Paul J. Brindley - Publications

Affiliations: 
Biomedical Sciences The George Washington University, Washington, DC, United States 
Area:
Parasitology Biology, Molecular Biology, Microbiology Biology

216 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ittiprasert W, Moescheid MF, Chaparro C, Mann VH, Quack T, Rodpai R, Miller A, Wisitpongpun P, Buakaew W, Mentink-Kane M, Schmid S, Popratiloff A, Grevelding CG, Grunau C, Brindley PJ. Targeted insertion and reporter transgene activity at a gene safe harbor of the human blood fluke, . Cell Reports Methods. 3: 100535. PMID 37533651 DOI: 10.1016/j.crmeth.2023.100535  0.331
2022 Lu Z, Sankaranarayanan G, Rawlinson KA, Offord V, Brindley PJ, Berriman M, Rinaldi G. The Transcriptome of Developing Eggs Reveals Key Mediators in Pathogenesis and Life Cycle Propagation. Frontiers in Tropical Diseases. 2: 713123. PMID 36389622 DOI: 10.3389/fitd.2021.713123  0.313
2022 Ittiprasert W, Chatupheeraphat C, Mann VH, Li W, Miller A, Ogunbayo T, Tran K, Alrefaei YN, Mentink-Kane M, Brindley PJ. RNA-Guided Cas12a- and Cas9-Catalyzed Knockout and Homology Directed Repair of the Omega-1 Locus of the Human Blood Fluke, . International Journal of Molecular Sciences. 23. PMID 35054816 DOI: 10.3390/ijms23020631  0.77
2020 Phumrattanaprapin W, Chaiyadet S, Brindley PJ, Pearson M, Smout MJ, Loukas A, Laha T. Orally administered Bacillus spores expressing an extracellular vesicle-derived tetraspanin protect hamsters against challenge infection with carcinogenic human liver fluke. The Journal of Infectious Diseases. PMID 32813017 DOI: 10.1093/Infdis/Jiaa516  0.335
2020 Nawaratna SSK, McManus DP, Gasser RB, Brindley PJ, Boyle GM, Rivera V, Ranasinghe SL, Jones MK, You H, Gobert GN. Use of Kinase Inhibitors against Schistosomes to Improve and Broaden Praziquantel Efficacy. Parasitology. 1-35. PMID 32741402 DOI: 10.1017/S0031182020001250  0.32
2020 Arunsan P, Chaidee A, Cochran CJ, Mann VH, Tanno T, Kumkhaek C, Smout MJ, Karinshak SE, Rodpai R, Sotillo J, Loukas A, Laha T, Brindley PJ, Ittiprasert W. Liver fluke granulin promotes extracellular vesicle-mediated crosstalk and cellular microenvironment conducive to cholangiocarcinoma. Neoplasia (New York, N.Y.). 22: 203-216. PMID 32244128 DOI: 10.1016/J.Neo.2020.02.004  0.319
2020 Vale N, Gouveia MJ, Gärtner F, Brindley PJ. Oxysterols of helminth parasites and pathogenesis of foodborne hepatic trematodiasis caused by Opisthorchis and Fasciola species. Parasitology Research. PMID 32206886 DOI: 10.1007/S00436-020-06640-4  0.369
2020 Skinner DE, Popratiloff A, Alrefaei YN, Mann VH, Rinaldi G, Brindley PJ. Functional analysis of vasa/PL10-like genes in the ovary of Schistosoma mansoni. Molecular and Biochemical Parasitology. 236: 111259. PMID 31958469 DOI: 10.1016/J.Molbiopara.2020.111259  0.769
2019 Gouveia MJ, Brindley PJ, Rinaldi G, Gärtner F, da Costa JMC, Vale N. Infection with carcinogenic helminth parasites and its production of metabolites induces the formation of DNA-adducts. Infectious Agents and Cancer. 14: 41. PMID 31798678 DOI: 10.1186/S13027-019-0257-2  0.347
2019 Choi YJ, Fontenla S, Fischer PU, Le TH, Costábile A, Blair D, Brindley PJ, Tort JF, Cabada MM, Mitreva M. Adaptive radiation of the flukes of the family Fasciolidae inferred from genome-wide comparisons of key species. Molecular Biology and Evolution. PMID 31501870 DOI: 10.1093/Molbev/Msz204  0.372
2019 Stroehlein AJ, Korhonen PK, Chong TM, Lim YL, Chan KG, Webster B, Rollinson D, Brindley PJ, Gasser RB, Young ND. High-quality Schistosoma haematobium genome achieved by single-molecule and long-range sequencing. Gigascience. 8. PMID 31494670 DOI: 10.1093/Gigascience/Giz108  0.378
2019 Sadaow L, Sanpool O, Rodpai R, Yamasaki H, Ittiprasert W, Mann VH, Brindley PJ, Maleewong W, Intapan PM. Development of an Immunochromatographic Point-of-Care Test for Serodiagnosis of Opisthorchiasis and Clonorchiasis. The American Journal of Tropical Medicine and Hygiene. PMID 31482789 DOI: 10.4269/Ajtmh.19-0446  0.309
2019 Nacif-Pimenta R, da Silva Orfanó A, Mosley IA, Karinshak SE, Ishida K, Mann VH, Coelho PMZ, da Costa JMC, Hsieh MH, Brindley PJ, Rinaldi G. Differential responses of epithelial cells from urinary and biliary tract to eggs of Schistosoma haematobium and S. mansoni. Scientific Reports. 9: 10731. PMID 31341177 DOI: 10.1038/S41598-019-46917-Y  0.327
2019 Tyagi R, Elfawal MA, Wildman SA, Helander J, Bulman CA, Sakanari J, Rosa BA, Brindley PJ, Janetka JW, Aroian RV, Mitreva M. Identification of small molecule enzyme inhibitors as broad-spectrum anthelmintics. Scientific Reports. 9: 9085. PMID 31235822 DOI: 10.1038/S41598-019-45548-7  0.321
2019 Chaiyadet S, Sotillo J, Krueajampa W, Thongsen S, Brindley PJ, Sripa B, Loukas A, Laha T. Vaccination of hamsters with Opisthorchis viverrini extracellular vesicles and vesicle-derived recombinant tetraspanins induces antibodies that block vesicle uptake by cholangiocytes and reduce parasite burden after challenge infection. Plos Neglected Tropical Diseases. 13: e0007450. PMID 31136572 DOI: 10.1371/Journal.Pntd.0007450  0.321
2019 Arunsan P, Ittiprasert W, Smout MJ, Cochran CJ, Mann VH, Chaiyadet S, Karinshak SE, Sripa B, Young ND, Sotillo J, Loukas A, Brindley PJ, Laha T. Programmed knockout mutation of liver fluke granulin attenuates virulence of infection-induced hepatobiliary morbidity. Elife. 8. PMID 30644359 DOI: 10.7554/Elife.41463  0.406
2019 Ittiprasert W, Mann VH, Karinshak SE, Coghlan A, Rinaldi G, Sankaranarayanan G, Chaidee A, Tanno T, KumKhaek C, Prangtaworn P, Mentink-Kane MM, Cochran CJ, Driguez P, Holroyd N, Tracey A, ... ... Brindley PJ, et al. Programmed genome editing of the omega-1 ribonuclease of the blood fluke, . Elife. 8. PMID 30644357 DOI: 10.7554/Elife.41337  0.408
2018 Jenkins TP, Brindley PJ, Gasser RB, Cantacessi C. Helminth Microbiomes - A Hidden Treasure Trove? Trends in Parasitology. 35: 13-22. PMID 30503365 DOI: 10.1016/J.Pt.2018.10.007  0.332
2018 Sripa B, Tangkawattana S, Brindley PJ. Update on Pathogenesis of Opisthorchiasis and Cholangiocarcinoma. Advances in Parasitology. 102: 97-113. PMID 30442312 DOI: 10.1016/Bs.Apar.2018.10.001  0.328
2018 Laha T, Brindley PJ, Suyapoh W, Suttiprapa S. RNA Interference as an Approach to Functional Genomics Genetic Manipulation of Opisthorchis viverrini. Advances in Parasitology. 102: 25-43. PMID 30442309 DOI: 10.1016/Bs.Apar.2018.06.001  0.414
2018 Saltykova IV, Petrov VA, Brindley PJ. Opisthorchiasis and the Microbiome. Advances in Parasitology. 102: 1-23. PMID 30442306 DOI: 10.1016/Bs.Apar.2018.07.001  0.342
2018 Upontain S, Sereerak P, Laha T, Sripa B, Tangkawatana P, Brindley PJ, Tangkawatana S. Granulin Expression in Hamsters during Opisthorchis viverrini Infection-Induced Cholangiocarcinogenesis Asian Pacific Journal of Cancer Prevention : Apjcp. 19: 2437-2445. PMID 30255697 DOI: 10.22034/Apjcp.2018.19.9.2437  0.348
2018 Jenkins TP, Peachey LE, Ajami NJ, MacDonald AS, Hsieh MH, Brindley PJ, Cantacessi C, Rinaldi G. Schistosoma mansoni infection is associated with quantitative and qualitative modifications of the mammalian intestinal microbiota. Scientific Reports. 8: 12072. PMID 30104612 DOI: 10.1038/S41598-018-30412-X  0.34
2018 Stroehlein AJ, Young ND, Korhonen PK, Hall RS, Jex AR, Webster BL, Rollinson D, Brindley PJ, Gasser RB. The small RNA complement of adult Schistosoma haematobium. Plos Neglected Tropical Diseases. 12: e0006535. PMID 29813122 DOI: 10.1371/Journal.Pntd.0006535  0.399
