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Ronald M. Evans - Publications

Affiliations: 
Salk Institute for Biological Studies, La Jolla, CA, United States 
Area:
hormone, gene expression
Website:
http://www.salk.edu/faculty/faculty/details.php?id=21

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Year Citation  Score
2021 Iwamoto M, Masuya T, Hosose M, Tagawa K, Ishibashi T, Yoshihara E, Downes M, Evans RM, Matsushima A. Bisphenol A derivatives act as novel coactivator binding inhibitors for estrogen receptor β. The Journal of Biological Chemistry. 101173. PMID 34499926 DOI: 10.1016/j.jbc.2021.101173  1
2021 Wang L, Oh TG, Magida J, Estepa G, Obayomi SMB, Chong LW, Gatchalian J, Yu RT, Atkins AR, Hargreaves D, Downes M, Wei Z, Evans RM. Bromodomain containing 9 (BRD9) regulates macrophage inflammatory responses by potentiating glucocorticoid receptor activity. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34446564 DOI: 10.1073/pnas.2109517118  1
2021 Abu-Odeh M, Zhang Y, Reilly SM, Ebadat N, Keinan O, Valentine JM, Hafezi-Bakhtiari M, Ashayer H, Mamoun L, Zhou X, Zhang J, Yu RT, Dai Y, Liddle C, Downes M, ... Evans RM, et al. FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes. Cell Reports. 35: 109331. PMID 34192547 DOI: 10.1016/j.celrep.2021.109331  1
2021 Xu S, Chaudhary O, Rodríguez-Morales P, Sun X, Chen D, Zappasodi R, Xu Z, Pinto AFM, Williams A, Schulze I, Farsakoglu Y, Varanasi SK, Low JS, Tang W, Wang H, ... ... Evans RM, et al. Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8 T cells in tumors. Immunity. PMID 34102100 DOI: 10.1016/j.immuni.2021.05.003  1
2021 Liu S, Kim DI, Oh TG, Pao GM, Kim JH, Palmiter RD, Banghart MR, Lee KF, Evans RM, Han S. Neural basis of opioid-induced respiratory depression and its rescue. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34074761 DOI: 10.1073/pnas.2022134118  1
2021 Oh TG, Kim SM, Atkins AR, Yu RT, Downes M, Evans RM, Loomba R. Proton pump inhibitor use status does not modify the microbiome signature for cirrhosis. Cell Metabolism. 33: 457. PMID 33657386 DOI: 10.1016/j.cmet.2021.02.013  1
2021 Zhou R, Llorente C, Cao J, Zaramela LS, Zeng S, Gao B, Li SZ, Welch RD, Huang FQ, Qi LW, Pan C, Huang Y, Zhou P, Beussen I, Zhang Y, ... ... Evans RM, et al. Intestinal α1-2-fucosylation contributes to obesity and steatohepatitis in mice. Cellular and Molecular Gastroenterology and Hepatology. PMID 33631374 DOI: 10.1016/j.jcmgh.2021.02.009  1
2021 Yoshihara E, O'Connor C, Gasser E, Wei Z, Oh TG, Tseng TW, Wang D, Cayabyab F, Dai Y, Yu RT, Liddle C, Atkins AR, Downes M, Evans RM. Publisher Correction: Immune-evasive human islet-like organoids ameliorate diabetes. Nature. PMID 33469222 DOI: 10.1038/s41586-020-03109-3  1
2020 Noel P, Hussein S, Ng S, Antal CE, Lin W, Rodela E, Delgado P, Naveed S, Downes M, Lin Y, Evans RM, Von Hoff DD, Han H. Triptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibroblasts. Oncogenesis. 9: 100. PMID 33168807 DOI: 10.1038/s41389-020-00285-9  1
2020 Oh TG, Kim SM, Caussy C, Fu T, Guo J, Bassirian S, Singh S, Madamba EV, Bettencourt R, Richards L, Yu RT, Atkins AR, Huan T, Brenner DA, Sirlin CB, ... ... Evans RM, et al. A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis. Cell Metabolism. 32: 901. PMID 33147487 DOI: 10.1016/j.cmet.2020.10.015  1
2020 Evans RM, Lippman SM. Shining Light on the COVID-19 Pandemic: A Vitamin D Receptor Checkpoint in Defense of Unregulated Wound Healing. Cell Metabolism. PMID 32941797 DOI: 10.1016/j.cmet.2020.09.007  0.01
2020 Lenkiewicz E, Malasi S, Hogenson TL, Flores LF, Barham W, Phillips WJ, Roesler AS, Chambers KR, Rajbhandari N, Hayashi A, Grandgenett PM, Hollingsworth MA, Cridebring D, Xiong Y, Lee JH, et al. Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas. Cancer Research. PMID 32928922 DOI: 10.1158/0008-5472.Can-20-0078  0.08
2020 Yoshihara E, O'Connor C, Gasser E, Wei Z, Oh TG, Tseng TW, Wang D, Cayabyab F, Dai Y, Yu RT, Liddle C, Atkins AR, Downes M, Evans RM. Immune-evasive human islet-like organoids ameliorate diabetes. Nature. PMID 32814902 DOI: 10.1038/s41586-020-2631-z  1
2020 Reilly SM, Hung CW, Ahmadian M, Zhao P, Keinan O, Gomez AV, DeLuca JH, Dadpey B, Lu D, Zaid J, Poirier B, Peng X, Yu RT, Downes M, Liddle C, ... Evans RM, et al. Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3. Nature Metabolism. 2: 620-634. PMID 32694788 DOI: 10.1038/s42255-020-0217-6  1
2020 Oh TG, Kim SM, Caussy C, Fu T, Guo J, Bassirian S, Singh S, Madamba EV, Bettencourt R, Richards L, Raffatellu M, Dorrestein PC, Yu RT, Atkins AR, Huan T, ... ... Evans RM, et al. A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis. Cell Metabolism. PMID 32610095 DOI: 10.1016/J.Cmet.2020.06.005  1
2020 Paschoal VA, Walenta E, Talukdar S, Pessentheiner AR, Osborn O, Hah N, Chi TJ, Tye GL, Armando AM, Evans RM, Chi NW, Quehenberger O, Olefsky JM, Oh DY. Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity. Cell Metabolism. PMID 32413335 DOI: 10.1016/J.Cmet.2020.04.020  1
2020 Seidman JS, Troutman TD, Sakai M, Gola A, Spann NJ, Bennett H, Bruni CM, Ouyang Z, Li RZ, Sun X, Vu BT, Pasillas MP, Ego KM, Gosselin D, Link VM, ... ... Evans RM, et al. Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis. Immunity. PMID 32362324 DOI: 10.1016/J.Immuni.2020.04.001  1
2020 Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, ... ... Evans RM, et al. Global chemical effects of the microbiome include new bile-acid conjugations. Nature. PMID 32103176 DOI: 10.1038/S41586-020-2047-9  1
2020 Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, et al. A framework for advancing our understanding of cancer-associated fibroblasts. Nature Reviews. Cancer. PMID 31980749 DOI: 10.1038/S41568-019-0238-1  1
2020 McAdam J, Williams K, Tuggle C, Reams J, Peoples B, Cunningham G, Seay G, Wiggins D, Kelley C, Lavin K, Aban I, Tingle B, Downes M, Zhang J, Barragan C, ... ... Evans R, et al. PHITE: Precision High Intensity Training Through Epigenetics Medicine & Science in Sports & Exercise. 52: 906-906. DOI: 10.1249/01.Mss.0000685396.13917.0F  0.01
2020 Perez K, Cleary JM, Karasic TB, Raghavan S, Rahma OE, Nowak J, Borazanci EH, Downes M, Drebin JA, Tuveson DA, Ting DT, Moffitt R, Yeh JJ, Aguirre A, Evans R, et al. Vitamin D receptor agonist paricalcitol plus gemcitabine and nab-paclitaxel in patients with metastatic pancreatic cancer. Journal of Clinical Oncology. 38: TPS784-TPS784. DOI: 10.1200/Jco.2020.38.4_Suppl.Tps784  0.01
2020 Pessentheiner AR, Quach A, Al-Azzam N, Liu S, Downes M, Evans RM, Gordts PLMS. Adipose tissue heparan sulfate proteoglycans – critical regulators of adipocyte metabolism and glucose homeostasis The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03687  1
2020 Loomba R, Oh TG, Kim S, Singh S, Bettencourt R, Yu RT, Brenner DA, Sirlin CB, Downes M, Evans RM. Su1594 GUT MICROBIOME METAGENOMICS REVEALS FUNGAL MYCOBIOME ALTERATION IN NAFLD CIRRHOSIS WITH VALIDATION IN A GEOGRAPHICALLY INDEPENDENT COHORT Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)34047-6  1
2019 Sun X, Seidman JS, Zhao P, Troutman TD, Spann NJ, Que X, Zhou F, Liao Z, Pasillas M, Yang X, Magida JA, Kisseleva T, Brenner DA, Downes M, Evans RM, et al. Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis. Cell Metabolism. PMID 31761566 DOI: 10.1016/J.Cmet.2019.10.014  1
2019 Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, Borowsky AD, Bold RJ, Lara PN, Li JJ, Chen X, ... ... Evans RM, et al. RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype. Nature Communications. 10: 4621. PMID 31604910 DOI: 10.1038/S41467-019-12529-3  1
2019 Chang C, Loo CS, Zhao X, Solt LA, Liang Y, Bapat SP, Cho H, Kamenecka TM, Leblanc M, Atkins AR, Yu RT, Downes M, Burris TP, Evans RM, Zheng Y. The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 31455731 DOI: 10.1073/Pnas.1907563116  1
2019 Wang L, Mazagova M, Pan C, Yang S, Brandl K, Liu J, Reilly SM, Wang Y, Miao Z, Loomba R, Lu N, Guo Q, Liu J, Yu RT, Downes M, ... Evans RM, et al. YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31289229 DOI: 10.1073/Pnas.1904360116  1
2019 Shi Y, Gao W, Lytle NK, Huang P, Yuan X, Dann AM, Ridinger-Saison M, DelGiorno KE, Antal CE, Liang G, Atkins AR, Erikson G, Sun H, Meisenhelder J, Terenziani E, ... Evans RM, et al. Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring. Nature. PMID 30996350 DOI: 10.1038/S41586-019-1130-6  1
2019 Caussy C, Tripathi A, Humphrey G, Bassirian S, Singh S, Faulkner C, Bettencourt R, Rizo E, Richards L, Xu ZZ, Downes MR, Evans RM, Brenner DA, Sirlin CB, Knight R, et al. A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease. Nature Communications. 10: 1406. PMID 30926798 DOI: 10.1038/S41467-019-09455-9  1
2019 Auciello FR, Bulusu V, Oon C, Tait-Mulder J, Berry M, Bhattacharyya S, Tumanov S, Allen-Petersen BL, Link J, Kendsersky ND, Vringer E, Schug M, Novo D, Hwang RF, Evans RM, et al. A stromal lysolipid-autotaxin signaling axis promotes pancreatic tumor progression. Cancer Discovery. PMID 30837243 DOI: 10.1158/2159-8290.Cd-18-1212  1
2019 Fu T, Coulter S, Yoshihara E, Oh TG, Fang S, Cayabyab F, Zhu Q, Zhang T, Leblanc M, Liu S, He M, Waizenegger W, Gasser E, Schnabl B, Atkins AR, ... ... Evans RM, et al. FXR Regulates Intestinal Cancer Stem Cell Proliferation. Cell. 176: 1098-1112.e18. PMID 30794774 DOI: 10.1016/J.Cell.2019.01.036  1
2019 Ward JM, Stoyas CA, Switonski PM, Ichou F, Fan W, Collins B, Wall CE, Adanyeguh I, Niu C, Sopher BL, Kinoshita C, Morrison RS, Durr A, Muotri AR, Evans RM, et al. Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease. Cell Reports. 26: 1189-1202.e6. PMID 30699348 DOI: 10.1016/J.Celrep.2019.01.028  1
2019 Cui S, Li L, Yu RT, Downes M, Evans RM, Hulin JA, Makarenkova HP, Meech R. β-catenin is essential for differentiation of primary myoblasts via cooperation with MyoD and α-catenin. Development (Cambridge, England). PMID 30683662 DOI: 10.1242/dev.167080  1
2019 Hemmer MC, Wierer M, Schachtrup K, Downes M, Hübner N, Evans RM, Uhlenhaut NH. E47 modulates hepatic glucocorticoid action. Nature Communications. 10: 306. PMID 30659202 DOI: 10.1038/s41467-018-08196-5  1
2019 Talele NP, Liu H, Naxerova K, Pinter M, Incio J, Lee H, Shigeta K, Ho WW, Michelakos T, Hong TS, Clark JW, Murphy JE, Ryan DP, Deshpande V, Lillemoe KD, ... ... Evans RM, et al. Abstract A115: Use of angiotensin system inhibitors is associated with immune activation and longer survival in pancreatic ductal adenocarcinoma patients Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A115  1
2019 Liang G, Hah N, Shi Y, Truitt ML, Antal CE, Atkins AR, Fraser C, Banayo E, Bashi S, Dai Y, Sherman M, Liddle C, Yu RT, Hunter T, Han H, ... ... Evans RM, et al. Abstract A29: Bicompartmental regulation of disease-related gene networks by histone deacetylase inhibition curbs pancreatic cancer progression Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A29  1
2019 Liu H, Ho WW, Naxerova K, Grahovac J, Nia H, Chen I, Posada JM, Schanne DH, Pinter M, Crain J, Qi X, Clark JW, Hong TS, Ryan DP, Huang P, ... ... Evans RM, et al. Abstract A18: Angiotensin receptor blockers normalize the pancreatic ductal adenocarcinoma stroma by reprogramming carcinoma-associated fibroblasts Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A18  1
2019 Propper D, Han H, Hoff DV, Borazanci E, Reya T, Ghergurovich J, Pshenichnaya I, Antal C, Condjella R, Sharma S, O'Dwyer P, Littlewood T, Patel H, Saluja A, Velagapudi M, ... ... Evans R, et al. Abstract CT165: Phase II open label trial of minnelide™ in patients with chemotherapy refractory metastatic pancreatic cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Ct165  1
2019 Evans RM. Let's Raise a Glass to Sydney: In Memoriam (1927-2019) Cancer Research. 79: 2797-2797. DOI: 10.1158/0008-5472.Can-19-1267  0.01
2018 Senagolage MD, Sommars MA, Ramachandran K, Futtner CR, Omura Y, Allred AL, Wang J, Yang C, Procissi D, Evans RM, Han X, Bederman IR, Barish GD. Loss of Transcriptional Repression by BCL6 Confers Insulin Sensitivity in the Setting of Obesity. Cell Reports. 25: 3283-3298.e6. PMID 30566857 DOI: 10.1016/J.Celrep.2018.11.074  1
2018 Hong SH, Fang S, Lu BC, Nofsinger R, Kawakami Y, Castro GL, Yin Y, Lin C, Yu RT, Downes M, Izpisúa Belmonte JC, Shilatifard A, Evans RM. Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30254164 DOI: 10.1073/Pnas.1809480115  1
2018 Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, ... ... Evans RM, et al. Author Correction: Inflammation-induced IgA cells dismantle anti-liver cancer immunity. Nature. PMID 29973714 DOI: 10.1038/S41586-018-0304-Y  1
2018 Wei Z, Yoshihara E, He N, Hah N, Fan W, Pinto AFM, Huddy T, Wang Y, Ross B, Estepa G, Dai Y, Ding N, Sherman MH, Fang S, Zhao X, ... ... Evans RM, et al. Vitamin D Switches BAF Complexes to Protect β Cells. Cell. PMID 29754817 DOI: 10.1016/J.Cell.2018.04.013  1
2018 Magida JA, Evans RM. Rational application of macrophage-specific LXR agonists avoids the pitfalls of SREBP-induced lipogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29712848 DOI: 10.1073/pnas.1805128115  0.01
2018 Ahmadian M, Liu S, Reilly SM, Hah N, Fan W, Yoshihara E, Jha P, De Magalhaes Filho CD, Jacinto S, Gomez AV, Dai Y, Yu RT, Liddle C, Atkins AR, Auwerx J, ... ... Evans RM, et al. ERRγ Preserves Brown Fat Innate Thermogenic Activity. Cell Reports. 22: 2849-2859. PMID 29539415 DOI: 10.1016/J.Celrep.2018.02.061  1
2018 Fan W, He N, Lin CS, Wei Z, Hah N, Waizenegger W, He MX, Liddle C, Yu RT, Atkins AR, Downes M, Evans RM. ERRγ Promotes Angiogenesis, Mitochondrial Biogenesis, and Oxidative Remodeling in PGC1α/β-Deficient Muscle. Cell Reports. 22: 2521-2529. PMID 29514081 DOI: 10.1016/J.Celrep.2018.02.047  1
2018 De Magalhaes Filho CD, Henriquez B, Seah NE, Evans RM, Lapierre LR, Dillin A. Visible light reduces C. elegans longevity. Nature Communications. 9: 927. PMID 29500338 DOI: 10.1038/S41467-018-02934-5  1
2018 Shalom-Barak T, Liersemann J, Memari B, Flechner L, Devor C, Bernardo TM, Kim S, Matsumoto N, Friedman SL, Evans RM, White JH, Barak Y. Ligand-Dependent Corepressor (LCoR) Is A Rexinoid-Inhibited PPARγ-RXRα Coactivator. Molecular and Cellular Biology. PMID 29463649 DOI: 10.1128/Mcb.00107-17  1
