 DOI: 10.1016/J.Biopsych.2008.03.005 |
0.477 |
|
| 2008 |
Jonkman S, Risbrough VB, Geyer MA, Markou A. Spontaneous nicotine withdrawal potentiates the effects of stress in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2131-8. PMID 18033237 DOI: 10.1038/Sj.Npp.1301607 |
0.708 |
|
| 2008 |
Liechti M, Kuczenski R, Markou A. P.2.24 Glutamate and the reinforcing effects of nicotine European Neuropsychopharmacology. 18: s56. DOI: 10.1016/S0924-977X(08)70065-8 |
0.354 |
|
| 2007 |
Liechti ME, Lhuillier L, Kaupmann K, Markou A. Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens shell are involved in behaviors relating to nicotine dependence. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9077-85. PMID 17715344 DOI: 10.1523/JNEUROSCI.1766-07.2007 |
0.486 |
|
| 2007 |
Liechti ME, Markou A. Metabotropic glutamate 2/3 receptor activation induced reward deficits but did not aggravate brain reward deficits associated with spontaneous nicotine withdrawal in rats. Biochemical Pharmacology. 74: 1299-307. PMID 17601493 DOI: 10.1016/j.bcp.2007.05.020 |
0.501 |
|
| 2007 |
Semenova S, Stolerman IP, Markou A. Chronic nicotine administration improves attention while nicotine withdrawal induces performance deficits in the 5-choice serial reaction time task in rats. Pharmacology, Biochemistry, and Behavior. 87: 360-8. PMID 17582477 DOI: 10.1016/J.Pbb.2007.05.009 |
0.43 |
|
| 2007 |
Paterson NE, Balfour DJ, Markou A. Chronic bupropion attenuated the anhedonic component of nicotine withdrawal in rats via inhibition of dopamine reuptake in the nucleus accumbens shell. The European Journal of Neuroscience. 25: 3099-108. PMID 17561823 DOI: 10.1111/j.1460-9568.2007.05546.x |
0.478 |
|
| 2007 |
Amitai N, Semenova S, Markou A. Cognitive-disruptive effects of the psychotomimetic phencyclidine and attenuation by atypical antipsychotic medications in rats. Psychopharmacology. 193: 521-37. PMID 17497138 DOI: 10.1007/S00213-007-0808-X |
0.757 |
|
| 2007 |
Paterson NE, Markou A. Animal models and treatments for addiction and depression co-morbidity. Neurotoxicity Research. 11: 1-32. PMID 17449445 DOI: 10.1007/BF03033479 |
0.319 |
|
| 2007 |
Markou A. The role of metabotropic glutamate receptors in drug reward, motivation and dependence. Drug News & Perspectives. 20: 103-8. PMID 17440633 DOI: 10.1358/dnp.2007.20.2.1083435 |
0.44 |
|
| 2007 |
Barr AM, Fish KN, Markou A. The reelin receptors VLDLR and ApoER2 regulate sensorimotor gating in mice. Neuropharmacology. 52: 1114-23. PMID 17261317 DOI: 10.1016/J.Neuropharm.2006.11.011 |
0.323 |
|
| 2007 |
Slattery DA, Markou A, Cryan JF. Evaluation of reward processes in an animal model of depression. Psychopharmacology. 190: 555-68. PMID 17177055 DOI: 10.1007/s00213-006-0630-x |
0.728 |
|
| 2007 |
Semenova S, Markou A. The effects of the mGluR5 antagonist MPEP and the mGluR2/3 antagonist LY341495 on rats' performance in the 5-choice serial reaction time task. Neuropharmacology. 52: 863-72. PMID 17126859 DOI: 10.1016/j.neuropharm.2006.10.003 |
0.327 |
|
| 2007 |
Liechti ME, Markou A. Interactive effects of the mGlu5 receptor antagonist MPEP and the mGlu2/3 receptor antagonist LY341495 on nicotine self-administration and reward deficits associated with nicotine withdrawal in rats. European Journal of Pharmacology. 554: 164-74. PMID 17113075 DOI: 10.1016/j.ejphar.2006.10.011 |
0.482 |
|
| 2007 |
O'Dell LE, Chen SA, Smith RT, Specio SE, Balster RL, Paterson NE, Markou A, Zorrilla EP, Koob GF. Extended access to nicotine self-administration leads to dependence: Circadian measures, withdrawal measures, and extinction behavior in rats. The Journal of Pharmacology and Experimental Therapeutics. 320: 180-93. PMID 17050784 DOI: 10.1124/Jpet.106.105270 |
0.775 |
|
| 2007 |
