Emanuel Mignot - Publications

Stanford University, Palo Alto, CA 
Hypocretin, Narcolepsy, Zebrafish

293 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hanif U, Schneider LD, Trap L, Leary EB, Moore Iv H, Guilleminault C, Jennum PJ, Bjarup Dissing Sørensen H, Mignot EJM. Non-invasive machine learning estimation of effort differentiates sleep-disordered breathing pathology. Physiological Measurement. PMID 30736016 DOI: 10.1088/1361-6579/ab0559  0.52
2018 Plazzi G, Ruoff C, Lecendreux M, Dauvilliers Y, Rosen CL, Black J, Parvataneni R, Guinta D, Wang YG, Mignot E. Treatment of paediatric narcolepsy with sodium oxybate: a double-blind, placebo-controlled, randomised-withdrawal multicentre study and open-label investigation. The Lancet. Child & Adolescent Health. 2: 483-494. PMID 30169321 DOI: 10.1016/S2352-4642(18)30133-0  0.36
2016 Polomé P, Mignot E, Nasri A, Lipeme Kouyi G, Campan L, Hooge C, Rivière N. Urban domestic wastewater: how to reduce individual injection? Water Science and Technology : a Journal of the International Association On Water Pollution Research. 73: 144-152. PMID 26744945 DOI: 10.2166/wst.2015.473  1
2016 Plante DT, Finn LA, Hagen EW, Mignot E, Peppard PE. Subjective and objective measures of hypersomnolence demonstrate divergent associations with depression among participants in the Wisconsin sleep cohort study Journal of Clinical Sleep Medicine. 12: 571-578. DOI: 10.5664/jcsm.5694  1
2016 Mignot E, Cai W, Launay G, Riviere N, Escauriaza C. Coherent turbulent structures at the mixing-interface of a square open-channel lateral cavity Physics of Fluids. 28. DOI: 10.1063/1.4945264  1
2015 Christensen JA, Munk EG, Peppard PE, Young T, Mignot E, Sorensen HB, Jennum P. The diagnostic value of power spectra analysis of the sleep electroencephalography in narcoleptic patients. Sleep Medicine. 16: 1516-27. PMID 26611950 DOI: 10.1016/j.sleep.2015.09.005  1
2015 Li J, Moore H, Lin L, Young T, Finn L, Peppard PE, Mignot E. Association of low ferritin with PLM in the Wisconsin Sleep Cohort. Sleep Medicine. 16: 1413-8. PMID 26498245 DOI: 10.1016/j.sleep.2015.05.015  1
2015 Kawai M, O'Hara R, Einen M, Lin L, Mignot E. Narcolepsy in African Americans. Sleep. PMID 26158891 DOI: 10.5665/Sleep.5140  1
2015 Pizza F, Vandi S, Iloti M, Franceschini C, Liguori R, Mignot E, Plazzi G. Nocturnal Sleep Dynamics Identify Narcolepsy Type 1. Sleep. PMID 25845690 DOI: 10.5665/Sleep.4908  1
2015 Holm A, Lin L, Faraco J, Mostafavi S, Battle A, Zhu X, Levinson DF, Han F, Gammeltoft S, Jennum P, Mignot E, Kornum BR. EIF3G is associated with narcolepsy across ethnicities. European Journal of Human Genetics : Ejhg. PMID 25669430 DOI: 10.1038/Ejhg.2015.4  1
2015 Ollila HM, Ravel JM, Han F, Faraco J, Lin L, Zheng X, Plazzi G, Dauvilliers Y, Pizza F, Hong SC, Jennum P, Knudsen S, Kornum BR, Dong XS, Yan H, ... ... Mignot E, et al. HLA-DPB1 and HLA class I confer risk of and protection from narcolepsy. American Journal of Human Genetics. 96: 136-46. PMID 25574827 DOI: 10.1016/J.Ajhg.2014.12.010  1
2015 Jacob L, Leib R, Ollila HM, Bonvalet M, Adams CM, Mignot E. Comparison of Pandemrix and Arepanrix, two pH1N1 AS03-adjuvanted vaccines differentially associated with narcolepsy development. Brain, Behavior, and Immunity. 47: 44-57. PMID 25452148 DOI: 10.1016/j.bbi.2014.11.004  1
2015 Ollila HM, Fernandez-Vina M, Mignot E. HLA-DQ allele competition in narcolepsy: a comment on Tafti et al. DQB1 locus alone explains most of the risk and protection in narcolepsy with cataplexy in Europe. Sleep. 38: 147-51. PMID 25325462 DOI: 10.5665/sleep.4342  1
2015 Christensen JAE, Carrillo O, Leary EB, Peppard PE, Young T, Sorensen HBD, Jennum P, Mignot E. Sleep-stage transitions during polysomnographic recordings as diagnostic features of type 1 narcolepsy Sleep Medicine. DOI: 10.1016/j.sleep.2015.06.007  1
2015 Paquier A, Mignot E, Bazin PH. From hydraulic modelling to urban flood risk Procedia Engineering. 115: 37-44. DOI: 10.1016/j.proeng.2015.07.352  1
2014 Moore H, Leary E, Lee SY, Carrillo O, Stubbs R, Peppard P, Young T, Widrow B, Mignot E. Design and validation of a periodic leg movement detector. Plos One. 9: e114565. PMID 25489744 DOI: 10.1371/Journal.Pone.0114565  1
2014 Han F, Lin L, Schormair B, Pizza F, Plazzi G, Ollila HM, Nevsimalova S, Jennum P, Knudsen S, Winkelmann J, Coquillard C, Babrzadeh F, Strom TM, Wang C, Mindrinos M, ... ... Mignot E, et al. HLA DQB1*06:02 negative narcolepsy with hypocretin/orexin deficiency. Sleep. 37: 1601-8. PMID 25197808 DOI: 10.5665/Sleep.4066  1
2014 Canellas F, Lin L, Julià MR, Clemente A, Vives-Bauza C, Ollila HM, Hong SC, Arboleya SM, Einen MA, Faraco J, Fernandez-Vina M, Mignot E. Dual cases of type 1 narcolepsy with schizophrenia and other psychotic disorders. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 10: 1011-8. PMID 25142772 DOI: 10.5664/jcsm.4040  1
2014 Black J, Reaven NL, Funk SE, McGaughey K, Ohayon M, Guilleminault C, Ruoff C, Mignot E. The Burden of Narcolepsy Disease (BOND) study: health-care utilization and cost findings. Sleep Medicine. 15: 522-9. PMID 24768358 DOI: 10.1016/j.sleep.2014.02.001  0.52
2014 Zhou X, Wang J, Zou H, Ward MM, Weisman MH, Espitia MG, Xiao X, Petersdorf E, Mignot E, Martin J, Gensler LS, Scheet P, Reveille JD. MICA, a gene contributing strong susceptibility to ankylosing spondylitis. Annals of the Rheumatic Diseases. 73: 1552-7. PMID 23727634 DOI: 10.1136/Annrheumdis-2013-203352  1
2014 Bazin PH, Nakagawa H, Kawaike K, Paquier A, Mignot E. Modeling flow exchanges between a street and an underground drainage pipe during urban floods Journal of Hydraulic Engineering. 140. DOI: 10.1061/(ASCE)HY.1943-7900.0000917  1
2013 Valko PO, Gavrilov YV, Yamamoto M, Reddy H, Haybaeck J, Mignot E, Baumann CR, Scammell TE. Increase of histaminergic tuberomammillary neurons in narcolepsy. Annals of Neurology. 74: 794-804. PMID 24006291 DOI: 10.1002/ana.24019  1
2013 Roth T, Dauvilliers Y, Mignot E, Montplaisir J, Paul J, Swick T, Zee P. Disrupted nighttime sleep in narcolepsy. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 9: 955-65. PMID 23997709 DOI: 10.5664/Jcsm.3004  1
2013 Pedroso JL, Povoas Barsottini OG, Lin L, Melberg A, Oliveira AS, Mignot E. A novel de novo exon 21 DNMT1 mutation causes cerebellar ataxia, deafness, and narcolepsy in a Brazilian patient. Sleep. 36: 1257-9, 1259A. PMID 23904686 DOI: 10.5665/sleep.2898  1
2013 Pizza F, Vandi S, Poli F, Moghadam KK, Franceschini C, Bellucci C, Cipolli C, Ingravallo F, Natalini G, Mignot E, Plazzi G. Narcolepsy with cataplexy mimicry: the strange case of two sisters. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 9: 611-2. PMID 23772196 DOI: 10.5664/Jcsm.2764  1
2013 Nikodemova M, Finn L, Mignot E, Salzieder N, Peppard PE. Association of sleep disordered breathing and cognitive deficit in APOE ε4 carriers. Sleep. 36: 873-80. PMID 23729930 DOI: 10.5665/sleep.2714  1
2013 Mahlios J, De la Herrán-Arita AK, Mignot E. The autoimmune basis of narcolepsy. Current Opinion in Neurobiology. 23: 767-73. PMID 23725858 DOI: 10.1016/j.conb.2013.04.013  1
2013 Andlauer O, Moore H, Jouhier L, Drake C, Peppard PE, Han F, Hong SC, Poli F, Plazzi G, O'Hara R, Haffen E, Roth T, Young T, Mignot E. Nocturnal rapid eye movement sleep latency for identifying patients with narcolepsy/hypocretin deficiency. Jama Neurology. 70: 891-902. PMID 23649748 DOI: 10.1001/Jamaneurol.2013.1589  1
2013 Mignot E. Physiology. The perfect hypnotic? Science (New York, N.Y.). 340: 36-8. PMID 23559238 DOI: 10.1126/science.1237998  1
2013 Singh AK, Mahlios J, Mignot E. Genetic association, seasonal infections and autoimmune basis of narcolepsy. Journal of Autoimmunity. 43: 26-31. PMID 23497937 DOI: 10.1016/j.jaut.2013.02.003  1
2013 Poli F, Pizza F, Mignot E, Ferri R, Pagotto U, Taheri S, Finotti E, Bernardi F, Pirazzoli P, Cicognani A, Balsamo A, Nobili L, Bruni O, Plazzi G. High prevalence of precocious puberty and obesity in childhood narcolepsy with cataplexy. Sleep. 36: 175-81. PMID 23372264 DOI: 10.5665/Sleep.2366  1
2013 Mignot E, Zeng C, Dominguez G, Li CW, Rivière N, Bazin PH. Impact of topographic obstacles on the discharge distribution in open-channel bifurcations Journal of Hydrology. 494: 10-19. DOI: 10.1016/j.jhydrol.2013.04.023  1
2012 Andlauer O, Moore H, Hong SC, Dauvilliers Y, Kanbayashi T, Nishino S, Han F, Silber MH, Rico T, Einen M, Kornum BR, Jennum P, Knudsen S, Nevsimalova S, Poli F, ... ... Mignot E, et al. Predictors of hypocretin (orexin) deficiency in narcolepsy without cataplexy. Sleep. 35: 1247-55F. PMID 22942503 DOI: 10.5665/Sleep.2080  0.64
