Michael J. McConnell - Publications

Affiliations: 
Biochemistry and Molecular Genetics University of Virginia School of Medicine, Charlottesville, VA, United States 
Area:
somatic mosaicism, neuro-immuno development
Website:
http://www.mcconnell-lab.org

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Michel N, Majumdar UB, Lannigan J, McConnell MJ. Imaging Flow Cytometry Quantifies Neural Genome Dynamics. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 31063256 DOI: 10.1002/cyto.a.23783  0.56
2019 Chronister WD, Burbulis IE, Wierman MB, Wolpert MJ, Haakenson MF, Smith ACB, Kleinman JE, Hyde TM, Weinberger DR, Bekiranov S, McConnell MJ. Neurons with Complex Karyotypes Are Rare in Aged Human Neocortex. Cell Reports. 26: 825-835.e7. PMID 30673605 DOI: 10.1016/j.celrep.2018.12.107  1
2018 Harbom LJ, Rudisill TL, Michel N, Litwa KA, Beenhakker MP, McConnell MJ. The effect of rho kinase inhibition on morphological and electrophysiological maturity in iPSC-derived neurons. Cell and Tissue Research. PMID 30406823 DOI: 10.1007/s00441-018-2942-7  1
2017 Harbom LJ, Michel N, McConnell MJ. Single-cell analysis of diversity in human stem cell-derived neurons. Cell and Tissue Research. PMID 29185070 DOI: 10.1007/s00441-017-2728-3  1
2017 McConnell MJ, Moran JV, Abyzov A, Akbarian S, Bae T, Cortes-Ciriano I, Erwin JA, Fasching L, Flasch DA, Freed D, Ganz J, Jaffe AE, Kwan KY, Kwon M, Lodato MA, et al. Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network. Science (New York, N.Y.). 356. PMID 28450582 DOI: 10.1126/science.aal1641  0.96
2017 Lacar B, Linker SB, Jaeger BN, Krishnaswami SR, Barron JJ, Kelder MJ, Parylak SL, Paquola AC, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin JA, Hsu JY, Husband D, ... McConnell MJ, et al. Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nature Communications. 8: 15047. PMID 28303884 DOI: 10.1038/ncomms15047  0.96
2016 Fields FR, Lee SW, McConnell MJ. Using Bacterial Genomes and Essential Genes for the Development of New Antibiotics. Biochemical Pharmacology. PMID 27940263 DOI: 10.1016/j.bcp.2016.12.002  0.48
2016 Lacar B, Linker SB, Jaeger BN, Krishnaswami SR, Barron JJ, Kelder MJ, Parylak SL, Paquola AC, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin JA, Hsu JY, Husband D, ... McConnell MJ, et al. Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nature Communications. 7: 12020. PMID 27295945 DOI: 10.1038/ncomms12020  0.96
2016 Lacar B, Linker SB, Jaeger BN, Krishnaswami S, Barron J, Kelder M, Parylak S, Paquola A, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin J, Hsu JY, Husband D, ... McConnell MJ, et al. Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nature Communications. 7: 11022. PMID 27090946 DOI: 10.1038/ncomms11022  0.96
2016 Krishnaswami SR, Grindberg RV, Novotny M, Venepally P, Lacar B, Bhutani K, Linker SB, Pham S, Erwin JA, Miller JA, Hodge R, McCarthy JK, Kelder M, McCorrison J, Aevermann BD, ... ... McConnell MJ, et al. Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons. Nature Protocols. 11: 499-524. PMID 26890679 DOI: 10.1038/nprot.2016.015  1
2016 Harbom LJ, Chronister WD, McConnell MJ. Single neuron transcriptome analysis can reveal more than cell type classification: Does it matter if every neuron is unique? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 26749010 DOI: 10.1002/bies.201500097  1
2015 Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, et al. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports. PMID 26610635 DOI: 10.1016/j.stemcr.2015.10.011  0.96
2013 Grindberg RV, Yee-Greenbaum JL, McConnell MJ, Novotny M, O'Shaughnessy AL, Lambert GM, Araúzo-Bravo MJ, Lee J, Fishman M, Robbins GE, Lin X, Venepally P, Badger JH, Galbraith DW, Gage FH, et al. RNA-sequencing from single nuclei. Proceedings of the National Academy of Sciences of the United States of America. 110: 19802-7. PMID 24248345 DOI: 10.1073/pnas.1319700110  0.96
