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Richard W. Lu, Ph.D. - Publications

Affiliations: 
2005 Harvard University, Cambridge, MA, United States 
Area:
Pathology, Molecular Biology
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17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Lu R, Herrera BB, Eshleman HD, Fu Y, Bloom A, Li Z, Sacks DB, Goldberg MB. Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation. Plos Pathogens. 11: e1005200. PMID 26473364 DOI: 10.1371/Journal.Ppat.1005200  0.344
2015 Wang SF, Chang K, Lu RW, Wang WH, Chen YH, Chen M, Wu DC, Chen YM. Large Dengue virus type 1 outbreak in Taiwan. Emerging Microbes & Infections. 4: e46. PMID 26421269 DOI: 10.1038/emi.2015.46  0.322
2015 Johnson S, Eller M, Teigler JE, Maloveste SM, Schultz BT, Soghoian DZ, Lu R, Oster AF, Chenine AL, Alter G, Dittmer U, Marovich M, Robb ML, Michael NL, Bolton D, et al. Cooperativity of HIV-specific cytolytic CD4+ T cells and CD8+ T cells in control of HIV viremia. Journal of Virology. PMID 25972560 DOI: 10.1128/Jvi.00438-15  0.364
2014 Streeck H, Lu R, Beckwith N, Milazzo M, Liu M, Routy JP, Little S, Jessen H, Kelleher AD, Hecht F, Sekaly RP, Alter G, Heckerman D, Carrington M, Rosenberg ES, et al. Emergence of individual HIV-specific CD8 T cell responses during primary HIV-1 infection can determine long-term disease outcome. Journal of Virology. 88: 12793-801. PMID 25165102 DOI: 10.1128/Jvi.02016-14  0.456
2014 Schieffer M, Jessen HK, Oster AF, Pissani F, Soghoian DZ, Lu R, Jessen AB, Zedlack C, Schultz BT, Davis I, Ranasinghe S, Rosenberg ES, Alter G, Schumann RR, Streeck H. Induction of Gag-specific CD4 T cell responses during acute HIV infection is associated with improved viral control. Journal of Virology. 88: 7357-66. PMID 24741089 DOI: 10.1128/Jvi.00728-14  0.453
2013 Ranasinghe S, Cutler S, Davis I, Lu R, Soghoian DZ, Qi Y, Sidney J, Kranias G, Flanders MD, Lindqvist M, Kuhl B, Alter G, Deeks SG, Walker BD, Gao X, et al. Association of HLA-DRB1-restricted CD4⁺ T cell responses with HIV immune control. Nature Medicine. 19: 930-3. PMID 23793098 DOI: 10.1038/Nm.3229  0.421
2009 Belshan M, Schweitzer CJ, Donnellan MR, Lu R, Engelman A. In vivo biotinylation and capture of HIV-1 matrix and integrase proteins. Journal of Virological Methods. 159: 178-84. PMID 19490971 DOI: 10.1016/J.Jviromet.2009.03.017  0.683
2007 Daelemans D, Lu R, De Clercq E, Engelman A. Characterization of a replication-competent, integrase-defective human immunodeficiency virus (HIV)/simian virus 40 chimera as a powerful tool for the discovery and validation of HIV integrase inhibitors. Journal of Virology. 81: 4381-5. PMID 17287285 DOI: 10.1128/Jvi.02637-06  0.69
2007 Rahman S, Lu R, Vandegraaff N, Cherepanov P, Engelman A. Structure-based mutagenesis of the integrase-LEDGF/p75 interface uncouples a strict correlation between in vitro protein binding and HIV-1 fitness. Virology. 357: 79-90. PMID 16959283 DOI: 10.1016/J.Virol.2006.08.011  0.682
2005 Lu R, Vandegraaff N, Cherepanov P, Engelman A. Lys-34, dispensable for integrase catalysis, is required for preintegration complex function and human immunodeficiency virus type 1 replication. Journal of Virology. 79: 12584-91. PMID 16160186 DOI: 10.1128/Jvi.79.19.12584-12591.2005  0.741
2005 Lu R, Ghory HZ, Engelman A. Genetic analyses of conserved residues in the carboxyl-terminal domain of human immunodeficiency virus type 1 integrase. Journal of Virology. 79: 10356-68. PMID 16051828 DOI: 10.1128/Jvi.79.16.10356-10368.2005  0.72
2005 Lu R, Limón A, Ghory HZ, Engelman A. Genetic analyses of DNA-binding mutants in the catalytic core domain of human immunodeficiency virus type 1 integrase. Journal of Virology. 79: 2493-505. PMID 15681450 DOI: 10.1128/Jvi.79.4.2493-2505.2005  0.72
2004 Lu R, Limón A, Devroe E, Silver PA, Cherepanov P, Engelman A. Class II integrase mutants with changes in putative nuclear localization signals are primarily blocked at a postnuclear entry step of human immunodeficiency virus type 1 replication. Journal of Virology. 78: 12735-46. PMID 15542626 DOI: 10.1128/Jvi.78.23.12735-12746.2004  0.715
2004 Lu R, Nakajima N, Hofmann W, Benkirane M, Jeang KT, Sodroski J, Engelman A, Teh-Jeang K. Simian virus 40-based replication of catalytically inactive human immunodeficiency virus type 1 integrase mutants in nonpermissive T cells and monocyte-derived macrophages. Journal of Virology. 78: 658-68. PMID 14694097 DOI: 10.1128/Jvi.78.2.658-668.2004  0.717
2002 Limón A, Nakajima N, Lu R, Ghory HZ, Engelman A. Wild-type levels of nuclear localization and human immunodeficiency virus type 1 replication in the absence of the central DNA flap. Journal of Virology. 76: 12078-86. PMID 12414949 DOI: 10.1128/Jvi.76.23.12078-12086.2002  0.705
2002 Limón A, Devroe E, Lu R, Ghory HZ, Silver PA, Engelman A. Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import. Journal of Virology. 76: 10598-607. PMID 12368302 DOI: 10.1128/Jvi.76.21.10598-10607.2002  0.721
2001 Nakajima N, Lu R, Engelman A. Human immunodeficiency virus type 1 replication in the absence of integrase-mediated DNA recombination: Definition of permissive and nonpermissive T-cell lines Journal of Virology. 75: 7944-7955. PMID 11483739 DOI: 10.1128/Jvi.75.17.7944-7955.2001  0.717
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