Matta SG, Balfour DJ, Benowitz NL, Boyd RT, Buccafusco JJ, Caggiula AR, Craig CR, Collins AC, Damaj MI, Donny EC, Gardiner PS, Grady SR, Heberlein U, Leonard SS, Levin ED, ... ... Markou A, et al. Guidelines on nicotine dose selection for in vivo research. Psychopharmacology. 190: 269-319. PMID 16896961 DOI: 10.1007/S00213-006-0441-0 |
0.4 |
|
| 2007 |
Markou A. Metabotropic glutamate receptor antagonists: novel therapeutics for nicotine dependence and depression? Biological Psychiatry. 61: 17-22. PMID 16876138 DOI: 10.1016/j.biopsych.2006.03.053 |
0.396 |
|
| 2006 |
Takamatsu Y, Yamamoto H, Ogai Y, Hagino Y, Markou A, Ikeda K. Fluoxetine as a potential pharmacotherapy for methamphetamine dependence: studies in mice. Annals of the New York Academy of Sciences. 1074: 295-302. PMID 17105925 DOI: 10.1196/annals.1369.026 |
0.407 |
|
| 2006 |
Henry B, Vale W, Markou A. The effect of lateral septum corticotropin-releasing factor receptor 2 activation on anxiety is modulated by stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9142-52. PMID 16957071 DOI: 10.1523/Jneurosci.1494-06.2006 |
0.333 |
|
| 2006 |
Barr AM, Powell SB, Markou A, Geyer MA. Iloperidone reduces sensorimotor gating deficits in pharmacological models, but not a developmental model, of disrupted prepulse inhibition in rats. Neuropharmacology. 51: 457-65. PMID 16762376 DOI: 10.1016/J.Neuropharm.2006.04.004 |
0.388 |
|
| 2006 |
Kenny PJ, Chen SA, Kitamura O, Markou A, Koob GF. Conditioned withdrawal drives heroin consumption and decreases reward sensitivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5894-900. PMID 16738231 DOI: 10.1523/JNEUROSCI.0740-06.2006 |
0.771 |
|
| 2006 |
O'Dell LE, Bruijnzeel AW, Smith RT, Parsons LH, Merves ML, Goldberger BA, Richardson HN, Koob GF, Markou A. Diminished nicotine withdrawal in adolescent rats: implications for vulnerability to addiction. Psychopharmacology. 186: 612-9. PMID 16598454 DOI: 10.1007/S00213-006-0383-6 |
0.708 |
|
| 2006 |
Jonkman S, Markou A. Blockade of nicotinic acetylcholine or dopamine D1-like receptors in the central nucleus of the amygdala or the bed nucleus of the stria terminalis does not precipitate nicotine withdrawal in nicotine-dependent rats. Neuroscience Letters. 400: 140-5. PMID 16563623 DOI: 10.1016/J.Neulet.2006.02.030 |
0.713 |
|
| 2006 |
Kenny PJ, Markou A. Nicotine self-administration acutely activates brain reward systems and induces a long-lasting increase in reward sensitivity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1203-11. PMID 16192981 DOI: 10.1038/sj.npp.1300905 |
0.651 |
|
| 2006 |
Slattery D, Markou A, Cryan J. P.2.b.016 Evaluation of reward processes in an animal model of depression European Neuropsychopharmacology. 16: S310. DOI: 10.1016/S0924-977X(06)70330-3 |
0.654 |
|
| 2006 |
Markou A. Pathways and systems involved in nicotine dependence Novartis Foundation Symposium. 275: 132-145. |
0.36 |
|
| 2005 |
Boutrel B, Kenny PJ, Specio SE, Martin-Fardon R, Markou A, Koob GF, de Lecea L. Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior. Proceedings of the National Academy of Sciences of the United States of America. 102: 19168-73. PMID 16357203 DOI: 10.1073/Pnas.0507480102 |
0.816 |
|
| 2005 |
Lindblom N, de Villiers SH, Semenova S, Kalayanov G, Gordon S, Schilström B, Johansson AM, Markou A, Svensson TH. Active immunisation against nicotine blocks the reward facilitating effects of nicotine and partially prevents nicotine withdrawal in the rat as measured by dopamine output in the nucleus accumbens, brain reward thresholds and somatic signs. Naunyn-Schmiedeberg's Archives of Pharmacology. 372: 182-94. PMID 16292514 DOI: 10.1007/s00210-005-0019-0 |
0.461 |
|
| 2005 |
Bruijnzeel AW, Markou A. Decreased sensitivity to the effects of dopamine D1-like, but not D2-like, receptor antagonism in the posterior hypothalamic region/anterior ventral tegmental area on brain reward function during chronic exposure to nicotine in rats. Brain Research. 1058: 91-100. PMID 16126181 DOI: 10.1016/j.brainres.2005.07.056 |
