Year |
Citation |
Score |
2019 |
Sun CW, Wu LC, Wankhede M, Wang D, Thoerner J, Woody L, Sorg BS, Townes TM, Terman DS. Exogenous sickle erythrocytes combined with vascular disruption trigger disseminated tumor vaso-occlusion and lung tumor regression. Jci Insight. 4. PMID 30944254 DOI: 10.1172/Jci.Insight.125535 |
0.427 |
|
2019 |
Sun CW, Yang J, Kleschyov A, Zhuge Z, Carlstrom M, Pernow J, Wajih N, Isbell TS, Oh JY, Cabrales P, Tsai A, Townes T, Kim-Shapiro DB, Patel RP, Lundberg JO. Hemoglobin β93 Cysteine is Not Required for Export of Nitric Oxide Bioactivity From the Red Blood Cell. Circulation. PMID 30905171 DOI: 10.1161/Circulationaha.118.039284 |
0.331 |
|
2018 |
Devadasan D, Sun CW, Westin ER, Wu LC, Pawlik KM, Townes TM, Goldman FD. Bmt Following Non-Myeloablative Treosulfan Conditioning is Curative in a Murine Model of Sickle Cell Disease. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 29684562 DOI: 10.1016/J.Bbmt.2018.04.011 |
0.497 |
|
2017 |
Sun CW, Wu LC, Knopick PL, Bradley DS, Townes T, Terman DS. Sickle Cells Produce Functional Immune Modulators and Cytotoxics. American Journal of Hematology. PMID 28646491 DOI: 10.1002/Ajh.24836 |
0.57 |
|
2017 |
Giordano S, Zhao X, Chen YF, Litovsky SH, Hage FG, Townes TM, Sun CW, Wu LC, Oparil S, Xing D. Induced Pluripotent Stem Cell-Derived Endothelial Cells Overexpressing Interleukin-8 Receptors A/B and/or C-C Chemokine Receptors 2/5 Inhibit Vascular Injury Response. Stem Cells Translational Medicine. PMID 28233474 DOI: 10.1002/Sctm.16-0316 |
0.467 |
|
2016 |
Li C, Ding L, Sun CW, Wu LC, Zhou D, Pawlik KM, Khodadadi-Jamayran A, Westin E, Goldman FD, Townes TM. Novel HDAd/EBV Reprogramming Vector and Highly Efficient Ad/CRISPR-Cas Sickle Cell Disease Gene Correction. Scientific Reports. 6: 30422. PMID 27460639 DOI: 10.1038/Srep30422 |
0.524 |
|
2016 |
Sun CW, Willmon C, Wu LC, Knopick P, Thoerner J, Vile R, Townes TM, Terman DS. Sickle Cells Abolish Melanoma Tumorigenesis in Hemoglobin SS Knockin Mice and Augment the Tumoricidal Effect of Oncolytic Virus In Vivo. Frontiers in Oncology. 6: 166. PMID 27458571 DOI: 10.3389/Fonc.2016.00166 |
0.498 |
|
2016 |
Kang L, Yao C, Khodadadi-Jamayran A, Xu W, Zhang R, Banerjee NS, Chang CW, Chow LT, Townes T, Hu K. The universal 3D3 antibody of human PODXL is pluripotent cytotoxic, and identifies a residual population after extended differentiation of pluripotent stem cells. Stem Cells and Development. PMID 26886504 DOI: 10.1089/Scd.2015.0321 |
0.381 |
|
2016 |
Chen Y, Giordano S, Xing D, Hage F, Townes T, Sun C, Wu L, Wallcott G, Brott B, Oparil S. PS 04-23 NOVEL TARGETED ENDOTHELIAL CELL THERAPY FOR VASCULAR INJURY IN RODENT AND PORCINE MODELS Journal of Hypertension. 34: e139. DOI: 10.1097/01.Hjh.0000500257.80486.2F |
0.5 |
|
2015 |
Gu Y, Jones AE, Yang W, Liu S, Dai Q, Liu Y, Swindle CS, Zhou D, Zhang Z, Ryan TM, Townes TM, Klug CA, Chen D, Wang H. The histone H2A deubiquitinase Usp16 regulates hematopoiesis and hematopoietic stem cell function. Proceedings of the National Academy of Sciences of the United States of America. PMID 26699484 DOI: 10.1073/Pnas.1517041113 |
0.322 |
|
2015 |
Zhang L, Tung NT, Su H, Wang R, Lu Y, Tang H, Aoyagi S, Guo A, Khodadadi-Jamayran A, Zhou D, Qian K, Hricik T, Côté J, Han X, Zhou W, ... ... Townes T, et al. Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing. Elife. 4. PMID 26575292 DOI: 10.7554/Elife.07938 |