2012 Han F, Lin L, Li J, Dong SX, An P, Zhao L, Liu NY, Li QY, Yan H, Gao ZC, Faraco J, Strohl KP, Liu X, Miyadera H, Mignot E. HLA-DQ association and allele competition in Chinese narcolepsy. Tissue Antigens. 80: 328-35. PMID 22862152 DOI: 10.1111/j.1399-0039.2012.01948.x  1
2012 Zeitzer JM, Kodama T, Buckmaster CL, Honda Y, Lyons DM, Nishino S, Mignot E. Time-course of cerebrospinal fluid histamine in the wake-consolidated squirrel monkey. Journal of Sleep Research. 21: 189-94. PMID 21910776 DOI: 10.1111/j.1365-2869.2011.00957.x  0.64
2011 Palaia V, Poli F, Pizza F, Antelmi E, Franceschini C, Moghadam KK, Provini F, Pagotto U, Montagna P, Schenck CH, Mignot E, Plazzi G. Narcolepsy with cataplexy associated with nocturnal compulsive behaviors: a case-control study. Sleep. 34: 1365-71. PMID 21966068 DOI: 10.5665/Sleep.1280  1
2011 Aran A, Lin L, Finn LA, Weiner K, Peppard P, Young T, Mignot E. Post-streptococcal antibodies are associated with metabolic syndrome in a population-based cohort. Plos One. 6: e25017. PMID 21949836 DOI: 10.1371/journal.pone.0025017  1
2011 Sehgal A, Mignot E. Genetics of sleep and sleep disorders. Cell. 146: 194-207. PMID 21784243 DOI: 10.1016/j.cell.2011.07.004  1
2011 Winkelmann J, Czamara D, Schormair B, Knauf F, Schulte EC, Trenkwalder C, Dauvilliers Y, Polo O, Högl B, Berger K, Fuhs A, Gross N, Stiasny-Kolster K, Oertel W, Bachmann CG, ... ... Mignot E, et al. Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1. Plos Genetics. 7: e1002171. PMID 21779176 DOI: 10.1371/Journal.Pgen.1002171  1
2011 Han F, Lin L, Li J, Aran A, Dong SX, An P, Zhao L, Li M, Li QY, Yan H, Wang JS, Gao HY, Li M, Gao ZC, Strohl KP, ... Mignot E, et al. Presentations of primary hypersomnia in Chinese children. Sleep. 34: 627-32. PMID 21532956 DOI: 10.1093/sleep/34.5.627  1
2011 Vardeny O, Peppard PE, Finn LA, Faraco JH, Mignot E, Hla KM. β2 adrenergic receptor polymorphisms and nocturnal blood pressure dipping status in the Wisconsin Sleep Cohort Study. Journal of the American Society of Hypertension : Jash. 5: 114-22. PMID 21414566 DOI: 10.1016/j.jash.2011.01.005  1
2011 Zeitzer JM, Fisicaro RA, Grove ME, Mignot E, Yesavage JA, Friedman L. Faster REM sleep EEG and worse restedness in older insomniacs with HLA DQB1*0602. Psychiatry Research. 187: 397-400. PMID 21292329 DOI: 10.1016/j.psychres.2011.01.007  1
2011 Kornum BR, Kawashima M, Faraco J, Lin L, Rico TJ, Hesselson S, Axtell RC, Kuipers H, Weiner K, Hamacher A, Kassack MU, Han F, Knudsen S, Li J, Dong X, ... ... Mignot E, et al. Common variants in P2RY11 are associated with narcolepsy. Nature Genetics. 43: 66-71. PMID 21170044 DOI: 10.1038/Ng.734  1
2011 Nishino S, Mignot E. Narcolepsy and cataplexy. Handbook of Clinical Neurology. 99: 783-814. PMID 21056228 DOI: 10.1016/B978-0-444-52007-4.00007-2  1
2011 Mignot E, Dauvilliers Y, Montplaisir J. Comment on the letter to the editor by Dr. Marcus on the association between narcolepsy and H1N1 exposure Sleep. 34: 689-690. DOI: 10.5665/Sleep.1024  1
2010 Aran A, Einen M, Lin L, Plazzi G, Nishino S, Mignot E. Clinical and therapeutic aspects of childhood narcolepsy-cataplexy: a retrospective study of 51 children. Sleep. 33: 1457-64. PMID 21102987  1
2010 Dauvilliers Y, Montplaisir J, Cochen V, Desautels A, Einen M, Lin L, Kawashima M, Bayard S, Monaca C, Tiberge M, Filipini D, Tripathy A, Nguyen BH, Kotagal S, Mignot E. Post-H1N1 narcolepsy-cataplexy. Sleep. 33: 1428-30. PMID 21102981 DOI: 10.1093/Sleep/33.11.1428  1
2010 Tanaka S, Kodama T, Nonaka T, Toyoda H, Arai M, Fukazawa M, Honda Y, Honda M, Mignot E. Transcriptional regulation of the hypocretin/orexin gene by NR6A1. Biochemical and Biophysical Research Communications. 403: 178-83. PMID 21056546 DOI: 10.1016/j.bbrc.2010.11.001  1
2010 Goel N, Banks S, Mignot E, Dinges DF. DQB1*0602 predicts interindividual differences in physiologic sleep, sleepiness, and fatigue. Neurology. 75: 1509-19. PMID 20975052 DOI: 10.1212/Wnl.0B013E3181F9615D  1
2010 Taheri S, Mignot E. Sleep well and stay slim: dream or reality? Annals of Internal Medicine. 153: 475-6. PMID 20921547 DOI: 10.7326/0003-4819-153-7-201010050-00012  1
2010 Appelbaum L, Wang G, Yokogawa T, Skariah GM, Smith SJ, Mourrain P, Mignot E. Circadian and homeostatic regulation of structural synaptic plasticity in hypocretin neurons. Neuron. 68: 87-98. PMID 20920793 DOI: 10.1016/J.Neuron.2010.09.006  1
2010 Aran A, Weiner K, Lin L, Finn LA, Greco MA, Peppard P, Young T, Ofran Y, Mignot E. Post-streptococcal auto-antibodies inhibit protein disulfide isomerase and are associated with insulin resistance. Plos One. 5: e12875. PMID 20886095 DOI: 10.1371/journal.pone.0012875  1
2010 Schwimmer H, Stauss HM, Abboud F, Nishino S, Mignot E, Zeitzer JM. Effects of sleep on the cardiovascular and thermoregulatory systems: a possible role for hypocretins. Journal of Applied Physiology (Bethesda, Md. : 1985). 109: 1053-63. PMID 20705949 DOI: 10.1152/japplphysiol.00516.2010  1
2010 Kawashima M, Lin L, Tanaka S, Jennum P, Knudsen S, Nevsimalova S, Plazzi G, Mignot E. Anti-Tribbles homolog 2 (TRIB2) autoantibodies in narcolepsy are associated with recent onset of cataplexy. Sleep. 33: 869-74. PMID 20614846 DOI: 10.1093/Sleep/33.7.869  1
2010 Hirst J, Mignot E, Stein MT. Episodic hypersomnia and unusual behaviors in a 14-year old adolescent. Journal of Developmental and Behavioral Pediatrics : Jdbp. 31: S18-20. PMID 20414066 DOI: 10.1097/DBP.0b013e3181d83050  1
2010 Plazzi G, Tonon C, Rubboli G, Poli F, Franceschini C, Pizza F, Bisulli A, Rizzo G, Mignot E, Montagna P, Lodi R. Narcolepsy with cataplexy associated with holoprosencephaly misdiagnosed as epileptic drop attacks. Movement Disorders : Official Journal of the Movement Disorder Society. 25: 788-90. PMID 20131387 DOI: 10.1002/Mds.23008  1
2010 Han F, Mignot E, Wei YC, Dong SX, Li J, Lin L, An P, Wang LH, Wang JS, He MZ, Gao HY, Li M, Gao ZC, Strohl KP. Ventilatory chemoresponsiveness, narcolepsy-cataplexy and human leukocyte antigen DQB1*0602 status. The European Respiratory Journal. 36: 577-83. PMID 20110394 DOI: 10.1183/09031936.00174609  1
2010 Vetrugno R, D'Angelo R, Moghadam KK, Vandi S, Franceschini C, Mignot E, Montagna P, Plazzi G. Behavioural and neurophysiological correlates of human cataplexy: a video-polygraphic study. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 121: 153-62. PMID 19955018 DOI: 10.1016/J.Clinph.2009.10.012  1
2010 Lammers GJ, Bassetti C, Billiard M, Black J, Broughton R, Dauvilliers Y, Ferini Strambi L, Garcia-Borreguero D, Goswami M, Högl B, Iranzo A, Jennum P, Khatami R, Lecendreux M, Mayer G, ... Mignot E, et al. Sodium oxybate is an effective and safe treatment for narcolepsy. Sleep Medicine. 11: 105-6; author reply . PMID 19846338 DOI: 10.1016/J.Sleep.2009.08.003  1
2010 Ghostine R, Mignot E, Abdallah M, Lawniczak F, Vazquez J, Mosé R, Grégoire C. Discontinuous Galerkin finite-element method for simulation of flood in crossroads Journal of Hydraulic Engineering. 136: 474-482. DOI: 10.1061/(ASCE)HY.1943-7900.0000209  1
2010 Mignot E, Cienfuegos R. Energy dissipation and turbulent production in weak hydraulic jumps Journal of Hydraulic Engineering. 136: 116-121. DOI: 10.1061/(ASCE)HY.1943-7900.0000124  1
2010 Nishino S, Mignot E. Wake-Promoting Medications: Basic Mechanisms and Pharmacology Principles and Practice of Sleep Medicine: Fifth Edition. 510-526. DOI: 10.1016/B978-1-4160-6645-3.00044-X  0.64
2010 Plazzi G, Tonon C, Rubboli G, Franceschini C, Pizza F, Bisulli A, Rizzo G, Mignot E, Montagna E, Lodi R. Narcolepsy with cataplexy associated with holoprosencephaly misdiagnosed as epileptic drop attacks (Movement Disorders (2010) 25, 6, (788-790)) Movement Disorders. 25: 1764. DOI: 10.1002/Mds.23398  1
2009 Appelbaum L, Wang GX, Maro GS, Mori R, Tovin A, Marin W, Yokogawa T, Kawakami K, Smith SJ, Gothilf Y, Mignot E, Mourrain P. Sleep-wake regulation and hypocretin-melatonin interaction in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 106: 21942-7. PMID 19966231 DOI: 10.1073/Pnas.906637106  1
2009 Poli F, Plazzi G, Di Dalmazi G, Ribichini D, Vicennati V, Pizza F, Mignot E, Montagna P, Pasquali R, Pagotto U. Body mass index-independent metabolic alterations in narcolepsy with cataplexy. Sleep. 32: 1491-7. PMID 19928388 DOI: 10.1093/Sleep/32.11.1491  1
