| Year |
Citation |
Score |
| 2021 |
Yan Y, Krecke KN, Bapat AS, Yang T, Lopresti MW, Mashek DG, Kelekar A. Phosphatase PHLPP2 regulates the cellular response to metabolic stress through AMPK. Cell Death & Disease. 12: 904. PMID 34608126 DOI: 10.1038/s41419-021-04196-4 |
0.365 |
|
| 2021 |
Jemmerson R, Staskus K, Higgins L, Conklin K, Kelekar A. Intracellular leucine-rich alpha-2-glycoprotein-1 competes with Apaf-1 for binding cytochrome c in protecting MCF-7 breast cancer cells from apoptosis. Apoptosis : An International Journal On Programmed Cell Death. PMID 33386492 DOI: 10.1007/s10495-020-01647-9 |
0.331 |
|
| 2018 |
McDonald-Hyman C, Muller JT, Loschi M, Thangavelu G, Saha A, Kumari S, Reichenbach DK, Smith MJ, Zhang G, Koehn BH, Lin J, Mitchell JS, Fife BT, Panoskaltsis-Mortari A, Feser CJ, ... ... Kelekar A, et al. The vimentin intermediate filament network restrains regulatory T-cell suppression of graft-versus-host disease. The Journal of Clinical Investigation. PMID 30106752 DOI: 10.1172/Jci95713 |
0.344 |
|
| 2017 |
Guo Z, Sevrioukova IF, Denisov IG, Zhang X, Chiu TL, Thomas DG, Hanse EA, Cuellar RAD, Grinkova YV, Langenfeld VW, Swedien DS, Stamschror JD, Alvarez J, Luna F, Galván A, ... ... Kelekar A, et al. Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. Cell Chemical Biology. 24: 1314. PMID 29053951 DOI: 10.1016/J.Chembiol.2017.09.012 |
0.332 |
|
| 2017 |
Guo Z, Sevrioukova IF, Denisov IG, Zhang X, Chiu TL, Thomas DG, Hanse EA, Cuellar RAD, Grinkova YV, Langenfeld VW, Swedien DS, Stamschror JD, Alvarez J, Luna F, Galván A, ... ... Kelekar A, et al. Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. Cell Chemical Biology. PMID 28919040 DOI: 10.1016/J.Chembiol.2017.08.009 |
0.396 |
|
| 2017 |
Hippen KL, O'Connor RS, Lemire AM, Saha A, Hanse EA, Tennis NC, Merkel SC, Kelekar A, Riley JL, Levine BL, June CH, Kean LS, MacMillan ML, Miller JS, Wagner JE, et al. In vitro induction of human regulatory T-cells (iTregs) using conditions of low tryptophan plus kynurenines. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28470889 DOI: 10.1182/Blood.V128.22.1229.1229 |
0.337 |
|
| 2017 |
Hanse EA, Ruan C, Kachman M, Wang D, Lowman XH, Kelekar A. Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer. Oncogene. PMID 28263970 DOI: 10.1038/Onc.2017.36 |
0.683 |
|
| 2016 |
Yan Y, Hanse EA, Stedman K, Benson JM, Lowman XH, Subramanian S, Kelekar A. Transcription factor C/EBP-β induces tumor-suppressor phosphatase PHLPP2 through repression of the miR-17-92 cluster in differentiating AML cells. Cell Death and Differentiation. PMID 26868909 DOI: 10.1038/Cdd.2016.1 |
0.657 |
|
| 2016 |
Guo Z, Sevrioukova I, Hanse E, Zhang X, Denisov I, Chiu T, Cuellar R, Torres C, Wulfkuhle J, Petricoin E, Cao Q, Chu H, Norris B, Schumacher R, Kelekar A, et al. Abstract 44: Hexyl-benzyl-biguanide (HBB) potently and selectively inhibits CYP3A4 epoxygenase activity and inhibits EET stabilization of mitochondrial respiration in ER+HER2- breast cancer cells, inducing glycolysis and pyruvate biosynthesis Cancer Research. 76: 44-44. DOI: 10.1158/1538-7445.Am2016-44 |
0.412 |
|
| 2015 |
Karim CB, Michel Espinoza-Fonseca L, James ZM, Hanse EA, Gaynes JS, Thomas DD, Kelekar A. Erratum: Structural Mechanism for Regulation of Bcl-2 protein Noxa by phosphorylation. Scientific Reports. 5: 15872. PMID 26513659 DOI: 10.1038/Srep15872 |
0.318 |
|
| 2015 |
Karim CB, Michel Espinoza-Fonseca L, James ZM, Hanse EA, Gaynes JS, Thomas DD, Kelekar A. Structural Mechanism for Regulation of Bcl-2 protein Noxa by phosphorylation. Scientific Reports. 5: 14557. PMID 26411306 DOI: 10.1038/Srep14557 |
0.316 |
|
| 2015 |
