| Year |
Citation |
Score |
| 2024 |
Kawahata I, Takeda A, Fukunaga K. [Development of early prediction and discriminating techniques for Lewy body diseases]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 159: 2-5. PMID 38171833 DOI: 10.1254/fpj.23065 |
0.362 |
|
| 2023 |
Kawahata I, Sekimori T, Oizumi H, Takeda A, Fukunaga K. Using Fatty Acid-Binding Proteins as Potential Biomarkers to Discriminate between Parkinson's Disease and Dementia with Lewy Bodies: Exploration of a Novel Technique. International Journal of Molecular Sciences. 24. PMID 37686075 DOI: 10.3390/ijms241713267 |
0.315 |
|
| 2022 |
Oizumi H, Sugimura Y, Totsune T, Kawasaki I, Ohshiro S, Baba T, Kimpara T, Sakuma H, Hasegawa T, Kawahata I, Fukunaga K, Takeda A. Plasma sphingolipid abnormalities in neurodegenerative diseases. Plos One. 17: e0279315. PMID 36525454 DOI: 10.1371/journal.pone.0279315 |
0.311 |
|
| 2020 |
Kanno S, Shinohara M, Kanno K, Gomi Y, Uchiyama M, Nishio Y, Baba T, Hosokai Y, Takeda A, Fukuda H, Mori E, Suzuki K. Neural substrates underlying progressive micrographia in Parkinson's disease. Brain and Behavior. e01669. PMID 32558361 DOI: 10.1002/Brb3.1669 |
0.356 |
|
| 2020 |
Gang M, Baba T, Hosokai Y, Nishio Y, Kikuchi A, Hirayama K, Hasegawa T, Aoki M, Takeda A, Mori E, Suzuki K. Clinical and Cerebral Metabolic Changes in Parkinson's Disease With Basal Forebrain Atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 31971293 DOI: 10.1002/Mds.27988 |
0.34 |
|
| 2020 |
Baba T, Takeda A. Cognitive impairment and its association with cholinergic dysfunction in Parkinson’s disease Neurology and Clinical Neuroscience. DOI: 10.1111/Ncn3.12417 |
0.319 |
|
| 2019 |
Kobayashi J, Hasegawa T, Sugeno N, Yoshida S, Akiyama T, Fujimori K, Hatakeyama H, Miki Y, Tomiyama A, Kawata Y, Fukuda M, Kawahata I, Yamakuni T, Ezura M, Kikuchi A, ... ... Takeda A, et al. Extracellular α-synuclein enters dopaminergic cells by modulating flotillin-1-assisted dopamine transporter endocytosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802051R. PMID 31211923 DOI: 10.1096/Fj.201802051R |
0.31 |
|
| 2019 |
Ezura M, Kikuchi A, Ishiki A, Okamura N, Hasegawa T, Harada R, Watanuki S, Funaki Y, Hiraoka K, Baba T, Sugeno N, Oshima R, Yoshida S, Kobayashi J, Kobayashi M, ... ... Takeda A, et al. Longitudinal changes in F-THK5351 PET in corticobasal syndrome. European Journal of Neurology. PMID 30980575 DOI: 10.1111/Ene.13966 |
0.315 |
|
| 2018 |
Nomoto M, Nagai M, Nishikawa N, Ando R, Kagamiishi Y, Yano K, Saito S, Takeda A. Pharmacokinetics and safety/efficacy of levodopa pro-drug ONO-2160/carbidopa for Parkinson's disease. Eneurologicalsci. 13: 8-13. PMID 30294682 DOI: 10.1016/J.Ensci.2018.09.003 |
0.356 |
|
| 2018 |
Hattori N, Takeda A, Takeda S, Nishimura A, Kitagawa T, Mochizuki H, Nagai M, Takahashi R. Rasagiline monotherapy in early Parkinson's disease: A phase 3, randomized study in Japan. Parkinsonism & Related Disorders. PMID 30205936 DOI: 10.1016/J.Parkreldis.2018.08.024 |
0.327 |
|
| 2018 |
Nishio Y, Yokoi K, Hirayama K, Ishioka T, Hosokai Y, Gang M, Uchiyama M, Baba T, Suzuki K, Takeda A, Mori E. Defining visual illusions in Parkinson's disease: Kinetopsia and object misidentification illusions. Parkinsonism & Related Disorders. PMID 29891431 DOI: 10.1016/J.Parkreldis.2018.05.023 |
0.349 |
|
| 2018 |
Hattori N, Takeda A, Takeda S, Nishimura A, Kato M, Mochizuki H, Nagai M, Takahashi R. Efficacy and safety of adjunctive rasagiline in Japanese Parkinson's disease patients with wearing-off phenomena: A phase 2/3, randomized, double-blind, placebo-controlled, multicenter study. Parkinsonism & Related Disorders. PMID 29748109 DOI: 10.1016/J.Parkreldis.2018.04.025 |
0.311 |
|
| 2018 |
