| Year |
Citation |
Score |
| 2019 |
Ryba DM, Warren CM, Karam CN, Davis RT, Chowdhury SAK, Alvarez MG, McCann M, Liew CW, Wieczorek DF, Varga P, Solaro RJ, Wolska BM. Sphingosine-1-Phosphate Receptor Modulator, FTY720, Improves Diastolic Dysfunction and Partially Reverses Atrial Remodeling in a Tm-E180G Mouse Model Linked to Hypertrophic Cardiomyopathy. Circulation. Heart Failure. 12: e005835. PMID 31684756 DOI: 10.1161/Circheartfailure.118.005835 |
0.332 |
|
| 2019 |
Schaefer A, Schneeberger Y, Schulz S, Krasemann S, Werner T, Piasecki A, Höppner G, Müller C, Morhenn K, Lorenz K, Wieczorek D, Schwoerer AP, Eschenhagen T, Ehmke H, Reichenspurner H, et al. Analysis of fibrosis in control or pressure overloaded rat hearts after mechanical unloading by heterotopic heart transplantation. Scientific Reports. 9: 5710. PMID 30952943 DOI: 10.1038/S41598-019-42263-1 |
0.444 |
|
| 2018 |
Rajan S, Jagatheesan G, Petrashevskaya N, Biesiadecki BJ, Warren CM, Riddle T, Liggett SB, Wolska BM, Solaro RJ, Wieczorek DF. Tropomyosin pseudo-phosphorylation results in dilated cardiomyopathy. The Journal of Biological Chemistry. PMID 30567734 DOI: 10.1074/Jbc.Ra118.004879 |
0.483 |
|
| 2017 |
Alves ML, Warren CM, Simon JN, Gaffin RD, Montminy EM, Wieczorek DF, John Solaro R, Wolska BM. Early Sensitization of Myofilaments to Ca2+ Prevents Genetically Linked Dilated Cardiomyopathy in Mice. Cardiovascular Research. PMID 28379313 DOI: 10.1093/Cvr/Cvx068 |
0.462 |
|
| 2015 |
Wilder T, Ryba DM, Wieczorek DF, Wolska BM, Solaro RJ. N-acetylcysteine reverses diastolic dysfunction and hypertrophy in familial hypertrophic cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 309: H1720-30. PMID 26432840 DOI: 10.1152/Ajpheart.00339.2015 |
0.518 |
|
| 2015 |
Tarigopula M, Davis RT, Mungai PT, Ryba DM, Wieczorek DF, Cowan CL, Violin JD, Wolska BM, Solaro RJ. Cardiac myosin light chain phosphorylation and inotropic effects of a biased ligand, TRV120023, in a dilated cardiomyopathy model. Cardiovascular Research. 107: 226-34. PMID 26045475 DOI: 10.1093/Cvr/Cvv162 |
0.444 |
|
| 2014 |
Prasad V, Lorenz JN, Lasko VM, Nieman ML, Jiang M, Gao X, Rubinstein J, Wieczorek DF, Shull GE. Ablation of plasma membrane Ca(2+)-ATPase isoform 4 prevents development of hypertrophy in a model of hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 77: 53-63. PMID 25280781 DOI: 10.1016/J.Yjmcc.2014.09.025 |
0.552 |
|
| 2014 |
Simon JN, Chowdhury SA, Warren CM, Sadayappan S, Wieczorek DF, Solaro RJ, Wolska BM. Ceramide-mediated depression in cardiomyocyte contractility through PKC activation and modulation of myofilament protein phosphorylation. Basic Research in Cardiology. 109: 445. PMID 25280528 DOI: 10.1007/S00395-014-0445-6 |
0.399 |
|
| 2014 |
