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Usha Ponnappan - Publications

Affiliations: 
Microbiology and Immunology University of Arkansas for Medical Sciences, United States 
Area:
Immunology, Cell Biology
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Chang J, Wang Y, Shao L, Laberge RM, Demaria M, Campisi J, Janakiraman K, Sharpless NE, Ding S, Feng W, Luo Y, Wang X, Aykin-Burns N, Krager K, Ponnappan U, et al. Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice. Nature Medicine. PMID 26657143 DOI: 10.1038/Nm.4010  0.307
2015 Cullen S, Ponnappan S, Ponnappan U. Redox-regulated pathway of tyrosine phosphorylation underlies NF-κB induction by an atypical pathway independent of the 26S proteasome. Biomolecules. 5: 95-112. PMID 25671697 DOI: 10.3390/biom5010095  0.699
2014 Pathak R, Shao L, Chafekar SM, Feng W, Ponnappan U, Fink LM, Zhou D, Hauer-Jensen M. IKKβ regulates endothelial thrombomodulin in a Klf2-dependent manner. Journal of Thrombosis and Haemostasis : Jth. 12: 1533-44. PMID 25039491 DOI: 10.1111/Jth.12664  0.496
2013 Ponnappan S, Palmieri M, Sullivan DH, Ponnappan U. Compensatory increase in USP14 activity accompanies impaired proteasomal proteolysis during aging. Mechanisms of Ageing and Development. 134: 53-9. PMID 23291607 DOI: 10.1016/J.Mad.2012.12.007  0.554
2012 Cané S, Ponnappan S, Ponnappan U. Altered regulation of CXCR4 expression during aging contributes to increased CXCL12-dependent chemotactic migration of CD4(+) T cells. Aging Cell. 11: 651-8. PMID 22568557 DOI: 10.1111/J.1474-9726.2012.00830.X  0.435
2012 Cane S, Ponnappan S, Ponnappan U. Impairment of non-muscle myosin IIA in human CD4+ T cells contributes to functional deficits in the elderly. Cellular & Molecular Immunology. 9: 86-96. PMID 21983869 DOI: 10.1038/Cmi.2011.41  0.44
2011 Ponnappan S, Ponnappan U. Aging and immune function: molecular mechanisms to interventions. Antioxidants & Redox Signaling. 14: 1551-85. PMID 20812785 DOI: 10.1089/Ars.2010.3228  0.386
2010 Cullen SJ, Ponnappan S, Ponnappan U. Proteasome inhibition up-regulates inflammatory gene transcription induced by an atypical pathway of NF-kappaB activation. Biochemical Pharmacology. 79: 706-14. PMID 19835847 DOI: 10.1016/J.Bcp.2009.10.006  0.692
2010 Tarasenko O, Scott A, Soderberg L, Ponnappan U, Alusta P. Killing of Bacillus spores is mediated by nitric oxide and nitric oxide synthase during glycoconjugate-enhanced phagocytosis. Glycoconjugate Journal. 27: 13-25. PMID 19548085 DOI: 10.1007/S10719-009-9248-7  0.371
2009 Cullen SJ, Ponnappan S, Ponnappan U. Catalytic activity of the proteasome fine-tunes Brg1-mediated chromatin remodeling to regulate the expression of inflammatory genes. Molecular Immunology. 47: 600-5. PMID 19800126 DOI: 10.1016/J.Molimm.2009.09.008  0.676
2007 Ponnappan S, Ovaa H, Ponnappan U. Lower expression of catalytic and structural subunits of the proteasome contributes to decreased proteolysis in peripheral blood T lymphocytes during aging. The International Journal of Biochemistry & Cell Biology. 39: 799-809. PMID 17317272 DOI: 10.1016/J.Biocel.2007.01.002  0.497
2007 Das R, Ponnappan S, Ponnappan U. Redox regulation of the proteasome in T lymphocytes during aging. Free Radical Biology & Medicine. 42: 541-51. PMID 17275686 DOI: 10.1016/J.Freeradbiomed.2006.11.020  0.689
2005 Ponnappan S, Cullen SJ, Ponnappan U. Constitutive degradation of IkappaBalpha in human T lymphocytes is mediated by calpain. Immunity & Ageing : I & A. 2: 15. PMID 16271147 DOI: 10.1186/1742-4933-2-15  0.695
2004 Soderberg LSF, Ponnappan U, Roy A, Schafer R, Barnett JB. Production of macrophage IL-1β was inhibited both at the levels of transcription and maturation by caspase-1 following inhalation exposure to isobutyl nitrite Toxicology Letters. 152: 47-56. PMID 15294346 DOI: 10.1016/J.Toxlet.2004.03.020  0.301
