| Year |
Citation |
Score |
| 2023 |
Usai R, Kaluka D, Cai S, Sem DS, Kincaid JR. Solution phase refinement of active site structure using 2D NMR and judiciously C-labeled cytochrome P450. Journal of Inorganic Biochemistry. 241: 112126. PMID 36682280 DOI: 10.1016/j.jinorgbio.2023.112126 |
0.305 |
|
| 2021 |
Fleischer AW, Schalk JC, Wetzel EA, Hanson AM, Sem DS, Donaldson WA, Frick KM. Chronic oral administration of a novel estrogen receptor beta agonist enhances memory and alleviates drug-induced vasodilation in young ovariectomized mice. Hormones and Behavior. 104948. PMID 33571507 DOI: 10.1016/j.yhbeh.2021.104948 |
0.516 |
|
| 2019 |
Hanson AM, Perera IS, Kim J, Sweeney N, Imhoff A, Wargolet AJ, Hart RMV, Mackinnon AC, Frick KM, Sem DS, Donaldson WA. Potent and Selective Estrogen Receptor-Beta Agonists Which Enhance Memory Consolidation in an Ovariectomized Mouse Model Proceedings. 22: 73. DOI: 10.3390/PROCEEDINGS2019022073 |
0.536 |
|
| 2018 |
Hanson AM, Perera KLIS, Kim J, Pandey RK, Sweeney N, Lu X, Imhoff A, Mackinnon AC, Wargolet AJ, Van Hart RM, Frick KM, Donaldson WA, Sem DS. A-C Estrogens as Potent and Selective Estrogen Receptor-beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-estrogen Conditions. Journal of Medicinal Chemistry. PMID 29741891 DOI: 10.1021/Acs.Jmedchem.7B01601 |
0.574 |
|
| 2017 |
Hillard CJ, Huang H, Vogt CD, Rodrigues BE, Neumann TS, Sem DS, Schroeder F, Cunningham CW. Endocannabinoid Transport Proteins: Discovery of Tools to Study Sterol Carrier Protein-2. Methods in Enzymology. 593: 99-121. PMID 28750817 DOI: 10.1016/Bs.Mie.2017.06.017 |
0.345 |
|
| 2016 |
Talipov MR, Nayak J, Lepley M, Bongard RD, Sem DS, Ramchandran R, Rathore R. Critical Role of the Secondary Binding Pocket in Modulating Enzymatic Activity of DUSP5 towards Phosphorylated ERKs. Biochemistry. PMID 27739308 DOI: 10.1021/Acs.Biochem.6B00498 |
0.399 |
|
| 2015 |
Pradeep P, Struble C, Neumann T, Sem DS, Merrill SJ. A Novel Scoring Based Distributed Protein Docking Application to Improve Enrichment. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 12: 1464-9. PMID 26671816 DOI: 10.1109/Tcbb.2015.2401020 |
0.353 |
|
| 2014 |
Liedhegner ES, Vogt CD, Sem DS, Cunningham CW, Hillard CJ. Sterol carrier protein-2: binding protein for endocannabinoids. Molecular Neurobiology. 50: 149-58. PMID 24510313 DOI: 10.1007/s12035-014-8651-7 |
0.363 |
|
| 2014 |
McCullough C, Neumann TS, Gone JR, He Z, Herrild C, Wondergem Nee Lukesh J, Pandey RK, Donaldson WA, Sem DS. Probing the human estrogen receptor-α binding requirements for phenolic mono- and di-hydroxyl compounds: a combined synthesis, binding and docking study. Bioorganic & Medicinal Chemistry. 22: 303-10. PMID 24315190 DOI: 10.1016/J.Bmc.2013.11.024 |
0.407 |
|
| 2013 |
McCullough C, Pullela PK, Im SC, Waskell L, Sem D. The synthesis, characterization, and application of 13C-methyl isocyanide as an NMR probe of heme protein active sites Methods in Molecular Biology. 987: 51-59. PMID 23475666 DOI: 10.1007/978-1-62703-321-3_4 |
0.461 |
|
| 2013 |
Boonsri P, Neumann TS, Olson AL, Cai S, Herdendorf TJ, Miziorko HM, Hannongbua S, Sem DS. Molecular docking and NMR binding studies to identify novel inhibitors of human phosphomevalonate kinase. Biochemical and Biophysical Research Communications. 430: 313-9. PMID 23146631 DOI: 10.1016/J.Bbrc.2012.10.130 |
0.361 |
|
| 2012 |
