Christopher F. Basler - Publications

Affiliations: 
Microbiology Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Microbiology Biology

177 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Davey R, Donahue C, Kesari A, Thakur N, Wang L, Hulsey-Stubbs S, Williams C, Kirby C, Leung D, Aryal U, Basler C, LaCount D. A protein-proximity screen reveals Ebola virus co-opts the mRNA decapping complex through the scaffold protein EDC4. Research Square. PMID 38352529 DOI: 10.21203/rs.3.rs-3838220/v1  0.357
2023 Vogel OA, Forwood JK, Leung DW, Amarasinghe GK, Basler CF. Viral Targeting of Importin Alpha-Mediated Nuclear Import to Block Innate Immunity. Cells. 13. PMID 38201275 DOI: 10.3390/cells13010071  0.396
2023 Haas KM, McGregor MJ, Bouhaddou M, Polacco BJ, Kim EY, Nguyen TT, Newton BW, Urbanowski M, Kim H, Williams MAP, Rezelj VV, Hardy A, Fossati A, Stevenson EJ, Sukerman E, ... ... Basler CF, et al. Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets. Nature Communications. 14: 6030. PMID 37758692 DOI: 10.1038/s41467-023-41442-z  0.412
2023 Donnelly CM, Vogel OA, Edwards MR, Taylor PE, Roby JA, Forwood JK, Basler CF. Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism. Viruses. 15. PMID 37376602 DOI: 10.3390/v15061302  0.301
2023 Ramanathan P, Tigabu B, Santos RI, Ilinykh PA, Kuzmina N, Vogel OA, Thakur N, Ahmed H, Wu C, Amarasinghe GK, Basler CF, Bukreyev A. Ebolavirus Species-Specific Interferon Antagonism Mediated by VP24. Viruses. 15. PMID 37243162 DOI: 10.3390/v15051075  0.445
2023 Jayaprakash AD, Ronk AJ, Prasad AN, Covington MF, Stein KR, Schwarz TM, Hekmaty S, Fenton KA, Geisbert TW, Basler CF, Bukreyev A, Sachidanandam R. Marburg and Ebola Virus Infections Elicit a Complex, Muted Inflammatory State in Bats. Viruses. 15. PMID 36851566 DOI: 10.3390/v15020350  0.335
2022 Edwards MR, Vogel OA, Mori H, Davey RA, Basler CF. Marburg Virus VP30 Is Required for Transcription Initiation at the Glycoprotein Gene. Mbio. e0224322. PMID 35997284 DOI: 10.1128/mbio.02243-22  0.381
2022 Munasinghe TS, Edwards MR, Tsimbalyuk S, Vogel OA, Smith KM, Stewart M, Foster JK, Bosence LA, Aragão D, Roby JA, Basler CF, Forwood JK. MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity. Nature Communications. 13: 1604. PMID 35338144 DOI: 10.1038/s41467-022-28851-2  0.329
2021 Kuzmin IV, Ramanathan P, Basler CF, Bukreyev A. Effects of Overexpression of the Egyptian Fruit Bat Innate Immune Genes on Filovirus Infections in the Host Cells. Frontiers in Virology. 1. PMID 36237518 DOI: 10.3389/fviro.2021.759655  0.362
2021 Khadka S, Williams CG, Sweeney-Gibbons J, Basler CF. 3' untranslated regions of Marburg and Ebola virus mRNAs possess negative regulators of translation that are modulated by ADAR1 editing. Journal of Virology. JVI0065221. PMID 34346762 DOI: 10.1128/JVI.00652-21  0.303
2021 Batra J, Mori H, Small GI, Anantpadma M, Shtanko O, Mishra N, Zhang M, Liu D, Williams CG, Biedenkopf N, Becker S, Gross ML, Leung DW, Davey RA, Amarasinghe GK, ... ... Basler CF, et al. Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection. The Embo Journal. e105658. PMID 34260076 DOI: 10.15252/embj.2020105658  0.428
2021 Gibbons JS, Khadka S, Williams CG, Wang L, Schneller SW, Liu C, Tufariello JM, Basler CF. Mechanisms of anti-vesicular stomatitis virus activity of deazaneplanocin and its 3-brominated analogues. Antiviral Research. 105088. PMID 34019950 DOI: 10.1016/j.antiviral.2021.105088  0.381
2021 Pei J, Wagner ND, Zou AJ, Chatterjee S, Borek D, Cole AR, Kim PJ, Basler CF, Otwinowski Z, Gross ML, Amarasinghe GK, Leung DW. Structural basis for IFN antagonism by human respiratory syncytial virus nonstructural protein 2. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33649232 DOI: 10.1073/pnas.2020587118  0.456
2021 Pinski A, Woolsey C, Jankeel A, Cross R, Basler CF, Geisbert T, Messaoudi I. Transcriptional analysis of lymphoid tissues from infected nonhuman primates reveals the basis for attenuation and immunogenicity of an Ebola virus encoding a mutant VP35 protein. Journal of Virology. PMID 33408171 DOI: 10.1128/JVI.01995-20  0.348
2020 Keiffer TR, Ciancanelli MJ, Edwards MR, Basler CF. Interactions of the Nipah Virus P, V, and W Proteins across the STAT Family of Transcription Factors. Msphere. 5. PMID 33328346 DOI: 10.1128/mSphere.00449-20  0.744
2020 Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, ... ... Basler CF, et al. Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science (New York, N.Y.). PMID 33060197 DOI: 10.1126/science.abe9403  0.308
2020 Luthra P, Anantpadma M, De S, Sourimant J, Davey RA, Plemper RK, Basler CF. High throughput screening assay to identify small molecule inhibitors of Marburg virus VP40 protein. Acs Infectious Diseases. PMID 32870648 DOI: 10.1021/Acsinfecdis.0C00512  0.455
2020 Jureka AS, Silvas JA, Basler CF. Propagation, Inactivation, and Safety Testing of SARS-CoV-2. Viruses. 12. PMID 32517266 DOI: 10.3390/V12060622  0.487
2020 Edwards MR, Hoad M, Tsimbalyuk S, Menicucci AR, Messaoudi I, Forwood JK, Basler CF. Henipavirus W proteins interact with 14-3-3 to modulate host gene expression. Journal of Virology. PMID 32321809 DOI: 10.1128/Jvi.00373-20  0.502
2020 Williams CG, Gibbons JS, Keiffer TR, Luthra P, Edwards MR, Basler CF. Impact of Měnglà virus proteins on human and bat innate immune pathways. Journal of Virology. PMID 32295912 DOI: 10.1128/Jvi.00191-20  0.593
2020 Satterfield BA, Cross RW, Fenton KA, Borisevich V, Agans KN, Deer DJ, Graber J, Basler CF, Geisbert TW, Mire CE. Correction for Satterfield et al., "Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets". Journal of Virology. 94. PMID 32234799 DOI: 10.1128/Jvi.00059-20  0.353