2009 Berman JR, Skariah G, Maro GS, Mignot E, Mourrain P. Characterization of two melanin-concentrating hormone genes in zebrafish reveals evolutionary and physiological links with the mammalian MCH system. The Journal of Comparative Neurology. 517: 695-710. PMID 19827161 DOI: 10.1002/Cne.22171  1
2009 Mignot E, Huguenard JR. Resting our cortices by going DOWN to sleep. Neuron. 63: 719-21. PMID 19778500 DOI: 10.1016/j.neuron.2009.09.008  1
2009 Eriksson KS, Mignot E. T-box 3 is expressed in the adult mouse hypothalamus and medulla. Brain Research. 1302: 233-9. PMID 19765559 DOI: 10.1016/j.brainres.2009.08.101  1
2009 Zeitzer JM, Buckmaster CL, Landolt HP, Lyons DM, Mignot E. Modafinil and γ-hydroxybutyrate have sleep state-specific pharmacological actions on hypocretin-1 physiology in a primate model of human sleep. Behavioural Pharmacology. 20: 643-52. PMID 19752724 DOI: 10.1097/FBP.0b013e328331b9db  1
2009 Aran A, Lin L, Nevsimalova S, Plazzi G, Hong SC, Weiner K, Zeitzer J, Mignot E. Elevated anti-streptococcal antibodies in patients with recent narcolepsy onset. Sleep. 32: 979-83. PMID 19725248 DOI: 10.1093/Sleep/32.8.979  1
2009 Honda M, Arai T, Fukazawa M, Honda Y, Tsuchiya K, Salehi A, Akiyama H, Mignot E. Absence of ubiquitinated inclusions in hypocretin neurons of patients with narcolepsy. Neurology. 73: 511-7. PMID 19687452 DOI: 10.1212/Wnl.0B013E3181B2A6Af  1
2009 Goel N, Banks S, Mignot E, Dinges DF. PER3 polymorphism predicts cumulative sleep homeostatic but not neurobehavioral changes to chronic partial sleep deprivation. Plos One. 4: e5874. PMID 19516903 DOI: 10.1371/Journal.Pone.0005874  1
2009 Tonon C, Franceschini C, Testa C, Manners DN, Poli F, Mostacci B, Mignot E, Montagna P, Barbiroli B, Lodi R, Plazzi G. Distribution of neurochemical abnormalities in patients with narcolepsy with cataplexy: An in vivo brain proton MR spectroscopy study. Brain Research Bulletin. 80: 147-50. PMID 19463917 DOI: 10.1016/J.Brainresbull.2009.05.010  1
2009 Hallmayer J, Faraco J, Lin L, Hesselson S, Winkelmann J, Kawashima M, Mayer G, Plazzi G, Nevsimalova S, Bourgin P, Hong SC, Hong SS, Honda Y, Honda M, Högl B, ... ... Mignot E, et al. Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nature Genetics. 41: 708-11. PMID 19412176 DOI: 10.1038/Ng.372  1
2009 Nishino S, Sakurai E, Nevsimalova S, Yoshida Y, Watanabe T, Yanai K, Mignot E. Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to healthy controls. Sleep. 32: 175-80. PMID 19238804  1
2009 Honda M, Eriksson KS, Zhang S, Tanaka S, Lin L, Salehi A, Hesla PE, Maehlen J, Gaus SE, Yanagisawa M, Sakurai T, Taheri S, Tsuchiya K, Honda Y, Mignot E. IGFBP3 colocalizes with and regulates hypocretin (orexin). Plos One. 4: e4254. PMID 19158946 DOI: 10.1371/Journal.Pone.0004254  1
2009 Mignot E, Aran A. The immune system, the brain and narcolepsy Future Neurology. 4: 683-687. DOI: 10.2217/fnl.09.57  1
2009 Mignot E, Rivière N, Perkins RJ, Paquier A, Travin G. Closure to "Flow patterns in a four-branch junction with supercritical flow" by Emmanuel Mignot, Nicolas Rivière, Richard Perkins, and André Paquier Journal of Hydraulic Engineering. 135: 1023-1024. DOI: 10.1061/(ASCE)HY.1943-7900.0000119  1
2009 Mignot E, Hurther D, Barthelemy E. On the structure of shear stress and turbulent kinetic energy flux across the roughness layer of a gravel-bed channel flow Journal of Fluid Mechanics. 638: 423-452. DOI: 10.1017/S0022112009990772  1
2009 Mignot E, Barthelemy E, Hurther D. Double-averaging analysis and local flow characterization of near-bed turbulence in gravel-bed channel flows Journal of Fluid Mechanics. 618: 279-303. DOI: 10.1017/S0022112008004643  1
2009 Mignot E, Cienfuegos R. On the application of a Boussinesq model to river flows including shocks Coastal Engineering. 56: 23-31. DOI: 10.1016/j.coastaleng.2008.06.007  1
2009 El Kadi Abderrezzak K, Paquier A, Mignot E. Modelling flash flood propagation in urban areas using a two-dimensional numerical model Natural Hazards. 50: 433-460. DOI: 10.1007/s11069-008-9300-0  1
2008 Donadio V, Plazzi G, Vandi S, Franceschini C, Karlsson T, Montagna P, Vetrugno R, Bugiardini E, Mignot E, Liguori R. Sympathetic and cardiovascular activity during cataplexy in narcolepsy. Journal of Sleep Research. 17: 458-63. PMID 19021855 DOI: 10.1111/J.1365-2869.2008.00682.X  1
2008 Miyagawa T, Kawashima M, Nishida N, Ohashi J, Kimura R, Fujimoto A, Shimada M, Morishita S, Shigeta T, Lin L, Hong SC, Faraco J, Shin YK, Jeong JH, Okazaki Y, ... ... Mignot E, et al. Variant between CPT1B and CHKB associated with susceptibility to narcolepsy. Nature Genetics. 40: 1324-8. PMID 18820697 DOI: 10.1038/ng.231  1
2008 Plazzi G, Poli F, Franceschini C, Parmeggiani A, Pirazzoli P, Bernardi F, Mignot E, Cicognani A, Montagna P. Intravenous high-dose immunoglobulin treatment in recent onset childhood narcolepsy with cataplexy. Journal of Neurology. 255: 1549-54. PMID 18769859 DOI: 10.1007/S00415-008-0983-7  1
2008 Mishima K, Fujiki N, Yoshida Y, Sakurai T, Honda M, Mignot E, Nishino S. Hypocretin receptor expression in canine and murine narcolepsy models and in hypocretin-ligand deficient human narcolepsy. Sleep. 31: 1119-26. PMID 18714784  1
2008 Alaez C, Lin L, Flores-A H, Vazquez M, Munguia A, Mignot E, Haro R, Baker H, Gorodezky C. Association of narcolepsy-cataplexy with HLA-DRB1 and DQB1 in Mexican patients: a relationship between HLA and gender is suggested. Bmc Medical Genetics. 9: 79. PMID 18706091 DOI: 10.1186/1471-2350-9-79  1
2008 Bourgin P, Zeitzer JM, Mignot E. CSF hypocretin-1 assessment in sleep and neurological disorders. The Lancet. Neurology. 7: 649-62. PMID 18565458 DOI: 10.1016/S1474-4422(08)70140-6  1
2008 Reiss AL, Hoeft F, Tenforde AS, Chen W, Mobbs D, Mignot EJ. Anomalous hypothalamic responses to humor in cataplexy. Plos One. 3: e2225. PMID 18493621 DOI: 10.1371/journal.pone.0002225  1
2008 Mignot E. Why we sleep: the temporal organization of recovery. Plos Biology. 6: e106. PMID 18447584 DOI: 10.1371/journal.pbio.0060106  1
2008 Arnulf I, Lin L, Gadoth N, File J, Lecendreux M, Franco P, Zeitzer J, Lo B, Faraco JH, Mignot E. Kleine-Levin syndrome: a systematic study of 108 patients. Annals of Neurology. 63: 482-93. PMID 18438947 DOI: 10.1002/Ana.21333  1
2008 Mignot E. Excessive daytime sleepiness: population and etiology versus nosology. Sleep Medicine Reviews. 12: 87-94. PMID 18342260 DOI: 10.1016/j.smrv.2007.12.006  1
2008 Serra L, Montagna P, Mignot E, Lugaresi E, Plazzi G. Cataplexy features in childhood narcolepsy. Movement Disorders : Official Journal of the Movement Disorder Society. 23: 858-65. PMID 18307264 DOI: 10.1002/Mds.21965  1
2008 Eriksson KS, Zhang S, Lin L, Larivière RC, Julien JP, Mignot E. The type III neurofilament peripherin is expressed in the tuberomammillary neurons of the mouse. Bmc Neuroscience. 9: 26. PMID 18294400 DOI: 10.1186/1471-2202-9-26  1
2008 Colas D, Valletta JS, Takimoto-Kimura R, Nishino S, Fujiki N, Mobley WC, Mignot E. Sleep and EEG features in genetic models of Down syndrome. Neurobiology of Disease. 30: 1-7. PMID 18282758 DOI: 10.1016/J.Nbd.2007.07.014  1
2008 Ciafaloni E, Mignot E, Sansone V, Hilbert JE, Lin L, Lin X, Liu LC, Pigeon WR, Perlis ML, Thornton CA. The hypocretin neurotransmission system in myotonic dystrophy type 1. Neurology. 70: 226-30. PMID 18195268 DOI: 10.1212/01.wnl.0000296827.20167.98  1
2008 Mignot E, Paquier A, Rivière N. Experimental and numerical modeling of symmetrical four-branch supercritical cross junction flow Journal of Hydraulic Research. 46: 723-738. DOI: 10.3826/jhr.2008.2961  1
2007 Hirst J, Mignot E, Stein MT. Episodic hypersomnia and unusual behaviors in a 14-year old adolescent. Journal of Developmental and Behavioral Pediatrics : Jdbp. 28: 475-7. PMID 18091094 DOI: 10.1097/DBP.0b013e31815d4c60  1
2007 Yokogawa T, Marin W, Faraco J, Pézeron G, Appelbaum L, Zhang J, Rosa F, Mourrain P, Mignot E. Characterization of sleep in zebrafish and insomnia in hypocretin receptor mutants. Plos Biology. 5: e277. PMID 17941721 DOI: 10.1371/Journal.Pbio.0050277  1
2007 Appelbaum L, Skariah G, Mourrain P, Mignot E. Comparative expression of p2x receptors and ecto-nucleoside triphosphate diphosphohydrolase 3 in hypocretin and sensory neurons in zebrafish. Brain Research. 1174: 66-75. PMID 17868657 DOI: 10.1016/J.Brainres.2007.06.103  1
2007 Szklo-Coxe M, Young T, Finn L, Mignot E. Depression: relationships to sleep paralysis and other sleep disturbances in a community sample. Journal of Sleep Research. 16: 297-312. PMID 17716279 DOI: 10.1111/j.1365-2869.2007.00600.x  1
