| Year |
Citation |
Score |
| 2019 |
Forero A, Ozarkar S, Li H, Lee CH, Hemann EA, Nadjsombati MS, Hendricks MR, So L, Green R, Roy CN, Sarkar SN, von Moltke J, Anderson SK, Gale M, Savan R. Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and III Interferons. Immunity. PMID 31471108 DOI: 10.1016/J.Immuni.2019.07.007 |
0.383 |
|
| 2019 |
Rivadeneira DB, DePeaux K, Wang Y, Kulkarni A, Tabib T, Menk AV, Sampath P, Lafyatis R, Ferris RL, Sarkar SN, Thorne SH, Delgoffe GM. Oncolytic Viruses Engineered to Enforce Leptin Expression Reprogram Tumor-Infiltrating T Cell Metabolism and Promote Tumor Clearance. Immunity. PMID 31471106 DOI: 10.1016/J.Immuni.2019.07.003 |
0.328 |
|
| 2019 |
Barroso-González J, García-Expósito L, Hoang SM, Lynskey ML, Roncaioli JL, Ghosh A, Wallace CT, Modesti M, Bernstein KA, Sarkar SN, Watkins SC, O'Sullivan RJ. RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres. Molecular Cell. PMID 31400850 DOI: 10.1016/J.Molcel.2019.06.043 |
0.319 |
|
| 2019 |
Zhang T, Sarkar SN, Zhu J. Molecular Cloning and Functional Characterization of Mouse Innate Immune Sensor RIG-I Cytology and Genetics. 53: 325-329. DOI: 10.3103/S0095452719040121 |
0.392 |
|
| 2018 |
Ghosh A, Shao L, Sampath P, Zhao B, Patel NV, Zhu J, Behl B, Parise RA, Beumer JH, O'Sullivan RJ, DeLuca NA, Thorne SH, Rathinam VAK, Li P, Sarkar SN. Oligoadenylate-Synthetase-Family Protein OASL Inhibits Activity of the DNA Sensor cGAS during DNA Virus Infection to Limit Interferon Production. Immunity. PMID 30635239 DOI: 10.1016/J.Immuni.2018.12.013 |
0.389 |
|
| 2018 |
Gregg RW, Sarkar SN, Shoemaker JE. Mathematical Modeling of the cGAS Pathway Reveals Robustness of DNA Sensing to TREX1 Feedback. Journal of Theoretical Biology. PMID 30395807 DOI: 10.1016/J.Jtbi.2018.11.001 |
0.326 |
|
| 2018 |
Banerjee I, Behl B, Mendonca M, Shrivastava G, Russo AJ, Menoret A, Ghosh A, Vella AT, Vanaja SK, Sarkar SN, Fitzgerald KA, Rathinam VAK. Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis. Immunity. PMID 30170814 DOI: 10.1016/J.Immuni.2018.07.006 |
0.301 |
|
| 2018 |
Theodoraki MN, Yerneni S, Sarkar SN, Orr B, Muthuswamy R, Voyten J, Modugno F, Jiang W, Grimm M, Basse PH, Bartlett DL, Edwards R, Kalinski P. Helicase-driven activation of NFκB-COX2 mediates the immunosuppressive component of dsRNA-driven inflammation in the human tumor microenvironment. Cancer Research. PMID 29853604 DOI: 10.1158/0008-5472.Can-17-3985 |
0.42 |
|
| 2016 |
Cuevas RA, Ghosh A, Wallerath C, Hornung V, Coyne CB, Sarkar SN. MOV10 Provides Antiviral Activity against RNA Viruses by Enhancing RIG-I-MAVS-Independent IFN Induction. Journal of Immunology (Baltimore, Md. : 1950). PMID 27016603 DOI: 10.4049/Jimmunol.1501359 |
0.437 |
|
| 2016 |
McCormick KD, Ghosh A, Trivedi S, Wang L, Coyne CB, Ferris RL, Sarkar SN. Innate immune signaling through differential RIPK1 expression promote tumor progression in head and neck squamous cell carcinoma. Carcinogenesis. PMID 26992898 DOI: 10.1093/Carcin/Bgw032 |
0.388 |
|
| 2016 |