Yoshida S, Hasegawa T, Suzuki M, Sugeno N, Kobayashi J, Ueyama M, Fukuda M, Ido-Fujibayashi A, Sekiguchi K, Ezura M, Kikuchi A, Baba T, Takeda A, Mochizuki H, Nagai Y, et al. Parkinson's disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through perturbation of endosomal trafficking. Human Molecular Genetics. PMID 29309590 DOI: 10.1093/Hmg/Ddy003 |
0.347 |
|
| 2017 |
Nishio Y, Yokoi K, Uchiyama M, Mamiya Y, Watanabe H, Gang M, Baba T, Takeda A, Hirayama K, Mori E. Deconstructing psychosis and misperception symptoms in Parkinson's disease. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 28600444 DOI: 10.1136/Jnnp-2017-315741 |
0.31 |
|
| 2017 |
Baba T, Hosokai Y, Nishio Y, Kikuchi A, Hirayama K, Suzuki K, Hasegawa T, Aoki M, Takeda A, Mori E. Longitudinal study of cognitive and cerebral metabolic changes in Parkinson's disease. Journal of the Neurological Sciences. 372: 288-293. PMID 28017230 DOI: 10.1016/J.Jns.2016.11.068 |
0.347 |
|
| 2017 |
Hasegawa T, Yoshida S, Suzuki M, Sugeno N, Kobayashi J, Ezura M, Kikuchi A, Takeda A, Mochizuki H, Nagai Y, Aoki M. Parkinson’s disease-linked DNAJC13 mutation aggravates alpha-synuclein-induced neurotoxicity through alteration of endosomal trafficking Journal of the Neurological Sciences. 381: 229. DOI: 10.1016/J.Jns.2017.08.656 |
0.331 |
|
| 2017 |
Baba T, Kawasaki I, Mori E, Takeda A. Mechanisms underlying loss of awareness of hyposmia in Parkinson's disease Journal of the Neurological Sciences. 381: 216-217. DOI: 10.1016/J.Jns.2017.08.619 |
0.401 |
|
| 2016 |
Oshima R, Hasegawa T, Tamai K, Sugeno N, Yoshida S, Kobayashi J, Kikuchi A, Baba T, Futatsugi A, Sato I, Satoh K, Takeda A, Aoki M, Tanaka N. ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathways. Scientific Reports. 6: 24997. PMID 27112194 DOI: 10.1038/Srep24997 |
0.371 |
|
| 2016 |
Yoshihara A, Fukatsu M, Hoshi K, Ito H, Nollet K, Yamaguchi Y, Ishii R, Tokuda T, Miyajima M, Arai H, Kato T, Furukawa K, Arai H, Kikuchi A, Takeda A, et al. Subgroup differences in "brain-type" transferrin and α-synuclein in Parkinson's disease and multiple system atrophy. Journal of Biochemistry. PMID 26970280 DOI: 10.1093/Jb/Mvw015 |
0.325 |
|
| 2015 |
Uchiyama M, Nishio Y, Yokoi K, Hosokai Y, Takeda A, Mori E. Pareidolia in Parkinson's disease without dementia: A positron emission tomography study. Parkinsonism & Related Disorders. 21: 603-9. PMID 25864093 DOI: 10.1016/J.Parkreldis.2015.03.020 |
0.312 |
|
| 2014 |
Shoji Y, Nishio Y, Baba T, Uchiyama M, Yokoi K, Ishioka T, Hosokai Y, Hirayama K, Fukuda H, Aoki M, Hasegawa T, Takeda A, Mori E. Neural substrates of cognitive subtypes in Parkinson's disease: a 3-year longitudinal study. Plos One. 9: e110547. PMID 25330390 DOI: 10.1371/Journal.Pone.0110547 |
0.311 |
|
| 2014 |
Kashihara K, Kondo T, Mizuno Y, Kikuchi S, Kuno S, Hasegawa K, Hattori N, Mochizuki H, Mori H, Murata M, Nomoto M, Takahashi R, Takeda A, Tsuboi Y, Ugawa Y, et al. Official Japanese Version of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale: validation against the original English version. Movement Disorders Clinical Practice (Hoboken, N.J.). 1: 200-212. PMID 25328906 DOI: 10.1002/Mdc3.12058 |
0.311 |
|
| 2014 |
Miura E, Hasegawa T, Konno M, Suzuki M, Sugeno N, Fujikake N, Geisler S, Tabuchi M, Oshima R, Kikuchi A, Baba T, Wada K, Nagai Y, Takeda A, Aoki M. VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease. Neurobiology of Disease. 71: 1-13. PMID 25107340 DOI: 10.1016/J.Nbd.2014.07.014 |
0.394 |
|
| 2014 |
Kikuchi A, Baba T, Hasegawa T, Sugeno N, Konno M, Miura E, Oshima R, Aoki M, Takeda A. Improvement of freezing of gait in patients with Parkinson's disease by imagining bicycling. Case Reports in Neurology. 6: 92-5. PMID 24761145 DOI: 10.1159/000362119 |
0.312 |
|