2007 Taheri S, Austin D, Lin L, Nieto FJ, Young T, Mignot E. Correlates of serum C-reactive protein (CRP)--no association with sleep duration or sleep disordered breathing. Sleep. 30: 991-6. PMID 17702268  1
2007 Zeitzer JM, Buckmaster CL, Lyons DM, Mignot E. Increasing length of wakefulness and modulation of hypocretin-1 in the wake-consolidated squirrel monkey. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R1736-42. PMID 17686881 DOI: 10.1152/ajpregu.00460.2007  1
2007 Mignot E. A step forward for restless legs syndrome. Nature Genetics. 39: 938-9. PMID 17660808 DOI: 10.1038/ng0807-938  1
2007 Zhang S, Lin L, Kaur S, Thankachan S, Blanco-Centurion C, Yanagisawa M, Mignot E, Shiromani PJ. The development of hypocretin (orexin) deficiency in hypocretin/ataxin-3 transgenic rats. Neuroscience. 148: 34-43. PMID 17618058 DOI: 10.1016/J.Neuroscience.2007.05.029  1
2007 Nevsimalova S, Prihodova I, Kemlink D, Lin L, Mignot E. REM behavior disorder (RBD) can be one of the first symptoms of childhood narcolepsy. Sleep Medicine. 8: 784-6. PMID 17569582 DOI: 10.1016/j.sleep.2006.11.018  1
2007 Schenck CH, Bassetti CL, Arnulf I, Mignot E. English translations of the first clinical reports on narcolepsy and cataplexy by Westphal and Gélineau in the late 19th century, with commentary. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 3: 301-11. PMID 17561602  1
2007 Lindberg J, Saetre P, Nishino S, Mignot E, Jazin E. Reduced expression of TAC1, PENK and SOCS2 in Hcrtr-2 mutated narcoleptic dog brain. Bmc Neuroscience. 8: 34. PMID 17521418 DOI: 10.1186/1471-2202-8-34  1
2007 Patel SR, Larkin EK, Mignot E, Lin L, Redline S. The association of angiotensin converting enzyme (ACE) polymorphisms with sleep apnea and hypertension. Sleep. 30: 531-3. PMID 17520798  1
2007 Renier C, Faraco JH, Bourgin P, Motley T, Bonaventure P, Rosa F, Mignot E. Genomic and functional conservation of sedative-hypnotic targets in the zebrafish. Pharmacogenetics and Genomics. 17: 237-53. PMID 17496723 DOI: 10.1097/FPC.0b013e3280119d62  1
2007 Zhang S, Zeitzer JM, Sakurai T, Nishino S, Mignot E. Sleep/wake fragmentation disrupts metabolism in a mouse model of narcolepsy. The Journal of Physiology. 581: 649-63. PMID 17379635 DOI: 10.1113/Jphysiol.2007.129510  1
2007 Taiwo OB, Russell IJ, Mignot E, Lin L, Michalek JE, Haynes W, Xiao Y, Zeitzer JM, Larson AA. Normal cerebrospinal fluid levels of hypocretin-1 (orexin A) in patients with fibromyalgia syndrome. Sleep Medicine. 8: 260-5. PMID 17369087 DOI: 10.1016/j.sleep.2006.08.015  1
2007 Friedman LF, Zeitzer JM, Lin L, Hoff D, Mignot E, Peskind ER, Yesavage JA. In Alzheimer disease, increased wake fragmentation found in those with lower hypocretin-1. Neurology. 68: 793-4. PMID 17339595 DOI: 10.1212/01.wnl.0000256731.57544.f9  1
2007 Dauvilliers Y, Arnulf I, Mignot E. Narcolepsy with cataplexy. Lancet. 369: 499-511. PMID 17292770 DOI: 10.1016/S0140-6736(07)60237-2  1
2007 Rubio JP, Bahlo M, Stankovich J, Burfoot RK, Johnson LJ, Huxtable S, Butzkueven H, Lin L, Taylor BV, Speed TP, Kilpatrick TJ, Mignot E, Foote SJ. Analysis of extended HLA haplotypes in multiple sclerosis and narcolepsy families confirms a predisposing effect for the class I region in Tasmanian MS patients. Immunogenetics. 59: 177-86. PMID 17256150 DOI: 10.1007/S00251-006-0183-5  1
2007 Mignot E, Takahashi JS. A circadian sleep disorder reveals a complex clock. Cell. 128: 22-3. PMID 17218251 DOI: 10.1016/j.cell.2006.12.024  1
2007 Hong SC, Lin L, Lo B, Jeong JH, Shin YK, Kim SY, Kweon Y, Zhang J, Einen M, Smith A, Hansen J, Grumet FC, Mignot E. DQB1*0301 and DQB1*0601 modulate narcolepsy susceptibility in Koreans. Human Immunology. 68: 59-68. PMID 17207713 DOI: 10.1016/j.humimm.2006.10.006  1
2006 Ferri R, Zucconi M, Manconi M, Bruni O, Ferini-Strambi L, Vandi S, Montagna P, Mignot E, Plazzi G. Different periodicity and time structure of leg movements during sleep in narcolepsy/cataplexy and restless legs syndrome. Sleep. 29: 1587-94. PMID 17252889 DOI: 10.1093/Sleep/29.12.1587  1
2006 Hong SC, Lin L, Jeong JH, Shin YK, Han JH, Lee JH, Lee SP, Zhang J, Einen M, Mignot E. A study of the diagnostic utility of HLA typing, CSF hypocretin-1 measurements, and MSLT testing for the diagnosis of narcolepsy in 163 Korean patients with unexplained excessive daytime sleepiness. Sleep. 29: 1429-38. PMID 17162989  1
2006 Arnulf I, Lin L, Zhang J, Russell IJ, Ripley B, Einen M, Nevsimalova S, Bassetti C, Bourgin P, Nishino S, Mignot E. CSF versus serum leptin in narcolepsy: is there an effect of hypocretin deficiency? Sleep. 29: 1017-24. PMID 16944669 DOI: 10.1093/Sleep/29.8.1017  1
2006 Faraco JH, Appelbaum L, Marin W, Gaus SE, Mourrain P, Mignot E. Regulation of hypocretin (orexin) expression in embryonic zebrafish. The Journal of Biological Chemistry. 281: 29753-61. PMID 16867991 DOI: 10.1074/Jbc.M605811200  1
2006 Zeitzer JM, Nishino S, Mignot E. The neurobiology of hypocretins (orexins), narcolepsy and related therapeutic interventions. Trends in Pharmacological Sciences. 27: 368-74. PMID 16766052 DOI: 10.1016/j.tips.2006.05.006  1
2006 Plazzi G, Parmeggiani A, Mignot E, Lin L, Scano MC, Posar A, Bernardi F, Lodi R, Tonon C, Barbiroli B, Montagna P, Cicognani A. Narcolepsy-cataplexy associated with precocious puberty. Neurology. 66: 1577-9. PMID 16717224 DOI: 10.1212/01.Wnl.0000216142.21375.71  1
2005 Shepard JW, Buysse DJ, Chesson AL, Dement WC, Goldberg R, Guilleminault C, Harris CD, Iber C, Mignot E, Mitler MM, Moore KE, Phillips BA, Quan SF, Rosenberg RS, Roth T, et al. History of the development of sleep medicine in the United States. Journal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine. 1: 61-82. PMID 17561617  1
2005 Mignot E, Nishino S. Emerging therapies in narcolepsy-cataplexy. Sleep. 28: 754-63. PMID 16477963  1
2005 Gaus SE, Lin L, Mignot E. CSF hypocretin levels are normal in Huntington's disease patients. Sleep. 28: 1607-8. PMID 16408421 DOI: 10.1093/Sleep/28.12.1607  1
2005 Cizza G, Skarulis M, Mignot E. A link between short sleep and obesity: building the evidence for causation. Sleep. 28: 1217-20. PMID 16295203  1
2005 Crocker A, España RA, Papadopoulou M, Saper CB, Faraco J, Sakurai T, Honda M, Mignot E, Scammell TE. Concomitant loss of dynorphin, NARP, and orexin in narcolepsy. Neurology. 65: 1184-8. PMID 16247044 DOI: 10.1212/01.Wnl.0000168173.71940.Ab  1
2005 Arnulf I, Zeitzer JM, File J, Farber N, Mignot E. Kleine-Levin syndrome: a systematic review of 186 cases in the literature. Brain : a Journal of Neurology. 128: 2763-76. PMID 16230322 DOI: 10.1093/brain/awh620  1
2005 Chen W, Black J, Call P, Mignot E. Late-onset narcolepsy presenting as rapidly progressing muscle weakness: response to plasmapheresis. Annals of Neurology. 58: 489-90. PMID 16130098 DOI: 10.1002/ana.20603  1
2005 Tachibana N, Taniike M, Okinaga T, Ripley B, Mignot E, Nishino S. Hypersomnolence and increased REM sleep with low cerebrospinal fluid hypocretin level in a patient after removal of craniopharyngioma. Sleep Medicine. 6: 567-9. PMID 16084764 DOI: 10.1016/J.Sleep.2005.04.002  0.64
2005 Philipp U, Hamann H, Mecklenburg L, Nishino S, Mignot E, Günzel-Apel AR, Schmutz SM, Leeb T. Polymorphisms within the canine MLPH gene are associated with dilute coat color in dogs. Bmc Genetics. 6: 34. PMID 15960853 DOI: 10.1186/1471-2156-6-34  0.64
2005 Nevsimalova S, Vankova J, Stepanova I, Seemanova E, Mignot E, Nishino S. Hypocretin deficiency in Prader-Willi syndrome. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 12: 70-2. PMID 15613151 DOI: 10.1111/j.1468-1331.2004.00969.x  0.64
2005 Nishino S, Mignot E. Chapter 13 Narcolepsy Handbook of Clinical Neurophysiology. 6: 155-177. DOI: 10.1016/S1567-4231(09)70038-3  1
2005 Chen W, Zeitzer JM, Mignot E. The hypocretins and narcolepsy pathophysiology and diagnosis Hypocretins: Integrators of Physiological Functions. 235-254. DOI: 10.1007/0-387-25446-3_15  1
2004 Picchioni D, Mignot EJ, Harsh JR. The month-of-birth pattern in narcolepsy is moderated by cataplexy severity and may be independent of HLA-DQB1*0602. Sleep. 27: 1471-5. PMID 15683136 DOI: 10.1093/Sleep/27.8.1471  1
2004 Taheri S, Lin L, Austin D, Young T, Mignot E. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. Plos Medicine. 1: e62. PMID 15602591 DOI: 10.1371/journal.pmed.0010062  1
2004 Arnulf I, Mignot E. Sodium oxybate for excessive daytime sleepiness in narcolepsy-cataplexy. Sleep. 27: 1242-3. PMID 15586777  1
