Peter L. Pedersen - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
General Biophysics, Biochemistry

126 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Ko YH, Niedźwiecka K, Casal M, Pedersen PL, Ułaszewski S. 3-Bromopyruvate (3BP) as a Potent Anticancer Therapy in Honor and Memory of the Late Professor André Goffeau. Yeast (Chichester, England). PMID 30462852 DOI: 10.1002/Yea.3367  0.329
2016 Lis P, Dyląg M, Niedźwiecka K, Ko YH, Pedersen PL, Goffeau A, Ułaszewski S. The HK2 Dependent "Warburg Effect" and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate. Molecules (Basel, Switzerland). 21. PMID 27983708 DOI: 10.3390/Molecules21121730  0.319
2016 Lis P, Jurkiewicz P, Cal-Bä Kowska M, Ko YH, Pedersen PL, Goffeau A, Uå Aszewski SA. Screening the yeast genome for energetic metabolism pathways involved in a phenotypic response to the anti-cancer agent 3-bromopyruvate. Oncotarget. PMID 26862728 DOI: 10.18632/Oncotarget.7174  0.366
2012 Pedersen PL. 3-Bromopyruvate (3BP) a fast acting, promising, powerful, specific, and effective "small molecule" anti-cancer agent taken from labside to bedside: introduction to a special issue. Journal of Bioenergetics and Biomembranes. 44: 1-6. PMID 22382780 DOI: 10.1007/S10863-012-9425-4  0.353
2012 Blum DJ, Ko YH, Pedersen PL. Mitochondrial ATP synthase catalytic mechanism: a novel visual comparative structural approach emphasizes pivotal roles for Mg²⁺ and P-loop residues in making ATP. Biochemistry. 51: 1532-46. PMID 22243519 DOI: 10.1021/Bi201595V  0.457
2011 Chen YB, Aon MA, Hsu YT, Soane L, Teng X, McCaffery JM, Cheng WC, Qi B, Li H, Alavian KN, Dayhoff-Brannigan M, Zou S, Pineda FJ, O'Rourke B, Ko YH, ... Pedersen PL, et al. Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential. The Journal of Cell Biology. 195: 263-76. PMID 21987637 DOI: 10.1083/Jcb.201108059  0.375
2009 Pedersen PL. Mitochondrial matters of the heart: a plethora of regulatory modes to maintain function for a long lifetime. Journal of Bioenergetics and Biomembranes. 41: 95-8. PMID 19513821 DOI: 10.1007/S10863-009-9219-5  0.322
2009 Mathupala SP, Ko YH, Pedersen PL. Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy. Seminars in Cancer Biology. 19: 17-24. PMID 19101634 DOI: 10.1016/J.Semcancer.2008.11.006  0.368
2008 Hong S, Pedersen PL. ATP synthase and the actions of inhibitors utilized to study its roles in human health, disease, and other scientific areas. Microbiology and Molecular Biology Reviews : Mmbr. 72: 590-641, Table of Co. PMID 19052322 DOI: 10.1128/Mmbr.00016-08  0.41
2008 Pedersen PL. Voltage dependent anion channels (VDACs): a brief introduction with a focus on the outer mitochondrial compartment's roles together with hexokinase-2 in the "Warburg effect" in cancer. Journal of Bioenergetics and Biomembranes. 40: 123-6. PMID 18780167 DOI: 10.1007/S10863-008-9165-7  0.389
2007 Pedersen PL. Transport ATPases into the year 2008: a brief overview related to types, structures, functions and roles in health and disease. Journal of Bioenergetics and Biomembranes. 39: 349-55. PMID 18175209 DOI: 10.1007/S10863-007-9123-9  0.42
2007 Pedersen PL. Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers' most common phenotypes, the "Warburg Effect", i.e., elevated glycolysis in the presence of oxygen. Journal of Bioenergetics and Biomembranes. 39: 211-22. PMID 17879147 DOI: 10.1007/S10863-007-9094-X  0.332
2006 Mathupala SP, Ko YH, Pedersen PL. Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria. Oncogene. 25: 4777-86. PMID 16892090 DOI: 10.1038/Sj.Onc.1209603  0.369
2006 Chen C, Saxena AK, Simcoke WN, Garboczi DN, Pedersen PL, Ko YH. Mitochondrial ATP synthase. Crystal structure of the catalytic F1 unit in a vanadate-induced transition-like state and implications for mechanism. The Journal of Biological Chemistry. 281: 13777-83. PMID 16531409 DOI: 10.1074/Jbc.M513369200  0.506
2005 Pedersen PL. Transport ATPases: structure, motors, mechanism and medicine: a brief overview. Journal of Bioenergetics and Biomembranes. 37: 349-57. PMID 16691464 DOI: 10.1007/S10863-005-9470-3  0.362