2018 Yan HB, Smout MJ, Ju C, Folley AE, Skinner DE, Mann VH, Loukas A, Hu W, Brindley PJ, Rinaldi G. Developmental sensitivity in to puromycin to establish drug selection of transgenic schistosomes. Antimicrobial Agents and Chemotherapy. PMID 29760143 DOI: 10.1128/Aac.02568-17  0.709
2018 Tyagi R, Maddirala AR, Elfawal M, Fischer C, Bulman C, Rosa BA, Gao X, Chugani R, Zhou M, Helander J, Brindley P, Tseng CC, Greig IR, Sakanari J, Wildman SA, et al. Small molecule inhibitors of metabolic enzymes repurposed as a new class of anthelmintics. Acs Infectious Diseases. PMID 29718656 DOI: 10.1021/Acsinfecdis.8B00090  0.304
2018 Haugen B, Karinshak SE, Mann VH, Popratiloff A, Loukas A, Brindley PJ, Smout MJ. Granulin Secreted by the Food-Borne Liver FlukePromotes Angiogenesis in Human Endothelial Cells. Frontiers in Medicine. 5: 30. PMID 29503819 DOI: 10.3389/Fmed.2018.00030  0.302
2017 Maggioli G, Rinaldi G, Giaudrone I, Berasain P, Tort JF, Brindley PJ, Carmona C. Expression, purification and characterization of two leucine aminopeptidases of the blood fluke, Schistosoma mansoni. Molecular and Biochemical Parasitology. PMID 29169803 DOI: 10.1016/J.Molbiopara.2017.11.006  0.407
2017 Chaiyadet S, Krueajampa W, Hipkaeo W, Plosan Y, Piratae S, Sotillo J, Smout M, Sripa B, Brindley PJ, Loukas A, Laha T. Suppression of mRNAs encoding CD63 family tetraspanins from the carcinogenic liver fluke Opisthorchis viverrini results in distinct tegument phenotypes. Scientific Reports. 7: 14342. PMID 29084967 DOI: 10.1038/S41598-017-13527-5  0.35
2017 Gouveia MJ, Pakharukova MY, Laha T, Sripa B, Maksimova GA, Rinaldi G, Brindley PJ, Mordvinov VA, Amaro T, Santos LL, Costa JMCD, Vale N. Infection with Opisthorchis felineus induces intraepithelial neoplasia of the biliary tract in a rodent model. Carcinogenesis. 38: 929-937. PMID 28910999 DOI: 10.1093/Carcin/Bgx042  0.339
2017 Brindley PJ, Loukas A. Helminth infection-induced malignancy. Plos Pathogens. 13: e1006393. PMID 28750101 DOI: 10.1371/Journal.Ppat.1006393  0.33
2017 Deenonpoe R, Mairiang E, Mairiang P, Pairojkul C, Chamgramol Y, Rinaldi G, Loukas A, Brindley PJ, Sripa B. Elevated prevalence of Helicobacter species and virulence factors in opisthorchiasis and associated hepatobiliary disease. Scientific Reports. 7: 42744. PMID 28198451 DOI: 10.1038/Srep42744  0.304
2017 McNulty SN, Tort JF, Rinaldi G, Fischer K, Rosa BA, Smircich P, Fontenla S, Choi YJ, Tyagi R, Hallsworth-Pepin K, Mann VH, Kammili L, Latham PS, Dell'Oca N, Dominguez F, ... ... Brindley PJ, et al. Genomes of Fasciola hepatica from the Americas Reveal Colonization with Neorickettsia Endobacteria Related to the Agents of Potomac Horse and Human Sennetsu Fevers. Plos Genetics. 13: e1006537. PMID 28060841 DOI: 10.1371/Journal.Pgen.1006537  0.398
2016 van Tong H, Brindley PJ, Meyer CG, Velavan TP. Parasite Infection, Carcinogenesis and Human Malignancy. Ebiomedicine. PMID 27956028 DOI: 10.1016/J.Ebiom.2016.11.034  0.362
2016 Sripa B, Deenonpoe R, Brindley PJ. Co-infections with liver fluke and Helicobacter species: A paradigm change in pathogenesis of opisthorchiasis and cholangiocarcinoma? Parasitology International. PMID 27919744 DOI: 10.1016/J.Parint.2016.11.016  0.317
2016 Suttiprapa S, Rinaldi G, Tsai IJ, Mann VH, Dubrovsky L, Yan HB, Holroyd N, Huckvale T, Durrant C, Protasio AV, Pushkarsky T, Iordanskiy S, Berriman M, Bukrinsky MI, Brindley PJ. HIV-1 Integrates Widely throughout the Genome of the Human Blood Fluke Schistosoma mansoni. Plos Pathogens. 12: e1005931. PMID 27764257 DOI: 10.1371/Journal.Ppat.1005931  0.345
2016 Saltykova IV, Petrov VA, Logacheva MD, Ivanova PG, Merzlikin NV, Sazonov AE, Ogorodova LM, Brindley PJ. Biliary Microbiota, Gallstone Disease and Infection with Opisthorchis felineus. Plos Neglected Tropical Diseases. 10: e0004809. PMID 27447938 DOI: 10.1371/Journal.Pntd.0004809  0.317
2016 Hanpanich P, Laha T, Sripa B, Mairiang E, Sereerak P, Upontain S, Tangkawattana P, Brindley PJ, Tangkawattana S. Decreased risk of Cholangiocarcinogenesis following repeated cycles of Opisthorchis viverrini Infection-Praziquantel treatment: Magnetic resonance imaging (Mri) And histopathological study in a hamster model. Parasitology International. PMID 27143606 DOI: 10.1016/J.Parint.2016.04.012  0.306
2016 Teimoori S, Arimatsu Y, Laha T, Kaewkes S, Sereerak P, Sripa M, Tangkawattana S, Brindley PJ, Sripa B. Chicken IgY-based coproantigen capture ELISA for diagnosis of human opisthorchiasis. Parasitology International. PMID 27140305 DOI: 10.1016/J.Parint.2015.10.011  0.305
2016 Saltykova IV, Ogorodova LM, Ivanov VV, Bogdanov AO, Gereng EA, Perina EA, Brindley PJ, Sazonov AE. Carbonyl stress phenomena during chronic infection with Opisthorchis felineus. Parasitology International. PMID 26773869 DOI: 10.1016/J.Parint.2016.01.002  0.326
2016 Papatpremsiri A, Junpue P, Loukas A, Brindley PJ, Bethony JM, Sripa B, Laha T. Immunization and challenge shown by hamsters infected with Opisthorchis viverrini following exposure to gamma-irradiated metacercariae of this carcinogenic liver fluke. Journal of Helminthology. 90: 39-47. PMID 25315797 DOI: 10.1017/S0022149X14000741  0.314
2015 Brindley PJ, Costa JMCD, Sripa B. Why Does Infection With Some Helminths Cause Cancer? Trends in Cancer. 1: 174-182. PMID 28741473 DOI: 10.1016/J.Trecan.2015.08.011  0.327
2015 Pakharukova MY, Vavilin VA, Sripa B, Laha T, Brindley PJ, Mordvinov VA. Functional Analysis of the Unique Cytochrome P450 of the Liver Fluke Opisthorchis felineus. Plos Neglected Tropical Diseases. 9: e0004258. PMID 26625139 DOI: 10.1371/Journal.Pntd.0004258  0.366
2015 Smout MJ, Sotillo J, Laha T, Papatpremsiri A, Rinaldi G, Pimenta RN, Chan LY, Johnson MS, Turnbull L, Whitchurch CB, Giacomin PR, Moran CS, Golledge J, Daly N, Sripa B, ... ... Brindley PJ, et al. Carcinogenic Parasite Secretes Growth Factor That Accelerates Wound Healing and Potentially Promotes Neoplasia. Plos Pathogens. 11: e1005209. PMID 26485648 DOI: 10.1371/Journal.Ppat.1005209  0.318
2015 Santos J, Chaves J, Araújo H, Vale N, Costa JM, Brindley PJ, Lopes C, Naples J, Shiff C, Dupret J, Santos LL. Comparison of findings using ultrasonography and cystoscopy in urogenital schistosomiasis in a public health centre in rural Angola. South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde. 105: 312-5. PMID 26294877 DOI: 10.7196/Samj.8564  0.317
2015 Rinaldi G, Loukas A, Brindley PJ, Irelan JT, Smout MJ. Viability of developmental stages of Schistosoma mansoni quantified with xCELLigence worm real-time motility assay (xWORM). International Journal For Parasitology. Drugs and Drug Resistance. 5: 141-8. PMID 26288742 DOI: 10.1016/J.Ijpddr.2015.07.002  0.347
2015 Chaiyadet S, Sotillo J, Smout M, Cantacessi C, Jones MK, Johnson MS, Turnbull L, Whitchurch CB, Potriquet J, Laohaviroj M, Mulvenna J, Brindley PJ, Bethony JM, Laha T, Sripa B, et al. Carcinogenic Liver Fluke Secretes Extracellular Vesicles That Promote Cholangiocytes to Adopt a Tumorigenic Phenotype. The Journal of Infectious Diseases. PMID 25985904 DOI: 10.1093/Infdis/Jiv291  0.343
2015 Wang J, Wang S, Liu X, Xu B, Chai R, Zhou P, Ju C, Sun J, Brindley PJ, Hu W. Intake of Erythrocytes Required for Reproductive Development of Female Schistosoma japonicum. Plos One. 10: e0126822. PMID 25978643 DOI: 10.1371/Journal.Pone.0126822  0.333