Hoffmann BR, El-Mansy MF, Sem DS, Greene AS. Chemical proteomics-based analysis of off-target binding profiles for rosiglitazone and pioglitazone: clues for assessing potential for cardiotoxicity. Journal of Medicinal Chemistry. 55: 8260-71. PMID 22970990 DOI: 10.1021/Jm301204R |
0.326 |
|
| 2012 |
Ge X, Sem DS. Affinity-based profiling of dehydrogenase subproteomes. Methods in Molecular Biology (Clifton, N.J.). 803: 157-65. PMID 22065224 DOI: 10.1007/978-1-61779-364-6_11 |
0.535 |
|
| 2012 |
Ge X, Sem DS. A chemical proteomic probe for detecting dehydrogenases: catechol rhodanine. Methods in Molecular Biology (Clifton, N.J.). 803: 55-64. PMID 22065218 DOI: 10.1007/978-1-61779-364-6_5 |
0.643 |
|
| 2010 |
Olson AL, Cai S, Herdendorf TJ, Miziorko HM, Sem DS. NMR dynamics investigation of ligand-induced changes of main and side-chain arginine N-H's in human phosphomevalonate kinase Journal of the American Chemical Society. 132: 2102-2103. PMID 20112895 DOI: 10.1021/Ja906244J |
0.372 |
|
| 2009 |
McCullough CR, Pullela PK, Im SC, Waskell L, Sem DS. 13C-Methyl isocyanide as an NMR probe for cytochrome P450 active sites Journal of Biomolecular Nmr. 43: 171-178. PMID 19199046 DOI: 10.1007/S10858-009-9300-8 |
0.429 |
|
| 2009 |
Olson AL, Yao H, Herdendorf TJ, Miziorko HM, Hannongbua S, Saparpakorn P, Cai S, Sem DS. Substrate induced structural and dynamics changes in human phosphomevalonate kinase and implications for mechanism Proteins: Structure, Function and Bioinformatics. 75: 127-138. PMID 18798562 DOI: 10.1002/Prot.22228 |
0.623 |
|
| 2008 |
Ge X, Olson A, Cai S, Sem DS. Binding synergy and cooperativity in dihydrodipicolinate reductase: implications for mechanism and the design of biligand inhibitors. Biochemistry. 47: 9966-80. PMID 18710263 DOI: 10.1021/Bi8007005 |
0.67 |
|
| 2008 |
Ge X, Wakim B, Sem DS. Chemical proteomics-based drug design: target and antitarget fishing with a catechol-rhodanine privileged scaffold for NAD(P)(H) binding proteins. Journal of Medicinal Chemistry. 51: 4571-80. PMID 18616236 DOI: 10.1021/Jm8002284 |
0.585 |
|
| 2008 |
Yao H, Stuart RA, Cai S, Sem DS. Structural characterization of the transmembrane domain from subunit e of yeast F1Fo-ATP synthase: a helical GXXXG motif located just under the micelle surface. Biochemistry. 47: 1910-7. PMID 18220416 DOI: 10.1021/Bi7015475 |
0.53 |
|
| 2008 |
Plesniak LA, Botsch K, Leibrand M, Kelly M, Sem D, Adams JA, Jennings P. Transferred NOE and saturation transfer difference NMR studies of novobiocin binding to EnvZ suggest binding mode similar to DNA gyrase. Chemical Biology & Drug Design. 71: 28-35. PMID 18093089 DOI: 10.1111/J.1747-0285.2007.00607.X |
0.443 |
|
| 2007 |
Ge X, Sem DS. Affinity-based chemical proteomic probe for dehydrogenases: fluorescence and visible binding assays in gels. Analytical Biochemistry. 370: 171-9. PMID 17870049 DOI: 10.1016/J.Ab.2007.08.010 |
0.583 |
|
| 2007 |
Costache AD, Trawick D, Bohl D, Sem DS. AmineDB: large scale docking of amines with CYP2D6 and scoring for druglike properties--towards defining the scope of the chemical defense against foreign amines in humans. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 37: 221-45. PMID 17624022 DOI: 10.1080/00498250601089162 |
0.749 |
|
| 2007 |
Yao H, McCullough CR, Costache AD, Pullela PK, Sem DS. Structural evidence for a functionally relevant second camphor binding site in P450cam: model for substrate entry into a P450 active site. Proteins. 69: 125-38. PMID 17598143 DOI: 10.1002/Prot.21508 |