2004 Hong S, Pedersen PL. Mitochondrial ATP synthase: a bioinformatic approach reveals new insights about the roles of supernumerary subunits g and A6L. Journal of Bioenergetics and Biomembranes. 36: 515-23. PMID 15692730 DOI: 10.1007/S10863-004-8998-Y  0.39
2004 Chen C, Ko Y, Delannoy M, Ludtke SJ, Chiu W, Pedersen PL. Mitochondrial ATP synthasome: three-dimensional structure by electron microscopy of the ATP synthase in complex formation with carriers for Pi and ADP/ATP. The Journal of Biological Chemistry. 279: 31761-8. PMID 15166242 DOI: 10.1074/Jbc.M401353200  0.485
2003 Hong S, Pedersen PL. ATP synthases: insights into their motor functions from sequence and structural analyses. Journal of Bioenergetics and Biomembranes. 35: 95-120. PMID 12887009 DOI: 10.1023/A:1023786618422  0.49
2003 Hong S, Pedersen PL. Subunit E of mitochondrial ATP synthase: a bioinformatic analysis reveals a phosphopeptide binding motif supporting a multifunctional regulatory role and identifies a related human brain protein with the same motif. Proteins. 51: 155-61. PMID 12660984 DOI: 10.1002/Prot.10318  0.392
2003 Ko YH, Delannoy M, Hullihen J, Chiu W, Pedersen PL. Mitochondrial ATP synthasome. Cristae-enriched membranes and a multiwell detergent screening assay yield dispersed single complexes containing the ATP synthase and carriers for Pi and ADP/ATP. The Journal of Biological Chemistry. 278: 12305-9. PMID 12560333 DOI: 10.1074/Jbc.C200703200  0.507
2003 Annereau JP, Ko YH, Pedersen PL. Cystic fibrosis transmembrane conductance regulator: the NBF1+R (nucleotide-binding fold 1 and regulatory domain) segment acting alone catalyses a Co2+/Mn2+/Mg2+-ATPase activity markedly inhibited by both Cd2+ and the transition-state analogue orthovanadate. The Biochemical Journal. 371: 451-62. PMID 12523935 DOI: 10.1042/Bj20021318  0.359
2002 Ko YH, Pan W, Inoue C, Pedersen PL. Signal transduction to mitochondrial ATP synthase: evidence that PDGF-dependent phosphorylation of the delta-subunit occurs in several cell lines, involves tyrosine, and is modulated by lysophosphatidic acid. Mitochondrion. 1: 339-48. PMID 16120288 DOI: 10.1016/S1567-7249(01)00036-8  0.454
2002 Pedersen PL. Transport ATPases in biological systems and relationship to human disease: a brief overview. Journal of Bioenergetics and Biomembranes. 34: 327-32. PMID 12539959 DOI: 10.1023/A:1021249701287  0.323
2002 Hong S, Pedersen PL. ATP synthase of yeast: structural insight into the different inhibitory potencies of two regulatory peptides and identification of a new potential regulator. Archives of Biochemistry and Biophysics. 405: 38-43. PMID 12176055 DOI: 10.1016/S0003-9861(02)00303-X  0.351
2001 Ko YH, Pedersen PL. Cystic fibrosis: a brief look at some highlights of a decade of research focused on elucidating and correcting the molecular basis of the disease. Journal of Bioenergetics and Biomembranes. 33: 513-21. PMID 11804193 DOI: 10.1023/A:1012831322753  0.359
2001 Hong S, Ko YH, Pedersen PL. Rotary catalysis within ATP synthases: a bioinformatic approach provides novel insight into how large pH-dependent movements of the C-terminal helix of subunit c may be accommodated. Archives of Biochemistry and Biophysics. 394: 275-9. PMID 11594742 DOI: 10.1006/Abbi.2001.2549  0.313
2001 Ko YH, Pedersen PL, Geschwind JF. Glucose catabolism in the rabbit VX2 tumor model for liver cancer: characterization and targeting hexokinase. Cancer Letters. 173: 83-91. PMID 11578813 DOI: 10.1016/S0304-3835(01)00667-X  0.303
2001 Blum DJ, Ko YH, Hong S, Rini DA, Pedersen PL. ATP synthase motor components: proposal and animation of two dynamic models for stator function. Biochemical and Biophysical Research Communications. 287: 801-7. PMID 11573932 DOI: 10.1006/Bbrc.2001.5634  0.476
2000 Bianchet MA, Pedersen PL, Amzel LM. Notes on the mechanism of ATP synthesis. Journal of Bioenergetics and Biomembranes. 32: 517-21. PMID 15254387 DOI: 10.1023/A:1005673209883  0.632
