Bobby Thomas, PhD - Publications

Affiliations: 
Neurology Cornell University, Ithaca, NY, United States 

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Tapias V, Jainuddin S, Ahuja M, Stack C, Elipenahli C, Vignisse J, Gerges M, Starkova N, Xu H, Starkov AA, Bettendorff L, Hushpulian DM, Smirnova NA, Gazaryan IG, Kaidery NA, ... ... Thomas B, et al. Benfotiamine Treatment Activates the Nrf2/ARE Pathway and is Neuroprotective in a Transgenic Mouse Model of Tauopathy. Human Molecular Genetics. PMID 29860433 DOI: 10.1093/hmg/ddy201  1
2018 Gaisina IN, Lee SH, Kaidery NA, Ben Aissa M, Ahuja M, Smirnova NN, Wakade S, Gaisin A, Bourassa MW, Ratan RR, Nikulin SV, Poloznikov AA, Thomas B, Thatcher GRJ, Gazaryan IG. Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors. Acs Chemical Neuroscience. PMID 29338172 DOI: 10.1021/acschemneuro.7b00435  0.6
2017 Osipyants AI, Poloznikov AA, Smirnova NA, Hushpulian DM, Khristichenko AY, Chubar TA, Zakhariants AA, Ahuja M, Gaisina IN, Thomas B, Brown AM, Gazaryan IG, Tishkov VI. L-ascorbic acid: a true substrate for HIF proly hydroxylase? Biochimie. PMID 29289682 DOI: 10.1016/j.biochi.2017.12.011  0.6
2016 Smirnova NA, Kaidery NA, Hushpulian DM, Rakhman II, Poloznikov AA, Tishkov VI, Karuppagounder SS, Gaisina IN, Pekcec A, Leyen KV, Kazakov SV, Yang L, Thomas B, Ratan RR, Gazaryan IG. Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson's Disease. Aging and Disease. 7: 745-762. PMID 28053825 DOI: 10.14336/AD.2016.0505  0.6
2016 Ahuja M, Ammal Kaidery N, Yang L, Calingasan N, Smirnova N, Gaisin A, Gaisina IN, Gazaryan I, Hushpulian DM, Kaddour-Djebbar I, Bollag WB, Morgan JC, Ratan RR, Starkov AA, Beal MF, ... Thomas B, et al. Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 6332-51. PMID 27277809 DOI: 10.1523/JNEUROSCI.0426-16.2016  1
2016 Banerjee R, Kaidery NA, Thomas B. Oxidative stress in Parkinson's disease: Role in neurodegeneration and targets for therapeutics Acs Symposium Series. 1200: 147-176. DOI: 10.1021/bk-2015-1200.ch005  1
2015 Gao J, Naughton SX, Wulff H, Singh V, Beck WD, Magrane J, Thomas B, Ammal Kaidery N, Hernandez CM, Terry AV. Diisopropylfluorophosphate impairs the transport of membrane bound organelles in rat cortical axons. The Journal of Pharmacology and Experimental Therapeutics. PMID 26718240 DOI: 10.1124/jpet.115.230839  1
2014 Stack C, Jainuddin S, Elipenahli C, Gerges M, Starkova N, Starkov AA, Jové M, Portero-Otin M, Launay N, Pujol A, Kaidery NA, Thomas B, Tampellini D, Beal MF, Dumont M. Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity. Human Molecular Genetics. 23: 3716-32. PMID 24556215 DOI: 10.1093/hmg/ddu080  1
2013 Naskar A, Manivasagam T, Chakraborty J, Singh R, Thomas B, Dhanasekaran M, Mohanakumar KP. Melatonin synergizes with low doses of L-DOPA to improve dendritic spine density in the mouse striatum in experimental Parkinsonism. Journal of Pineal Research. 55: 304-12. PMID 23952687 DOI: 10.1111/jpi.12076  1
2013 Hou YJ, Banerjee R, Thomas B, Nathan C, García-Sastre A, Ding A, Uccellini MB. SARM is required for neuronal injury and cytokine production in response to central nervous system viral infection. Journal of Immunology (Baltimore, Md. : 1950). 191: 875-83. PMID 23749635 DOI: 10.4049/jimmunol.1300374  1
2013 Kaidery NA, Banerjee R, Yang L, Smirnova NA, Hushpulian DM, Liby KT, Williams CR, Yamamoto M, Kensler TW, Ratan RR, Sporn MB, Beal MF, Gazaryan IG, Thomas B. Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease. Antioxidants & Redox Signaling. 18: 139-57. PMID 22746536 DOI: 10.1089/ars.2011.4491  1