2013 McConnell MJ, Lindberg MR, Brennand KJ, Piper JC, Voet T, Cowing-Zitron C, Shumilina S, Lasken RS, Vermeesch JR, Hall IM, Gage FH. Mosaic copy number variation in human neurons. Science (New York, N.Y.). 342: 632-7. PMID 24179226 DOI: 10.1126/science.1243472  0.96
2013 McConnell MJ, Gage FH. Neuronal Genomic and Epigenetic Diversity Epigenetic Regulation in the Nervous System. 281-298. DOI: 10.1016/B978-0-12-391494-1.00011-2  0.96
2011 MacMillan HR, McConnell MJ. Seeing beyond the average cell: branching process models of cell proliferation, differentiation, and death during mouse brain development. Theory in Biosciences = Theorie in Den Biowissenschaften. 130: 31-43. PMID 20824512 DOI: 10.1007/s12064-010-0107-7  0.96
2010 Singer T, McConnell MJ, Marchetto MC, Coufal NG, Gage FH. LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes? Trends in Neurosciences. 33: 345-54. PMID 20471112 DOI: 10.1016/j.tins.2010.04.001  0.96
2010 Sartore RC, Campos PB, McConnell MJ, Rehen SK. Aneuploidy in embryonic stem cells Perspectives of Stem Cells: From Tools For Studying Mechanisms of Neuronal Differentiation Towards Therapy. 73-86. DOI: 10.1007/978-90-481-3375-8_6  0.96
2009 Datwani A, McConnell MJ, Kanold PO, Micheva KD, Busse B, Shamloo M, Smith SJ, Shatz CJ. Classical MHCI molecules regulate retinogeniculate refinement and limit ocular dominance plasticity. Neuron. 64: 463-70. PMID 19945389 DOI: 10.1016/j.neuron.2009.10.015  0.56
2009 McConnell MJ, MacMillan HR, Chun J. Mathematical modeling supports substantial mouse neural progenitor cell death. Neural Development. 4: 28. PMID 19602274 DOI: 10.1186/1749-8104-4-28  0.96
2009 McConnell MJ, Huang YH, Datwani A, Shatz CJ. H2-K(b) and H2-D(b) regulate cerebellar long-term depression and limit motor learning. Proceedings of the National Academy of Sciences of the United States of America. 106: 6784-9. PMID 19346486 DOI: 10.1073/pnas.0902018106  0.56
2005 Kingsbury MA, Friedman B, McConnell MJ, Rehen SK, Yang AH, Kaushal D, Chun J. Aneuploid neurons are functionally active and integrated into brain circuitry. Proceedings of the National Academy of Sciences of the United States of America. 102: 6143-7. PMID 15837924 DOI: 10.1073/pnas.0408171102  0.96
2005 Rehen SK, Yung YC, McCreight MP, Kaushal D, Yang AH, Almeida BS, Kingsbury MA, Cabral KM, McConnell MJ, Anliker B, Fontanoz M, Chun J. Constitutional aneuploidy in the normal human brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2176-80. PMID 15745943 DOI: 10.1523/JNEUROSCI.4560-04.2005  0.96
2004 McConnell MJ, Kaushal D, Yang AH, Kingsbury MA, Rehen SK, Treuner K, Helton R, Annas EG, Chun J, Barlow C. Failed clearance of aneuploid embryonic neural progenitor cells leads to excess aneuploidy in the Atm-deficient but not the Trp53-deficient adult cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8090-6. PMID 15371510 DOI: 10.1523/JNEUROSCI.2263-04.2004  0.96
2003 Yang AH, Kaushal D, Rehen SK, Kriedt K, Kingsbury MA, McConnell MJ, Chun J. Chromosome segregation defects contribute to aneuploidy in normal neural progenitor cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10454-62. PMID 14614104  0.96
2003 Kaushal D, Contos JJ, Treuner K, Yang AH, Kingsbury MA, Rehen SK, McConnell MJ, Okabe M, Barlow C, Chun J. Alteration of gene expression by chromosome loss in the postnatal mouse brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5599-606. PMID 12843262  0.96
2003 Zhao X, Ueba T, Christie BR, Barkho B, McConnell MJ, Nakashima K, Lein ES, Eadie BD, Willhoite AR, Muotri AR, Summers RG, Chun J, Lee KF, Gage FH. Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function. Proceedings of the National Academy of Sciences of the United States of America. 100: 6777-82. PMID 12748381 DOI: 10.1073/pnas.1131928100  0.96
2001 Rehen SK, McConnell MJ, Kaushal D, Kingsbury MA, Yang AH, Chun J. Chromosomal variation in neurons of the developing and adult mammalian nervous system. Proceedings of the National Academy of Sciences of the United States of America. 98: 13361-6. PMID 11698687 DOI: 10.1073/pnas.231487398  0.96
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