2000 Pedersen PL, Ko YH, Hong S. ATP synthases in the year 2000: defining the different levels of mechanism and getting a grip on each. Journal of Bioenergetics and Biomembranes. 32: 423-32. PMID 15254377 DOI: 10.1023/A:1005652605340  0.498
2000 Pedersen PL, Ko YH, Hong S. ATP synthases in the year 2000: evolving views about the structures of these remarkable enzyme complexes. Journal of Bioenergetics and Biomembranes. 32: 325-32. PMID 11768293 DOI: 10.1023/A:1005594800983  0.462
2000 Ko YH, Hullihen J, Hong S, Pedersen PL. Mitochondrial F(0)F(1) ATP synthase. Subunit regions on the F1 motor shielded by F(0), Functional significance, and evidence for an involvement of the unique F(0) subunit F(6). The Journal of Biological Chemistry. 275: 32931-9. PMID 10887193 DOI: 10.1074/Jbc.M004453200  0.478
1999 Pedersen PL. Mitochondrial events in the life and death of animal cells: a brief overview. Journal of Bioenergetics and Biomembranes. 31: 291-304. PMID 10665520 DOI: 10.1023/A:1005453700533  0.339
1999 Ko YH, Hong S, Pedersen PL. Chemical Mechanism of ATP Synthase MAGNESIUM PLAYS A PIVOTAL ROLE IN FORMATION OF THE TRANSITION STATE WHERE ATP IS SYNTHESIZED FROM ADP AND INORGANIC PHOSPHATE Journal of Biological Chemistry. 274: 28853-28856. PMID 10506126 DOI: 10.1074/Jbc.274.41.28853  0.447
1998 Golden TR, Pedersen PL. The Oligomycin Sensitivity Conferring Protein of Rat Liver Mitochondrial ATP Synthase: Arginine 94 Is Important for the Binding of OSCP to F1† Biochemistry. 37: 13871-13881. PMID 9753477 DOI: 10.1021/Bi981120A  0.493
1998 Bianchet MA, Hullihen J, Pedersen PL, Amzel LM. The 2.8-A structure of rat liver F1-ATPase: configuration of a critical intermediate in ATP synthesis/hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 95: 11065-70. PMID 9736690 DOI: 10.1073/pnas.95.19.11065  0.654
1998 Ko YH, Pedersen PL. Overexpression, purification, and function of first nucleotide-binding fold of cystic fibrosis transmembrane conductance regulator Methods in Enzymology. 292: 675-686. PMID 9711591 DOI: 10.1016/S0076-6879(98)92052-3  0.337
1998 Hrycyna CA, Ramachandra M, Ambudkar SV, Ko YH, Pedersen PL, Pastan I, Gottesman MM. Mechanism of action of human P-glycoprotein ATPase activity. Photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two ATP sites. The Journal of Biological Chemistry. 273: 16631-4. PMID 9642211 DOI: 10.1074/Jbc.273.27.16631  0.372
1998 Pan W, Ko YH, Pedersen PL. Delta subunit of rat liver mitochondrial ATP synthase: molecular description and novel insights into the nature of its association with the F1-moiety. Biochemistry. 37: 6911-6923. PMID 9578578 DOI: 10.1021/Bi9800698  0.504
1997 Bianchet MA, Ko YH, Amzel LM, Pedersen PL. Modeling of nucleotide binding domains of ABC transporter proteins based on a F1-ATPase/recA topology: structural model of the nucleotide binding domains of the cystic fibrosis transmembrane conductance regulator (CFTR). Journal of Bioenergetics and Biomembranes. 29: 503-24. PMID 9511935 DOI: 10.1023/A:1022443209010  0.583
1997 Ko YH, Pedersen PL. Frontiers in research on cystic fibrosis: understanding its molecular and chemical basis and relationship to the pathogenesis of the disease. Journal of Bioenergetics and Biomembranes. 29: 417-427. PMID 9511927 DOI: 10.1023/A:1022402105375  0.32
1997 Mathupala SP, Rempel A, Pedersen PL. Aberrant glycolytic metabolism of cancer cells: A remarkable coordination of genetic, transcriptional, post-translational, and mutational events that lead to a critical role for Type II hexokinase Journal of Bioenergetics and Biomembranes. 29: 339-343. PMID 9387094 DOI: 10.1023/A:1022494613613  0.326
1997 Ko YH, Bianchet M, Amzel LM, Pedersen PL. Novel insights into the chemical mechanism of ATP synthase. Evidence that in the transition state the gamma-phosphate of ATP is near the conserved alanine within the P-loop of the beta-subunit. The Journal of Biological Chemistry. 272: 18875-81. PMID 9228065 DOI: 10.1074/Jbc.272.30.18875  0.664
1997 Ko YH, Delannoy M, Pedersen PL. Cystic fibrosis transmembrane conductance regulator: the first nucleotide binding fold targets the membrane with retention of its ATP binding function. Biochemistry. 36: 5053-5064. PMID 9125527 DOI: 10.1021/Bi9630265  0.357