2004 Mignot E. A year in review--basic science, narcolepsy, and sleep in neurologic diseases. Sleep. 27: 1209-12. PMID 15532216  1
2004 Fromherz S, Mignot E. Narcolepsy research: past, present, and future perspectives. Archives Italiennes De Biologie. 142: 479-86. PMID 15493549  1
2004 Desarnaud F, Murillo-Rodriguez E, Lin L, Xu M, Gerashchenko D, Shiromani SN, Nishino S, Mignot E, Shiromani PJ. The diurnal rhythm of hypocretin in young and old F344 rats. Sleep. 27: 851-6. PMID 15453542 DOI: 10.1093/Sleep/27.5.851  1
2004 Lin L, Finn L, Zhang J, Young T, Mignot E. Angiotensin-converting enzyme, sleep-disordered breathing, and hypertension. American Journal of Respiratory and Critical Care Medicine. 170: 1349-53. PMID 15447944 DOI: 10.1164/rccm.200405-616OC  1
2004 Mignot E. An update on the pharmacotherapy of excessive daytime sleepiness and cataplexy. Sleep Medicine Reviews. 8: 333-8. PMID 15336234 DOI: 10.1016/j.smrv.2004.06.003  1
2004 Mignot E. Sleep, sleep disorders and hypocretin (orexin). Sleep Medicine. 5: S2-8. PMID 15301991 DOI: 10.1016/S1389-9457(04)90001-9  1
2004 Zhang S, Zeitzer JM, Yoshida Y, Wisor JP, Nishino S, Edgar DM, Mignot E. Lesions of the suprachiasmatic nucleus eliminate the daily rhythm of hypocretin-1 release. Sleep. 27: 619-27. PMID 15282996  1
2004 Baumann CR, Dauvilliers Y, Mignot E, Bassetti CL. Normal CSF hypocretin-1 (orexin A) levels in dementia with Lewy bodies associated with excessive daytime sleepiness. European Neurology. 52: 73-6. PMID 15256827 DOI: 10.1159/000079749  1
2004 Okura M, Fujiki N, Kita I, Honda K, Yoshida Y, Mignot E, Nishino S. The roles of midbrain and diencephalic dopamine cell groups in the regulation of cataplexy in narcoleptic Dobermans. Neurobiology of Disease. 16: 274-82. PMID 15207284 DOI: 10.1016/j.nbd.2004.02.008  1
2004 Castillo PR, Mignot E, Woodruff BK, Boeve BF. Undetectable CSF hypocretin-1 in "Hashimoto's encephalopathy" associated with coma. Neurology. 62: 1909. PMID 15159515  1
2004 Zeitzer JM, Buckmaster CL, Lyons DM, Mignot E. Locomotor-dependent and -independent components to hypocretin-1 (orexin A) regulation in sleep-wake consolidating monkeys. The Journal of Physiology. 557: 1045-53. PMID 15107479 DOI: 10.1113/jphysiol.2004.061606  1
2004 Overeem S, Dalmau J, Bataller L, Nishino S, Mignot E, Verschuuren J, Lammers GJ. Hypocretin-1 CSF levels in anti-Ma2 associated encephalitis. Neurology. 62: 138-40. PMID 14718718  0.64
2004 Oksenberg JR, Barcellos LF, Cree BA, Baranzini SE, Bugawan TL, Khan O, Lincoln RR, Swerdlin A, Mignot E, Lin L, Goodin D, Erlich HA, Schmidt S, Thomson G, Reich DE, et al. Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. American Journal of Human Genetics. 74: 160-7. PMID 14669136 DOI: 10.1086/380997  1
2004 Pedrazzoli M, D'Almeida V, Martins PJ, Machado RB, Ling L, Nishino S, Tufik S, Mignot E. Increased hypocretin-1 levels in cerebrospinal fluid after REM sleep deprivation. Brain Research. 995: 1-6. PMID 14644464 DOI: 10.1016/J.Brainres.2003.09.032  0.64
2004 Bourgin P, Mignot E. Hypocretins, nutrition, normal and pathological sleep Medecine Du Sommeil. 1: 17-24. DOI: 10.1016/S1769-4493(04)70163-6  1
2003 Gerashchenko D, Murillo-Rodriguez E, Lin L, Xu M, Hallett L, Nishino S, Mignot E, Shiromani PJ. Relationship between CSF hypocretin levels and hypocretin neuronal loss. Experimental Neurology. 184: 1010-6. PMID 14769395 DOI: 10.1016/S0014-4886(03)00388-1  1
2003 Fujiki N, Yoshida Y, Ripley B, Mignot E, Nishino S. Effects of IV and ICV hypocretin-1 (orexin A) in hypocretin receptor-2 gene mutated narcoleptic dogs and IV hypocretin-1 replacement therapy in a hypocretin-ligand-deficient narcoleptic dog. Sleep. 26: 953-9. PMID 14746374 DOI: 10.1093/Sleep/26.8.953  1
2003 Bassetti C, Gugger M, Bischof M, Mathis J, Sturzenegger C, Werth E, Radanov B, Ripley B, Nishino S, Mignot E. The narcoleptic borderland: a multimodal diagnostic approach including cerebrospinal fluid levels of hypocretin-1 (orexin A). Sleep Medicine. 4: 7-12. PMID 14592354 DOI: 10.1016/S1389-9457(02)00191-0  1
2003 Schenck CH, Bundlie SR, Mignot E, Mahowald MW. Normal hypocretin-1 (orexin-A) cerebrospinal fluid level in a previously reported case of severe, life-long insomnia with motor hyperactivity. Sleep Medicine. 4: 251. PMID 14592331 DOI: 10.1016/S1389-9457(02)00257-5  1
2003 Dauvilliers Y, Carlander B, Molinari N, Desautels A, Okun M, Tafti M, Montplaisir J, Mignot E, Billiard M. Month of birth as a risk factor for narcolepsy. Sleep. 26: 663-5. PMID 14572117 DOI: 10.1093/Sleep/26.6.663  1
2003 Mignot E, Chen W, Black J. On the value of measuring CSF hypocretin-1 in diagnosing narcolepsy. Sleep. 26: 646-9. PMID 14572113  1
2003 Nishino S, Kanbayashi T, Fujiki N, Uchino M, Ripley B, Watanabe M, Lammers GJ, Ishiguro H, Shoji S, Nishida Y, Overeem S, Toyoshima I, Yoshida Y, Shimizu T, Taheri S, ... Mignot E, et al. CSF hypocretin levels in Guillain-Barré syndrome and other inflammatory neuropathies. Neurology. 61: 823-5. PMID 14504329 DOI: 10.1212/01.Wnl.0000081049.14098.50  0.64
2003 Salomon RM, Ripley B, Kennedy JS, Johnson B, Schmidt D, Zeitzer JM, Nishino S, Mignot E. Diurnal variation of cerebrospinal fluid hypocretin-1 (Orexin-A) levels in control and depressed subjects. Biological Psychiatry. 54: 96-104. PMID 12873798 DOI: 10.1016/S0006-3223(02)01740-7  0.64
2003 Vankova J, Stepanova I, Jech R, Elleder M, Ling L, Mignot E, Nishino S, Nevsimalova S. Sleep disturbances and hypocretin deficiency in Niemann-Pick disease type C. Sleep. 26: 427-30. PMID 12841368  0.64
2003 Zeitzer JM, Buckmaster CL, Parker KJ, Hauck CM, Lyons DM, Mignot E. Circadian and homeostatic regulation of hypocretin in a primate model: implications for the consolidation of wakefulness. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3555-60. PMID 12716965 DOI: 10.1523/Jneurosci.23-08-03555.2003  1
2003 Marcus CL, Mignot E. Letter to the editor regarding our previous publication: "Secondary narcolepsy in children with brain tumors," SLEEP 2002; 25:435-439. Sleep. 26: 228. PMID 12683485  1
2003 Overeem S, Steens SC, Good CD, Ferrari MD, Mignot E, Frackowiak RS, van Buchem MA, Lammers GJ. Voxel-based morphometry in hypocretin-deficient narcolepsy. Sleep. 26: 44-6. PMID 12627731  1
2002 Nishino S, Mignot E. Article reviewed: Plasma orexin-A is lower in patients with narcolepsy. Sleep Medicine. 3: 377-8. PMID 14592205 DOI: 10.1016/S1389-9457(02)00078-3  1
2002 Taheri S, Mignot E. The genetics of sleep disorders. The Lancet. Neurology. 1: 242-50. PMID 12849457 DOI: 10.1016/S1474-4422(02)00103-5  1
2002 Lin L, Wisor J, Shiba T, Taheri S, Yanai K, Wurts S, Lin X, Vitaterna M, Takahashi J, Lovenberg TW, Koehl M, Uhl G, Nishino S, Mignot E. Measurement of hypocretin/orexin content in the mouse brain using an enzyme immunoassay: the effect of circadian time, age and genetic background. Peptides. 23: 2203-11. PMID 12535700 DOI: 10.1016/S0196-9781(02)00251-6  1
2002 Voderholzer U, Riemann D, Gann H, Hornyak M, Juengling F, Schumacher M, Reincke M, Von Herbay A, Nishino S, Mignot E, Berger M, Lieb K. Transient total sleep loss in cerebral Whipple's disease: a longitudinal study. Journal of Sleep Research. 11: 321-9. PMID 12464100  0.64
2002 Mignot E, Taheri S, Nishino S. Sleeping with the hypothalamus: emerging therapeutic targets for sleep disorders. Nature Neuroscience. 5: 1071-5. PMID 12403989 DOI: 10.1038/nn944  1
2002 Mignot E, Lammers GJ, Ripley B, Okun M, Nevsimalova S, Overeem S, Vankova J, Black J, Harsh J, Bassetti C, Schrader H, Nishino S. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Archives of Neurology. 59: 1553-62. PMID 12374492 DOI: 10.1001/Archneur.59.10.1553  1
2002 Merikangas KR, Chakravarti A, Moldin SO, Araj H, Blangero JC, Burmeister M, Crabbe J, Depaulo JR, Foulks E, Freimer NB, Koretz DS, Lichtenstein W, Mignot E, Reiss AL, Risch NJ, et al. Future of genetics of mood disorders research. Biological Psychiatry. 52: 457-77. PMID 12361664 DOI: 10.1016/S0006-3223(02)01471-3  1
2002 Allen RP, Mignot E, Ripley B, Nishino S, Earley CJ. Increased CSF hypocretin-1 (orexin-A) in restless legs syndrome. Neurology. 59: 639-41. PMID 12196669 DOI: 10.1212/Wnl.59.4.639  1
2002 Hong SC, Leen-Kim, Park SA, Han JH, Lee SP, Lin L, Okun M, Nishino S, Mignot E. HLA and hypocretin studies in Korean patients with narcolepsy. Sleep. 25: 440-4. PMID 12071546  0.64