2004 Ponnappan U, Yull FE, Soderberg LS. Inhaled isobutyl nitrite inhibited macrophage inducible nitric oxide by blocking NFkappaB signaling and promoting degradation of inducible nitric oxide synthase-2. International Immunopharmacology. 4: 1075-82. PMID 15222982 DOI: 10.1016/J.Intimp.2004.04.014  0.443
2004 Ponnappan S, Uken-Trebilcock G, Lindquist M, Ponnappan U. Tyrosine phosphorylation-dependent activation of NFkappaB is compromised in T cells from the elderly. Experimental Gerontology. 39: 559-66. PMID 15050291 DOI: 10.1016/J.Exger.2003.12.012  0.56
2003 Shi J, Wang J, Zheng H, Ling W, Joseph J, Li D, Mehta JL, Ponnappan U, Lin P, Fink LM, Hauer-Jensen M. Statins increase thrombomodulin expression and function in human endothelial cells by a nitric oxide-dependent mechanism and counteract tumor necrosis factor alpha-induced thrombomodulin downregulation. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 14: 575-85. PMID 12960612 DOI: 10.1097/00001721-200309000-00010  0.353
2002 Soderberg LS, Ponnappan U. Cytotoxicity by nitrite inhalants is not related to peroxynitrite formation. Toxicology Letters. 132: 37-45. PMID 12084618 DOI: 10.1016/S0378-4274(02)00067-X  0.323
2002 Ponnappan U. Ubiquitin-proteasome pathway is compromised in CD45RO+ and CD45RA+ T lymphocyte subsets during aging. Experimental Gerontology. 37: 359-67. PMID 11772523 DOI: 10.1016/S0531-5565(01)00203-0  0.536
2001 Ponnappan U, Soderberg LSF. Inflammatory macrophage nuclear factor-κB and proteasome activity are inhibited following exposure to inhaled isobutyl nitrite Journal of Leukocyte Biology. 69: 639-644. DOI: 10.1189/Jlb.69.4.639  0.464
1999 Ponnappan U, Trebilcock GU, Zheng MZ. Studies into the effect of tyrosine phosphatase inhibitor phenylarsine oxide on NFkappaB activation in T lymphocytes during aging: evidence for altered IkappaB-alpha phosphorylation and degradation. Experimental Gerontology. 34: 95-107. PMID 10197731 DOI: 10.1016/S0531-5565(98)00059-X  0.503
1999 Ponnappan U, Zhong M, Trebilcock GU. Decreased proteasome-mediated degradation in T cells from the elderly: A role in immune senescence. Cellular Immunology. 192: 167-74. PMID 10087185 DOI: 10.1006/Cimm.1998.1418  0.54
1998 Trebilcock GU, Ponnappan U. Nuclear factor-kappaB induction in CD45RO+ and CD45RA+ T cell subsets during aging. Mechanisms of Ageing and Development. 102: 149-63. PMID 9720648 DOI: 10.1016/S0047-6374(97)00160-7  0.412
1998 Tinkle CW, Lipschitz D, Ponnappan U. Decreased association of p56(lck) with CD4 may account for lowered tyrosine kinase activity in mitogen-activated human T lymphocytes during aging Cellular Immunology. 186: 154-160. PMID 9665758 DOI: 10.1006/Cimm.1998.1313  0.445
1998 Ponnappan U. Regulation of transcription factor NF kappa B in immune senescence. Frontiers in Bioscience : a Journal and Virtual Library. 3: d152-68. PMID 9445466 DOI: 10.2741/A271  0.499
1996 Ito Y, Ponnappan U, Lipschitz DA. Excess formation of lysophosphatidic acid with age inhibits myristic acid-induced superoxide anion generation in intact human neutrophils Febs Letters. 394: 149-152. PMID 8843153 DOI: 10.1016/0014-5793(96)00937-4  0.358
1996 Trebilcock GU, Ponnappan U. Evidence for lowered induction of nuclear factor kappa B in activated human T lymphocytes during aging. Gerontology. 42: 137-46. PMID 8796372 DOI: 10.1159/000213785  0.481
1996 Trebilcock GU, Ponnappan U. Induction and regulation of NFkappaB during aging: role of protein kinases. Clinical Immunology and Immunopathology. 79: 87-91. PMID 8612355 DOI: 10.1006/clin.1996.0054  0.345
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