Hendricks MR, Lashua LP, Fischer DK, Flitter BA, Eichinger KM, Durbin JE, Sarkar SN, Coyne CB, Empey KM, Bomberger JM. Respiratory syncytial virus infection enhances Pseudomonas aeruginosa biofilm growth through dysregulation of nutritional immunity. Proceedings of the National Academy of Sciences of the United States of America. PMID 26729873 DOI: 10.1073/Pnas.1516979113 |
0.305 |
|
| 2015 |
Shu Q, Lennemann NJ, Sarkar SN, Sadovsky Y, Coyne CB. ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry. Plos Pathogens. 11: e1005150. PMID 26372645 DOI: 10.1371/Journal.Ppat.1005150 |
0.389 |
|
| 2015 |
Dhar J, Cuevas RA, Goswami R, Zhu J, Sarkar SN, Barik S. 2' -5' -Oligoadenylate Synthetase-Like Inhibits Respiratory Syncytial Virus Replication and is Targeted by the Viral Nonstructural Protein 1. Journal of Virology. PMID 26178980 DOI: 10.1128/Jvi.01076-15 |
0.384 |
|
| 2015 |
Ibsen MS, Gad HH, Andersen LL, Hornung V, Julkunen I, Sarkar SN, Hartmann R. Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling. Nucleic Acids Research. 43: 5236-48. PMID 25925578 DOI: 10.1093/Nar/Gkv389 |
0.362 |
|
| 2015 |
Zhu J, Ghosh A, Sarkar SN. OASL-a new player in controlling antiviral innate immunity. Current Opinion in Virology. 12: 15-19. PMID 25676874 DOI: 10.1016/J.Coviro.2015.01.010 |
0.353 |
|
| 2015 |
Alcorn JF, Sarkar SN. What is the oligoadenylate synthetases-like protein and does it have therapeutic potential for influenza? Expert Review of Respiratory Medicine. 9: 1-3. PMID 25544107 DOI: 10.1586/17476348.2015.994608 |
0.322 |
|
| 2014 |
Sarkar SN. Could boosting the oligoadenylate synthetase-like pathway bring a new era of antiviral therapy? Future Virology. 9: 1011-1014. PMID 25620998 DOI: 10.2217/Fvl.14.81 |
0.369 |
|
| 2014 |
Ohkuri T, Ghosh A, Kosaka A, Zhu J, Ikeura M, David M, Watkins SC, Sarkar SN, Okada H. STING contributes to antiglioma immunity via triggering type I IFN signals in the tumor microenvironment. Cancer Immunology Research. 2: 1199-208. PMID 25300859 DOI: 10.1158/2326-6066.Cir-14-0099 |
0.366 |
|
| 2014 |
Yang S, Deng P, Zhu Z, Zhu J, Wang G, Zhang L, Chen AF, Wang T, Sarkar SN, Billiar TR, Wang Q. Adenosine deaminase acting on RNA 1 limits RIG-I RNA detection and suppresses IFN production responding to viral and endogenous RNAs. Journal of Immunology (Baltimore, Md. : 1950). 193: 3436-45. PMID 25172485 DOI: 10.4049/Jimmunol.1401136 |
0.363 |
|
| 2014 |
Zhu J, Zhang Y, Ghosh A, Cuevas RA, Forero A, Dhar J, Ibsen MS, Schmid-Burgk JL, Schmidt T, Ganapathiraju MK, Fujita T, Hartmann R, Barik S, Hornung V, Coyne CB, ... Sarkar SN, et al. Antiviral activity of human OASL protein is mediated by enhancing signaling of the RIG-I RNA sensor. Immunity. 40: 936-48. PMID 24931123 DOI: 10.1016/J.Immuni.2014.05.007 |
0.457 |
|
| 2014 |
Forero A, McCormick KD, Jenkins FJ, Sarkar SN. Downregulation of IRF4 induces lytic reactivation of KSHV in primary effusion lymphoma cells. Virology. 458: 4-10. PMID 24928034 DOI: 10.1016/J.Virol.2014.04.020 |
0.376 |
|
| 2014 |
Forero A, Giacobbi NS, McCormick KD, Gjoerup OV, Bakkenist CJ, Pipas JM, Sarkar SN. Simian virus 40 large T antigen induces IFN-stimulated genes through ATR kinase. Journal of Immunology (Baltimore, Md. : 1950). 192: 5933-42. PMID 24799566 DOI: 10.4049/Jimmunol.1303470 |