| 2014 |
Takeda A, Baba T, Kikuchi A, Hasegawa T, Sugeno N, Konno M, Miura E, Mori E. Olfactory dysfunction and dementia in Parkinson's disease. Journal of Parkinson's Disease. 4: 181-7. PMID 24625830 DOI: 10.3233/Jpd-130277 |
0.369 |
|
| 2013 |
Takeda A. [Severe olfactory dysfunction is a predictor of dementia with Parkinson's disease]. Rinshå Shinkeigaku = Clinical Neurology. 53: 91-7. PMID 23470887 DOI: 10.5692/Clinicalneurol.53.91 |
0.359 |
|
| 2013 |
Kikuchi A, Baba T, Hasegawa T, Kobayashi M, Sugeno N, Konno M, Miura E, Hosokai Y, Ishioka T, Nishio Y, Hirayama K, Suzuki K, Aoki M, Takahashi S, Fukuda H, ... ... Takeda A, et al. Hypometabolism in the supplementary and anterior cingulate cortices is related to dysphagia in Parkinson's disease: a cross-sectional and 3-year longitudinal cohort study. Bmj Open. 3. PMID 23457325 DOI: 10.1136/Bmjopen-2012-002249 |
0.301 |
|
| 2013 |
Hasegawa T, Kikuchi A, Takeda A. Pathogenesis of multiple system atrophy Neurology and Clinical Neuroscience. 1: 189-194. DOI: 10.1111/Ncn3.57 |
0.459 |
|
| 2012 |
Konno M, Hasegawa T, Baba T, Miura E, Sugeno N, Kikuchi A, Fiesel FC, Sasaki T, Aoki M, Itoyama Y, Takeda A. Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy. Molecular Neurodegeneration. 7: 38. PMID 22892036 DOI: 10.1186/1750-1326-7-38 |
0.355 |
|
| 2012 |
Hiraoka K, Okamura N, Funaki Y, Hayashi A, Tashiro M, Hisanaga K, Fujii T, Takeda A, Yanai K, Iwata R, Mori E. Cholinergic deficit and response to donepezil therapy in Parkinson's disease with dementia. European Neurology. 68: 137-43. PMID 22832236 DOI: 10.1159/000338774 |
0.354 |
|
| 2012 |
Baba T, Kikuchi A, Hirayama K, Nishio Y, Hosokai Y, Kanno S, Hasegawa T, Sugeno N, Konno M, Suzuki K, Takahashi S, Fukuda H, Aoki M, Itoyama Y, Mori E, ... Takeda A, et al. Severe olfactory dysfunction is a prodromal symptom of dementia associated with Parkinson's disease: a 3 year longitudinal study. Brain : a Journal of Neurology. 135: 161-9. PMID 22287381 DOI: 10.1093/Brain/Awr321 |
0.411 |
|
| 2012 |
Hiraoka K, Okamura N, Funaki Y, Hayashi A, Tashiro M, Hisanaga K, Fujii T, Takeda A, Yanai K, Iwata R, Mori E. Cholinergic Deficit and Response to Donepezil Therapy in Parkinson's Disease with Dementia: [5-11C-Methoxy]donepezil-PET Study (P04.189) Neurology. 78. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P04.189 |
0.361 |
|
| 2012 |
Iwasaki K, Kikuchi A, Takeda A, Satoh T, Sawada J-, Konno H, Takahashi T, Takayama S, Tobita M, Yaegashi N. 1.257 A Crossover Study Of A Traditional Asian Herbal Medicine For Huntington'S Disease Parkinsonism & Related Disorders. 18. DOI: 10.1016/S1353-8020(11)70315-7 |
0.384 |
|
| 2011 |
Takeda A. [Parkinson's disease with dementia (PDD)]. Nihon Rinsho. Japanese Journal of Clinical Medicine. 69: 350-5. PMID 22755212 |
0.326 |
|
| 2011 |
Hasegawa T, Konno M, Baba T, Sugeno N, Kikuchi A, Kobayashi M, Miura E, Tanaka N, Tamai K, Furukawa K, Arai H, Mori F, Wakabayashi K, Aoki M, Itoyama Y, ... Takeda A, et al. The AAA-ATPase VPS4 regulates extracellular secretion and lysosomal targeting of α-synuclein. Plos One. 6: e29460. PMID 22216284 DOI: 10.1371/Journal.Pone.0029460 |
0.383 |
|
| 2010 |
Hasegawa T, Baba T, Kobayashi M, Konno M, Sugeno N, Kikuchi A, Itoyama Y, Takeda A. Role of TPPP/p25 on α-synuclein-mediated oligodendroglial degeneration and the protective effect of SIRT2 inhibition in a cellular model of multiple system atrophy. Neurochemistry International. 57: 857-66. PMID 20849899 DOI: 10.1016/J.Neuint.2010.09.002 |
0.355 |
|
| 2010 |
Nishio Y, Hirayama K, Takeda A, Hosokai Y, Ishioka T, Suzuki K, Itoyama Y, Takahashi S, Mori E. Corticolimbic gray matter loss in Parkinson's disease without dementia. European Journal of Neurology. 17: 1090-7. PMID 20298422 DOI: 10.1111/J.1468-1331.2010.02980.X |