2020 Edwards MR, Liu G, De S, Sourimant J, Pietzsch C, Johnson B, Amarasinghe GK, Leung DW, Bukreyev A, Plemper RK, Aron Z, Bowlin TL, Moir DT, Basler CF. Small molecule compounds that inhibit antioxidant response gene expression in an inducer-dependent manner. Acs Infectious Diseases. PMID 31899866 DOI: 10.1021/Acsinfecdis.9B00416  0.335
2019 Prasad AN, Ronk AJ, Widen SG, Wood TG, Basler CF, Bukreyev A. Ebola virus produces discrete small non-coding RNAs independent of the host microRNA pathway and which lack RNA interference activity in bat and human cells. Journal of Virology. PMID 31852785 DOI: 10.1128/Jvi.01441-19  0.342
2019 Satterfield BA, Borisevich V, Foster SL, Rodriguez SE, Cross RW, Fenton KA, Agans KN, Basler CF, Geisbert TW, Mire CE. Antagonism of STAT1 by Nipah virus P gene products modulates disease course but not lethal outcome in the ferret model. Scientific Reports. 9: 16710. PMID 31723221 DOI: 10.1038/S41598-019-53037-0  0.484
2019 Woolsey C, Menicucci AR, Cross RW, Luthra P, Agans KN, Borisevich V, Geisbert JB, Mire CE, Fenton KA, Jankeel A, Anand S, Ebihara H, Geisbert TW, Messaoudi I, Basler CF. A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge. Cell Reports. 28: 3032-3046.e6. PMID 31533029 DOI: 10.1016/J.Celrep.2019.08.047  0.502
2019 Amatya P, Wagner N, Chen G, Luthra P, Shi L, Borek D, Pavlenco A, Rohrs HW, Basler CF, Sidhu SS, Gross ML, Leung DW. Marburg virus RNA synthesis is inhibited by a synthetic anti-VP35 antibody. Acs Infectious Diseases. PMID 31120240 DOI: 10.1021/ACSINFECDIS.9B00091  0.497
2019 Kuhn JH, Amarasinghe GK, Basler CF, Bavari S, Bukreyev A, Chandran K, Crozier I, Dolnik O, Dye JM, Formenty PBH, Griffiths A, Hewson R, Kobinger GP, Leroy EM, Mühlberger E, et al. ICTV Virus Taxonomy Profile: Filoviridae. The Journal of General Virology. PMID 31021739 DOI: 10.1099/Jgv.0.001252  0.462
2019 Edwards MR, Basler CF. Current status of small molecule drug development for Ebola virus and other filoviruses. Current Opinion in Virology. 35: 42-56. PMID 31003196 DOI: 10.1016/J.Coviro.2019.03.001  0.483
2018 Basler CF, Krogan NJ, Leung DW, Amarasinghe GK. Virus and host interactions critical for filoviral RNA synthesis as therapeutic targets. Antiviral Research. PMID 30550800 DOI: 10.1016/J.Antiviral.2018.12.006  0.535
2018 Batra J, Hultquist JF, Liu D, Shtanko O, Von Dollen J, Satkamp L, Jang GM, Luthra P, Schwarz TM, Small GI, Arnett E, Anantpadma M, Reyes A, Leung DW, Kaake R, ... ... Basler CF, et al. Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication. Cell. 175: 1917-1930.e13. PMID 30550789 DOI: 10.1016/J.Cell.2018.08.044  0.512
2018 Smith KM, Tsimbalyuk S, Edwards MR, Cross EM, Batra J, Soares da Costa TP, Aragão D, Basler CF, Forwood JK. Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nature Communications. 9: 3703. PMID 30209309 DOI: 10.1038/S41467-018-05928-5  0.368
2018 Luthra P, Naidoo J, Pietzsch CA, De S, Khadka S, Anantpadma M, Williams CG, Edwards MR, Davey RA, Bukreyev A, Ready JM, Basler CF. Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses. Antiviral Research. PMID 30144461 DOI: 10.1016/J.Antiviral.2018.08.012  0.521
2018 Edwards MR, Liu H, Shabman RS, Ginell GM, Luthra P, Ramanan P, Keefe LJ, Köllner B, Amarasinghe GK, Taylor DJ, Leung DW, Basler CF. Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes. Cell Reports. 24: 861-872.e6. PMID 30044983 DOI: 10.1016/J.Celrep.2018.06.045  0.508
2018 Fink SL, Vojtech L, Wagoner J, Slivinski NSJ, Jackson KJ, Wang R, Khadka S, Luthra P, Basler CF, Polyak SJ. The Antiviral Drug Arbidol Inhibits Zika Virus. Scientific Reports. 8: 8989. PMID 29895962 DOI: 10.1038/S41598-018-27224-4  0.494
2018 Su Z, Wu C, Shi L, Luthra P, Pintilie GD, Johnson B, Porter JR, Ge P, Chen M, Liu G, Frederick TE, Binning JM, Bowman GR, Zhou ZH, Basler CF, et al. Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly. Cell. 172: 966-978.e12. PMID 29474922 DOI: 10.1016/J.Cell.2018.02.009  0.41
2017 Luthra P, Liang J, Pietzsch CA, Khadka S, Edwards MR, Wei S, De S, Posner B, Bukreyev A, Ready JM, Basler CF. A high throughput screen identifies benzoquinoline compounds as inhibitors of Ebola virus replication. Antiviral Research. PMID 29294299 DOI: 10.1016/J.Antiviral.2017.12.019  0.467
2017 Rizk MG, Basler CF, Guatelli J. Cooperation of the Ebola proteins VP40 and GP1,2 with BST2 to activate NF-κβ independently of virus-like particle trapping. Journal of Virology. PMID 28878074 DOI: 10.1128/Jvi.01308-17  0.525
2017 Olejnik J, Hume AJ, Leung DW, Amarasinghe GK, Basler CF, Mühlberger E. Filovirus Strategies to Escape Antiviral Responses. Current Topics in Microbiology and Immunology. PMID 28685291 DOI: 10.1007/82_2017_13  0.472
2017 Bharaj P, Atkins C, Luthra P, Giraldo MI, Dawes BE, Miorin L, Johnson JR, Krogan NJ, Basler CF, Freiberg AN, Rajsbaum R. The host E3-Ubiquitin ligase TRIM6 ubiquitinates the Ebola virus VP35 protein and promotes virus replication. Journal of Virology. PMID 28679761 DOI: 10.1128/Jvi.00833-17  0.573
2017 Chatterjee S, Luthra P, Esaulova E, Agapov E, Yen BC, Borek DM, Edwards MR, Mittal A, Jordan DS, Ramanan P, Moore ML, Pappu RV, Holtzman MJ, Artyomov MN, Basler CF, et al. Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses. Nature Microbiology. 2: 17101. PMID 28665409 DOI: 10.1038/Nmicrobiol.2017.101  0.504
2017 Dilley KA, Voorhies AA, Luthra P, Puri V, Stockwell TB, Lorenzi H, Basler CF, Shabman RS. The Ebola virus VP35 protein binds viral immunostimulatory and host RNAs identified through deep sequencing. Plos One. 12: e0178717. PMID 28636653 DOI: 10.1371/Journal.Pone.0178717  0.496
2017 Xu W, Luthra P, Wu C, Batra J, Leung DW, Basler CF, Amarasinghe GK. Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis. Nature Communications. 8: 15576. PMID 28593988 DOI: 10.1038/Ncomms15576  0.496
