Junhao Mao, Ph.D. - Publications

Affiliations: 
2002 University of Rochester, Rochester, NY 
Area:
Pharmacology, Molecular Biology

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Qi S, Zhong Z, Zhu Y, Wang Y, Ma M, Wang Y, Liu X, Jin R, Jiao Z, Zhu R, Sha Z, Dang K, Liu Y, Lim DS, Mao J, et al. Two Hippo signaling modules orchestrate liver size and tumorigenesis. The Embo Journal. e112126. PMID 36919851 DOI: 10.15252/embj.2022112126  0.314
2022 Cotton JL, Dang K, Hu L, Sun Y, Singh A, Rajurkar MS, Li Q, Wu X, Mao J. PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis. Cell Reports. 40: 111125. PMID 35858546 DOI: 10.1016/j.celrep.2022.111125  0.386
2020 Cheung P, Xiol J, Dill MT, Yuan WC, Panero R, Roper J, Osorio FG, Maglic D, Li Q, Gurung B, Calogero RA, Yilmaz ÖH, Mao J, Camargo FD. Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer. Cell Stem Cell. PMID 32730753 DOI: 10.1016/J.Stem.2020.07.003  0.488
2020 Eder N, Roncaroli F, Dolmart MC, Horswell S, Andreiuolo F, Flynn HR, Lopes AT, Claxton S, Kilday JP, Collinson L, Mao JH, Pietsch T, Thompson B, Snijders AP, Ultanir SK. YAP1/TAZ drives ependymoma-like tumour formation in mice. Nature Communications. 11: 2380. PMID 32404936 DOI: 10.1038/S41467-020-16167-Y  0.386
2020 Li Q, Sun Y, Jarugumilli GK, Liu S, Dang K, Cotton JL, Xiol J, Chan PY, DeRan M, Ma L, Li R, Zhu LJ, Li JH, Leiter AB, Ip YT, ... ... Mao J, et al. Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription. Cell Stem Cell. PMID 32259481 DOI: 10.1016/J.Stem.2020.03.002  0.506
2020 Cotton JL, Dang K, Li Q, Johnson RL, Ip YT, Wu X, Mao J. Abstract PR03: YAP/TAZ requirement in mesenchyme-originated intestinal hamartomatous polyposis Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-Pr03  0.399
2020 Eder N, Dolmart M, Claxton S, Cotton J, Mao J, Snijders B, Roncaroli F, Thompson B, Ultanir S. Abstract A01: YAP1 drives ependymoma-like tumor formation in the brain Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-A01  0.398
2019 Li H, Li Q, Dang K, Ma S, Cotton JL, Yang S, Zhu LJ, Deng AC, Ip YT, Johnson RL, Wu X, Punzo C, Mao J. YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression. Cell Reports. 29: 3200-3211.e4. PMID 31801083 DOI: 10.1016/J.Celrep.2019.03.021  0.449
2019 Li Q, Nirala NK, Chen HJ, Nie Y, Wang W, Zhang B, Czech MP, Wang Q, Xu L, Mao J, Ip YT. The Misshapen subfamily of Ste20 kinases regulate proliferation in the aging mammalian intestinal epithelium. Journal of Cellular Physiology. PMID 31042012 DOI: 10.1002/Jcp.28756  0.403
2018 Vincent-Mistiaen Z, Elbediwy A, Vanyai H, Cotton J, Stamp G, Nye E, Spencer-Dene B, Thomas GJ, Mao J, Thompson B. YAP drives cutaneous squamous cell carcinoma formation and progression. Elife. 7. PMID 30231971 DOI: 10.7554/Elife.33304  0.371
2018 Li Q, Nirala NK, Nie Y, Chen HJ, Ostroff G, Mao J, Wang Q, Xu L, Ip YT. Ingestion of Food Particles Regulates the Mechanosensing Misshapen-Yorkie Pathway in Drosophila Intestinal Growth. Developmental Cell. PMID 29754801 DOI: 10.1016/J.Devcel.2018.04.014  0.364
2017 Cotton JL, Li Q, Ma L, Park JS, Wang J, Ou J, Zhu LJ, Ip YT, Johnson RL, Mao J. YAP/TAZ and Hedgehog Coordinate Growth and Patterning in Gastrointestinal Mesenchyme. Developmental Cell. PMID 28943241 DOI: 10.1016/J.Devcel.2017.08.019  0.459
2017 Rajurkar M, Dang K, Fernandez-Barrena MG, Liu X, Fernandez-Zapico ME, Lewis BC, Mao J. IKBKE Is Required during KRAS-Induced Pancreatic Tumorigenesis. Cancer Research. PMID 28069799 DOI: 10.1158/0008-5472.Can-15-1684  0.451