2012 Murray CJ, Vos T, Lozano R, Naghavi M, Flaxman AD, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn SY, ... ... Thomas B, et al. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 380: 2197-223. PMID 23245608 DOI: 10.1016/S0140-6736(12)61689-4  1
2012 Thomas B, Banerjee R, Starkova NN, Zhang SF, Calingasan NY, Yang L, Wille E, Lorenzo BJ, Ho DJ, Beal MF, Starkov A. Mitochondrial permeability transition pore component cyclophilin D distinguishes nigrostriatal dopaminergic death paradigms in the MPTP mouse model of Parkinson's disease. Antioxidants & Redox Signaling. 16: 855-68. PMID 21529244 DOI: 10.1089/ars.2010.3849  1
2011 Chinopoulos C, Zhang SF, Thomas B, Ten V, Starkov AA. Isolation and functional assessment of mitochondria from small amounts of mouse brain tissue. Methods in Molecular Biology (Clifton, N.J.). 793: 311-24. PMID 21913109 DOI: 10.1007/978-1-61779-328-8_20  0.56
2011 Thomas B, Beal MF. Molecular insights into Parkinson's disease. F1000 Medicine Reports. 3: 7. PMID 21655332 DOI: 10.3410/M3-7  1
2011 Ramonet D, Daher JP, Lin BM, Stafa K, Kim J, Banerjee R, Westerlund M, Pletnikova O, Glauser L, Yang L, Liu Y, Swing DA, Beal MF, Troncoso JC, McCaffery JM, ... ... Thomas B, et al. Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2. Plos One. 6: e18568. PMID 21494637 DOI: 10.1371/journal.pone.0018568  1
2011 Thomas B, Mandir AS, West N, Liu Y, Andrabi SA, Stirling W, Dawson VL, Dawson TM, Lee MK. Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation. Plos One. 6: e16706. PMID 21304957 DOI: 10.1371/journal.pone.0016706  1
2010 Banerjee R, Beal MF, Thomas B. Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications. Trends in Neurosciences. 33: 541-9. PMID 20947179 DOI: 10.1016/j.tins.2010.09.001  1
2010 Yin F, Dumont M, Banerjee R, Ma Y, Li H, Lin MT, Beal MF, Nathan C, Thomas B, Ding A. Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 4639-47. PMID 20667979 DOI: 10.1096/fj.10-161471  1
2010 Thomas B, Beal MF. Mitochondrial therapies for Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 25: S155-60. PMID 20187246 DOI: 10.1002/mds.22781  1
2010 Yin F, Banerjee R, Thomas B, Zhou P, Qian L, Jia T, Ma X, Ma Y, Iadecola C, Beal MF, Nathan C, Ding A. Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice. The Journal of Experimental Medicine. 207: 117-28. PMID 20026663 DOI: 10.1084/jem.20091568  1
2009 Andres-Mateos E, Mejias R, Sasaki M, Li X, Lin BM, Biskup S, Zhang L, Banerjee R, Thomas B, Yang L, Liu G, Beal MF, Huso DL, Dawson TM, Dawson VL. Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15846-50. PMID 20016100 DOI: 10.1523/JNEUROSCI.4357-09.2009  1
2009 Daher JP, Ying M, Banerjee R, McDonald RS, Hahn MD, Yang L, Flint Beal M, Thomas B, Dawson VL, Dawson TM, Moore DJ. Conditional transgenic mice expressing C-terminally truncated human alpha-synuclein (alphaSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons. Molecular Neurodegeneration. 4: 34. PMID 19630976 DOI: 10.1186/1750-1326-4-34  1
2009 Yang L, Calingasan NY, Thomas B, Chaturvedi RK, Kiaei M, Wille EJ, Liby KT, Williams C, Royce D, Risingsong R, Musiek ES, Morrow JD, Sporn M, Beal MF. Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription. Plos One. 4: e5757. PMID 19484125 DOI: 10.1371/journal.pone.0005757  1
