John E. Dominy, Ph.D. - Publications

Affiliations: 
2008 Cornell University, Ithaca, NY, United States 
Area:
Nutrition, Molecular Biology

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Tavares CD, Sharabi K, Dominy JE, Lee Y, Isasa M, Orozco JM, Jedrychowski MP, Kamenecka TM, Griffin PR, Gygi SP, Puigserver P. The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyl Transferase and the PGC-1α Transcriptional Coactivator. The Journal of Biological Chemistry. PMID 27022023 DOI: 10.1074/Jbc.M115.706200  0.421
2014 Chow JD, Lawrence RT, Healy ME, Dominy JE, Liao JA, Breen DS, Byrne FL, Kenwood BM, Lackner C, Okutsu S, Mas VR, Caldwell SH, Tomsig JL, Cooney GJ, Puigserver PB, et al. Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation. Molecular Metabolism. 3: 419-31. PMID 24944901 DOI: 10.1016/J.Molmet.2014.02.004  0.376
2014 Lee Y, Dominy JE, Choi YJ, Jurczak M, Tolliday N, Camporez JP, Chim H, Lim JH, Ruan HB, Yang X, Vazquez F, Sicinski P, Shulman GI, Puigserver P. Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression. Nature. 510: 547-51. PMID 24870244 DOI: 10.1038/Nature13267  0.324
2013 Dominy J, Puigserver P, Cantó C. In vivo measurement of the acetylation state of sirtuin substrates as a proxy for sirtuin activity. Methods in Molecular Biology (Clifton, N.J.). 1077: 217-37. PMID 24014410 DOI: 10.1007/978-1-62703-637-5_15  0.41
2013 Hall JA, Dominy JE, Lee Y, Puigserver P. The sirtuin family's role in aging and age-associated pathologies. The Journal of Clinical Investigation. 123: 973-9. PMID 23454760 DOI: 10.1172/Jci64094  0.324
2013 Lim JH, Gerhart-Hines Z, Dominy JE, Lee Y, Kim S, Tabata M, Xiang YK, Puigserver P. Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex. The Journal of Biological Chemistry. 288: 7117-26. PMID 23329830 DOI: 10.1074/Jbc.M112.415729  0.411
2012 Dominy JE, Lee Y, Jedrychowski MP, Chim H, Jurczak MJ, Camporez JP, Ruan HB, Feldman J, Pierce K, Mostoslavsky R, Denu JM, Clish CB, Yang X, Shulman GI, Gygi SP, et al. The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis. Molecular Cell. 48: 900-13. PMID 23142079 DOI: 10.1016/J.Molcel.2012.09.030  0.355
2012 Dominy JE, Vazquez F, Puigserver P. Glycine decarboxylase cleaves a "malignant" metabolic path to promote tumor initiation. Cancer Cell. 21: 143-5. PMID 22340586 DOI: 10.1016/J.Ccr.2012.01.019  0.31
2011 Dominy JE, Gerhart-Hines Z, Puigserver P. Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming. Cold Spring Harbor Symposia On Quantitative Biology. 76: 203-9. PMID 22371372 DOI: 10.1101/Sqb.2012.76.010843  0.357
2011 Gerhart-Hines Z, Dominy JE, Blättler SM, Jedrychowski MP, Banks AS, Lim JH, Chim H, Gygi SP, Puigserver P. The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+). Molecular Cell. 44: 851-63. PMID 22195961 DOI: 10.1016/J.Molcel.2011.12.005  0.466
2011 Stipanuk MH, Simmons CR, Karplus PA, Dominy JE. Thiol dioxygenases: unique families of cupin proteins. Amino Acids. 41: 91-102. PMID 20195658 DOI: 10.1007/S00726-010-0518-2  0.609
2010 Dominy JE, Lee Y, Gerhart-Hines Z, Puigserver P. Nutrient-dependent regulation of PGC-1alpha's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5. Biochimica Et Biophysica Acta. 1804: 1676-83. PMID 20005308 DOI: 10.1016/J.Bbapap.2009.11.023  0.395
2009 Stipanuk MH, Ueki I, Dominy JE, Simmons CR, Hirschberger LL. Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels. Amino Acids. 37: 55-63. PMID 19011731 DOI: 10.1007/S00726-008-0202-Y  0.674
2008 Stipanuk MH, Dominy JE, Ueki I, Hirschberger LL. Measurement of Cysteine Dioxygenase Activity and Protein Abundance. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. 38: 6.15.1-6.15.25. PMID 19885389 DOI: 10.1002/0471140856.Tx0615S38  0.646