0.483 |
|
| 2005 |
Bespalov AY, Dravolina OA, Sukhanov I, Zakharova E, Blokhina E, Zvartau E, Danysz W, van Heeke G, Markou A. Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats. Neuropharmacology. 49: 167-78. PMID 16023685 DOI: 10.1016/j.neuropharm.2005.06.007 |
0.483 |
|
| 2005 |
Paterson NE, Bruijnzeel AW, Kenny PJ, Wright CD, Froestl W, Markou A. Prolonged nicotine exposure does not alter GABA(B) receptor-mediated regulation of brain reward function. Neuropharmacology. 49: 953-62. PMID 16005474 DOI: 10.1016/j.neuropharm.2005.04.031 |
0.627 |
|
| 2005 |
Kenny PJ, Markou A. Conditioned nicotine withdrawal profoundly decreases the activity of brain reward systems. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6208-12. PMID 15987950 DOI: 10.1523/JNEUROSCI.4785-04.2005 |
0.652 |
|
| 2005 |
Jonkman S, Henry B, Semenova S, Markou A. Mild anxiogenic effects of nicotine withdrawal in mice. European Journal of Pharmacology. 516: 40-5. PMID 15922326 DOI: 10.1016/J.Ejphar.2005.04.032 |
0.688 |
|
| 2005 |
Barr AM, Markou A. Psychostimulant withdrawal as an inducing condition in animal models of depression. Neuroscience and Biobehavioral Reviews. 29: 675-706. PMID 15893821 DOI: 10.1016/J.Neubiorev.2005.03.012 |
0.362 |
|
| 2005 |
Slattery DA, Markou A, Froestl W, Cryan JF. The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine: intracranial self-stimulation studies in the rat. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 2065-72. PMID 15841108 DOI: 10.1038/sj.npp.1300734 |
0.732 |
|
| 2005 |
Paterson NE, Markou A. The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats. Psychopharmacology. 179: 255-61. PMID 15619120 DOI: 10.1007/s00213-004-2070-9 |
0.505 |
|
| 2005 |
Kenny PJ, Boutrel B, Gasparini F, Koob GF, Markou A. Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats. Psychopharmacology. 179: 247-54. PMID 15602687 DOI: 10.1007/S00213-004-2069-2 |
0.82 |
|
| 2005 |
Markou A, Harrison AA, Chevrette J, Hoyer D. Paroxetine combined with a 5-HT(1A) receptor antagonist reversed reward deficits observed during amphetamine withdrawal in rats. Psychopharmacology. 178: 133-42. PMID 15452682 DOI: 10.1007/S00213-004-2008-2 |
0.483 |
|
| 2005 |
Paterson NE, Froestl W, Markou A. Repeated administration of the GABAB receptor agonist CGP44532 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine-seeking in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 119-28. PMID 15266350 DOI: 10.1038/sj.npp.1300524 |
0.498 |
|
| 2005 |
Boutrel B, Kenny P, Specio S, Winsky-Sommerer R, Halfon O, Magistretti P, Markou A, Koob G, de Lecea L. A116 A KEY ROLE FOR HYPOCRETIN IN REGULATING BRAIN REWARD FUNCTION AND REINSTATEMENT FOR DRUG-SEEKING BEHAVIOR IN RATS Behavioural Pharmacology. 16: S60. DOI: 10.1097/00008877-200509001-00189 |
0.782 |
|
| 2005 |
Slattery D, Mombereau C, Froestl W, Markou A, Kaupmann K, Cryan J. P.2.19 GABAB receptor positive modulation as a novel therapeutic approach to drug dependence: blockade of the rewarding and psychostimulant effects of cocaine European Neuropsychopharmacology. 15: S45-S46. DOI: 10.1016/S0924-977X(05)80159-2 |
0.814 |
|
| 2005 |
Boutrel B, Kenny PJ, Markou A, Koob GF. Hypocretin and brain reward function Hypocretins: Integrators of Physiological Functions. 317-326. DOI: 10.1007/0-387-25446-3_21 |
0.762 |
|
| 2004 |
Markou A, Paterson NE, Semenova S. Role of gamma-aminobutyric acid (GABA) and metabotropic glutamate receptors in nicotine reinforcement: potential pharmacotherapies for smoking cessation. Annals of the New York Academy of Sciences. 1025: 491-503. PMID 15542754 DOI: 10.1196/annals.1316.061 |
0.447 |
|
| 2004 |