McDonald-Hyman C, Thangavelu G, Muller J, Zhang G, Kumari S, Saha A, Koehn BH, Mitchell JS, Fife BT, Serody JS, Osborn MJ, Hippen KL, Kelekar A, Munn DH, Altman A, et al. Protein Kinase C-Theta Interacts with mTORC2 and Vimentin to Limit Regulatory T-Cell Function Blood. 126: 849-849. DOI: 10.1182/Blood.V126.23.849.849 |
0.377 |
|
| 2015 |
Gaynes JS, Hanse EA, Kelekar A. Abstract 3043: Discovery of a novel mitochondrial protein complex containing pro-apoptotic Noxa in leukemia Cancer Research. 75: 3043-3043. DOI: 10.1158/1538-7445.Am2015-3043 |
0.36 |
|
| 2014 |
Guo Z, Chavez KJ, Alvarez J, Zhang X, Norris B, Maher M, Morgan M, Schumacher RJ, Cuellar R, Sevrioukova IF, Poulos TL, Denisov I, Sligar SG, Gupta K, Blair IA, ... ... Kelekar A, et al. Abstract 2689: Breast cancer inhibition by a novel and potent biguanide, N1-hexyl-N5-benzyl-biguanide Cancer Research. 74: 2689-2689. DOI: 10.1158/1538-7445.Am2014-2689 |
0.336 |
|
| 2013 |
Das SG, Hermanson DL, Bleeker N, Lowman X, Li Y, Kelekar A, Xing C. Ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017): a novel scaffold that resensitizes multidrug resistant leukemia cells to chemotherapy. Acs Chemical Biology. 8: 327-35. PMID 23102022 DOI: 10.1021/Cb300460F |
0.672 |
|
| 2011 |
Sanchez CG, Penfornis P, Oskowitz AZ, Boonjindasup AG, Cai DZ, Dhule SS, Rowan BG, Kelekar A, Krause DS, Pochampally RR. Activation of autophagy in mesenchymal stem cells provides tumor stromal support. Carcinogenesis. 32: 964-72. PMID 21317300 DOI: 10.1093/Carcin/Bgr029 |
0.406 |
|
| 2010 |
Lowman XH, McDonnell MA, Kosloske A, Odumade OA, Jenness C, Karim CB, Jemmerson R, Kelekar A. The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose. Molecular Cell. 40: 823-33. PMID 21145489 DOI: 10.1016/J.Molcel.2010.11.035 |
0.682 |
|
| 2010 |
Separovic D, Kelekar A, Nayak AK, Tarca AL, Hanada K, Pierce JS, Bielawski J. Increased ceramide accumulation correlates with downregulation of the autophagy protein ATG-7 in MCF-7 cells sensitized to photodamage. Archives of Biochemistry and Biophysics. 494: 101-5. PMID 19944062 DOI: 10.1016/J.Abb.2009.11.023 |
0.399 |
|
| 2010 |
Codina R, Vanasse A, Kelekar A, Vezys V, Jemmerson R. Cytochrome c-induced lymphocyte death from the outside in: inhibition by serum leucine-rich alpha-2-glycoprotein-1. Apoptosis : An International Journal On Programmed Cell Death. 15: 139-52. PMID 19851871 DOI: 10.1007/S10495-009-0412-0 |
0.317 |
|
| 2009 |
Nguyen TM, Subramanian IV, Xiao X, Ghosh G, Nguyen P, Kelekar A, Ramakrishnan S. Endostatin induces autophagy in endothelial cells by modulating Beclin 1 and beta-catenin levels. Journal of Cellular and Molecular Medicine. 13: 3687-98. PMID 19298526 DOI: 10.1111/J.1582-4934.2009.00722.X |
0.384 |
|
| 2008 |
Kelekar A. Introduction to the Review Series Autophagy in Higher Eukaryotes- A matter of survival or death. Autophagy. 4: 555-556. PMID 28186853 DOI: 10.4161/Auto.6396 |
0.36 |
|
| 2008 |
McDonnell MA, Abedin MJ, Melendez M, Platikanova TN, Ecklund JR, Ahmed K, Kelekar A. Phosphorylation of murine caspase-9 by the protein kinase casein kinase 2 regulates its cleavage by caspase-8. The Journal of Biological Chemistry. 283: 20149-58. PMID 18467326 DOI: 10.1074/Jbc.M802846200 |
0.368 |
|
| 2007 |
Ramakrishnan S, Nguyen TM, Subramanian IV, Kelekar A. Autophagy and angiogenesis inhibition. Autophagy. 3: 512-5. PMID 17643071 DOI: 10.4161/Auto.4734 |
0.383 |
|
| 2007 |
Zhao Y, Altman BJ, Coloff JL, Herman CE, Jacobs SR, Wieman HL, Wofford JA, Dimascio LN, Ilkayeva O, Kelekar A, Reya T, Rathmell JC. Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. Molecular and Cellular Biology. 27: 4328-39. PMID 17371841 DOI: 10.1128/Mcb.00153-07 |
0.436 |
|
| 2007 |
Nguyen TM, Subramanian IV, Kelekar A, Ramakrishnan S. Kringle 5 of human plasminogen, an angiogenesis inhibitor, induces both autophagy and apoptotic death in endothelial cells. Blood. 109: 4793-802. PMID 17272502 DOI: 10.1182/Blood-2006-11-059352 |
