Scott E. Plevy - Publications

Affiliations: 
Microbiology & Immunology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Immunology, Microbiology Biology

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Torres J, Petralia F, Sato T, Wang P, Telesco SE, Choung RS, Strauss R, Li XJ, Laird RM, Gutierrez RL, Porter CK, Plevy S, Princen F, Murray JA, Riddle MS, et al. Serum Biomarkers Identify Patients Who Will Develop Inflammatory Bowel Diseases Up to 5 y Before Diagnosis. Gastroenterology. PMID 32165208 DOI: 10.1053/J.Gastro.2020.03.007  0.346
2019 Erturk-Hasdemir D, Oh SF, Okan NA, Stefanetti G, Gazzaniga FS, Seeberger PH, Plevy SE, Kasper DL. Symbionts exploit complex signaling to educate the immune system. Proceedings of the National Academy of Sciences of the United States of America. PMID 31811024 DOI: 10.1073/Pnas.1915978116  0.361
2019 Manthey CL, Moore BA, Chen Y, Loza MJ, Yao X, Liu H, Belkowski SM, Raymond-Parks H, Dunford PJ, Leon F, Towne JE, Plevy SE. The CSF-1-receptor inhibitor, JNJ-40346527 (PRV-6527), reduced inflammatory macrophage recruitment to the intestinal mucosa and suppressed murine T cell mediated colitis. Plos One. 14: e0223918. PMID 31710624 DOI: 10.1371/Journal.Pone.0223918  0.383
2019 Oka A, Mishima Y, Liu B, Herzog JW, Steinbach EC, Kobayashi T, Plevy SE, Sartor RB. Phosphoinositide 3-Kinase P110δ-Signaling Is Critical for Microbiota-Activated IL-10 Production by B Cells that Regulate Intestinal Inflammation. Cells. 8. PMID 31546615 DOI: 10.3390/Cells8101121  0.787
2019 Ellermann M, Gharaibeh RZ, Maharshak N, Peréz-Chanona E, Jobin C, Carroll IM, Arthur JC, Plevy SE, Fodor AA, Brouwer CR, Sartor RB. Dietary iron variably modulates assembly of the intestinal microbiota in colitis-resistant and colitis-susceptible mice. Gut Microbes. 1-19. PMID 31179826 DOI: 10.1080/19490976.2019.1599794  0.314
2019 Contijoch EJ, Britton GJ, Yang C, Mogno I, Li Z, Ng R, Llewellyn SR, Hira S, Johnson C, Rabinowitz KM, Barkan R, Dotan I, Hirten RP, Fu SC, Luo Y, ... ... Plevy S, et al. Gut microbiota density influences host physiology and is shaped by host and microbial factors. Elife. 8. PMID 30666957 DOI: 10.7554/Elife.40553  0.322
2019 Choung RS, Petralia F, Torres J, Sato T, Li X, Wang P, Telesco S, Porter C, Laird R, Gutierrez R, Princen F, Plevy S, Strauss R, Riddle M, Murray J, et al. DOP35 Innate immune dysregulation, detectable up to 6 years before the diagnosis of Crohn’s disease, is significantly amplified in patients with a complicated phenotype Journal of Crohns & Colitis. 13. DOI: 10.1093/Ecco-Jcc/Jjy222.069  0.323
2019 Sato T, Li K, Hayden K, Tomsho L, Baribaud F, Brodmerkel C, Greenbaum LE, Friedman JR, Curran M, Imai Y, Plevy S, Telesco SE. OP36 A colonic gene expression signature predicts non-response to anti-inflammatory therapies in inflammatory bowel disease Journal of Crohn's and Colitis. 13: S025-S025. DOI: 10.1093/Ecco-Jcc/Jjy222.033  0.368
2019 Choung RS, Petralia F, Torres J, Sato T, Li X, Wang P, Telesco S, Porter CK, Laird R, Gutierrez R, Princen F, Plevy S, Strauss R, Riddle MS, Murray JA, et al. Sa1818 – Innate Immune Dysregulation, Detectable Up to 6 Years Before the Diagnosis of Crohn's Disease, is Significantly Amplified in Patients with a Complicated Phenotype Gastroenterology. 156: S-413-S-414. DOI: 10.1016/S0016-5085(19)37885-0  0.33
2018 Hall AO, Towne JE, Plevy SE. Get the IL-17F outta here! Nature Immunology. PMID 29915294 DOI: 10.1038/S41590-018-0141-Z  0.382
2018 Lin X, Lofland J, Zhang L, Lee K, Sloan S, Chamaa L, Marano C, Plevy S. P715 Opioid use in patients with inflammatory bowel disease Journal of Crohn's and Colitis. 12: S473-S473. DOI: 10.1093/Ecco-Jcc/Jjx180.842  0.336
2018 Kosoy R, Kim-Schulze S, Rahman A, Peters L, El-ad A, Perrigoue J, Castillo A, Rogers J, Atreja A, Hurley A, Merad M, Colombel JF, Dubinsky M, Friedman JR, Brodmerkel C, ... Plevy S, et al. P013 Immunophenotyping of peripheral whole blood from 743 IBD patients identifies patterns of association between immune cell populations and T-cell subsets with disease occurrence, severity and medication use Journal of Crohn's and Colitis. 12: S098-S098. DOI: 10.1093/Ecco-Jcc/Jjx180.140  0.311
2018 Oka A, Mishima Y, Bongers G, Liu B, Herzog J, Baltus A, Marshall D, Hesse M, Atarashi K, Fukuda S, Honda K, Mateo LS, Plevy S, Sartor RB. Tu1844 - IL-10-Independent Protective Activities of Human-Derived Clostridium Strains in Experimental Colitis Gastroenterology. 154: S-1036. DOI: 10.1016/S0016-5085(18)33470-X  0.351