0.403 |
|
| 2009 |
Takeda A, Baba T, Kikuchi A, Sugeno N, Hasegawa T, Itoyama Y, Ishioka T, Hirayama K, Mori E. [Pathophysiological process underlying Parkinson's disease: motor & non-motor symptoms]. Rinshō Shinkeigaku = Clinical Neurology. 49: 888-9. PMID 20030239 DOI: 10.5692/Clinicalneurol.49.888 |
0.302 |
|
| 2009 |
Satake W, Nakabayashi Y, Mizuta I, Hirota Y, Ito C, Kubo M, Kawaguchi T, Tsunoda T, Watanabe M, Takeda A, Tomiyama H, Nakashima K, Hasegawa K, Obata F, Yoshikawa T, et al. Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nature Genetics. 41: 1303-7. PMID 19915576 DOI: 10.1038/Ng.485 |
0.309 |
|
| 2009 |
Su B, Liu H, Wang X, Chen SG, Siedlak SL, Kondo E, Choi R, Takeda A, Castellani RJ, Perry G, Smith MA, Zhu X, Lee HG. Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease. Molecular Neurodegeneration. 4: 32. PMID 19627592 DOI: 10.1186/1750-1326-4-32 |
0.751 |
|
| 2009 |
Abe N, Fujii T, Hirayama K, Takeda A, Hosokai Y, Ishioka T, Nishio Y, Suzuki K, Itoyama Y, Takahashi S, Fukuda H, Mori E. Do parkinsonian patients have trouble telling lies? The neurobiological basis of deceptive behaviour Brain. 132: 1386-1395. PMID 19339257 DOI: 10.1093/Brain/Awp052 |
0.355 |
|
| 2009 |
Hosokai Y, Nishio Y, Hirayama K, Takeda A, Ishioka T, Sawada Y, Suzuki K, Itoyama Y, Takahashi S, Fukuda H, Mori E. Distinct patterns of regional cerebral glucose metabolism in Parkinson's disease with and without mild cognitive impairment. Movement Disorders : Official Journal of the Movement Disorder Society. 24: 854-62. PMID 19199357 DOI: 10.1002/Mds.22444 |
0.314 |
|
| 2009 |
Friedlich AL, Smith MA, Zhu X, Takeda A, Nunomura A, Moreira PI, Perry G. Oxidative Stress in Parkinson`s Disease The Open Pathology Journal. 3: 38-42. DOI: 10.2174/1874375700903010038 |
0.806 |
|
| 2008 |
Castellani RJ, Nunomura A, Rolston RK, Moreira PI, Takeda A, Perry G, Smith MA. Sublethal RNA oxidation as a mechanism for neurodegenerative disease. International Journal of Molecular Sciences. 9: 789-806. PMID 19325784 DOI: 10.3390/Ijms9050789 |
0.75 |
|
| 2008 |
Mizuta I, Tsunoda T, Satake W, Nakabayashi Y, Watanabe M, Takeda A, Hasegawa K, Nakashima K, Yamamoto M, Hattori N, Murata M, Toda T. Calbindin 1, fibroblast growth factor 20, and α-synuclein in sporadic Parkinson’s disease Human Genetics. 124: 89-94. PMID 18568448 DOI: 10.1007/S00439-008-0525-5 |
0.316 |
|
| 2008 |
Sugeno N, Takeda A, Hasegawa T, Kobayashi M, Kikuchi A, Mori F, Wakabayashi K, Itoyama Y. Serine 129 Phosphorylation of α-Synuclein Induces Unfolded Protein Response-mediated Cell Death Journal of Biological Chemistry. 283: 23179-23188. PMID 18562315 DOI: 10.1074/Jbc.M802223200 |
0.313 |
|
| 2008 |
Ning YP, Kanai K, Tomiyama H, Li Y, Funayama M, Yoshino H, Sato S, Asahina M, Kuwabara S, Takeda A, Hattori T, Mizuno Y, Hattori N. PARK9-linked parkinsonism in eastern Asia: mutation detection in ATP13A2 and clinical phenotype. Neurology. 70: 1491-3. PMID 18413573 DOI: 10.1212/01.Wnl.0000310427.72236.68 |
0.305 |
|
| 2008 |
Moreira PI, Nunomura A, Nakamura M, Takeda A, Shenk JC, Aliev G, Smith MA, Perry G. Nucleic acid oxidation in Alzheimer disease. Free Radical Biology & Medicine. 44: 1493-505. PMID 18258207 DOI: 10.1016/J.Freeradbiomed.2008.01.002 |
0.758 |
|
| 2007 |
Nunomura A, Moreira PI, Takeda A, Smith MA, Perry G. Oxidative RNA damage and neurodegeneration. Current Medicinal Chemistry. 14: 2968-75. PMID 18220733 DOI: 10.2174/092986707782794078 |
0.741 |
|
| 2007 |
Satake W, Mizuta I, Suzuki S, Nakabayashi Y, Ito C, Watanabe M, Takeda A, Hasegawa K, Sakoda S, Yamamoto M, Hattori N, Murata M, Toda T. Fibroblast growth factor 20 gene and Parkinson's disease in the Japanese population. Neuroreport. 18: 937-940. PMID 17515805 DOI: 10.1097/Wnr.0B013E328133265B |