2018 Chung VM, Borazanci EH, Jameson GS, Evans R, Downes M, Truitt ML, Patel H, Lowy AM, Roe D, Ansaldo K, Barrett MT, Korn RL, Caldwell L, Slethaug G, Hultsch R, et al. A SU2C catalyst randomized phase II trial of pembrolizumab with or without paricalcitol in patients with stage IV pancreatic cancer who have been placed in best possible response. Journal of Clinical Oncology. 36: TPS4154-TPS4154. DOI: 10.1200/Jco.2018.36.15_Suppl.Tps4154  0.01
2018 Evans R, Veen MV. Bivariate identities related to Chebyshev and Dickson polynomials over Fq Finite Fields and Their Applications. 49: 143-155. DOI: 10.1016/J.Ffa.2017.09.011  0.01
2017 Dickey AS, Sanchez DN, Arreola M, Sampat KR, Fan W, Arbez N, Akimov S, Van Kanegan MJ, Ohnishi K, Gilmore-Hall SK, Flores AL, Nguyen JM, Lomas N, Hsu CL, Lo DC, ... ... Evans RM, et al. PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis. Science Translational Medicine. 9. PMID 29212711 DOI: 10.1126/Scitranslmed.Aal2332  1
2017 Saison-Ridinger M, DelGiorno KE, Zhang T, Kraus A, French R, Jaquish D, Tsui C, Erikson G, Spike BT, Shokhirev MN, Liddle C, Yu RT, Downes M, Evans RM, Saghatelian A, et al. Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy. Plos One. 12: e0189051. PMID 29211796 DOI: 10.1371/Journal.Pone.0189051  1
2017 Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, ... ... Evans RM, et al. Erratum: Inflammation-induced IgA(+) cells dismantle anti-liver cancer immunity. Nature. PMID 29168501 DOI: 10.1038/Nature25028  1
2017 Hartmann P, Hochrath K, Horvath A, Chen P, Seebauer CT, Llorente C, Wang L, Alnouti Y, Fouts DE, Stärkel P, Loomba R, Coulter S, Liddle C, Yu RT, Ling L, ... ... Evans RM, et al. Modulation of the intestinal bile acid-FXR-FGF15 axis improves alcoholic liver disease in mice. Hepatology (Baltimore, Md.). PMID 29159825 DOI: 10.1002/Hep.29676  1
2017 Shalapour S, Lin XJ, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, ... Evans RM, et al. Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. Nature. 551: 340-345. PMID 29144460 DOI: 10.1038/Nature24302  1
2017 Cao Q, Zhao X, Bai J, Gery S, Sun H, Lin DC, Chen Q, Chen Z, Mack L, Yang H, Deng R, Shi X, Chong LW, Cho H, Xie J, ... ... Evans RM, et al. Circadian clock cryptochrome proteins regulate autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. PMID 29109286 DOI: 10.1073/Pnas.1619119114  1
2017 He N, Fan W, Henriquez B, Yu RT, Atkins AR, Liddle C, Zheng Y, Downes M, Evans RM. Metabolic control of regulatory T cell (Treg) survival and function by Lkb1. Proceedings of the National Academy of Sciences of the United States of America. PMID 29109251 DOI: 10.1073/Pnas.1715363114  1
2017 Wang J, He N, Zhang N, Quan D, Zhang S, Zhang C, Yu RT, Atkins AR, Zhu R, Yang C, Cui Y, Liddle C, Downes M, Xiao H, Zheng Y, ... ... Evans RM, et al. NCoR1 restrains thymic negative selection by repressing Bim expression to spare thymocytes undergoing positive selection. Nature Communications. 8: 959. PMID 29038463 DOI: 10.1038/S41467-017-00931-8  1
2017 Kriebs A, Jordan SD, Soto E, Henriksson E, Sandate CR, Vaughan ME, Chan AB, Duglan D, Papp SJ, Huber AL, Afetian ME, Yu RT, Zhao X, Downes M, Evans RM, et al. Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28751364 DOI: 10.1073/Pnas.1704955114  1
2017 Jordan SD, Kriebs A, Vaughan M, Duglan D, Fan W, Henriksson E, Huber AL, Papp SJ, Nguyen M, Afetian M, Downes M, Yu RT, Kralli A, Evans RM, Lamia KA. CRY1/2 Selectively Repress PPARδ and Limit Exercise Capacity. Cell Metabolism. 26: 243-255.e6. PMID 28683290 DOI: 10.1016/J.Cmet.2017.06.002  1
2017 Oral EA, Reilly SM, Gomez AV, Meral R, Butz L, Ajluni N, Chenevert TL, Korytnaya E, Neidert AH, Hench R, Rus D, Horowitz JF, Poirier B, Zhao P, Lehmann K, ... ... Evans RM, et al. Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes. Cell Metabolism. 26: 157-170.e7. PMID 28683283 DOI: 10.1016/J.Cmet.2017.06.006  1
2017 Gasser E, Moutos CP, Downes M, Evans RM. FGF1 - a new weapon to control type 2 diabetes mellitus. Nature Reviews. Endocrinology. PMID 28664920 DOI: 10.1038/nrendo.2017.78  1
2017 Evans RM. 30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Short reflections on the discovery of the mineralocorticoid receptor. The Journal of Endocrinology. 234: E1-E2. PMID 28634263 DOI: 10.1530/JOE-17-0287  0.01
2017 Liu H, Naxerova K, Pinter M, Incio J, Lee H, Shigeta K, Ho WW, Crain JA, Jacobson A, Michelakos T, Dias-Santos D, Zanconato A, Hong TS, Clark JW, Murphy JE, ... ... Evans RM, et al. Use of Angiotensin System Inhibitors is Associated with Immune Activation and Longer Survival in Non-Metastatic Pancreatic Ductal Adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28600474 DOI: 10.1158/1078-0432.Ccr-17-0256  1
2017 Chen S, Lu W, Yueh M, Rettenmeier E, Liu M, Paszek M, Auwerx J, Yu RT, Evans RM, Wang K, Karin M, Tukey RH. Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia (vol 114, pg E1432, 2017) Proceedings of the National Academy of Sciences of the United States of America. 114. PMID 28484028 DOI: 10.1073/Pnas.1705671114  1
2017 Fan W, Waizenegger W, Lin CS, Sorrentino V, He MX, Wall CE, Li H, Liddle C, Yu RT, Atkins AR, Auwerx J, Downes M, Evans RM. PPARδ Promotes Running Endurance by Preserving Glucose. Cell Metabolism. 25: 1186-1193.e4. PMID 28467934 DOI: 10.1016/j.cmet.2017.04.006  1
2017 Doktorova M, Zwarts I, Zutphen TV, Dijk TH, Bloks VW, Harkema L, Bruin A, Downes M, Evans RM, Verkade HJ, Jonker JW. Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia. Scientific Reports. 7: 846. PMID 28404991 DOI: 10.1038/s41598-017-00889-z  1
2017 Evan GI, Hah N, Littlewood TD, Sodir NM, Campos T, Downes M, Evans RM. Re-engineering the Pancreas Tumor Microenvironment: A "Regenerative Program" Hacked. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 23: 1647-1655. PMID 28373363 DOI: 10.1158/1078-0432.Ccr-16-3275  1
2017 Wu CC, Baiga TJ, Downes M, La Clair JJ, Atkins AR, Richard SB, Fan W, Stockley-Noel TA, Bowman ME, Noel JP, Evans RM. Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ. Proceedings of the National Academy of Sciences of the United States of America. PMID 28320959 DOI: 10.1073/Pnas.1621513114  1
2017 De Magalhaes Filho CD, Downes M, Evans RM. Farnesoid X Receptor an Emerging Target to Combat Obesity. Digestive Diseases (Basel, Switzerland). 35: 185-190. PMID 28249279 DOI: 10.1159/000450909  1
2017 Chen S, Lu W, Yueh MF, Rettenmeier E, Liu M, Auwerx J, Yu RT, Evans RM, Wang K, Karin M, Tukey RH. Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia. Proceedings of the National Academy of Sciences of the United States of America. PMID 28167773 DOI: 10.1073/Pnas.1700232114  1
2017 Sherman MH, Yu RT, Tseng TW, Sousa CM, Liu S, Truitt ML, He N, Ding N, Liddle C, Atkins AR, Leblanc M, Collisson EA, Asara JM, Kimmelman AC, Downes M, Evans RM, et al. Stromal cues regulate the pancreatic cancer epigenome and metabolome. Proceedings of the National Academy of Sciences of the United States of America. PMID 28096419 DOI: 10.1073/Pnas.1620164114  1
2017 Liu H, Pinter M, Incio J, Lee H, Ho W, Crain J, Naxerova K, Di M, Jacobson A, Santos DD, Zanconato A, Deshpande V, Lillemoe K, Castillos CFd, Downes M, ... Evans R, et al. Abstract 957: Use of angiotensin system inhibitors is associated with longer overall survival in pancreatic ductal adenocarcinoma patients who underwent pancreatectomy Cancer Research. 77: 957-957. DOI: 10.1158/1538-7445.Am2017-957  1
2017 Liang G, Yu R, Liddle C, Truitt M, Antal C, Atkins A, Banayo E, Downes M, Evans R. Abstract 5065: Harnessing epigenetic reprogramming by histone deacetylase inhibitor MS275 for pancreatic cancer therapy Cancer Research. 77: 5065-5065. DOI: 10.1158/1538-7445.Am2017-5065  1
2017 Aguirre AJ, Carter S, Camarda N, Ghazani A, Nowak J, Silva AD, Brais L, Ragon D, McCabe D, Marini L, Anderka K, Helvie K, Oliver N, Babic A, Shyn P, ... ... Evans R, et al. Abstract 3036: Real-time genomic characterization of metastatic pancreatic cancer to enable precision medicine Cancer Research. 77: 3036-3036. DOI: 10.1158/1538-7445.Am2017-3036  1
2016 Chung HK, Ryu D, Kim KS, Chang JY, Kim YK, Yi HS, Kang SG, Choi MJ, Lee SE, Jung SB, Ryu MJ, Kim SJ, Kweon GR, Kim H, Hwang JH, ... ... Evans RM, et al. Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis. The Journal of Cell Biology. PMID 27986797 DOI: 10.1083/Jcb.201607110  1
2016 Fu T, Zhao X, Evans RM. Liver Cancer Checks in When Bile Acid Clocks Out. Cancer Cell. 30: 827-828. PMID 27960079 DOI: 10.1016/J.Ccell.2016.11.012  1
2016 Fan W, Evans RM. Exercise Mimetics: Impact on Health and Performance. Cell Metabolism. PMID 27889389 DOI: 10.1016/j.cmet.2016.10.022  1
2016 Evans RM, Wan Y. Reply to "PPAR-γ regulates pharmacological but not physiological or pathological osteoclast formation". Nature Medicine. 22: 1205. PMID 27824815 DOI: 10.1038/Nm.4207  1
2016 Xia X, Kumru OS, Blaber SI, Middaugh CR, Li L, Ornitz DM, Suh JM, Atkins AR, Downes M, Evans RM, Tenorio CA, Bienkiewicz E, Blaber M. An S116R Phosphorylation Site Mutation in Human Fibroblast Growth Factor-1 Differentially Affects Mitogenic and Glucose-Lowering Activities. Journal of Pharmaceutical Sciences. 105: 3507-3519. PMID 27773526 DOI: 10.1016/J.Xphs.2016.09.005  1
2016 Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC. Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion. Nature. PMID 27706144 DOI: 10.1038/nature19851  1
2016 Fan W, Evans R. METABOLISM. The quest to burn fat, effortlessly and safely. Science (New York, N.Y.). 353: 749-50. PMID 27540151 DOI: 10.1126/science.aah6189  1
2016 De Magalhaes Filho CD, Downes M, Evans R. Bile Acid Analog Intercepts Liver Fibrosis. Cell. 166: 789. PMID 27518554 DOI: 10.1016/j.cell.2016.08.001  1
2016 Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC. Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion. Nature. PMID 27509858 DOI: 10.1038/Nature19084  1
2016 Eichenfield DZ, Troutman TD, Link VM, Lam MT, Cho H, Gosselin D, Spann NJ, Lesch HP, Tao J, Muto J, Gallo RL, Evans RM, Glass CK. Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages. Elife. 5. PMID 27462873 DOI: 10.7554/Elife.13024  1
2016 Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, Evans RM, et al. Corrigendum: ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nature Medicine. 22: 692. PMID 27270780 DOI: 10.1038/Nm0616-692B  1
2016 Zhao X, Hirota T, Han X, Cho H, Chong LW, Lamia K, Liu S, Atkins AR, Banayo E, Liddle C, Yu RT, Yates JR, Kay SA, Downes M, Evans RM. Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation. Cell. 165: 1644-57. PMID 27238018 DOI: 10.1016/J.Cell.2016.05.012  1
2016 Hulin JA, Nguyen TD, Cui S, Marri S, Yu RT, Downes M, Evans RM, Makarenkova H, Meech R. Barx2 and Pax7 regulate Axin2 expression in myoblasts by interaction with β-catenin and chromatin remodelling. Stem Cells (Dayton, Ohio). PMID 27144473 DOI: 10.1002/stem.2396  1
2016 Evans RM, Wall CE, Yu RT, Atkins AR, Downes M. Nuclear receptors and AMPK: can exercise mimetics cure diabetes? Journal of Molecular Endocrinology. PMID 27106806 DOI: 10.1530/JME-16-0073  1
2016 Yoshihara E, Wei Z, Lin CS, Fang S, Ahmadian M, Kida Y, Tseng T, Dai Y, Yu RT, Liddle C, Atkins AR, Downes M, Evans RM. ERRγ Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive β Cells. Cell Metabolism. 23: 622-34. PMID 27076077 DOI: 10.1016/J.Cmet.2016.03.005  1
2016 Heldin CH, Lu B, Evans R, Gutkind JS. Signals and Receptors. Cold Spring Harbor Perspectives in Biology. 8. PMID 27037414 DOI: 10.1101/Cshperspect.A005900  1
2016 Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, Evans RM, et al. ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nature Medicine. PMID 27019329 DOI: 10.1038/Nm.4070  1
2016 Zheng X, Boyer L, Jin M, Kim Y, Fan W, Bardy C, Berggren T, Evans RM, Gage FH, Hunter T. Alleviation of neuronal energy deficiency by mTOR inhibition as a treatment for mitochondria-related neurodegeneration. Elife. 5. PMID 27008180 DOI: 10.7554/Elife.13378  1
2016 Booth DR, Ding N, Parnell GP, Shahijanian F, Coulter S, Schibeci SD, Atkins AR, Stewart GJ, Evans RM, Downes M, Liddle C. Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-dependent autoimmune diseases. Genes and Immunity. PMID 26986782 DOI: 10.1038/gene.2016.12  1
2016 Liu W, Struik D, Nies VJ, Jurdzinski A, Harkema L, de Bruin A, Verkade HJ, Downes M, Evans RM, van Zutphen T, Jonker JW. Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 26858440 DOI: 10.1073/pnas.1525093113  1
2016 Hah N, Sherman MH, Yu RT, Downes M, Evans RM. Targeting Transcriptional and Epigenetic Reprogramming in Stromal Cells in Fibrosis and Cancer. Cold Spring Harbor Symposia On Quantitative Biology. PMID 26801159 DOI: 10.1101/Sqb.2015.80.027185  1
2016 Zheng X, Boyer L, Jin M, Kim Y, Fan W, Bardy C, Berggren T, Evans RM, Gage FH, Hunter T. Author response: Alleviation of neuronal energy deficiency by mTOR inhibition as a treatment for mitochondria-related neurodegeneration Elife. DOI: 10.7554/Elife.13378.031  1
2016 Eichenfield DZ, Troutman TD, Link VM, Lam MT, Cho H, Gosselin D, Spann NJ, Lesch HP, Tao J, Muto J, Gallo RL, Evans RM, Glass CK. Author response: Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages Elife. DOI: 10.7554/Elife.13024.022  1
2016 Sherman MH, Evans R. Abstract IA04: Stromal regulation of pancreatic cancer epigenome and metabolome Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-Ia04  1
2016 Sherman MH, Evans RM. Abstract B03: Control of pancreatic cancer metabolism and histone acetylation by the tumor microenvironment Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-B03  1
2016 Sherman MH, Evans RM. Abstract IA13: Stromal regulation and therapeutic targeting of the pancreatic cancer epigenome Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-Ia13  1
2016 Ridinger M, Evans RM, Saghatelian A, Lowy AM, Wahl GM. Abstract B24: p53 mediates reprograming of cancer-associated fibroblasts in pancreatic cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-B24  1
2015 Nies VJ, Sancar G, Liu W, van Zutphen T, Struik D, Yu RT, Atkins AR, Evans RM, Jonker JW, Downes MR. Fibroblast Growth Factor Signaling in Metabolic Regulation. Frontiers in Endocrinology. 6: 193. PMID 26834701 DOI: 10.3389/fendo.2015.00193  1
2015 Ding N, Hah N, Yu RT, Sherman MH, Benner C, Leblanc M, He M, Liddle C, Downes M, Evans RM. BRD4 is a novel therapeutic target for liver fibrosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26644586 DOI: 10.1073/Pnas.1522163112  1