2018 Lin X, Lofland J, Zhang L, Lee K, Sloan S, Chamaa L, Marano C, Plevy S. Sa1811 - Opioid use in Patients with Inflammatory Bowel Disease Gastroenterology. 154: S-404. DOI: 10.1016/S0016-5085(18)31635-4  0.335
2018 Kosoy R, Kim-Schulze S, Rahman A, Peters LA, Amir E, Perrigoue J, Castillo A, Rogers J, Atreja A, Hurley A, merad m, Colombel JF, Dubinsky M, Friedman JR, Brodmerkel C, ... Plevy S, et al. 1009 - Immunophenotyping of Peripheral Whole Blood from 743 IBD Patients Identifies Patterns of Association Between Immune Cell Populations and T-Cell Subsets with Disease Occurrence, Severity and Medication Use Gastroenterology. 154: S-190. DOI: 10.1016/S0016-5085(18)31041-2  0.306
2017 West NR, Hegazy AN, Owens BMJ, Bullers SJ, Linggi B, Buonocore S, Coccia M, Görtz D, This S, Stockenhuber K, Pott J, Friedrich M, Ryzhakov G, Baribaud F, Brodmerkel C, ... ... Plevy SE, et al. Erratum: Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease. Nature Medicine. 23: 788. PMID 28586341 DOI: 10.1038/Nm0617-788D  0.366
2017 West NR, Hegazy AN, Owens BM, Bullers SJ, Linggi B, Buonocore S, Coccia M, Görtz D, This S, Stockenhuber K, Pott J, Friedrich M, Ryzhakov G, Baribaud F, Brodmerkel C, ... ... Plevy SE, et al. Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease. Nature Medicine. PMID 28368383 DOI: 10.1038/Nm.4307  0.446
2017 Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP. NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth. Nature Immunology. PMID 28288099 DOI: 10.1038/Ni.3690  0.461
2017 Hegazy A, West N, Owens B, Bullers S, Linggi B, Buonocore S, Coccia M, Görtz D, This S, Stockenhuber K, Pott J, Friedrich M, Ryzhakov G, Baribaud F, Brodmerkel C, ... ... Plevy S, et al. Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease Viszeralmedizin. DOI: 10.1055/S-0037-1604794  0.364
2015 Shailubhai K, Palejwala V, Arjunan KP, Saykhedkar S, Nefsky B, Foss JA, Comiskey S, Jacob GS, Plevy SE. Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis. World Journal of Gastrointestinal Pharmacology and Therapeutics. 6: 213-22. PMID 26558155 DOI: 10.4292/Wjgpt.V6.I4.213  0.361
2015 Maharshak N, Ryu HS, Fan TJ, Onyiah JC, Schulz S, Otterbein SL, Wong R, Hansen J, Otterbein L, Carroll I, Plevy SE. Escherichia coli heme oxygenase modulates host innate immune responses. Microbiology and Immunology. PMID 26146866 DOI: 10.1111/1348-0421.12282  0.418
2014 Hughes JT, Herfarth HH, Isaacs KL, Plevy SE, Sartor RB, Sheikh SZ, Hansen JJ, Long MD. Infliximab Re-treatment in Inflammatory Bowel Disease: A Single-Center Routine Clinical Experience. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 24835819 DOI: 10.1016/J.Cgh.2014.05.007  0.656
2014 Onyiah JC, Sheikh SZ, Maharshak N, Otterbein LE, Plevy SE. Heme oxygenase-1 and carbon monoxide regulate intestinal homeostasis and mucosal immune responses to the enteric microbiota. Gut Microbes. 5: 220-4. PMID 24637794 DOI: 10.4161/Gmic.27290  0.705
2014 Steinbach EC, Kobayashi T, Russo SM, Sheikh SZ, Gipson GR, Kennedy ST, Uno JK, Mishima Y, Borst LB, Liu B, Herfarth H, Ting JP, Sartor RB, Plevy SE. Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis. Journal of Immunology (Baltimore, Md. : 1950). 192: 3958-68. PMID 24634494 DOI: 10.4049/Jimmunol.1301533  0.815
2014 Kobayashi T, Steinbach EC, Russo SM, Matsuoka K, Nochi T, Maharshak N, Borst LB, Hostager B, Garcia-Martinez JV, Rothman PB, Kashiwada M, Sheikh SZ, Murray PJ, Plevy SE. NFIL3-deficient mice develop microbiota-dependent, IL-12/23-driven spontaneous colitis. Journal of Immunology (Baltimore, Md. : 1950). 192: 1918-27. PMID 24442434 DOI: 10.4049/Jimmunol.1301819  0.815
2014 Tilstra JS, Gaddy DF, Zhao J, Davé SH, Niedernhofer LJ, Plevy SE, Robbins PD. Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death. Scientific Reports. 4: 3631. PMID 24406986 DOI: 10.1038/Srep03631  0.357
2014 Steinbach EC, Plevy SE. The role of macrophages and dendritic cells in the initiation of inflammation in IBD. Inflammatory Bowel Diseases. 20: 166-75. PMID 23974993 DOI: 10.1097/Mib.0B013E3182A69Dca  0.775