2009 Banerjee R, Starkov AA, Beal MF, Thomas B. Mitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis. Biochimica Et Biophysica Acta. 1792: 651-63. PMID 19059336 DOI: 10.1016/j.bbadis.2008.11.007  1
2008 Sen N, Hara MR, Kornberg MD, Cascio MB, Bae BI, Shahani N, Thomas B, Dawson TM, Dawson VL, Snyder SH, Sawa A. Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis. Nature Cell Biology. 10: 866-73. PMID 18552833 DOI: 10.1038/ncb1747  1
2008 Habib SL, Michel D, Masliah E, Thomas B, Ko HS, Dawson TM, Abboud H, Clark RA, Imam SZ. Role of tuberin in neuronal degeneration. Neurochemical Research. 33: 1113-6. PMID 18320306 DOI: 10.1007/s11064-007-9558-8  1
2008 Banerjee R, Saravanan KS, Thomas B, Sindhu KM, Mohanakumar KP. Evidence for hydroxyl radical scavenging action of nitric oxide donors in the protection against 1-methyl-4-phenylpyridinium-induced neurotoxicity in rats. Neurochemical Research. 33: 985-95. PMID 17763941 DOI: 10.1007/s11064-007-9473-z  0.56
2007 Thomas B, Beal MF. Parkinson's disease. Human Molecular Genetics. 16: R183-94. PMID 17911161 DOI: 10.1093/hmg/ddm159  1
2007 Andres-Mateos E, Perier C, Zhang L, Blanchard-Fillion B, Greco TM, Thomas B, Ko HS, Sasaki M, Ischiropoulos H, Przedborski S, Dawson TM, Dawson VL. DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Proceedings of the National Academy of Sciences of the United States of America. 104: 14807-12. PMID 17766438 DOI: 10.1073/pnas.0703219104  1
2007 Thomas B, von Coelln R, Mandir AS, Trinkaus DB, Farah MH, Leong Lim K, Calingasan NY, Flint Beal M, Dawson VL, Dawson TM. MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity. Neurobiology of Disease. 26: 312-22. PMID 17336077 DOI: 10.1016/j.nbd.2006.12.021  1
2006 von Coelln R, Thomas B, Andrabi SA, Lim KL, Savitt JM, Saffary R, Stirling W, Bruno K, Hess EJ, Lee MK, Dawson VL, Dawson TM. Inclusion body formation and neurodegeneration are parkin independent in a mouse model of alpha-synucleinopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3685-96. PMID 16597723 DOI: 10.1523/JNEUROSCI.0414-06.2006  1
2006 Hara MR, Thomas B, Cascio MB, Bae BI, Hester LD, Dawson VL, Dawson TM, Sawa A, Snyder SH. Neuroprotection by pharmacologic blockade of the GAPDH death cascade. Proceedings of the National Academy of Sciences of the United States of America. 103: 3887-9. PMID 16505364 DOI: 10.1073/pnas.0511321103  1
2005 Wang C, Ko HS, Thomas B, Tsang F, Chew KC, Tay SP, Ho MW, Lim TM, Soong TW, Pletnikova O, Troncoso J, Dawson VL, Dawson TM, Lim KL. Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function. Human Molecular Genetics. 14: 3885-97. PMID 16278233 DOI: 10.1093/hmg/ddi413  1
2005 Zhang L, Shimoji M, Thomas B, Moore DJ, Yu SW, Marupudi NI, Torp R, Torgner IA, Ottersen OP, Dawson TM, Dawson VL. Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis. Human Molecular Genetics. 14: 2063-73. PMID 15944198 DOI: 10.1093/hmg/ddi211  1
2004 Von Coelln R, Thomas B, Savitt JM, Lim KL, Sasaki M, Hess EJ, Dawson VL, Dawson TM. Loss of locus coeruleus neurons and reduced startle in parkin null mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 10744-9. PMID 15249681 DOI: 10.1073/pnas.0401297101  1
2004 Chung KK, Thomas B, Li X, Pletnikova O, Troncoso JC, Marsh L, Dawson VL, Dawson TM. S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function. Science (New York, N.Y.). 304: 1328-31. PMID 15105460 DOI: 10.1126/science.1093891  1
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