2015 Evans RM, Brooke EJ, Wehlin SA, Nomerotskaia E, Sargent F, Carr SB, Phillips SE, Armstrong FA. Mechanism of hydrogen activation by [NiFe] hydrogenases. Nature Chemical Biology. PMID 26619250 DOI: 10.1038/nchembio.1976  1
2015 Bapat SP, Myoung Suh J, Fang S, Liu S, Zhang Y, Cheng A, Zhou C, Liang Y, LeBlanc M, Liddle C, Atkins AR, Yu RT, Downes M, Evans RM, Zheng Y. Depletion of fat-resident Treg cells prevents age-associated insulin resistance. Nature. PMID 26580014 DOI: 10.1038/Nature16151  1
2015 Evans RM, Martin OV, Faust M, Kortenkamp A. Should the scope of human mixture risk assessment span legislative/regulatory silos for chemicals? The Science of the Total Environment. PMID 26573369 DOI: 10.1016/j.scitotenv.2015.10.162  1
2015 Schieber AM, Lee YM, Chang MW, Leblanc M, Collins B, Downes M, Evans RM, Ayres JS. Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling. Science (New York, N.Y.). 350: 558-63. PMID 26516283 DOI: 10.1126/Science.Aac6468  1
2015 Evans RM, Scholze M, Kortenkamp A. Examining the feasibility of mixture risk assessment: A case study using a tiered approach with data of 67 pesticides from the Joint FAO/WHO Meeting on Pesticide Residues (JMPR). Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 84: 260-9. PMID 26344759 DOI: 10.1016/j.fct.2015.08.015  1
2015 Ranjit S, Dvornikov A, Stakic M, Hong SH, Levi M, Evans RM, Gratton E. Imaging Fibrosis and Separating Collagens using Second Harmonic Generation and Phasor Approach to Fluorescence Lifetime Imaging. Scientific Reports. 5: 13378. PMID 26293987 DOI: 10.1038/Srep13378  1
2015 Arensman MD, Nguyen P, Kershaw KM, Lay AR, Ostertag-Hill CA, Sherman MH, Downes M, Liddle C, Evans RM, Dawson DW. Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer. Molecular Cancer Research : McR. PMID 26224368 DOI: 10.1158/1541-7786.Mcr-15-0204  1
2015 Wall CE, Whyte J, Suh JM, Fan W, Collins B, Liddle C, Yu RT, Atkins AR, Naviaux JC, Li K, Bright AT, Alaynick WA, Downes M, Naviaux RK, Evans RM. High-fat diet and FGF21 cooperatively promote aerobic thermogenesis in mtDNA mutator mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 26124126 DOI: 10.1073/Pnas.1509930112  1
2015 Murphy BJ, Hidalgo R, Roessler MM, Evans RM, Ash PA, Myers WK, Vincent KA, Armstrong FA. Discovery of Dark pH-Dependent H(+) Migration in a [NiFe]-Hydrogenase and Its Mechanistic Relevance: Mobilizing the Hydrido Ligand of the Ni-C Intermediate. Journal of the American Chemical Society. PMID 26103582 DOI: 10.1021/jacs.5b03182  1
2015 Kim JA, Roy RR, Zhong H, Alaynick WA, Embler E, Jang C, Gomez G, Sonoda T, Evans RM, Edgerton VR. Pparδ preserves a high resistance to fatigue in the mouse medial gastrocnemius after spinal cord transection. Muscle & Nerve. PMID 26044200 DOI: 10.1002/Mus.24723  1
2015 Mounsey RB, Martin HL, Nelson MC, Evans RM, Teismann P. The effect of neuronal conditional knock-out of peroxisome proliferator-activated receptors in the MPTP mouse model of Parkinson's disease. Neuroscience. 300: 576-84. PMID 26028469 DOI: 10.1016/j.neuroscience.2015.05.048  1
2015 Fan W, Evans RM. Turning up the heat on membrane fluidity. Cell. 161: 962-3. PMID 26000475 DOI: 10.1016/j.cell.2015.04.046  1
2015 Jo YS, Ryu D, Maida A, Wang X, Evans RM, Schoonjans K, Auwerx J. Phosphorylation of the nuclear receptor co-repressor 1 by protein kinase B (PKB/Akt) switches its co-repressor targets in the liver. Hepatology (Baltimore, Md.). PMID 25998209 DOI: 10.1002/Hep.27907  1
2015 Evans RM, Hall CA, Simha RA, Welsh TS. Classical XY model with conserved angular momentum is an archetypal non-Newtonian fluid. Physical Review Letters. 114: 138301. PMID 25884140  1
2015 Kida YS, Kawamura T, Wei Z, Sogo T, Jacinto S, Shigeno A, Kushige H, Yoshihara E, Liddle C, Ecker JR, Yu RT, Atkins AR, Downes M, Evans RM. ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency. Cell Stem Cell. 16: 547-55. PMID 25865501 DOI: 10.1016/J.Stem.2015.03.001  1
2015 Pei L, Mu Y, Leblanc M, Alaynick W, Barish GD, Pankratz M, Tseng TW, Kaufman S, Liddle C, Yu RT, Downes M, Pfaff SL, Auwerx J, Gage FH, Evans RM. Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolism. Cell Metabolism. 21: 628-36. PMID 25863252 DOI: 10.1016/J.Cmet.2015.03.004  1
2015 Hutchison AM, Topliss C, Beard D, Evans RM, Williams P. The treatment of a rupture of the Achilles tendon using a dedicated management programme. The Bone & Joint Journal. 97: 510-5. PMID 25820890 DOI: 10.1302/0301-620X.97B4.35314  1
2015 Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, ... ... Evans RM, et al. Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature. 520: 388. PMID 25739500 DOI: 10.1038/Nature14304  1
2015 Wang T, McDonald C, Petrenko NB, Leblanc M, Wang T, Giguere V, Evans RM, Patel VV, Pei L. Estrogen-related receptor α (ERRα) and ERRγ are essential coordinators of cardiac metabolism and function. Molecular and Cellular Biology. 35: 1281-98. PMID 25624346 DOI: 10.1128/Mcb.01156-14  1
2015 Reilly SM, Ahmadian M, Zamarron BF, Chang L, Uhm M, Poirier B, Peng X, Krause DM, Korytnaya E, Neidert A, Liddle C, Yu RT, Lumeng CN, Oral EA, Downes M, ... Evans RM, et al. A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis. Nature Communications. 6: 6047. PMID 25581158 DOI: 10.1038/Ncomms7047  1
2015 Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, ... ... Evans RM, et al. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nature Medicine. 21: 159-65. PMID 25559344 DOI: 10.1038/Nm.3760  1
2015 Fan W, Evans R. PPARs and ERRs: molecular mediators of mitochondrial metabolism. Current Opinion in Cell Biology. 33: 49-54. PMID 25486445 DOI: 10.1016/j.ceb.2014.11.002  1
2015 Morinaga H, Mayoral R, Heinrichsdorff J, Osborn O, Franck N, Hah N, Walenta E, Bandyopadhyay G, Pessentheiner AR, Chi TJ, Chung H, Bogner-Strauss JG, Evans RM, Olefsky JM, Oh da Y. Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice. Diabetes. 64: 1120-30. PMID 25315009 DOI: 10.2337/Db14-1238  1
2015 Cao Q, Zhao X, Gery S, Chen Z, Deng R, Sun H, Lin D, Zhao Z, Said JW, Li Q, Muschen M, Evans RM, Koeffler HP. Circadian Clock Protein CRY Controls B-Cell Intrinsic Tolerance Blood. 126: 1029-1029. DOI: 10.1182/Blood.V126.23.1029.1029  0.01
2015 Sherman MH, Ding N, Collisson EA, Downes M, Evans RM. Abstract IA9: Vitamin D: Shining light on pancreatic cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-Ia9  1
2015 Ridinger M, Kraus A, Cox M, Wade M, Liddle C, Downes M, Evans R, Wahl G. Abstract B10: Function and therapeutic implications of p53 in the stroma of pancreatic cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B10  1
2015 Sherman MH, Collisson E, Downes M, Evans RM. Abstract A42: Paracrine regulation of the pancreatic cancer epigenome Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A42  1
2015 Evans RM. Abstract RAOS15-03: Pancreatic tumor stroma as a therapeutic target Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Raos15-03  0.01
2015 Kay C, Opher M, Evans RM. Global trends of CME deflections based on CME and solar parameters Astrophysical Journal. 805. DOI: 10.1088/0004-637X/805/2/168  1
2015 Yueh MF, Taniguchi K, Chen S, Evans RM, Hammock BD, Karin M, Tukey RH. Erratum: The commonly used antimicrobial additive triclosan is a liver tumor promoter (Proc Natl Acad Sci USA (2014) 111 (17200-17205) DOI: 10.1073/pnas.1419119111) Proceedings of the National Academy of Sciences of the United States of America. 112. DOI: 10.1073/Pnas.1423844112  1
2015 Ranjit S, Dvornikov A, Stakic M, Hong SH, Levi M, Evans RM, Gratton E. Imaging Fibrosis and Separating Collagens using Second Harmonic Generation and Phasor Approach to Fluorescence Lifetime Imaging Scientific Reports. 5. DOI: 10.1038/srep13378  1
2015 Jian LK, Macneice PJ, Taktakishvili A, Odstrcil D, Jackson B, Yu HS, Riley P, Sokolov IV, Evans RM. Validation for solar wind prediction at Earth: Comparison of coronal and heliospheric models installed at the CCMC Space Weather. 13: 316-338. DOI: 10.1002/2015SW001174  1
2014 McKenna NJ, Evans RM, O'Malley BW. Nuclear Receptor Signaling: a home for nuclear receptor and coregulator signaling research. Nuclear Receptor Signaling. 12: e006. PMID 25614732 DOI: 10.1621/nrs.12006  1
2014 Yueh MF, Taniguchi K, Chen S, Evans RM, Hammock BD, Karin M, Tukey RH. The commonly used antimicrobial additive triclosan is a liver tumor promoter. Proceedings of the National Academy of Sciences of the United States of America. 111: 17200-5. PMID 25404284 DOI: 10.1073/Pnas.1419119111  1
2014 Williamson JJ, Evans RM. Measuring local volume fraction, long-wavelength correlations, and fractionation in a phase-separating polydisperse fluid. The Journal of Chemical Physics. 141: 164901. PMID 25362335 DOI: 10.1063/1.4897560  1
2014 Sherman MH, Yu RT, Engle DD, Ding N, Atkins AR, Tiriac H, Collisson EA, Connor F, Van Dyke T, Kozlov S, Martin P, Tseng TW, Dawson DW, Donahue TR, Masamune A, ... ... Evans RM, et al. Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy. Cell. 159: 80-93. PMID 25259922 DOI: 10.1016/J.Cell.2014.08.007  1
2014 Takada H, Saito Y, Mituyama T, Wei Z, Yoshihara E, Jacinto S, Downes M, Evans RM, Kida YS. Methylome, transcriptome, and PPAR(γ) cistrome analyses reveal two epigenetic transitions in fat cells. Epigenetics : Official Journal of the Dna Methylation Society. 9: 1195-206. PMID 25093444 DOI: 10.4161/Epi.29856  1
2014 Korf K, Wodrich H, Haschke A, Ocampo C, Harder L, Gieseke F, Pollmann A, Dierck K, Prall S, Staege H, Ma H, Horstmann MA, Evans RM, Sternsdorf T. The PML domain of PML-RARα blocks senescence to promote leukemia. Proceedings of the National Academy of Sciences of the United States of America. 111: 12133-8. PMID 25092303 DOI: 10.1073/pnas.1412944111  1
2014 Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, ... ... Evans RM, et al. Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature. 513: 436-9. PMID 25043058 DOI: 10.1038/Nature13540  1
2014 Daniel B, Nagy G, Hah N, Horvath A, Czimmerer Z, Poliska S, Gyuris T, Keirsse J, Gysemans C, Van Ginderachter JA, Balint BL, Evans RM, Barta E, Nagy L. The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages. Genes & Development. 28: 1562-77. PMID 25030696 DOI: 10.1101/Gad.242685.114  1
2014 Behiry EM, Evans RM, Guo J, Loveridge EJ, Allemann RK. Loop interactions during catalysis by dihydrofolate reductase from Moritella profunda. Biochemistry. 53: 4769-74. PMID 25014120 DOI: 10.1021/Bi500508Z  1
2014 Oh da Y, Walenta E, Akiyama TE, Lagakos WS, Lackey D, Pessentheiner AR, Sasik R, Hah N, Chi TJ, Cox JM, Powels MA, Di Salvo J, Sinz C, Watkins SM, Armando AM, ... ... Evans RM, et al. A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice. Nature Medicine. 20: 942-7. PMID 24997608 DOI: 10.1038/Nm.3614  1
2014 Perros P, Boelaert K, Colley S, Evans C, Evans RM, Gerrard Ba G, Gilbert J, Harrison B, Johnson SJ, Giles TE, Moss L, Lewington V, Newbold K, Taylor J, Thakker RV, et al. Guidelines for the management of thyroid cancer. Clinical Endocrinology. 81: 1-122. PMID 24989897 DOI: 10.1111/cen.12515  1
2014 Zhuang L, Hulin JA, Gromova A, Tran Nguyen TD, Yu RT, Liddle C, Downes M, Evans RM, Makarenkova HP, Meech R. Barx2 and Pax7 have antagonistic functions in regulation of wnt signaling and satellite cell differentiation. Stem Cells (Dayton, Ohio). 32: 1661-73. PMID 24753152 DOI: 10.1002/stem.1674  1
2014 Zhao X, Cho H, Yu RT, Atkins AR, Downes M, Evans RM. Nuclear receptors rock around the clock. Embo Reports. 15: 518-28. PMID 24737872 DOI: 10.1002/Embr.201338271  1
2014 Lu B, Bridges D, Yang Y, Fisher K, Cheng A, Chang L, Meng ZX, Lin JD, Downes M, Yu RT, Liddle C, Evans RM, Saltiel AR. Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity. Diabetes. 63: 2935-48. PMID 24722244 DOI: 10.2337/Db13-1531  1
2014 Evans RM, Mangelsdorf DJ. Nuclear Receptors, RXR, and the Big Bang. Cell. 157: 255-66. PMID 24679540 DOI: 10.1016/j.cell.2014.03.012  1
2014 Evans RM, Armstrong FA. Electrochemistry of metalloproteins: protein film electrochemistry for the study of E. coli [NiFe]-hydrogenase-1. Methods in Molecular Biology (Clifton, N.J.). 1122: 73-94. PMID 24639254 DOI: 10.1007/978-1-62703-794-5_6  1
2014 Hong SH, Ahmadian M, Yu RT, Atkins AR, Downes M, Evans RM. Nuclear receptors and metabolism: from feast to famine. Diabetologia. 57: 860-7. PMID 24619218 DOI: 10.1007/S00125-014-3209-9  1
2014 Liu S, Evans RM. Metabolism: Tick, tock, a high-fat clock. Nature Reviews. Endocrinology. 10: 191-2. PMID 24590185 DOI: 10.1038/Nrendo.2014.23  1
2014 Kneževi? M, Evans RM. Numerical comparison of a constrained path ensemble and a driven quasisteady state. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 89: 012132. PMID 24580197  0.01
2014 d'Uscio LV, He T, Santhanam AV, Tai LJ, Evans RM, Katusic ZS. Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-δ gene. American Journal of Physiology. Heart and Circulatory Physiology. 306: H1001-10. PMID 24486511 DOI: 10.1152/ajpheart.00761.2013  1
2014 Evans RM. Abstract SY04-04: Vitamin D receptor stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Sy04-04  0.01
2014 Lister R, Pelizzola M, Kida YS, Hawkins RD, Nery JR, Hon G, Antosiewicz-Bourget J, O'Malley R, Castanon R, Klugman S, Downes M, Yu R, Stewart R, Ren B, Thomson JA, ... Evans RM, et al. Corrigendum: Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells Nature. 514: 126. DOI: 10.1038/Nature13843  1
2013 Fan W, Atkins AR, Yu RT, Downes M, Evans RM. Road to exercise mimetics: targeting nuclear receptors in skeletal muscle. Journal of Molecular Endocrinology. 51: T87-T100. PMID 24280961 DOI: 10.1530/JME-13-0258  1
2013 Evans RM. Journal of Molecular Endocrinology 25th anniversary special issue. Journal of Molecular Endocrinology. 51: E1-3. PMID 24280960 DOI: 10.1530/JME-13-0257  1
2013 Hong SH, Dvorak-Ewell M, Stevens HY, Barish GD, Castro GL, Nofsinger R, Frangos JA, Shoback D, Evans RM. Rescue of a primary myelofibrosis model by retinoid-antagonist therapy. Proceedings of the National Academy of Sciences of the United States of America. 110: 18820-5. PMID 24191050 DOI: 10.1073/Pnas.1318974110  1
2013 Ding N, Liddle C, Evans RM, Downes M. Hepatic actions of vitamin D receptor ligands: a sunshine option for chronic liver disease? Expert Review of Clinical Pharmacology. 6: 597-9. PMID 24164608 DOI: 10.1586/17512433.2013.841078  1