2014 Faubion WA, Fletcher JG, OʼByrne S, Feagan BG, de Villiers WJ, Salzberg B, Plevy S, Proctor DD, Valentine JF, Higgins PD, Harris JM, Diehl L, Wright L, Wei Tew G, Luca D, et al. Erratum: EMerging BiomARKers in Inflammatory Bowel Disease (EMBARK) Study Identifies Fecal Calprotectin, Serum MMP9, and Serum IL-22 as a Novel Combination of Biomarkers for Crohnʼs Disease Activity: Role of Cross-Sectional Imaging American Journal of Gastroenterology. 109: 780. DOI: 10.1038/Ajg.2014.69  0.371
2014 Sheikh SZ, Plevy SE. Gastrointestinal immunology and ecology Gastrointestinal Anatomy and Physiology: the Essentials. 46-57. DOI: 10.1002/9781118833001.ch4  0.631
2013 Faubion WA, Fletcher JG, O'Byrne S, Feagan BG, de Villiers WJ, Salzberg B, Plevy S, Proctor DD, Valentine JF, Higgins PD, Harris JM, Diehl L, Wright L, Tew GW, Luca D, et al. EMerging BiomARKers in Inflammatory Bowel Disease (EMBARK) study identifies fecal calprotectin, serum MMP9, and serum IL-22 as a novel combination of biomarkers for Crohn's disease activity: role of cross-sectional imaging. The American Journal of Gastroenterology. 108: 1891-900. PMID 24126633 DOI: 10.1038/Ajg.2013.354  0.384
2013 Maseda D, Candando KM, Smith SH, Kalampokis I, Weaver CT, Plevy SE, Poe JC, Tedder TF. Peritoneal cavity regulatory B cells (B10 cells) modulate IFN-γ+CD4+ T cell numbers during colitis development in mice. Journal of Immunology (Baltimore, Md. : 1950). 191: 2780-95. PMID 23918988 DOI: 10.4049/Jimmunol.1300649  0.38
2013 Maharshak N, Packey CD, Ellermann M, Manick S, Siddle JP, Huh EY, Plevy S, Sartor RB, Carroll IM. Altered enteric microbiota ecology in interleukin 10-deficient mice during development and progression of intestinal inflammation. Gut Microbes. 4: 316-24. PMID 23822920 DOI: 10.4161/Gmic.25486  0.493
2013 Plevy S, Silverberg MS, Lockton S, Stockfisch T, Croner L, Stachelski J, Brown M, Triggs C, Chuang E, Princen F, Singh S. Combined serological, genetic, and inflammatory markers differentiate non-IBD, Crohn's disease, and ulcerative colitis patients. Inflammatory Bowel Diseases. 19: 1139-48. PMID 23518807 DOI: 10.1097/Mib.0B013E318280B19E  0.383
2013 Lennon EM, Maharshak N, Elloumi H, Borst L, Plevy SE, Moeser AJ. Early life stress triggers persistent colonic barrier dysfunction and exacerbates colitis in adult IL-10-/- mice. Inflammatory Bowel Diseases. 19: 712-9. PMID 23446335 DOI: 10.1097/Mib.0B013E3182802A4E  0.417
2013 Sandborn WJ, Colombel JF, D'Haens G, Plevy SE, Panés J, Robinson AM, Pollack PF, Zhou Q, Castillo M, Thakkar RB. Association of baseline C-reactive protein and prior anti-tumor necrosis factor therapy with need for weekly dosing during maintenance therapy with adalimumab in patients with moderate to severe Crohn's disease. Current Medical Research and Opinion. 29: 483-93. PMID 23438483 DOI: 10.1185/03007995.2013.779575  0.315
2013 Dotan I, Plevy SE. NOD2 and pouch complications in UC patients: Old-world clinical dogmas give way to biological definitions Gut. 62: 1390-1391. PMID 23292664 DOI: 10.1136/Gutjnl-2012-303188  0.385
2013 Shinzaki S, Kuroki E, Iijima H, Tatsunaka N, Ishii M, Fujii H, Kamada Y, Kobayashi T, Shibukawa N, Inoue T, Tsujii M, Takeishi S, Mizushima T, Ogata A, Naka T, ... Plevy SE, et al. Lectin-based immunoassay for aberrant IgG glycosylation as the biomarker for Crohn's disease. Inflammatory Bowel Diseases. 19: 321-31. PMID 23287897 DOI: 10.1097/Mib.0B013E318280Eade  0.359
2013 Onyiah JC, Sheikh SZ, Maharshak N, Steinbach EC, Russo SM, Kobayashi T, Mackey LC, Hansen JJ, Moeser AJ, Rawls JF, Borst LB, Otterbein LE, Plevy SE. Carbon monoxide and heme oxygenase-1 prevent intestinal inflammation in mice by promoting bacterial clearance. Gastroenterology. 144: 789-98. PMID 23266559 DOI: 10.1053/J.Gastro.2012.12.025  0.785
2013 Hughes J, Herfarth H, Isaacs K, Plevy S, Sartor BR, Sheikh S, Hansen J, Long M. Infliximab Retreatment in Inflammatory Bowel Disease: A Single-center Experience American Journal of Gastroenterology. 108: S543. DOI: 10.14309/00000434-201310001-01801  0.666
2013 Maharshak N, Ellermann M, Gharaibeh R, Sha W, Perez-Chanona E, Whitehead K, Jobin C, Fodor A, Plevy S, Sartor R. P689 Iron supplemented diet protects against chronic immune mediated colitis in mice Journal of Crohn's and Colitis. 7: S287. DOI: 10.1016/S1873-9946(13)60710-2  0.334
2013 Plevy SE, Lockton S, Princen F, Singh S. 1029 Serological and Inflammatory IBD Marker Prevalence As Function of Age in a Large Cohort of Patients Presenting IBD-Like Gastrointestinal Symptoms Gastroenterology. 144: S-192-S-193. DOI: 10.1016/S0016-5085(13)60676-9  0.325