Alves ML, Dias FA, Gaffin RD, Simon JN, Montminy EM, Biesiadecki BJ, Hinken AC, Warren CM, Utter MS, Davis RT, Sadayappan S, Robbins J, Wieczorek DF, Solaro RJ, Wolska BM. Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins. Circulation. Cardiovascular Genetics. 7: 132-43. PMID 24585742 DOI: 10.1161/Circgenetics.113.000324 |
0.438 |
|
| 2014 |
Witayavanitkul N, Ait Mou Y, Kuster DW, Khairallah RJ, Sarkey J, Govindan S, Chen X, Ge Y, Rajan S, Wieczorek DF, Irving T, Westfall MV, de Tombe PP, Sadayappan S. Myocardial infarction-induced N-terminal fragment of cardiac myosin-binding protein C (cMyBP-C) impairs myofilament function in human myocardium. The Journal of Biological Chemistry. 289: 8818-27. PMID 24509847 DOI: 10.1074/Jbc.M113.541128 |
0.448 |
|
| 2014 |
Witayavanitkul N, Sarkey J, Aitmou Y, Kuster DW, Khairallah RJ, Govindan S, Chen X, Ge Y, Rajan S, Wieczorek DF, Irving T, de Tombe PP, Sadayappan S. Myocardial Infarction-Induced N-Terminal Fragment of Cmybp-C Impairs Myofilament Function in Human Left Ventricular Myofibrils Biophysical Journal. 106: 347a. DOI: 10.1016/J.Bpj.2013.11.1977 |
0.488 |
|
| 2013 |
Schulz EM, Wilder T, Chowdhury SA, Sheikh HN, Wolska BM, Solaro RJ, Wieczorek DF. Decreasing tropomyosin phosphorylation rescues tropomyosin-induced familial hypertrophic cardiomyopathy. The Journal of Biological Chemistry. 288: 28925-35. PMID 23960072 DOI: 10.1074/Jbc.M113.466466 |
0.708 |
|
| 2013 |
Passariello CL, Gayanilo M, Kritzer MD, Thakur H, Cozacov Z, Rusconi F, Wieczorek D, Sanders M, Li J, Kapiloff MS. p90 ribosomal S6 kinase 3 contributes to cardiac insufficiency in α-tropomyosin Glu180Gly transgenic mice. American Journal of Physiology. Heart and Circulatory Physiology. 305: H1010-9. PMID 23913705 DOI: 10.1152/Ajpheart.00237.2013 |
0.408 |
|
| 2013 |
Rajan S, Pena JR, Jegga AG, Aronow BJ, Wolska BM, Wieczorek DF. Microarray analysis of active cardiac remodeling genes in a familial hypertrophic cardiomyopathy mouse model rescued by a phospholamban knockout. Physiological Genomics. 45: 764-73. PMID 23800848 DOI: 10.1152/Physiolgenomics.00023.2013 |
0.506 |
|
| 2013 |
Schulz EM, Wieczorek DF. Tropomyosin de-phosphorylation in the heart: what are the consequences? Journal of Muscle Research and Cell Motility. 34: 239-46. PMID 23793376 DOI: 10.1007/S10974-013-9348-7 |
0.699 |
|
| 2013 |
Yar S, Chowdhury SA, Davis RT, Kobayashi M, Monasky MM, Rajan S, Wolska BM, Gaponenko V, Kobayashi T, Wieczorek DF, Solaro RJ. Conserved Asp-137 is important for both structure and regulatory functions of cardiac α-tropomyosin (α-TM) in a novel transgenic mouse model expressing α-TM-D137L. The Journal of Biological Chemistry. 288: 16235-46. PMID 23609439 DOI: 10.1074/Jbc.M113.458695 |
0.502 |
|
| 2013 |
Mamidi R, Mallampalli SL, Wieczorek DF, Chandra M. Identification of two new regions in the N-terminus of cardiac troponin T that have divergent effects on cardiac contractile function. The Journal of Physiology. 591: 1217-34. PMID 23207592 DOI: 10.1113/Jphysiol.2012.243394 |
0.518 |
|
