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Steven G. Van Lanen, Ph.D. - Publications

Affiliations: 
2003 Portland State University, Portland, OR, United States 
Area:
Biochemistry
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Daniel-Ivad PG, Van Lanen S, Ryan KS. Structure of the Oxygen, Pyridoxal Phosphate-Dependent Capuramycin Biosynthetic Protein Cap15. Biochemistry. PMID 37556254 DOI: 10.1021/acs.biochem.3c00216  0.502
2021 Clinger JA, Zhang Y, Liu Y, Miller MD, Hall RE, Van Lanen SG, Phillips GN, Thorson JS, Elshahawi SI. Structure and Function of a Dual Reductase-Dehydratase Enzyme System Involved in -Terphenyl Biosynthesis. Acs Chemical Biology. PMID 34763417 DOI: 10.1021/acschembio.1c00701  0.527
2020 Cui Z, Overbay J, Wang X, Liu X, Zhang Y, Bhardwaj M, Lemke A, Wiegmann D, Niro G, Thorson JS, Ducho C, Van Lanen SG. Pyridoxal-5'-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesis. Nature Chemical Biology. PMID 32483377 DOI: 10.1038/S41589-020-0548-3  0.309
2018 Cui Z, Liu X, Overbay J, Cai W, Wang X, Lemke A, Wiegmann D, Niro G, Thorson JS, Ducho C, Van Lanen SG. Enzymatic Synthesis of the Ribosylated Glycyl-Uridine Disaccharide Core of Peptidyl Nucleoside Antibiotics. The Journal of Organic Chemistry. PMID 29768920 DOI: 10.1021/Acs.Joc.8B00855  0.552
2018 Cui Z, Wang XC, Liu X, Lemke A, Koppermann S, Ducho C, Rohr J, Thorson JS, Van Lanen SG. Self-Resistance During Muraymycin Biosynthesis: A Complementary Nucleotidyltransferase and Phosphotransferase with Identical Modification Sites and Distinct Temporal Order. Antimicrobial Agents and Chemotherapy. PMID 29735559 DOI: 10.1128/Aac.00193-18  0.483
2018 Koppermann S, Cui Z, Fischer PD, Wang X, Ludwig J, Thorson JS, Van Lanen SG, Ducho C. Insights into the Target Interaction of Naturally Occurring Muraymycin Nucleoside Antibiotics. Chemmedchem. PMID 29438582 DOI: 10.1002/Cmdc.201700793  0.311
2018 Huang Y, Liu X, Cui Z, Wiegmann D, Niro G, Ducho C, Song Y, Yang Z, Van Lanen SG. Pyridoxal-5'-phosphate as an oxygenase cofactor: Discovery of a carboxamide-forming, α-amino acid monooxygenase-decarboxylase. Proceedings of the National Academy of Sciences of the United States of America. PMID 29343643 DOI: 10.1073/pnas.1718667115  0.339
2017 Goswami A, Liu X, Cai W, Wyche TP, Bugni TS, Meurillon M, Peyrottes S, Perigaud C, Nonaka K, Rohr J, Van Lanen SG. Evidence that Oxidative Dephosphorylation by the Non-heme Fe(II), α-Ketoglutarate:UMP Oxygenase Occurs by Stereospecific Hydroxylation. Febs Letters. PMID 28074470 DOI: 10.1002/1873-3468.12554  0.337
2016 Huber TD, Wang F, Singh S, Johnson BR, Zhang J, Sunkara M, Van Lanen SG, Morris AJ, Phillips GN, Thorson JS. Functional AdoMet isosteres resistant to classical AdoMet degradation pathways. Acs Chemical Biology. PMID 27351335 DOI: 10.1021/Acschembio.6B00348  0.356
2016 Liu X, Jin Y, Cai W, Green KD, Goswami A, Garneau-Tsodikova S, Nonaka K, Baba S, Funabashi M, Yang Z, Van Lanen SG. A biocatalytic approach to capuramycin analogues by exploiting a substrate permissive N-transacylase CapW. Organic & Biomolecular Chemistry. PMID 27050157 DOI: 10.1039/C6Ob00381H  0.413
2014 Singh S, Zhang J, Huber TD, Sunkara M, Hurley K, Goff RD, Wang G, Zhang W, Liu C, Rohr J, Van Lanen SG, Morris AJ, Thorson JS. Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analogues. Angewandte Chemie (International Ed. in English). 53: 3965-9. PMID 24616228 DOI: 10.1002/Anie.201308272  0.374
2013 Chi X, Baba S, Tibrewal N, Funabashi M, Nonaka K, Van Lanen SG. The muraminomicin biosynthetic gene cluster and enzymatic formation of the 2-deoxyaminoribosyl appendage. Medchemcomm. 4: 239-243. PMID 23476724 DOI: 10.1039/C2Md20245J  0.377
2012 Barnard-Britson S, Chi X, Nonaka K, Spork AP, Tibrewal N, Goswami A, Pahari P, Ducho C, Rohr J, Van Lanen SG. Amalgamation of nucleosides and amino acids in antibiotic biosynthesis: discovery of an L-threonine:uridine-5'-aldehyde transaldolase. Journal of the American Chemical Society. 134: 18514-7. PMID 23110675 DOI: 10.1021/Ja308185Q  0.433
2012 Yang Z, Unrine J, Nonaka K, Van Lanen SG. Fe(II)-dependent, uridine-5'-monophosphate α-ketoglutarate dioxygenases in the synthesis of 5'-modified nucleosides. Methods in Enzymology. 516: 153-68. PMID 23034228 DOI: 10.1016/B978-0-12-394291-3.00031-9  0.399
2012 Wang G, Pahari P, Kharel MK, Chen J, Zhu H, Van Lanen SG, Rohr J. Cooperation of two bifunctional enzymes in the biosynthesis and attachment of deoxysugars of the antitumor antibiotic mithramycin. Angewandte Chemie (International Ed. in English). 51: 10638-42. PMID 22997042 DOI: 10.1002/Anie.201205414  0.532