2015 Jurberg AD, Brindley PJ. Gene function in schistosomes: recent advances toward a cure. Frontiers in Genetics. 6: 144. PMID 25926850 DOI: 10.3389/Fgene.2015.00144  0.354
2015 Rinaldi G, Yan H, Nacif-Pimenta R, Matchimakul P, Bridger J, Mann VH, Smout MJ, Brindley PJ, Knight M. Cytometric analysis, genetic manipulation and antibiotic selection of the snail embryonic cell line Bge from Biomphalaria glabrata, the intermediate host of Schistosoma mansoni. International Journal For Parasitology. 45: 527-35. PMID 25907768 DOI: 10.1016/J.Ijpara.2015.02.012  0.328
2015 Nguyen TT, Arimatsu Y, Hong SJ, Brindley PJ, Blair D, Laha T, Sripa B. Genome-wide characterization of microsatellites and marker development in the carcinogenic liver fluke Clonorchis sinensis. Parasitology Research. 114: 2263-72. PMID 25782682 DOI: 10.1007/S00436-015-4419-X  0.329
2015 Gouveia MJ, Santos J, Brindley PJ, Rinaldi G, Lopes C, Santos LL, da Costa JM, Vale N. Estrogen-like metabolites and DNA-adducts in urogenital schistosomiasis-associated bladder cancer. Cancer Letters. 359: 226-32. PMID 25615421 DOI: 10.1016/J.Canlet.2015.01.018  0.311
2015 Papatpremsiri A, Smout MJ, Loukas A, Brindley PJ, Sripa B, Laha T. Suppression of Ov-grn-1 encoding granulin of Opisthorchis viverrini inhibits proliferation of biliary epithelial cells. Experimental Parasitology. 148: 17-23. PMID 25450776 DOI: 10.1016/J.Exppara.2014.11.004  0.359
2015 Martin J, Rosa BA, Ozersky P, Hallsworth-Pepin K, Zhang X, Bhonagiri-Palsikar V, Tyagi R, Wang Q, Choi YJ, Gao X, McNulty SN, Brindley PJ, Mitreva M. Helminth.net: expansions to Nematode.net and an introduction to Trematode.net. Nucleic Acids Research. 43: D698-706. PMID 25392426 DOI: 10.1093/Nar/Gku1128  0.322
2015 Rinaldi G, Young ND, Honeycutt JD, Brindley PJ, Gasser RB, Hsieh MH. New research tools for urogenital schistosomiasis. The Journal of Infectious Diseases. 211: 861-9. PMID 25240172 DOI: 10.1093/Infdis/Jiu527  0.413
2014 Correia da Costa JM, Vale N, Gouveia MJ, Botelho MC, Sripa B, Santos LL, Santos JH, Rinaldi G, Brindley PJ. Schistosome and liver fluke derived catechol-estrogens and helminth associated cancers. Frontiers in Genetics. 5: 444. PMID 25566326 DOI: 10.3389/Fgene.2014.00444  0.361
2014 Dell'Oca N, Basika T, Corvo I, Castillo E, Brindley PJ, Rinaldi G, Tort JF. RNA interference in Fasciola hepatica newly excysted juveniles: long dsRNA induces more persistent silencing than siRNA. Molecular and Biochemical Parasitology. 197: 28-35. PMID 25307443 DOI: 10.1016/J.Molbiopara.2014.10.001  0.38
2014 Yan HB, Lou ZZ, Li L, Brindley PJ, Zheng Y, Luo X, Hou J, Guo A, Jia WZ, Cai X. Genome-wide analysis of regulatory proteases sequences identified through bioinformatics data mining in Taenia solium. Bmc Genomics. 15: 428. PMID 24899069 DOI: 10.1186/1471-2164-15-428  0.383
2014 Zeraik AE, Galkin VE, Rinaldi G, Garratt RC, Smout MJ, Loukas A, Mann VH, Araujo AP, DeMarco R, Brindley PJ. Reversible paralysis of Schistosoma mansoni by forchlorfenuron, a phenylurea cytokinin that affects septins. International Journal For Parasitology. 44: 523-31. PMID 24768753 DOI: 10.1016/J.Ijpara.2014.03.010  0.334
2014 Skinner DE, Rinaldi G, Koziol U, Brehm K, Brindley PJ. How might flukes and tapeworms maintain genome integrity without a canonical piRNA pathway? Trends in Parasitology. 30: 123-9. PMID 24485046 DOI: 10.1016/J.Pt.2014.01.001  0.719
2014 Mann VH, Suttiprapa S, Skinner DE, Brindley PJ, Rinaldi G. Pseudotyped murine leukemia virus for schistosome transgenesis: approaches, methods and perspectives. Transgenic Research. 23: 539-56. PMID 24474164 DOI: 10.1007/S11248-013-9779-3  0.749
2014 Thi Phung L, Loukas A, Brindley PJ, Sripa B, Laha T. Retrotransposon OV-RTE-1 from the carcinogenic liver fluke Opisthorchis viverrini: potential target for DNA-based diagnosis. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 21: 443-51. PMID 24394447 DOI: 10.1016/J.Meegid.2013.12.015  0.377
2013 Zeraik AE, Rinaldi G, Mann VH, Popratiloff A, Araujo AP, Demarco R, Brindley PJ. Septins of Platyhelminths: identification, phylogeny, expression and localization among developmental stages of Schistosoma mansoni. Plos Neglected Tropical Diseases. 7: e2602. PMID 24367716 DOI: 10.1371/Journal.Pntd.0002602  0.324
2013 Xiao N, Remais JV, Brindley PJ, Qiu DC, Carlton EJ, Li RZ, Lei Y, Blair D. Approaches to genotyping individual miracidia of Schistosoma japonicum. Parasitology Research. 112: 3991-9. PMID 24013341 DOI: 10.1007/S00436-013-3587-9  0.351
2013 Plieskatt JL, Deenonpoe R, Mulvenna JP, Krause L, Sripa B, Bethony JM, Brindley PJ. Infection with the carcinogenic liver fluke Opisthorchis viverrini modifies intestinal and biliary microbiome. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4572-84. PMID 23925654 DOI: 10.1096/Fj.13-232751  0.365
2013 You H, McManus DP, Hu W, Smout MJ, Brindley PJ, Gobert GN. Transcriptional responses of in vivo praziquantel exposure in schistosomes identifies a functional role for calcium signalling pathway member CamKII. Plos Pathogens. 9: e1003254. PMID 23555262 DOI: 10.1371/Journal.Ppat.1003254  0.363
2013 Botelho MC, Vale N, Gouveia MJ, Rinaldi G, Santos J, Santos LL, Gomes P, Brindley PJ, Correia da Costa JM. Tumour-like phenotypes in urothelial cells after exposure to antigens from eggs of Schistosoma haematobium: an oestrogen-DNA adducts mediated pathway? International Journal For Parasitology. 43: 17-26. PMID 23260770 DOI: 10.1016/J.Ijpara.2012.10.023  0.33
2013 Okumura-Noji K, Miura Y, Lu R, Asai K, Ohta N, Brindley PJ, Yokoyama S. CD36-related protein in Schistosoma japonicum: candidate mediator of selective cholesteryl ester uptake from high-density lipoprotein for egg maturation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1236-44. PMID 23195036 DOI: 10.1096/Fj.12-219816  0.324
2012 Piratae S, Tesana S, Jones MK, Brindley PJ, Loukas A, Lovas E, Eursitthichai V, Sripa B, Thanasuwan S, Laha T. Molecular characterization of a tetraspanin from the human liver fluke, Opisthorchis viverrini. Plos Neglected Tropical Diseases. 6: e1939. PMID 23236532 DOI: 10.1371/Journal.Pntd.0001939  0.32
2012 Sripa B, Brindley PJ, Mulvenna J, Laha T, Smout MJ, Mairiang E, Bethony JM, Loukas A. The tumorigenic liver fluke Opisthorchis viverrini--multiple pathways to cancer. Trends in Parasitology. 28: 395-407. PMID 22947297 DOI: 10.1016/J.Pt.2012.07.006  0.322
2012 Rinaldi G, Eckert SE, Tsai IJ, Suttiprapa S, Kines KJ, Tort JF, Mann VH, Turner DJ, Berriman M, Brindley PJ. Germline transgenesis and insertional mutagenesis in Schistosoma mansoni mediated by murine leukemia virus. Plos Pathogens. 8: e1002820. PMID 22911241 DOI: 10.1371/Journal.Ppat.1002820  0.449
2012 Skinner DE, Rinaldi G, Suttiprapa S, Mann VH, Smircich P, Cogswell AA, Williams DL, Brindley PJ. Vasa-Like DEAD-Box RNA Helicases of Schistosoma mansoni. Plos Neglected Tropical Diseases. 6: e1686. PMID 22720105 DOI: 10.1371/Journal.Pntd.0001686  0.751
2012 Young ND, Jex AR, Li B, Liu S, Yang L, Xiong Z, Li Y, Cantacessi C, Hall RS, Xu X, Chen F, Wu X, Zerlotini A, Oliveira G, Hofmann A, ... ... Brindley PJ, et al. Whole-genome sequence of Schistosoma haematobium. Nature Genetics. 44: 221-5. PMID 22246508 DOI: 10.1038/Ng.1065  0.391