Bruijnzeel AW, Markou A. Adaptations in cholinergic transmission in the ventral tegmental area associated with the affective signs of nicotine withdrawal in rats. Neuropharmacology. 47: 572-9. PMID 15380374 DOI: 10.1016/j.neuropharm.2004.05.005 |
0.493 |
|
| 2004 |
O'Dell LE, Bruijnzeel AW, Ghozland S, Markou A, Koob GF. Nicotine withdrawal in adolescent and adult rats. Annals of the New York Academy of Sciences. 1021: 167-74. PMID 15251887 DOI: 10.1196/Annals.1308.022 |
0.598 |
|
| 2004 |
Kenny PJ, Markou A. The ups and downs of addiction: role of metabotropic glutamate receptors. Trends in Pharmacological Sciences. 25: 265-72. PMID 15120493 DOI: 10.1016/j.tips.2004.03.009 |
0.614 |
|
| 2004 |
Koob GF, Ahmed SH, Boutrel B, Chen SA, Kenny PJ, Markou A, O'Dell LE, Parsons LH, Sanna PP. Neurobiological mechanisms in the transition from drug use to drug dependence. Neuroscience and Biobehavioral Reviews. 27: 739-49. PMID 15019424 DOI: 10.1016/J.Neubiorev.2003.11.007 |
0.79 |
|
| 2004 |
Spielewoy C, Markou A. Strain-specificity in nicotine attenuation of phencyclidine-induced disruption of prepulse inhibition in mice: relevance to smoking in schizophrenia patients. Behavior Genetics. 34: 343-54. PMID 14990873 DOI: 10.1023/B:BEGE.0000017878.75206.fd |
0.36 |
|
| 2004 |
Paterson NE, Markou A. Prolonged nicotine dependence associated with extended access to nicotine self-administration in rats. Psychopharmacology. 173: 64-72. PMID 14712336 DOI: 10.1007/s00213-003-1692-7 |
0.411 |
|
| 2004 |
Paterson NE, Froestl W, Markou A. The GABAB receptor agonists baclofen and CGP44532 decreased nicotine self-administration in the rat. Psychopharmacology. 172: 179-86. PMID 14610636 DOI: 10.1007/s00213-003-1637-1 |
0.443 |
|
| 2003 |
Cryan JF, Gasparini F, van Heeke G, Markou A. Non-nicotinic neuropharmacological strategies for nicotine dependence: beyond bupropion. Drug Discovery Today. 8: 1025-34. PMID 14690633 DOI: 10.1016/S1359-6446(03)02890-3 |
0.538 |
|
| 2003 |
Kenny PJ, Paterson NE, Boutrel B, Semenova S, Harrison AA, Gasparini F, Koob GF, Skoubis PD, Markou A. Metabotropic glutamate 5 receptor antagonist MPEP decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats. Annals of the New York Academy of Sciences. 1003: 415-8. PMID 14684476 DOI: 10.1196/Annals.1300.040 |
0.832 |
|
| 2003 |
Semenova S, Markou A. Clozapine treatment attenuated somatic and affective signs of nicotine and amphetamine withdrawal in subsets of rats exhibiting hyposensitivity to the initial effects of clozapine. Biological Psychiatry. 54: 1249-64. PMID 14643093 DOI: 10.1016/S0006-3223(03)00240-3 |
0.474 |
|
| 2003 |
Paterson NE, Markou A. Increased motivation for self-administered cocaine after escalated cocaine intake. Neuroreport. 14: 2229-32. PMID 14625453 DOI: 10.1097/01.wnr.0000091685.94870.ba |
0.419 |
|
| 2003 |
Kenny PJ, Koob GF, Markou A. Conditioned facilitation of brain reward function after repeated cocaine administration. Behavioral Neuroscience. 117: 1103-7. PMID 14570559 DOI: 10.1037/0735-7044.117.5.1103 |
0.728 |
|
| 2003 |
Sukhotina IA, Malyshkin AA, Markou A, Bespalov AY. Lack of depression-like effects of saccharin deprivation in rats: forced swim test, differential reinforcement of low rates and intracranial self-stimulation procedures. Behavioral Neuroscience. 117: 970-7. PMID 14570547 DOI: 10.1037/0735-7044.117.5.970 |
0.383 |
|
| 2003 |
Bruijnzeel AW, Markou A. Characterization of the effects of bupropion on the reinforcing properties of nicotine and food in rats. Synapse (New York, N.Y.). 50: 20-8. PMID 12872290 DOI: 10.1002/syn.10242 |
0.433 |
|
| 2003 |
Semenova S, Bespalov A, Markou A. Decreased prepulse inhibition during nicotine withdrawal in DBA/2J mice is reversed by nicotine self-administration. European Journal of Pharmacology. 472: 99-110. PMID 12860478 DOI: 10.1016/S0014-2999(03)01904-6 |
