Michael S. Rafii - Related publications

2008-2016 Neuroscience University of California, San Diego, La Jolla, CA 
 2016- Neurology University of Southern California Keck School of Medicine 
Neurodegenerative Diseases
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Ghosh S, Durgvanshi S, Agarwal S, Raghunath M, Sinha JK. Current status of drug targets and emerging therapeutic strategies in the management of Alzheimer's disease. Current Neuropharmacology. PMID 32348223 DOI: 10.2174/1570159X18666200429011823   
2020 Pérez-González M, Mendioroz M, Badesso S, Sucunza D, Roldan M, Espelosín M, Ursua S, Luján R, Cuadrado-Tejedor M, Garcia-Osta A. PLA2G4E, a candidate gene for resilience in Alzheimer´s disease and a new target for dementia treatment. Progress in Neurobiology. 101818. PMID 32380223 DOI: 10.1016/j.pneurobio.2020.101818   
2020 Kabir MT, Uddin MS, Mamun AA, Jeandet P, Aleya L, Mansouri RA, Ashraf GM, Mathew B, Bin-Jumah MN, Abdel-Daim MM. Combination Drug Therapy for the Management of Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32380758 DOI: 10.3390/ijms21093272   
2020 Zetterberg H, Bendlin BB. Biomarkers for Alzheimer's disease-preparing for a new era of disease-modifying therapies. Molecular Psychiatry. PMID 32251378 DOI: 10.1038/s41380-020-0721-9   
2020 McKeever A, Paris AF, Cullen J, Hayes L, Ritchie CW, Ritchie K, Waldman AD, Wells K, Busza A, Carriere I, O'Brien JT, Su L. Hippocampal Subfield Volumes in Middle-Aged Adults at Risk of Dementia. Journal of Alzheimer's Disease : Jad. PMID 32417786 DOI: 10.3233/JAD-200238   
2020 Mullane K, Williams M. Alzheimer's disease beyond amyloid: can the repetitive failures of amyloid-targeted therapeutics inform future approaches to dementia drug discovery? Biochemical Pharmacology. 113945. PMID 32247851 DOI: 10.1016/j.bcp.2020.113945   
2020 Ren J, Zhang B, Wei D, Zhang Z. Identification of Methylated Gene Biomarkers in Patients with Alzheimer's Disease Based on Machine Learning. Biomed Research International. 2020: 8348147. PMID 32309439 DOI: 10.1155/2020/8348147   
2020 Risacher SL, WuDunn D, Tallman EF, West JD, Gao S, Farlow MR, Brosch JR, Apostolova LG, Saykin AJ. Visual contrast sensitivity is associated with the presence of cerebral amyloid and tau deposition. Brain Communications. 2: fcaa019. PMID 32309804 DOI: 10.1093/braincomms/fcaa019   
2020 Rostamzadeh A, Jessen F. [Early detection of Alzheimer's disease and dementia prediction in patients with mild cognitive impairment : Summary of current recommendations]. Der Nervenarzt. PMID 32300816 DOI: 10.1007/s00115-020-00907-y   
2020 Rossini PM, Di Iorio R, Vecchio F, Anfossi M, Babiloni C, Bozzali M, Bruni AC, Cappa SF, Escudero J, Fraga FJ, Giannakopoulos P, Guntekin B, Logroscino G, Marra C, Miraglia F, et al. Early diagnosis of Alzheimer's disease: the role of biomarkers including advanced EEG signal analysis. Report from the IFCN-sponsored panel of experts. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 131: 1287-1310. PMID 32302946 DOI: 10.1016/j.clinph.2020.03.003   
2020 Pichet Binette A, Vachon-Presseau É, Morris J, Bateman R, Benzinger T, Collins DL, Poirier J, Breitner JCS, Villeneuve S, , . Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease. Biological Psychiatry. PMID 32228870 DOI: 10.1016/j.biopsych.2020.01.023   