| 2013 |
Yar S, Chowdhury SA, Turner M, Rajan S, Wolska BM, Gaponenko V, Debold EP, Kobayashi T, Wieczorek DF, Solaro RJ. Altered Flexibility affects Regulatory Functions of Cardiac α-Tropomyosin (α-Tm) in a Novel Transgenic Mouse Model Expressing α-Tm-D137L Biophysical Journal. 104: 448a. DOI: 10.1016/J.Bpj.2012.11.2485 |
0.523 |
|
| 2013 |
Feng H, Wieczorek DF, Jin J. Additive Compensatory Effects of Cardiac Troponin I and Cardiac Troponin T N-Terminal Truncations on the Disease Phenotypes of a Familial Hypertrophic Cardiomyopathy Mutation (E180G) of α-Tropomyosin Biophysical Journal. 104: 187a. DOI: 10.1016/J.Bpj.2012.11.1057 |
0.542 |
|
| 2012 |
Schulz EM, Correll RN, Sheikh HN, Lofrano-Alves MS, Engel PL, Newman G, Schultz JEJ, Molkentin JD, Wolska BM, Solaro RJ, Wieczorek DF. Tropomyosin dephosphorylation results in compensated cardiac hypertrophy Journal of Biological Chemistry. 287: 44478-44489. PMID 23148217 DOI: 10.1074/Jbc.M112.402040 |
0.739 |
|
| 2012 |
Warren CM, Alves MS, Montminy EM, Simon JN, Gaffin RD, Rajan S, Wieczorek DF, Solaro RJ, Wolska BM. Rescue of a Dilated Cardiomyopathy Mouse Model Caused by a Mutation in Tropomyosin (E54K) by Expression of Slow Skeletal Troponin I Biophysical Journal. 102: 560a. DOI: 10.1016/J.Bpj.2011.11.3051 |
0.541 |
|
| 2011 |
Gaffin RD, Peña JR, Alves MS, Dias FA, Chowdhury SA, Heinrich LS, Goldspink PH, Kranias EG, Wieczorek DF, Wolska BM. Long-term rescue of a familial hypertrophic cardiomyopathy caused by a mutation in the thin filament protein, tropomyosin, via modulation of a calcium cycling protein. Journal of Molecular and Cellular Cardiology. 51: 812-20. PMID 21840315 DOI: 10.1016/J.Yjmcc.2011.07.026 |
0.474 |
|
| 2011 |
Gaffin RD, Chowdhury SA, Alves MS, Dias FA, Ribeiro CT, Fogaca RT, Wieczorek DF, Wolska BM. Effects of nicotine administration in a mouse model of familial hypertrophic cardiomyopathy, α-tropomyosin D175N. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1646-55. PMID 21743000 DOI: 10.1152/Ajpheart.00277.2010 |
0.448 |
|
| 2011 |
Karam CN, Warren CM, Rajan S, de Tombe PP, Wieczorek DF, Solaro RJ. Expression of tropomyosin-κ induces dilated cardiomyopathy and depresses cardiac myofilament tension by mechanisms involving cross-bridge dependent activation and altered tropomyosin phosphorylation. Journal of Muscle Research and Cell Motility. 31: 315-22. PMID 21221740 DOI: 10.1007/S10974-010-9237-2 |
0.559 |
|
| 2011 |
Al Moamen NJ, Prasad V, Bodi I, Miller ML, Neiman ML, Lasko VM, Alper SL, Wieczorek DF, Lorenz JN, Shull GE. Loss of the AE3 anion exchanger in a hypertrophic cardiomyopathy model causes rapid decompensation and heart failure. Journal of Molecular and Cellular Cardiology. 50: 137-46. PMID 21056571 DOI: 10.1016/J.Yjmcc.2010.10.028 |
0.51 |
|
| 2011 |