2008 Simmons CR, Krishnamoorthy K, Granett SL, Schuller DJ, Dominy JE, Begley TP, Stipanuk MH, Karplus PA. A putative Fe2+-bound persulfenate intermediate in cysteine dioxygenase. Biochemistry. 47: 11390-2. PMID 18847220 DOI: 10.1021/Bi801546N  0.588
2008 Dominy JE, Hwang J, Guo S, Hirschberger LL, Zhang S, Stipanuk MH. Synthesis of amino acid cofactor in cysteine dioxygenase is regulated by substrate and represents a novel post-translational regulation of activity. The Journal of Biological Chemistry. 283: 12188-201. PMID 18308719 DOI: 10.1074/Jbc.M800044200  0.678
2008 Lee JI, Dominy JE, Sikalidis AK, Hirschberger LL, Wang W, Stipanuk MH. HepG2/C3A cells respond to cysteine deprivation by induction of the amino acid deprivation/integrated stress response pathway. Physiological Genomics. 33: 218-29. PMID 18285520 DOI: 10.1152/Physiolgenomics.00263.2007  0.683
2007 Dominy JE, Simmons CR, Hirschberger LL, Hwang J, Coloso RM, Stipanuk MH. Discovery and characterization of a second mammalian thiol dioxygenase, cysteamine dioxygenase. The Journal of Biological Chemistry. 282: 25189-98. PMID 17581819 DOI: 10.1074/Jbc.M703089200  0.673
2007 Dominy JE, Hwang J, Stipanuk MH. Overexpression of cysteine dioxygenase reduces intracellular cysteine and glutathione pools in HepG2/C3A cells. American Journal of Physiology. Endocrinology and Metabolism. 293: E62-9. PMID 17327371 DOI: 10.1152/Ajpendo.00053.2007  0.665
2006 Dominy JE, Hirschberger LL, Coloso RM, Stipanuk MH. In vivo regulation of cysteine dioxygenase via the ubiquitin-26S proteasome system. Advances in Experimental Medicine and Biology. 583: 37-47. PMID 17153587 DOI: 10.1007/978-0-387-33504-9_4  0.613
2006 Coloso RM, Hirschberger LL, Dominy JE, Lee JI, Stipanuk MH. Cysteamine dioxygenase: evidence for the physiological conversion of cysteamine to hypotaurine in rat and mouse tissues. Advances in Experimental Medicine and Biology. 583: 25-36. PMID 17153586 DOI: 10.1007/978-0-387-33504-9_3  0.677
2006 Dominy JE, Simmons CR, Karplus PA, Gehring AM, Stipanuk MH. Identification and characterization of bacterial cysteine dioxygenases: a new route of cysteine degradation for eubacteria. Journal of Bacteriology. 188: 5561-9. PMID 16855246 DOI: 10.1128/Jb.00291-06  0.679
2006 Stipanuk MH, Dominy JE, Lee JI, Coloso RM. Mammalian cysteine metabolism: new insights into regulation of cysteine metabolism. The Journal of Nutrition. 136: 1652S-1659S. PMID 16702335 DOI: 10.1093/Jn/136.6.1652S  0.749
2006 Stipanuk MH, Dominy JE. Surprising insights that aren't so surprising in the modeling of sulfur amino acid metabolism. Amino Acids. 30: 251-6. PMID 16680556 DOI: 10.1007/S00726-005-0288-4  0.634
2006 Dominy JE, Hirschberger LL, Coloso RM, Stipanuk MH. Regulation of cysteine dioxygenase degradation is mediated by intracellular cysteine levels and the ubiquitin-26 S proteasome system in the living rat. The Biochemical Journal. 394: 267-73. PMID 16262602 DOI: 10.1042/Bj20051510  0.662
2004 Dominy JE, Stipanuk MH. New roles for cysteine and transsulfuration enzymes: production of H2S, a neuromodulator and smooth muscle relaxant. Nutrition Reviews. 62: 348-53. PMID 15497768 DOI: 10.1111/J.1753-4887.2004.Tb00060.X  0.578
2004 Dominy J, Thinschmidt JS, Peris J, Dawson R, Papke RL. Taurine-induced long-lasting potentiation in the rat hippocampus shows a partial dissociation from total hippocampal taurine content and independence from activation of known taurine transporters. Journal of Neurochemistry. 89: 1195-205. PMID 15147512 DOI: 10.1111/J.1471-4159.2004.02410.X  0.329
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