0.345 |
|
2015 |
Chang CW, Lai YS, Westin E, Khodadadi-Jamayran A, Pawlik KM, Lamb LS, Goldman FD, Townes TM. Modeling Human Severe Combined Immunodeficiency and Correction by CRISPR/Cas9-Enhanced Gene Targeting. Cell Reports. 12: 1668-77. PMID 26321643 DOI: 10.1016/J.Celrep.2015.08.013 |
0.584 |
|
2015 |
Townes TM, Ding L, Chang C, Lai Y, Sun J, Pawlik K. Modified IPS Cells for Hemoglobinopathies Blood. 126: SCI-17-SCI-17. DOI: 10.1182/blood.V126.23.SCI-17.SCI-17 |
0.317 |
|
2015 |
Gu Y, Yang W, Jones A, Liu S, Dai Q, Swindle CS, Ryan T, Townes TM, Klug C, Wang H. Regulation of Hematopoietic Stem Cell Function By the Histone H2A Deubiquitinase Usp16 Blood. 126: 1177-1177. DOI: 10.1182/blood.V126.23.1177.1177 |
0.319 |
|
2014 |
Yang Z, Augustin J, Chang C, Hu J, Shah K, Chang CW, Townes T, Jiang H. The DPY30 subunit in SET1/MLL complexes regulates the proliferation and differentiation of hematopoietic progenitor cells. Blood. 124: 2025-33. PMID 25139354 DOI: 10.1182/Blood-2014-01-549220 |
0.426 |
|
2014 |
Chang CW, Lai YS, Lamb LS, Townes TM. Broad T-cell receptor repertoire in T-lymphocytes derived from human induced pluripotent stem cells. Plos One. 9: e97335. PMID 24828440 DOI: 10.1371/Journal.Pone.0097335 |
0.543 |
|
2014 |
Peralta R, Low A, Booten S, Zhou D, Kim A, Freier S, Guo S, Murray S, Townes TM, Hung G. Targeting KLF1 for the Treatment of Sickle Cell Disease Using Antisense Oligonucleotides Blood. 124: 4038-4038. DOI: 10.1182/Blood.V124.21.4038.4038 |
0.312 |
|
2013 |
Vitturi DA, Sun CW, Harper VM, Thrash-Williams B, Cantu-Medellin N, Chacko BK, Peng N, Dai Y, Wyss JM, Townes T, Patel RP. Antioxidant functions for the hemoglobin β93 cysteine residue in erythrocytes and in the vascular compartment in vivo. Free Radical Biology & Medicine. 55: 119-29. PMID 23159546 DOI: 10.1016/J.Freeradbiomed.2012.11.003 |
0.321 |
|
2013 |
Yang Z, Augustin J, Hu J, Chang C, Townes TM, Jiang H. Role Of Dpy30/MLL Complexes In Regulating Hematopoietic Progenitor Cell Maintenance and Differentiation Blood. 122: 2424-2424. DOI: 10.1182/blood.V122.21.2424.2424 |
0.314 |
|
2013 |
Peralta R, Low A, Kim A, Murray S, Guo S, Freier S, Townes TM, Hung G. Targeting BCL11A and KLF1 For The Treatment Of Sickle Cell Disease and β-Thalassemia In Vitro using Antisense Oligonucleotides Blood. 122: 1022-1022. DOI: 10.1182/BLOOD.V122.21.1022.1022 |
0.31 |
|
2012 |
Lai YS, Chang CW, Pawlik KM, Zhou D, Renfrow MB, Townes TM. SRY (sex determining region Y)-box2 (Sox2)/poly ADP-ribose polymerase 1 (Parp1) complexes regulate pluripotency. Proceedings of the National Academy of Sciences of the United States of America. 109: 3772-7. PMID 22362888 DOI: 10.1073/Pnas.1108595109 |
0.579 |
|
2011 |
Zhang Z, Jones A, Sun CW, Li C, Chang CW, Joo HY, Dai Q, Mysliwiec MR, Wu LC, Guo Y, Yang W, Liu K, Pawlik KM, Erdjument-Bromage H, Tempst P, ... ... Townes TM, et al. PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming. Stem Cells (Dayton, Ohio). 29: 229-40. PMID 21732481 DOI: 10.1002/Stem.578 |
0.569 |
|
2009 |
Chang CW, Lai YS, Pawlik KM, Liu K, Sun CW, Li C, Schoeb TR, Townes TM. Polycistronic lentiviral vector for "hit and run" reprogramming of adult skin fibroblasts to induced pluripotent stem cells. Stem Cells (Dayton, Ohio). 27: 1042-9. PMID 19415770 DOI: 10.1002/Stem.39 |
0.594 |
|
2008 |