0.353 |
|
| 2007 |
Hasegawa T, Sugeno N, Takeda A, Matsuzaki-Kobayashi M, Kikuchi A, Furukawa K, Miyagi T, Itoyama Y. Role of Neu4L sialidase and its substrate ganglioside GD3 in neuronal apoptosis induced by catechol metabolites. Febs Letters. 581: 406-412. PMID 17234188 DOI: 10.1016/J.Febslet.2006.12.046 |
0.302 |
|
| 2007 |
Takeda A, Kikuchi A, Matsuzaki-Kobayashi M, Sugeno N, Itoyama Y. Olfactory dysfunction in Parkinson's disease Journal of Neurology. 254: IV2-IV7. DOI: 10.1007/S00415-007-4002-1 |
0.329 |
|
| 2006 |
Nunomura A, Honda K, Takeda A, Hirai K, Zhu X, Smith MA, Perry G. Oxidative damage to RNA in neurodegenerative diseases. Journal of Biomedicine & Biotechnology. 2006: 82323. PMID 17047315 DOI: 10.1155/Jbb/2006/82323 |
0.807 |
|
| 2006 |
Takeda A, Hasegawa T, Matsuzaki-Kobayashi M, Sugeno N, Kikuchi A, Itoyama Y, Furukawa K. Mechanisms of neuronal death in synucleinopathy. Biomed Research International. 2006: 19365-19365. PMID 17047300 DOI: 10.1155/Jbb/2006/19365 |
0.356 |
|
| 2006 |
Lee HG, Zhu X, Takeda A, Perry G, Smith MA. Emerging evidence for the neuroprotective role of alpha-synuclein. Experimental Neurology. 200: 1-7. PMID 16780837 DOI: 10.1016/J.Expneurol.2006.04.024 |
0.705 |
|
| 2006 |
Furukawa K, Matsuzaki-Kobayashi M, Hasegawa T, Kikuchi A, Sugeno N, Itoyama Y, Wang Y, Yao PJ, Bushlin I, Takeda A. Plasma membrane ion permeability induced by mutant alpha-synuclein contributes to the degeneration of neural cells. Journal of Neurochemistry. 97: 1071-7. PMID 16606366 DOI: 10.1111/J.1471-4159.2006.03803.X |
0.303 |
|
| 2006 |
Hasegawa T, Matsuzaki-Kobayashi M, Takeda A, Sugeno N, Kikuchi A, Furukawa K, Perry G, Smith MA, Itoyama Y. Alpha-synuclein facilitates the toxicity of oxidized catechol metabolites: implications for selective neurodegeneration in Parkinson's disease. Febs Letters. 580: 2147-52. PMID 16567160 DOI: 10.1016/J.Febslet.2006.03.018 |
0.632 |
|
| 2005 |
Dwyer BE, Takeda A, Zhu X, Perry G, Smith MA. Ferric cycle activity and Alzheimer disease. Current Neurovascular Research. 2: 261-7. PMID 16181119 DOI: 10.2174/1567202054368371 |
0.747 |
|
| 2005 |
Lee HG, Perry G, Moreira PI, Garrett MR, Liu Q, Zhu X, Takeda A, Nunomura A, Smith MA. Tau phosphorylation in Alzheimer's disease: pathogen or protector? Trends in Molecular Medicine. 11: 164-9. PMID 15823754 DOI: 10.1016/J.Molmed.2005.02.008 |
0.832 |
|
| 2005 |
Liu Q, Smith MA, Avilá J, DeBernardis J, Kansal M, Takeda A, Zhu X, Nunomura A, Honda K, Moreira PI, Oliveira CR, Santos MS, Shimohama S, Aliev G, de la Torre J, et al. Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. Free Radical Biology & Medicine. 38: 746-54. PMID 15721985 DOI: 10.1016/J.Freeradbiomed.2004.11.005 |
0.797 |
|
| 2005 |
Liu Q, Lee HG, Honda K, Siedlak SL, Harris PL, Cash AD, Zhu X, Avila J, Nunomura A, Takeda A, Smith MA, Perry G. Tau modifiers as therapeutic targets for Alzheimer's disease. Biochimica Et Biophysica Acta. 1739: 211-5. PMID 15615639 DOI: 10.1016/J.Bbadis.2004.06.021 |
0.827 |
|
| 2004 |
Nunomura A, Chiba S, Lippa CF, Cras P, Kalaria RN, Takeda A, Honda K, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease. Neurobiology of Disease. 17: 108-13. PMID 15350971 DOI: 10.1016/J.Nbd.2004.06.003 |
0.754 |
|
| 2004 |
Takeda A, Itoyama Y, Kimpara T, Zhu X, Avila J, Dwyer BE, Perry G, Smith MA. Heme catabolism and heme oxygenase in neurodegenerative disease. Antioxidants & Redox Signaling. 6: 888-94. PMID 15345149 DOI: 10.1089/Ars.2004.6.888 |
0.739 |
|
| 2004 |
Lee HG, Casadesus G, Zhu X, Takeda A, Perry G, Smith MA. Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease. Annals of the New York Academy of Sciences. 1019: 1-4. PMID 15246983 DOI: 10.1196/Annals.1297.001 |