1996 Reynafarje BD, Pedersen PL. ATP synthase. Conditions under which all catalytic sites of the F1 moiety are kinetically equivalent in hydrolyzing ATP. Journal of Biological Chemistry. 271: 32546-32550. PMID 8955079 DOI: 10.1074/Jbc.271.51.32546  0.495
1996 Pedersen PL. Frontiers in ATP synthase research: understanding the relationship between subunit movements and ATP synthesis. Journal of Bioenergetics and Biomembranes. 28: 389-395. PMID 8951084 DOI: 10.1007/Bf02113979  0.441
1996 Lebowitz MS, Pedersen PL. Protein inhibitor of mitochondrial ATP synthase: relationship of inhibitor structure to pH-dependent regulation. Archives of Biochemistry and Biophysics. 330: 342-54. PMID 8660664 DOI: 10.1006/Abbi.1996.0261  0.354
1995 Pedersen PL, Hullihen J, Bianchet M, Amzel LM, Lebowitz MS. Rat liver ATP synthase. Relationship of the unique substructure of the F1 moiety to its nucleotide binding properties, enzymatic states, and crystalline form. The Journal of Biological Chemistry. 270: 1775-84. PMID 7829514 DOI: 10.1074/Jbc.270.4.1775  0.675
1995 Arora KK, Pedersen PL. Glucokinase of Escherichia-coli: Induction in Response to the Stress of Overexpressing Foreign Proteins Archives of Biochemistry and Biophysics. 319: 574-578. PMID 7786044 DOI: 10.1006/Abbi.1995.1333  0.302
1995 Chuang WJ, Abeygunawardana C, Gittis AG, Pedersen PL, Mildvan AS. Solution structure and function in trifluoroethanol of PP-50, an ATP-binding peptide from F1ATPase. Archives of Biochemistry and Biophysics. 319: 110-22. PMID 7771774 DOI: 10.1006/Abbi.1995.1272  0.36
1995 Ko YH, Pedersen PL. The First Nucleotide Binding Fold of the Cystic Fibrosis Transmembrane Conductance Regulator Can Function as an Active ATPase Journal of Biological Chemistry. 270: 22093-22096. PMID 7545672 DOI: 10.1074/Jbc.270.38.22093  0.423
1994 Jabs EW, Thomas PJ, Bernstein M, Coss C, Ferreira GC, Pedersen PL. Chromosomal localization of genes required for the terminal steps of oxidative metabolism: alpha and gamma subunits of ATP synthase and the phosphate carrier. Human Genetics. 93: 600-2. PMID 8168843 DOI: 10.1007/Bf00202832  0.411
1994 Bianchet M, Medjahed D, Hulihen J, Pedersen PL, Amzel LM. The three-dimensional structure of rat liver mitochodria F1-ATPase: X-ray diffraction studies. Biochimica Et Biophysica Acta. 1187: 163-4. PMID 8075110 DOI: 10.1016/0005-2728(94)90103-1  0.583
1994 Barnard JP, Pedersen PL. Alteration of pyruvate metabolism in African trypanosomes during differentiation from bloodstream into insect forms. Archives of Biochemistry and Biophysics. 313: 77-82. PMID 8053690 DOI: 10.1006/Abbi.1994.1361  0.355
1994 Pedersen PL. ATP Synthase: The machine that makes ATP Current Biology. 4: 1138-1141. PMID 7704582 DOI: 10.1016/S0960-9822(00)00257-8  0.443
1993 Lebowitz MS, Pedersen PL. Regulation of the mitochondrial ATP synthase/ATPase complex: cDNA cloning, sequence, overexpression, and secondary structural characterization of a functional protein inhibitor. Archives of Biochemistry and Biophysics. 301: 64-70. PMID 8442667 DOI: 10.1006/Abbi.1993.1115  0.393
1993 Ferreira GC, Pedersen PL. Phosphate transport in mitochondria: past accomplishments, present problems, and future challenges. Journal of Bioenergetics and Biomembranes. 25: 483-92. PMID 8132488 DOI: 10.1007/Bf01108405  0.411
1993 Thomas PJ, Pedersen PL. Effects of the delta F508 mutation on the structure, function, and folding of the first nucleotide-binding domain of CFTR. Journal of Bioenergetics and Biomembranes. 25: 11-9. PMID 7680027 DOI: 10.1007/Bf00768063  0.342
1992 Arora KK, Parry DM, Pedersen PL. Hexokinase receptors: preferential enzyme binding in normal cells to nonmitochondrial sites and in transformed cells to mitochondrial sites. Journal of Bioenergetics and Biomembranes. 24: 47-53. PMID 1506408 DOI: 10.1007/Bf00769530  0.36
1992 Amzel LM, Bianchet MA, Pedersen PL. Quaternary structure of ATP synthases: symmetry and asymmetry in the F1 moiety. Journal of Bioenergetics and Biomembranes. 24: 429-33. PMID 1429535 DOI: 10.1007/Bf00762358  0.648