0.434 |
|
| 2003 |
Cryan JF, Hoyer D, Markou A. Withdrawal from chronic amphetamine induces depressive-like behavioral effects in rodents. Biological Psychiatry. 54: 49-58. PMID 12842308 DOI: 10.1016/S0006-3223(02)01730-4 |
0.55 |
|
| 2003 |
Kenny PJ, Gasparini F, Markou A. Group II metabotropic and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA)/kainate glutamate receptors regulate the deficit in brain reward function associated with nicotine withdrawal in rats. The Journal of Pharmacology and Experimental Therapeutics. 306: 1068-76. PMID 12805481 DOI: 10.1124/jpet.103.052027 |
0.635 |
|
| 2003 |
Skjei KL, Markou A. Effects of repeated withdrawal episodes, nicotine dose, and duration of nicotine exposure on the severity and duration of nicotine withdrawal in rats. Psychopharmacology. 168: 280-92. PMID 12712232 DOI: 10.1007/s00213-003-1414-1 |
0.43 |
|
| 2003 |
Spielewoy C, Markou A. Withdrawal from chronic phencyclidine treatment induces long-lasting depression in brain reward function. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1106-16. PMID 12700700 DOI: 10.1038/sj.npp.1300124 |
0.428 |
|
| 2003 |
Cryan JF, Bruijnzeel AW, Skjei KL, Markou A. Bupropion enhances brain reward function and reverses the affective and somatic aspects of nicotine withdrawal in the rat. Psychopharmacology. 168: 347-58. PMID 12698231 DOI: 10.1007/s00213-003-1445-7 |
0.593 |
|
| 2003 |
Paterson NE, Semenova S, Gasparini F, Markou A. The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice. Psychopharmacology. 167: 257-64. PMID 12682710 DOI: 10.1007/s00213-003-1432-z |
0.491 |
|
| 2003 |
Kenny PJ, Polis I, Koob GF, Markou A. Low dose cocaine self-administration transiently increases but high dose cocaine persistently decreases brain reward function in rats. The European Journal of Neuroscience. 17: 191-5. PMID 12534985 DOI: 10.1046/j.1460-9568.2003.02443.x |
0.732 |
|
| 2003 |
Semenova S, Markou A. Cocaine-seeking behavior after extended cocaine-free periods in rats: role of conditioned stimuli. Psychopharmacology. 168: 192-200. PMID 12402103 DOI: 10.1007/s00213-002-1251-7 |
0.432 |
|
| 2002 |
Markou A, Kenny PJ. Neuroadaptations to chronic exposure to drugs of abuse: relevance to depressive symptomatology seen across psychiatric diagnostic categories. Neurotoxicity Research. 4: 297-313. PMID 12829420 DOI: 10.1080/10298420290023963 |
0.576 |
|
| 2002 |
Henry SA, Lehmann-Masten V, Gasparini F, Geyer MA, Markou A. The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity. Neuropharmacology. 43: 1199-209. PMID 12527469 DOI: 10.1016/S0028-3908(02)00332-5 |
0.342 |
|
| 2002 |
Lin D, Bruijnzeel AW, Schmidt P, Markou A. Exposure to chronic mild stress alters thresholds for lateral hypothalamic stimulation reward and subsequent responsiveness to amphetamine. Neuroscience. 114: 925-33. PMID 12379248 DOI: 10.1016/S0306-4522(02)00366-4 |
0.41 |
|
| 2002 |
Zorrilla EP, Valdez GR, Nozulak J, Koob GF, Markou A. Effects of antalarmin, a CRF type 1 receptor antagonist, on anxiety-like behavior and motor activation in the rat. Brain Research. 952: 188-99. PMID 12376179 DOI: 10.1016/S0006-8993(02)03189-X |
0.698 |
|
| 2002 |
Barr AM, Markou A, Phillips AG. A 'crash' course on psychostimulant withdrawal as a model of depression. Trends in Pharmacological Sciences. 23: 475-82. PMID 12368072 DOI: 10.1016/S0165-6147(02)02086-2 |
0.382 |
|
| 2002 |
Ahmed SH, Kenny PJ, Koob GF, Markou A. Neurobiological evidence for hedonic allostasis associated with escalating cocaine use. Nature Neuroscience. 5: 625-6. PMID 12055635 DOI: 10.1038/nn872 |
0.808 |
|
| 2002 |
Cryan JF, Markou A, Lucki I. Assessing antidepressant activity in rodents: recent developments and future needs. Trends in Pharmacological Sciences. 23: 238-45. PMID 12008002 DOI: 10.1016/S0165-6147(02)02017-5 |