Sheehan KA, Arteaga GM, Hinken AC, Dias FA, Ribeiro C, Wieczorek DF, Solaro RJ, Wolska BM. Functional effects of a tropomyosin mutation linked to FHC contribute to maladaptation during acidosis. Journal of Molecular and Cellular Cardiology. 50: 442-50. PMID 21047515 DOI: 10.1016/J.Yjmcc.2010.10.032 |
0.504 |
|
| 2010 |
Peña JR, Szkudlarek AC, Warren CM, Heinrich LS, Gaffin RD, Jagatheesan G, del Monte F, Hajjar RJ, Goldspink PH, Solaro RJ, Wieczorek DF, Wolska BM. Neonatal gene transfer of Serca2a delays onset of hypertrophic remodeling and improves function in familial hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 49: 993-1002. PMID 20854827 DOI: 10.1016/J.Yjmcc.2010.09.010 |
0.474 |
|
| 2010 |
Jagatheesan G, Rajan S, Ahmed RP, Petrashevskaya N, Boivin G, Arteaga GM, Tae HJ, Liggett SB, Solaro RJ, Wieczorek DF. Striated muscle tropomyosin isoforms differentially regulate cardiac performance and myofilament calcium sensitivity. Journal of Muscle Research and Cell Motility. 31: 227-39. PMID 20803058 DOI: 10.1007/S10974-010-9228-3 |
0.557 |
|
| 2010 |
Thomas A, Rajan S, Thurston HL, Masineni SN, Dube P, Bose A, Muthu V, Dube S, Wieczorek DF, Poiesz BJ, Dube DK. Expression of a novel tropomyosin isoform in axolotl heart and skeletal muscle. Journal of Cellular Biochemistry. 110: 875-81. PMID 20564186 DOI: 10.1002/Jcb.22599 |
0.53 |
|
| 2010 |
Rajan S, Jagatheesan G, Karam CN, Alves ML, Bodi I, Schwartz A, Bulcao CF, D'Souza KM, Akhter SA, Boivin GP, Dube DK, Petrashevskaya N, Herr AB, Hullin R, Liggett SB, ... ... Wieczorek DF, et al. Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform. Circulation. 121: 410-8. PMID 20065163 DOI: 10.1161/Circulationaha.109.889725 |
0.562 |
|
| 2010 |
Jagatheesan G, Rajan S, Wieczorek DF. Investigations into tropomyosin function using mouse models. Journal of Molecular and Cellular Cardiology. 48: 893-8. PMID 19835881 DOI: 10.1016/J.Yjmcc.2009.10.003 |
0.529 |
|
| 2010 |
Karam C, Alves M, Wolsa BM, Rajan S, Wieczorek DF, Solaro RJ. Tropomyosin-Kappa Alters Cardiac Dynamics in a Mouse Heart Model Biophysical Journal. 98: 358a-359a. DOI: 10.1016/J.Bpj.2009.12.1935 |
0.58 |
|
| 2010 |
Biesiadecki BJ, Alves ML, Jagatheesan G, Liu B, Scellini B, Tesi C, Davis JP, Poggesi C, Wieczorek DF, Wolska BM, Solaro RJ. Tropomyosin Pseudo-Phosphorylation and Muscle Kinetics Biophysical Journal. 98: 350a. DOI: 10.1016/J.Bpj.2009.12.1893 |
0.554 |
|
| 2009 |
Jagatheesan G, Rajan S, Schulz EM, Ahmed RP, Petrashevskaya N, Schwartz A, Boivin GP, Arteaga GM, Wang T, Wang YG, Ashraf M, Liggett SB, Lorenz J, Solaro RJ, Wieczorek DF. An internal domain of beta-tropomyosin increases myofilament Ca(2+) sensitivity. American Journal of Physiology. Heart and Circulatory Physiology. 297: H181-90. PMID 19429821 DOI: 10.1152/Ajpheart.00329.2008 |
0.771 |
|
| 2009 |
Jagatheesan G, Schulz EM, Ahmed RP, Petrashevskaya N, Schwartz A, Boivin GP, Arteaga GM, Liggett SB, Solaro RJ, Wieczorek DF. An Internal Domain of Beta Tropomyosin Increases Myofilament Calcium Sensitivity Biophysical Journal. 96: 504a. DOI: 10.1016/J.Bpj.2008.12.2597 |