2012 Rinaldi G, Suttiprapa S, Tort JF, Folley AE, Skinner DE, Brindley PJ. An antibiotic selection marker for schistosome transgenesis. International Journal For Parasitology. 42: 123-30. PMID 22155152 DOI: 10.1016/J.Ijpara.2011.11.005  0.693
2012 Duvoisin R, Ayuk MA, Rinaldi G, Suttiprapa S, Mann VH, Lee CM, Harris N, Brindley PJ. Human U6 promoter drives stronger shRNA activity than its schistosome orthologue in Schistosoma mansoni and human fibrosarcoma cells. Transgenic Research. 21: 511-21. PMID 21953124 DOI: 10.1007/S11248-011-9548-0  0.41
2012 Suttiprapa S, Rinaldi G, Brindley PJ. Prototypic chromatin insulator cHS4 protects retroviral transgene from silencing in Schistosoma mansoni. Transgenic Research. 21: 555-66. PMID 21918820 DOI: 10.1007/S11248-011-9556-0  0.404
2012 Suttiprapa S, Rinaldi G, Brindley PJ. Genetic manipulation of schistosomes--progress with integration competent vectors. Parasitology. 139: 641-50. PMID 21854676 DOI: 10.1017/S003118201100134X  0.397
2012 Mairiang E, Laha T, Bethony JM, Thinkhamrop B, Kaewkes S, Sithithaworn P, Tesana S, Loukas A, Brindley PJ, Sripa B. Ultrasonography assessment of hepatobiliary abnormalities in 3359 subjects with Opisthorchis viverrini infection in endemic areas of Thailand. Parasitology International. 61: 208-11. PMID 21771664 DOI: 10.1016/J.Parint.2011.07.009  0.301
2012 Suttiprapa S, Matchimakul P, Loukas A, Laha T, Wongkham S, Kaewkes S, Brindley PJ, Sripa B. Molecular expression and enzymatic characterization of thioredoxin from the carcinogenic human liver fluke Opisthorchis viverrini. Parasitology International. 61: 101-6. PMID 21740981 DOI: 10.1016/J.Parint.2011.06.018  0.363
2012 Sripa J, Brindley PJ, Sripa B, Loukas A, Kaewkes S, Laha T. Evaluation of liver fluke recombinant cathepsin B-1 protease as a serodiagnostic antigen for human opisthorchiasis. Parasitology International. 61: 191-5. PMID 21704728 DOI: 10.1016/J.Parint.2011.05.009  0.347
2012 Rinaldi G, Suttiprapa S, Tort JF, Folley AE, Skinner DE, Brindley PJ. Corrigendum to 'An antibiotic selection marker for schistosome transgenesis' [Int. J. Parasitol. 42 (2012) 123-130] International Journal For Parasitology. 42: 707. DOI: 10.1016/J.Ijpara.2012.04.007  0.675
2011 Alrefaei YN, Okatcha TI, Skinner DE, Brindley PJ. Progress with schistosome transgenesis. MemóRias Do Instituto Oswaldo Cruz. 106: 785-93. PMID 22124549 DOI: 10.1590/S0074-02762011000700002  0.774
2011 Rinaldi G, Okatcha TI, Popratiloff A, Ayuk MA, Suttiprapa S, Mann VH, Liang YS, Lewis FA, Loukas A, Brindley PJ. Genetic manipulation of Schistosoma haematobium, the neglected schistosome. Plos Neglected Tropical Diseases. 5: e1348. PMID 22022628 DOI: 10.1371/Journal.Pntd.0001348  0.38
2011 Mann VH, Suttiprapa S, Rinaldi G, Brindley PJ. Establishing transgenic schistosomes. Plos Neglected Tropical Diseases. 5: e1230. PMID 21912709 DOI: 10.1371/Journal.Pntd.0001230  0.402
2011 Botelho MC, Machado JC, Brindley PJ, Correia da Costa JM. Targeting molecular signaling pathways of Schistosoma haemotobium infection in bladder cancer. Virulence. 2: 267-79. PMID 21788729 DOI: 10.4161/Viru.2.4.16734  0.317
2011 Nair SS, Bommana A, Pakala SB, Ohshiro K, Lyon AJ, Suttiprapa S, Periago MV, Laha T, Hotez PJ, Bethony JM, Sripa B, Brindley PJ, Kumar R. Inflammatory response to liver fluke Opisthorchis viverrini in mice depends on host master coregulator MTA1, a marker for parasite-induced cholangiocarcinoma in humans. Hepatology (Baltimore, Md.). 54: 1388-97. PMID 21725997 DOI: 10.1002/Hep.24518  0.34
2011 Loukas A, Gaze S, Mulvenna JP, Gasser RB, Brindley PJ, Doolan DL, Bethony JM, Jones MK, Gobert GN, Driguez P, McManus DP, Hotez PJ. Vaccinomics for the major blood feeding helminths of humans. Omics : a Journal of Integrative Biology. 15: 567-77. PMID 21679087 DOI: 10.1089/Omi.2010.0150  0.387
2011 Sripa J, Pinlaor P, Brindley PJ, Sripa B, Kaewkes S, Robinson MW, Young ND, Gasser RB, Loukas A, Laha T. RNA interference targeting cathepsin B of the carcinogenic liver fluke, Opisthorchis viverrini. Parasitology International. 60: 283-8. PMID 21565281 DOI: 10.1016/J.Parint.2011.04.003  0.383
2011 Nair SS, Bommana A, Bethony JM, Lyon AJ, Ohshiro K, Pakala SB, Rinaldi G, Keegan B, Suttiprapa S, Periago MV, Hotez PJ, Brindley PJ, Kumar R. The metastasis-associated protein-1 gene encodes a host permissive factor for schistosomiasis, a leading global cause of inflammation and cancer. Hepatology (Baltimore, Md.). 54: 285-95. PMID 21488078 DOI: 10.1002/Hep.24354  0.39
2011 Ayuk MA, Suttiprapa S, Rinaldi G, Mann VH, Lee CM, Brindley PJ. Schistosoma mansoni U6 gene promoter-driven short hairpin RNA induces RNA interference in human fibrosarcoma cells and schistosomules. International Journal For Parasitology. 41: 783-9. PMID 21447344 DOI: 10.1016/J.Ijpara.2011.02.004  0.394
2011 Smout MJ, Sripa B, Laha T, Mulvenna J, Gasser RB, Young ND, Bethony JM, Brindley PJ, Loukas A. Infection with the carcinogenic human liver fluke, Opisthorchis viverrini. Molecular Biosystems. 7: 1367-75. PMID 21311794 DOI: 10.1039/C0Mb00295J  0.365
2011 Xiao N, Remais J, Brindley PJ, Qiu D, Spear R, Lei Y, Blair D. Polymorphic microsatellites in the human bloodfluke, Schistosoma japonicum, identified using a genomic resource. Parasites & Vectors. 4: 13. PMID 21299863 DOI: 10.1186/1756-3305-4-13  0.309
2011 Rinaldi G, Suttiprapa S, Brindley PJ. Quantitative retrotransposon anchored PCR confirms transduction efficiency of transgenes in adult Schistosoma mansoni. Molecular and Biochemical Parasitology. 177: 70-6. PMID 21251928 DOI: 10.1016/J.Molbiopara.2011.01.007  0.382
2011 Sripa B, Bethony JM, Sithithaworn P, Kaewkes S, Mairiang E, Loukas A, Mulvenna J, Laha T, Hotez PJ, Brindley PJ. Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos. Acta Tropica. 120: S158-68. PMID 20655862 DOI: 10.1016/J.Actatropica.2010.07.006  0.313
2010 Yang S, Brindley PJ, Zeng Q, Li Y, Zhou J, Liu Y, Liu B, Cai L, Zeng T, Wei Q, Lan L, McManus DP. Transduction of Schistosoma japonicum schistosomules with vesicular stomatitis virus glycoprotein pseudotyped murine leukemia retrovirus and expression of reporter human telomerase reverse transcriptase in the transgenic schistosomes. Molecular and Biochemical Parasitology. 174: 109-16. PMID 20692298 DOI: 10.1016/J.Molbiopara.2010.07.007  0.45
2010 Young ND, Jex AR, Cantacessi C, Campbell BE, Laha T, Sohn WM, Sripa B, Loukas A, Brindley PJ, Gasser RB. Progress on the transcriptomics of carcinogenic liver flukes of humans--unique biological and biotechnological prospects. Biotechnology Advances. 28: 859-70. PMID 20673796 DOI: 10.1016/J.Biotechadv.2010.07.006  0.362
2010 Chuan J, Feng Z, Brindley PJ, McManus DP, Han Z, Jianxin P, Hu W. Our wormy world genomics, proteomics and transcriptomics in East and southeast Asia. Advances in Parasitology. 73: 327-71. PMID 20627147 DOI: 10.1016/S0065-308X(10)73011-6  0.385
2010 Young ND, Campbell BE, Hall RS, Jex AR, Cantacessi C, Laha T, Sohn WM, Sripa B, Loukas A, Brindley PJ, Gasser RB. Unlocking the transcriptomes of two carcinogenic parasites, Clonorchis sinensis and Opisthorchis viverrini. Plos Neglected Tropical Diseases. 4: e719. PMID 20582164 DOI: 10.1371/Journal.Pntd.0000719  0.403
2010 Gilbert C, Schaack S, Pace JK, Brindley PJ, Feschotte C. A role for host-parasite interactions in the horizontal transfer of transposons across phyla. Nature. 464: 1347-50. PMID 20428170 DOI: 10.1038/Nature08939  0.371