0.607 |
|
| 2002 |
Paterson NE, Markou A. Increased GABA neurotransmission via administration of gamma-vinyl GABA decreased nicotine self-administration in the rat. Synapse (New York, N.Y.). 44: 252-3. PMID 11984860 DOI: 10.1002/syn.10073 |
0.327 |
|
| 2002 |
Harrison AA, Gasparini F, Markou A. Nicotine potentiation of brain stimulation reward reversed by DH beta E and SCH 23390, but not by eticlopride, LY 314582 or MPEP in rats. Psychopharmacology. 160: 56-66. PMID 11862374 DOI: 10.1007/s00213-001-0953-6 |
0.468 |
|
| 2002 |
Chevrette J, Stellar JR, Hesse GW, Markou A. Both the shell of the nucleus accumbens and the central nucleus of the amygdala support amphetamine self-administration in rats. Pharmacology, Biochemistry, and Behavior. 71: 501-7. PMID 11830184 DOI: 10.1016/S0091-3057(01)00686-4 |
0.402 |
|
| 2002 |
Markou A, Kenny P. Nicotine withdrawal and antidepressants: Monoaminergic and glutamatergic modulation of reward European Neuropsychopharmacology. 12: 88-89. DOI: 10.1016/S0924-977X(02)80014-1 |
0.575 |
|
| 2001 |
Kenny PJ, Markou A. Neurobiology of the nicotine withdrawal syndrome. Pharmacology, Biochemistry, and Behavior. 70: 531-49. PMID 11796152 DOI: 10.1016/S0091-3057(01)00651-7 |
0.625 |
|
| 2001 |
Markou A, Paterson NE. The nicotinic antagonist methyllycaconitine has differential effects on nicotine self-administration and nicotine withdrawal in the rat. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 3: 361-73. PMID 11694204 DOI: 10.1080/14622200110073380 |
0.45 |
|
| 2001 |
Harrison AA, Liem YT, Markou A. Fluoxetine combined with a serotonin-1A receptor antagonist reversed reward deficits observed during nicotine and amphetamine withdrawal in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: 55-71. PMID 11377919 DOI: 10.1016/S0893-133X(00)00237-2 |
0.486 |
|
| 2001 |
Macey DJ, Froestl W, Koob GF, Markou A. Both GABA(B) receptor agonist and antagonists decreased brain stimulation reward in the rat. Neuropharmacology. 40: 676-85. PMID 11311895 DOI: 10.1016/S0028-3908(00)00204-5 |
0.576 |
|
| 2001 |
Markou A. Nicotine withdrawal and antidepressants: Serotonergic modulation of reward European Neuropsychopharmacology. 11: S140-S141. DOI: 10.1016/S0924-977X(01)80067-5 |
0.42 |
|
| 2000 |
Paterson NE, Myers C, Markou A. Effects of repeated withdrawal from continuous amphetamine administration on brain reward function in rats. Psychopharmacology. 152: 440-6. PMID 11140337 DOI: 10.1007/s002130000559 |
0.477 |
|
| 2000 |
Watkins SS, Koob GF, Markou A. Neural mechanisms underlying nicotine addiction: acute positive reinforcement and withdrawal. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 2: 19-37. PMID 11072438 DOI: 10.1080/14622200050011277 |
0.653 |
|
| 2000 |
Macey DJ, Koob GF, Markou A. CRF and urocortin decreased brain stimulation reward in the rat: reversal by a CRF receptor antagonist. Brain Research. 866: 82-91. PMID 10825483 DOI: 10.1016/S0006-8993(00)02229-0 |
0.603 |
|
| 2000 |
Watkins SS, Stinus L, Koob GF, Markou A. Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects. The Journal of Pharmacology and Experimental Therapeutics. 292: 1053-64. PMID 10688623 |
0.328 |
|
| 2000 |
Lin D, Koob GF, Markou A. Time-dependent alterations in ICSS thresholds associated with repeated amphetamine administrations. Pharmacology, Biochemistry, and Behavior. 65: 407-17. PMID 10683480 DOI: 10.1016/S0091-3057(99)00213-0 |
0.652 |
|
| 1999 |
Baldo BA, Koob GF, Markou A. Role of adenosine A2 receptors in brain stimulation reward under baseline conditions and during cocaine withdrawal in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 11017-26. PMID 10594082 |
0.573 |
|
| 1999 |