0.725 |
|
| 2006 |
Bazeley PS, Prithivi S, Struble CA, Povinelli RJ, Sem DS. Synergistic use of compound properties and docking scores in neural network modeling of CYP2D6 binding: predicting affinity and conformational sampling. Journal of Chemical Information and Modeling. 46: 2698-708. PMID 17125210 DOI: 10.1021/Ci600267K |
0.379 |
|
| 2005 |
Costache AD, Pullela PK, Kasha P, Tomasiewicz H, Sem DS. Homology-modeled ligand-binding domains of zebrafish estrogen receptors alpha, beta1, and beta2: from in silico to in vivo studies of estrogen interactions in Danio rerio as a model system. Molecular Endocrinology (Baltimore, Md.). 19: 2979-90. PMID 16081519 DOI: 10.1210/Me.2004-0435 |
0.742 |
|
| 2005 |
Yao H, Sem DS. Cofactor fingerprinting with STD NMR to characterize proteins of unknown function: identification of a rare cCMP cofactor preference. Febs Letters. 579: 661-6. PMID 15670825 DOI: 10.1016/J.Febslet.2004.11.110 |
0.591 |
|
| 2004 |
Yao H, Costache AD, Sem DS. Chemical proteomic tool for ligand mapping of CYP antitargets: an NMR-compatible 3D QSAR descriptor in the Heme-Based Coordinate System. Journal of Chemical Information and Computer Sciences. 44: 1456-65. PMID 15272854 DOI: 10.1021/Ci034208Q |
0.724 |
|
| 2004 |
Sem DS, Bertolaet B, Baker B, Chang E, Costache AD, Coutts S, Dong Q, Hansen M, Hong V, Huang X, Jack RM, Kho R, Lang H, Ma CT, Meininger D, et al. Systems-based design of bi-ligand inhibitors of oxidoreductases: filling the chemical proteomic toolbox. Chemistry & Biology. 11: 185-94. PMID 15123280 DOI: 10.1016/J.Chembiol.2004.02.012 |
0.748 |
|
| 2002 |
Plesniak L, Horiuchi Y, Sem D, Meinenger D, Stiles L, Shaffer J, Jennings PA, Adams JA. Probing the nucleotide binding domain of the osmoregulator EnvZ using fluorescent nucleotide derivatives. Biochemistry. 41: 13876-82. PMID 12437344 DOI: 10.1021/Bi020331J |
0.506 |
|
| 2002 |
Pellecchia M, Sem DS, Wüthrich K. NMR in drug discovery Nature Reviews Drug Discovery. 1: 211-219. PMID 12120505 |
0.302 |
|
| 1998 |
Holmbeck SM, Foster MP, Casimiro DR, Sem DS, Dyson HJ, Wright PE. High-resolution solution structure of the retinoid X receptor DNA-binding domain. Journal of Molecular Biology. 281: 271-84. PMID 9698548 DOI: 10.1006/Jmbi.1998.1908 |
0.31 |
|
| 1997 |
Sem DS, Casimiro DR, Kliewer SA, Provencal J, Evans RM, Wright PE. NMR spectroscopic studies of the DNA-binding domain of the monomer-binding nuclear orphan receptor, human estrogen related receptor-2. The carboxyl-terminal extension to the zinc-finger region is unstructured in the free form of the protein. The Journal of Biological Chemistry. 272: 18038-43. PMID 9218433 DOI: 10.1074/Jbc.272.29.18038 |
0.327 |
|
| 1994 |
Lee MS, Sem DS, Kliewer SA, Provencal J, Evans RM, Wright PE. NMR assignments and secondary structure of the retinoid X receptor alpha DNA-binding domain. Evidence for the novel C-terminal helix. European Journal of Biochemistry. 224: 639-50. PMID 7925381 DOI: 10.1111/J.1432-1033.1994.00639.X |
0.301 |
|
| 1993 |
Sem DS, Kasper CB. Enzyme-substrate binding interactions of NADPH-cytochrome P-450 oxidoreductase characterized with pH and alternate substrate/inhibitor studies. Biochemistry. 32: 11539-47. PMID 8218221 DOI: 10.1021/bi00094a010 |
0.311 |
|
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