2020 Malpas CB, Sharmin S, Kalincik T. The histopathological staging of tau, but not amyloid, corresponds to antemortem cognitive status, dementia stage, functional abilities, and neuropsychiatric symptoms. The International Journal of Neuroscience. 1-13. PMID 32303140 DOI: 10.1080/00207454.2020.1758087   
2020 Lee C, Willerth SM, Nygaard HB. The Use of Patient-Derived Induced Pluripotent Stem Cells for Alzheimer's Disease Modeling. Progress in Neurobiology. 101804. PMID 32464173 DOI: 10.1016/j.pneurobio.2020.101804   
2020 Vyas Y, Montgomery JM, Cheyne JE. Hippocampal Deficits in Amyloid-β-Related Rodent Models of Alzheimer's Disease. Frontiers in Neuroscience. 14: 266. PMID 32317913 DOI: 10.3389/fnins.2020.00266   
2020 Qin T, Prins S, Groeneveld GJ, Van Westen G, de Vries HE, Wong YC, Bischoff LJM, de Lange ECM. Utility of Animal Models to Understand Human Alzheimer's Disease, Using the Mastermind Research Approach to Avoid Unnecessary Further Sacrifices of Animals. International Journal of Molecular Sciences. 21. PMID 32365768 DOI: 10.3390/ijms21093158   
2020 Chen SY, Gao Y, Sun JY, Meng XL, Yang D, Fan LH, Xiang L, Wang P. Traditional Chinese Medicine: Role in Reducing β-Amyloid, Apoptosis, Autophagy, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction of Alzheimer's Disease. Frontiers in Pharmacology. 11: 497. PMID 32390843 DOI: 10.3389/fphar.2020.00497   
2020 Rai L, Boyle R, Brosnan L, Rice H, Farina F, Tarnanas I, Whelan R. Digital Biomarkers Based Individualized Prognosis for People at Risk of Dementia: the AltoidaML Multi-site External Validation Study. Advances in Experimental Medicine and Biology. 1194: 157-171. PMID 32468532 DOI: 10.1007/978-3-030-32622-7_14   
2020 Upadhyaya Y, Xie L, Salama P, Cao S, Nho K, Saykin AJ, Yan J, Alzheimer's Disease Neuroimaging Initiative FT. Differential co-expression analysis reveals early stage transcriptomic decoupling in alzheimer's disease. Bmc Medical Genomics. 13: 53. PMID 32241275 DOI: 10.1186/s12920-020-0689-y   
2020 Sultan S, Taimuri U, Basnan SA, Ai-Orabi WK, Awadallah A, Almowald F, Hazazi A. Low Vitamin D and Its Association with Cognitive Impairment and Dementia. Journal of Aging Research. 2020: 6097820. PMID 32399297 DOI: 10.1155/2020/6097820   
2020 Gan CL, Zhang T, Lee TH. The Genetics of Alzheimer's Disease in the Chinese Population. International Journal of Molecular Sciences. 21. PMID 32235595 DOI: 10.3390/ijms21072381   
2020 Novak G, Streffer JR, Timmers M, Henley D, Brashear HR, Bogert J, Russu A, Janssens L, Tesseur I, Tritsmans L, Van Nueten L, Engelborghs S. Long-term safety and tolerability of atabecestat (JNJ-54861911), an oral BACE1 inhibitor, in early Alzheimer's disease spectrum patients: a randomized, double-blind, placebo-controlled study and a two-period extension study. Alzheimer's Research & Therapy. 12: 58. PMID 32410694 DOI: 10.1186/s13195-020-00614-5   
2020 Eke CS, Jammeh E, Li X, Carroll C, Pearson S, Ifeachor E. Early Detection of Alzheimer's Disease with Blood Plasma Proteins using Support Vector Machines. Ieee Journal of Biomedical and Health Informatics. PMID 32340968 DOI: 10.1109/JBHI.2020.2984355   
2020 Uddin MS, Kabir MT, Mamun AA, Barreto GE, Rashid M, Perveen A, Ashraf GM. Pharmacological approaches to mitigate neuroinflammation in Alzheimer's disease. International Immunopharmacology. 84: 106479. PMID 32353686 DOI: 10.1016/j.intimp.2020.106479   
2020 Gee MS, Son SH, Jeon SH, Do J, Kim N, Ju YJ, Lee SJ, Chung EK, Inn KS, Kim NJ, Lee JK. A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse. Alzheimer's Research & Therapy. 12: 45. PMID 32317025 DOI: 10.1186/s13195-020-00617-2   