2013 Fang S, Evans RM. Microbiology: Wealth management in the gut. Nature. 500: 538-9. PMID 23985869 DOI: 10.1038/500538a  1
2013 Kittayaruksakul S, Zhao W, Xu M, Ren S, Lu J, Wang J, Downes M, Evans RM, Venkataramanan R, Chatsudthipong V, Xie W. Identification of three novel natural product compounds that activate PXR and CAR and inhibit inflammation. Pharmaceutical Research. 30: 2199-208. PMID 23896737 DOI: 10.1007/S11095-013-1101-9  1
2013 Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, Tanaka-Oishi Y, Benner C, Kaikkonen MU, Kim AS, Kosaka M, Lee CY, Watt A, Grossman TR, Rosenfeld MG, Evans RM, et al. Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature. 498: 511-5. PMID 23728303 DOI: 10.1038/Nature12209  1
2013 Du L, Bergsneider M, Mirsadraei L, Young SH, Jonker JW, Downes M, Yong WH, Evans RM, Heaney AP. Evidence for orphan nuclear receptor TR4 in the etiology of Cushing disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 8555-60. PMID 23653479 DOI: 10.1073/Pnas.1306182110  1
2013 Ahmadian M, Suh JM, Hah N, Liddle C, Atkins AR, Downes M, Evans RM. PPARγ signaling and metabolism: the good, the bad and the future. Nature Medicine. 19: 557-66. PMID 23652116 DOI: 10.1038/Nm.3159  1
2013 Ding N, Yu RT, Subramaniam N, Sherman MH, Wilson C, Rao R, Leblanc M, Coulter S, He M, Scott C, Lau SL, Atkins AR, Barish GD, Gunton JE, Liddle C, ... ... Evans RM, et al. A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response. Cell. 153: 601-13. PMID 23622244 DOI: 10.1016/J.Cell.2013.03.028  1
2013 Hutchison AM, Pallister I, Evans RM, Bodger O, Topliss CJ, Williams P, Beard DJ. Intense pulsed light treatment of chronic mid-body Achilles tendinopathy: A double blind randomised placebo-controlled trial. The Bone & Joint Journal. 95: 504-9. PMID 23539702 DOI: 10.1302/0301-620X.95B4.30558  1
2013 Martin HL, Mounsey RB, Sathe K, Mustafa S, Nelson MC, Evans RM, Teismann P. A peroxisome proliferator-activated receptor-δ agonist provides neuroprotection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. Neuroscience. 240: 191-203. PMID 23500098 DOI: 10.1016/j.neuroscience.2013.02.058  1
2013 Evans RM, Parkin A, Roessler MM, Murphy BJ, Adamson H, Lukey MJ, Sargent F, Volbeda A, Fontecilla-Camps JC, Armstrong FA. Principles of sustained enzymatic hydrogen oxidation in the presence of oxygen--the crucial influence of high potential Fe-S clusters in the electron relay of [NiFe]-hydrogenases. Journal of the American Chemical Society. 135: 2694-707. PMID 23398301 DOI: 10.1021/Ja311055D  1
2013 Reilly SM, Chiang SH, Decker SJ, Chang L, Uhm M, Larsen MJ, Rubin JR, Mowers J, White NM, Hochberg I, Downes M, Yu RT, Liddle C, Evans RM, Oh D, et al. An inhibitor of the protein kinases TBK1 and IKK-É› improves obesity-related metabolic dysfunctions in mice. Nature Medicine. 19: 313-21. PMID 23396211 DOI: 10.1038/Nm.3082  1
2013 Zhao X, Cho H, Evans RM. SRF'ing around the clock. Cell. 152: 381-2. PMID 23374332 DOI: 10.1016/J.Cell.2013.01.028  1
2013 Chao LC, Soto E, Hong C, Ito A, Pei L, Chawla A, Conneely OM, Tangirala RK, Evans RM, Tontonoz P. Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice. Journal of Lipid Research. 54: 806-15. PMID 23288947 DOI: 10.1194/Jlr.M034157  1
2013 Krug AK, Kolde R, Gaspar JA, Rempel E, Balmer NV, Meganathan K, Vojnits K, Baquié M, Waldmann T, Ensenat-Waser R, Jagtap S, Evans RM, Julien S, Peterson H, Zagoura D, et al. Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach. Archives of Toxicology. 87: 123-43. PMID 23179753 DOI: 10.1007/s00204-012-0967-3  1
2013 Uhlenhaut NH, Barish GD, Yu RT, Downes M, Karunasiri M, Liddle C, Schwalie P, Hübner N, Evans RM. Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes. Molecular Cell. 49: 158-71. PMID 23159735 DOI: 10.1016/j.molcel.2012.10.013  1
2013 Loveridge EJ, Matthews SM, Williams C, Whittaker SB, Günther UL, Evans RM, Dawson WM, Crump MP, Allemann RK. Aliphatic (1)H, (13)C and (15)N chemical shift assignments of dihydrofolate reductase from the psychropiezophile Moritella profunda in complex with NADP(+) and folate. Biomolecular Nmr Assignments. 7: 61-4. PMID 22415546 DOI: 10.1007/S12104-012-9378-X  1
2013 Korf K, Wodrich H, Haschke A, Evans RM, Sternsdorf TM. The Acute Promyelocytic Leukemia-Oncoprotein PML-Raralpha Blocks Senescence and Disrupts The Atrx/Daxx Chromatin Remodeling Complex To Promote Leukemia Blood. 122: 1267-1267. DOI: 10.1182/BLOOD.V122.21.1267.1267  0.01
2013 Evans RM, Johnson JA, Garman AN, Kletke P. Meeting the challenge: Career development and targeted enrichment programs insuring a viable pipeline Sage Open. 3: 1-11. DOI: 10.1177/2158244013484475  1
2013 Kozarev KA, Evans RM, Schwadron NA, Dayeh MA, Opher M, Korreck KE, Van Der Holst B. Global numerical modeling of energetic proton acceleration in a coronal mass ejection traveling through the solar corona Astrophysical Journal. 778. DOI: 10.1088/0004-637X/778/1/43  1
2013 Kay C, Opher M, Evans RM. Forecasting a coronal mass ejection's altered trajectory: ForeCAT Astrophysical Journal. 775. DOI: 10.1088/0004-637X/775/1/5  1
2013 Sokolov IV, Van Der Holst B, Oran R, Downs C, Roussev II, Jin M, Manchester WB, Evans RM, Gombosi TI. Magnetohydrodynamic waves and coronal heating: Unifying empirical and mhd turbulence models Astrophysical Journal. 764. DOI: 10.1088/0004-637X/764/1/23  1
2013 Evans RM. Foreword Translational Endocrinology of Bone. ix-x. DOI: 10.1016/B978-0-12-415784-2.06001-2  1
2013 Evans RM, Pulkkinen AA, Zheng Y, Leila Mays M, Taktakishvili A, Kuznetsova MM, Hesse M. The SCORE scale: A coronal mass ejection typification system based on speed Space Weather. 11: 333-334. DOI: 10.1002/swe.20058  1
2013 Gardner WA, Blount JL, Golec JR, Jones WA, Hu XP, Talamas EJ, Evans RM, Dong X, Ray CH, Buntin GD, Gerardo NM, Couret J. Discovery of paratelenomus saccharalis (Dodd) (Hymenoptera: Platygastridae), an egg parasitoid of megacopta cribrarla F. (Hemiptera: Plataspidae) in its expanded North American range Journal of Entomological Science. 48: 355-359.  1
2012 Zhang Y, Xie Y, Berglund ED, Coate KC, He TT, Katafuchi T, Xiao G, Potthoff MJ, Wei W, Wan Y, Yu RT, Evans RM, Kliewer SA, Mangelsdorf DJ. The starvation hormone, fibroblast growth factor-21, extends lifespan in mice. Elife. 1: e00065. PMID 23066506 DOI: 10.7554/Elife.00065  1
2012 Chao LC, Wroblewski K, Ilkayeva OR, Stevens RD, Bain J, Meyer GA, Schenk S, Martinez L, Vergnes L, Narkar VA, Drew BG, Hong C, Boyadjian R, Hevener AL, Evans RM, et al. Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization. Journal of Lipid Research. 53: 2610-9. PMID 23028113 DOI: 10.1194/Jlr.M029355  1
2012 Williamson JJ, Evans RM. Spinodal fractionation in a polydisperse square-well fluid. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 86: 011405. PMID 23005415  1
2012 Li T, Yu RT, Atkins AR, Downes M, Tukey RH, Evans RM. Targeting the pregnane X receptor in liver injury. Expert Opinion On Therapeutic Targets. 16: 1075-83. PMID 22913318 DOI: 10.1517/14728222.2012.715634  1
2012 Evans RM, Scholze M, Kortenkamp A. Additive mixture effects of estrogenic chemicals in human cell-based assays can be influenced by inclusion of chemicals with differing effect profiles. Plos One. 7: e43606. PMID 22912892 DOI: 10.1371/journal.pone.0043606  1
2012 Ito K, Carracedo A, Weiss D, Arai F, Ala U, Avigan DE, Schafer ZT, Evans RM, Suda T, Lee CH, Pandolfi PP. A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. Nature Medicine. 18: 1350-8. PMID 22902876 DOI: 10.1038/Nm.2882  1
2012 Roessler MM, Evans RM, Davies RA, Harmer J, Armstrong FA. EPR spectroscopic studies of the Fe-S clusters in the O2-tolerant [NiFe]-hydrogenase Hyd-1 from Escherichia coli and characterization of the unique [4Fe-3S] cluster by HYSCORE. Journal of the American Chemical Society. 134: 15581-94. PMID 22900997 DOI: 10.1021/ja307117y  1
2012 Yueh MF, Li T, Evans RM, Hammock B, Tukey RH. Triclocarban mediates induction of xenobiotic metabolism through activation of the constitutive androstane receptor and the estrogen receptor alpha. Plos One. 7: e37705. PMID 22761658 DOI: 10.1371/Journal.Pone.0037705  1
2012 Iwaisako K, Haimerl M, Paik YH, Taura K, Kodama Y, Sirlin C, Yu E, Yu RT, Downes M, Evans RM, Brenner DA, Schnabl B. Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist. Proceedings of the National Academy of Sciences of the United States of America. 109: E1369-76. PMID 22538808 DOI: 10.1073/Pnas.1202464109  1
2012 Jonker JW, Suh JM, Atkins AR, Ahmadian M, Li P, Whyte J, He M, Juguilon H, Yin YQ, Phillips CT, Yu RT, Olefsky JM, Henry RR, Downes M, Evans RM. A PPARγ-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis. Nature. 485: 391-4. PMID 22522926 DOI: 10.1038/Nature10998  1
2012 Barish GD, Yu RT, Karunasiri MS, Becerra D, Kim J, Tseng TW, Tai LJ, Leblanc M, Diehl C, Cerchietti L, Miller YI, Witztum JL, Melnick AM, Dent AL, Tangirala RK, ... Evans RM, et al. The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis. Cell Metabolism. 15: 554-62. PMID 22465074 DOI: 10.1016/J.Cmet.2012.02.012  1
2012 Cho H, Zhao X, Hatori M, Yu RT, Barish GD, Lam MT, Chong LW, DiTacchio L, Atkins AR, Glass CK, Liddle C, Auwerx J, Downes M, Panda S, Evans RM. Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β. Nature. 485: 123-7. PMID 22460952 DOI: 10.1038/Nature11048  1
2012 Evans R. Wylie Walker Vale Jr (1941-2012). Nature. 483: 542. PMID 22460892 DOI: 10.1038/483542a  1
2012 Matsakas A, Yadav V, Lorca S, Evans RM, Narkar VA. Revascularization of ischemic skeletal muscle by estrogen-related receptor-γ. Circulation Research. 110: 1087-96. PMID 22415017 DOI: 10.1161/CIRCRESAHA.112.266478  1
2012 Subramaniam N, Sherman MH, Rao R, Wilson C, Coulter S, Atkins AR, Evans RM, Liddle C, Downes M. Metformin-mediated Bambi expression in hepatic stellate cells induces prosurvival Wnt/β-catenin signaling. Cancer Prevention Research (Philadelphia, Pa.). 5: 553-61. PMID 22406377 DOI: 10.1158/1940-6207.Capr-12-0053  1
2012 Li MD, Ruan HB, Singh JP, Zhao L, Zhao T, Azarhoush S, Wu J, Evans RM, Yang X. O-GlcNAc transferase is involved in glucocorticoid receptor-mediated transrepression. The Journal of Biological Chemistry. 287: 12904-12. PMID 22371499 DOI: 10.1074/Jbc.M111.303792  1
2012 Chen S, Yueh MF, Evans RM, Tukey RH. Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in humanized UGT1 mice. Hepatology (Baltimore, Md.). 56: 658-67. PMID 22371261 DOI: 10.1002/Hep.25671  1
2012 Noreault-Conti TL, Fellows A, Jacobs JM, Trask HW, Strom SC, Evans RM, Wrighton SA, Sinclair PR, Sinclair JF, Nichols RC. Arsenic decreases RXRα-dependent transcription of CYP3A and suppresses immune regulators in hepatocytes. International Immunopharmacology. 12: 651-6. PMID 22310326 DOI: 10.1016/j.intimp.2012.01.008  1
2012 Warren JM, Iversen CM, Garten CT, Norby RJ, Childs J, Brice D, Evans RM, Gu L, Thornton P, Weston DJ. Timing and magnitude of C partitioning through a young loblolly pine (Pinus taeda L.) stand using 13C labeling and shade treatments. Tree Physiology. 32: 799-813. PMID 22210530 DOI: 10.1093/Treephys/Tpr129  1
2012 Shimozaki K, Zhang CL, Suh H, Denli AM, Evans RM, Gage FH. SRY-box-containing gene 2 regulation of nuclear receptor tailless (Tlx) transcription in adult neural stem cells. The Journal of Biological Chemistry. 287: 5969-78. PMID 22194602 DOI: 10.1074/Jbc.M111.290403  1
2012 Sherman MH, Downes M, Evans RM. Nuclear receptors as modulators of the tumor microenvironment. Cancer Prevention Research (Philadelphia, Pa.). 5: 3-10. PMID 22135047 DOI: 10.1158/1940-6207.Capr-11-0528  1
2012 Panopoulos AD, Yanes O, Ruiz S, Kida YS, Diep D, Tautenhahn R, Herrerías A, Batchelder EM, Plongthongkum N, Lutz M, Berggren WT, Zhang K, Evans RM, Siuzdak G, Izpisua Belmonte JC. The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming. Cell Research. 22: 168-77. PMID 22064701 DOI: 10.1038/Cr.2011.177  1
2012 Ito K, Carracedo A, Arai F, Ala U, Avigan D, Schafer Z, Evans RM, Suda T, Lee C, Pandolfi PP. A PML–PPAR-δ Pathway for Fatty Acid Oxidation Regulates Hematopoietic Stem Cell Maintenance Through the Control of Asymmetric Division. Blood. 120: 2327-2327. DOI: 10.1182/Blood.V120.21.2327.2327  0.01
2012 Matsakas A, Yadav V, Lorca S, Evans RM, Narkar VA. Erratum: Revascularization of ischemic skeletal muscle by estrogen-related receptor-γ (Circulation Research (2012) 110 (1087-1096) DOI: 10.1161/CIRCRESAHA.112.266478) Circulation Research. 111. DOI: 10.1161/Res.0B013E31827806Cf  1
2012 Evans RM, Opher M, Oran R, Van Der Holst B, Sokolov IV, Frazin R, Gombosi TI, Vásquez A. Coronal heating by surface Alfvén wave damping: Implementation in a global magnetohydrodynamics model of the solar wind Astrophysical Journal. 756. DOI: 10.1088/0004-637X/756/2/155  1
2012 Uhlenhaut N, Barish G, Yu R, Downes M, Hübner N, Evans R. The GR at inflammatory crossroads Experimental and Clinical Endocrinology & Diabetes. 120. DOI: 10.1055/s-0032-1330829  0.01
2012 Jonker JW, Suh J, Atkins AR, Ahmadian M, Li P, Whyte J, He M, Juguilon H, Yin Y, Phillips CT, Yu RT, Olefsky JM, Henry RR, Downes M, Evans RM. PS21 - 100. A PPAR -FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis Nederlands Tijdschrift Voor Diabetologie. 10: 170-170. DOI: 10.1007/s12467-012-0134-8  0.01
2012 Martin OV, Evans RM. Naturally Occurring Oestrogens Pollutants, Human Health and the Environment: a Risk Based Approach. 229-254. DOI: 10.1002/9781119950127.ch9  1
2012 Evans RM, Ott MJ. Structureborne noise attenuation using strut-integrated isolators 41st International Congress and Exposition On Noise Control Engineering 2012, Inter-Noise 2012. 3: 2018-2028.  1
2011 Fan W, Downes M, Atkins A, Yu R, Evans RM. Nuclear receptors and AMPK: resetting metabolism. Cold Spring Harbor Symposia On Quantitative Biology. 76: 17-22. PMID 22411605 DOI: 10.1101/sqb.2012.76.010470  1
2011 Lamia KA, Papp SJ, Yu RT, Barish GD, Uhlenhaut NH, Jonker JW, Downes M, Evans RM. Cryptochromes mediate rhythmic repression of the glucocorticoid receptor. Nature. 480: 552-6. PMID 22170608 DOI: 10.1038/Nature10700  1