1992 Pedersen PL, Amzel LM. F-type ATPases. Introduction. Journal of Bioenergetics and Biomembranes. 24: 427-8. PMID 1429534 DOI: 10.1007/Bf00762357  0.593
1992 Chuang WJ, Abeygunawardana C, Pedersen PL, Mildvan AS. Two-dimensional NMR, circular dichroism, and fluorescence studies of PP-50, a synthetic ATP-binding peptide from the beta-subunit of mitochondrial ATP synthase. Biochemistry. 31: 7915-21. PMID 1387322 DOI: 10.1021/Bi00149A024  0.391
1992 Thomas PJ, Bianchet M, Garboczi DN, Hullihen J, Amzel LM, Pedersen PL. ATP synthase: structure-function relationships. Biochimica Et Biophysica Acta. 1101: 228-31. PMID 1385978  0.569
1992 Pedersen PL, Thomas PJ, Garboczi DN, Bianchet M, Amzel LM. F-type ATPases: are nucleotide domains in adenylate kinase appropriate models for nucleotide domains in ATP synthase/ATPase complexes? Annals of the New York Academy of Sciences. 671: 359-65. PMID 1288332 DOI: 10.1111/J.1749-6632.1992.Tb43809.X  0.605
1992 Thomas PJ, Bianchet MA, Garboczi DN, Hullihen J, Amzel ML, Pedersen PL. ATP synthase: structure-function relationships Biochimica Et Biophysica Acta. 1101: 228-231. DOI: 10.1016/S0005-2728(05)80027-1  0.424
1991 Thomas PJ, Shenbagamurthi P, Ysern X, Pedersen PL. Cystic fibrosis transmembrane conductance regulator: nucleotide binding to a synthetic peptide. Science (New York, N.Y.). 251: 555-7. PMID 1703660 DOI: 10.1126/Science.1703660  0.333
1991 Bianchet M, Ysern X, Hullihen J, Pedersen P, Amzel L. Mitochondrial ATP synthase. Quaternary structure of the F1 moiety at 3.6 A determined by x-ray diffraction analysis. Journal of Biological Chemistry. 266: 21197-21201. DOI: 10.1016/s0021-9258(18)54840-7  0.317
1989 Pratt RD, Pedersen PL. Inhibition of Na+-dependent phosphate transport by group-specific covalent reagents in rat kidney brush border membrane vesicles. Evidence for the involvement of tyrosine and sulfhydryl groups on the interior of the membrane. Archives of Biochemistry and Biophysics. 268: 9-19. PMID 2912384 DOI: 10.1016/0003-9861(89)90559-6  0.321
1989 Hanley-Trawick S, Carpen ME, Dunaway-Mariano D, Pedersen PL, Hullihen J. Investigation of the substrate structure and metal cofactor requirements of the rat liver mitochondrial ATP synthase/ATPase complex Archives of Biochemistry and Biophysics. 268: 116-123. PMID 2521440 DOI: 10.1016/0003-9861(89)90571-7  0.504
1988 Barnard JP, Pedersen PL. Purification in a single step and kinetic characterization of the pyruvate kinase of Trypanosoma brucei. Molecular and Biochemical Parasitology. 31: 141-147. PMID 3185619 DOI: 10.1016/0166-6851(88)90165-X  0.348
1988 Ysern X, Amzel LM, Pedersen PL. ATP synthases-Structure of the F1-moiety and its relationship to function and mechanism Journal of Bioenergetics and Biomembranes. 20: 423-450. PMID 2906060 DOI: 10.1007/Bf00762202  0.66
1988 Garboczi DN, Fox AH, Gerring SL, Pedersen PL. Beta subunit of rat liver mitochondrial ATP synthase: cDNA cloning, amino acid sequence, expression in Escherichia coli, and structural relationship to adenylate kinase. Biochemistry. 27: 553-560. PMID 2894849 DOI: 10.1021/Bi00402A008  0.437
1988 Garboczi DN, Hullihen JH, Pedersen PL. Mitochondrial ATP synthase. Overexpression in Escherichia coli of a rat liver beta subunit peptide and its interaction with adenine nucleotides. Journal of Biological Chemistry. 263: 15694-15698. DOI: 10.1016/s0021-9258(19)37643-4  0.303
1987 Pedersen PL, Williams N, Hullihen J. Mitochondrial ATP synthase: dramatic Mg2+-induced alterations in the structure and function of the F1-ATPase moiety. Biochemistry. 26: 8631-8637. PMID 2894844 DOI: 10.1021/Bi00400A021  0.745
1987 Petrone G, Garboczi DN, Pedersen PL. Mitochondrial ATP synthase complex: interaction of its F1 adenosinetriphosphatase moiety with the heavy atom iodine. Biochemistry. 26: 4016-4021. PMID 2888483 DOI: 10.1021/Bi00387A041  0.494