2010 Tchoubrieva EB, Ong PC, Pike RN, Brindley PJ, Kalinna BH. Vector-based RNA interference of cathepsin B1 in Schistosoma mansoni. Cellular and Molecular Life Sciences : Cmls. 67: 3739-48. PMID 20339897 DOI: 10.1007/S00018-010-0345-3  0.402
2010 Kines KJ, Rinaldi G, Okatcha TI, Morales ME, Mann VH, Tort JF, Brindley PJ. Electroporation facilitates introduction of reporter transgenes and virions into schistosome eggs. Plos Neglected Tropical Diseases. 4: e593. PMID 20126309 DOI: 10.1371/Journal.Pntd.0000593  0.656
2010 Sripa J, Laha T, To J, Brindley PJ, Sripa B, Kaewkes S, Dalton JP, Robinson MW. Secreted cysteine proteases of the carcinogenic liver fluke, Opisthorchis viverrini: regulation of cathepsin F activation by autocatalysis and trans-processing by cathepsin B. Cellular Microbiology. 12: 781-95. PMID 20070308 DOI: 10.1111/J.1462-5822.2010.01433.X  0.304
2010 Mulvenna J, Sripa B, Brindley PJ, Gorman J, Jones MK, Colgrave ML, Jones A, Nawaratna S, Laha T, Suttiprapa S, Smout MJ, Loukas A. The secreted and surface proteomes of the adult stage of the carcinogenic human liver fluke Opisthorchis viverrini. Proteomics. 10: 1063-78. PMID 20049860 DOI: 10.1002/Pmic.200900393  0.373
2010 Mann VH, Morales ME, Rinaldi G, Brindley PJ. Culture for genetic manipulation of developmental stages of Schistosoma mansoni. Parasitology. 137: 451-62. PMID 19765348 DOI: 10.1017/S0031182009991211  0.699
2009 Brindley PJ, Mitreva M, Ghedin E, Lustigman S. Helminth genomics: The implications for human health. Plos Neglected Tropical Diseases. 3: e538. PMID 19855829 DOI: 10.1371/Journal.Pntd.0000538  0.417
2009 Smout MJ, Laha T, Mulvenna J, Sripa B, Suttiprapa S, Jones A, Brindley PJ, Loukas A. A granulin-like growth factor secreted by the carcinogenic liver fluke, Opisthorchis viverrini, promotes proliferation of host cells. Plos Pathogens. 5: e1000611. PMID 19816559 DOI: 10.1371/Journal.Ppat.1000611  0.35
2009 Copeland CS, Marz M, Rose D, Hertel J, Brindley PJ, Santana CB, Kehr S, Attolini CS, Stadler PF. Homology-based annotation of non-coding RNAs in the genomes of Schistosoma mansoni and Schistosoma japonicum. Bmc Genomics. 10: 464. PMID 19814823 DOI: 10.1186/1471-2164-10-464  0.404
2009 Sripa B, Mairiang E, Thinkhamrop B, Laha T, Kaewkes S, Sithithaworn P, Tessana S, Loukas A, Brindley PJ, Bethony JM. Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6. Hepatology (Baltimore, Md.). 50: 1273-81. PMID 19676135 DOI: 10.1002/Hep.23134  0.308
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2009 Rinaldi G, Morales ME, Alrefaei YN, Cancela M, Castillo E, Dalton JP, Tort JF, Brindley PJ. RNA interference targeting leucine aminopeptidase blocks hatching of Schistosoma mansoni eggs. Molecular and Biochemical Parasitology. 167: 118-26. PMID 19463860 DOI: 10.1016/J.Molbiopara.2009.05.002  0.787
2009 Gobert GN, Moertel L, Brindley PJ, McManus DP. Developmental gene expression profiles of the human pathogen Schistosoma japonicum. Bmc Genomics. 10: 128. PMID 19320991 DOI: 10.1186/1471-2164-10-128  0.401
2009 Pinlaor P, Kaewpitoon N, Laha T, Sripa B, Kaewkes S, Morales ME, Mann VH, Parriott SK, Suttiprapa S, Robinson MW, To J, Dalton JP, Loukas A, Brindley PJ. Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini. Plos Neglected Tropical Diseases. 3: e398. PMID 19308250 DOI: 10.1371/Journal.Pntd.0000398  0.752
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2009 Suttiprapa S, Mulvenna J, Huong NT, Pearson MS, Brindley PJ, Laha T, Wongkham S, Kaewkes S, Sripa B, Loukas A. Ov-APR-1, an aspartic protease from the carcinogenic liver fluke, Opisthorchis viverrini: functional expression, immunolocalization and subsite specificity. The International Journal of Biochemistry & Cell Biology. 41: 1148-56. PMID 18996218 DOI: 10.1016/J.Biocel.2008.10.013  0.351
2008 Hotez PJ, Bethony JM, Oliveira SC, Brindley PJ, Loukas A. Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis. Expert Review of Vaccines. 7: 745-52. PMID 18665774 DOI: 10.1586/14760584.7.6.745  0.341
2008 Rinaldi G, Morales ME, Cancela M, Castillo E, Brindley PJ, Tort JF. Development of functional genomic tools in trematodes: RNA interference and luciferase reporter gene activity in Fasciola hepatica. Plos Neglected Tropical Diseases. 2: e260. PMID 18612418 DOI: 10.1371/Journal.Pntd.0000260  0.708
2008 Yin M, Hu W, Mo X, Wang S, Brindley PJ, McManus DP, Davis GM, Feng Z, Blair D. Multiple near-identical genotypes of Schistosoma japonicum can occur in snails and have implications for population-genetic analyses. International Journal For Parasitology. 38: 1681-91. PMID 18590733 DOI: 10.1016/J.Ijpara.2008.05.015  0.321
2008 Suttiprapa S, Loukas A, Laha T, Wongkham S, Kaewkes S, Gaze S, Brindley PJ, Sripa B. Characterization of the antioxidant enzyme, thioredoxin peroxidase, from the carcinogenic human liver fluke, Opisthorchis viverrini. Molecular and Biochemical Parasitology. 160: 116-22. PMID 18538872 DOI: 10.1016/J.Molbiopara.2008.04.010  0.327
2008 Kines KJ, Morales ME, Mann VH, Gobert GN, Brindley PJ. Integration of reporter transgenes into Schistosoma mansoni chromosomes mediated by pseudotyped murine leukemia virus. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2936-48. PMID 18403630 DOI: 10.1096/Fj.08-108308  0.685
2008 Hotez PJ, Brindley PJ, Bethony JM, King CH, Pearce EJ, Jacobson J. Helminth infections: the great neglected tropical diseases. The Journal of Clinical Investigation. 118: 1311-21. PMID 18382743 DOI: 10.1172/Jci34261  0.392
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2008 Morales ME, Rinaldi G, Gobert GN, Kines KJ, Tort JF, Brindley PJ. RNA interference of Schistosoma mansoni cathepsin D, the apical enzyme of the hemoglobin proteolysis cascade Molecular and Biochemical Parasitology. 157: 160-168. PMID 18067980 DOI: 10.1016/J.Molbiopara.2007.10.009  0.663
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2008 Fan J, Yang W, Brindley PJ. Lysophospholipase from the human blood fluke, Schistosoma japonicum International Journal of Infectious Diseases. 12: 143-151. PMID 17709268 DOI: 10.1016/J.Ijid.2007.05.005  0.4
2008 Hu W, Brindley PJ, McManus DP, Feng Z, Han ZG. Schistosome transcriptomes: new insights into the parasite and schistosomiasis. Trends in Molecular Medicine. 10: 217-25. PMID 15121048 DOI: 10.1016/J.Molmed.2004.03.002  0.383
2007 Laha T, Loukas A, Wattanasatitarpa S, Somprakhon J, Kewgrai N, Sithithaworn P, Kaewkes S, Mitreva M, Brindley PJ. The bandit, a new DNA transposon from a hookworm - Possible horizontal genetic transfer between host and parasite Plos Neglected Tropical Diseases. 1. PMID 17989781 DOI: 10.1371/Journal.Pntd.0000035  0.426
2007 Laha T, Pinlaor P, Mulvenna J, Sripa B, Sripa M, Smout MJ, Gasser RB, Brindley PJ, Loukas A. Gene discovery for the carcinogenic human liver fluke, Opisthorchis viverrini Bmc Genomics. 8. PMID 17587442 DOI: 10.1186/1471-2164-8-189  0.394
2007 Morales ME, Mann VH, Kines KJ, Gobert GN, Fraser MJ, Kalinna BH, Correnti JM, Pearce EJ, Brindley PJ. piggyBac transposon mediated transgenesis of the human blood fluke, Schistosoma mansoni. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3479-89. PMID 17586730 DOI: 10.1096/Fj.07-8726Com  0.695