0.432 |
|
| 2014 |
Jacobs JL, Zhu J, Sarkar SN, Coyne CB. Regulation of mitochondrial antiviral signaling (MAVS) expression and signaling by the mitochondria-associated endoplasmic reticulum membrane (MAM) protein Gp78. The Journal of Biological Chemistry. 289: 1604-16. PMID 24285545 DOI: 10.1074/Jbc.M113.520254 |
0.338 |
|
| 2014 |
Ohkuri T, Ghosh A, Kosaka A, Zhu J, Ikeura M, David M, Watkins SC, Sarkar SN, Okada H. STING contributes to anti-glioma immunity via triggering type-I IFN signals in the tumor microenvironment Journal For Immunotherapy of Cancer. 2: 228. DOI: 10.1186/2051-1426-2-S3-P228 |
0.353 |
|
| 2014 |
Ohkuri T, Ghosh A, Kosaka A, Zhu J, Ikeura M, David M, Watkins S, Sarkar S, Okada H. Ib-09Sting Agonist Induces Potent Anti-Glioma Immunity Via Induction Of Type-I Ifn Signals In The Tumor Microenvironment Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou257.9 |
0.37 |
|
| 2013 |
Forero A, Moore PS, Sarkar SN. Role of IRF4 in IFN-stimulated gene induction and maintenance of Kaposi sarcoma-associated herpesvirus latency in primary effusion lymphoma cells. Journal of Immunology (Baltimore, Md. : 1950). 191: 1476-85. PMID 23804715 DOI: 10.4049/Jimmunol.1202514 |
0.419 |
|
| 2013 |
Okada H, Scheurer ME, Sarkar SN, Bondy ML. Integration of epidemiology, immunobiology, and translational research for brain tumors. Annals of the New York Academy of Sciences. 1284: 17-23. PMID 23651189 DOI: 10.1111/Nyas.12115 |
0.317 |
|
| 2013 |
Zhu J, Ghosh A, Coyle EM, Lee J, Hahm ER, Singh SV, Sarkar SN. Differential effects of phenethyl isothiocyanate and D,L-sulforaphane on TLR3 signaling. Journal of Immunology (Baltimore, Md. : 1950). 190: 4400-7. PMID 23509350 DOI: 10.4049/Jimmunol.1202093 |
0.394 |
|
| 2012 |
Bozym RA, Delorme-Axford E, Harris K, Morosky S, Ikizler M, Dermody TS, Sarkar SN, Coyne CB. Focal adhesion kinase is a component of antiviral RIG-I-like receptor signaling. Cell Host & Microbe. 11: 153-66. PMID 22341464 DOI: 10.1016/J.Chom.2012.01.008 |
0.377 |
|
| 2012 |
Umemura N, Zhu J, Mburu YK, Forero A, Hsieh PN, Muthuswamy R, Kalinski P, Ferris RL, Sarkar SN. Defective NF-κB signaling in metastatic head and neck cancer cells leads to enhanced apoptosis by double-stranded RNA. Cancer Research. 72: 45-55. PMID 22058147 DOI: 10.1158/0008-5472.Can-11-1484 |
0.395 |
|
| 2012 |
Kohanbash G, Ishikawa E, Fujita M, Mckaveney K, Sakaki M, Scheurer M, Bondy M, Sarkar SN, Okada H. Abstract 1246: ELK-1 regulates interferon-alpha8 expression via a polymorphic region in the interferon-alpha8 promoter associated with outcome of glioma patients Cancer Research. 72: 1246-1246. DOI: 10.1158/1538-7445.Am2012-1246 |
0.357 |
|
| 2011 |
Zhu J, Coyne CB, Sarkar SN. PKC alpha regulates Sendai virus-mediated interferon induction through HDAC6 and β-catenin. The Embo Journal. 30: 4838-49. PMID 21952047 DOI: 10.1038/Emboj.2011.351 |
0.406 |
|
| 2011 |