2016 Tang CM, Lee TE, Syed SA, Burgoyne AM, Leonard SY, Gao F, Chan JC, Shi E, Chmielecki J, Morosini D, Wang K, Ross JS, Kendrick ML, Bardsley MR, De Siena M, ... Mao J, et al. Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression. Oncotarget. PMID 27793025 DOI: 10.18632/Oncotarget.12909  0.461
2016 Liu X, Li H, Rajurkar M, Li Q, Cotton JL, Ou J, Zhu LJ, Goel HL, Mercurio AM, Park JS, Davis RJ, Mao J. Tead and AP1 Coordinate Transcription and Motility. Cell Reports. PMID 26832411 DOI: 10.1016/J.Celrep.2015.12.104  0.44
2016 Liu X, Li H, Rajurkar M, Cotton J, Mercurio A, Davis R, Mao J. Abstract B07: Tead and AP1 coordinate transcription and motility in cancer cells Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-B07  0.407
2016 Cotton JL, Li Q, Ma L, Ip T, Johnson R, Mao J. Abstract B06: Complex requirement of YAP and TAZ in gastrointestinal development and tumorigenesis Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-B06  0.48
2016 Rajurkar M, Fernandez-Zapico M, Lewis B, Mao J. Abstract B04: IKBKE integrates Gli and mTOR-AKT activation during Kras-induced pancreatic tumorigenesis Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-B04  0.458
2015 Hettmer S, Lin MM, Tchessalova D, Tortorici SJ, Castiglioni A, Desai T, Mao J, McMahon AP, Wagers AJ. Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity. Experimental Cell Research. PMID 26460176 DOI: 10.1016/J.Yexcr.2015.10.008  0.361
2015 Chang C, Goel HL, Gao H, Pursell B, Shultz LD, Greiner DL, Ingerpuu S, Patarroyo M, Cao S, Lim E, Mao J, McKee KK, Yurchenco PD, Mercurio AM. A laminin 511 matrix is regulated by TAZ and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells. Genes & Development. 29: 1-6. PMID 25561492 DOI: 10.1101/Gad.253682.114  0.333
2015 Rajurkar M, Mao J. Abstract A91: IKBKE signaling in pancreatic tumorigenesis Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A91  0.469
2014 Junker JP, Peterson KA, Nishi Y, Mao J, McMahon AP, van Oudenaarden A. A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning. Developmental Cell. 31: 448-60. PMID 25458012 DOI: 10.1016/J.Devcel.2014.10.017  0.427
2014 Li Q, Li S, Mana-Capelli S, Roth Flach RJ, Danai LV, Amcheslavsky A, Nie Y, Kaneko S, Yao X, Chen X, Cotton JL, Mao J, McCollum D, Jiang J, Czech MP, et al. The conserved misshapen-warts-Yorkie pathway acts in enteroblasts to regulate intestinal stem cells in Drosophila. Developmental Cell. 31: 291-304. PMID 25453828 DOI: 10.1016/J.Devcel.2014.09.012  0.479
2014 Cotton J, Huang H, Rajurkar M, Mao J. Abstract 98: A novel mouse model for intestinal serrated polyposis Cancer Research. 74: 98-98. DOI: 10.1158/1538-7445.Am2014-98  0.457
2013 Hettmer S, Teot LA, van Hummelen P, MacConaill L, Bronson RT, Dall'Osso C, Mao J, McMahon AP, Gruber PJ, Grier HE, Rodriguez-Galindo C, Fletcher CD, Wagers AJ. Mutations in Hedgehog pathway genes in fetal rhabdomyomas. The Journal of Pathology. 231: 44-52. PMID 23780909 DOI: 10.1002/Path.4229  0.408
2013 Wang J, Park JS, Wei Y, Rajurkar M, Cotton JL, Fan Q, Lewis BC, Ji H, Mao J. TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPα function. Molecular Cell. 51: 211-25. PMID 23769673 DOI: 10.1016/J.Molcel.2013.05.013  0.419
2013 Huang H, Cotton JL, Wang Y, Rajurkar M, Zhu LJ, Lewis BC, Mao J. Specific requirement of Gli transcription factors in Hedgehog-mediated intestinal development. The Journal of Biological Chemistry. 288: 17589-96. PMID 23645682 DOI: 10.1074/Jbc.M113.467498  0.475
2013 Goel HL, Pursell B, Chang C, Shaw LM, Mao J, Simin K, Kumar P, Vander Kooi CW, Shultz LD, Greiner DL, Norum JH, Toftgard R, Kuperwasser C, Mercurio AM. GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation. Embo Molecular Medicine. 5: 488-508. PMID 23436775 DOI: 10.1002/Emmm.201202078  0.44