0.76 |
|
| 2004 |
Hasegawa T, Matsuzaki M, Takeda A, Kikuchi A, Akita H, Perry G, Smith MA, Itoyama Y. Accelerated alpha-synuclein aggregation after differentiation of SH-SY5Y neuroblastoma cells. Brain Research. 1013: 51-9. PMID 15196967 DOI: 10.1016/J.Brainres.2004.04.018 |
0.603 |
|
| 2004 |
Matsuzaki M, Hasegawa T, Takeda A, Kikuchi A, Furukawa K, Kato Y, Itoyama Y. Histochemical features of stress-induced aggregates in α-synuclein overexpressing cells Brain Research. 1004: 83-90. PMID 15033422 DOI: 10.1016/J.Brainres.2004.01.017 |
0.381 |
|
| 2004 |
Masaki T, Matsushita S, Arai H, Takeda A, Itoyama Y, Mochizuki H, Kamakura K, Ohara S, Higuchi S. Association between a polymorphism of brain-derived neurotrophic factor gene and sporadic Parkinson's disease. Annals of Neurology. 54: 276-7. PMID 12891687 DOI: 10.1002/Ana.10665 |
0.342 |
|
| 2003 |
Tateyama M, Saito N, Fujihara K, Shiga Y, Takeda A, Narikawa K, Hasegawa T, Taguchi Y, Sakuma R, Onodera Y, Ohnuma A, Tobita M, Itoyama Y. Familial inclusion body myositis: a report on two Japanese sisters. Internal Medicine (Tokyo, Japan). 42: 1035-8. PMID 14606722 DOI: 10.2169/Internalmedicine.42.1035 |
0.327 |
|
| 2003 |
Hasegawa T, Matsuzaki M, Takeda A, Kikuchi A, Furukawa K, Shibahara S, Itoyama Y. Increased dopamine and its metabolites in SH-SY5Y neuroblastoma cells that express tyrosinase Journal of Neurochemistry. 87: 470-475. PMID 14511124 DOI: 10.1046/J.1471-4159.2003.02008.X |
0.311 |
|
| 2003 |
Tateyama M, Takeda A, Onodera Y, Matsuzaki M, Hasegawa T, Nunomura A, Hirai K, Perry G, Smith MA, Itoyama Y. Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles. Acta Neuropathologica. 105: 581-5. PMID 12734664 DOI: 10.1007/S00401-003-0685-2 |
0.718 |
|
| 2002 |
Perry G, Nunomura A, Hirai K, Zhu X, Pérez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A, Smith MA. Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radical Biology & Medicine. 33: 1475-9. PMID 12446204 DOI: 10.1016/S0891-5849(02)01113-9 |
0.82 |
|
| 2002 |
Nunomura A, Chiba S, Kosaka K, Takeda A, Castellani RJ, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies. Neuroreport. 13: 2035-9. PMID 12438921 DOI: 10.1097/00001756-200211150-00009 |
0.752 |
|
| 2002 |
Castellani R, Hirai K, Aliev G, Drew KL, Nunomura A, Takeda A, Cash AD, Obrenovich ME, Perry G, Smith MA. Role of mitochondrial dysfunction in Alzheimer's disease. Journal of Neuroscience Research. 70: 357-60. PMID 12391597 DOI: 10.1002/Jnr.10389 |
0.804 |
|
| 2002 |
Kikuchi A, Takeda A, Onodera H, Kimpara T, Hisanaga K, Sato N, Nunomura A, Castellani RJ, Perry G, Smith MA, Itoyama Y. Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy. Neurobiology of Disease. 9: 244-8. PMID 11895375 DOI: 10.1006/Nbdi.2002.0466 |
0.735 |
|
| 2002 |
Smith MA, Drew KL, Nunomura A, Takeda A, Hirai K, Zhu X, Atwood CS, Raina AK, Rottkamp CA, Sayre LM, Friedland RP, Perry G. Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs? Neurochemistry International. 40: 527-31. PMID 11850109 DOI: 10.1016/S0197-0186(01)00123-1 |
0.803 |
|
| 2001 |
Kikuchi A, Takeda A, Kimpara T, Nakagawa M, Kawashima R, Sugiura M, Kinomura S, Fukuda H, Chida K, Okita N, Takase S, Itoyama Y. Hypoperfusion in the supplementary motor area, dorsolateral prefrontal cortex and insular cortex in Parkinson's disease. Journal of the Neurological Sciences. 193: 29-36. PMID 11718747 DOI: 10.1016/S0022-510X(01)00641-4 |
0.333 |
|
| 2001 |
Zhu X, Rottkamp CA, Hartzler A, Sun Z, Takeda A, Boux H, Shimohama S, Perry G, Smith MA. Activation of MKK6, an upstream activator of p38, in Alzheimer's disease. Journal of Neurochemistry. 79: 311-8. PMID 11677259 DOI: 10.1046/J.1471-4159.2001.00597.X |
0.706 |
|
| 2001 |