2002 Shiba T, Ozu M, Yoshida Y, Mignot E, Nishino S. Hypocretin stimulates [(35)S]GTP gamma S binding in Hcrtr 2-transfected cell lines and in brain homogenate. Biochemical and Biophysical Research Communications. 294: 615-20. PMID 12056812 DOI: 10.1016/S0006-291X(02)00521-1  1
2002 Taheri S, Zeitzer JM, Mignot E. The role of hypocretins (orexins) in sleep regulation and narcolepsy. Annual Review of Neuroscience. 25: 283-313. PMID 12052911 DOI: 10.1146/annurev.neuro.25.112701.142826  1
2002 Fujiki N, Morris L, Mignot E, Nishino S. Analysis of onset location, laterality and propagation of cataplexy in canine narcolepsy. Psychiatry and Clinical Neurosciences. 56: 275-6. PMID 12047593 DOI: 10.1046/j.1440-1819.2002.00978.x  1
2002 Nishino S, Ripley B, Mignot E, Benson KL, Zarcone VP. CSF hypocretin-1 levels in schizophrenics and controls: relationship to sleep architecture. Psychiatry Research. 110: 1-7. PMID 12007588 DOI: 10.1016/S0165-1781(02)00032-X  1
2002 Overeem S, van Hilten JJ, Ripley B, Mignot E, Nishino S, Lammers GJ. Normal hypocretin-1 levels in Parkinson's disease patients with excessive daytime sleepiness. Neurology. 58: 498-9. PMID 11839864 DOI: 10.1212/Wnl.58.3.498  0.64
2002 Okun ML, Lin L, Pelin Z, Hong S, Mignot E. Clinical aspects of narcolepsy-cataplexy across ethnic groups. Sleep. 25: 27-35. PMID 11833858  1
2001 Hartwig G, Harsh J, Ripley B, Nishino S, Mignot E. Low cerebrospinal fluid hypocretin levels found in familial narcolepsy. Sleep Medicine. 2: 451-3. PMID 14592396 DOI: 10.1016/S1389-9457(01)00077-6  0.64
2001 Ripley B, Overeem S, Fujiki N, Nevsimalova S, Uchino M, Yesavage J, Di Monte D, Dohi K, Melberg A, Lammers GJ, Nishida Y, Roelandse FW, Hungs M, Mignot E, Nishino S. CSF hypocretin/orexin levels in narcolepsy and other neurological conditions. Neurology. 57: 2253-8. PMID 11756606 DOI: 10.1212/Wnl.57.12.2253  0.64
2001 Hungs M, Lin L, Okun M, Mignot E. Polymorphisms in the vicinity of the hypocretin/orexin are not associated with human narcolepsy. Neurology. 57: 1893-5. PMID 11723284  1
2001 Yoshida Y, Fujiki N, Nakajima T, Ripley B, Matsumura H, Yoneda H, Mignot E, Nishino S. Fluctuation of extracellular hypocretin-1 (orexin A) levels in the rat in relation to the light-dark cycle and sleep-wake activities. The European Journal of Neuroscience. 14: 1075-81. PMID 11683899 DOI: 10.1046/J.0953-816X.2001.01725.X  0.64
2001 Mignot E. A commentary on the neurobiology of the hypocretin/orexin system. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: S5-13. PMID 11682267 DOI: 10.1016/S0893-133X(01)00316-5  1
2001 Nishino S, Fujiki N, Ripley B, Sakurai E, Kato M, Watanabe T, Mignot E, Yanai K. Decreased brain histamine content in hypocretin/orexin receptor-2 mutated narcoleptic dogs. Neuroscience Letters. 313: 125-8. PMID 11682143 DOI: 10.1016/S0304-3940(01)02270-4  0.64
2001 Nishino S, Ripley B, Overeem S, Nevsimalova S, Lammers GJ, Vankova J, Okun M, Rogers W, Brooks S, Mignot E. Low cerebrospinal fluid hypocretin (Orexin) and altered energy homeostasis in human narcolepsy. Annals of Neurology. 50: 381-8. PMID 11558795  0.64
2001 Ripley B, Fujiki N, Okura M, Mignot E, Nishino S. Hypocretin levels in sporadic and familial cases of canine narcolepsy. Neurobiology of Disease. 8: 525-34. PMID 11442359 DOI: 10.1006/Nbdi.2001.0389  1
2001 Overeem S, Mignot E, van Dijk JG, Lammers GJ. Narcolepsy: clinical features, new pathophysiologic insights, and future perspectives. Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society. 18: 78-105. PMID 11435802  1
2001 Lin L, Hungs M, Mignot E. Narcolepsy and the HLA region. Journal of Neuroimmunology. 117: 9-20. PMID 11431000 DOI: 10.1016/S0165-5728(01)00333-2  1
2001 Scammell TE, Nishino S, Mignot E, Saper CB. Narcolepsy and low CSF orexin (hypocretin) concentration after a diencephalic stroke. Neurology. 56: 1751-3. PMID 11425947 DOI: 10.1212/Wnl.56.12.1751  1
2001 Okura M, Fujiki N, Ripley B, Takahashi S, Amitai N, Mignot E, Nishino S. Narcoleptic canines display periodic leg movements during sleep. Psychiatry and Clinical Neurosciences. 55: 243-4. PMID 11422858 DOI: 10.1046/J.1440-1819.2001.00842.X  1
2001 Li R, Faraco JH, Lin L, Lin X, Hinton L, Rogers W, Lowe JK, Ostrander EA, Mignot E. Physical and radiation hybrid mapping of canine chromosome 12, in a region corresponding to human chromosome 6p12-q12. Genomics. 73: 299-315. PMID 11350122 DOI: 10.1006/geno.2000.6487  1
2001 Hungs M, Mignot E. Hypocretin/orexin, sleep and narcolepsy. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 23: 397-408. PMID 11340621 DOI: 10.1002/bies.1058  1
2001 Mignot E. A hundred years of narcolepsy research. Archives Italiennes De Biologie. 139: 207-20. PMID 11330202  1
2001 Fujiki N, Yoshida Y, Ripley B, Honda K, Mignot E, Nishino S. Changes in CSF hypocretin-1 (orexin A) levels in rats across 24 hours and in response to food deprivation. Neuroreport. 12: 993-7. PMID 11303775 DOI: 10.1097/00001756-200104170-00026  0.64
2001 Mignot E, Thorsby E. Narcolepsy and the HLA system. The New England Journal of Medicine. 344: 692. PMID 11229347 DOI: 10.1056/NEJM200103013440918  1
2001 Wisor JP, Nishino S, Sora I, Uhl GH, Mignot E, Edgar DM. Dopaminergic role in stimulant-induced wakefulness. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1787-94. PMID 11222668  1
2001 Melberg A, Ripley B, Lin L, Hetta J, Mignot E, Nishino S. Hypocretin deficiency in familial symptomatic narcolepsy. Annals of Neurology. 49: 136-7. PMID 11198287  0.64
2001 Hartwig G, Harsh J, Ripley B, Nishino S, Mignot E. Low cerebrospinal fluid hypocretin levels found in familial narcolepsy Sleep Medicine. 2: 451-453. DOI: 10.1016/S1389-9457(01)00077-6  1
2000 Nishino S, Okura M, Mignot E. Narcolepsy: genetic predisposition and neuropharmacological mechanisms. REVIEW ARTICLE. Sleep Medicine Reviews. 4: 57-99. PMID 12531161 DOI: 10.1053/smrv.1999.0069  1
2000 Nishino S, Riehl J, Hong J, Kwan M, Reid M, Mignot E. Is narcolepsy a REM sleep disorder? Analysis of sleep abnormalities in narcoleptic Dobermans. Neuroscience Research. 38: 437-46. PMID 11164570 DOI: 10.1016/S0168-0102(00)00195-4  1
2000 Wagner JL, Storb R, Storer B, Mignot E. DLA-DQB1 alleles and bone marrow transplantation experiments in narcoleptic dogs. Tissue Antigens. 56: 223-31. PMID 11034558 DOI: 10.1034/j.1399-0039.2000.560304.x  1
2000 Okura M, Riehl J, Mignot E, Nishino S. Sulpiride, a D2/D3 blocker, reduces cataplexy but not REM sleep in canine narcolepsy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 528-38. PMID 11027918 DOI: 10.1016/S0893-133X(00)00140-8  1
2000 Kanbayashi T, Honda K, Kodama T, Mignot E, Nishino S. Implication of dopaminergic mechanisms in the wake-promoting effects of amphetamine: a study of D- and L-derivatives in canine narcolepsy. Neuroscience. 99: 651-9. PMID 10974428 DOI: 10.1016/S0306-4522(00)00239-6  1
2000 Peyron C, Faraco J, Rogers W, Ripley B, Overeem S, Charnay Y, Nevsimalova S, Aldrich M, Reynolds D, Albin R, Li R, Hungs M, Pedrazzoli M, Padigaru M, Kucherlapati M, ... ... Mignot E, et al. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nature Medicine. 6: 991-7. PMID 10973318 DOI: 10.1038/79690  1
2000 Riehl J, Honda K, Kwan M, Hong J, Mignot E, Nishino S. Chronic oral administration of CG-3703, a thyrotropin releasing hormone analog, increases wake and decreases cataplexy in canine narcolepsy. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 34-45. PMID 10869884 DOI: 10.1016/S0893-133X(99)00159-1  1
2000 Hong SC, Hayduk R, Lim J, Mignot E. Clinical and polysomnographic features in DQB1*0602 positive and negative narcolepsy patients: results from the modafinil clinical trial. Sleep Medicine. 1: 33-39. PMID 10733618 DOI: 10.1016/S1389-9457(99)00007-6  1
2000 Riehl J, Okura M, Mignot E, Nishino S. Inheritance of von Willebrand's disease in a colony of Doberman Pinschers. American Journal of Veterinary Research. 61: 115-20. PMID 10685679  1
2000 Nishino S, Ripley B, Overeem S, Lammers GJ, Mignot E. Hypocretin (orexin) deficiency in human narcolepsy. Lancet. 355: 39-40. PMID 10615891 DOI: 10.1016/S0140-6736(99)05582-8  1
2000 Hungs M, Mignot E. Pathophysiological and clinical aspects of narcolepsy: A disorder associated with hypocretin abnormalities Somnologie. 4: 111-116.  1
1999 Honda K, Riehl J, Mignot E, Nishino S. Dopamine D3 agonists into the substantia nigra aggravate cataplexy but do not modify sleep. Neuroreport. 10: 3717-24. PMID 10619672  1
1999 Nishino S, Mignot E. Drug treatment of patients with insomnia and excessive daytime sleepiness: pharmacokinetic considerations. Clinical Pharmacokinetics. 37: 305-30. PMID 10554047 DOI: 10.2165/00003088-199937040-00003  1