2017 Duehr J, Wohlbold TJ, Oestereich L, Chromikova V, Amanat F, Rajendran M, Gomez-Medina S, Mena I, TenOever BR, García-Sastre A, Basler CF, Munoz-Fontela C, Krammer F. Novel cross-reactive monoclonal antibodies against Ebolavirus glycoproteins show protection in a murine challenge model. Journal of Virology. PMID 28592526 DOI: 10.1128/Jvi.00652-17  0.328
2017 Luthra P, Basler CF. Assays to Measure Suppression of Type I Interferon Responses by Filovirus VP35 Proteins. Methods in Molecular Biology (Clifton, N.J.). 1628: 133-142. PMID 28573616 DOI: 10.1007/978-1-4939-7116-9_10  0.547
2017 Basler CF. Molecular pathogenesis of viral hemorrhagic fever. Seminars in Immunopathology. PMID 28555386 DOI: 10.1007/S00281-017-0637-X  0.508
2017 Luthra P, Aguirre S, Yen BC, Pietzsch CA, Sanchez-Aparicio MT, Tigabu B, Morlock LK, García-Sastre A, Leung DW, Williams NS, Fernandez-Sesma A, Bukreyev A, Basler CF. Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion. Mbio. 8. PMID 28377530 DOI: 10.1128/Mbio.00368-17  0.554
2017 Aguirre S, Luthra P, Sanchez-Aparicio MT, Maestre AM, Patel J, Lamothe F, Fredericks AC, Tripathi S, Zhu T, Pintado-Silva J, Webb LG, Bernal-Rubio D, Solovyov A, Greenbaum B, Simon V, ... Basler CF, et al. Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection. Nature Microbiology. 2: 17037. PMID 28346446 DOI: 10.1038/Nmicrobiol.2017.37  0.412
2017 Basler CF. West African Ebola Virus Strains: Unstable and Ready to Invade? Cell Host & Microbe. 21: 316-318. PMID 28279342 DOI: 10.1016/J.Chom.2017.02.017  0.463
2017 Liu G, Nash PJ, Johnson B, Pietzsch C, Ilagan MG, Bukreyev A, Basler CF, Bowlin TL, Moir DT, Leung DW, Amarasinghe GK. A Sensitive In Vitro High-Throughput Screen to Identify Pan-Filoviral Replication Inhibitors Targeting the VP35-NP Interface. Acs Infectious Diseases. PMID 28152588 DOI: 10.1021/Acsinfecdis.6B00209  0.413
2017 Kuzmin IV, Schwarz TM, Ilinykh PA, Jordan I, Ksiazek TG, Sachidanandam R, Basler CF, Bukreyev A. Innate Immune Response of Bat and Human Cells to Filoviruses: Commonalities and Distinctions. Journal of Virology. PMID 28122983 DOI: 10.1128/Jvi.02471-16  0.489
2017 Ginell GM, Amarasinghe GK, Basler CF, Keefe LJ, Leung DW. Structural studies of ebola viral homolog encoded by microbats Acta Crystallographica Section a Foundations and Advances. 73: a273-a273. DOI: 10.1107/S0108767317097318  0.435
2016 Schwarz TM, Edwards MR, Diederichs A, Alinger JB, Leung DW, Amarasinghe GK, Basler CF. VP24-karyopherin alpha binding affinities differ between Ebolavirus species influencing interferon inhibition and VP24 stability. Journal of Virology. PMID 27974555 DOI: 10.1128/Jvi.01715-16  0.468
2016 Postler TS, Clawson AN, Amarasinghe GK, Basler CF, Bavari S, Benkő M, Blasdell KR, Briese T, Buchmeier MJ, Bukreyev A, Calisher CH, Chandran K, Charrel R, Clegg CS, Collins PL, et al. Possibility and Challenges of Conversion of Current Virus Species Names to Linnaean Binomials. Systematic Biology. PMID 27798405 DOI: 10.1093/Sysbio/Syw096  0.373
2016 Bharaj P, Wang YE, Dawes BE, Yun TE, Park A, Yen B, Basler CF, Freiberg AN, Lee B, Rajsbaum R. The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response. Plos Pathogens. 12: e1005880. PMID 27622505 DOI: 10.1371/Journal.Ppat.1005880  0.54
2016 Johnson B, Li J, Adhikari J, Edwards MR, Zhang H, Schwarz T, Leung DW, Basler CF, Gross ML, Amarasinghe GK. Dimerization controls Marburg virus VP24-dependent modulation of host antioxidative stress responses. Journal of Molecular Biology. PMID 27497688 DOI: 10.1016/J.Jmb.2016.07.020  0.5
2016 Chatterjee S, Basler CF, Amarasinghe GK, Leung DW. Molecular mechanisms of innate immune inhibition by non-segmented negative-sense RNA viruses. Journal of Molecular Biology. PMID 27487481 DOI: 10.1016/J.Jmb.2016.07.017  0.505
2016 Shabman RS, Shrivastava S, Tsibane T, Attie O, Jayaprakash A, Mire CE, Dilley KE, Puri V, Stockwell TB, Geisbert TW, Sachidanandam R, Basler CF. Isolation and Characterization of a Novel Gammaherpesvirus from a Microbat Cell Line. Msphere. 1. PMID 27303702 DOI: 10.1128/mSphere.00070-15  0.378
2016 Satterfield BA, Cross RW, Fenton KA, Borisevich V, Agans KN, Deer DJ, Graber J, Basler CF, Geisbert TW, Mire CE. The Nipah virus C and W proteins contribute to respiratory disease in ferrets. Journal of Virology. PMID 27147733 DOI: 10.1128/Jvi.00215-16  0.37
2016 Rialdi A, Campisi L, Zhao N, Lagda AC, Pietzsch C, Ho JS, Martinez-Gil L, Fenouil R, Chen X, Edwards M, Metreveli G, Jordan S, Peralta Z, Munoz-Fontela C, Bouvier N, ... ... Basler C, et al. Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation. Science (New York, N.Y.). PMID 27127234 DOI: 10.1126/Science.Aad7993  0.405
2016 Yen BC, Basler CF. Effects of Filovirus IFN Antagonists on Responses of Human Monocyte-Derived Dendritic Cells to RNA virus infection. Journal of Virology. PMID 26962215 DOI: 10.1128/Jvi.00191-16  0.549
2016 Edwards MR, Liu G, Mire CE, Sureshchandra S, Luthra P, Yen B, Shabman RS, Leung DW, Messaoudi I, Geisbert TW, Amarasinghe GK, Basler CF. Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins. Cell Reports. PMID 26876165 DOI: 10.1016/J.Celrep.2016.01.049  0.517
2016 Esposito AM, Cheung P, Swartz TH, Li H, Tsibane T, Durham ND, Basler CF, Felsenfeld DP, Chen BK. A high throughput Cre-lox activated viral membrane fusion assay identifies pharmacological inhibitors of HIV entry. Virology. 490: 6-16. PMID 26803470 DOI: 10.1016/J.Virol.2015.10.013  0.382
2015 Messaoudi I, Amarasinghe GK, Basler CF. Filovirus pathogenesis and immune evasion: insights from Ebola virus and Marburg virus. Nature Reviews. Microbiology. 13: 663-76. PMID 26439085 DOI: 10.1038/Nrmicro3524  0.523
2015 Edwards MR, Pietzsch C, Vausselin T, Shaw ML, Bukreyev A, Basler CF. High-Throughput Minigenome System for Identifying Small-Molecule Inhibitors of Ebola Virus Replication. Acs Infectious Diseases. 1: 380-387. PMID 26284260 DOI: 10.1021/Acsinfecdis.5B00053  0.463
