Adam C. Gower, Ph.D. - Publications

Affiliations: 
2012 Boston University, Boston, MA, United States 
Area:
Bioinformatics Biology, Genetics

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Yanagawa J, Tran LM, Salehi-Rad R, Lim RJ, Dumitras C, Fung E, Wallace WD, Prosper AE, Fishbein G, Shea C, Hong R, Kahangi B, Deng JJ, Gower AC, Liu B, et al. Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma. Cancer Research. PMID 37477508 DOI: 10.1158/0008-5472.CAN-23-0128  0.699
2022 Xu K, Shi X, Husted C, Hong R, Wang Y, Ning B, Sullivan TB, Rieger-Christ KM, Duan F, Marques H, Gower AC, Xiao X, Liu H, Liu G, Duclos G, et al. Smoking modulates different secretory subpopulations expressing SARS-CoV-2 entry genes in the nasal and bronchial airways. Scientific Reports. 12: 18168. PMID 36307504 DOI: 10.1038/s41598-022-17832-6  0.693
2022 Xu K, Diaz AA, Duan F, Lee M, Xiao X, Liu H, Liu G, Cho MH, Gower AC, Alekseyev YO, Spira A, Aberle DR, Washko GR, Billatos E, Lenburg ME. Bronchial Gene Expression Alterations Associated with Radiographic Bronchiectasis. The European Respiratory Journal. PMID 36229050 DOI: 10.1183/13993003.00120-2022  0.547
2021 Xu K, Shi X, Husted C, Hong R, Wang Y, Ning B, Sullivan T, Rieger-Christ K, Duan F, Marques H, Gower A, Xiao X, Liu H, Liu G, Duclos G, et al. Smoking Modulates Different Secretory Subpopulations Expressing SARS-CoV-2 Entry Genes in the Nasal and Bronchial Airways. Research Square. PMID 34729557 DOI: 10.21203/rs.3.rs-887718/v1  0.685
2021 Maoz A, Merenstein C, Koga Y, Potter A, Gower AC, Liu G, Zhang S, Liu H, Stevenson C, Spira A, Reid ME, Campbell JD, Mazzilli SA, Lenburg ME, Beane J. Elevated T cell repertoire diversity is associated with progression of lung squamous cell premalignant lesions. Journal For Immunotherapy of Cancer. 9. PMID 34580161 DOI: 10.1136/jitc-2021-002647  0.64
2020 Sofer T, Li R, Joehanes R, Lin H, Gower AC, Wang H, Kurniansyah N, Cade BE, Lee J, Williams S, Mehra R, Patel SR, Quan SF, Liu Y, Rotter JI, et al. Low oxygen saturation during sleep reduces CD1D and RAB20 expressions that are reversed by CPAP therapy. Ebiomedicine. 56: 102803. PMID 32512511 DOI: 10.1016/J.Ebiom.2020.102803  0.494
2019 Norman TA, Gower AC, Chen F, Fine A. Transcriptional landscape of pulmonary lymphatic endothelial cells during fetal gestation. Plos One. 14: e0216795. PMID 31083674 DOI: 10.1371/Journal.Pone.0216795  0.412
2019 Sofer T, Li R, Joehanes R, Lin H, Gower A, Punjabi N, Mehra R, Patel S, Quan S, Liu Y, Gharib S, Levy D, Spira A, Redline S, Gottlieb D. 0021 Lower Oxygen Saturation During Sleep Is Associated With Reduced Expressions Of Cd1d And Rab20 That Is Potentially Reversed By CPAP Therapy Sleep. 42: A8-A9. DOI: 10.1093/Sleep/Zsz067.020  0.499
2018 Abdolmaleky HM, Gower AC, Wong CK, Cox JW, Zhang X, Thiagalingam A, Shafa R, Sivaraman V, Zhou JR, Thiagalingam S. Aberrant transcriptomes and DNA methylomes define pathways that drive pathogenesis and loss of brain laterality/asymmetry in schizophrenia and bipolar disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 30468562 DOI: 10.1002/Ajmg.B.32691  0.414
2018 Kathuria H, Millien G, McNally L, Gower AC, Tagne JB, Cao Y, Ramirez MI. NKX2-1-AS1 negatively regulates CD274/PD-L1, cell-cell interaction genes, and limits human lung carcinoma cell migration. Scientific Reports. 8: 14418. PMID 30258080 DOI: 10.1038/S41598-018-32793-5  0.426