2020 Khandker RK, Ritchie CW, Black CM, Wood R, Jones E, Hu X, Ambegaonkar BM. Multi-National, Cross-Sectional Survey of Healthcare Resource Utilization in Patients with All Stages of Cognitive Impairment, Analyzed by Disease Severity, Country, and Geographical Region. Journal of Alzheimer's Disease : Jad. PMID 32390613 DOI: 10.3233/JAD-190760   
2020 Santangelo R, Masserini F, Agosta F, Sala A, Caminiti SP, Cecchetti G, Caso F, Martinelli V, Pinto P, Passerini G, Perani D, Magnani G, Filippi M. CSF p-tau/Aβ ratio and brain FDG-PET may reliably detect MCI "imminent" converters to AD. European Journal of Nuclear Medicine and Molecular Imaging. PMID 32415550 DOI: 10.1007/s00259-020-04853-4   
2020 Shi Y, Zeng W, Deng J, Nie W, Zhang Y. The Identification of Alzheimer's Disease Using Functional Connectivity Between Activity Voxels in Resting-State fMRI Data. Ieee Journal of Translational Engineering in Health and Medicine. 8: 1400211. PMID 32355582 DOI: 10.1109/JTEHM.2020.2985022   
2020 Cole MA, Seabrook GR. On the horizon-the value and promise of the global pipeline of Alzheimer's disease therapeutics. Alzheimer's & Dementia (New York, N. Y.). 6: e12009. PMID 32405530 DOI: 10.1002/trc2.12009   
2020 Souza VC, Morais GS, Henriques AD, Machado-Silva W, Perez DIV, Brito CJ, Camargos EF, Moraes CF, Nóbrega OT. Whole-Blood Levels of MicroRNA-9 Are Decreased in Patients With Late-Onset Alzheimer Disease. American Journal of Alzheimer's Disease and Other Dementias. 35: 1533317520911573. PMID 32301334 DOI: 10.1177/1533317520911573   
2020 Husna Ibrahim N, Yahaya MF, Mohamed W, Teoh SL, Hui CK, Kumar J. Pharmacotherapy of Alzheimer's Disease: Seeking Clarity in a Time of Uncertainty. Frontiers in Pharmacology. 11: 261. PMID 32265696 DOI: 10.3389/fphar.2020.00261   
2020 Andrade V, Cortés N, Pastor G, Gonzalez A, Ramos-Escobar N, Pastene E, Rojo LE, Maccioni RB. N-Acetyl Cysteine and Catechin-Derived Polyphenols: A Path Toward Multi-Target Compounds Against Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 32390631 DOI: 10.3233/JAD-200067   
2020 Angelopoulou E, Paudel YN, Shaikh MF, Piperi C. Flotillin: A Promising Biomarker for Alzheimer's Disease. Journal of Personalized Medicine. 10. PMID 32225073 DOI: 10.3390/jpm10020020   
2020 Xue M, Sun FR, Ou YN, Shen XN, Li HQ, Huang YY, Dong Q, Tan L, Yu JT, . Association of cerebrospinal fluid neurogranin levels with cognition and neurodegeneration in Alzheimer's disease. Aging. 12. PMID 32421689 DOI: 10.18632/aging.103211   
2020 Leblhuber F, Steiner K, Geisler S, Fuchs D, Gostner JM. On the possible relevance of bottom-up pathways in the pathogenesis of Alzheimer's dementia. Current Topics in Medicinal Chemistry. PMID 32407280 DOI: 10.2174/1568026620666200514090359   
2020 Ahmadzadeh M, Christie GJ, Cosco TD, Moreno S. Neuroimaging and analytical methods for studying the pathways from mild cognitive impairment to Alzheimer's disease: protocol for a rapid systematic review. Systematic Reviews. 9: 71. PMID 32241302 DOI: 10.1186/s13643-020-01332-7   
2020 Liu S, Dang M, Lei Y, Ahmad SS, Khalid M, Kamal MA, Chen L. Ajmalicine and its Analogues against AChE and BuChE for the Management of Alzheimer's Disease: An In-silico study. Current Pharmaceutical Design. PMID 32264807 DOI: 10.2174/1381612826666200407161842   