0.74 |
|
| 2008 |
Wieczorek DF, Jagatheesan G, Rajan S. The role of tropomyosin in heart disease. Advances in Experimental Medicine and Biology. 644: 132-42. PMID 19209819 DOI: 10.1007/978-0-387-85766-4_11 |
0.347 |
|
| 2008 |
Warren CM, Arteaga GM, Rajan S, Ahmed RP, Wieczorek DF, Solaro RJ. Use of 2-D DIGE analysis reveals altered phosphorylation in a tropomyosin mutant (Glu54Lys) linked to dilated cardiomyopathy. Proteomics. 8: 100-5. PMID 18095372 DOI: 10.1002/Pmic.200700772 |
0.398 |
|
| 2008 |
Schevzov G, Fath T, Vrhovski B, Vlahovich N, Rajan S, Hook J, Joya JE, Lemckert F, Puttur F, Lin JJ, Hardeman EC, Wieczorek DF, O'Neill GM, Gunning PW. Divergent regulation of the sarcomere and the cytoskeleton. The Journal of Biological Chemistry. 283: 275-83. PMID 17951248 DOI: 10.1074/Jbc.M704392200 |
0.397 |
|
| 2007 |
Rajan S, Ahmed RP, Jagatheesan G, Petrashevskaya N, Boivin GP, Urboniene D, Arteaga GM, Wolska BM, Solaro RJ, Liggett SB, Wieczorek DF. Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity. Circulation Research. 101: 205-14. PMID 17556658 DOI: 10.1161/Circresaha.107.148379 |
0.572 |
|
| 2007 |
Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Arteaga GM, Solaro RJ, Liggett SB, Wieczorek DF. Rescue of tropomyosin-induced familial hypertrophic cardiomyopathy mice by transgenesis. American Journal of Physiology. Heart and Circulatory Physiology. 293: H949-58. PMID 17416600 DOI: 10.1152/Ajpheart.01341.2006 |
0.495 |
|
| 2006 |
Rajan S, Williams SS, Jagatheesan G, Ahmed RP, Fuller-Bicer G, Schwartz A, Aronow BJ, Wieczorek DF. Microarray analysis of gene expression during early stages of mild and severe cardiac hypertrophy. Physiological Genomics. 27: 309-17. PMID 16882888 DOI: 10.1152/Physiolgenomics.00072.2006 |
0.486 |
|
| 2006 |
Babu GJ, Bhupathy P, Petrashevskaya NN, Wang H, Raman S, Wheeler D, Jagatheesan G, Wieczorek D, Schwartz A, Janssen PM, Ziolo MT, Periasamy M. Targeted overexpression of sarcolipin in the mouse heart decreases sarcoplasmic reticulum calcium transport and cardiac contractility. The Journal of Biological Chemistry. 281: 3972-9. PMID 16365042 DOI: 10.1074/Jbc.M508998200 |
0.515 |
|
| 2005 |
Zajdel RW, Denz CR, McLean MD, Dube S, Muthuchamy M, Poiesz BJ, Wieczorek DF, Dube DK. Diminished myofibril organization in mutant axolotl hearts transfected with site-directed mutants of sarcomeric tropomyosins. Cardiovascular Toxicology. 5: 75-90. PMID 15738587 DOI: 10.1385/Ct:5:1:075 |
0.421 |
|
| 2004 |
Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Arteaga G, de Tombe PP, Solaro RJ, Wieczorek DF. Physiological significance of troponin T binding domains in striated muscle tropomyosin. American Journal of Physiology. Heart and Circulatory Physiology. 287: H1484-94. PMID 15191887 DOI: 10.1152/Ajpheart.01112.2003 |
0.63 |
|