1987 Williams N, Hullihen J, Pedersen PL. Ligand binding studies of the F1 moiety of rat liver ATP synthase: implications about the enzyme's structure and mechanism. Biochemistry. 26: 162-169. PMID 2881576 DOI: 10.1021/Bi00375A023  0.738
1987 Pedersen PL, Carafoli E. Ion motive ATPases. II. Energy coupling and work output Trends in Biochemical Sciences. 12: 186-189. DOI: 10.1016/0968-0004(87)90090-9  0.436
1987 Pedersen PL, Carafoli E. Ion motive ATPases. I. Ubiquity, properties, and significance to cell function Trends in Biochemical Sciences. 12: 146-150. DOI: 10.1016/0968-0004(87)90071-5  0.414
1986 Baker JK, Hullihen JM, Pedersen PL. Selective toxicity of the antimalarial primaquine-evidence for both uncoupling and inhibitory effects of a metabolite on the energetics of mitochondria and its ATP synthase complex. Pharmaceutical Research. 3: 290-3. PMID 24271712 DOI: 10.1023/A:1016363402761  0.407
1986 Anholt RR, Aebi U, Pedersen PL, Snyder SH. Solubilization and reassembly of the mitochondrial benzodiazepine receptor. Biochemistry. 25: 2120-5. PMID 3011077 DOI: 10.1021/Bi00356A041  0.33
1986 Nakashima RA, Mangan PS, Colombini M, Pedersen PL. Hexokinase receptor complex in hepatoma mitochondria: evidence from N,N'-dicyclohexylcarbodiimide-labeling studies for the involvement of the pore-forming protein VDAC. Biochemistry. 25: 1015-21. PMID 3008816 DOI: 10.1021/Bi00353A010  0.406
1986 Williams N, Pedersen PL. [47] Purification of α and β subunits and subunit pairs from rat liver mitochondrial F1-ATPase Methods in Enzymology. 126: 484-489. PMID 2908462 DOI: 10.1016/S0076-6879(86)26049-8  0.724
1986 Williams N, Pedersen PL. Rapid purification of F1-ATPase from rat liver mitochondria using a modified chloroform extraction procedure coupled to high-performance liquid chromatography. Methods in Enzymology. 126: 477-484. PMID 2908461 DOI: 10.1016/S0076-6879(86)26048-6  0.737
1986 Schwerzmann K, Pedersen PL. Regulation of the mitochondrial ATP synthase/ATPase complex. Archives of Biochemistry and Biophysics. 250: 1-18. PMID 2876680 DOI: 10.1016/0003-9861(86)90695-8  0.482
1986 Nakashima RA, Scott LJ, Pedersen PL. The role of mitochondrial hexokinase binding in the abnormal energy metabolism of tumor cell lines. Annals of the New York Academy of Sciences. 488: 438-450. DOI: 10.1111/J.1749-6632.1986.Tb54423.X  0.305
1984 Williams N, Amzel LM, Pedersen PL. Proton ATPase of rat liver mitochondria: A rapid procedure for purification of a stable, reconstitutively active F1 preparation using a modified chloroform method Analytical Biochemistry. 140: 581-588. PMID 6237596 DOI: 10.1016/0003-2697(84)90210-0  0.773
1984 Williams N, Hullihen JM, Pedersen PL. The proton adenosinetriphosphatase complex of rat liver mitochondria. Temperature-dependent dissociation-reassociation of the F1-ATPase subunits. Biochemistry. 23: 780-785. PMID 6231951 DOI: 10.1021/Bi00299A030  0.74
1984 Narayanan P, Amzel LM, O'Toole TB, Pedersen PL. Structure analysis of F1-part of proton translocating ATPase at 3.5 Å resolution Acta Crystallographica Section a Foundations of Crystallography. 40: C7-C7. DOI: 10.1107/S0108767384099591  0.558
1983 Kaplan RS, Pedersen PL. Characterization of phosphate efflux pathways in rat liver mitochondria. The Biochemical Journal. 212: 279-88. PMID 6882372 DOI: 10.1042/Bj2120279  0.324
1983 Wehrle JP, Pedersen PL. Isolation and reconstitution of an N-ethylmaleimide-sensitive phosphate transport protein from rat liver mitochondria. Archives of Biochemistry and Biophysics. 223: 477-483. PMID 6305281 DOI: 10.1016/0003-9861(83)90612-4  0.417
1983 Amzel LM, Pedersen PL. Proton atpases: structure and mechanism Annual Review of Biochemistry. 52: 801-824. PMID 6225377 DOI: 10.1146/Annurev.Bi.52.070183.004101  0.6
1982 Amzel LM, McKinney M, Narayanan P, Pedersen PL. Structure of the mitochondrial F1 ATPase at 9-Å resolution Proceedings of the National Academy of Sciences of the United States of America. 79: 5852-5856. PMID 6225115 DOI: 10.1073/Pnas.79.19.5852  0.647
1982 Amzel LM, Narayanan P, Pedersen PL, Sygusch J. The three-dimensional structure of F1-ATPases Annals of the New York Academy of Sciences. 21-27. PMID 6220637 DOI: 10.1111/J.1749-6632.1982.Tb25729.X  0.604