2015 Feagins AR, Basler CF. Lloviu virus VP24 and VP35 proteins function as innate immune antagonists in human and bat cells. Virology. 485: 145-52. PMID 26255028 DOI: 10.1016/J.Virol.2015.07.010  0.61
2015 Messaoudi I, Basler CF. Immunological features underlying viral hemorrhagic fevers. Current Opinion in Immunology. 36: 38-46. PMID 26163194 DOI: 10.1016/J.Coi.2015.06.003  0.448
2015 Satterfield BA, Cross RW, Fenton KA, Agans KN, Basler CF, Geisbert TW, Mire CE. The immunomodulating V and W proteins of Nipah virus determine disease course. Nature Communications. 6: 7483. PMID 26105519 DOI: 10.1038/Ncomms8483  0.453
2015 Edwards MR, Basler CF. Marburg Virus VP24 Protein Relieves Suppression of the NF-κB Pathway Through Interaction With Kelch-like ECH-Associated Protein 1. The Journal of Infectious Diseases. 212: S154-9. PMID 25926686 DOI: 10.1093/Infdis/Jiv050  0.415
2015 Feagins AR, Basler CF. Amino Acid Residue at Position 79 of Marburg Virus VP40 Confers Interferon Antagonism in Mouse Cells. The Journal of Infectious Diseases. 212: S219-25. PMID 25926685 DOI: 10.1093/Infdis/Jiv010  0.443
2015 Leung DW, Borek D, Luthra P, Binning JM, Anantpadma M, Liu G, Harvey IB, Su Z, Endlich-Frazier A, Pan J, Shabman RS, Chiu W, Davey RA, Otwinowski Z, Basler CF, et al. An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions. Cell Reports. 11: 376-89. PMID 25865894 DOI: 10.1016/J.Celrep.2015.03.034  0.373
2015 Basler CF. Innate immune evasion by filoviruses. Virology. 479: 122-30. PMID 25843618 DOI: 10.1016/J.Virol.2015.03.030  0.464
2015 Miller MS, Rialdi A, Ho JS, Tilove M, Martinez-Gil L, Moshkina NP, Peralta Z, Noel J, Melegari C, Maestre AM, Mitsopoulos P, Madrenas J, Heinz S, Benner C, Young JA, ... ... Basler CF, et al. Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis. Nature Immunology. 16: 485-94. PMID 25822250 DOI: 10.1038/Ni.3132  0.517
2015 Ciancanelli MJ, Huang SX, Luthra P, Garner H, Itan Y, Volpi S, Lafaille FG, Trouillet C, Schmolke M, Albrecht RA, Israelsson E, Lim HK, Casadio M, Hermesh T, Lorenzo L, ... ... Basler CF, et al. Infectious disease. Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency. Science (New York, N.Y.). 348: 448-53. PMID 25814066 DOI: 10.1126/Science.Aaa1578  0.782
2015 Luthra P, Jordan DS, Leung DW, Amarasinghe GK, Basler CF. Ebola virus VP35 interaction with dynein LC8 regulates viral RNA synthesis. Journal of Virology. 89: 5148-53. PMID 25741013 DOI: 10.1128/Jvi.03652-14  0.526
2015 Teixeira A, Yen B, Gusella GL, Thomas AG, Mullen MP, Aberg J, Chen X, Hoshida Y, van Bakel H, Schadt E, Basler CF, García-Sastre A, Mosoian A. Prothymosin α variants isolated from CD8+ T cells and cervicovaginal fluid suppress HIV-1 replication through type I interferon induction. The Journal of Infectious Diseases. 211: 1467-75. PMID 25404520 DOI: 10.1093/Infdis/Jiu643  0.365
2014 Shabman RS, Jabado OJ, Mire CE, Stockwell TB, Edwards M, Mahajan M, Geisbert TW, Basler CF. Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells. Mbio. 5: e02011. PMID 25370495 DOI: 10.1128/Mbio.02011-14  0.396
2014 Basler CF. New hope in the search for Ebola virus treatments. Immunity. 41: 515-7. PMID 25367568 DOI: 10.1016/J.Immuni.2014.10.001  0.441
2014 Basler CF. Portrait of a killer: genome of the 2014 EBOV outbreak strain. Cell Host & Microbe. 16: 419-21. PMID 25299323 DOI: 10.1016/J.Chom.2014.09.012  0.37
2014 Feagins AR, Basler CF. The VP40 protein of Marburg virus exhibits impaired budding and increased sensitivity to human tetherin following mouse adaptation. Journal of Virology. 88: 14440-50. PMID 25297995 DOI: 10.1128/Jvi.02069-14  0.497
2014 Yen B, Mulder LC, Martinez O, Basler CF. Molecular basis for ebolavirus VP35 suppression of human dendritic cell maturation. Journal of Virology. 88: 12500-10. PMID 25142601 DOI: 10.1128/Jvi.02163-14  0.457
2014 Xu W, Edwards MR, Borek DM, Feagins AR, Mittal A, Alinger JB, Berry KN, Yen B, Hamilton J, Brett TJ, Pappu RV, Leung DW, Basler CF, Amarasinghe GK. Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1. Cell Host & Microbe. 16: 187-200. PMID 25121748 DOI: 10.1016/J.Chom.2014.07.008  0.465
2014 Johnson JC, Martinez O, Honko AN, Hensley LE, Olinger GG, Basler CF. Pyridinyl imidazole inhibitors of p38 MAP kinase impair viral entry and reduce cytokine induction by Zaire ebolavirus in human dendritic cells. Antiviral Research. 107: 102-9. PMID 24815087 DOI: 10.1016/J.Antiviral.2014.04.014  0.457
2014 Basler CF, Woo PC. Editorial overview: emerging viruses. Current Opinion in Virology. 5: v-vii. PMID 24680706 DOI: 10.1016/J.Coviro.2014.03.002  0.413
2014 Edwards MR, Johnson B, Mire CE, Xu W, Shabman RS, Speller LN, Leung DW, Geisbert TW, Amarasinghe GK, Basler CF. The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway. Cell Reports. 6: 1017-25. PMID 24630991 DOI: 10.1016/J.Celrep.2014.01.043  0.463
2014 Brown CS, Lee MS, Leung DW, Wang T, Xu W, Luthra P, Anantpadma M, Shabman RS, Melito LM, MacMillan KS, Borek DM, Otwinowski Z, Ramanan P, Stubbs AJ, Peterson DS, ... ... Basler CF, et al. In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity. Journal of Molecular Biology. 426: 2045-58. PMID 24495995 DOI: 10.1016/J.Jmb.2014.01.010  0.521
2013 Binning JM, Wang T, Luthra P, Shabman RS, Borek DM, Liu G, Xu W, Leung DW, Basler CF, Amarasinghe GK. Development of RNA aptamers targeting Ebola virus VP35 Biochemistry. 52: 8406-8419. PMID 24067086 DOI: 10.1021/Bi400704D  0.512
2013 Miller MS, Gardner TJ, Krammer F, Aguado LC, Tortorella D, Basler CF, Palese P. Neutralizing antibodies against previously encountered influenza virus strains increase over time: a longitudinal analysis. Science Translational Medicine. 5: 198ra107. PMID 23946196 DOI: 10.1126/Scitranslmed.3006637  0.423
