Patrick J. Burke, Ph.D. - Publications

Affiliations: 
2003 University of Colorado, Boulder, Boulder, CO, United States 
Area:
Organic Chemistry

12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hamilton JZ, Pires TA, Mitchell JA, Cochran JH, Emmerton KK, Zaval M, Stone IJ, Anderson ME, Jin S, Waight AB, Lyon RP, Senter PD, Jeffrey SC, Burke PJ. Improving Antibody-Tubulysin Conjugates Through Linker Chemistry and Site-Specific Conjugation. Chemmedchem. PMID 33369163 DOI: 10.1002/cmdc.202000889  0.316
2018 Burke PJ, Hamilton JZ, Pires TA, Lai HWH, Leiske CI, Emmerton KK, Waight AB, Senter PD, Lyon RP, Jeffrey SC. Glucuronide-linked antibody-tubulysin conjugates display activity in MDR+ and heterogeneous tumor models. Molecular Cancer Therapeutics. PMID 29866744 DOI: 10.1158/1535-7163.MCT-18-0073  0.308
2013 Kung Sutherland MS, Walter RB, Jeffrey SC, Burke PJ, Yu C, Kostner H, Stone I, Ryan MC, Sussman D, Lyon RP, Zeng W, Harrington KH, Klussman K, Westendorf L, Meyer D, et al. SGN-CD33A: a novel CD33-targeting antibody-drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML. Blood. 122: 1455-63. PMID 23770776 DOI: 10.1182/blood-2013-03-491506  0.32
2009 Burke PJ, Senter PD, Meyer DW, Miyamoto JB, Anderson M, Toki BE, Manikumar G, Wani MC, Kroll DJ, Jeffrey SC. Design, synthesis, and biological evaluation of antibody-drug conjugates comprised of potent camptothecin analogues. Bioconjugate Chemistry. 20: 1242-50. PMID 19469529 DOI: 10.1021/bc9001097  0.303
2009 Burke PJ, Toki BE, Meyer DW, Miyamoto JB, Kissler KM, Anderson M, Senter PD, Jeffrey SC. Novel immunoconjugates comprised of streptonigrin and 17-amino-geldanamycin attached via a dipeptide-p-aminobenzyl-amine linker system. Bioorganic & Medicinal Chemistry Letters. 19: 2650-3. PMID 19386499 DOI: 10.1016/j.bmcl.2009.03.145  0.334
2004 Burke PJ, Kalet BT, Koch TH. Antiestrogen binding site and estrogen receptor mediate uptake and distribution of 4-hydroxytamoxifen-targeted doxorubicin-formaldehyde conjugate in breast cancer cells. Journal of Medicinal Chemistry. 47: 6509-18. PMID 15588086 DOI: 10.1021/Jm049496B  0.485
2004 Burke PJ, Koch TH. Design, synthesis, and biological evaluation of doxorubicin-formaldehyde conjugates targeted to breast cancer cells. Journal of Medicinal Chemistry. 47: 1193-206. PMID 14971899 DOI: 10.1021/Jm030352R  0.681
2004 Itharat A, Houghton PJ, Eno-Amooquaye E, Burke PJ, Sampson JH, Raman A. In vitro cytotoxic activity of Thai medicinal plants used traditionally to treat cancer Journal of Ethnopharmacology. 90: 33-38. PMID 14698505 DOI: 10.1016/j.jep.2003.09.014  0.323
2001 Burke PJ, Koch TH. Doxorubicin-formaldehyde conjugate, doxoform: induction of apoptosis relative to doxorubicin. Anticancer Research. 21: 2753-60. PMID 11724351  0.586
2001 Kato S, Burke PJ, Koch TH, Bierbaum VM. Formaldehyde in human cancer cells: detection by preconcentration-chemical ionization mass spectrometry. Analytical Chemistry. 73: 2992-7. PMID 11467545 DOI: 10.1021/Ac001498Q  0.597
2000 Kato S, Burke PJ, Fenick DJ, Taatjes DJ, Bierbaum VM, Koch TH. Mass spectrometric measurement of formaldehyde generated in breast cancer cells upon treatment with anthracycline antitumor drugs. Chemical Research in Toxicology. 13: 509-16. PMID 10858324 DOI: 10.1021/Tx000008M  0.622
1984 Karp JE, Burke PJ, Saylor PL, Humphrey RL. Correlation of Proliferative and Clonogenic Tumor Cells in Multiple Myeloma Cancer Research. 44: 4197-4200. PMID 6744329  0.323
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