1982 Cintron NM, Hullihen J, Schwerzmann K, Pedersen PL. Proton-adenosinetriphosphatase complex of rat liver mitochondria: effect of its inhibitory peptide on adenosine 5'-triphosphate hydrolytic and functional activities of the enzyme. Biochemistry. 21: 1878-1885. PMID 6211190 DOI: 10.1021/Bi00537A027  0.373
1981 Wehrle JP, Pedersen PL. Phosphate transport in rat liver mitochondria: Location of sulfhydryl groups essential for transport activities Journal of Bioenergetics and Biomembranes. 13: 285-294. PMID 7334021 DOI: 10.1007/Bf00743206  0.374
1981 Schwerzmann K, Pedersen PL. Proton--adenosinetriphosphatase complex of rat liver mitochondria: effect of energy state on its interaction with the adenosinetriphosphatase inhibitory peptide. Biochemistry. 20: 6305-6311. PMID 6458327 DOI: 10.1021/Bi00525A004  0.307
1981 Amzel LM, Narayanan P, Pedersen PL. Structure of mitochondrial F1-ATPase to 9 Å resolution Acta Crystallographica Section a Foundations of Crystallography. 37: C39-C39. DOI: 10.1107/S0108767381098437  0.584
1981 Pedersen P, Hullihen J, Wehrle J. Proton adenosine triphosphatase complex of rat liver. The effect of trypsin on the F1 and F0 moieties of the enzyme. Journal of Biological Chemistry. 256: 1362-1369. DOI: 10.1016/s0021-9258(19)69973-4  0.351
1980 Bustamante E, Pedersen PL. Mitochondrial hexokinase of rat hepatoma cells in culture: solubilization and kinetic properties. Biochemistry. 19: 4972-4977. PMID 6779859 DOI: 10.1021/Bi00563A006  0.461
1980 Pedersen PL, Amzel LM, Cintrón N, Soper JW, Hullihen J, Wehrle J. The ATP synthesizing system of liver mitochondria Advances in Experimental Medicine and Biology. 132: 317-344. PMID 6252767 DOI: 10.1007/978-1-4757-1419-7_33  0.58
1979 Coty WA, Wehrle JP, Pedersen PL. [29] Measurement of phosphate transport in mitochondria and in inverted inner membrane vesicles of rat liver Methods in Enzymology. 56: 353-359. PMID 459871 DOI: 10.1016/0076-6879(79)56032-7  0.374
1979 Pedersen PL, Catterall WA. The use of thin-layer chromatography on poly(ethyleneimine) cellulose to facilitate assays of ATP-ADP exchange, ATP-Pi exchange, adenylate kinase, and nucleoside diphosphokinase activity. Methods in Enzymology. 55: 283-9. PMID 222998 DOI: 10.1016/0076-6879(79)55032-0  0.369
1979 Kaschnitz RM, Hatefi Y, Pedersen PL, Morris HP. [9] Isolation of mitochondria from morris hepatomas Methods in Enzymology. 55: 79-88. PMID 156860 DOI: 10.1016/0076-6879(79)55011-3  0.343
1979 Pedersen PL, Hullihen J. [79] Resolution and reconstitution of ATP synthesis and ATP-dependent functions of liver mitochondria Methods in Enzymology. 55: 736-741. PMID 156857 DOI: 10.1016/0076-6879(79)55081-2  0.37
1979 Cintrón NM, Pedersen PL. [52] Purification of an ATPase inhibitor peptide fraction from rat liver mitochondria Methods in Enzymology. 55: 408-414. PMID 156850 DOI: 10.1016/0076-6879(79)55054-X  0.428
1979 Amzel LM, Pedersen PL. [39] Crystallization of F1 ATPase from rat liver mitochondria Methods in Enzymology. 55: 333-337. PMID 156840 DOI: 10.1016/0076-6879(79)55041-1  0.559
1979 Soper JW, Pedersen PL. [38] Isolation of an oligomycin-sensitive ATPase complex from rat liver mitochondria Methods in Enzymology. 55: 328-333. PMID 156839 DOI: 10.1016/0076-6879(79)55040-X  0.471
1979 Catterall WA, Pedersen PL, Lambeth DO, Lardy HA. Purification of F1 ATPase from rat liver mitochondria. Methods in Enzymology. 55: 320-8. PMID 156838 DOI: 10.1016/0076-6879(79)55039-3  0.513
1978 Bustamente E, Morris HP, Pedersen PL. Hexokinase: the direct link between mitochondrial and glycolytic reactions in rapidly growing cancer cells. Advances in Experimental Medicine and Biology. 92: 363-380. PMID 205103 DOI: 10.1007/978-1-4615-8852-8_15  0.427
1978 Pedersen PL, Greenawalt JW, Reynafarje B, Hullihen J, Decker GL, Soper JW, Bustamente E. Preparation and characterization of mitochondria and submitochondrial particles of rat liver and liver-derived tissues. Methods in Cell Biology. 20: 411-81. PMID 151184 DOI: 10.1016/S0091-679X(08)62030-0  0.372