2013 Luthra P, Ramanan P, Mire CE, Weisend C, Tsuda Y, Yen B, Liu G, Leung DW, Geisbert TW, Ebihara H, Amarasinghe GK, Basler CF. Mutual antagonism between the ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome Cell Host and Microbe. 14: 74-84. PMID 23870315 DOI: 10.1016/J.Chom.2013.06.010  0.58
2013 Basler CF. A novel mechanism of immune evasion mediated by Ebola virus soluble glycoprotein. Expert Review of Anti-Infective Therapy. 11: 475-8. PMID 23627853 DOI: 10.1586/Eri.13.30  0.439
2013 Shabman RS, Hoenen T, Groseth A, Jabado O, Binning JM, Amarasinghe GK, Feldmann H, Basler CF. An upstream open reading frame modulates ebola virus polymerase translation and virus replication. Plos Pathogens. 9: e1003147. PMID 23382680 DOI: 10.1371/Journal.Ppat.1003147  0.479
2013 Martinez O, Johnson JC, Honko A, Yen B, Shabman RS, Hensley LE, Olinger GG, Basler CF. Ebola virus exploits a monocyte differentiation program to promote its entry. Journal of Virology. 87: 3801-14. PMID 23345511 DOI: 10.1128/Jvi.02695-12  0.439
2013 Martinez O, Ndungo E, Tantral L, Miller EH, Leung LW, Chandran K, Basler CF. A mutation in the Ebola virus envelope glycoprotein restricts viral entry in a host species- and cell-type-specific manner. Journal of Virology. 87: 3324-34. PMID 23302883 DOI: 10.1128/Jvi.01598-12  0.446
2013 Miller MS, Tsibane T, Krammer F, Hai R, Rahmat S, Basler CF, Palese P. 1976 and 2009 H1N1 influenza virus vaccines boost anti-hemagglutinin stalk antibodies in humans. The Journal of Infectious Diseases. 207: 98-105. PMID 23087428 DOI: 10.1093/Infdis/Jis652  0.312
2012 Tsibane T, Ekiert DC, Krause JC, Martinez O, Crowe JE, Wilson IA, Basler CF. Influenza human monoclonal antibody 1F1 interacts with three major antigenic sites and residues mediating human receptor specificity in H1N1 viruses. Plos Pathogens. 8: e1003067. PMID 23236279 DOI: 10.1371/Journal.Ppat.1003067  0.34
2012 Ramanan P, Edwards MR, Shabman RS, Leung DW, Endlich-Frazier AC, Borek DM, Otwinowski Z, Liu G, Huh J, Basler CF, Amarasinghe GK. Structural basis for Marburg virus VP35-mediated immune evasion mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 109: 20661-20666. PMID 23185024 DOI: 10.1073/Pnas.1213559109  0.56
2012 Weisfuse IB, Tsibane T, Konty KJ, Egger JR, Waddell EN, Rahmat S, Harris E, Olson DR, Basler CF. Seroprevalence of pandemic influenza viruses, New York, New York, USA, 2004. Emerging Infectious Diseases. 18: 1905-7. PMID 23092519 DOI: 10.3201/Eid1811.120156  0.451
2012 Hoenen T, Shabman RS, Groseth A, Herwig A, Weber M, Schudt G, Dolnik O, Basler CF, Becker S, Feldmann H. Inclusion bodies are a site of ebolavirus replication. Journal of Virology. 86: 11779-88. PMID 22915810 DOI: 10.1128/Jvi.01525-12  0.426
2012 Basler CF. Nipah and hendra virus interactions with the innate immune system. Current Topics in Microbiology and Immunology. 359: 123-52. PMID 22491899 DOI: 10.1007/82_2012_209  0.562
2012 Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Albrecht R, Blum DL, Ramos I, Fernandez-Sesma A, Edwards KM, García-Sastre A, Basler CF, Crowe JE. Human monoclonal antibodies to pandemic 1957 H2N2 and pandemic 1968 H3N2 influenza viruses. Journal of Virology. 86: 6334-40. PMID 22457520 DOI: 10.1128/Jvi.07158-11  0.448
2012 Martinez O, Leung LW, Basler CF. The role of antigen-presenting cells in filoviral hemorrhagic fever: gaps in current knowledge. Antiviral Research. 93: 416-28. PMID 22333482 DOI: 10.1016/J.Antiviral.2012.01.011  0.485
2012 Leung DW, Basler CF, Amarasinghe GK. Molecular mechanisms of viral inhibitors of RIG-I-like receptors Trends in Microbiology. 20: 139-146. PMID 22325030 DOI: 10.1016/J.Tim.2011.12.005  0.471
2012 Yu X, Tsibane T, McGraw PA, House FS, Keefer CJ, Hicar MD, Tumpey TM, Pappas C, Perrone LA, Martinez O, Stevens J, Wilson IA, Aguilar PV, Altschuler EL, Basler CF, et al. Erratum: Corrigendum: Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors Nature. 490: 570-570. DOI: 10.1038/Nature11235  0.36
2011 Ramanan P, Shabman RS, Brown CS, Amarasinghe GK, Basler CF, Leung DW. Filoviral immune evasion mechanisms Viruses. 3: 1634-1649. PMID 21994800 DOI: 10.3390/V3091634  0.488
2011 Leung LW, Martinez O, Reynard O, Volchkov VE, Basler CF. Ebola virus failure to stimulate plasmacytoid dendritic cell interferon responses correlates with impaired cellular entry. The Journal of Infectious Diseases. 204: S973-7. PMID 21987778 DOI: 10.1093/Infdis/Jir331  0.526
2011 Shabman RS, Leung DW, Johnson J, Glennon N, Gulcicek EE, Stone KL, Leung L, Hensley L, Amarasinghe GK, Basler CF. DRBP76 associates with Ebola virus VP35 and suppresses viral polymerase function. The Journal of Infectious Diseases. 204: S911-8. PMID 21987769 DOI: 10.1093/Infdis/Jir343  0.583
2011 Shabman RS, Gulcicek EE, Stone KL, Basler CF. The Ebola virus VP24 protein prevents hnRNP C1/C2 binding to karyopherin α1 and partially alters its nuclear import. The Journal of Infectious Diseases. 204: S904-10. PMID 21987768 DOI: 10.1093/Infdis/Jir323  0.366
2011 Reynard O, Reid SP, Page A, Mateo M, Alazard-Dany N, Raoul H, Basler CF, Volchkov VE. Unconventional secretion of Ebola virus matrix protein VP40. The Journal of Infectious Diseases. 204: S833-9. PMID 21987759 DOI: 10.1093/Infdis/Jir305  0.757
2011 Martinez O, Tantral L, Mulherkar N, Chandran K, Basler CF. Impact of Ebola mucin-like domain on antiglycoprotein antibody responses induced by Ebola virus-like particles. The Journal of Infectious Diseases. 204: S825-32. PMID 21987758 DOI: 10.1093/Infdis/Jir295  0.428
2011 Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Briney BS, Smith SA, Basler CF, Crowe JE. Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence. Journal of Immunology (Baltimore, Md. : 1950). 187: 3704-11. PMID 21880983 DOI: 10.4049/Jimmunol.1101823  0.401
2011 Krause JC, Tsibane T, Tumpey TM, Huffman CJ, Basler CF, Crowe JE. A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin. Journal of Virology. 85: 10905-8. PMID 21849447 DOI: 10.1128/Jvi.00700-11  0.444