| 2003 |
Prabhakar R, Petrashevskaya N, Schwartz A, Aronow B, Boivin GP, Molkentin JD, Wieczorek DF. A mouse model of familial hypertrophic cardiomyopathy caused by a alpha-tropomyosin mutation. Molecular and Cellular Biochemistry. 251: 33-42. PMID 14575301 DOI: 10.1023/A:1025409227350 |
0.391 |
|
| 2003 |
Burkart EM, Arteaga GM, Sumandea MP, Prabhakar R, Wieczorek DF, Solaro RJ. Altered signaling surrounding the C-lobe of cardiac troponin C in myofilaments containing an alpha-tropomyosin mutation linked to familial hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 35: 1285-93. PMID 14519438 DOI: 10.1016/S0022-2828(03)00240-2 |
0.486 |
|
| 2003 |
Jagatheesan G, Rajan S, Petrashevskaya N, Schwartz A, Boivin G, Vahebi S, DeTombe P, Solaro RJ, Labitzke E, Hilliard G, Wieczorek DF. Functional importance of the carboxyl-terminal region of striated muscle tropomyosin. The Journal of Biological Chemistry. 278: 23204-11. PMID 12690096 DOI: 10.1074/Jbc.M303073200 |
0.577 |
|
| 2003 |
Prabhakar R, Petrashevskaya N, Schwartz A, Aronow B, Boivin GP, Molkentin JD, Wieczorek DF. A mouse model of familial hypertrophic cardiomyopathy caused by a α-tropomyosin mutation Molecular and Cellular Biochemistry. 251: 33-42. DOI: 10.1007/978-1-4419-9238-3_5 |
0.471 |
|
| 2002 |
Pieples K, Arteaga G, Solaro RJ, Grupp I, Lorenz JN, Boivin GP, Jagatheesan G, Labitzke E, DeTombe PP, Konhilas JP, Irving TC, Wieczorek DF. Tropomyosin 3 expression leads to hypercontractility and attenuates myofilament length-dependent Ca(2+) activation. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1344-53. PMID 12234784 DOI: 10.1152/Ajpheart.00351.2002 |
0.689 |
|
| 2001 |
MacGowan GA, Du C, Wieczorek DF, Koretsky AP. Compensatory changes in Ca(2+) and myocardial O(2) consumption in beta-tropomyosin transgenic hearts. American Journal of Physiology. Heart and Circulatory Physiology. 281: H2539-48. PMID 11709421 DOI: 10.1152/Ajpheart.2001.281.6.H2539 |
0.466 |
|
| 2001 |
Prabhakar R, Boivin GP, Grupp IL, Hoit B, Arteaga G, Solaro RJ, Wieczorek DF. A familial hypertrophic cardiomyopathy alpha-tropomyosin mutation causes severe cardiac hypertrophy and death in mice. Journal of Molecular and Cellular Cardiology. 33: 1815-28. PMID 11603924 DOI: 10.1006/Jmcc.2001.1445 |
0.558 |
|
| 2001 |
Patel JR, Fitzsimons DP, Buck SH, Muthuchamy M, Wieczorek DF, Moss RL. PKA accelerates rate of force development in murine skinned myocardium expressing α- or β-tropomyosin American Journal of Physiology - Heart and Circulatory Physiology. 280. PMID 11356630 |
0.321 |
|
| 2001 |
Prabhakar R, Boivin GP, grupp I, Artega G, Aronow B, Solaro R, Wieczorek DF. A mouse model for α-tropomyosin mutation that causes familial hypertrophic cardiomyopathy Journal of Molecular and Cellular Cardiology. 33: A96. DOI: 10.1016/S0022-2828(01)90381-5 |
0.309 |
|
| 2001 |