1978 Pedersen P, Hullihen J. Adenosine triphosphatase of rat liver mitochondria. Capacity of the homogeneous F1 component of the enzyme to restore ATP synthesis in urea-treated membranes. Journal of Biological Chemistry. 253: 2176-2183. DOI: 10.1016/s0021-9258(17)38056-0  0.388
1977 Bustamante E, Soper JW, Pedersen PL. A high-yield preparative method for isolation of rat liver mitochondria. Analytical Biochemistry. 80: 401-408. PMID 889080 DOI: 10.1016/0003-2697(77)90661-3  0.388
1977 Bustamante E, Pedersen PL. High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase Proceedings of the National Academy of Sciences of the United States of America. 74: 3735-3739. PMID 198801 DOI: 10.1073/Pnas.74.9.3735  0.386
1977 Woods TA, Decker GL, Pedersen PL. Antihyperlipidemic drugs-In vitro effect on the function and structure of rat liver mitochondria Journal of Molecular and Cellular Cardiology. 9. PMID 144192 DOI: 10.1016/S0022-2828(77)80058-8  0.367
1976 Pedersen PL. Adenosine triphosphatase from rat liver mitochondria - evidence for a mercurial-sensitive site for the activating anion bicarbonate. Biochemical and Biophysical Research Communications. 71: 1182-1188. PMID 135559 DOI: 10.1016/0006-291X(76)90778-6  0.437
1976 Soper JW, Pedersen PL. Adenosine triphosphatase of rat liver mitochondria: detergent solubilization of an oligomycin- and dicyclohexylcarbodiimide-sensitive form of the enzyme Biochemistry. 15: 2682-2690. PMID 132962 DOI: 10.1021/Bi00657A031  0.412
1975 Pedersen PL. Interaction of homogeneous mitochondrial ATPase from rat liver with adenine nucleotides and inorganic phosphate. Journal of Supramolecular Structure. 3: 222-230. PMID 127085 DOI: 10.1002/Jss.400030304  0.475
1975 Pedersen PL. Adenosine triphosphatase from rat liver mitochondria: separate sites involved in ATP hydrolysis and in the reversible, high affinity binding of ADP. Biochemical and Biophysical Research Communications. 64: 610-616. PMID 125085 DOI: 10.1016/0006-291X(75)90365-4  0.444
1975 Coty WA, Pedersen PL. Phosphate transport in rat liver mitochondria. Kinetics, inhibitor sensitivity, energy requirements, and labeled components. Molecular and Cellular Biochemistry. 9: 109-124. PMID 609 DOI: 10.1007/Bf01732202  0.364
1975 Pedersen PL. Mitochondrial adenosine triphosphatase Journal of Bioenergetics and Biomembranes. 6: 243-275. DOI: 10.1007/Bf01648966  0.303
1973 Bustamante E, Pedersen PL. Tetradifon: an oligomycin-like inhibitor of energy-linked activities of rat liver mitochondria. Biochemical and Biophysical Research Communications. 51: 292-298. PMID 4266412 DOI: 10.1016/0006-291X(73)91255-2  0.427
1972 Pedersen PL, Catterall WA. Contribution of ATP synthesis from endogenous substrates to the oligomycin-sensitive ADP-ATP exchange activity of rat liver mitoplasts. Biochemical and Biophysical Research Communications. 45: 809-15. PMID 4256848 DOI: 10.1016/0006-291X(71)90489-X  0.458
1971 Pedersen PL, Eska T, Morris HP, Catterall WA. Deficiency of uncoupler-stimulated adenosine triphosphatase activity in tightly coupled hepatoma mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 68: 1079-82. PMID 4325001 DOI: 10.1073/Pnas.68.5.1079  0.451
1970 Chan TL, Greenawalt JW, Pedersen PL. Biochemical and ultrastructural properties of a mitochondrial inner membrane fraction deficient in outer membrane and matrix activities. The Journal of Cell Biology. 45: 291-305. PMID 4254678 DOI: 10.1083/Jcb.45.2.291  0.369
1970 Catterall WA, Pedersen PL. Effects of phosphotungstic acid and silicotungstic acid on respiration and integrity of rat liver mitochondria. Biochemical and Biophysical Research Communications. 38: 400-5. PMID 4192036 DOI: 10.1016/0006-291X(70)90727-8  0.361
1968 Schnaitman CA, Pedersen PL. Localization of oligomycin-sensitive ADP-ATP exchange activity in rat liver mitochondria. Biochemical and Biophysical Research Communications. 30: 428-433. PMID 4230014 DOI: 10.1016/0006-291X(68)90762-6  0.445
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