2011 Walpita P, Barr J, Sherman M, Basler CF, Wang L. Vaccine potential of Nipah virus-like particles. Plos One. 6: e18437. PMID 21494680 DOI: 10.1371/Journal.Pone.0018437  0.453
2011 Valmas C, Basler CF. Marburg virus VP40 antagonizes interferon signaling in a species-specific manner. Journal of Virology. 85: 4309-17. PMID 21325424 DOI: 10.1128/Jvi.02575-10  0.817
2011 Leung LW, Park MS, Martinez O, Valmas C, López CB, Basler CF. Ebolavirus VP35 suppresses IFN production from conventional but not plasmacytoid dendritic cells. Immunology and Cell Biology. 89: 792-802. PMID 21263462 DOI: 10.1038/Icb.2010.169  0.815
2010 Leung DW, Prins KC, Basler CF, Amarasinghe GK. Ebolavirus VP35 is a multifunctional virulence factor Virulence. 1: 526-531. PMID 21178490 DOI: 10.4161/Viru.1.6.12984  0.825
2010 Medina RA, Manicassamy B, Stertz S, Seibert CW, Hai R, Belshe RB, Frey SE, Basler CF, Palese P, García-Sastre A. Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus. Nature Communications. 1: 28. PMID 20975689 DOI: 10.1038/Ncomms1026  0.426
2010 Fytas C, Kolocouris A, Fytas G, Zoidis G, Valmas C, Basler CF. Influence of an additional amino group on the potency of aminoadamantanes against influenza virus A. II - Synthesis of spiropiperazines and in vitro activity against influenza A H3N2 virus. Bioorganic Chemistry. 38: 247-51. PMID 20926112 DOI: 10.1016/J.Bioorg.2010.09.001  0.8
2010 Prins KC, Binning JM, Shabman RS, Leung DW, Amarasinghe GK, Basler CF. Basic residues within the ebolavirus VP35 protein are required for its viral polymerase cofactor function Journal of Virology. 84: 10581-10591. PMID 20686031 DOI: 10.1128/Jvi.00925-10  0.815
2010 Leung DW, Borek D, Farahbakhsh M, Ramanan P, Nix JC, Wang T, Prins KC, Otwinowski Z, Honzatko RB, Helgeson LA, Basler CF, Amarasinghe GK. Crystallization and preliminary X-ray analysis of Ebola VP35 interferon inhibitory domain mutant proteins Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 66: 689-692. PMID 20516601 DOI: 10.1107/S1744309110013266  0.803
2010 Leung DW, Shabman RS, Farahbakhsh M, Prins KC, Borek DM, Wang T, Mühlberger E, Basler CF, Amarasinghe GK. Structural and functional characterization of Reston Ebola virus VP35 interferon inhibitory domain Journal of Molecular Biology. 399: 347-357. PMID 20399790 DOI: 10.1016/J.Jmb.2010.04.022  0.837
2010 Manicassamy B, Medina RA, Hai R, Tsibane T, Stertz S, Nistal-Villán E, Palese P, Basler CF, García-Sastre A. Protection of mice against lethal challenge with 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 based vaccines. Plos Pathogens. 6: e1000745. PMID 20126449 DOI: 10.1371/Journal.Ppat.1000745  0.453
2010 Valmas C, Grosch MN, Schümann M, Olejnik J, Martinez O, Best SM, Krähling V, Basler CF, Mühlberger E. Marburg virus evades interferon responses by a mechanism distinct from ebola virus. Plos Pathogens. 6: e1000721. PMID 20084112 DOI: 10.1371/Journal.Ppat.1000721  0.807
2010 Leung DW, Prins KC, Borek DM, Farahbakhsh M, Tufariello JM, Ramanan P, Nix JC, Helgeson LA, Otwinowski Z, Honzatko RB, Basler CF, Amarasinghe GK. Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35 Nature Structural and Molecular Biology. 17: 165-172. PMID 20081868 DOI: 10.1038/Nsmb.1765  0.826
2010 Prins KC, Delpeut S, Leung DW, Reynard O, Volchkova VA, Reid SP, Ramanan P, Cárdenas WB, Amarasinghe GK, Volchkov VE, Basler CF. Mutations abrogating VP35 interaction with double-stranded RNA render Ebola virus avirulent in guinea pigs Journal of Virology. 84: 3004-3015. PMID 20071589 DOI: 10.1128/Jvi.02459-09  0.829
2010 Krause JC, Tumpey TM, Huffman CJ, McGraw PA, Pearce MB, Tsibane T, Hai R, Basler CF, Crowe JE. Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses. Journal of Virology. 84: 3127-30. PMID 20042511 DOI: 10.1128/Jvi.02184-09  0.456
2010 Xu R, McBride R, Paulson JC, Basler CF, Wilson IA. Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic. Journal of Virology. 84: 1715-21. PMID 20007271 DOI: 10.1128/Jvi.02162-09  0.447
2010 Martínez-Sobrido L, Cadagan R, Steel J, Basler CF, Palese P, Moran TM, García-Sastre A. Hemagglutinin-pseudotyped green fluorescent protein-expressing influenza viruses for the detection of influenza virus neutralizing antibodies. Journal of Virology. 84: 2157-63. PMID 19939917 DOI: 10.1128/Jvi.01433-09  0.463
2010 Mateo M, Reid SP, Leung LW, Basler CF, Volchkov VE. Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling. Journal of Virology. 84: 1169-75. PMID 19889762 DOI: 10.1128/Jvi.01372-09  0.725
2010 Martinez O, Johnson J, Manicassamy B, Rong L, Olinger GG, Hensley LE, Basler CF. Zaire Ebola virus entry into human dendritic cells is insensitive to cathepsin L inhibition. Cellular Microbiology. 12: 148-57. PMID 19775255 DOI: 10.1111/J.1462-5822.2009.01385.X  0.395
2009 Basler CF, Amarasinghe GK. Evasion of interferon responses by Ebola and Marburg viruses. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 29: 511-20. PMID 19694547 DOI: 10.1089/Jir.2009.0076  0.62
2009 Ciancanelli MJ, Volchkova VA, Shaw ML, Volchkov VE, Basler CF. Nipah virus sequesters inactive STAT1 in the nucleus via a P gene-encoded mechanism. Journal of Virology. 83: 7828-41. PMID 19515782 DOI: 10.1128/Jvi.02610-08  0.785
2009 Martinez O, Tsibane T, Basler CF. Neutralizing anti-influenza virus monoclonal antibodies: therapeutics and tools for discovery. International Reviews of Immunology. 28: 69-92. PMID 19241254 DOI: 10.1080/08830180802593540  0.415
2009 Kulkarni S, Volchkova V, Basler CF, Palese P, Volchkov VE, Shaw ML. Nipah virus edits its P gene at high frequency to express the V and W proteins. Journal of Virology. 83: 3982-7. PMID 19211754 DOI: 10.1128/Jvi.02599-08  0.365