2013 Steinbach EC, Kobayashi T, Mishima Y, Liu B, Sartor RB, Ting JP, Plevy SE. 738 The Phosphoinositide 3-Kinase Subunit P1105 Regulates TH1/TH17 Skewing in Murine and Human IBD Gastroenterology. 144: S-133. DOI: 10.1016/S0016-5085(13)60478-3  0.73
2013 Ellermann M, Maharshak N, Gharaibeh R, Sha W, Perez-Chanona E, Whitehead KJ, Jobin C, Fodor A, Plevy SE, Sartor RB. 317 Iron Supplemented Diet Protects Against Chronic Immune Mediated Colitis in IL-10 Deficient Mice Gastroenterology. 144: S-66. DOI: 10.1016/S0016-5085(13)60241-3  0.392
2012 Holl EK, Roney KE, Allen IC, Steinbach E, Arthur JC, Buntzman A, Plevy S, Frelinger J, Ting JP. Plexin-B2 and Plexin-D1 in dendritic cells: expression and IL-12/IL-23p40 production. Plos One. 7: e43333. PMID 22916243 DOI: 10.1371/Journal.Pone.0043333  0.754
2012 Kobayashi T, Matsuoka K, Sheikh SZ, Russo SM, Mishima Y, Collins C, deZoeten EF, Karp CL, Ting JP, Sartor RB, Plevy SE. IL-10 regulates Il12b expression via histone deacetylation: implications for intestinal macrophage homeostasis. Journal of Immunology (Baltimore, Md. : 1950). 189: 1792-9. PMID 22786766 DOI: 10.4049/Jimmunol.1200042  0.725
2012 Gowdy KM, Cardona DM, Nugent JL, Giamberardino C, Thomas JM, Mukherjee S, Mukherjee S, Martinu T, Foster WM, Plevy SE, Pastva AM, Wright JR, Palmer SM. Novel role for surfactant protein A in gastrointestinal graft-versus-host disease. Journal of Immunology (Baltimore, Md. : 1950). 188: 4897-905. PMID 22508928 DOI: 10.4049/Jimmunol.1103558  0.363
2012 Elloumi HZ, Maharshak N, Rao KN, Kobayashi T, Ryu HS, Mühlbauer M, Li F, Jobin C, Plevy SE. A cell permeable peptide inhibitor of NFAT inhibits macrophage cytokine expression and ameliorates experimental colitis. Plos One. 7: e34172. PMID 22479554 DOI: 10.1371/Journal.Pone.0034172  0.477
2012 Serada S, Fujimoto M, Terabe F, Iijima H, Shinzaki S, Matsuzaki S, Ohkawara T, Nezu R, Nakajima S, Kobayashi T, Plevy SE, Takehara T, Naka T. Serum leucine-rich alpha-2 glycoprotein is a disease activity biomarker in ulcerative colitis. Inflammatory Bowel Diseases. 18: 2169-79. PMID 22374925 DOI: 10.1002/Ibd.22936  0.305
2012 Packey C, Maharshak N, Manick S, Hudson P, Ellerman M, Plevy S, Sartor R, Carroll I. Components of Enteric Dysbiosis Are Present at the Onset of Immune-mediated, Spontaneous Colitis Inflammatory Bowel Diseases. 18: S91. DOI: 10.1097/00054725-201212001-00222  0.335
2012 Mishima Y, Liu B, Holt LC, Steinbach EC, Plevy SE, Sartor RB. Tu1958 B Cells Contribute to Mucosal Homeostasis and Prevention of Colitis Through IL-10 Production Mediated by PI3K/AKT/GSK3- Signaling Gastroenterology. 142: S-886-S-887. DOI: 10.1016/S0016-5085(12)63445-3  0.765
2012 Mishima Y, Liu B, Kobayashi T, Plevy SE, Nochi T, Karp C, Garcia JV, Sartor RB. Mo1747 Intestinal IL-10-Producing B Cells Induced by Commensal Bacteria May Contribute to Maintenance of Mucosal Homeostasis Gastroenterology. 142: S-676. DOI: 10.1016/S0016-5085(12)62601-8  0.472
2012 Faubion WA, Fletcher JG, de Villiers WJ, Salzberg B, Plevy SE, Proctor DD, Valentine JF, Feagan BG, Higgins PD, Harris JM, Luca D, O'Byrne S, Keir ME. Mo1680 Assessing Crohn's Disease Inflammatory Biomarker Diagnostic Accuracy Using Ileocolonoscopy or a Combined Ileocolonoscopy-CTE Score in the Embark Study Gastroenterology. 142: S-658. DOI: 10.1016/S0016-5085(12)62535-9  0.325
2012 Steinbach EC, Maharshak N, Uno JK, Kobayashi T, Mishima Y, Liu B, Sartor RB, Plevy SE. 997 Spontaneous Colitis in PI3K P110Ô Knock-in (KI) Mice is Dependent on the Enteric Microbiota and is Mediated by Defects in Macrophage IL-10 Production Gastroenterology. 142: S-176. DOI: 10.1016/S0016-5085(12)60662-3  0.785
2012 Kobayashi T, Russo S, Matsuoka K, Nochi T, Borst LB, Garcia JV, Rothman PB, Kashiwada M, Plevy SE. 867 NFIL3 Deficient Mice Develop Severe Innate Immune Mediated Spontaneous Colitis Gastroenterology. 142: S-149. DOI: 10.1016/S0016-5085(12)60563-0  0.374
2012 Onyiah JC, Sheikh SZ, Maharshak N, Russo S, Steinbach EC, Kobayashi T, Mackey LC, Moeser AJ, Rawls JF, Otterbein LE, Plevy SE. 514 Heme Oxygenase-1 Maintains Intestinal Homeostasis Through Augmented Enteric Bacterial Clearance Gastroenterology. 142: S-107. DOI: 10.1016/S0016-5085(12)60404-1  0.77