Morosky SA, Zhu J, Mukherjee A, Sarkar SN, Coyne CB. Retinoic acid-induced gene-I (RIG-I) associates with nucleotide-binding oligomerization domain-2 (NOD2) to negatively regulate inflammatory signaling. The Journal of Biological Chemistry. 286: 28574-83. PMID 21690088 DOI: 10.1074/Jbc.M111.227942 |
0.407 |
|
| 2011 |
Mburu YK, Abe K, Ferris LK, Sarkar SN, Ferris RL. Human β-defensin 3 promotes NF-κB-mediated CCR7 expression and anti-apoptotic signals in squamous cell carcinoma of the head and neck. Carcinogenesis. 32: 168-74. PMID 21071608 DOI: 10.1093/Carcin/Bgq236 |
0.376 |
|
| 2010 |
Rathi AV, Cantalupo PG, Sarkar SN, Pipas JM. Induction of interferon-stimulated genes by Simian virus 40 T antigens. Virology. 406: 202-11. PMID 20692676 DOI: 10.1016/J.Virol.2010.07.018 |
0.381 |
|
| 2010 |
Zhu J, Smith K, Hsieh PN, Mburu YK, Chattopadhyay S, Sen GC, Sarkar SN. High-throughput screening for TLR3-IFN regulatory factor 3 signaling pathway modulators identifies several antipsychotic drugs as TLR inhibitors Journal of Immunology. 184: 5768-5776. PMID 20382888 DOI: 10.4049/Jimmunol.0903559 |
0.389 |
|
| 2010 |
Beura LK, Sarkar SN, Kwon B, Subramaniam S, Jones C, Pattnaik AK, Osorio FA. Porcine reproductive and respiratory syndrome virus nonstructural protein 1beta modulates host innate immune response by antagonizing IRF3 activation. Journal of Virology. 84: 1574-84. PMID 19923190 DOI: 10.1128/Jvi.01326-09 |
0.427 |
|
| 2008 |
Hartmann R, Justesen J, Sarkar S, Sen G, Yee V. Crystal Structure of the 2′‐Specific and Double‐Stranded RNA‐Activated Interferon‐Induced Antiviral Protein 2′‐5′‐Oligoadenylate Synthetase Scandinavian Journal of Immunology. 59: 617-617. DOI: 10.1111/J.0300-9475.2004.01423S.X |
0.357 |
|
| 2007 |
Sen GC, Sarkar SN. The interferon-stimulated genes: Targets of direct signaling by interferons, double-stranded RNA, and viruses Current Topics in Microbiology and Immunology. 316: 233-250. PMID 17969451 DOI: 10.1007/978-3-540-71329-6_12 |
0.404 |
|
| 2007 |
Sarkar SN, Elco CP, Peters KL, Chattopadhyay S, Sen GC. Two tyrosine residues of Toll-like receptor 3 trigger different steps of NF-kappa B activation. The Journal of Biological Chemistry. 282: 3423-7. PMID 17178723 DOI: 10.1074/Jbc.C600226200 |
0.391 |
|
| 2005 |
Sen GC, Sarkar SN. Hitching RIG to action. Nature Immunology. 6: 1074-6. PMID 16239922 DOI: 10.1038/Ni1105-1074 |
0.323 |
|
| 2005 |
Sarkar SN, Pandey M, Sen GC. Assays for the interferon-induced enzyme 2',5' oligoadenylate synthetases. Methods in Molecular Medicine. 116: 81-101. PMID 16000856 DOI: 10.1385/1-59259-939-7:081 |
0.381 |
|
| 2005 |
Sarkar SN, Kessler SP, Rowe TM, Pandey M, Ghosh A, Elco CP, Hartmann R, Pal S, Sen GC. Natural mutations in a 2'-5' oligoadenylate synthetase transgene revealed residues essential for enzyme activity. Biochemistry. 44: 6837-43. PMID 15865429 DOI: 10.1021/Bi0502893 |
0.342 |
|
| 2005 |
Sen GC, Sarkar SN. Transcriptional signaling by double-stranded RNA: role of TLR3. Cytokine & Growth Factor Reviews. 16: 1-14. PMID 15733829 DOI: 10.1016/J.Cytogfr.2005.01.006 |
0.442 |
|
| 2004 |