Zhu X, Castellani RJ, Takeda A, Nunomura A, Atwood CS, Perry G, Smith MA. Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis. Mechanisms of Ageing and Development. 123: 39-46. PMID 11640950 DOI: 10.1016/S0047-6374(01)00342-6 |
0.773 |
|
| 2001 |
Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA. Oxidative damage is the earliest event in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 60: 759-67. PMID 11487050 DOI: 10.1093/Jnen/60.8.759 |
0.798 |
|
| 2001 |
Okamura N, Arai H, Higuchi M, Tashiro M, Matsui T, Hu X, Takeda A, Itoh M, Sasaki H. [18F]FDG-PET study in dementia with Lewy bodies and Alzheimer's disease. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 25: 447-456. PMID 11294488 DOI: 10.1016/S0278-5846(01)80005-1 |
0.344 |
|
| 2001 |
Takeda A, Fujihara K, Kikuchi A, Kimpara T, Itoyama Y. Dementia in Parkinson's Disease: Its Incidence and a Possible Relationship with Dopa‐refractory Symptoms Psychogeriatrics. 1: 119-122. DOI: 10.1111/J.1479-8301.2001.Tb00005.X |
0.356 |
|
| 2000 |
Smith MA, Nunomura A, Zhu X, Takeda A, Perry G. Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease. Antioxidants & Redox Signaling. 2: 413-20. PMID 11229355 DOI: 10.1089/15230860050192198 |
0.759 |
|
| 2000 |
Kanda A, Ebihara S, Arai H, Takeda A, Sasaki H. Parkinson's disease and impaired chemosensitivity to hypoxia. The Lancet. 356: 2100. PMID 11145519 DOI: 10.1016/S0140-6736(05)74310-5 |
0.406 |
|
| 2000 |
Zhu X, Rottkamp CA, Boux H, Takeda A, Perry G, Smith MA. Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 59: 880-8. PMID 11079778 DOI: 10.1093/JNEN/59.10.880 |
0.721 |
|
| 2000 |
Tateyama M, Tobita M, Takeda A, Chida K, Onodera Y, Kikuchi A, Aoyagi N, Itoyama Y. DNA single-strand breaks are increased in muscle diseases with rimmed vacuoles. Acta Neuropathologica. 100: 390-394. PMID 10985697 DOI: 10.1007/S004010000192 |
0.31 |
|
| 2000 |
Takeda A, Smith MA, Avilá J, Nunomura A, Siedlak SL, Zhu X, Perry G, Sayre LM. In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification. Journal of Neurochemistry. 75: 1234-41. PMID 10936206 DOI: 10.1046/J.1471-4159.2000.0751234.X |
0.799 |
|
| 2000 |
Kimpara T, Takeda A, Yamaguchi T, Arai H, Okita N, Takase S, Sasaki H, Itoyama Y. Increased bilirubins and their derivatives in cerebrospinal fluid in Alzheimer’s disease Neurobiology of Aging. 21: 551-554. PMID 10924768 DOI: 10.1016/S0197-4580(00)00128-7 |
0.385 |
|
| 2000 |
Raina AK, Zhu X, Rottkamp CA, Monteiro M, Takeda A, Smith MA. Cyclin' toward dementia: cell cycle abnormalities and abortive oncogenesis in Alzheimer disease. Journal of Neuroscience Research. 61: 128-33. PMID 10878584 DOI: 10.1002/1097-4547(20000715)61:2<128::Aid-Jnr2>3.0.Co;2-H |
0.709 |
|
| 2000 |
Zhu X, Raina AK, Boux H, Simmons ZL, Takeda A, Smith MA. Activation of oncogenic pathways in degenerating neurons in Alzheimer disease. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 18: 433-7. PMID 10817927 DOI: 10.1016/S0736-5748(00)00010-1 |
0.745 |
|
| 2000 |
Perry G, Nunomura A, Hirai K, Takeda A, Aliev G, Smith MA. Oxidative damage in Alzheimer's disease: the metabolic dimension. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 18: 417-21. PMID 10817925 DOI: 10.1016/S0736-5748(00)00006-X |
0.787 |
|
| 2000 |
Higuchi S, Matsushita S, Nakane J, Arai H, Matsui T, Urakami K, Yuzuriha T, Takeda A. Alpha2-macroglobulin gene polymorphisms show racial diversity and are not associated with Alzheimer's disease. Neuroreport. 11: 1167-1171. PMID 10817585 DOI: 10.1097/00001756-200004270-00005 |
0.389 |
|
| 2000 |
Raina AK, Zhu X, Monteiro M, Takeda A, Smith MA. Abortive oncogeny and cell cycle-mediated events in Alzheimer disease. Progress in Cell Cycle Research. 4: 235-42. PMID 10740829 DOI: 10.1007/978-1-4615-4253-7_20 |