1999 Honda K, Riehl J, Mignot E, Nishino S. Dopamine D3 agonists into the substantia nigra aggravate cataplexy but do not modify sleep [corrected]. Neuroreport. 10: 3111-8. PMID 10549832  1
1999 Lin L, Faraco J, Li R, Kadotani H, Rogers W, Lin X, Qiu X, de Jong PJ, Nishino S, Mignot E. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell. 98: 365-76. PMID 10458611  0.64
1999 Katzenberg D, Young T, Lin L, Finn L, Mignot E. A human period gene (HPER1) polymorphism is not associated with diurnal preference in normal adults. Psychiatric Genetics. 9: 107-9. PMID 10412192  1
1999 Wu MF, Gulyani SA, Yau E, Mignot E, Phan B, Siegel JM. Locus coeruleus neurons: cessation of activity during cataplexy. Neuroscience. 91: 1389-99. PMID 10391445 DOI: 10.1016/S0306-4522(98)00600-9  0.52
1999 Mignot E, Young T, Lin L, Finn L. Nocturnal sleep and daytime sleepiness in normal subjects with HLA-DQB1*0602. Sleep. 22: 347-52. PMID 10341385  1
1999 Li R, Mignot E, Faraco J, Kadotani H, Cantanese J, Zhao B, Lin X, Hinton L, Ostrander EA, Patterson DF, de Jong PJ. Construction and characterization of an eightfold redundant dog genomic bacterial artificial chromosome library. Genomics. 58: 9-17. PMID 10331940 DOI: 10.1006/geno.1999.5772  1
1999 Anic-Labat S, Guilleminault C, Kraemer HC, Meehan J, Arrigoni J, Mignot E. Validation of a cataplexy questionnaire in 983 sleep-disorders patients. Sleep. 22: 77-87. PMID 9989368  0.52
1999 Faraco J, Lin X, Li R, Hinton L, Lin L, Mignot E. Genetic studies in narcolepsy, a disorder affecting REM sleep. The Journal of Heredity. 90: 129-32. PMID 9987919 DOI: 10.1093/jhered/90.1.129  1
1999 Siegel JM, Nienhuis R, Gulyani S, Ouyang S, Wu MF, Mignot E, Switzer RC, McMurry G, Cornford M. Neuronal degeneration in canine narcolepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 248-57. PMID 9870955  0.52
1998 Nishino S, Mao J, Sampathkumaran R, Shelton J, Mignot E. Increased dopaminergic transmission mediates the wake-promoting effects of CNS stimulants Sleep Research Online. 1: 49-61. PMID 11382857  1
1998 Nishino S, Honda K, Riehl J, Okura M, Mignot E. Neuronal activity in the cholinoceptive basal forebrain of freely moving narcoleptic dobermans. Neuroreport. 9: 3653-61. PMID 9858375  1
1998 Katzenberg D, Young T, Finn L, Lin L, King DP, Takahashi JS, Mignot E. A CLOCK polymorphism associated with human diurnal preference. Sleep. 21: 569-76. PMID 9779516 DOI: 10.1093/Sleep/21.6.569  1
1998 Riehl J, Nishino S, Cederberg R, Dement WC, Mignot E. Development of cataplexy in genetically narcoleptic Dobermans. Experimental Neurology. 152: 292-302. PMID 9710528 DOI: 10.1006/exnr.1998.6847  1
1998 Nishino S, Mignot E, Benson KL, Zarcone VP. Cerebrospinal fluid prostaglandins and corticotropin releasing factor in schizophrenics and controls: relationship to sleep architecture. Psychiatry Research. 78: 141-50. PMID 9657418 DOI: 10.1016/S0165-1781(98)00012-2  1
1998 Reid MS, Nishino S, Tafti M, Siegel JM, Dement WC, Mignot E. Neuropharmacological characterization of basal forebrain cholinergic stimulated cataplexy in narcoleptic canines. Experimental Neurology. 151: 89-104. PMID 9582257 DOI: 10.1006/Exnr.1998.6787  1
1998 Kadotani H, Faraco J, Mignot E. Genetic studies in the sleep disorder narcolepsy. Genome Research. 8: 427-34. PMID 9582188  1
1998 Mignot E, Young T, Lin L, Finn L, Palta M. Reduction of REM sleep latency associated with HLA-DQB1*0602 in normal adults. Lancet. 351: 727. PMID 9504524 DOI: 10.1016/S0140-6736(05)78496-8  1
1998 Mignot E. Genetic and familial aspects of narcolepsy. Neurology. 50: S16-22. PMID 9484418  1
1998 Guilleminault C, Heinzer R, Mignot E, Black J. Investigations into the neurologic basis of narcolepsy. Neurology. 50: S8-15. PMID 9484417  1
1998 Cederberg R, Nishino S, Dement WC, Mignot E. Breeding history of the Stanford colony of narcoleptic dogs. The Veterinary Record. 142: 31-6. PMID 9481825  1
1998 Pelin Z, Guilleminault C, Risch N, Grumet FC, Mignot E. HLA-DQB1*0602 homozygosity increases relative risk for narcolepsy but not disease severity in two ethnic groups. US Modafinil in Narcolepsy Multicenter Study Group. Tissue Antigens. 51: 96-100. PMID 9459509 DOI: 10.1111/j.1399-0039.1998.tb02952.x  1
1997 Honda K, Riehl J, Inoué S, Mignot E, Nishino S. Central administration of vitamin B12 aggravates cataplexy in canine narcolepsy. Neuroreport. 8: 3861-5. PMID 9462456  1
1997 Nevsímalová S, Mignot E, Sonka K, Arrigoni JL. Familial aspects of narcolepsy-cataplexy in the Czech Republic. Sleep. 20: 1021-6. PMID 9456468  1
1997 Mignot E, Hayduk R, Black J, Grumet FC, Guilleminault C. HLA DQB1*0602 is associated with cataplexy in 509 narcoleptic patients. Sleep. 20: 1012-20. PMID 9456467  1
1997 Lin L, Jin L, Kimura A, Carrington M, Mignot E. DQ microsatellite association studies in three ethnic groups. Tissue Antigens. 50: 507-20. PMID 9389326  1
1997 Nishino S, Tafti M, Sampathkumaran R, Dement WC, Mignot E. Circadian distribution of rest/activity in narcoleptic and control dogs: assessment with ambulatory activity monitoring. Journal of Sleep Research. 6: 120-7. PMID 9377531  1
1997 Ellis MC, Hetisimer AH, Ruddy DA, Hansen SL, Kronmal GS, McClelland E, Quintana L, Drayna DT, Aldrich MS, Mignot E. HLA class II haplotype and sequence analysis support a role for DQ in narcolepsy. Immunogenetics. 46: 410-7. PMID 9271631 DOI: 10.1007/s002510050295  1
1997 Nishino S, Arrigoni J, Shelton J, Kanbayashi T, Dement WC, Mignot E. Effects of thyrotropin-releasing hormone and its analogs on daytime sleepiness and cataplexy in canine narcolepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6401-8. PMID 9236248  1
1997 Macaubas C, Jin L, Hallmayer J, Kimura A, Mignot E. The complex mutation pattern of a microsatellite. Genome Research. 7: 635-41. PMID 9199936 DOI: 10.1101/Gr.7.6.635  1
1997 Mignot E. Genetics of narcolepsy and other sleep disorders. American Journal of Human Genetics. 60: 1289-302. PMID 9199548 DOI: 10.1086/515487  1
1997 Rogers AE, Meehan J, Guilleminault C, Grumet FC, Mignot E. HLA DR15 (DR2) and DQB1*0602 typing studies in 188 narcoleptic patients with cataplexy. Neurology. 48: 1550-6. PMID 9191765  1
1997 Nishino S, Mignot E. Pharmacological aspects of human and canine narcolepsy. Progress in Neurobiology. 52: 27-78. PMID 9185233 DOI: 10.1016/S0301-0082(96)00070-6  1
1997 Mignot E, Kimura A, Lattermann A, Lin X, Yasunaga S, Mueller-Eckhardt G, Rattazzi C, Lin L, Guilleminault C, Grumet FC, Mayer G, Dement WC, Underhill P. Extensive HLA class II studies in 58 non-DRB1*15 (DR2) narcoleptic patients with cataplexy. Tissue Antigens. 49: 329-41. PMID 9151385  1
1997 Tafti M, Nishino S, Liao W, Dement WC, Mignot E. Mesopontine organization of cholinergic and catecholaminergic cell groups in the normal and narcoleptic dog. The Journal of Comparative Neurology. 379: 185-97. PMID 9050784 DOI: 10.1002/(Sici)1096-9861(19970310)379:2<185::Aid-Cne2>3.0.Co;2-#  1
1996 Mignot E. Perspectives in narcolepsy research and therapy. Current Opinion in Pulmonary Medicine. 2: 482-7. PMID 9363189  1
1996 Jin L, Macaubas C, Hallmayer J, Kimura A, Mignot E. Mutation rate varies among alleles at a microsatellite locus: phylogenetic evidence. Proceedings of the National Academy of Sciences of the United States of America. 93: 15285-8. PMID 8986803 DOI: 10.1073/Pnas.93.26.15285  1
1996 Kanbayashi T, Nishino S, Tafti M, Hishikawa Y, Dement WC, Mignot E. Thalidomide, a hypnotic with immune modulating properties, increases cataplexy in canine narcolepsy. Neuroreport. 7: 1881-6. PMID 8905685 DOI: 10.1097/00001756-199608120-00002  1
1996 Dutra AS, Mignot E, Puck JM. Gene localization and syntenic mapping by FISH in the dog. Cytogenetics and Cell Genetics. 74: 113-7. PMID 8893815  1
1996 Reid MS, Tafti M, Nishino S, Sampathkumaran R, Siegel JM, Mignot E. Local administration of dopaminergic drugs into the ventral tegmental area modulates cataplexy in the narcoleptic canine. Brain Research. 733: 83-100. PMID 8891251 DOI: 10.1016/0006-8993(96)00541-0  1
1996 Kanbayashi T, Nishino S, Tafti M, Hishikawa Y, Dement WC, Mignot E. Thalidomide, immune modulation and narcolepsy. Sleep. 19: 116. PMID 8855033 DOI: 10.1093/Sleep/19.2.116  1
1996 Singh SM, George CF, Ott RN, Rattazzi C, Guilleminault C, Dement WC, Mignot E. IgH (mu-switch and gamma-1) region restriction fragment length polymorphism in human narcolepsy. Journal of Clinical Immunology. 16: 208-15. PMID 8840222 DOI: 10.1007/BF01541226  1