2011 Krebs P, Fan W, Chen YH, Tobita K, Downes MR, Wood MR, Sun L, Li X, Xia Y, Ding N, Spaeth JM, Moresco EM, Boyer TG, Lo CW, Yen J, ... Evans RM, et al. Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet. Proceedings of the National Academy of Sciences of the United States of America. 108: 19678-82. PMID 22106289 DOI: 10.1073/Pnas.1117835108  1
2011 Yamamoto H, Williams EG, Mouchiroud L, Cantó C, Fan W, Downes M, Héligon C, Barish GD, Desvergne B, Evans RM, Schoonjans K, Auwerx J. NCoR1 is a conserved physiological modulator of muscle mass and oxidative function. Cell. 147: 827-39. PMID 22078881 DOI: 10.1016/j.cell.2011.10.017  1
2011 Loveridge EJ, Tey LH, Behiry EM, Dawson WM, Evans RM, Whittaker SB, Günther UL, Williams C, Crump MP, Allemann RK. The role of large-scale motions in catalysis by dihydrofolate reductase. Journal of the American Chemical Society. 133: 20561-70. PMID 22060818 DOI: 10.1021/Ja208844J  1
2011 Pei L, Leblanc M, Barish G, Atkins A, Nofsinger R, Whyte J, Gold D, He M, Kawamura K, Li HR, Downes M, Yu RT, Powell HC, Lingrel JB, Evans RM. Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome. Nature Medicine. 17: 1466-72. PMID 22001906 DOI: 10.1038/Nm.2450  1
2011 Loveridge EJ, Dawson WM, Evans RM, Sobolewska A, Allemann RK. Reduced susceptibility of Moritella profunda dihydrofolate reductase to trimethoprim is not due to glutamate 28. The Protein Journal. 30: 546-8. PMID 21968646 DOI: 10.1007/S10930-011-9361-X  1
2011 Murphy SH, Suzuki K, Downes M, Welch GL, De Jesus P, Miraglia LJ, Orth AP, Chanda SK, Evans RM, Verma IM. Tumor suppressor protein (p)53, is a regulator of NF-kappaB repression by the glucocorticoid receptor. Proceedings of the National Academy of Sciences of the United States of America. 108: 17117-22. PMID 21949408 DOI: 10.1073/Pnas.1114420108  1
2011 Lukey MJ, Roessler MM, Parkin A, Evans RM, Davies RA, Lenz O, Friedrich B, Sargent F, Armstrong FA. Oxygen-tolerant [NiFe]-hydrogenases: the individual and collective importance of supernumerary cysteines at the proximal Fe-S cluster. Journal of the American Chemical Society. 133: 16881-92. PMID 21916508 DOI: 10.1021/Ja205393W  1
2011 Sugii S, Evans RM. Epigenetic codes of PPARγ in metabolic disease. Febs Letters. 585: 2121-8. PMID 21605560 DOI: 10.1016/J.Febslet.2011.05.007  1
2011 Mihaylova MM, Vasquez DS, Ravnskjaer K, Denechaud PD, Yu RT, Alvarez JG, Downes M, Evans RM, Montminy M, Shaw RJ. Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis. Cell. 145: 607-21. PMID 21565617 DOI: 10.1016/J.Cell.2011.03.043  1
2011 Kacevska M, Downes MR, Sharma R, Evans RM, Clarke SJ, Liddle C, Robertson GR. Extrahepatic cancer suppresses nuclear receptor-regulated drug metabolism. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3170-80. PMID 21498392 DOI: 10.1158/1078-0432.CCR-10-3289  1
2011 Sugii S, Kida Y, Berggren WT, Evans RM. Feeder-dependent and feeder-independent iPS cell derivation from human and mouse adipose stem cells. Nature Protocols. 6: 346-58. PMID 21372815 DOI: 10.1038/Nprot.2010.199  1
2011 Narkar VA, Fan W, Downes M, Yu RT, Jonker JW, Alaynick WA, Banayo E, Karunasiri MS, Lorca S, Evans RM. Exercise and PGC-1α-independent synchronization of type I muscle metabolism and vasculature by ERRγ. Cell Metabolism. 13: 283-93. PMID 21356518 DOI: 10.1016/J.Cmet.2011.01.019  1
2011 Fang S, Suh JM, Atkins AR, Hong SH, Leblanc M, Nofsinger RR, Yu RT, Downes M, Evans RM. Corepressor SMRT promotes oxidative phosphorylation in adipose tissue and protects against diet-induced obesity and insulin resistance. Proceedings of the National Academy of Sciences of the United States of America. 108: 3412-7. PMID 21300871 DOI: 10.1073/Pnas.1017707108  1
2011 Lister R, Pelizzola M, Kida YS, Hawkins RD, Nery JR, Hon G, Antosiewicz-Bourget J, O'Malley R, Castanon R, Klugman S, Downes M, Yu R, Stewart R, Ren B, Thomson JA, ... Evans RM, et al. Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature. 471: 68-73. PMID 21289626 DOI: 10.1038/Nature09798  1
2011 Diehl CJ, Barish GD, Downes M, Chou MY, Heinz S, Glass CK, Evans RM, Witztum JL. Research resource: Comparative nuclear receptor atlas: basal and activated peritoneal B-1 and B-2 cells. Molecular Endocrinology (Baltimore, Md.). 25: 529-45. PMID 21273443 DOI: 10.1210/Me.2010-0384  1
2011 Berry R, Harewood L, Pei L, Fisher M, Brownstein D, Ross A, Alaynick WA, Moss J, Hastie ND, Hohenstein P, Davies JA, Evans RM, FitzPatrick DR. Esrrg functions in early branch generation of the ureteric bud and is essential for normal development of the renal papilla. Human Molecular Genetics. 20: 917-26. PMID 21138943 DOI: 10.1093/Hmg/Ddq530  1
2011 Shimozaki K, Zhang C, Suh H, Denli A, Evans RM, Gage FH. Functional roles of Sox2 for the molecular regulation of TLX/NR2E1 in adult neural stem/progenitor cells Neuroscience Research. 71: e124. DOI: 10.1016/J.Neures.2011.07.531  0.01
2010 Reilly SM, Bhargava P, Liu S, Gangl MR, Gorgun C, Nofsinger RR, Evans RM, Qi L, Hu FB, Lee CH. Nuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deterioration. Cell Metabolism. 12: 643-53. PMID 21109196 DOI: 10.1016/J.Cmet.2010.11.007  1
2010 Barish GD, Yu RT, Karunasiri M, Ocampo CB, Dixon J, Benner C, Dent AL, Tangirala RK, Evans RM. Bcl-6 and NF-kappaB cistromes mediate opposing regulation of the innate immune response. Genes & Development. 24: 2760-5. PMID 21106671 DOI: 10.1101/Gad.1998010  1
2010 Szanto A, Balint BL, Nagy ZS, Barta E, Dezso B, Pap A, Szeles L, Poliska S, Oros M, Evans RM, Barak Y, Schwabe J, Nagy L. STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells. Immunity. 33: 699-712. PMID 21093321 DOI: 10.1016/J.Immuni.2010.11.009  1
2010 Evans RM, Davies M. ScoreCentre: a computer program to assist with collection and calculation of BBB locomotor scale data. Journal of Neuroscience Methods. 194: 102-7. PMID 20933007 DOI: 10.1016/j.jneumeth.2010.09.018  1
2010 Evans RM, Simha RA, Baule A, Olmsted PD. Statistical mechanics far from equilibrium: prediction and test for a sheared system. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 81: 051109. PMID 20866187 DOI: 10.1103/Physreve.81.051109  1
2010 Evans RM, Behiry EM, Tey LH, Guo J, Loveridge EJ, Allemann RK. Catalysis by dihydrofolate reductase from the psychropiezophile Moritella profunda. Chembiochem : a European Journal of Chemical Biology. 11: 2010-7. PMID 20726028 DOI: 10.1002/Cbic.201000341  1
2010 Lamia KA, Evans RM. Metabolism: Tick, tock, a beta-cell clock. Nature. 466: 571-2. PMID 20671699 DOI: 10.1038/466571A  1
2010 Wei W, Wang X, Yang M, Smith LC, Dechow PC, Sonoda J, Evans RM, Wan Y. PGC1beta mediates PPARgamma activation of osteoclastogenesis and rosiglitazone-induced bone loss. Cell Metabolism. 11: 503-16. PMID 20519122 DOI: 10.1016/J.Cmet.2010.04.015  0.08
2010 Shaw RJ, Evans RM, Simon MC. Metabolism and cancer in La Jolla. Cancer Research. 70: 3864-9. PMID 20442287 DOI: 10.1158/0008-5472.Can-09-4529  1
2010 Tassieri M, Gibson GM, Evans RM, Yao AM, Warren R, Padgett MJ, Cooper JM. Measuring storage and loss moduli using optical tweezers: broadband microrheology. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 81: 026308. PMID 20365652  1
2010 Sugii S, Kida Y, Kawamura T, Suzuki J, Vassena R, Yin YQ, Lutz MK, Berggren WT, Izpisúa Belmonte JC, Evans RM. Human and mouse adipose-derived cells support feeder-independent induction of pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 3558-63. PMID 20133714 DOI: 10.1073/Pnas.0910172106  1
2010 Helfand BT, Evans RM, McVary KT. A comparison of the frequencies of medical therapies for overactive bladder in men and women: analysis of more than 7.2 million aging patients. European Urology. 57: 586-91. PMID 20036783 DOI: 10.1016/J.Eururo.2009.12.025  1
2010 Evans RM, Rahte S, Kortenkamp A. Inability to confirm estrogenicity of the heterocyclic amine PhIP in two in vitro assays. Toxicology in Vitro : An International Journal Published in Association With Bibra. 24: 1757-63. PMID 20036730 DOI: 10.1016/j.tiv.2009.12.017  1
2010 Qu Q, Sun G, Li W, Yang S, Ye P, Zhao C, Yu RT, Gage FH, Evans RM, Shi Y. Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal. Nature Cell Biology. 12: 31-40; sup pp 1-9. PMID 20010817 DOI: 10.1038/ncb2001  1
2010 Alaynick WA, Way JM, Wilson SA, Benson WG, Pei L, Downes M, Yu R, Jonker JW, Holt JA, Rajpal DK, Li H, Stuart J, McPherson R, Remlinger KS, Chang CY, ... ... Evans RM, et al. ERRgamma regulates cardiac, gastric, and renal potassium homeostasis. Molecular Endocrinology (Baltimore, Md.). 24: 299-309. PMID 19965931 DOI: 10.1210/Me.2009-0114  1
2010 Evans RM, You H, Hameed S, Altier C, Mezghrani A, Bourinet E, Zamponi GW. Heterodimerization of ORL1 and opioid receptors and its consequences for N-type calcium channel regulation. The Journal of Biological Chemistry. 285: 1032-40. PMID 19887453 DOI: 10.1074/Jbc.M109.040634  1
2010 Wan Y, Evans RM. Rosiglitazone activation of PPARgamma suppresses fractalkine signaling. Journal of Molecular Endocrinology. 44: 135-42. PMID 19850645 DOI: 10.1677/Jme-09-0090  1
2010 Jiang YJ, Barish G, Lu B, Evans RM, Crumrine D, Schmuth M, Elias PM, Feingold KR. PPARδ activation promotes stratum corneum formation and epidermal permeability barrier development during late gestation. The Journal of Investigative Dermatology. 130: 511-9. PMID 19675577 DOI: 10.1038/jid.2009.245  1
2010 Evans RM, Harridge SD, Velloso CP, Yang SY, Goldspink G, Orrell RW. Investigation of MGF mRNA expression in patients with amyotrophic lateral sclerosis using parallel in vivo and in vitro approaches. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 11: 172-7. PMID 19572220 DOI: 10.3109/17482960903089775  0.04
2010 Gearhart M, Holmbeck S, Evans R, Dyson H, Wright P. 1H, 13C, and 15N Chemical shifts for hERR2 Protein, 1H chemical shifts for DNA Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr5363  0.01
2010 Sternsdorf T, Ocampo-Bayuga C, Haschke A, Dierk K, Prall S, Horstmann M, Evans R. Positive evidence for a role of the PML pathway in leukemogenesis of acute promyelocytic leukemia Klinische PäDiatrie. 222. DOI: 10.1055/S-0030-1254462  0.01
2010 Wei W, Wang X, Yang M, Smith LC, Dechow PC, Sonoda J, Evans RM, Wan Y. PGC1β Mediates PPARγ Activation of Osteoclastogenesis and Rosiglitazone-Induced Bone Loss Cell Metabolism. 12: 202. DOI: 10.1016/J.Cmet.2010.07.007  0.01
2009 Alaynick WA, Way JM, Wilson SA, Benson WG, Pei L, Downes M, Yu R, Jonker JW, Holt JA, Rajpal DK, Li H, Stuart J, McPherson R, Remlinger KS, Yi-Chang C, ... ... Evans RM, et al. ERRγ Regulates Cardiac, Gastric, and Renal Potassium Homeostasis. Endocrine Reviews. 30: 931. PMID 28199598 DOI: 10.1210/Edrv.30.7.9988  1
2009 Evans RM. Nuclear receptors: past, present, and future. Preface. Progress in Molecular Biology and Translational Science. 87: xi-xiii. PMID 20374698 DOI: 10.1016/S1877-1173(09)87015-4  1
2009 Sugii S, Olson P, Sears DD, Saberi M, Atkins AR, Barish GD, Hong SH, Castro GL, Yin YQ, Nelson MC, Hsiao G, Greaves DR, Downes M, Yu RT, Olefsky JM, ... Evans RM, et al. PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization. Proceedings of the National Academy of Sciences of the United States of America. 106: 22504-9. PMID 20018750 DOI: 10.1073/Pnas.0912487106  1
2009 Lamia KA, Sachdeva UM, DiTacchio L, Williams EC, Alvarez JG, Egan DF, Vasquez DS, Juguilon H, Panda S, Shaw RJ, Thompson CB, Evans RM. AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation. Science (New York, N.Y.). 326: 437-40. PMID 19833968 DOI: 10.1126/Science.1172156  1
2009 Hay S, Evans RM, Levy C, Loveridge EJ, Wang X, Leys D, Allemann RK, Scrutton NS. Are the catalytic properties of enzymes from piezophilic organisms pressure adapted? Chembiochem : a European Journal of Chemical Biology. 10: 2348-53. PMID 19681091 DOI: 10.1002/Cbic.200900367  1
2009 Evans RM, Tassieri M, Auhl D, Waigh TA. Direct conversion of rheological compliance measurements into storage and loss moduli. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 80: 012501. PMID 19658751  1
2009 Pei L, Evans RM. Retrofitting fat metabolism. Cell Metabolism. 9: 483-4. PMID 19490901 DOI: 10.1016/J.Cmet.2009.05.006  1
2009 McKenna NJ, Cooney AJ, DeMayo FJ, Downes M, Glass CK, Lanz RB, Lazar MA, Mangelsdorf DJ, Moore DD, Qin J, Steffen DL, Tsai MJ, Tsai SY, Yu R, Margolis RN, ... Evans RM, et al. Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Molecular Endocrinology (Baltimore, Md.). 23: 740-6. PMID 19423650 DOI: 10.1210/Me.2009-0135  1
2009 Allemann RK, Evans RM, Loveridge EJ. Probing coupled motions in enzymatic hydrogen tunnelling reactions. Biochemical Society Transactions. 37: 349-53. PMID 19290860 DOI: 10.1042/Bst0370349  1
2009 Evans RM. Physician prescribing information adds context to AMA CME program. The West Virginia Medical Journal. 105: 44-5. PMID 19146047  0.01
2008 Baule A, Evans RM. Invariant quantities in shear flow. Physical Review Letters. 101: 240601. PMID 19113609  1
2008 Tassieri M, Evans RM, Barbu-Tudoran L, Khaname GN, Trinick J, Waigh TA. Dynamics of semiflexible polymer solutions in the highly entangled regime. Physical Review Letters. 101: 198301. PMID 19113316 DOI: 10.1103/Physrevlett.101.198301  1
2008 Nofsinger RR, Li P, Hong SH, Jonker JW, Barish GD, Ying H, Cheng SY, Leblanc M, Xu W, Pei L, Kang YJ, Nelson M, Downes M, Yu RT, Olefsky JM, ... ... Evans RM, et al. SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 105: 20021-6. PMID 19066220 DOI: 10.1073/Pnas.0811012105  1
2008 Vold SD, Evans RM, Stewart RH, Walters T, Mallick S. A one-week comfort study of BID-dosed brinzolamide 1%/timolol 0.5% ophthalmic suspension fixed combination compared to BID-dosed dorzolamide 2%/timolol 0.5% ophthalmic solution in patients with open-angle glaucoma or ocular hypertension. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 24: 601-5. PMID 19049301 DOI: 10.1089/jop.2008.0030  0.01
2008 Loveridge EJ, Evans RM, Allemann RK. Solvent effects on environmentally coupled hydrogen tunnelling during catalysis by dihydrofolate reductase from Thermotoga maritima. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 10782-8. PMID 18924193 DOI: 10.1002/Chem.200801804  1
2008 Davies BS, Waki H, Beigneux AP, Farber E, Weinstein MM, Wilpitz DC, Tai LJ, Evans RM, Fong LG, Tontonoz P, Young SG. The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma. Molecular Endocrinology (Baltimore, Md.). 22: 2496-504. PMID 18787041 DOI: 10.1210/Me.2008-0146  1