2012 Tibrewal N, Downey TE, Van Lanen SG, Ul Sharif E, O'Doherty GA, Rohr J. Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway. Journal of the American Chemical Society. 134: 12402-5. PMID 22800463 DOI: 10.1021/Ja305113D  0.41
2012 Pahari P, Kharel MK, Shepherd MD, van Lanen SG, Rohr J. Enzymatic total synthesis of defucogilvocarcin M and its implications for gilvocarcin biosynthesis. Angewandte Chemie (International Ed. in English). 51: 1216-20. PMID 22223167 DOI: 10.1002/Anie.201105882  0.315
2011 Chi X, Pahari P, Nonaka K, Van Lanen SG. Biosynthetic origin and mechanism of formation of the aminoribosyl moiety of peptidyl nucleoside antibiotics. Journal of the American Chemical Society. 133: 14452-9. PMID 21819104 DOI: 10.1021/Ja206304K  0.381
2010 Moon M, Van Lanen SG. Characterization of a dual specificity aryl acid adenylation enzyme with dual function in nikkomycin biosynthesis. Biopolymers. 93: 791-801. PMID 20577996 DOI: 10.1002/bip.21479  0.449
2009 Van Lanen SG, Lin S, Horsman GP, Shen B. Characterization of SgcE6, the flavin reductase component supporting FAD-dependent halogenation and hydroxylation in the biosynthesis of the enediyne antitumor antibiotic C-1027. Fems Microbiology Letters. 300: 237-41. PMID 19817865 DOI: 10.1111/J.1574-6968.2009.01802.X  0.516
2009 Lin S, Van Lanen SG, Shen B. A free-standing condensation enzyme catalyzing ester bond formation in C-1027 biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 106: 4183-8. PMID 19246381 DOI: 10.1073/Pnas.0808880106  0.315
2008 Van Lanen SG, Lin S, Shen B. Biosynthesis of the enediyne antitumor antibiotic C-1027 involves a new branching point in chorismate metabolism. Proceedings of the National Academy of Sciences of the United States of America. 105: 494-9. PMID 18182490 DOI: 10.1073/Pnas.0708750105  0.411
2007 Lee BW, Van Lanen SG, Iwata-Reuyl D. Mechanistic studies of Bacillus subtilis QueF, the nitrile oxidoreductase involved in queuosine biosynthesis. Biochemistry. 46: 12844-54. PMID 17929836 DOI: 10.1021/Bi701265R  0.708
2007 Cooke HA, Zhang J, Griffin MA, Nonaka K, Van Lanen SG, Shen B, Bruner SD. Characterization of NcsB2 as a promiscuous naphthoic acid/coenzyme A ligase integral to the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin. Journal of the American Chemical Society. 129: 7728-9. PMID 17539640 DOI: 10.1021/Ja071886A  0.339
2007 Christianson CV, Montavon TJ, Van Lanen SG, Shen B, Bruner SD. The structure of L-tyrosine 2,3-aminomutase from the C-1027 enediyne antitumor antibiotic biosynthetic pathway. Biochemistry. 46: 7205-14. PMID 17516659 DOI: 10.1021/Bi7003685  0.43
2006 Van Lanen SG, Lin S, Dorrestein PC, Kelleher NL, Shen B. Substrate specificity of the adenylation enzyme SgcC1 involved in the biosynthesis of the enediyne antitumor antibiotic C-1027. The Journal of Biological Chemistry. 281: 29633-40. PMID 16887797 DOI: 10.1074/Jbc.M605887200  0.342
2005 Swairjo MA, Reddy RR, Lee B, Van Lanen SG, Brown S, de Crécy-Lagard V, Iwata-Reuyl D, Schimmel P. Crystallization and preliminary X-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 945-8. PMID 16511203 DOI: 10.1107/S1744309105029246  0.64
2005 Van Lanen SG, Reader JS, Swairjo MA, de Crécy-Lagard V, Lee B, Iwata-Reuyl D. From cyclohydrolase to oxidoreductase: discovery of nitrile reductase activity in a common fold. Proceedings of the National Academy of Sciences of the United States of America. 102: 4264-9. PMID 15767583 DOI: 10.1073/Pnas.0408056102  0.717
2003 Van Lanen SG, Iwata-Reuyl D. Kinetic mechanism of the tRNA-modifying enzyme S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA). Biochemistry. 42: 5312-20. PMID 12731872 DOI: 10.1021/Bi034197U  0.683
2003 Van Lanen SG, Kinzie SD, Matthieu S, Link T, Culp J, Iwata-Reuyl D. tRNA modification by S-adenosylmethionine:tRNA ribosyltransferase-isomerase. Assay development and characterization of the recombinant enzyme. The Journal of Biological Chemistry. 278: 10491-9. PMID 12533518 DOI: 10.1074/Jbc.M207727200  0.702
2000 Bai Y, Fox DT, Lacy JA, Van Lanen SG, Iwata-Reuyl D. Hypermodification of tRNA in Thermophilic archaea. Cloning, overexpression, and characterization of tRNA-guanine transglycosylase from Methanococcus jannaschii. The Journal of Biological Chemistry. 275: 28731-8. PMID 10862614 DOI: 10.1074/Jbc.M002174200  0.706
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