0.363 |
|
| 2007 |
Abedin MJ, Wang D, McDonnell MA, Lehmann U, Kelekar A. Autophagy delays apoptotic death in breast cancer cells following DNA damage. Cell Death and Differentiation. 14: 500-10. PMID 16990848 DOI: 10.1038/Sj.Cdd.4402039 |
0.4 |
|
| 2005 |
Wang D, McDonnell MA, Kelekar A. Multi-probe RPA template sets to study RNA modulation and transcriptional control of BH3-only members of the Bcl-2 family. Cancer Detection and Prevention. 29: 189-200. PMID 15829380 DOI: 10.1016/J.Cdp.2004.12.002 |
0.385 |
|
| 2004 |
Ke H, Pei J, Ni Z, Xia H, Qi H, Woods T, Kelekar A, Tao W. Putative tumor suppressor Lats2 induces apoptosis through downregulation of Bcl-2 and Bcl-x(L). Experimental Cell Research. 298: 329-38. PMID 15265683 DOI: 10.1016/J.Yexcr.2004.04.031 |
0.426 |
|
| 2003 |
Vallera DA, Jin N, Shu Y, Panoskaltsis-Mortari A, Kelekar A, Chen W. Retroviral immunotoxin gene therapy of leukemia in mice using leukemia-specific T cells transduced with an interleukin-3/Bax fusion protein gene. Human Gene Therapy. 14: 1787-98. PMID 14670129 DOI: 10.1089/104303403322611791 |
0.353 |
|
| 2003 |
McDonnell MA, Wang D, Khan SM, Vander Heiden MG, Kelekar A. Caspase-9 is activated in a cytochrome c-independent manner early during TNFα-induced apoptosis in murine cells Cell Death and Differentiation. 10: 1005-1015. PMID 12934075 DOI: 10.1038/Sj.Cdd.4401271 |
0.374 |
|
| 2001 |
Kaspar AA, Okada S, Kumar J, Poulain FR, Drouvalakis KA, Kelekar A, Hanson DA, Kluck RM, Hitoshi Y, Johnson DE, Froelich CJ, Thompson CB, Newmeyer DD, Anel A, Clayberger C, et al. A distinct pathway of cell-mediated apoptosis initiated by granulysin. Journal of Immunology (Baltimore, Md. : 1950). 167: 350-6. PMID 11418670 DOI: 10.4049/Jimmunol.167.1.350 |
0.396 |
|
| 1999 |
Chang BS, Kelekar A, Harris MH, Harlan JE, Fesik SW, Thompson CB. The BH3 domain of Bcl-x(S) is required for inhibition of the antiapoptotic function of Bcl-x(L). Molecular and Cellular Biology. 19: 6673-81. PMID 10490606 DOI: 10.1128/Mcb.19.10.6673 |
0.315 |
|
| 1999 |
Pena JC, Kelekar A, Fuchs EV, Thompson CB. Manipulation of outer root sheath cell survival perturbs the hair-growth cycle. The Embo Journal. 18: 3596-603. PMID 10393176 DOI: 10.1093/Emboj/18.13.3596 |
0.359 |
|
| 1999 |
Minn AJ, Kettlun CS, Liang H, Kelekar A, Vander Heiden MG, Chang BS, Fesik SW, Fill M, Thompson CB. Bcl-x(L) regulates apoptosis by heterodimerization-dependent and -independent mechanisms Embo Journal. 18: 632-643. PMID 9927423 DOI: 10.1093/Emboj/18.3.632 |
0.388 |
|
| 1998 |
Kelekar A, Thompson CB. Bcl-2-family proteins: The role of the BH3 domain in apoptosis Trends in Cell Biology. 8: 324-330. PMID 9704409 DOI: 10.1016/S0962-8924(98)01321-X |
0.338 |
|
| 1997 |
Kelekar A, Chang BS, Harlan JE, Fesik SW, Thompson CB. Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL Molecular and Cellular Biology. 17: 7040-7046. PMID 9372935 DOI: 10.1128/Mcb.17.12.7040 |
0.395 |
|
| 1987 |
Kelekar A, Cole MD. Immortalization by c-myc, H-ras, and Ela oncogenes induces differential cellular gene expression and growth factor responses. Molecular and Cellular Biology. 7: 3899-907. PMID 2963209 DOI: 10.1128/Mcb.7.11.3899 |
0.307 |
|
| 1986 |
Kelekar A, Cole MD. Tumorigenicity of fibroblast lines expressing the adenovirus E1a, cellular p53, or normal c-myc genes. Molecular and Cellular Biology. 6: 7-14. PMID 2946931 DOI: 10.1128/Mcb.6.1.7 |
0.342 |
|
| 1984 |
Keath EJ, Kelekar A, Cole MD. Transcriptional activation of the translocated c-myc oncogene in mouse plasmacytomas: similar RNA levels in tumor and proliferating normal cells. Cell. 37: 521-8. PMID 6327072 DOI: 10.1016/0092-8674(84)90382-9 |
0.322 |
|
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