2018 Noguchi T, Hussein AI, Horowitz N, Carroll D, Gower AC, Demissie S, Gerstenfeld LC. Hypophosphatemia Regulates Molecular Mechanisms of Circadian Rhythm. Scientific Reports. 8: 13756. PMID 30213970 DOI: 10.1038/S41598-018-31830-7  0.348
2018 Pine PS, Lund SP, Parsons JR, Vang LK, Mahabal AA, Cinquini L, Kelly SC, Kincaid H, Crichton DJ, Spira A, Liu G, Gower AC, Pass HI, Goparaju C, Dubinett SM, et al. Summarizing performance for genome scale measurement of miRNA: reference samples and metrics. Bmc Genomics. 19: 180. PMID 29510677 DOI: 10.1186/S12864-018-4496-1  0.517
2017 Kozlowski E, Wasserman GA, Morgan M, O'Carroll D, Ramirez NP, Gummuluru S, Rah JY, Gower AC, Ieong M, Quinton LJ, Mizgerd JP, Jones MR. The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses. Plos One. 12: e0179797. PMID 28665939 DOI: 10.1371/Journal.Pone.0179797  0.365
2017 Muñoz-Largacha JA, Gower AC, Sridhar P, Deshpande A, O'Hara CJ, Yamada E, Godfrey TE, Fernando HC, Litle VR. miRNA profiling of primary lung and head and neck squamous cell carcinomas: Addressing a diagnostic dilemma. The Journal of Thoracic and Cardiovascular Surgery. PMID 28495058 DOI: 10.1016/J.Jtcvs.2017.02.071  0.359
2017 Szymaniak AD, Mi R, McCarthy SE, Gower AC, Reynolds TL, Mingueneau M, Kukuruzinska M, Varelas X. The Hippo pathway effector YAP is an essential regulator of ductal progenitor patterning in the mouse submandibular gland. Elife. 6. PMID 28492365 DOI: 10.7554/Elife.23499  0.319
2017 Gower AC, Spira A, Lenburg ME. 2356 Journal of Clinical and Translational Science. 1: 16-16. DOI: 10.1017/cts.2017.71  0.509
2016 Pickering RT, Lee MJ, Karastergiou K, Gower A, Fried SK. Depot Dependent Effects of Dexamethasone on Gene Expression in Human Omental and Abdominal Subcutaneous Adipose Tissues from Obese Women. Plos One. 11: e0167337. PMID 28005982 DOI: 10.1371/Journal.Pone.0167337  0.321
2016 Chitsazzadeh V, Coarfa C, Drummond JA, Nguyen T, Joseph A, Chilukuri S, Charpiot E, Adelmann CH, Ching G, Nguyen TN, Nicholas C, Thomas VD, Migden M, MacFarlane D, Thompson E, ... ... Gower A, et al. Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates. Nature Communications. 7: 12601. PMID 27574101 DOI: 10.1038/Ncomms12601  0.536
2016 Kamata H, Yamamoto K, Wasserman GA, Zabinski MC, Yuen CK, Lung WY, Gower AC, Belkina AC, Ramirez MI, Deng JC, Quinton LJ, Jones MR, Mizgerd JP. Epithelial Cell-derived Secreted and Transmembrane 1a (Sectm1a) Signals to Activated Neutrophils During Pneumococcal Pneumonia. American Journal of Respiratory Cell and Molecular Biology. PMID 27064756 DOI: 10.1165/Rcmb.2015-0261Oc  0.482
2016 Munoz J, Sridhar P, Gower A, Deshpande A, Alekseyev Y, O'Hara C, Fernando H, Litle V. miRNA Profiling of Lung Squamous Cell Carcinoma in the Head and Neck Cancer Patient: Metastasis or Primary Tumor? Chest. 149: A286. DOI: 10.1016/J.Chest.2016.02.298  0.371
2015 Lambert AW, Wong CK, Ozturk S, Papageorgis P, Raghunathan R, Alekseyev Y, Gower AC, Reinhard BM, Abdolmaleky HM, Thiagalingam S. Tumor Cell-Derived Periostin Regulates Cytokines That Maintain Breast Cancer Stem Cells. Molecular Cancer Research : McR. PMID 26507575 DOI: 10.1158/1541-7786.Mcr-15-0079  0.331
2015 Whitney DH, Elashoff MR, Porta-Smith K, Gower AC, Vachani A, Ferguson JS, Silvestri GA, Brody JS, Lenburg ME, Spira A. Derivation of a bronchial genomic classifier for lung cancer in a prospective study of patients undergoing diagnostic bronchoscopy. Bmc Medical Genomics. 8: 18. PMID 25944280 DOI: 10.1186/S12920-015-0091-3  0.654