2012 Rajurkar M, De Jesus-Monge WE, Driscoll DR, Appleman VA, Huang H, Cotton JL, Klimstra DS, Zhu LJ, Simin K, Xu L, McMahon AP, Lewis BC, Mao J. The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 109: E1038-47. PMID 22493246 DOI: 10.1073/Pnas.1114168109  0.457
2012 Rajurkar M, Jesus-Monge WED, Driscoll D, Cotton JL, Lewis BC, Mao J. Abstract LB-105: Gli-IKBKE interactions in pancreatic tumorigenesis Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-105  0.47
2011 Kim TH, Kim BM, Mao J, Rowan S, Shivdasani RA. Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme. Development (Cambridge, England). 138: 3225-33. PMID 21750033 DOI: 10.1242/Dev.066233  0.486
2011 Kaneko S, Chen X, Lu P, Yao X, Wright TG, Rajurkar M, Kariya K, Mao J, Ip YT, Xu L. Smad inhibition by the Ste20 kinase Misshapen. Proceedings of the National Academy of Sciences of the United States of America. 108: 11127-32. PMID 21690388 DOI: 10.1073/Pnas.1104128108  0.374
2011 Rajurkar M, Jesus-Monge WED, Lewis BC, Mao J. The Requirement of GLI Transcriptional Activity in KRAS-Induced Pancreatic Neoplasia Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)60215-1  0.465
2011 Jesus-Monge WED, Rajurkar M, Mao J, Lewis BC. GLI Activation is Required for Pancreatic Tumor Formation In Vivo Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)60134-0  0.342
2010 Mao J, Kim BM, Rajurkar M, Shivdasani RA, McMahon AP. Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract. Development (Cambridge, England). 137: 1721-9. PMID 20430747 DOI: 10.1242/Dev.044586  0.457
2009 Hofmann I, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Cornejo MG, Okabe R, Armstrong SA, Ghilardi N, Gould S, de Sauvage FJ, McMahon AP, et al. Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis. Cell Stem Cell. 4: 559-67. PMID 19497284 DOI: 10.1016/J.Stem.2009.03.016  0.438
2009 Mao J, McGlinn E, Huang P, Tabin CJ, McMahon AP. Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb. Developmental Cell. 16: 600-6. PMID 19386268 DOI: 10.1016/J.Devcel.2009.02.005  0.411
2008 Schüller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL. Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell. 14: 123-34. PMID 18691547 DOI: 10.1016/J.Ccr.2008.07.005  0.415
2008 Zhang IH, Stover EH, Cullen DE, Mao J, Morgan KJ, Lee BH, Kharas MG, Miller PG, Okabe R, Armstrong SA, Ghilardi N, Gould S, deSauvage FJ, McMahon AP, Gilliland DG. Hedgehog Signaling Is Dispensable for Adult Murine Hematopoiesis and Leukemogenesis. Blood. 112: 1391-1391. DOI: 10.1182/blood.v112.11.1391.1391  0.373
2007 Kim BM, Miletich I, Mao J, McMahon AP, Sharpe PA, Shivdasani RA. Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen. Development (Cambridge, England). 134: 3603-13. PMID 17855428 DOI: 10.1242/Dev.009308  0.442
2007 Kim BM, Mao J, Taketo MM, Shivdasani RA. Phases of canonical Wnt signaling during the development of mouse intestinal epithelium. Gastroenterology. 133: 529-38. PMID 17681174 DOI: 10.1053/J.Gastro.2007.04.072  0.43
2007 McGlinn E, Mao J, Nissim S, McMahon A, Tabin C. Novel molecular mechanisms regulating Shh expression and limb patterning The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A199-C  0.321
2006 Mao J, Ligon KL, Rakhlin EY, Thayer SP, Bronson RT, Rowitch D, McMahon AP. A novel somatic mouse model to survey tumorigenic potential applied to the Hedgehog pathway. Cancer Research. 66: 10171-8. PMID 17047082 DOI: 10.1158/0008-5472.Can-06-0657  0.399