Prabhaker R, Boivin GP, Grupp IL, Hoit BD, Arteaga G, Solaro RJ, Wieczorek DF. Erratum: A familial hypertrophic cardiomyopathy α-tropomyosin mutation causes severe cardiac hypertrophy and death in mice (Journal of Molecular and Cellular Cardiology (2001) 33 (1815-1828)) Journal of Molecular and Cellular Cardiology. 33. DOI: 10.1006/Jmcc.2001.1487 |
0.41 |
|
| 2000 |
Evans CC, Pena JR, Phillips RM, Muthuchamy M, Wieczorek DF, Solaro RJ, Wolska BM. Altered hemodynamics in transgenic mice harboring mutant tropomyosin linked to hypertrophic cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 279: H2414-23. PMID 11045979 DOI: 10.1152/Ajpheart.2000.279.5.H2414 |
0.578 |
|
| 2000 |
Pieples K, Wieczorek DF. Tropomyosin 3 increases striated muscle isoform diversity. Biochemistry. 39: 8291-7. PMID 10889038 DOI: 10.1021/Bi000047X |
0.663 |
|
| 2000 |
Zajdel RW, McLean MD, Isitmangil G, Lemanski LF, Wieczorek DF, Dube DK. Alteration of cardiac myofibrillogenesis by liposome-mediated delivery of exogenous proteins and nucleic acids into whole embryonic hearts. Anatomy and Embryology. 201: 217-28. PMID 10794163 DOI: 10.1007/S004290050312 |
0.475 |
|
| 1999 |
Prabhakar R, Boivin GP, Hoit B, Wieczorek DF. Rescue of high expression beta-tropomyosin transgenic mice by 5-propyl-2-thiouracil. Regulating the alpha-myosin heavy chain promoter. The Journal of Biological Chemistry. 274: 29558-63. PMID 10506222 DOI: 10.1074/Jbc.274.41.29558 |
0.559 |
|
| 1999 |
Muthuchamy M, Pieples K, Rethinasamy P, Hoit B, Grupp IL, Boivin GP, Wolska B, Evans C, Solaro RJ, Wieczorek DF. Mouse model of a familial hypertrophic cardiomyopathy mutation in α- tropomyosin manifests cardiac dysfunction Circulation Research. 85: 47-56. PMID 10400910 DOI: 10.1161/01.Res.85.1.47 |
0.523 |
|
| 1999 |
Wolska BM, Keller RS, Evans CC, Palmiter KA, Phillips RM, Muthuchamy M, Oehlenschlager J, Wieczorek DF, de Tombe PP, Solaro RJ. Correlation between myofilament response to Ca2+ and altered dynamics of contraction and relaxation in transgenic cardiac cells that express beta-tropomyosin. Circulation Research. 84: 745-51. PMID 10205142 DOI: 10.1161/01.Res.84.7.745 |
0.549 |
|
| 1999 |
Hoit BD, Prabhakar R, Tramuta DA, Boivin GP, Wieczorek D. Influence of the α-Tropomyosin 180 mutation on in vivo left ventricular systolic and diastolic function Journal of Cardiac Failure. 5: 3. DOI: 10.1016/S1071-9164(99)91351-9 |
0.418 |
|
| 1998 |
Zajdel RW, Mclean MD, Lemanski SL, Muthuchamy M, Wieczorek DF, Lemanski LF, Dube DK. Ectopic expression of tropomyosin promotes myofibrillogenesis in mutant axolotl hearts Developmental Dynamics. 213: 412-420. PMID 9853962 DOI: 10.1002/(Sici)1097-0177(199812)213:4<412::Aid-Aja6>3.0.Co;2-C |
0.494 |
|
| 1998 |
Muthuchamy M, Boivin GP, Grupp IL, Wieczorek DF. β-tropomyosin overexpression induces severe cardiac abnormalities Journal of Molecular and Cellular Cardiology. 30: 1545-1557. PMID 9737941 DOI: 10.1006/Jmcc.1998.0720 |