2008 Kleiner HE, Xia X, Sonoda J, Zhang J, Pontius E, Abey J, Evans RM, Moore DD, DiGiovanni J. Effects of naturally occurring coumarins on hepatic drug-metabolizing enzymes in mice. Toxicology and Applied Pharmacology. 232: 337-50. PMID 18692084 DOI: 10.1016/J.Taap.2008.07.004  1
2008 Narkar VA, Downes M, Yu RT, Embler E, Wang YX, Banayo E, Mihaylova MM, Nelson MC, Zou Y, Juguilon H, Kang H, Shaw RJ, Evans RM. AMPK and PPARdelta agonists are exercise mimetics. Cell. 134: 405-15. PMID 18674809 DOI: 10.1016/J.Cell.2008.06.051  1
2008 Tillin T, Evans RM, Witt NW, Sharp PS, McKeigue PM, Chaturvedi N, Hughes AD. Ethnic differences in retinal microvascular structure. Diabetologia. 51: 1719-22. PMID 18626625 DOI: 10.1007/s00125-008-1096-7  0.01
2008 Hay S, Pang J, Monaghan PJ, Wang X, Evans RM, Sutcliffe MJ, Allemann RK, Scrutton NS. Secondary kinetic isotope effects as probes of environmentally-coupled enzymatic hydrogen tunneling reactions. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 9: 1536-9. PMID 18613201 DOI: 10.1002/Cphc.200800291  1
2008 Shipe WD, Barrow JC, Yang ZQ, Lindsley CW, Yang FV, Schlegel KA, Shu Y, Rittle KE, Bock MG, Hartman GD, Tang C, Ballard JE, Kuo Y, Adarayan ED, Prueksaritanont T, ... ... Evans RM, et al. Design, synthesis, and evaluation of a novel 4-aminomethyl-4-fluoropiperidine as a T-type Ca2+ channel antagonist. Journal of Medicinal Chemistry. 51: 3692-5. PMID 18540666 DOI: 10.1021/Jm800419W  1
2008 Simha A, Evans RM, Baule A. Properties of a nonequilibrium heat bath. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 77: 031117. PMID 18517339  1
2008 Evans RM, Wease KN, MacDonald CJ, Khairy HA, Ross RA, Scott RH. Modulation of sensory neuron potassium conductances by anandamide indicates roles for metabolites. British Journal of Pharmacology. 154: 480-92. PMID 18376419 DOI: 10.1038/bjp.2008.93  1
2008 Barish GD, Atkins AR, Downes M, Olson P, Chong LW, Nelson M, Zou Y, Hwang H, Kang H, Curtiss L, Evans RM, Lee CH. PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 4271-6. PMID 18337509 DOI: 10.1073/Pnas.0711875105  1
2008 Takata Y, Liu J, Yin F, Collins AR, Lyon CJ, Lee CH, Atkins AR, Downes M, Barish GD, Evans RM, Hsueh WA, Tangirala RK. PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 4277-82. PMID 18337495 DOI: 10.1073/pnas.0708647105  1
2008 Downes M, Evans RM. Staying the distance: avoiding the proteasomal trap. Cancer Cell. 13: 184-5. PMID 18328421 DOI: 10.1016/j.ccr.2008.02.014  1
2008 Yang X, Ongusaha PP, Miles PD, Havstad JC, Zhang F, So WV, Kudlow JE, Michell RH, Olefsky JM, Field SJ, Evans RM. Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance. Nature. 451: 964-9. PMID 18288188 DOI: 10.1038/Nature06668  1
2008 Zhang CL, Zou Y, He W, Gage FH, Evans RM. A role for adult TLX-positive neural stem cells in learning and behaviour. Nature. 451: 1004-7. PMID 18235445 DOI: 10.1038/nature06562  1
2008 Tassieri M, Evans RM, Barbu-Tudoran L, Trinick J, Waigh TA. The self-assembly, elasticity, and dynamics of cardiac thin filaments. Biophysical Journal. 94: 2170-8. PMID 18065478 DOI: 10.1529/Biophysj.107.116087  1
2008 Yang CS, Ko SR, Cho BG, Shin DM, Yuk JM, Li S, Kim JM, Evans RM, Jung JS, Song DK, Jo EK. The ginsenoside metabolite compound K, a novel agonist of glucocorticoid receptor, induces tolerance to endotoxin-induced lethal shock. Journal of Cellular and Molecular Medicine. 12: 1739-53. PMID 18053081 DOI: 10.1111/j.1582-4934.2007.00181.x  1
2008 Sonoda J, Pei L, Evans RM. Nuclear receptors: decoding metabolic disease. Febs Letters. 582: 2-9. PMID 18023286 DOI: 10.1016/J.Febslet.2007.11.016  1
2008 Man MQ, Barish GD, Schmuth M, Crumrine D, Barak Y, Chang S, Jiang Y, Evans RM, Elias PM, Feingold KR. Deficiency of PPARbeta/delta in the epidermis results in defective cutaneous permeability barrier homeostasis and increased inflammation. The Journal of Investigative Dermatology. 128: 370-7. PMID 17713572 DOI: 10.1038/sj.jid.5701026  1
2008 Narkar VA, Downes M, Yu RT, Embler E, Wang YX, Banayo E, Mihaylova MM, Nelson MC, Zou Y, Juguilon H, Kang H, Shaw RJ, Evans RM. AMPK and PPARδ Agonists Are Exercise Mimetics (DOI:10.1016/j.cell.2008.06.051) Cell. 135: 189. DOI: 10.1016/J.Cell.2008.09.014  1
2008 Li T, Sonoda J, Evans RM. Establishing Orphan Nuclear Receptors PXR and CAR as Xenobiotic Receptors Nuclear Receptors in Drug Metabolism. 43-59. DOI: 10.1002/9780470409107.ch2  1
2007 Yang X, Lamia KA, Evans RM. Nuclear receptors, metabolism, and the circadian clock. Cold Spring Harbor Symposia On Quantitative Biology. 72: 387-94. PMID 18419296 DOI: 10.1101/Sqb.2007.72.058  1
2007 Wan Y, Chong LW, Evans RM. PPAR-gamma regulates osteoclastogenesis in mice. Nature Medicine. 13: 1496-503. PMID 18059282 DOI: 10.1038/Nm1672  1
2007 Santilman V, Baran J, Anand-Apte B, Evans RM, Parat MO. Caveolin-1 polarization in transmigrating endothelial cells requires binding to intermediate filaments. Angiogenesis. 10: 297-305. PMID 17955336 DOI: 10.1007/s10456-007-9083-z  0.01
2007 Sun G, Yu RT, Evans RM, Shi Y. Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 104: 15282-7. PMID 17873065 DOI: 10.1073/pnas.0704089104  1
2007 Evans RM, Scott RH, Ross RA. Chronic exposure of sensory neurones to increased levels of nerve growth factor modulates CB1/TRPV1 receptor crosstalk. British Journal of Pharmacology. 152: 404-13. PMID 17700720 DOI: 10.1038/sj.bjp.0707411  1
2007 Ding G, Fu M, Qin Q, Lewis W, Kim HW, Fukai T, Bacanamwo M, Chen YE, Schneider MD, Mangelsdorf DJ, Evans RM, Yang Q. Cardiac peroxisome proliferator-activated receptor gamma is essential in protecting cardiomyocytes from oxidative damage. Cardiovascular Research. 76: 269-79. PMID 17678635 DOI: 10.1016/j.cardiores.2007.06.027  1
2007 Sonoda J, Laganière J, Mehl IR, Barish GD, Chong LW, Li X, Scheffler IE, Mock DC, Bataille AR, Robert F, Lee CH, Giguère V, Evans RM. Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense. Genes & Development. 21: 1909-20. PMID 17671090 DOI: 10.1101/Gad.1553007  1
2007 Wan Y, Saghatelian A, Chong LW, Zhang CL, Cravatt BF, Evans RM. Maternal PPAR gamma protects nursing neonates by suppressing the production of inflammatory milk. Genes & Development. 21: 1895-908. PMID 17652179 DOI: 10.1101/Gad.1567207  1
2007 Alaynick WA, Kondo RP, Xie W, He W, Dufour CR, Downes M, Jonker JW, Giles W, Naviaux RK, Giguère V, Evans RM. ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart. Cell Metabolism. 6: 13-24. PMID 17618853 DOI: 10.1016/J.Cmet.2007.06.007  1
2007 Bargagna-Mohan P, Hamza A, Kim YE, Khuan Abby Ho Y, Mor-Vaknin N, Wendschlag N, Liu J, Evans RM, Markovitz DM, Zhan CG, Kim KB, Mohan R. The tumor inhibitor and antiangiogenic agent withaferin A targets the intermediate filament protein vimentin. Chemistry & Biology. 14: 623-34. PMID 17584610 DOI: 10.1016/J.Chembiol.2007.04.010  1
2007 Altier C, Dale CS, Kisilevsky AE, Chapman K, Castiglioni AJ, Matthews EA, Evans RM, Dickenson AH, Lipscombe D, Vergnolle N, Zamponi GW. Differential role of N-type calcium channel splice isoforms in pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6363-73. PMID 17567797 DOI: 10.1523/Jneurosci.0307-07.2007  1
2007 Dufour CR, Wilson BJ, Huss JM, Kelly DP, Alaynick WA, Downes M, Evans RM, Blanchette M, Giguère V. Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma. Cell Metabolism. 5: 345-56. PMID 17488637 DOI: 10.1016/J.Cmet.2007.03.007  1
2007 Sonoda J, Mehl IR, Chong LW, Nofsinger RR, Evans RM. PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis. Proceedings of the National Academy of Sciences of the United States of America. 104: 5223-8. PMID 17360356 DOI: 10.1073/Pnas.0611623104  1
2007 Buchanan M, Molenaar D, Villiers Sd, Evans RM. Pattern formation in draining thin film suspensions. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 3732-6. PMID 17316037 DOI: 10.1021/la063282a  0.01
2007 Yoh SM, Cho H, Pickle L, Evans RM, Jones KA. The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export. Genes & Development. 21: 160-74. PMID 17234882 DOI: 10.1101/Gad.1503107  1
2006 Baule A, Evans RM, Olmsted PD. Validation of the Jarzynski relation for a system with strong thermal coupling: an isothermal ideal gas model. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 74: 061117. PMID 17280048 DOI: 10.1103/Physreve.74.061117  1
2006 Germain P, Chambon P, Eichele G, Evans RM, Lazar MA, Leid M, De Lera AR, Lotan R, Mangelsdorf DJ, Gronemeyer H. International Union of Pharmacology. LXIII. Retinoid X receptors. Pharmacological Reviews. 58: 760-72. PMID 17132853 DOI: 10.1124/Pr.58.4.7  1
2006 Germain P, Chambon P, Eichele G, Evans RM, Lazar MA, Leid M, De Lera AR, Lotan R, Mangelsdorf DJ, Gronemeyer H. International Union of Pharmacology. LX. Retinoic acid receptors. Pharmacological Reviews. 58: 712-25. PMID 17132850 DOI: 10.1124/Pr.58.4.4  1
2006 Evans RM, Zamponi GW. Presynaptic Ca2+ channels--integration centers for neuronal signaling pathways. Trends in Neurosciences. 29: 617-24. PMID 16942804 DOI: 10.1016/J.Tins.2006.08.006  1
2006 Yang X, Downes M, Yu RT, Bookout AL, He W, Straume M, Mangelsdorf DJ, Evans RM. Nuclear receptor expression links the circadian clock to metabolism. Cell. 126: 801-10. PMID 16923398 DOI: 10.1016/J.Cell.2006.06.050  1
2006 Bookout AL, Jeong Y, Downes M, Yu RT, Evans RM, Mangelsdorf DJ. Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell. 126: 789-99. PMID 16923397 DOI: 10.1016/j.cell.2006.06.049  1
2006 Kharroubi I, Lee CH, Hekerman P, Darville MI, Evans RM, Eizirik DL, Cnop M. BCL-6: a possible missing link for anti-inflammatory PPAR-delta signalling in pancreatic beta cells. Diabetologia. 49: 2350-8. PMID 16896941 DOI: 10.1007/s00125-006-0366-5  1
2006 Allemann RK, Evans RM, Tey LH, Maglia G, Pang J, Rodriguez R, Shrimpton PJ, Swanwick RS. Protein motions during catalysis by dihydrofolate reductases. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 361: 1317-21. PMID 16873119 DOI: 10.1098/Rstb.2006.1865  1
2006 Stedman C, Liddle C, Coulter S, Sonoda J, Alvarez JG, Evans RM, Downes M. Benefit of farnesoid X receptor inhibition in obstructive cholestasis. Proceedings of the National Academy of Sciences of the United States of America. 103: 11323-8. PMID 16844773 DOI: 10.1073/Pnas.0604772103  1
2006 Qi L, Heredia JE, Altarejos JY, Screaton R, Goebel N, Niessen S, Macleod IX, Liew CW, Kulkarni RN, Bain J, Newgard C, Nelson M, Evans RM, Yates J, Montminy M. TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. Science (New York, N.Y.). 312: 1763-6. PMID 16794074 DOI: 10.1126/Science.1123374  1
2006 Zhang CL, Zou Y, Yu RT, Gage FH, Evans RM. Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes & Development. 20: 1308-20. PMID 16702404 DOI: 10.1101/gad.1413606  1
2006 Zhou J, Zhai Y, Mu Y, Gong H, Uppal H, Toma D, Ren S, Evans RM, Xie W. A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway. The Journal of Biological Chemistry. 281: 15013-20. PMID 16556603 DOI: 10.1074/jbc.M511116200  1
2006 Barish GD, Narkar VA, Evans RM. PPAR delta: a dagger in the heart of the metabolic syndrome. The Journal of Clinical Investigation. 116: 590-7. PMID 16511591 DOI: 10.1172/JCI27955  1
2006 Jacobs S, Lie DC, DeCicco KL, Shi Y, DeLuca LM, Gage FH, Evans RM. Retinoic acid is required early during adult neurogenesis in the dentate gyrus. Proceedings of the National Academy of Sciences of the United States of America. 103: 3902-7. PMID 16505366 DOI: 10.1073/pnas.0511294103  1
2006 Lee CH, Olson P, Hevener A, Mehl I, Chong LW, Olefsky JM, Gonzalez FJ, Ham J, Kang H, Peters JM, Evans RM. PPARdelta regulates glucose metabolism and insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 103: 3444-9. PMID 16492734 DOI: 10.1073/Pnas.0511253103  1
2006 Sternsdorf T, Phan VT, Maunakea ML, Ocampo CB, Sohal J, Silletto A, Galimi F, Le Beau MM, Evans RM, Kogan SC. Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia. Cancer Cell. 9: 81-94. PMID 16473276 DOI: 10.1016/J.Ccr.2005.12.030  1
2006 Lee CH, Kang K, Mehl IR, Nofsinger R, Alaynick WA, Chong LW, Rosenfeld JM, Evans RM. Peroxisome proliferator-activated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage. Proceedings of the National Academy of Sciences of the United States of America. 103: 2434-9. PMID 16467150 DOI: 10.1073/Pnas.0510815103  1
2006 Wang Z, Qi C, Krones A, Woodring P, Zhu X, Reddy JK, Evans RM, Rosenfeld MG, Hunter T. Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance. Cell Metabolism. 3: 111-22. PMID 16459312 DOI: 10.1016/J.Cmet.2006.01.002  1
2006 Altier C, Khosravani H, Evans RM, Hameed S, Peloquin JB, Vartian BA, Chen L, Beedle AM, Ferguson SS, Mezghrani A, Dubel SJ, Bourinet E, McRory JE, Zamponi GW. ORL1 receptor-mediated internalization of N-type calcium channels. Nature Neuroscience. 9: 31-40. PMID 16311589 DOI: 10.1038/Nn1605  1
2006 Gureje O, Ogunniyi A, Baiyewu O, Price B, Unverzagt FW, Evans RM, Smith-Gamble V, Lane KA, Gao S, Hall KS, Hendrie HC, Murrell JR. APOE epsilon4 is not associated with Alzheimer's disease in elderly Nigerians. Annals of Neurology. 59: 182-5. PMID 16278853 DOI: 10.1002/Ana.20694  1
2006 Ho MW, Dhariwal DK, Chandrasekhar J, Patton DW, Silvester KC, Sadiq S, Evans RM. Use of interventional radiology in the management of mediastinitis of odontogenic origin. The British Journal of Oral & Maxillofacial Surgery. 44: 538-42. PMID 16233941 DOI: 10.1016/j.bjoms.2005.09.003  1
2005 Li Z, Chen W, Hale JJ, Lynch CL, Mills SG, Hajdu R, Keohane CA, Rosenbach MJ, Milligan JA, Shei GJ, Chrebet G, Parent SA, Bergstrom J, Card D, Forrest M, ... ... Evans RM, et al. Discovery of potent 3,5-diphenyl-1,2,4-oxadiazole sphingosine-1-phosphate-1 (S1P1) receptor agonists with exceptional selectivity against S1P2 and S1P3. Journal of Medicinal Chemistry. 48: 6169-73. PMID 16190743 DOI: 10.1021/jm0503244  1
2005 Zhao X, Sternsdorf T, Bolger TA, Evans RM, Yao TP. Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications. Molecular and Cellular Biology. 25: 8456-64. PMID 16166628 DOI: 10.1128/Mcb.25.19.8456-8464.2005  1
2005 Wolf KK, Wood SG, Hunt JA, Walton-Strong BW, Yasuda K, Lan L, Duan SX, Hao Q, Wrighton SA, Jeffery EH, Evans RM, Szakacs JG, von Moltke LL, Greenblatt DJ, Court MH, et al. Role of the nuclear receptor pregnane X receptor in acetaminophen hepatotoxicity. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 1827-36. PMID 16141365 DOI: 10.1124/dmd.105.005256  1