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2007 Koehler JW, Morales ME, Shelby BD, Brindley PJ. Aspartic protease activities of schistosomes cleave mammalian hemoglobins in a host-specific manner. MemóRias Do Instituto Oswaldo Cruz. 102: 83-5. PMID 17294005 DOI: 10.1590/S0074-02762007000100014  0.657
2007 Brindley PJ, Pearce EJ. Genetic manipulation of schistosomes. International Journal For Parasitology. 37: 465-73. PMID 17280677 DOI: 10.1016/J.Ijpara.2006.12.012  0.382
2007 Copeland CS, Mann VH, Brindley PJ. Both sense and antisense strands of the LTR of the Schistosoma mansoni Pao-like retrotransposon Sinbad drive luciferase expression. Molecular Genetics and Genomics : Mgg. 277: 161-70. PMID 17131159 DOI: 10.1007/S00438-006-0181-1  0.393
2006 Copeland CS, Lewis FA, Brindley PJ. Identification of the Boudicca and Sinbad retrotransposons in the genome of the human blood fluke Schistosoma haematobium. Memã³Rias Do Instituto Oswaldo Cruz. 101: 565-71. PMID 17072464 DOI: 10.1590/S0074-02762006000500015  0.371
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2006 Gan XX, Shen LY, Wang Y, Ding JZ, Shen HY, Zeng XP, McManus DP, Brindley PJ, Fan J. Recombinant tegumental protein Shistosoma japonicum very lowdensity lipoprotein binding protein as a vaccine candidate against Schistosoma japonicum. Memorias Do Instituto Oswaldo Cruz. 101: 9-13. PMID 16612506 DOI: 10.1590/S0074-02762006000100003  0.301
2006 Kines KJ, Mann VH, Morales ME, Shelby BD, Kalinna BH, Gobert GN, Chirgwin SR, Brindley PJ. Transduction of Schistosoma mansoni by vesicular stomatitis virus glycoprotein-pseudotyped Moloney murine leukemia retrovirus. Experimental Parasitology. 112: 209-20. PMID 16530185 DOI: 10.1016/J.Exppara.2006.02.003  0.665
2006 Laha T, Kewgrai N, Loukas A, Brindley PJ. The dingo non-long terminal repeat retrotransposons from the genome of the hookworm, Ancylostoma caninum. Experimental Parasitology. 113: 142-53. PMID 16445914 DOI: 10.1016/J.Exppara.2005.12.018  0.365
2005 Laha T, Kewgrai N, Loukas A, Brindley PJ. Characterization of SR3 reveals abundance of non-LTR retrotransposons of the RTE clade in the genome of the human blood fluke, Schistosoma mansoni. Bmc Genomics. 6: 154. PMID 16271150 DOI: 10.1186/1471-2164-6-154  0.356
2005 Correnti JM, Brindley PJ, Pearce EJ. Long-term suppression of cathepsin B levels by RNA interference retards schistosome growth. Molecular and Biochemical Parasitology. 143: 209-15. PMID 16076506 DOI: 10.1016/J.Molbiopara.2005.06.007  0.404
2005 Didier ES, Bowers L, Stovall ME, Kuebler D, Mittleider D, Brindley PJ, Didier PJ. Antimicrosporidial activity of (fluoro)quinolones in vitro and in vivo. Folia Parasitologica. 52: 173-81. PMID 16004377 DOI: 10.14411/Fp.2005.022  0.364
2005 Gallego SG, Loukas A, Slade RW, Neva FA, Varatharajalu R, Nutman TB, Brindley PJ. Identification of an astacin-like metallo-proteinase transcript from the infective larvae of Strongyloides stercoralis Parasitology International. 54: 123-133. PMID 15866474 DOI: 10.1016/J.Parint.2005.02.002  0.37
2005 Pandrea I, Mittleider D, Brindley PJ, Didier ES, Robertson DL. Phylogenetic relationships of methionine aminopeptidase 2 among Encephalitozoon species and genotypes of microsporidia. Molecular and Biochemical Parasitology. 140: 141-52. PMID 15760654 DOI: 10.1016/J.Molbiopara.2004.12.006  0.321
2005 Copeland CS, Mann VH, Morales ME, Kalinna BH, Brindley PJ. The Sinbad retrotransposon from the genome of the human blood fluke, Schistosoma mansoni, and the distribution of related Pao-like elements. Bmc Evolutionary Biology. 5: 20. PMID 15725362 DOI: 10.1186/1471-2148-5-20  0.634
2005 Schulmeister A, Heyers O, Morales ME, Brindley PJ, Lucius R, Meusel G, Kalinna BH. Organization and functional analysis of the Schistosoma mansoni cathepsin D-like aspartic protease gene promoter. Biochimica Et Biophysica Acta. 1727: 27-34. PMID 15652155 DOI: 10.1016/J.Bbaexp.2004.11.004  0.657
2005 Clough KA, Drew AC, Brindley PJ. Host-like sequences in the schistosome genome. Parasitology Today (Personal Ed.). 12: 283-6. PMID 15275194 DOI: 10.1016/0169-4758(96)10023-5  0.354
2004 Didier ES, Stovall ME, Green LC, Brindley PJ, Sestak K, Didier PJ. Epidemiology of microsporidiosis: sources and modes of transmission. Veterinary Parasitology. 126: 145-66. PMID 15567583 DOI: 10.1016/J.Vetpar.2004.09.006  0.352
2004 Laha T, Loukas A, Smyth DJ, Copeland CS, Brindley PJ. The fugitive LTR retrotransposon from the genome of the human blood fluke, Schistosoma mansoni. International Journal For Parasitology. 34: 1365-75. PMID 15542097 DOI: 10.1016/J.Ijpara.2004.08.007  0.367
2004 Morales ME, Kalinna BH, Heyers O, Mann VH, Schulmeister A, Copeland CS, Loukas A, Brindley PJ. Genomic organization of the Schistosoma mansoni aspartic protease gene, a platyhelminth orthologue of mammalian lysosomal cathepsin D. Gene. 338: 99-109. PMID 15302411 DOI: 10.1016/J.Gene.2004.05.017  0.671
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2004 McCarthy E, Stack C, Donnelly SM, Doyle S, Mann VH, Brindley PJ, Stewart M, Day TA, Maule AG, Dalton JP. Leucine aminopeptidase of the human blood flukes, Schistosoma mansoni and Schistosoma japonicum International Journal For Parasitology. 34: 703-714. PMID 15111092 DOI: 10.1016/J.Ijpara.2004.01.008  0.321
2004 Copeland CS, Heyers O, Kalinna BH, Bachmair A, Stadler PF, Hofacker IL, Brindley PJ. Structural and evolutionary analysis of the transcribed sequence of Boudicca, a Schistosoma mansoni retrotransposon. Gene. 329: 103-14. PMID 15033533 DOI: 10.1016/J.Gene.2003.12.023  0.369
2003 Heyers O, Walduck AK, Brindley PJ, Bleiß W, Lucius R, Dorbic T, Wittig B, Kalinna BH. Schistosoma mansoni miracidia transformed by particle bombardment infect Biomphalaria glabrata snails and develop into transgenic sporocysts Experimental Parasitology. 105: 174-178. PMID 14969695 DOI: 10.1016/J.Exppara.2003.11.001  0.341
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2003 Williamson AL, Brindley PJ, Knox DP, Hotez PJ, Loukas A. Digestive proteases of blood-feeding nematodes. Trends in Parasitology. 19: 417-23. PMID 12957519 DOI: 10.1016/S1471-4922(03)00189-2  0.364
2003 Dalton JP, Brindley PJ, Knox DP, Brady CP, Hotez PJ, Donnelly S, O'Neill SM, Mulcahy G, Loukas A. Helminth vaccines: from mining genomic information for vaccine targets to systems used for protein expression. International Journal For Parasitology. 33: 621-40. PMID 12782060 DOI: 10.1016/S0020-7519(03)00057-2  0.355
2003 Copeland CS, Brindley PJ, Heyers O, Michael SF, Johnston DA, Williams DL, Ivens AC, Kalinna BH. Boudicca, a retrovirus-like long terminal repeat retrotransposon from the genome of the human blood fluke Schistosoma mansoni. Journal of Virology. 77: 6153-66. PMID 12743272 DOI: 10.1128/Jvi.77.11.6153-6166.2003  0.396
2003 Williamson AL, Brindley PJ, Loukas A. Hookworm cathepsin D aspartic proteases: Contributing roles in the host-specific degradation of serum proteins and skin macromolecules Parasitology. 126: 179-185. PMID 12636356 DOI: 10.1017/S0031182002002706  0.361
2003 Brindley PJ, Laha T, McManus DP, Loukas A. Mobile genetic elements colonizing the genomes of metazoan parasites. Trends in Parasitology. 19: 79-87. PMID 12586476 DOI: 10.1016/S1471-4922(02)00061-2  0.385
2003 Williamson AL, Brindley PJ, Abbenante G, Datu BJ, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Zhan B, Loukas A. Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion. The Journal of Infectious Diseases. 187: 484-94. PMID 12552433 DOI: 10.1086/367708  0.312