0.53 |
|
| 1998 |
Sussman MA, Lim HW, Gude N, Taigen T, Olson EN, Robbins J, Colbert MC, Gualberto A, Wieczorek DF, Molkentin JD. Prevention of cardiac hypertrophy in mice by calcineurin inhibition. Science (New York, N.Y.). 281: 1690-3. PMID 9733519 DOI: 10.1126/Science.281.5383.1690 |
0.46 |
|
| 1998 |
Rethinasamy P, Muthuchamy M, Hewett T, Boivin G, Wolska BM, Evans C, Solaro RJ, Wieczorek DF. Molecular and physiological effects of α-tropomyosin ablation in the mouse Circulation Research. 82: 116-123. PMID 9440710 DOI: 10.1161/01.Res.82.1.116 |
0.482 |
|
| 1997 |
Muthuchamy M, Rethinasamy P, Wieczorek DF. Tropomyosin structure and function: New insights Trends in Cardiovascular Medicine. 7: 124-128. DOI: 10.1016/S1050-1738(97)00004-2 |
0.492 |
|
| 1996 |
Palmiter KA, Kitada Y, Muthuchamy M, Wieczorek DF, Solaro RJ. Exchange of β- for α-tropomyosin in hearts of transgenic mice induces changes in thin filament response to Ca2+, strong cross-bridge binding, and protein phosphorylation Journal of Biological Chemistry. 271: 11611-11614. PMID 8662805 DOI: 10.1074/Jbc.271.20.11611 |
0.516 |
|
| 1995 |
Muthuchamy M, Grupp IL, Grupp G, O' Toole BA, Kier AB, Boivin GP, Neumann J, Wieczorek DF. Molecular and physiological effects of overexpressing striated muscle β-tropomyosin in the adult murine heart Journal of Biological Chemistry. 270: 30593-30603. PMID 8530495 DOI: 10.1074/Jbc.270.51.30593 |
0.5 |
|
| 1993 |
Muthuchamy M, Pajak L, Howles P, Doetschman T, Wieczorek DF. Developmental analysis of tropomyosin gene expression in embryonic stem cells and mouse embryos Molecular and Cellular Biology. 13: 3311-3323. PMID 7684495 DOI: 10.1128/Mcb.13.6.3311 |
0.476 |
|
| 1991 |
Hasselgren P, Tricoli JV, Wieczorek D, Steigerwald KA, Angerås U, Hall-Angerås M, Fischer JE. Reduced levels of mRNA for myofibrillar proteins in skeletal muscle from septic rats. Life Sciences. 49: 753-760. PMID 1875785 DOI: 10.1016/0024-3205(91)90108-N |
0.403 |
|
| 1991 |
Pajak L, Mariappan M, Wieczorek DF. Reprogramming of myosin light chain 1/3 expression in muscle heterokaryons. Developmental Biology. 145: 28-39. PMID 1708345 DOI: 10.1016/0012-1606(91)90210-T |
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| 1988 |
Wieczorek DF, Smith CW, Nadal-Ginard B. The rat alpha-tropomyosin gene generates a minimum of six different mRNAs coding for striated, smooth, and nonmuscle isoforms by alternative splicing. Molecular and Cellular Biology. 8: 679-94. PMID 3352602 DOI: 10.1128/MCB.8.2.679 |
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| 1985 |
Wieczorek DF, Periasamy M, Butler-Browne GS, Whalen RG, Nadal-Ginard B. Co-expression of multiple myosin heavy chain genes, in addition to a tissue-specific one, in extraocular musculature. The Journal of Cell Biology. 101: 618-29. PMID 3894379 DOI: 10.1083/Jcb.101.2.618 |
0.432 |
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