Townes TM. Gene replacement therapy for sickle cell disease and other blood disorders. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 193-6. PMID 19074080 DOI: 10.1182/asheducation-2008.1.193 |
0.307 |
|
2008 |
Isbell TS, Sun CW, Wu LC, Teng X, Vitturi DA, Branch BG, Kevil CG, Peng N, Wyss JM, Ambalavanan N, Schwiebert L, Ren J, Pawlik KM, Renfrow MB, Patel RP, ... Townes TM, et al. SNO-hemoglobin is not essential for red blood cell-dependent hypoxic vasodilation. Nature Medicine. 14: 773-7. PMID 18516054 DOI: 10.1038/Nm1771 |
0.502 |
|
2007 |
Hanna J, Wernig M, Markoulaki S, Sun CW, Meissner A, Cassady JP, Beard C, Brambrink T, Wu LC, Townes TM, Jaenisch R. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science (New York, N.Y.). 318: 1920-3. PMID 18063756 DOI: 10.1126/Science.1152092 |
0.569 |
|
2006 |
Wu LC, Sun CW, Ryan TM, Pawlik KM, Ren J, Townes TM. Correction of sickle cell disease by homologous recombination in embryonic stem cells. Blood. 108: 1183-8. PMID 16638928 DOI: 10.1016/J.Bcmd.2006.10.134 |
0.565 |
|
2004 |
Yang X, Matsuda K, Bialek P, Jacquot S, Masuoka HC, Schinke T, Li L, Brancorsini S, Sassone-Corsi P, Townes TM, Hanauer A, Karsenty G. ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome. Cell. 117: 387-98. PMID 15109498 DOI: 10.1016/S0092-8674(04)00344-7 |
0.662 |
|
2004 |
Ryan TM, Sun C, Wu L, Ren J, Townes TM. Correction of β Thalassemia by Homologous Recombination in Embryonic Stem Cells. Blood. 104: 373-373. DOI: 10.1182/Blood.V104.11.373.373 |
0.546 |
|
2004 |
Reik A, Milner JD, Ryan T, Gregory PD, Townes T, Case CC. 901. Transactivation of fetal hemoglobin genes by engineered zinc-finger protein transcription factors for the treatment of sickle cell disease Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.807 |
0.379 |
|
2003 |
Heck S, Ermakova O, Iwasaki H, Akashi K, Sun CW, Ryan TM, Townes T, Graf T. Distinguishable live erythroid and myeloid cells in beta-globin ECFP x lysozyme EGFP mice. Blood. 101: 903-6. PMID 12393544 DOI: 10.1182/Blood-2002-06-1861 |
0.357 |
|
2002 |
Pandya K, Townes TM. Basic residues within the Kruppel zinc finger DNA binding domains are the critical nuclear localization determinants of EKLF/KLF-1. The Journal of Biological Chemistry. 277: 16304-12. PMID 11844803 DOI: 10.1074/Jbc.M200866200 |
0.697 |
|
2002 |
Masuoka HC, Townes TM. Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice. Blood. 99: 736-45. PMID 11806972 DOI: 10.1182/Blood.V99.3.736 |
0.699 |
|
2001 |
Pandya K, Donze D, Townes TM. Novel transactivation domain in erythroid Kruppel-like factor (EKLF). The Journal of Biological Chemistry. 276: 8239-43. PMID 11092887 DOI: 10.1074/Jbc.M008457200 |
0.711 |
|
2000 |
Chen W, Wu X, Levasseur DN, Liu H, Lai L, Kappes JC, Townes TM. Lentiviral vector transduction of hematopoietic stem cells that mediate long-term reconstitution of lethally irradiated mice Stem Cells. 18: 352-359. PMID 11007919 DOI: 10.1634/Stemcells.18-5-352 |
0.32 |
|
2000 |
Pandya KR, Townes TM. Multiple transacnvation domains of erythroid kruppel-like factor (eklf) Blood. 96. |
0.711 |
|
1997 |
Farmer SC, Sun CW, Winnier GE, Hogan BL, Townes TM. The bZIP transcription factor LCR-F1 is essential for mesoderm formation in mouse development. Genes & Development. 11: 786-98. PMID 9087432 DOI: 10.1101/gad.11.6.786 |
0.332 |
|
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