2012 Plevy SE, Stockfisch TP, Lockton S, Croner LJ, Singh S, Princen F. 166 Combined Serologic, Genetic, and Inflammatory Markers Can Accurately Differentiate Non-IBD, Crohn's Disease, and Ulcerative Colitis Patients Gastroenterology. 142: S-41. DOI: 10.1016/S0016-5085(12)60155-3  0.351
2011 Maharshak N, Plevy SE. A Crohn's disease patient who does not respond to infliximab: what is next? Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 9: 1033-8. PMID 21699811 DOI: 10.1016/J.Cgh.2011.05.027  0.318
2011 Plevy SE, Targan SR. Future therapeutic approaches for inflammatory bowel diseases. Gastroenterology. 140: 1838-46. PMID 21530750 DOI: 10.1053/J.Gastro.2011.02.014  0.313
2011 Sheikh SZ, Hegazi RA, Kobayashi T, Onyiah JC, Russo SM, Matsuoka K, Sepulveda AR, Li F, Otterbein LE, Plevy SE. An anti-inflammatory role for carbon monoxide and heme oxygenase-1 in chronic Th2-mediated murine colitis. Journal of Immunology (Baltimore, Md. : 1950). 186: 5506-13. PMID 21444764 DOI: 10.4049/Jimmunol.1002433  0.736
2011 Kobayashi T, Matsuoka K, Sheikh SZ, Elloumi HZ, Kamada N, Hisamatsu T, Hansen JJ, Doty KR, Pope SD, Smale ST, Hibi T, Rothman PB, Kashiwada M, Plevy SE. NFIL3 is a regulator of IL-12 p40 in macrophages and mucosal immunity. Journal of Immunology (Baltimore, Md. : 1950). 186: 4649-55. PMID 21383239 DOI: 10.4049/Jimmunol.1003888  0.741
2011 Sheikh SZ, Kobayashi T, Matsuoka K, Onyiah JC, Plevy SE. Characterization of an interferon-stimulated response element (ISRE) in the Il23a promoter. The Journal of Biological Chemistry. 286: 1174-80. PMID 21097874 DOI: 10.1074/Jbc.M110.147884  0.724
2011 D'Haens GR, Panaccione R, Higgins PDR, Vermeire S, Gassull M, Chowers Y, Hanauer SB, Herfarth H, Hommes DW, Kamm M, Löfberg R, Quary A, Sands B, Sood A, Watermayer G, ... ... Plevy S, et al. The London position statement of the World Congress of gastroenterology on biological therapy for IBD with the European Crohn's and Colitis Organization: When to start, when to stop, which drug to choose, and how to predict response American Journal of Gastroenterology. 106: 199-212. PMID 21045814 DOI: 10.1038/Ajg.2010.392  0.303
2011 Shailubhai K, Nefsky B, Masih S, Foss J, Comiskey S, Jacob G, Plevy S. Guanylate Cyclase C Agonists, a New Class of Drug Candidates for Treatment of Inflammatory Bowel Disease American Journal of Gastroenterology. 106: S455. DOI: 10.14309/00000434-201110002-01208  0.309
2011 Kobayashi T, Matsuoka K, Sheikh S, de Zoeten E, Plevy S. Epigenetic regulation of IL-12 p40 by IL-10 in intestinal immunity Inflammatory Bowel Diseases. 17: S11. DOI: 10.1097/00054725-201112002-00032  0.7
2011 Hsu E, Ruffner M, Luu Y, Gao J, Fleet C, Jacobson K, Mumper R, Plevy S, Cheung A. Successful treatment of experimental colitis by a nanoparticle gene delivery system that localizes expression of interleukin-10 (IL-10) to the colon. Inflammatory Bowel Diseases. 17: S3-S3. DOI: 10.1093/Ibd/17.Supplement1.S3  0.342
2011 Sheikh SZ, Maharshak N, Onyiah J, Rawls J, Plevy S. Heme oxygenase-1 expression and function is protective against innate immune responses to the enteric microbiota Inflammatory Bowel Diseases. 17: S66. DOI: 10.1016/S0016-5085(09)60678-8  0.649
2011 Sheikh SZ, Uno J, Matsuoka K, Plevy SE. Reply to L. Xue and Q. Ouyang, "Diagnostic criteria of inflammatory bowel disease", Clinical Immunology. 139: 104. DOI: 10.1016/J.Clim.2011.01.005  0.641
2010 Sheikh SZ, Plevy SE. The role of the macrophage in sentinel responses in intestinal immunity. Current Opinion in Gastroenterology. 26: 578-82. PMID 20717022 DOI: 10.1097/Mog.0B013E32833D4B71  0.684
2010 Uno JK, Rao KN, Matsuoka K, Sheikh SZ, Kobayashi T, Li F, Steinbach EC, Sepulveda AR, Vanhaesebroeck B, Sartor RB, Plevy SE. Altered macrophage function contributes to colitis in mice defective in the phosphoinositide-3 kinase subunit p110δ. Gastroenterology. 139: 1642-53, 1653.e1-6. PMID 20637203 DOI: 10.1053/J.Gastro.2010.07.008  0.797
2010 Sheikh SZ, Matsuoka K, Kobayashi T, Li F, Rubinas T, Plevy SE. Cutting edge: IFN-gamma is a negative regulator of IL-23 in murine macrophages and experimental colitis. Journal of Immunology (Baltimore, Md. : 1950). 184: 4069-73. PMID 20228197 DOI: 10.4049/Jimmunol.0903600  0.723
2010 Kobayashi T, Matsuoka K, Sheikh SZ, Elloumi HZ, Plevy SE. S1756 The Bzip Protein E4bp4 Mediates IL-10 Regulation of Intestinal Macrophage Tolerance to the Enteric Microbiota Gastroenterology. 138: S-267-S-268. DOI: 10.1016/S0016-5085(10)61226-7  0.715