2002 Mittleider D, Green LC, Mann VH, Michael SF, Didier ES, Brindley PJ. Sequence survey of the genome of the opportunistic microsporidian pathogen, Vittaforma corneae. The Journal of Eukaryotic Microbiology. 49: 393-401. PMID 12425527 DOI: 10.1111/J.1550-7408.2002.Tb00218.X  0.347
2002 Williamson AL, Brindley PJ, Abbenante G, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Dalton JP, Loukas A. Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1458-60. PMID 12205047 DOI: 10.1096/Fj.02-0181Fje  0.367
2002 Laha T, Brindley PJ, Smout MJ, Verity CK, McManus DP, Loukas A. Reverse transcriptase activity and untranslated region sharing of a new RTE-like, non-long terminal repeat retrotransposon from the human blood fluke, Schistosoma japonicum. International Journal For Parasitology. 32: 1163-74. PMID 12117499 DOI: 10.1016/S0020-7519(02)00063-2  0.362
2002 Laha T, Brindley PJ, Verity CK, McManus DP, Loukas A. pido, a non-long terminal repeat retrotransposon of the chicken repeat 1 family from the genome of the Oriental blood fluke, Schistosoma japonicum. Gene. 284: 149-59. PMID 11891056 DOI: 10.1016/S0378-1119(02)00381-5  0.385
2001 Brinkworth RI, Prociv P, Loukas A, Brindley PJ. Hemoglobin-degrading, aspartic proteases of blood-feeding parasites: substrate specificity revealed by homology models. The Journal of Biological Chemistry. 276: 38844-51. PMID 11495896 DOI: 10.1074/Jbc.M101934200  0.348
2001 Bogitsh BJ, Dalton JP, Brady CP, Brindley PJ. Gut-associated immunolocalization of the Schistosoma mansoni cysteine proteases, SmCL1 and SmCL2. The Journal of Parasitology. 87: 237-41. PMID 11318550 DOI: 10.1645/0022-3395(2001)087[0237:Gaiots]2.0.Co;2  0.325
2001 Verity CK, Loukas A, McManus DP, Brindley PJ. Schistosoma japonicum cathepsin D aspartic protease cleaves human IgG and other serum components. Parasitology. 122: 415-21. PMID 11315174 DOI: 10.1017/S0031182001007521  0.301
2001 Laha T, Loukas A, Verity CK, McManus DP, Brindley PJ. Gulliver, a long terminal repeat retrotransposon from the genome of the oriental blood fluke Schistosoma japonicum. Gene. 264: 59-68. PMID 11245979 DOI: 10.1016/S0378-1119(00)00601-6  0.377
2000 Loukas A, Dowd AJ, Prociv P, Brindley PJ. Purification of a diagnostic, secreted cysteine protease-like protein from the hookworm Ancylostoma caninum. Parasitology International. 49: 327-33. PMID 11077267 DOI: 10.1016/S1383-5769(00)00054-4  0.31
2000 Laha T, McManus DP, Loukas A, Brindley PJ. Sjalpha elements, short interspersed element-like retroposons bearing a hammerhead ribozyme motif from the genome of the oriental blood fluke Schistosoma japonicum. Biochimica Et Biophysica Acta. 1492: 477-82. PMID 11004517 DOI: 10.1016/S0167-4781(00)00112-3  0.353
2000 Hola-Jamriska L, King LT, Dalton JP, Mann VH, Aaskov JG, Brindley PJ. Functional expression of dipeptidyl peptidase I (Cathepsin C) of the oriental blood fluke Schistosoma japonicum in Trichoplusia ni insect cells. Protein Expression and Purification. 19: 384-92. PMID 10910729 DOI: 10.1006/Prep.2000.1261  0.311
2000 Brinkworth RI, Harrop SA, Prociv P, Brindley PJ. Host specificity in blood feeding parasites: a defining contribution by haemoglobin-degrading enzymes? International Journal For Parasitology. 30: 785-90. PMID 10856514 DOI: 10.1016/S0020-7519(00)00045-X  0.351
2000 Brady CP, Brindley PJ, Dowd AJ, Dalton JP. Schistosoma mansoni: differential expression of cathepsins L1 and L2 suggests discrete biological functions for each enzyme. Experimental Parasitology. 94: 75-83. PMID 10673343 DOI: 10.1006/Expr.1999.4478  0.316
2000 Verity CK, McManus DP, Brindley PJ. Developmental expression of cathepsin D aspartic protease in Schistosoma japonicum. International Journal For Parasitology. 29: 1819-24. PMID 10616928 DOI: 10.1016/S0020-7519(99)00126-5  0.355
2000 Sun W, Liu S, Brindley PJ, McManus DP. Bacterial expression and characterization of functional recombinant triosephosphate isomerase from Schistosoma japonicum. Protein Expression and Purification. 17: 410-3. PMID 10600459 DOI: 10.1006/Prep.1999.1140  0.302
1999 Brady CP, Dowd AJ, Tort J, Roche L, Condon B, O'Neill SM, Brindley PJ, Dalton JP. The cathepsin L-like proteinases of liver fluke and blood fluke parasites of the trematode genera Fasciola and Schistosoma Biochemical Society Transactions. 27: 740-745. PMID 10917675 DOI: 10.1042/Bst0270740  0.304
1999 Drew AC, Minchella DJ, King LT, Rollinson D, Brindley PJ. SR2 elements, non-long terminal repeat retrotransposons of the RTE-1 lineage from the human blood fluke Schistosoma mansoni. Molecular Biology and Evolution. 16: 1256-69. PMID 10486981 DOI: 10.1093/Oxfordjournals.Molbev.A026216  0.301
1999 Williams SA, Johnston DA, Aslett M, Bierwert L, Blaxter ML, Daub J, Foster J, Ganatra M, Guiliano D, Haynes S, Jayaraman K, Kamal IH, Kannan K, Laney SJ, Li W, ... ... Brindley P, et al. Helminth genome analysis: The current status of the filarial and schistosome genome projects Parasitology. 118: S19-S38. PMID 10466135 DOI: 10.1017/S0031182099004473  0.385
1999 Tort J, Brindley PJ, Knox D, Wolfe KH, Dalton JP. Proteinases and associated genes of parasitic helminths. Advances in Parasitology. 43: 161-266. PMID 10214692 DOI: 10.1016/S0065-308X(08)60243-2  0.391
1999 Brady CP, Dowd AJ, Brindley PJ, Ryan T, Day SR, Dalton JP. Recombinant expression and localization of Schistosoma mansoni cathepsin L1 support its role in the degradation of host hemoglobin. Infection and Immunity. 67: 368-74. PMID 9864238 DOI: 10.1128/Iai.67.1.368-374.1999  0.337
1998 Fan J, Minchella DJ, Day SR, McManus DP, Tiu WU, Brindley PJ. Generation, identification, and evaluation of expressed sequence tags from different developmental stages of the Asian blood fluke Schistosoma japonicum Biochemical and Biophysical Research Communications. 252: 348-356. PMID 9826533 DOI: 10.1006/Bbrc.1998.9491  0.404
1998 Gallego SG, Slade RW, Brindley PJ. A cDNA encoding a pepsinogen-like, aspartic protease from the human roundworm parasite Strongyloides stercoralis. Acta Tropica. 71: 17-26. PMID 9776140 DOI: 10.1016/S0001-706X(98)00050-3  0.369
1998 Fan J, Brindley PJ. Characterization of cDNAs encoding a new family of tetraspanins from schistosomes--the Sj25 family. Gene. 219: 1-8. PMID 9756983 DOI: 10.1016/S0378-1119(98)00397-7  0.336
1998 Hola-Jamriska L, Tort JF, Dalton JP, Day SR, Fan J, Aaskov J, Brindley PJ. Cathepsin C from Schistosoma japonicum--cDNA encoding the preproenzyme and its phylogenetic relationships. European Journal of Biochemistry. 255: 527-34. PMID 9738890 DOI: 10.1046/J.1432-1327.1998.2550527.X  0.308
1998 Drew AC, Brindley PJ, Lewis FA, Liang YS, Minchella DJ. Tandemly repeated genomic sequence demonstrates inter- and intra-strain genetic variation in Schistosoma japonicum Tropical Medicine and International Health. 3: 373-380. PMID 9623942 DOI: 10.1046/J.1365-3156.1998.00228.X  0.309
1997 Fan J, Hooker CW, McManus DP, Brindley PJ. A new member of the transmembrane 4 superfamily (TM4SF) of proteins from schistosomes, expressed by larval and adult Schistosoma japonicum. Biochimica Et Biophysica Acta. 1329: 18-25. PMID 9370241 DOI: 10.1016/S0005-2736(97)00147-8  0.355
1997 Brindley PJ, Kalinna BH, Dalton JP, Day SR, Wong JY, Smythe ML, McManus DP. Proteolytic degradation of host hemoglobin by schistosomes. Molecular and Biochemical Parasitology. 89: 1-9. PMID 9297696 DOI: 10.1016/S1383-5769(98)80112-8  0.378