2015 Wilson AA, Ying L, Liesa M, Segeritz CP, Mills JA, Shen SS, Jean J, Lonza GC, Liberti DC, Lang AH, Nazaire J, Gower AC, Müeller FJ, Mehta P, Ordóñez A, et al. Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells. Stem Cell Reports. 4: 873-85. PMID 25843048 DOI: 10.1016/J.Stemcr.2015.02.021  0.543
2015 Zhu Y, Tchkonia T, Pirtskhalava T, Gower AC, Ding H, Giorgadze N, Palmer AK, Ikeno Y, Hubbard GB, Lenburg M, O'Hara SP, LaRusso NF, Miller JD, Roos CM, Verzosa GC, et al. The Achilles' heel of senescent cells: from transcriptome to senolytic drugs. Aging Cell. 14: 644-58. PMID 25754370 DOI: 10.1111/Acel.12344  0.313
2014 Kramer CD, Weinberg EO, Gower AC, He X, Mekasha S, Slocum C, Beaulieu LM, Wetzler L, Alekseyev Y, Gibson FC, Freedman JE, Ingalls RR, Genco CA. Distinct gene signatures in aortic tissue from ApoE-/- mice exposed to pathogens or Western diet. Bmc Genomics. 15: 1176. PMID 25540039 DOI: 10.1186/1471-2164-15-1176  0.311
2014 Ooi AT, Gower AC, Zhang KX, Vick JL, Hong L, Nagao B, Wallace WD, Elashoff DA, Walser TC, Dubinett SM, Pellegrini M, Lenburg ME, Spira A, Gomperts BN. Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis. Cancer Prevention Research (Philadelphia, Pa.). 7: 487-95. PMID 24618292 DOI: 10.1158/1940-6207.Capr-13-0372  0.633
2014 Guha A, Vasconcelos M, Zhao R, Gower AC, Rajagopal J, Cardoso WV. Analysis of Notch signaling-dependent gene expression in developing airways reveals diversity of Clara cells. Plos One. 9: e88848. PMID 24586412 DOI: 10.1371/Journal.Pone.0088848  0.481
2014 Kadara H, Fujimoto J, Yoo SY, Maki Y, Gower AC, Kabbout M, Garcia MM, Chow CW, Chu Z, Mendoza G, Shen L, Kalhor N, Hong WK, Moran C, Wang J, et al. Transcriptomic architecture of the adjacent airway field cancerization in non-small cell lung cancer. Journal of the National Cancer Institute. 106: dju004. PMID 24563515 DOI: 10.1093/Jnci/Dju004  0.632
2014 Maki Y, Fujimoto J, Yoo S, Garcia M, Gower A, Shen L, Chow C, Behrens C, Kalhor N, Moran C, Wang J, Spira A, Coombes KR, Wistuba II, Kadara H. Abstract 1597: Transcriptomic architecture of the field of cancerization in the adjacent normal-appearing airway: Early mechanisms in lung carcinogenesis Cancer Research. 74: 1597-1597. DOI: 10.1158/1538-7445.Am2014-1597  0.659
2013 Perdomo C, Campbell JD, Gerrein J, Tellez CS, Garrison CB, Walser TC, Drizik E, Si H, Gower AC, Vick J, Anderlind C, Jackson GR, Mankus C, Schembri F, O'Hara C, et al. MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 18946-51. PMID 24158479 DOI: 10.1073/Pnas.1220319110  0.721
2013 Mills JA, Wang K, Paluru P, Ying L, Lu L, Galvão AM, Xu D, Yao Y, Sullivan SK, Sullivan LM, Mac H, Omari A, Jean JC, Shen S, Gower A, et al. Clonal genetic and hematopoietic heterogeneity among human-induced pluripotent stem cell lines. Blood. 122: 2047-51. PMID 23940280 DOI: 10.1182/Blood-2013-02-484444  0.314
2013 Govender P, Romero F, Shah D, Paez J, Ding SY, Liu L, Gower A, Baez E, Aly SS, Pilch P, Summer R. Cavin1; a regulator of lung function and macrophage phenotype. Plos One. 8: e62045. PMID 23634221 DOI: 10.1371/Journal.Pone.0062045  0.431
2013 Maki Y, Fujimoto J, Yoo S, Gower A, Shen L, Garcia MM, Kabbout M, Chow C, Hong WK, Kalhor N, Wang J, Moran C, Spira A, Coombes KR, Wistuba II, et al. Abstract 2367: Transcriptomic architecture of the airway field cancerization in early-stage non-small cell lung cancer . Cancer Research. 73: 2367-2367. DOI: 10.1158/1538-7445.Am2013-2367  0.673