Lin D, Koob GF, Markou A. Differential effects of withdrawal from chronic amphetamine or fluoxetine administration on brain stimulation reward in the rat--interactions between the two drugs. Psychopharmacology. 145: 283-94. PMID 10494577 DOI: 10.1007/S002130051060 |
0.654 |
|
| 1999 |
Markou A, Arroyo M, Everitt BJ. Effects of contingent and non-contingent cocaine on drug-seeking behavior measured using a second-order schedule of cocaine reinforcement in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 20: 542-55. PMID 10327424 DOI: 10.1016/S0893-133X(98)00080-3 |
0.425 |
|
| 1999 |
Watkins SS, Epping-Jordan MP, Koob GF, Markou A. Blockade of nicotine self-administration with nicotinic antagonists in rats. Pharmacology, Biochemistry, and Behavior. 62: 743-51. PMID 10208381 DOI: 10.1016/S0091-3057(98)00226-3 |
0.642 |
|
| 1999 |
Baldo BA, Jain K, Veraldi L, Koob GF, Markou A. A dopamine D1 agonist elevates self-stimulation thresholds: comparison to other dopamine-selective drugs. Pharmacology, Biochemistry, and Behavior. 62: 659-72. PMID 10208371 DOI: 10.1016/S0091-3057(98)00206-8 |
0.69 |
|
| 1999 |
Harrison AA, Parsons LH, Koob GF, Markou A. RU 24969, a 5-HT1A/1B agonist, elevates brain stimulation reward thresholds: an effect reversed by GR 127935, a 5-HT1B/1D antagonist. Psychopharmacology. 141: 242-50. PMID 10027505 DOI: 10.1007/S002130050831 |
0.736 |
|
| 1999 |
Baldo BA, Markou A, Koob GF. Increased sensitivity to the locomotor depressant effect of a dopamine receptor antagonist during cocaine withdrawal in the rat. Psychopharmacology. 141: 135-44. PMID 9952037 DOI: 10.1007/s002130050817 |
0.718 |
|
| 1999 |
Baldo BA, Koob GF, Markou A. Role of Adenosine A2 Receptors in Brain Stimulation Reward under Baseline Conditions and during Cocaine Withdrawal in Rats The Journal of Neuroscience. 19: 11017-11026. DOI: 10.1523/JNEUROSCI.19-24-11017.1999 |
0.733 |
|
| 1998 |
Arroyo M, Markou A, Robbins TW, Everitt BJ. Acquisition, maintenance and reinstatement of intravenous cocaine self-administration under a second-order schedule of reinforcement in rats: effects of conditioned cues and continuous access to cocaine. Psychopharmacology. 140: 331-44. PMID 9877013 DOI: 10.1007/s002130050774 |
0.449 |
|
| 1998 |
Kosten TR, Markou A, Koob GF. Depression and stimulant dependence: neurobiology and pharmacotherapy. The Journal of Nervous and Mental Disease. 186: 737-45. PMID 9865811 DOI: 10.1097/00005053-199812000-00001 |
0.55 |
|
| 1998 |
Epping-Jordan MP, Watkins SS, Koob GF, Markou A. Dramatic decreases in brain reward function during nicotine withdrawal. Nature. 393: 76-9. PMID 9590692 DOI: 10.1038/30001 |
0.661 |
|
| 1998 |
Koob GF, Rocio M, Carrera A, Gold LH, Heyser CJ, Maldonado-Irizarry C, Markou A, Parsons LH, Roberts AJ, Schulteis G, Stinus L, Walker JR, Weissenborn R, Weiss F. Substance dependence as a compulsive behavior. Journal of Psychopharmacology (Oxford, England). 12: 39-48. PMID 9584967 DOI: 10.1177/026988119801200106 |
0.791 |
|
| 1998 |
Epping-Jordan MP, Markou A, Koob GF. The dopamine D-1 receptor antagonist SCH 23390 injected into the dorsolateral bed nucleus of the stria terminalis decreased cocaine reinforcement in the rat. Brain Research. 784: 105-15. PMID 9518570 DOI: 10.1016/S0006-8993(97)01190-6 |
0.644 |
|
| 1998 |
Markou A, Kosten TR, Koob GF. Neurobiological similarities in depression and drug dependence: a self-medication hypothesis. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 18: 135-74. PMID 9471114 DOI: 10.1016/S0893-133X(97)00113-9 |
0.604 |
|
| 1998 |
Stinus L, Belahsen O, Markou A, Koobb GF, Cadora M. IN NICOTINE DEPENDENT RATS, A PLACE AVERSION CONDITIONING IS INDUCED BYTHE ADMINISTRATION OF BOTH NICOTINE AND OPIATE RECEPTOR ANTAGONISTS Behavioural Pharmacology. 9: S83. DOI: 10.1097/00008877-199808000-00195 |
0.319 |
|
| 1997 |