2009 Leung DW, Ginder ND, Nix JC, Basler CF, Honzatko RB, Amarasinghe GK. Expression, purification, crystallization and preliminary X-ray studies of the Ebola VP35 interferon inhibitory domain Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 65: 163-165. PMID 19194011 DOI: 10.1107/S1744309108044187  0.364
2009 Prins KC, Cárdenas WB, Basler CF. Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1. Journal of Virology. 83: 3069-77. PMID 19153231 DOI: 10.1128/Jvi.01875-08  0.814
2009 Leung DW, Ginder ND, Fulton DB, Nix J, Basler CF, Honzatko RB, Amarasinghe GK. Structure of the Ebola VP35 interferon inhibitory domain Proceedings of the National Academy of Sciences of the United States of America. 106: 411-416. PMID 19122151 DOI: 10.1073/Pnas.0807854106  0.522
2008 Aiki-Raji CO, Aguilar PV, Kwon YK, Goetz S, Suarez DL, Jethra AI, Nash O, Adeyefa CA, Adu FD, Swayne D, Basler CF. Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria. Emerging Infectious Diseases. 14: 1753-5. PMID 18976562 DOI: 10.3201/Eid1411.080557  0.393
2008 Yu X, Tsibane T, McGraw PA, House FS, Keefer CJ, Hicar MD, Tumpey TM, Pappas C, Perrone LA, Martinez O, Stevens J, Wilson IA, Aguilar PV, Altschuler EL, Basler CF, et al. Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors. Nature. 455: 532-6. PMID 18716625 DOI: 10.1038/Nature07231  0.469
2008 Friedman CS, O'Donnell MA, Legarda-Addison D, Ng A, Cárdenas WB, Yount JS, Moran TM, Basler CF, Komuro A, Horvath CM, Xavier R, Ting AT. The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response. Embo Reports. 9: 930-6. PMID 18636086 DOI: 10.1038/Embor.2008.136  0.458
2008 Basler CF, Aguilar PV. Progress in identifying virulence determinants of the 1918 H1N1 and the Southeast Asian H5N1 influenza A viruses. Antiviral Research. 79: 166-78. PMID 18547656 DOI: 10.1016/J.Antiviral.2008.04.006  0.506
2008 Aguilar PV, Leung LW, Wang E, Weaver SC, Basler CF. A five-amino-acid deletion of the eastern equine encephalitis virus capsid protein attenuates replication in mammalian systems but not in mosquito cells. Journal of Virology. 82: 6972-83. PMID 18480443 DOI: 10.1128/Jvi.01283-07  0.493
2008 Pappas C, Aguilar PV, Basler CF, Solórzano A, Zeng H, Perrone LA, Palese P, García-Sastre A, Katz JM, Tumpey TM. Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus. Proceedings of the National Academy of Sciences of the United States of America. 105: 3064-9. PMID 18287069 DOI: 10.1073/Pnas.0711815105  0.487
2008 Reid SP, Valmas C, Martinez O, Sanchez FM, Basler CF. Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin α proteins with activated STAT1 (Journal of Virology (2007) 81, 24, (13469-13477)) Journal of Virology. 82. DOI: 10.1128/Jvi.00069-08  0.813
2007 Basler CF. Influenza viruses: basic biology and potential drug targets. Infectious Disorders Drug Targets. 7: 282-93. PMID 18220960 DOI: 10.2174/187152607783018745  0.435
2007 Reid SP, Valmas C, Martinez O, Sanchez FM, Basler CF. Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1. Journal of Virology. 81: 13469-77. PMID 17928350 DOI: 10.1128/Jvi.01097-07  0.779
2007 Martinez O, Valmas C, Basler CF. Ebola virus-like particle-induced activation of NF-kappaB and Erk signaling in human dendritic cells requires the glycoprotein mucin domain. Virology. 364: 342-54. PMID 17434557 DOI: 10.1016/J.Virol.2007.03.020  0.812
2007 Aguilar PV, Weaver SC, Basler CF. Capsid protein of eastern equine encephalitis virus inhibits host cell gene expression. Journal of Virology. 81: 3866-76. PMID 17267491 DOI: 10.1128/Jvi.02075-06  0.484
2007 Basler CF, García-Sastre A. Sensing RNA virus infections. Nature Chemical Biology. 3: 20-1. PMID 17173024 DOI: 10.1038/Nchembio0107-20  0.385
2007 Basler C. Editorial [Hot Topic: Influenza Virus Pathogenesis and Drug Targets (Guest Editor: Christopher F. Basler)] Infectious Disorders - Drug Targets. 7: 281-281. DOI: 10.2174/187152607783018781  0.379
2006 Kash JC, Tumpey TM, Proll SC, Carter V, Perwitasari O, Thomas MJ, Basler CF, Palese P, Taubenberger JK, García-Sastre A, Swayne DE, Katze MG. Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus. Nature. 443: 578-81. PMID 17006449 DOI: 10.1038/Nature05181  0.509
2006 Ciancanelli MJ, Basler CF. Mutation of YMYL in the Nipah virus matrix protein abrogates budding and alters subcellular localization. Journal of Virology. 80: 12070-8. PMID 17005661 DOI: 10.1128/Jvi.01743-06  0.757
2006 Cárdenas WB, Loo YM, Gale M, Hartman AL, Kimberlin CR, Martínez-Sobrido L, Saphire EO, Basler CF. Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling. Journal of Virology. 80: 5168-78. PMID 16698997 DOI: 10.1128/Jvi.02199-05  0.548
2006 Reid SP, Leung LW, Hartman AL, Martinez O, Shaw ML, Carbonnelle C, Volchkov VE, Nichol ST, Basler CF. Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation. Journal of Virology. 80: 5156-67. PMID 16698996 DOI: 10.1128/Jvi.02349-05  0.731
2005 Tumpey TM, García-Sastre A, Taubenberger JK, Palese P, Swayne DE, Pantin-Jackwood MJ, Schultz-Cherry S, Solórzano A, Van Rooijen N, Katz JM, Basler CF. Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice. Journal of Virology. 79: 14933-44. PMID 16282492 DOI: 10.1128/Jvi.79.23.14933-14944.2005  0.476
2005 Tumpey TM, Basler CF, Aguilar PV, Zeng H, Solórzano A, Swayne DE, Cox NJ, Katz JM, Taubenberger JK, Palese P, García-Sastre A. Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science (New York, N.Y.). 310: 77-80. PMID 16210530 DOI: 10.1126/Science.1119392  0.489
2005 Glaser L, Stevens J, Zamarin D, Wilson IA, García-Sastre A, Tumpey TM, Basler CF, Taubenberger JK, Palese P. A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity. Journal of Virology. 79: 11533-6. PMID 16103207 DOI: 10.1128/Jvi.79.17.11533-11536.2005  0.404
2005 Reid SP, Cárdenas WB, Basler CF. Homo-oligomerization facilitates the interferon-antagonist activity of the ebolavirus VP35 protein. Virology. 341: 179-89. PMID 16095644 DOI: 10.1016/J.Virol.2005.06.044  0.745
