Year |
Citation |
Score |
2015 |
Smith CA, Antunes NT, Stewart NK, Frase H, Toth M, Kantardjieff KA, Vakulenko S. Structural Basis for Enhancement of Carbapenemase Activity in the OXA-51 Family of Class D β-Lactamases. Acs Chemical Biology. PMID 26042471 DOI: 10.1021/Acschembio.5B00090 |
0.311 |
|
2015 |
Stewart NK, Smith CA, Frase H, Black DJ, Vakulenko SB. Kinetic and structural requirements for carbapenemase activity in GES-type β-lactamases. Biochemistry. 54: 588-97. PMID 25485972 DOI: 10.1021/Bi501052T |
0.303 |
|
2014 |
Smith CA, Toth M, Weiss TM, Frase H, Vakulenko SB. Structure of the bifunctional aminoglycoside-resistance enzyme AAC(6')-Ie-APH(2'')-Ia revealed by crystallographic and small-angle X-ray scattering analysis. Acta Crystallographica. Section D, Biological Crystallography. 70: 2754-64. PMID 25286858 DOI: 10.1107/S1399004714017635 |
0.308 |
|
2014 |
Smith CA, Toth M, Bhattacharya M, Frase H, Vakulenko SB. Structure of the phosphotransferase domain of the bifunctional aminoglycoside-resistance enzyme AAC(6')-Ie-APH(2'')-Ia. Acta Crystallographica. Section D, Biological Crystallography. 70: 1561-71. PMID 24914967 DOI: 10.1107/S1399004714005331 |
0.403 |
|
2013 |
Toth M, Frase H, Antunes NT, Vakulenko SB. Novel aminoglycoside 2''-phosphotransferase identified in a gram-negative pathogen. Antimicrobial Agents and Chemotherapy. 57: 452-7. PMID 23129050 DOI: 10.1128/AAC.02049-12 |
0.407 |
|
2012 |
Frase H, Toth M, Vakulenko SB. Revisiting the nucleotide and aminoglycoside substrate specificity of the bifunctional aminoglycoside acetyltransferase(6')-Ie/aminoglycoside phosphotransferase(2'')-Ia enzyme. The Journal of Biological Chemistry. 287: 43262-9. PMID 23115238 DOI: 10.1074/jbc.M112.416453 |
0.426 |
|
2012 |
Cheng I, Mikita N, Fishovitz J, Frase H, Wintrode P, Lee I. Identification of a region in the N-terminus of Escherichia coli Lon that affects ATPase, substrate translocation and proteolytic activity. Journal of Molecular Biology. 418: 208-25. PMID 22387465 DOI: 10.1016/J.Jmb.2012.02.039 |
0.591 |
|
2012 |
Smith CA, Toth M, Frase H, Byrnes LJ, Vakulenko SB. Aminoglycoside 2''-phosphotransferase IIIa (APH(2'')-IIIa) prefers GTP over ATP: structural templates for nucleotide recognition in the bacterial aminoglycoside-2'' kinases. The Journal of Biological Chemistry. 287: 12893-903. PMID 22367198 DOI: 10.1074/Jbc.M112.341206 |
0.412 |
|
2011 |
Fishovitz J, Li M, Frase H, Hudak J, Craig S, Ko K, Berdis AJ, Suzuki CK, Lee I. Active-site-directed chemical tools for profiling mitochondrial Lon protease. Acs Chemical Biology. 6: 781-8. PMID 21520912 DOI: 10.1021/Cb100408W |
0.583 |
|
2011 |
Frase H, Smith CA, Toth M, Champion MM, Mobashery S, Vakulenko SB. Identification of products of inhibition of GES-2 beta-lactamase by tazobactam by x-ray crystallography and spectrometry. The Journal of Biological Chemistry. 286: 14396-409. PMID 21345789 DOI: 10.1074/Jbc.M110.208744 |
0.324 |
|
2010 |
Toth M, Frase H, Antunes NT, Smith CA, Vakulenko SB. Crystal structure and kinetic mechanism of aminoglycoside phosphotransferase-2''-IVa. Protein Science : a Publication of the Protein Society. 19: 1565-76. PMID 20556826 DOI: 10.1002/Pro.437 |
0.426 |
|
2010 |
Toth M, Frase H, Chow JW, Smith C, Vakulenko SB. Mutant APH(2'')-IIa enzymes with increased activity against amikacin and isepamicin. Antimicrobial Agents and Chemotherapy. 54: 1590-5. PMID 20145089 DOI: 10.1128/Aac.01444-09 |
0.303 |
|
2009 |
Patterson-Ward J, Tedesco J, Hudak J, Fishovitz J, Becker J, Frase H, McNamara K, Lee I. Utilization of synthetic peptides to evaluate the importance of substrate interaction at the proteolytic site of Escherichia coli Lon protease. Biochimica Et Biophysica Acta. 1794: 1355-63. PMID 19285157 DOI: 10.1016/J.Bbapap.2009.02.015 |
0.616 |
|
2007 |
Frase H, Lee I. Peptidyl boronates inhibit Salmonella enterica serovar Typhimurium Lon protease by a competitive ATP-dependent mechanism. Biochemistry. 46: 6647-57. PMID 17497890 DOI: 10.1021/Bi7002789 |
0.638 |
|
2006 |
Frase H, Hudak J, Lee I. Identification of the proteasome inhibitor MG262 as a potent ATP-dependent inhibitor of the Salmonella enterica serovar Typhimurium Lon protease. Biochemistry. 45: 8264-74. PMID 16819825 DOI: 10.1021/Bi060542E |
0.615 |
|
2005 |
Anderson JL, Frase H, Michaelis S, Hrycyna CA. Purification, functional reconstitution, and characterization of the Saccharomyces cerevisiae isoprenylcysteine carboxylmethyltransferase Ste14p. The Journal of Biological Chemistry. 280: 7336-45. PMID 15611058 DOI: 10.1074/Jbc.M410292200 |
0.336 |
|
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