1996 Tafti M, Nishino S, Aldrich MS, Liao W, Dement WC, Mignot E. Major histocompatibility class II molecules in the CNS: increased microglial expression at the onset of narcolepsy in canine model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 4588-95. PMID 8764647 DOI: 10.1523/Jneurosci.16-15-04588.1996  1
1996 Nevšimalová S, Mignot E, Šonka K, Arrigoni JL. Some genetic aspects of narcolepsy Ceska a Slovenska Neurologie a Neurochirurgie. 59: 210-215.  1
1995 Shelton J, Nishino S, Vaught J, Dement WC, Mignot E. Comparative effects of modafinil and amphetamine on daytime sleepiness and cataplexy of narcoleptic dogs. Sleep. 18: 817-26. PMID 8746387  1
1995 Nishino S, Shelton J, Renaud A, Dement WC, Mignot E. Effect of 5-HT1A receptor agonists and antagonists on canine cataplexy. The Journal of Pharmacology and Experimental Therapeutics. 272: 1170-5. PMID 7891329  1
1995 Mignot E, Tafti M, Dement WC, Grumet FC. Narcolepsy and immunity. Advances in Neuroimmunology. 5: 23-37. PMID 7795891 DOI: 10.1016/0960-5428(94)00043-N  1
1995 Nishino S, Tafti M, Reid MS, Shelton J, Siegel JM, Dement WC, Mignot E. Muscle atonia is triggered by cholinergic stimulation of the basal forebrain: implication for the pathophysiology of canine narcolepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 4806-14. PMID 7623112 DOI: 10.1523/Jneurosci.15-07-04806.1995  1
1995 Nitz D, Andersen A, Fahringer H, Nienhuis R, Mignot E, Siegel J. Altered distribution of cholinergic cells in the narcoleptic dog. Neuroreport. 6: 1521-4. PMID 7579139 DOI: 10.1097/00001756-199507310-00014  1
1995 Behar E, Lin X, Grumet FC, Mignot E. A new DRB1*1202 allele (DRB1*12022) found in association with DQA1*0102 and DQB1*0602 in two black narcoleptic subjects. Immunogenetics. 41: 52. PMID 7528725 DOI: 10.1007/BF00188436  1
1994 Grumet FC, Mignot E. A non-DR2 narcoleptic patient with a unique DRB1-08del, DQB1-0602 haplotype having a new DRB1 allele with a codon deletion. Human Immunology. 39: 302. PMID 8071105 DOI: 10.1016/0198-8859(94)90274-7  1
1994 Reid MS, Siegel JM, Dement WC, Mignot E. Cholinergic mechanisms in canine narcolepsy--II. Acetylcholine release in the pontine reticular formation is enhanced during cataplexy. Neuroscience. 59: 523-30. PMID 8008206 DOI: 10.1016/0306-4522(94)90174-0  1
1994 Reid MS, Tafti M, Geary JN, Nishino S, Siegel JM, Dement WC, Mignot E. Cholinergic mechanisms in canine narcolepsy--I. Modulation of cataplexy via local drug administration into the pontine reticular formation. Neuroscience. 59: 511-22. PMID 8008205 DOI: 10.1016/0306-4522(94)90173-2  1
1994 Mignot E, Nishino S, Guilleminault C, Dement WC. Modafinil binds to the dopamine uptake carrier site with low affinity. Sleep. 17: 436-7. PMID 7991954  1
1994 Reid MS, Tafti M, Nishino S, Siegel JM, Dement WC, Mignot E. Cholinergic regulation of cataplexy in canine narcolepsy in the pontine reticular formation is mediated by M2 muscarinic receptors. Sleep. 17: 424-35. PMID 7991953 DOI: 10.1093/Sleep/17.5.424  1
1994 Nishino S, Reid MS, Dement WC, Mignot E. Neuropharmacology and neurochemistry of canine narcolepsy. Sleep. 17: S84-92. PMID 7701206  1
1994 Mignot E, Bell RA, Rattazzi C, Lovett M, Grumet FC, Dement WC. An immunoglobulin switchlike sequence is linked with canine narcolepsy. Sleep. 17: S68-76. PMID 7701203  1
1994 Mignot E, Lin X, Arrigoni J, Macaubas C, Olive F, Hallmayer J, Underhill P, Guilleminault C, Dement WC, Grumet FC. DQB1*0602 and DQA1*0102 (DQ1) are better markers than DR2 for narcolepsy in Caucasian and black Americans. Sleep. 17: S60-7. PMID 7701202 DOI: 10.1093/Sleep/17.Suppl_8.S60  1
1994 Guilleminault C, Mignot E, Partinen M. Controversies in the diagnosis of narcolepsy. Sleep. 17: S1-6. PMID 7701189  1
1993 Mignot EJ, Dement WC. Narcolepsy in animals and man. Equine Veterinary Journal. 25: 476-7. PMID 8275992  1
1993 Nishino S, Arrigoni J, Shelton J, Dement WC, Mignot E. Desmethyl metabolites of serotonergic uptake inhibitors are more potent for suppressing canine cataplexy than their parent compounds. Sleep. 16: 706-12. PMID 8165384  1
1992 Mignot E, Lin X, Kalil J, George C, Singh S, Billiard M, Montplaisir J, Arrigoni J, Guilleminault C, Dement WC. DQB1-0602 (DQw1) is not present in most nonDR2 Caucasian narcoleptics. Sleep. 15: 415-22. PMID 1455124 DOI: 10.1093/SLEEP/15.5.415  1
1992 Valtier D, Dement WC, Mignot E. Monoaminergic uptake in synaptosomes prepared from frozen brain tissue samples of normal and narcoleptic canines. Brain Research. 588: 115-9. PMID 1393561 DOI: 10.1016/0006-8993(92)91350-N  1
1992 Dement W, Mignot E. Can narcolepsy be eradicated in this millennium? Loss, Grief and Care. 5: 193-203. DOI: 10.1300/J132v05n03_19  1
1991 Renaud A, Nishino S, Dement WC, Guilleminault C, Mignot E. Effects of SDZ NVI-085, a putative subtype-selective alpha 1-agonist, on canine cataplexy, a disorder of rapid eye movement sleep. European Journal of Pharmacology. 205: 11-6. PMID 1687464 DOI: 10.1016/0014-2999(91)90763-G  1
1991 Mignot E, Wang C, Rattazzi C, Gaiser C, Lovett M, Guilleminault C, Dement WC, Grumet FC. Genetic linkage of autosomal recessive canine narcolepsy with a mu immunoglobulin heavy-chain switch-like segment. Proceedings of the National Academy of Sciences of the United States of America. 88: 3475-8. PMID 1673032 DOI: 10.1073/PNAS.88.8.3475  1
1991 Valtier D, Nishino S, Guilleminault C, Dement WC, Mignot E. Platelet alpha 2 adrenoceptors in human and canine narcolepsy. Biological Psychiatry. 29: 376-82. PMID 1645207 DOI: 10.1016/0006-3223(91)90223-9  1
1989 Nishino S, Mignot E, Fruhstorfer B, Dement WC, Hayaishi O. Prostaglandin E2 and its methyl ester reduce cataplexy in canine narcolepsy. Proceedings of the National Academy of Sciences of the United States of America. 86: 2483-7. PMID 2928344 DOI: 10.1073/Pnas.86.7.2483  1
1989 Guilleminault C, Mignot E, Grumet FC. FAMILIAL PATTERNS OF NARCOLEPSY The Lancet. 334: 1376-1379. PMID 2574313 DOI: 10.1016/S0140-6736(89)91977-6  1
1989 Mignot E, Bowersox SS, Maddaluno J, Dement W, Ciaranello R. Evidence for multiple [3H]prazosin binding sites in canine brain membranes. Brain Research. 486: 56-66. PMID 2541871 DOI: 10.1016/0006-8993(89)91277-8  1
1988 Mignot E, Guilleminault C, Bowersox S, Rappaport A, Dement WC. Role of central alpha-1 adrenoceptors in canine narcolepsy. The Journal of Clinical Investigation. 82: 885-94. PMID 2843574 DOI: 10.1172/JCI113694  1
1988 Mignot E, Guilleminault C, Bowersox S, Rappaport A, Dement WC. Effect of alpha 1-adrenoceptors blockade with prazosin in canine narcolepsy. Brain Research. 444: 184-8. PMID 2834022 DOI: 10.1016/0006-8993(88)90927-4  1
1987 Garcia Fajardo A, Mignot E. Implications of the serotoninergic system in depression Folia Neuropsiquiatrica. 22: 79-89.  1
1985 Mignot E, Laude D. Study of dopamine turnover by monitoring the decline of dopamine metabolites in rat CSF after α-methyl-p-tyrosine Journal of Neurochemistry. 45: 1527-1533. PMID 2864397  1
1985 Duval C, Mignot E. Effects of rat ovariectomy on CSF monoamine metabolite levels and elimination Journal of Neurochemistry. 44: 1312-1314. PMID 2579209  1
1985 Chaouloff F, Laude D, Mignot E, Kamoun P, Elghozi JL. Tryptophan and serotonin turnover rate in the brain of genetically hyperammonemic mice Neurochemistry International. 7: 143-153. DOI: 10.1016/0197-0186(85)90019-1  1
1984 Elghozi JL, Laude D, Duprat P, Mignot E. Pizotifen increases 5-HIAA urinary excretion in male healthy volunteers European Journal of Clinical Pharmacology. 27: 191-196. PMID 6209146 DOI: 10.1007/BF00544044  1
1984 Mignot E, Laude D, Elghozi JL. Kinetics of drug-induced changes in dopamine and serotonin metabolite concentrations in the CSF of the rat Journal of Neurochemistry. 42: 819-825. PMID 6198472  1
1984 Elghozi JL, Danguir J, Mignot E, Laude D. Brain amine metabolism is reflected in cerebral ventricular CSF Journal De Physiologie. 79: 531-535. PMID 6100312  1
1983 Elghozi JL, Laude D, Mignot E, Meyer P. Determination of alphamethyldopa, dihydroxyphenylacetic acid and 5-hydroxyindolacetic acid in the cerebrospinal fluid of the rat: Kinetic study European Heart Journal. 4: 31-34. PMID 6198176  1
1983 Elghozi JL, Mignot E, Le Quan-Bui KH. Probenecid sensitive pathway of elimination of dopamine and serotonin metabolites in CSF of the rat Journal of Neural Transmission. 57: 85-94. PMID 6194256 DOI: 10.1007/BF01250050  1
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