2005 Shaw ML, Cardenas WB, Zamarin D, Palese P, Basler CF. Nuclear localization of the Nipah virus W protein allows for inhibition of both virus- and toll-like receptor 3-triggered signaling pathways. Journal of Virology. 79: 6078-88. PMID 15857993 DOI: 10.1128/Jvi.79.10.6078-6088.2005  0.531
2004 Donelan NR, Dauber B, Wang X, Basler CF, Wolff T, García-Sastre A. The N- and C-terminal domains of the NS1 protein of influenza B virus can independently inhibit IRF-3 and beta interferon promoter activation. Journal of Virology. 78: 11574-82. PMID 15479798 DOI: 10.1128/Jvi.78.21.11574-11582.2004  0.55
2004 Kash JC, Basler CF, García-Sastre A, Carter V, Billharz R, Swayne DE, Przygodzki RM, Taubenberger JK, Katze MG, Tumpey TM. Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus. Journal of Virology. 78: 9499-511. PMID 15308742 DOI: 10.1128/Jvi.78.17.9499-9511.2004  0.48
2004 Shaw ML, García-Sastre A, Palese P, Basler CF. Nipah virus V and W proteins have a common STAT1-binding domain yet inhibit STAT1 activation from the cytoplasmic and nuclear compartments, respectively. Journal of Virology. 78: 5633-41. PMID 15140960 DOI: 10.1128/Jvi.78.11.5633-5641.2004  0.516
2004 Tumpey TM, García-Sastre A, Taubenberger JK, Palese P, Swayne DE, Basler CF. Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus. Proceedings of the National Academy of Sciences of the United States of America. 101: 3166-71. PMID 14963236 DOI: 10.1073/Pnas.0308391100  0.46
2004 Stevens J, Corper AL, Basler CF, Taubenberger JK, Palese P, Wilson IA. Structure of the uncleaved human H1 hemagglutinin from the extinct 1918 influenza virus. Science (New York, N.Y.). 303: 1866-70. PMID 14764887 DOI: 10.1126/Science.1093373  0.478
2003 Donelan NR, Basler CF, García-Sastre A. A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice. Journal of Virology. 77: 13257-66. PMID 14645582 DOI: 10.1128/Jvi.77.24.13257-13266.2003  0.577
2003 Park MS, García-Sastre A, Cros JF, Basler CF, Palese P. Newcastle disease virus V protein is a determinant of host range restriction. Journal of Virology. 77: 9522-32. PMID 12915566 DOI: 10.1128/Jvi.77.17.9522-9532.2003  0.492
2003 Flandorfer A, García-Sastre A, Basler CF, Palese P. Chimeric influenza A viruses with a functional influenza B virus neuraminidase or hemagglutinin. Journal of Virology. 77: 9116-23. PMID 12915528 DOI: 10.1128/Jvi.77.17.9116-9123.2003  0.477
2003 Basler CF, Mikulasova A, Martinez-Sobrido L, Paragas J, Mühlberger E, Bray M, Klenk HD, Palese P, García-Sastre A. The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3. Journal of Virology. 77: 7945-56. PMID 12829834 DOI: 10.1128/Jvi.77.14.7945-7956.2003  0.594
2003 Park MS, Shaw ML, Muñoz-Jordan J, Cros JF, Nakaya T, Bouvier N, Palese P, García-Sastre A, Basler CF. Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins. Journal of Virology. 77: 1501-11. PMID 12502864 DOI: 10.1128/Jvi.77.2.1501-1511.2003  0.576
2002 Basler CF, García-Sastre A. Viruses and the type I interferon antiviral system: induction and evasion. International Reviews of Immunology. 21: 305-37. PMID 12486817 DOI: 10.1080/08830180213277  0.531
2002 Wang X, Basler CF, Williams BR, Silverman RH, Palese P, García-Sastre A. Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains. Journal of Virology. 76: 12951-62. PMID 12438621 DOI: 10.1128/Jvi.76.24.12951-12962.2002  0.546
2002 Tumpey TM, García-Sastre A, Mikulasova A, Taubenberger JK, Swayne DE, Palese P, Basler CF. Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus. Proceedings of the National Academy of Sciences of the United States of America. 99: 13849-54. PMID 12368467 DOI: 10.1073/Pnas.212519699  0.478
2002 Geiss GK, Salvatore M, Tumpey TM, Carter VS, Wang X, Basler CF, Taubenberger JK, Bumgarner RE, Palese P, Katze MG, García-Sastre A. Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza. Proceedings of the National Academy of Sciences of the United States of America. 99: 10736-41. PMID 12149435 DOI: 10.1073/Pnas.112338099  0.545
2002 Salvatore M, Basler CF, Parisien JP, Horvath CM, Bourmakina S, Zheng H, Muster T, Palese P, García-Sastre A. Effects of influenza A virus NS1 protein on protein expression: the NS1 protein enhances translation and is not required for shutoff of host protein synthesis. Journal of Virology. 76: 1206-12. PMID 11773396 DOI: 10.1128/Jvi.76.3.1206-1212.2002  0.542
2001 Basler CF, Reid AH, Dybing JK, Janczewski TA, Fanning TG, Zheng H, Salvatore M, Perdue ML, Swayne DE, García-Sastre A, Palese P, Taubenberger JK. Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes. Proceedings of the National Academy of Sciences of the United States of America. 98: 2746-51. PMID 11226311 DOI: 10.1073/Pnas.031575198  0.508
2001 Momose F, Basler CF, O'Neill RE, Iwamatsu A, Palese P, Nagata K. Cellular splicing factor RAF-2p48/NPI-5/BAT1/UAP56 interacts with the influenza virus nucleoprotein and enhances viral RNA synthesis. Journal of Virology. 75: 1899-908. PMID 11160689 DOI: 10.1128/Jvi.75.4.1899-1908.2001  0.426
2000 Basler CF, Wang X, Mühlberger E, Volchkov V, Paragas J, Klenk HD, García-Sastre A, Palese P. The Ebola virus VP35 protein functions as a type I IFN antagonist. Proceedings of the National Academy of Sciences of the United States of America. 97: 12289-94. PMID 11027311 DOI: 10.1073/Pnas.220398297  0.58
2000 Talon J, Horvath CM, Polley R, Basler CF, Muster T, Palese P, García-Sastre A. Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein. Journal of Virology. 74: 7989-96. PMID 10933707 DOI: 10.1128/Jvi.74.17.7989-7996.2000  0.597
1999 Basler CF, García-Sastre A, Palese P. Mutation of neuraminidase cysteine residues yields temperature-sensitive influenza viruses Journal of Virology. 73: 8095-8103. PMID 10482558 DOI: 10.1128/Jvi.73.10.8095-8103.1999  0.492
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