2010 Uno JK, Matsuoka K, Sheikh SZ, Li F, Steinbach EC, Russo S, Sartor RB, Plevy SE. 756 Functional Deficits in IL-10 and Phosphatidyl Inositol-3 Kinase (PI3K) Contribute to the Development of Severe Colitis Gastroenterology. 138: S-104. DOI: 10.1016/S0016-5085(10)60477-5  0.783
2010 Steinbach E, Uno J, Russo S, Plevy S. Defective Bactericidal Activity in PI3K p110δ Mutant Macrophages Contributes to the Development of Colitis Clinical Immunology. 135: S36-S37. DOI: 10.1016/J.Clim.2010.03.113  0.732
2009 Davé SH, Tilstra JS, Matsuoka K, Li F, DeMarco RA, Beer-Stolz D, Sepulveda AR, Fink MP, Lotze MT, Plevy SE. Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis. Journal of Leukocyte Biology. 86: 633-43. PMID 19454652 DOI: 10.1189/Jlb.1008662  0.497
2009 Han X, Uchida K, Jurickova I, Koch D, Willson T, Samson C, Bonkowski E, Trauernicht A, Kim MO, Tomer G, Dubinsky M, Plevy S, Kugathsan S, Trapnell BC, Denson LA. Granulocyte-macrophage colony-stimulating factor autoantibodies in murine ileitis and progressive ileal Crohn's disease. Gastroenterology. 136: 1261-71, e1-3. PMID 19230854 DOI: 10.1053/J.Gastro.2008.12.046  0.36
2009 Regueiro M, Schraut W, Baidoo L, Kip KE, Sepulveda AR, Pesci M, Harrison J, Plevy SE. Infliximab prevents Crohn's disease recurrence after ileal resection. Gastroenterology. 136: 441-50.e1; quiz 716. PMID 19109962 DOI: 10.1053/J.Gastro.2008.10.051  0.318
2009 Regueiro M, Schraut WH, Kip K, Baidoo L, Plevy SE, Rodemann JF, Sepulveda AR, Pesci M, Harrison J, Watson AR, Binion DG. W1152 Silent Crohn's Disease (CD): Poor Correlation Between Crohn's Disease Activity Index (CDAI) and Endoscopic Activity Scores One Year After Intestinal Resection and Ileocolonic Anastomosis Gastroenterology. 136: A-665. DOI: 10.1016/S0016-5085(09)63066-3  0.326
2009 Matsuoka K, Sheikh SZ, Li F, Uno JK, Plevy SE. S1719 Macrophage Tolerance to the Enteric Microbiota Is Mediated By IL-10 At the Chromatin Level Gastroenterology. 136: A-256. DOI: 10.1016/S0016-5085(09)61165-3  0.699
2009 Uno JK, Rao KN, Matsuoka K, Sheikh SZ, Li F, Plevy SE. 1092 Altered Macrophage Function Contributes to Colitis Development in PI3K P110δ Mutant Mice Gastroenterology. 136: A-168. DOI: 10.1016/S0016-5085(09)60759-9  0.664
2009 Sheikh SZ, Matsuoka K, Uno JK, Li F, Plevy SE. 980 Heme Oxygenase-1 Expression and Function Is Protective Against Innate Immune Responses to the Enteric Microbiota Gastroenterology. 136: A-150-A-151. DOI: 10.1016/S0016-5085(09)60678-8  0.62
2009 Sheikh SZ, Matsuoka K, Uno JK, Li F, Plevy SE. 367 Molecular Regulation of Il23a Gene Expression in Murine Macrophages and Experimental Colitis Gastroenterology. 136: A-60. DOI: 10.1016/S0016-5085(09)60270-5  0.721
2008 Sheikh S, Uno J, Matsuoka K, Plevy S. Abnormal mucosal immune response to altered bacterial flora following restorative proctocolectomy in patients with ulcerative colitis: serologic measures, immunogenetics, and clinical correlations. Clinical Immunology (Orlando, Fla.). 127: 270-9. PMID 18499066 DOI: 10.1016/J.Clim.2008.03.511  0.699
2008 Levy LC, Plevy SE. Farm animals and inflammatory bowel disease: old MacDonald had poor hygiene. Gastroenterology. 134: 886-7; discussion 88. PMID 18325401 DOI: 10.1053/J.Gastro.2008.01.047  0.37
2008 Abreu MT, Plevy S, Sands BE, Weinstein R. Selective leukocyte apheresis for the treatment of inflammatory bowel disease. Journal of Clinical Gastroenterology. 41: 874-88. PMID 18090155 DOI: 10.1097/Mcg.0B013E3180479435  0.39
2008 Matsuoka K, Sheikh S, Li F, Uno J, Plevy S. NOD2 activates NF-kB p65 serine phosphorylation through a phosphatidylinositol 3-kinase dependant pathway: O-009. Inflammatory Bowel Diseases. 14. DOI: 10.1097/00054725-200801001-00009  0.611
2008 Matsuoka K, Sheikh S, Li F, Plevy S. Sa.123. NOD2 Activates NF-κB p65 Serine Phosphorylation Through a Phosphatidylinositol 3-kinase Dependent Pathway Clinical Immunology. 127: S121. DOI: 10.1016/J.Clim.2008.03.344  0.617
2008 Uno J, Rao K, Matsuoka K, Li F, Sartor R, Plevy S. Sa.120. Altered Innate Immunity Contributes to the Development of Colitis in PI3K p110δ Mutant Mice Clinical Immunology. 127: S119-S120. DOI: 10.1016/J.Clim.2008.03.341  0.372
2008 Sheikh S, Matsuoka K, Li F, Plevy S. Sa.118. Molecular Regulation of IL-23 p19 Gene Expression in Macrophages and Murine Inflammatory Bowel Disease Clinical Immunology. 127: S119. DOI: 10.1016/J.Clim.2008.03.339  0.717