Koob GF, Caine SB, Parsons L, Markou A, Weiss F. Opponent process model and psychostimulant addiction. Pharmacology, Biochemistry, and Behavior. 57: 513-21. PMID 9218276 DOI: 10.1016/S0091-3057(96)00438-8 |
0.803 |
|
| 1996 |
Whitelaw RB, Markou A, Robbins TW, Everitt BJ. Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement. Psychopharmacology. 127: 213-24. PMID 8912399 DOI: 10.1007/s002130050079 |
0.335 |
|
| 1996 |
Matthews K, Baldo BA, Markou A, Lown O, Overstreet DH, Koob GF. Rewarding electrical brain stimulation: similar thresholds for Flinders Sensitive Line Hypercholinergic and Flinders Resistant Line Hypocholinergic rats. Physiology & Behavior. 59: 1155-62. PMID 8737906 DOI: 10.1016/0031-9384(95)02212-0 |
0.712 |
|
| 1996 |
Whitelaw RB, Robbins TW, Everitt BJ, Markou A. Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement Psychopharmacology. 127: 213-224. DOI: 10.1007/BF02246129 |
0.444 |
|
| 1995 |
Schulteis G, Markou A, Cole M, Koob GF. Decreased brain reward produced by ethanol withdrawal. Proceedings of the National Academy of Sciences of the United States of America. 92: 5880-4. PMID 7597046 DOI: 10.1073/Pnas.92.13.5880 |
0.608 |
|
| 1994 |
Koob GF, Caine B, Markou A, Pulvirenti L, Weiss F. Role for the mesocortical dopamine system in the motivating effects of cocaine. Nida Research Monograph. 145: 1-18. PMID 8742805 |
0.808 |
|
| 1994 |
Mansbach RS, Markou A, Patrick GA. Lack of altered startle responding in rats following termination of self-administered or noncontingently infused cocaine Pharmacology, Biochemistry and Behavior. 48: 453-458. PMID 8090814 DOI: 10.1016/0091-3057(94)90552-5 |
0.463 |
|
| 1994 |
Markou A, Matthews K, Overstreet DH, Koob GF, Geyer MA. Flinders resistant hypocholinergic rats exhibit startle sensitization and reduced startle thresholds. Biological Psychiatry. 36: 680-8. PMID 7880937 DOI: 10.1016/0006-3223(94)91177-0 |
0.568 |
|
| 1993 |
Hammer RP, Pires WS, Markou A, Koob GF. Withdrawal following cocaine self-administration decreases regional cerebral metabolic rate in critical brain reward regions. Synapse (New York, N.Y.). 14: 73-80. PMID 8511720 DOI: 10.1002/syn.890140110 |
0.633 |
|
| 1993 |
Markou A, Weiss F, Gold LH, Caine SB, Schulteis G, Koob GF. Animal models of drug craving. Psychopharmacology. 112: 163-82. PMID 7871016 DOI: 10.1007/Bf02244907 |
0.761 |
|
| 1993 |
Koob GF, Markou A, Weiss F, Schulteis G. Opponent process and drug dependence: Neurobiological mechanisms Seminars in Neuroscience. 5: 351-358. DOI: 10.1016/S1044-5765(05)80043-0 |
0.713 |
|
| 1992 |
Markou A, Koob GF. Construct validity of a self-stimulation threshold paradigm: effects of reward and performance manipulations. Physiology & Behavior. 51: 111-9. PMID 1741436 DOI: 10.1016/0031-9384(92)90211-J |
0.602 |
|
| 1992 |
Weiss F, Hurd YL, Ungerstedt U, Markou A, Plotsky PM, Koob GF. Neurochemical correlates of cocaine and ethanol self-administration. Annals of the New York Academy of Sciences. 654: 220-41. PMID 1632585 DOI: 10.1111/J.1749-6632.1992.Tb25970.X |
0.712 |
|
| 1992 |
Weiss F, Markou A, Lorang MT, Koob GF. Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration. Brain Research. 593: 314-8. PMID 1450939 DOI: 10.1016/0006-8993(92)91327-B |
0.734 |
|
| 1992 |
Markou A, Koob GF. Bromocriptine reverses the elevation in intracranial self-stimulation thresholds observed in a rat model of cocaine withdrawal. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 7: 213-24. PMID 1388645 |
0.35 |
|
| 1992 |
Markou A, Hauger RL, Koob GF. Desmethylimipramine attenuates cocaine withdrawal in rats. Psychopharmacology. 109: 305-14. PMID 1365631 DOI: 10.1007/BF02245878 |
0.637 |
|
| 1991 |
Markou A, Koob GF. Postcocaine anhedonia. An animal model of cocaine withdrawal. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 4: 17-26. PMID 2003866 |
0.329 |
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