2020 Riching AS, Major JL, Londono P, Bagchi RA. The Brain-Heart Axis: Alzheimer's, Diabetes, and Hypertension. Acs Pharmacology & Translational Science. 3: 21-28. PMID 32259085 DOI: 10.1021/acsptsci.9b00091   
2020 Zhang Y, Ren B, Zhang D, Liu Y, Zhang M, Zhao C, Zheng J. Design principles and fundamental understanding of biosensors for amyloid-β detection. Journal of Materials Chemistry. B. PMID 32355946 DOI: 10.1039/d0tb00344a   
2020 Bernath MM, Bhattacharyya S, Nho K, Barupal DK, Fiehn O, Baillie R, Risacher SL, Arnold M, Jacobson T, Trojanowski JQ, Shaw LM, Weiner MW, Doraiswamy PM, Kaddurah-Daouk R, Saykin AJ, , et al. Serum triglycerides in Alzheimer disease: Relation to neuroimaging and CSF biomarkers. Neurology. PMID 32358220 DOI: 10.1212/WNL.0000000000009436   
2020 Malpetti M, Kievit RA, Passamonti L, Jones PS, Tsvetanov KA, Rittman T, Mak E, Nicastro N, Bevan-Jones WR, Su L, Hong YT, Fryer TD, Aigbirhio FI, O'Brien JT, Rowe JB. Microglial activation and tau burden predict cognitive decline in Alzheimer's disease. Brain : a Journal of Neurology. PMID 32380523 DOI: 10.1093/brain/awaa088   
2020 Yeong KY, Law C. Repurposing Antihypertensive Drugs for the Management of Alzheimer's Disease. Current Medicinal Chemistry. PMID 32164502 DOI: 10.2174/0929867327666200312114223   
2020 Nguyen TT, Ta QTH, Nguyen TKO, Nguyen TTD, Vo VG. Role of Body-Fluid Biomarkers in Alzheimer's Disease Diagnosis. Diagnostics (Basel, Switzerland). 10. PMID 32443860 DOI: 10.3390/diagnostics10050326   
2020 Amponsah AE, Feng B, Guo R, Zhang W, He J, Kong D, Dong T, Ma J, Cui H. Fragmentation of brain apolipoprotein E (ApoE) and its relevance in Alzheimer's disease. Reviews in the Neurosciences. PMID 32364519 DOI: 10.1515/revneuro-2019-0115   
2020 Euesden J, Gowrisankar S, Qu AX, Jean PS, Hughes AR, Pulford DJ. Cognitive Decline in Alzheimer's Disease: Limited Clinical Utility for GWAS or Polygenic Risk Scores in a Clinical Trial Setting. Genes. 11. PMID 32370229 DOI: 10.3390/genes11050501   
2020 Insel PS, Donohue MC, Sperling R, Hansson O, Mattsson-Carlgren N. The A4 study: β-amyloid and cognition in 4432 cognitively unimpaired adults. Annals of Clinical and Translational Neurology. PMID 32315118 DOI: 10.1002/acn3.51048   
2020 Singh H, Chawla V, Bala R, Dureja H. Current and Future of Alzheimer's therapy with the best approach. Cns & Neurological Disorders Drug Targets. PMID 32351189 DOI: 10.2174/1871527319666200430000538   
2020 Lee JJ, Choi GJ, Kang H, Baek CW, Jung YH, Shin HY, Park YH, Woo YC. Relationship between Surgery under General Anesthesia and the Development of Dementia: A Systematic Review and Meta-Analysis. Biomed Research International. 2020: 3234013. PMID 32337238 DOI: 10.1155/2020/3234013   
2020 Jacobs HIL, Augustinack JC, Schultz AP, Hanseeuw BJ, Locascio J, Amariglio RE, Papp KV, Rentz DM, Sperling RA, Johnson KA. The presubiculum links incipient amyloid and tau pathology to memory function in older persons. Neurology. PMID 32273431 DOI: 10.1212/WNL.0000000000009362   
2020 Xu XD, Teng Y, Zou JY, Ye Y, Song H, Wang ZY. Effects of lycopene on vascular remodeling through the LXR-PI3K-AKT signaling pathway in APP/PS1 mice. Biochemical and Biophysical Research Communications. PMID 32253029 DOI: 10.1016/j.bbrc.2020.02.063   
2020 Kou X, Chen D, Chen N. The Regulation of microRNAs in Alzheimer's Disease. Frontiers in Neurology. 11: 288. PMID 32362867 DOI: 10.3389/fneur.2020.00288