2005 Margolis RN, Evans RM, O'Malley BW. The Nuclear Receptor Signaling Atlas: development of a functional atlas of nuclear receptors. Molecular Endocrinology (Baltimore, Md.). 19: 2433-6. PMID 16051673 DOI: 10.1210/me.2004-0461  1
2005 Barish GD, Downes M, Alaynick WA, Yu RT, Ocampo CB, Bookout AL, Mangelsdorf DJ, Evans RM. A Nuclear Receptor Atlas: macrophage activation. Molecular Endocrinology (Baltimore, Md.). 19: 2466-77. PMID 16051664 DOI: 10.1210/Me.2004-0529  1
2005 Fu M, Sun T, Bookout AL, Downes M, Yu RT, Evans RM, Mangelsdorf DJ. A Nuclear Receptor Atlas: 3T3-L1 adipogenesis. Molecular Endocrinology (Baltimore, Md.). 19: 2437-50. PMID 16051663 DOI: 10.1210/me.2004-0539  1
2005 Evans RM. The nuclear receptor superfamily: a rosetta stone for physiology. Molecular Endocrinology (Baltimore, Md.). 19: 1429-38. PMID 15914712 DOI: 10.1210/me.2005-0046  0.01
2005 Noreault TL, Jacobs JM, Nichols RC, Trask HW, Wrighton SA, Sinclair PR, Evans RM, Sinclair JF. Arsenite decreases CYP3A23 induction in cultured rat hepatocytes by transcriptional and translational mechanisms. Toxicology and Applied Pharmacology. 209: 174-82. PMID 15907335 DOI: 10.1016/j.taap.2005.04.008  1
2005 Carrick L, Tassieri M, Waigh TA, Aggeli A, Boden N, Bell C, Fisher J, Ingham E, Evans RM. The internal dynamic modes of charged self-assembled peptide fibrils. Langmuir : the Acs Journal of Surfaces and Colloids. 21: 3733-7. PMID 15835929 DOI: 10.1021/La046802F  1
2005 Noreault TL, Kostrubsky VE, Wood SG, Nichols RC, Strom SC, Trask HW, Wrighton SA, Evans RM, Jacobs JM, Sinclair PR, Sinclair JF. Arsenite decreases CYP3A4 and RXRalpha in primary human hepatocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 993-1003. PMID 15833926 DOI: 10.1124/dmd.105.003954  1
2005 Pavri R, Lewis B, Kim TK, Dilworth FJ, Erdjument-Bromage H, Tempst P, de Murcia G, Evans R, Chambon P, Reinberg D. PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator. Molecular Cell. 18: 83-96. PMID 15808511 DOI: 10.1016/J.Molcel.2005.02.034  1
2005 Stedman CA, Liddle C, Coulter SA, Sonoda J, Alvarez JG, Moore DD, Evans RM, Downes M. Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury. Proceedings of the National Academy of Sciences of the United States of America. 102: 2063-8. PMID 15684063 DOI: 10.1073/Pnas.0409794102  1
2005 Sonoda J, Chong LW, Downes M, Barish GD, Coulter S, Liddle C, Lee CH, Evans RM. Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites. Proceedings of the National Academy of Sciences of the United States of America. 102: 2198-203. PMID 15671183 DOI: 10.1073/Pnas.0409481102  1
2005 Galimi F, Saez E, Gall J, Hoong N, Cho G, Evans RM, Verma IM. Development of ecdysone-regulated lentiviral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 142-8. PMID 15585415 DOI: 10.1016/J.Ymthe.2004.08.021  1
2005 Bechtold DA, Yue X, Evans RM, Davies M, Gregson NA, Smith KJ. Axonal protection in experimental autoimmune neuritis by the sodium channel blocking agent flecainide. Brain : a Journal of Neurology. 128: 18-28. PMID 15509620 DOI: 10.1093/Brain/Awh328  1
2004 Shalom-Barak T, Nicholas JM, Wang Y, Zhang X, Ong ES, Young TH, Gendler SJ, Evans RM, Barak Y. Peroxisome proliferator-activated receptor gamma controls Muc1 transcription in trophoblasts. Molecular and Cellular Biology. 24: 10661-9. PMID 15572671 DOI: 10.1128/MCB.24.24.10661-10669.2004  1
2004 Barish GD, Evans RM. A nuclear strike against Listeria--the evolving life of LXR. Cell. 119: 149-51. PMID 15479632 DOI: 10.1016/j.cell.2004.10.003  1
2004 Cheng L, Ding G, Qin Q, Huang Y, Lewis W, He N, Evans RM, Schneider MD, Brako FA, Xiao Y, Chen YE, Yang Q. Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy. Nature Medicine. 10: 1245-50. PMID 15475963 DOI: 10.1038/nm1116  1
2004 Evans R. A transcriptional basis for physiology. Nature Medicine. 10: 1022-1026. PMID 15459694 DOI: 10.1038/Nm1004-1022  0.01
2004 Zhang J, Huang W, Qatanani M, Evans RM, Moore DD. The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity. The Journal of Biological Chemistry. 279: 49517-22. PMID 15358766 DOI: 10.1074/Jbc.M409041200  1
2004 Wang YX, Zhang CL, Yu RT, Cho HK, Nelson MC, Bayuga-Ocampo CR, Ham J, Kang H, Evans RM. Regulation of muscle fiber type and running endurance by PPARdelta. Plos Biology. 2: e294. PMID 15328533 DOI: 10.1371/journal.pbio.0020294  1
2004 McClelland D, Evans RM, Barkworth L, Martin DJ, Scott RH. A study comparing the actions of gabapentin and pregabalin on the electrophysiological properties of cultured DRG neurones from neonatal rats. Bmc Pharmacology. 4: 14. PMID 15294026 DOI: 10.1186/1471-2210-4-14  1
2004 Evans RM. 2003 Keio Medical Science Prize commemorative lecture. PPARs and the complex journey to obesity. The Keio Journal of Medicine. 53: 53-8. PMID 15264367 DOI: 10.2302/Kjm.53.53  0.01
2004 Evans RM. Rules for transition rates in nonequilibrium steady states. Physical Review Letters. 92: 150601. PMID 15169275  0.01
2004 Evans RM, Hui S, Perkins A, Lahiri DK, Poirier J, Farlow MR. Cholesterol and APOE genotype interact to influence Alzheimer disease progression. Neurology. 62: 1869-71. PMID 15159498 DOI: 10.1212/01.Wnl.0000125323.15458.3F  1
2004 Barish GD, Evans RM. PPARs and LXRs: atherosclerosis goes nuclear. Trends in Endocrinology and Metabolism: Tem. 15: 158-65. PMID 15109614 DOI: 10.1016/j.tem.2004.03.003  1
2004 Koo SH, Satoh H, Herzig S, Lee CH, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M. PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nature Medicine. 10: 530-4. PMID 15107844 DOI: 10.1038/Nm1044  1
2004 Evans RM, Barish GD, Wang YX. PPARs and the complex journey to obesity. Nature Medicine. 10: 355-61. PMID 15057233 DOI: 10.1038/nm1025  1
2004 Saez E, Rosenfeld J, Livolsi A, Olson P, Lombardo E, Nelson M, Banayo E, Cardiff RD, Izpisua-Belmonte JC, Evans RM. PPAR gamma signaling exacerbates mammary gland tumor development. Genes & Development. 18: 528-40. PMID 15037548 DOI: 10.1101/Gad.1167804  1
2004 Evans RM, Scott RH, Ross RA. Multiple actions of anandamide on neonatal rat cultured sensory neurones. British Journal of Pharmacology. 141: 1223-33. PMID 15023857 DOI: 10.1038/sj.bjp.0705723  1
2004 Tsai CC, Kao HY, Mitzutani A, Banayo E, Rajan H, McKeown M, Evans RM. Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors. Proceedings of the National Academy of Sciences of the United States of America. 101: 4047-52. PMID 15016912 DOI: 10.1073/pnas.0400615101  1
2004 Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD. Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. The Journal of Biological Chemistry. 279: 22250-7. PMID 15004017 DOI: 10.1074/Jbc.M314111200  1
2004 Saini SP, Sonoda J, Xu L, Toma D, Uppal H, Mu Y, Ren S, Moore DD, Evans RM, Xie W. A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification. Molecular Pharmacology. 65: 292-300. PMID 14742670 DOI: 10.1124/Mol.65.2.292  1
2004 Xu W, Cho H, Kadam S, Banayo EM, Anderson S, Yates JR, Emerson BM, Evans RM. A methylation-mediator complex in hormone signaling. Genes & Development. 18: 144-56. PMID 14729568 DOI: 10.1101/Gad.1141704  1
2004 Shi Y, Chichung Lie D, Taupin P, Nakashima K, Ray J, Yu RT, Gage FH, Evans RM. Expression and function of orphan nuclear receptor TLX in adult neural stem cells. Nature. 427: 78-83. PMID 14702088 DOI: 10.1038/nature02211  1
2004 Demarest SJ, Deechongkit S, Dyson HJ, Evans RM, Wright PE. Packing, specificity, and mutability at the binding interface between the p160 coactivator and CREB-binding protein. Protein Science : a Publication of the Protein Society. 13: 203-10. PMID 14691235 DOI: 10.1110/Ps.03366504  1
2004 Kogan SC, Phan VT, Sternsdorf T, Maunakea ML, Sohal J, Silletto A, Galimi F, Evans RM. Homodimerization of Retinoic Acid Receptor alpha through its Fusion Partners Underlies Pathogenesis of Acute Promyelocytic Leukemia. Blood. 104: 546-546. DOI: 10.1182/Blood.V104.11.546.546  1
2004 Koo S, Satoh H, Herzig S, Lee C, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M. Erratum: PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3 Nature Medicine. 10: 755-755. DOI: 10.1038/Nm0704-755A  0.01
2003 Evans RM. An interview with Ronald M. Evans, Ph.D. Investigator, the Salk Institute for Biological Studies. Assay and Drug Development Technologies. 1: 749-54. PMID 15090221 DOI: 10.1089/154065803772613381  0.01
2003 Stahl DC, Evans RM, Afrin LB, DeTeresa RM, Ko D, Mitchell K. Web services-based access to local clinical trial databases: a standards initiative of the Association of American Cancer Institutes. Amia ... Annual Symposium Proceedings / Amia Symposium. Amia Symposium. 624-8. PMID 14728248  0.01
2003 He W, Barak Y, Hevener A, Olson P, Liao D, Le J, Nelson M, Ong E, Olefsky JM, Evans RM. Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle. Proceedings of the National Academy of Sciences of the United States of America. 100: 15712-7. PMID 14660788 DOI: 10.1073/Pnas.2536828100  1
2003 Natarajan C, Muthian G, Barak Y, Evans RM, Bright JJ. Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 171: 5743-50. PMID 14634082 DOI: 10.4049/Jimmunol.171.11.5743  1
2003 Xu W, Cho H, Evans RM. Acetylation and methylation in nuclear receptor gene activation. Methods in Enzymology. 364: 205-23. PMID 14631847 DOI: 10.1016/S0076-6879(03)64012-7  1
2003 Hevener AL, He W, Barak Y, Le J, Bandyopadhyay G, Olson P, Wilkes J, Evans RM, Olefsky J. Muscle-specific Pparg deletion causes insulin resistance. Nature Medicine. 9: 1491-7. PMID 14625542 DOI: 10.1038/Nm956  1
2003 Lee CH, Chawla A, Urbiztondo N, Liao D, Boisvert WA, Evans RM, Curtiss LK. Transcriptional repression of atherogenic inflammation: modulation by PPARdelta. Science (New York, N.Y.). 302: 453-7. PMID 12970571 DOI: 10.1126/science.1087344  1
2003 Saez E, Olson P, Evans RM. Genetic deficiency in Pparg does not alter development of experimental prostate cancer. Nature Medicine. 9: 1265-6. PMID 12960963 DOI: 10.1038/Nm928  1
2003 Nicolaou KC, Evans RM, Roecker AJ, Hughes R, Downes M, Pfefferkorn JA. Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries. Organic & Biomolecular Chemistry. 1: 908-20. PMID 12929628 DOI: 10.1039/B300525A  1
2003 McClelland D, Evans RM, Abidin I, Sharma S, Choudhry FZ, Jaspars M, Sepcić K, Scott RH. Irreversible and reversible pore formation by polymeric alkylpyridinium salts (poly-APS) from the sponge Reniera sarai. British Journal of Pharmacology. 139: 1399-408. PMID 12922926 DOI: 10.1038/Sj.Bjp.0705374  1
2003 Lee CH, Olson P, Evans RM. Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. Endocrinology. 144: 2201-7. PMID 12746275 DOI: 10.1210/En.2003-0288  1
2003 Downes M, Verdecia MA, Roecker AJ, Hughes R, Hogenesch JB, Kast-Woelbern HR, Bowman ME, Ferrer JL, Anisfeld AM, Edwards PA, Rosenfeld JM, Alvarez JG, Noel JP, Nicolaou KC, Evans RM. A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR. Molecular Cell. 11: 1079-92. PMID 12718892 DOI: 10.1016/S1097-2765(03)00104-7  1
2003 Wang YX, Lee CH, Tiep S, Yu RT, Ham J, Kang H, Evans RM. Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. Cell. 113: 159-70. PMID 12705865 DOI: 10.1016/S0092-8674(03)00269-1  1
2003 Rosenfeld JM, Vargas R, Xie W, Evans RM. Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor. Molecular Endocrinology (Baltimore, Md.). 17: 1268-82. PMID 12663745 DOI: 10.1210/me.2002-0421  1
2003 Gearhart MD, Holmbeck SM, Evans RM, Dyson HJ, Wright PE. Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition. Journal of Molecular Biology. 327: 819-32. PMID 12654265 DOI: 10.1016/S0022-2836(03)00183-9  1
2003 Xie W, Yeuh MF, Radominska-Pandya A, Saini SP, Negishi Y, Bottroff BS, Cabrera GY, Tukey RH, Evans RM. Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor. Proceedings of the National Academy of Sciences of the United States of America. 100: 4150-5. PMID 12644700 DOI: 10.1073/Pnas.0438010100  1
2003 Stenman J, Yu RT, Evans RM, Campbell K. Tlx and Pax6 co-operate genetically to establish the pallio-subpallial boundary in the embryonic mouse telencephalon. Development (Cambridge, England). 130: 1113-22. PMID 12571103 DOI: 10.1242/Dev.00328  1
2003 Sonoda J, Rosenfeld JM, Xu L, Evans RM, Xie W. A nuclear receptor-mediated xenobiotic response and its implication in drug metabolism and host protection. Current Drug Metabolism. 4: 59-72. PMID 12570746 DOI: 10.2174/1389200033336739  1
2003 Miles PD, Barak Y, Evans RM, Olefsky JM. Effect of heterozygous PPARgamma deficiency and TZD treatment on insulin resistance associated with age and high-fat feeding. American Journal of Physiology. Endocrinology and Metabolism. 284: E618-26. PMID 12556354 DOI: 10.1152/Ajpendo.00312.2002  1
2003 Chawla A, Lee CH, Barak Y, He W, Rosenfeld J, Liao D, Han J, Kang H, Evans RM. PPARdelta is a very low-density lipoprotein sensor in macrophages. Proceedings of the National Academy of Sciences of the United States of America. 100: 1268-73. PMID 12540828 DOI: 10.1073/Pnas.0337331100  1
2003 Haubold K, Herrmann H, Langer SJ, Evans RM, Leinwand LA, Klymkowsky MW. Acute effects of desmin mutations on cytoskeletal and cellular integrity in cardiac myocytes. Cell Motility and the Cytoskeleton. 54: 105-21. PMID 12529857 DOI: 10.1002/Cm.10090  1
2003 Desai PP, Hendrie HC, Evans RM, Murrell JR, DeKosky ST, Kamboh MI. Genetic variation in apolipoprotein D affects the risk of Alzheimer disease in African-Americans. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 116: 98-101. PMID 12497622 DOI: 10.1002/Ajmg.B.10798  1
2003 Kao HY, Han CC, Komar AA, Evans RM. Co-repressor release but not ligand binding is a prerequisite for transcription activation by human retinoid acid receptor alpha ligand-binding domain. The Journal of Biological Chemistry. 278: 7366-73. PMID 12468549 DOI: 10.1074/Jbc.M207569200  1
2003 Sonoda J, Evans RM. Biological function and mode of action of nuclear xenobiotic receptors Pure and Applied Chemistry. 75: 1733-1742. DOI: 10.1351/Pac200375111733  0.01
2002 Matsuyama A, Evans RM, Cates ME. Non-uniformities in polymer/liquid crystal mixtures II. Nematic nucleation. The European Physical Journal. E, Soft Matter. 9: 89-95. PMID 15010934 DOI: 10.1140/epje/i2002-10062-8  1