1997 Dalton JP, Day SR, Drew AC, Brindley PJ. A method for the isolation of schistosome eggs and miracidia free of contaminating host tissues. Parasitology. 29-32. PMID 9226954 DOI: 10.1017/S0031182097001091  0.333
1997 Drew AC, Brindley PJ. A retrotransposon of the non-long terminal repeat class from the human blood fluke Schistosoma mansoni. Similarities to the chicken-repeat-1-like elements of vertebrates. Molecular Biology and Evolution. 14: 602-10. PMID 9190061 DOI: 10.1093/Oxfordjournals.Molbev.A025799  0.31
1997 Wong JY, Harrop SA, Day SR, Brindley PJ. Schistosomes express two forms of cathepsin D. Biochimica Et Biophysica Acta. 1338: 156-60. PMID 9128134 DOI: 10.1016/S0167-4838(97)00019-8  0.301
1997 Brinkworth RI, Brindley PJ, Harrop SA. Structural analysis of the catalytic site of AcCP-1, a cysteine proteinase secreted by the hookworm Ancylostoma caninum. Biochimica Et Biophysica Acta. 1298: 4-8. PMID 8948483 DOI: 10.1016/S0167-4838(96)00150-1  0.312
1996 Harrop SA, Prociv P, Brindley PJ. Acasp, a gene encoding a cathepsin D-like aspartic protease from the hookworm Ancylostoma caninum. Biochemical and Biophysical Research Communications. 227: 294-302. PMID 8858139 DOI: 10.1006/Bbrc.1996.1503  0.317
1996 Dalton JP, Hola-Jamriska L, Brindley PJ. Asparaginyl endopeptidase activity in adult Schistosoma mansoni. Parasitology. 575-80. PMID 8559590 DOI: 10.1017/S0031182000077052  0.306
1996 Brindley PJ, McManus DP. The pig as a unique host model for Schistosoma japonicum infection: Reply Parasitology Today. 12: 164. DOI: 10.1016/0169-4758(96)80807-6  0.319
1995 Hooker CW, Yang W, Becker MM, Waine GJ, Kalinna BH, Nimmo KA, McManus DP, Brindley PJ. Schistosoma japonicum: heterogeneity in paramyosin genes. Acta Tropica. 59: 131-41. PMID 7676904 DOI: 10.1016/0001-706X(94)00089-J  0.341
1995 Becker MM, Harrop SA, Dalton JP, Kalinna BH, McManus DP, Brindley PJ. Cloning and characterization of the Schistosoma japonicum aspartic proteinase involved in hemoglobin degradation. The Journal of Biological Chemistry. 270: 24496-501. PMID 7592666 DOI: 10.1074/Jbc.270.41.24496  0.357
1995 Brindley PJ, Gam AA, McKerrow JH, Neva FA. Ss40: the zinc endopeptidase secreted by infective larvae of Strongyloides stercoralis. Experimental Parasitology. 80: 1-7. PMID 7529715 DOI: 10.1006/Expr.1995.1001  0.334
1995 Drew AC, Brindley PJ. Female-specific sequences isolated from Schistosoma mansoni by representational difference analysis. Molecular and Biochemical Parasitology. 71: 173-81. PMID 7477099 DOI: 10.1016/0166-6851(95)00048-6  0.326
1995 Harrop SA, Sawangjaroen N, Prociv P, Brindley PJ. Characterization and localization of cathepsin B proteinases expressed by adult Ancylostoma caninum hookworms. Molecular and Biochemical Parasitology. 71: 163-71. PMID 7477098 DOI: 10.1016/0166-6851(95)00045-3  0.35
1995 Dalton JP, Smith AM, Clough KA, Brindley PJ. Digestion of haemoglobin by schistosomes: 35 years on Parasitology Today. 11: 299-303. DOI: 10.1016/0169-4758(95)80045-X  0.311
1994 Brindley PJ. Relationships between chemotherapy and immunity in schistosomiasis. Advances in Parasitology. 34: 133-61. PMID 7976749 DOI: 10.1016/S0065-308X(08)60138-4  0.329
1994 Dowd AJ, Dalton JP, Loukas AC, Prociv P, Brindley PJ. Secretion of cysteine proteinase activity by the zoonotic hookworm Ancylostoma caninum. The American Journal of Tropical Medicine and Hygiene. 51: 341-7. PMID 7943555 DOI: 10.4269/Ajtmh.1994.51.341  0.317
1994 Ellis J, Luton K, Baverstock PR, Brindley PJ, Nimmo KA, Johnson AM. The phylogeny of Neospora caninum. Molecular and Biochemical Parasitology. 64: 303-11. PMID 7935608 DOI: 10.1016/0166-6851(94)00033-6  0.345
1994 Smith AM, Dalton JP, Clough KA, Kilbane CL, Harrop SA, Hole N, Brindley PJ. Adult Schistosoma mansoni express cathepsin L proteinase activity Molecular and Biochemical Parasitology. 67: 11-19. PMID 7838171 DOI: 10.1016/0166-6851(94)90091-4  0.322
1991 Knight M, Brindley PJ, Richards CS, Lewis FA. Schistosoma mansoni: use of a cloned ribosomal RNA gene probe to detect restriction fragment length polymorphisms in the intermediate host Biomphalaria glabrata. Experimental Parasitology. 73: 285-94. PMID 1680745 DOI: 10.1016/0014-4894(91)90100-B  0.351
1991 Brindley PJ, Heath S, Waters AP, McCutchan TF, Sher A. Characterization of a programmed alteration in an 18S ribosomal gene that accompanies the experimental induction of drug resistance in Schistosoma mansoni. Proceedings of the National Academy of Sciences of the United States of America. 88: 7754-8. PMID 1679236 DOI: 10.1073/Pnas.88.17.7754  0.351
1991 Vieira LQ, Correa-Oliveira R, Katz N, de Souza CP, Carvalho OS, Araujo N, Sher A, Brindley PJ. Genomic variability in field populations of Schistosoma mansoni in Brazil as detected with a ribosomal gene probe. The American Journal of Tropical Medicine and Hygiene. 44: 69-78. PMID 1671740 DOI: 10.4269/Ajtmh.1991.44.69  0.339
1990 McKerrow JH, Brindley P, Brown M, Gam AA, Staunton C, Neva FA. Strongyloides stercoralis: identification of a protease that facilitates penetration of skin by the infective larvae. Experimental Parasitology. 70: 134-43. PMID 2137091 DOI: 10.1016/0014-4894(90)90094-S  0.343
1989 Brindley PJ, Lewis FA, McCutchan TF, Bueding E, Sher A. A genomic change associated with the development of resistance to hycanthone in Schistosoma mansoni. Molecular and Biochemical Parasitology. 36: 243-52. PMID 2571929 DOI: 10.1016/0166-6851(89)90172-2  0.318
1987 Prociv P, Brindley PJ. Oral, parenteral and paratenic infections of mice with Toxocara pteropodis. International Journal For Parasitology. 16: 471-4. PMID 3781731 DOI: 10.1016/0020-7519(86)90082-2  0.327
1987 Brindley PJ, Sher A. Anti-schistosomal drugs: observations on the mechanism of drug resistance to hycanthone, and on the involvement of host antibodies in the mode of action of praziquantel Memorias Do Instituto Oswaldo Cruz. 82: 157-161. PMID 3151089 DOI: 10.1590/S0074-02761987000800027  0.301
1985 Dobson C, Sitepu P, Brindley PJ. Influence of primary infection on the population dynamics of Nematospiroides dubius after challenge infections in mice International Journal For Parasitology. 15: 353-359. PMID 4030209 DOI: 10.1016/0020-7519(85)90019-0  0.301
1983 Brindley PJ, Dobson C. Specificity of passive serum protection against Nippostrongylus brasiliensis and Nematospiroides dubius in mice Australian Journal of Experimental Biology and Medical Science. 61: 37-45. PMID 6870676 DOI: 10.1038/Icb.1983.4  0.302
1982 Brindley PJ, Dobson C. Multiple infections with Nematospiroides dubius in mice selected for liability to a single infection The Australian Journal of Experimental Biology and Medical Science. 60: 319-327. PMID 7138418 DOI: 10.1038/Icb.1982.35  0.307
1982 Brindley PJ, Dobson C. Nematospiroides dubius in mice selected for liability to infection: Modification of parasite biology through host selection International Journal For Parasitology. 12: 573-578. DOI: 10.1016/0020-7519(82)90054-6  0.306
1981 Brindley PJ, Dobson C. Genetic control of liability to infection with Nematospiroides dubius in mice: Selection of refractory and liable populations of mice Parasitology. 83: 51-65. PMID 7196567 DOI: 10.1017/S0031182000050034  0.323
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