0.733 |
|
| 2000 |
Gerst JL, Raina AK, Pirim I, McShea A, Harris PL, Siedlak SL, Takeda A, Petersen RB, Smith MA. Altered cell-matrix associated ADAM proteins in Alzheimer disease. Journal of Neuroscience Research. 59: 680-4. PMID 10686596 DOI: 10.1002/(Sici)1097-4547(20000301)59:5<680::Aid-Jnr11>3.0.Co;2-6 |
0.737 |
|
| 2000 |
Takeda A, Perry G, Abraham NG, Dwyer BE, Kutty RK, Laitinen JT, Petersen RB, Smith MA. Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau. The Journal of Biological Chemistry. 275: 5395-9. PMID 10681514 DOI: 10.1074/Jbc.275.8.5395 |
0.654 |
|
| 2000 |
Zhu X, Raina AK, Rottkamp CA, Boux H, Siedlak SL, Takeda A, Perry G, Smith MA. Activation of P38 kinase links π phosphorylation, oxidative stress and cell cycle-related events in Alzheimer disease Neurobiology of Aging. 21: 267. DOI: 10.1016/S0197-4580(00)83154-1 |
0.759 |
|
| 1999 |
Nunomura A, Perry G, Hirai K, Aliev G, Takeda A, Chiba S, Smith MA. Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome. Annals of the New York Academy of Sciences. 893: 362-4. PMID 10672267 DOI: 10.1111/J.1749-6632.1999.Tb07855.X |
0.782 |
|
| 1999 |
Raina AK, Takeda A, Smith MA. Mitotic neurons: a dogma succumbs. Experimental Neurology. 159: 248-9. PMID 10486192 DOI: 10.1006/Exnr.1999.7141 |
0.569 |
|
| 1999 |
Smith MA, Nunomura A, Takeda A, Perry G. Asking the right questions. Science (New York, N.Y.). 285: 665. PMID 10454920 DOI: 10.1126/Science.285.5428.663E |
0.649 |
|
| 1999 |
Perry G, Roder H, Nunomura A, Takeda A, Friedlich AL, Zhu X, Raina AK, Holbrook N, Siedlak SL, Harris PL, Smith MA. Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation. Neuroreport. 10: 2411-5. PMID 10439473 DOI: 10.1097/00001756-199908020-00035 |
0.803 |
|
| 1999 |
Raina AK, Takeda A, Nunomura A, Perry G, Smith MA. Genetic evidence for oxidative stress in Alzheimer's disease. Neuroreport. 10: 1355-7. PMID 10363952 DOI: 10.1097/00001756-199904260-00036 |
0.795 |
|
| 1999 |
Takeda A, Petersen RB, Smith MA. Effect Of Chronic Expression Of Heme Oxygenase-1 In Neuronal Cells: Possible Interaction With Tau Journal of Neuropathology and Experimental Neurology. 58: 531. DOI: 10.1097/00005072-199905000-00100 |
0.329 |
|
| 1999 |
NUNOMURA A, PERRY G, ZHANG J, MONTINE TJ, TAKEDA A, CHIBA S, SMITH MA. RNA Oxidation in Alzheimer and Parkinson Diseases Journal of Anti-Aging Medicine. 2: 227-230. DOI: 10.1089/Rej.1.1999.2.227 |
0.747 |
|
| 1998 |
Higuchi S, Arai H, Matsushita S, Matsui T, Kimpara T, Takeda A, Shirakura K. BRIEF COMMUNICATION Mutation in the α-Synuclein Gene and Sporadic Parkinson's Disease, Alzheimer's Disease, and Dementia with Lewy Bodies Experimental Neurology. 153: 164-166. PMID 9743579 DOI: 10.1006/Exnr.1998.6868 |
0.402 |
|
| 1998 |
Kimpara T, Takeda A, Okita N, Takase S, Saito H, Itoyama Y. The familial parkinsonism locus on chromosome 4 and idiopathic Parkinson's disease in Japan. Journal of Neurology, Neurosurgery, and Psychiatry. 64: 416-7. PMID 9527174 DOI: 10.1136/Jnnp.64.3.416 |
0.452 |
|
| 1997 |
Kimpara T, Takeda A, Watanabe K, Itoyama Y, Ikawa S, Watanabe M, Arai H, Sasaki H, Higuchi S, Okita N, Takase S, Saito H, Takahashi K, Shibahara S. Microsatellite polymorphism in the human heme oxygenase-1 gene promoter and its application in association studies with Alzheimer and Parkinson disease Human Genetics. 100: 145-147. PMID 9225984 DOI: 10.1007/S004390050480 |
0.443 |
|
| 1996 |
Takeda A, Kimpara T, Onodera H, Itoyama Y, Shibahara S, Kogure K. Regional difference in induction of heme oxygenase-1 protein following rat transient forebrain ischemia Neuroscience Letters. 205: 169-172. PMID 8852585 DOI: 10.1016/0304-3940(96)12405-8 |
0.31 |
|
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