Sarkar SN, Peters KL, Elco CP, Sakamoto S, Pal S, Sen GC. Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling. Nature Structural & Molecular Biology. 11: 1060-7. PMID 15502848 DOI: 10.1038/Nsmb847 |
0.391 |
|
| 2004 |
Sarkar SN, Sen GC. Novel functions of proteins encoded by viral stress-inducible genes. Pharmacology & Therapeutics. 103: 245-59. PMID 15464592 DOI: 10.1016/J.Pharmthera.2004.07.007 |
0.414 |
|
| 2003 |
Hartmann R, Justesen J, Sarkar SN, Sen GC, Yee VC. Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase. Molecular Cell. 12: 1173-85. PMID 14636576 DOI: 10.1016/S1097-2765(03)00433-7 |
0.369 |
|
| 2003 |
Sarkar SN, Smith HL, Rowe TM, Sen GC. Double-stranded RNA signaling by Toll-like receptor 3 requires specific tyrosine residues in its cytoplasmic domain. The Journal of Biological Chemistry. 278: 4393-6. PMID 12509442 DOI: 10.1074/Jbc.C200655200 |
0.425 |
|
| 2002 |
Sarkar SN, Pal S, Sen GC. Crisscross enzymatic reaction between the two molecules in the active dimeric P69 form of the 2'-5' oligodenylate synthetase. The Journal of Biological Chemistry. 277: 44760-4. PMID 12223486 DOI: 10.1074/Jbc.M207126200 |
0.314 |
|
| 2001 |
Ghosh A, Sarkar SN, Rowe TM, Sen GC. A Specific Isozyme of 2′-5′ Oligoadenylate Synthetase is a Dual Function Proapoptotic Protein of the Bcl-2 Family Journal of Biological Chemistry. 276: 25447-25455. PMID 11323417 DOI: 10.1074/Jbc.M100496200 |
0.357 |
|
| 2000 |
Ghosh A, Sarkar SN, Sen GC. Cell growth regulatory and antiviral effects of the P69 isozyme of 2-5 (A) synthetase Virology. 266: 319-328. PMID 10639318 DOI: 10.1006/Viro.1999.0085 |
0.342 |
|
| 1999 |
Sarkar SN, Ghosh A, Wang HW, Sung SS, Sen GC. The nature of the catalytic domain of 2'-5'-oligoadenylate synthetases Journal of Biological Chemistry. 274: 25535-25542. PMID 10464285 DOI: 10.1074/Jbc.274.36.25535 |
0.306 |
|
| 1999 |
Sarkar SN, Bandyopadhyay S, Ghosh A, Sen GC. Enzymatic characteristics of recombinant medium isozyme of 2'-5' oligoadenylate synthetase Journal of Biological Chemistry. 274: 1848-1855. PMID 9880569 DOI: 10.1074/Jbc.274.3.1848 |
0.353 |
|
| 1998 |
Sarkar SN, Sen GC. Production, Purification, and Characterization of Recombinant 2′,5′-Oligoadenylate Synthetases Methods. 15: 233-242. PMID 9735308 DOI: 10.1006/Meth.1998.0627 |
0.379 |
|
| 1998 |
Bandyopadhyay S, Ghosh A, Sarkar SN, Sen GC. Production and purification of recombinant 2'-5' oligoadenylate synthetase and its mutants using the baculovirus system Biochemistry. 37: 3824-3830. PMID 9521702 DOI: 10.1021/Bi972848E |
0.367 |
|
| 1997 |
Ghosh A, Sarkar SN, Guo W, Bandyopadhyay S, Sen GC. Enzymatic activity of 2'-5'-oligoadenylate synthetase is impaired by specific mutations that affect oligomerization of the protein Journal of Biological Chemistry. 272: 33220-33226. PMID 9407111 DOI: 10.1074/Jbc.272.52.33220 |
0.342 |
|
| 1997 |
Ghosh A, Desai SY, Sarkar SN, Ramaraj P, Ghosh SK, Bandyopadhyay S, Sen GC. Effects of mutating specific residues present near the amino terminus of 2'-5'-oligoadenylate synthetase Journal of Biological Chemistry. 272: 15452-15458. PMID 9182577 DOI: 10.1074/Jbc.272.24.15452 |
0.338 |
|
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