2013 Ooi AT, Gower A, Zhang K, Vick J, Hong L, Fishbein M, Nagao B, Wallace WD, Elashoff D, Lenburg M, Dubinett S, Spira A, Gomperts B. Abstract 1063: Examining early events in carcinogenesis by profiling premalignant lesions in the airways of patients with lung squamous cell carcinomas. Cancer Research. 73: 1063-1063. DOI: 10.1158/1538-7445.Am2013-1063  0.662
2012 Tagne JB, Gupta S, Gower AC, Shen SS, Varma S, Lakshminarayanan M, Cao Y, Spira A, Volkert TL, Ramirez MI. Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors. Plos One. 7: e29907. PMID 22242187 DOI: 10.1371/Journal.Pone.0029907  0.649
2012 Perdomo C, Campbell J, Gerrein J, Tellez C, Gower A, Vick J, Garrison C, Anderlind C, Jackson GR, Schembri F, Gomperts BN, Hayden P, Belinsky SA, Lenburg ME, Spira A. Abstract 3173: Identification of miR-4423 as a primate-specific microRNA highly expressed in airway epithelium and associated with lung cancer Cancer Research. 72: 3173-3173. DOI: 10.1158/1538-7445.Am2012-3173  0.729
2012 Gilbert JL, Maresh E, Mah V, Gower A, Goodglick L, Gomperts B. Abstract 1042: Down-regulation of UTX contributes to lung cancer progression Cancer Research. 72: 1042-1042. DOI: 10.1158/1538-7445.Am2012-1042  0.541
2011 Gower AC, Spira A, Lenburg ME. Discovering biological connections between experimental conditions based on common patterns of differential gene expression. Bmc Bioinformatics. 12: 381. PMID 21951600 DOI: 10.1186/1471-2105-12-381  0.585
2011 Beane J, Vick J, Schembri F, Anderlind C, Gower A, Campbell J, Luo L, Zhang XH, Xiao J, Alekseyev YO, Wang S, Levy S, Massion PP, Lenburg M, Spira A. Characterizing the impact of smoking and lung cancer on the airway transcriptome using RNA-Seq. Cancer Prevention Research (Philadelphia, Pa.). 4: 803-17. PMID 21636547 DOI: 10.1158/1940-6207.Capr-11-0212  0.728
2011 Gower AC, Steiling K, Brothers JF, Lenburg ME, Spira A. Transcriptomic studies of the airway field of injury associated with smoking-related lung disease. Proceedings of the American Thoracic Society. 8: 173-9. PMID 21543797 DOI: 10.1513/pats.201011-066MS  0.757
2011 Gerrein J, Perdomo C, Campbell JD, Vick J, Gower A, Anderlind C, Schembri F, Lenburg M, Spira A. Abstract 3989: Discovery of a novel airway microRNA associated with lung cancer using next generation sequencing Cellular and Molecular Biology. 71: 3989-3989. DOI: 10.1158/1538-7445.Am2011-3989  0.692
2010 Ooi AT, Mah V, Nickerson DW, Gilbert JL, Ha VL, Hegab AE, Horvath S, Alavi M, Maresh EL, Chia D, Gower AC, Lenburg ME, Spira A, Solis LM, Wistuba II, et al. Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer. Cancer Research. 70: 6639-48. PMID 20710044 DOI: 10.1158/0008-5472.Can-10-0455  0.646
2010 Ooi AT, Mah VH, Nickerson DW, Gilbert JL, Ha VL, Hegab AE, Horvath S, Alavi M, Maresh E, Chia D, Gower AC, Lenburg ME, Spira A, Walser T, Wallace WD, et al. Abstract 4299: Poor prognosis in smokers with non-small cell lung cancer correlates with the presence of a reparative progenitor cell population Cancer Research. 70: 4299-4299. DOI: 10.1158/1538-7445.Am10-4299  0.631
2002 Reed KL, Fruin AB, Bishop-Bartolomei KK, Gower AC, Nicolaou M, Stucchi AF, Leeman SE, Becker JM. Neurokinin-1 receptor and substance P messenger RNA levels increase during intraabdominal adhesion formation. The Journal of Surgical Research. 108: 165-72. PMID 12443729 DOI: 10.1006/Jsre.2002.6533  0.306
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