2007 Davé SH, Tilstra JS, Matsuoka K, Li F, Karrasch T, Uno JK, Sepulveda AR, Jobin C, Baldwin AS, Robbins PD, Plevy SE. Amelioration of chronic murine colitis by peptide-mediated transduction of the IkappaB kinase inhibitor NEMO binding domain peptide. Journal of Immunology (Baltimore, Md. : 1950). 179: 7852-9. PMID 18025231 DOI: 10.4049/Jimmunol.179.11.7852  0.362
2007 Meier C, Plevy S. Therapy insight: how the gut talks to the joints--inflammatory bowel disease and the spondyloarthropathies. Nature Clinical Practice. Rheumatology. 3: 667-74. PMID 17968338 DOI: 10.1038/Ncprheum0625  0.429
2007 Beatty PL, Plevy SE, Sepulveda AR, Finn OJ. Cutting edge: transgenic expression of human MUC1 in IL-10-/- mice accelerates inflammatory bowel disease and progression to colon cancer. Journal of Immunology (Baltimore, Md. : 1950). 179: 735-9. PMID 17617560 DOI: 10.4049/Jimmunol.179.2.735  0.463
2007 Bogunovic M, Davé SH, Tilstra JS, Chang DT, Harpaz N, Xiong H, Mayer LF, Plevy SE. Enteroendocrine cells express functional Toll-like receptors. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G1770-83. PMID 17395901 DOI: 10.1152/Ajpgi.00249.2006  0.384
2007 Barrie A, Plevy S. Treatment of immune-mediated extraintestinal manifestations of inflammatory bowel disease with infliximab. Gastroenterology Clinics of North America. 35: 883-93. PMID 17129819 DOI: 10.1016/J.Gtc.2006.09.001  0.353
2007 Matsuoka K, Dave S, Tilstra J, Li F, DeMarco R, Fink M, Lotze M, Plevy S. PAMPs and DAMPs in IBD Inflammatory Bowel Diseases. 13: 643. DOI: 10.1097/00054725-200705001-00003  0.315
2006 Sheikh S, Plevy S. Medical Management of Surgical Inflammatory Bowel Disease? Current Concepts and Future Possibilities Seminars in Colon and Rectal Surgery. 17: 50-54. DOI: 10.1053/J.Scrs.2006.06.007  0.655
2005 Hegazi RA, Rao KN, Mayle A, Sepulveda AR, Otterbein LE, Plevy SE. Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1-dependent pathway. The Journal of Experimental Medicine. 202: 1703-13. PMID 16365149 DOI: 10.1084/Jem.20051047  0.482
2005 Regueiro M, Kip KE, Cheung O, Hegazi RA, Plevy S. Cigarette smoking and age at diagnosis of inflammatory bowel disease. Inflammatory Bowel Diseases. 11: 42-7. PMID 15674112 DOI: 10.1097/00054725-200501000-00006  0.303
2005 Plevy S. A STAT need for human immunologic studies to understand inflammatory bowel disease. The American Journal of Gastroenterology. 100: 73-4. PMID 15654783 DOI: 10.1111/J.1572-0241.2005.41382.X  0.39
2005 Barrie AM, Plevy SE. The interleukin-12 family of cytokines: Therapeutic targets for inflammatory disease mediation Clinical and Applied Immunology Reviews. 5: 225-240. DOI: 10.1016/J.Cair.2005.06.003  0.452
2004 Papachristou GI, Wu T, Marsh W, Plevy SE. Inflammatory pseudotumor of the liver associated with Crohn's disease. Journal of Clinical Gastroenterology. 38: 818-22. PMID 15365413 DOI: 10.1097/00004836-200410000-00020  0.36
2004 Papachristou GI, Plevy S. Novel biologics in inflammatory bowel disease. Gastroenterology Clinics of North America. 33: 251-69, ix. PMID 15177537 DOI: 10.1016/J.Gtc.2004.02.007  0.395
2004 Plevy S. Do serological markers and cytokines determine the indeterminate? Journal of Clinical Gastroenterology. 38: S51-6. PMID 15115933 DOI: 10.1097/01.Mcg.0000124026.92823.Fc  0.326
2004 Zhou H, Xiong H, Li H, Plevy SE, Walden PD, Sassaroli M, Prestwich GD, Unkeless JC. Microtubule-associated serine/threonine kinase-205 kDa and Fc gamma receptor control IL-12 p40 synthesis and NF-kappa B activation. Journal of Immunology (Baltimore, Md. : 1950). 172: 2559-68. PMID 14764729 DOI: 10.4049/Jimmunol.172.4.2559  0.423
2004 Xiong H, Zhu C, Li F, Hegazi R, He K, Babyatsky M, Bauer AJ, Plevy SE. Inhibition of interleukin-12 p40 transcription and NF-kappaB activation by nitric oxide in murine macrophages and dendritic cells. The Journal of Biological Chemistry. 279: 10776-83. PMID 14679201 DOI: 10.1074/Jbc.M313416200  0.447
2003 Regueiro M, Valentine J, Plevy S, Fleisher MR, Lichtenstein GR. Infliximab for treatment of pyoderma gangrenosum associated with inflammatory bowel disease. The American Journal of Gastroenterology. 98: 1821-6. PMID 12907338 DOI: 10.1111/J.1572-0241.2003.07581.X  0.322
2003 Zhu C, Rao K, Xiong H, Gagnidze K, Li F, Horvath C, Plevy S. Activation of the murine interleukin-12 p40 promoter by functional interactions between NFAT and ICSBP. The Journal of Biological Chemistry. 278: 39372-82. PMID 12876285 DOI: 10.1074/Jbc.M306441200  0.428