2005 Mao J, Barrow J, McMahon J, Vaughan J, McMahon AP. An ES cell system for rapid, spatial and temporal analysis of gene function in vitro and in vivo. Nucleic Acids Research. 33: e155. PMID 16221970 DOI: 10.1093/Nar/Gni146  0.442
2004 Zhang Y, Wang Y, Li X, Zhang J, Mao J, Li Z, Zheng J, Li L, Harris S, Wu D. The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd. Molecular and Cellular Biology. 24: 4677-84. PMID 15143163 DOI: 10.1128/Mcb.24.11.4677-4684.2004  0.39
2004 Jeong J, Mao J, Tenzen T, Kottmann AH, McMahon AP. Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. Genes & Development. 18: 937-51. PMID 15107405 DOI: 10.1101/Gad.1190304  0.442
2003 Weaver C, Farr GH, Pan W, Rowning BA, Wang J, Mao J, Wu D, Li L, Larabell CA, Kimelman D. GBP binds kinesin light chain and translocates during cortical rotation in Xenopus eggs. Development (Cambridge, England). 130: 5425-36. PMID 14507779 DOI: 10.1242/Dev.00737  0.316
2002 Mao J, Maye P, Kogerman P, Tejedor FJ, Toftgard R, Xie W, Wu G, Wu D. Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1. The Journal of Biological Chemistry. 277: 35156-61. PMID 12138125 DOI: 10.1074/Jbc.M206743200  0.486
2002 Li L, Mao J, Sun L, Liu W, Wu D. Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled. The Journal of Biological Chemistry. 277: 5977-81. PMID 11742004 DOI: 10.1074/Jbc.M111131200  0.432
2002 Mao J, Wu D. Functional interaction of G alpha 13 with p115RhoGEF determined with transcriptional reporter system. Methods in Enzymology. 345: 404-10. PMID 11665624 DOI: 10.1016/S0076-6879(02)45033-1  0.399
2001 Mao J, Wang J, Liu B, Pan W, Farr GH, Flynn C, Yuan H, Takada S, Kimelman D, Li L, Wu D. Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Molecular Cell. 7: 801-9. PMID 11336703 DOI: 10.1016/S1097-2765(01)00224-6  0.454
2000 Wong HC, Mao J, Nguyen JT, Srinivas S, Zhang W, Liu B, Li L, Wu D, Zheng J. Structural basis of the recognition of the Dishevelled DEP domain in the Wnt signaling pathway Nature Structural Biology. 7: 1178-1184. PMID 11101902 DOI: 10.1038/82047  0.39
1999 Yuan H, Mao J, Li L, Wu D. Suppression of glycogen synthase kinase activity is not sufficient for leukemia enhancer factor-1 activation. The Journal of Biological Chemistry. 274: 30419-23. PMID 10521419 DOI: 10.1074/Jbc.274.43.30419  0.432
1999 Li L, Yuan H, Weaver CD, Mao J, Farr GH, Sussman DJ, Jonkers J, Kimelman D, Wu D. Axin and Frat1 interact with Dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1 Embo Journal. 18: 4233-4240. PMID 10428961 DOI: 10.1093/Emboj/18.15.4233  0.453
1999 Li L, Yuan H, Xie W, Mao J, Caruso AM, McMahon A, Sussman DJ, Wu D. Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cells. The Journal of Biological Chemistry. 274: 129-34. PMID 9867820 DOI: 10.1074/Jbc.274.1.129  0.494
1998 Mao J, Yuan H, Xie W, Wu D. Guanine nucleotide exchange factor GEF115 specifically mediates activation of Rho and serum response factor by the G protein alpha subunit Galpha13. Proceedings of the National Academy of Sciences of the United States of America. 95: 12973-6. PMID 9789025 DOI: 10.1073/Pnas.95.22.12973  0.399
1998 Mao J, Yuan H, Xie W, Simon MI, Wu D. Specific involvement of G proteins in regulation of serum response factor-mediated gene transcription by different receptors. The Journal of Biological Chemistry. 273: 27118-23. PMID 9765229 DOI: 10.1074/Jbc.273.42.27118  0.305
1998 Mao J, Xie W, Yuan H, Simon MI, Mano H, Wu D. Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Galpha12/13. The Embo Journal. 17: 5638-46. PMID 9755164 DOI: 10.1093/Emboj/17.19.5638  0.412
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