2003 Plevy S, Mayer L. Meeting summary: Signal transduction pathways in immune and inflammatory cells. November 30-December 3, 2000, Amelia Island, Florida, U.S.A. Inflammatory Bowel Diseases. 9: 28-33. PMID 12656135 DOI: 10.1097/00054725-200301000-00005  0.408
2003 Xiong H, Zhu C, Li H, Chen F, Mayer L, Ozato K, Unkeless JC, Plevy SE. Complex formation of the interferon (IFN) consensus sequence-binding protein with IRF-1 is essential for murine macrophage IFN-gamma-induced iNOS gene expression. The Journal of Biological Chemistry. 278: 2271-7. PMID 12429737 DOI: 10.1074/Jbc.M209583200  0.312
2003 Hegazi R, Salem R, Otterbein L, Plevy SE. Immunosuppressive effects of carbon monoxide in IL-10 deficient macrophages Gastroenterology. 124: A101. DOI: 10.1016/S0016-5085(03)80496-1  0.389
2003 Plevy SE, Salzberg BA, Regueiro M, Sandborn W, Hanauer SB, Targan SR, Mayer L, Walters IB. A humanized anti-CD3 monoclonal antibody, visilizumab, for treatment of severe steroid-refractory ulcerative colitis: Preliminary results of a phase I study Gastroenterology. 124: A7. DOI: 10.1016/S0016-5085(03)80033-1  0.307
2003 Regueiro M, Valentine J, Plevy S, Fleisher MR, Lichtenstein GR. Original contributionInfliximab for treatment of pyoderma gangrenosum associated with inflammatory bowel disease The American Journal of Gastroenterology. 98. DOI: 10.1016/S0002-9270(03)00430-1  0.379
2002 Plevy S. The immunology of inflammatory bowel disease. Gastroenterology Clinics of North America. 31: 77-92. PMID 12122745 DOI: 10.1016/S0889-8553(01)00006-1  0.363
2001 Cornillie F, Shealy D, D'Haens G, Geboes K, Van Assche G, Ceuppens J, Wagner C, Schaible T, Plevy SE, Targan SR, Rutgeerts P. Infliximab induces potent anti-inflammatory and local immunomodulatory activity but no systemic immune suppression in patients with Crohn's disease Alimentary Pharmacology and Therapeutics. 15: 463-473. PMID 11284774 DOI: 10.1046/J.1365-2036.2001.00956.X  0.407
2001 Zhu C, Gagnidze K, Gemberling JHM, Plevy SE. Characterization of an activation protein-1-binding site in the murine interleukin-12 p40 promoter: Demonstration of novel functional elements by a reductionist approach Journal of Biological Chemistry. 276: 18519-18528. PMID 11279072 DOI: 10.1074/Jbc.M100440200  0.38
2000 Brightbill HD, Plevy SE, Modlin RL, Smale ST. A prominent role for Sp1 during lipopolysaccharide-mediated induction of the IL-10 promoter in macrophages. Journal of Immunology (Baltimore, Md. : 1950). 164: 1940-51. PMID 10657644 DOI: 10.4049/Jimmunol.164.4.1940  0.409
2000 Bogunovic M, Reka S, Evans KN, Mayer LF, Sperber K, Plevy SE. Functional toll-like receptors (TLR) are expressed on intestinal epithelial cells (IEC) Gastroenterology. 118: A804. DOI: 10.1016/S0016-5085(00)85357-3  0.311
1999 Weinmann AS, Plevy SE, Smale ST. Rapid and selective remodeling of a positioned nucleosome during the induction of IL-12 p40 transcription. Immunity. 11: 665-75. PMID 10626889 DOI: 10.1016/S1074-7613(00)80141-7  0.331
1999 Brightbill HD, Libraty DH, Krutzik SR, Yang RB, Belisle JT, Bleharski JR, Maitland M, Norgard MV, Plevy SE, Smale ST, Brennan PJ, Bloom BR, Godowski PJ, Modlin RL. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science (New York, N.Y.). 285: 732-6. PMID 10426995 DOI: 10.1126/Science.285.5428.732  0.414
1999 Facklis K, Plevy SE, Vasiliauskas EA, Kam L, Taylor K, Targan SR, Fleshner PR. Crohn's disease-associated genetic marker is seen in medically unresponsive ulcerative colitis patients and may be associated with pouch- specific complications Diseases of the Colon and Rectum. 42: 601-606. PMID 10344681 DOI: 10.1007/Bf02234133  0.302
1998 Taylor K, Li Z, Barry M, Fischel-Ghodsian N, Plevy S, Rotter J, Targan S, Yang H. Tumor necrosis factor microsatellite haplotype A11B4C1D3E3 is associated with anti-Saccharomyces cerevisiae antibody (ASCA) across clinical forms of inflammatory bowel disease Gastroenterology. 114: A1098. DOI: 10.1016/S0016-5085(98)84463-6  0.324
1998 Prehn J, Plevy S, Landers C, Targan S. The role of TNF-α in Crohn's disease: INF-α mediated augmentation of LPMC INF-γ production is IL-12 and IL-18 independent Gastroenterology. 114: A1064. DOI: 10.1016/S0016-5085(98)84327-8  0.392
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