2002 Matsuyama A, Evans RM, Cates ME. Non-uniformities in polymer/liquid crystal mixtures I. Interfacial tension. The European Physical Journal. E, Soft Matter. 9: 79-87. PMID 15010933 DOI: 10.1140/epje/i2002-10061-9  1
2002 Murray MD, Lane KA, Gao S, Evans RM, Unverzagt FW, Hall KS, Hendrie H. Preservation of cognitive function with antihypertensive medications: a longitudinal analysis of a community-based sample of African Americans. Archives of Internal Medicine. 162: 2090-6. PMID 12374517 DOI: 10.1001/Archinte.162.18.2090  1
2002 Sonoda J, Xie W, Rosenfeld JM, Barwick JL, Guzelian PS, Evans RM. Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR). Proceedings of the National Academy of Sciences of the United States of America. 99: 13801-6. PMID 12370413 DOI: 10.1073/Pnas.212494599  1
2002 Lee CH, Evans RM. Peroxisome proliferator-activated receptor-gamma in macrophage lipid homeostasis. Trends in Endocrinology and Metabolism: Tem. 13: 331-5. PMID 12217489 DOI: 10.1016/S1043-2760(02)00668-9  1
2002 Evans RM. Interview with Rupert Evans, Sr., FACHE, president, Institute for Diversity in Health Management. Interview by Kyle Grazier. Journal of Healthcare Management / American College of Healthcare Executives. 47: 143-7. PMID 12055895  0.01
2002 Makishima M, Lu TT, Xie W, Whitfield GK, Domoto H, Evans RM, Haussler MR, Mangelsdorf DJ. Vitamin D receptor as an intestinal bile acid sensor. Science (New York, N.Y.). 296: 1313-6. PMID 12016314 DOI: 10.1126/Science.1070477  1
2002 Xie W, Evans RM. Pharmaceutical use of mouse models humanized for the xenobiotic receptor. Drug Discovery Today. 7: 509-15. PMID 11983567 DOI: 10.1016/S1359-6446(02)02251-1  1
2002 Pitman JL, Tsai CC, Edeen PT, Finley KD, Evans RM, McKeown M. DSF nuclear receptor acts as a repressor in culture and in vivo. Developmental Biology. 245: 315-28. PMID 11977984 DOI: 10.1006/dbio.2002.0648  1
2002 Evans RM. A business imperative. Hospitals & Health Networks / Aha. 76: 76, 4. PMID 11974412  0.01
2002 Shi Y, Hon M, Evans RM. The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. 99: 2613-8. PMID 11867749 DOI: 10.1073/pnas.052707099  1
2002 Tini M, Benecke A, Um SJ, Torchia J, Evans RM, Chambon P. Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription. Molecular Cell. 9: 265-77. PMID 11864601 DOI: 10.1016/S1097-2765(02)00453-7  1
2002 Demarest SJ, Martinez-Yamout M, Chung J, Chen H, Xu W, Dyson HJ, Evans RM, Wright PE. Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators. Nature. 415: 549-53. PMID 11823864 DOI: 10.1038/415549A  1
2002 Love JD, Gooch JT, Benko S, Li C, Nagy L, Chatterjee VK, Evans RM, Schwabe JW. The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12. The Journal of Biological Chemistry. 277: 11385-91. PMID 11782480 DOI: 10.1074/Jbc.M110869200  1
2002 Barak Y, Liao D, He W, Ong ES, Nelson MC, Olefsky JM, Boland R, Evans RM. Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America. 99: 303-8. PMID 11756685 DOI: 10.1073/Pnas.012610299  1
2002 Kao HY, Lee CH, Komarov A, Han CC, Evans RM. Isolation and characterization of mammalian HDAC10, a novel histone deacetylase. The Journal of Biological Chemistry. 277: 187-93. PMID 11677242 DOI: 10.1074/jbc.M108931200  1
2001 Chawla A, Repa JJ, Evans RM, Mangelsdorf DJ. Nuclear receptors and lipid physiology: opening the X-files. Science (New York, N.Y.). 294: 1866-70. PMID 11729302 DOI: 10.1126/science.294.5548.1866  1
2001 Lin RJ, Sternsdorf T, Tini M, Evans RM. Transcriptional regulation in acute promyelocytic leukemia. Oncogene. 20: 7204-15. PMID 11704848 DOI: 10.1038/Sj.Onc.1204853  1
2001 Xu W, Chen H, Du K, Asahara H, Tini M, Emerson BM, Montminy M, Evans RM. A transcriptional switch mediated by cofactor methylation. Science (New York, N.Y.). 294: 2507-11. PMID 11701890 DOI: 10.1126/Science.1065961  1
2001 Evans RM. Herbal medicine in neuropsychiatry. Australian Family Physician. 30: 735. PMID 11681140  0.01
2001 Evans RM, Poon WC, Renth F. Classification of ordering kinetics in three-phase systems. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 64: 031403. PMID 11580335  1
2001 Renth F, Poon WC, Evans RM. Phase transition kinetics in colloid-polymer mixtures at triple coexistence: kinetic maps from free-energy landscapes. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 64: 031402. PMID 11580334  1
2001 Misner DL, Jacobs S, Shimizu Y, de Urquiza AM, Solomin L, Perlmann T, De Luca LM, Stevens CF, Evans RM. Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. 98: 11714-9. PMID 11553775 DOI: 10.1073/pnas.191369798  1
2001 Evans RM, Holmes CB. Diffusive growth of polydisperse hard-sphere crystals. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 64: 011404. PMID 11461254  0.01
2001 Xie W, Evans RM. Orphan nuclear receptors: the exotics of xenobiotics. The Journal of Biological Chemistry. 276: 37739-42. PMID 11459851 DOI: 10.1074/jbc.R100033200  1
2001 Turelli P, Doucas V, Craig E, Mangeat B, Klages N, Evans R, Kalpana G, Trono D. Cytoplasmic recruitment of INI1 and PML on incoming HIV preintegration complexes: Interference with early steps of viral replication Molecular Cell. 7: 1245-1254. PMID 11430827 DOI: 10.1016/S1097-2765(01)00255-6  1
2001 Shi Y, Downes M, Xie W, Kao HY, Ordentlich P, Tsai CC, Hon M, Evans RM. Sharp, an inducible cofactor that integrates nuclear receptor repression and activation. Genes & Development. 15: 1140-51. PMID 11331609 DOI: 10.1101/Gad.871201  1
2001 Mundasad MV, Novack GD, Allgood VE, Evans RM, Gorden JC, Yerxa BR. Ocular safety of INS365 ophthalmic solution: a P2Y(2) agonist in healthy subjects. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 17: 173-9. PMID 11324984 DOI: 10.1089/10807680151125519  0.01
2001 Dressel U, Bailey PJ, Wang SC, Downes M, Evans RM, Muscat GE. A dynamic role for HDAC7 in MEF2-mediated muscle differentiation. The Journal of Biological Chemistry. 276: 17007-13. PMID 11279209 DOI: 10.1074/jbc.M101508200  1
2001 Ghbeish N, Tsai CC, Schubiger M, Zhou JY, Evans RM, McKeown M. The dual role of ultraspiracle, the Drosophila retinoid X receptor, in the ecdysone response. Proceedings of the National Academy of Sciences of the United States of America. 98: 3867-72. PMID 11274407 DOI: 10.1073/pnas.061437798  1
2001 Chen H, Tini M, Evans RM. HATs on and beyond chromatin. Current Opinion in Cell Biology. 13: 218-24. PMID 11248556 DOI: 10.1016/S0955-0674(00)00200-3  1
2001 Xie W, Radominska-Pandya A, Shi Y, Simon CM, Nelson MC, Ong ES, Waxman DJ, Evans RM. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proceedings of the National Academy of Sciences of the United States of America. 98: 3375-80. PMID 11248086 DOI: 10.1073/Pnas.051014398  1
2001 Schweitzer SC, Klymkowsky MW, Bellin RM, Robson RM, Capetanaki Y, Evans RM. Paranemin and the organization of desmin filament networks. Journal of Cell Science. 114: 1079-89. PMID 11228152  1
2001 Ordentlich P, Downes M, Evans RM. Corepressors and nuclear hormone receptor function. Current Topics in Microbiology and Immunology. 254: 101-16. PMID 11190569 DOI: 10.1007/978-3-662-10595-5_5  1
2001 Hendrie HC, Ogunniyi A, Hall KS, Baiyewu O, Unverzagt FW, Gureje O, Gao S, Evans RM, Ogunseyinde AO, Adeyinka AO, Musick B, Hui SL. Incidence of dementia and Alzheimer disease in 2 communities: Yoruba residing in Ibadan, Nigeria, and African Americans residing in Indianapolis, Indiana. Jama. 285: 739-47. PMID 11176911 DOI: 10.1001/Jama.285.6.739  1
2001 Chawla A, Boisvert WA, Lee CH, Laffitte BA, Barak Y, Joseph SB, Liao D, Nagy L, Edwards PA, Curtiss LK, Evans RM, Tontonoz P. A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Molecular Cell. 7: 161-71. PMID 11172721 DOI: 10.1016/S1097-2765(01)00164-2  1
2001 Clayton GM, Peak-Chew SY, Evans RM, Schwabe JW. The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation. Proceedings of the National Academy of Sciences of the United States of America. 98: 1549-54. PMID 11171988 DOI: 10.1073/pnas.041611298  1
2001 Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM. PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nature Medicine. 7: 48-52. PMID 11135615 DOI: 10.1038/83336  1
2000 Mohanty K, Gupta SK, Evans RM. Check radiography after fixation of hip fractures: is it necessary? Journal of the Royal College of Surgeons of Edinburgh. 45: 398-9. PMID 11153432  0.01
2000 Xie W, Barwick JL, Simon CM, Pierce AM, Safe S, Blumberg B, Guzelian PS, Evans RM. Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR. Genes & Development. 14: 3014-23. PMID 11114890 DOI: 10.1101/Gad.846800  1
2000 Saez E, Nelson MC, Eshelman B, Banayo E, Koder A, Cho GJ, Evans RM. Identification of ligands and coligands for the ecdysone-regulated gene switch. Proceedings of the National Academy of Sciences of the United States of America. 97: 14512-7. PMID 11114195 DOI: 10.1073/Pnas.260499497  1
2000 Chawla A, Saez E, Evans RM. "Don't know much bile-ology". Cell. 103: 1-4. PMID 11051540 DOI: 10.1016/S0092-8674(00)00097-0  1
2000 Doucas V, Shi Y, Miyamoto S, West A, Verma I, Evans RM. Cytoplasmic catalytic subunit of protein kinase A mediates cross-repression by NF-kappa B and the glucocorticoid receptor. Proceedings of the National Academy of Sciences of the United States of America. 97: 11893-8. PMID 11027313 DOI: 10.1073/Pnas.220413297  1
2000 Hodder SC, Evans RM, Patton DW, Silvester KC. Ultrasound and fine needle aspiration cytology in the staging of neck lymph nodes in oral squamous cell carcinoma. The British Journal of Oral & Maxillofacial Surgery. 38: 430-6. PMID 11010769 DOI: 10.1054/bjom.2000.0332  1
2000 Lee H, Shi W, Tontonoz P, Wang S, Subbanagounder G, Hedrick CC, Hama S, Borromeo C, Evans RM, Berliner JA, Nagy L. Role for peroxisome proliferator-activated receptor alpha in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells. Circulation Research. 87: 516-21. PMID 10988245 DOI: 10.1161/01.Res.87.6.516  1
2000 Downes M, Ordentlich P, Kao HY, Alvarez JG, Evans RM. Identification of a nuclear domain with deacetylase activity. Proceedings of the National Academy of Sciences of the United States of America. 97: 10330-5. PMID 10984530 DOI: 10.1073/Pnas.97.19.10330  1
2000 Reyland ME, Evans RM, White EK. Lipoproteins regulate expression of the steroidogenic acute regulatory protein (StAR) in mouse adrenocortical cells. The Journal of Biological Chemistry. 275: 36637-44. PMID 10960482 DOI: 10.1074/Jbc.M006456200  1
2000 Du Y, Dodel RC, Eastwood BJ, Bales KR, Gao F, Lohmüller F, Müller U, Kurz A, Zimmer R, Evans RM, Hake A, Gasser T, Oertel WH, Griffin WS, Paul SM, et al. Association of an interleukin 1 alpha polymorphism with Alzheimer's disease. Neurology. 55: 480-3. PMID 10953177 DOI: 10.1212/Wnl.55.4.480  1
2000 Xie W, Barwick JL, Downes M, Blumberg B, Simon CM, Nelson MC, Neuschwander-Tetri BA, Brunt EM, Guzelian PS, Evans RM. Humanized xenobiotic response in mice expressing nuclear receptor SXR. Nature. 406: 435-9. PMID 10935643 DOI: 10.1038/35019116  1
2000 Lin RJ, Evans RM. Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers. Molecular Cell. 5: 821-30. PMID 10882118 DOI: 10.1016/S1097-2765(00)80322-6  1
2000 Takada I, Yu RT, Xu HE, Lambert MH, Montana VG, Kliewer SA, Evans RM, Umesono K. Alteration of a single amino acid in peroxisome proliferator-activated receptor-alpha (PPAR alpha) generates a PPAR delta phenotype. Molecular Endocrinology (Baltimore, Md.). 14: 733-40. PMID 10809235 DOI: 10.1210/Mend.14.5.0456  1
2000 Yu RT, Chiang MY, Tanabe T, Kobayashi M, Yasuda K, Evans RM, Umesono K. The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision. Proceedings of the National Academy of Sciences of the United States of America. 97: 2621-5. PMID 10706625 DOI: 10.1073/pnas.050566897  1
2000 Miles PD, Barak Y, He W, Evans RM, Olefsky JM. Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency. The Journal of Clinical Investigation. 105: 287-92. PMID 10675354 DOI: 10.1172/Jci8538  1
2000 Kao HY, Downes M, Ordentlich P, Evans RM. Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression. Genes & Development. 14: 55-66. PMID 10640276 DOI: 10.1101/Gad.14.1.55  1
2000 Evans RM, Emsley CL, Gao S, Sahota A, Hall KS, Farlow MR, Hendrie H. Serum cholesterol, APOE genotype, and the risk of Alzheimer's disease: a population-based study of African Americans. Neurology. 54: 240-2. PMID 10636159 DOI: 10.1212/Wnl.54.1.240  1
1999 Evans RM. Increasing minority representation in health care management. Health Forum Journal. 42: 22. PMID 10662146  0.01
1999 Nagy L, Kao HY, Love JD, Li C, Banayo E, Gooch JT, Krishna V, Chatterjee K, Evans RM, Schwabe JW. Mechanism of corepressor binding and release from nuclear hormone receptors. Genes & Development. 13: 3209-16. PMID 10617570 DOI: 10.1101/Gad.13.24.3209  1
1999 Xie W, Hong H, Yang NN, Lin RJ, Simon CM, Stallcup MR, Evans RM. Constitutive activation of transcription and binding of coactivator by estrogen-related receptors 1 and 2. Molecular Endocrinology (Baltimore, Md.). 13: 2151-62. PMID 10598588 DOI: 10.1210/Mend.13.12.0381  1
1999 Asahara H, Dutta S, Kao HY, Evans RM, Montminy M. Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner. Molecular and Cellular Biology. 19: 8219-25. PMID 10567547 DOI: 10.1128/Mcb.19.12.8219  1
1999 Barak Y, Nelson MC, Ong ES, Jones YZ, Ruiz-Lozano P, Chien KR, Koder A, Evans RM. PPAR gamma is required for placental, cardiac, and adipose tissue development. Molecular Cell. 4: 585-95. PMID 10549290 DOI: 10.1016/S1097-2765(00)80209-9  1
1999 Murphy M, Ahn J, Walker KK, Hoffman WH, Evans RM, Levine AJ, George DL. Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes & Development. 13: 2490-501. PMID 10521394 DOI: 10.1101/Gad.13.19.2490  0.01
1999 Tsukui T, Capdevila J, Tamura K, Ruiz-Lozano P, Rodriguez-Esteban C, Yonei-Tamura S, Magallón J, Chandraratna RA, Chien K, Blumberg B, Evans RM, Belmonte JC. Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1. Proceedings of the National Academy of Sciences of the United States of America. 96: 11376-81. PMID 10500184 DOI: 10.1073/Pnas.96.20.11376  1
1999 Chen H, Lin RJ, Xie W, Wilpitz D, Evans RM. Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase. Cell. 98: 675-86. PMID 10490106 DOI: 10.1016/S0092-8674(00)80054-9  1
1999 Tsai CC, Kao HY, Yao TP, McKeown M, Evans RM. SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development. Molecular Cell. 4: 175-86. PMID 10488333 DOI: 10.1016/S1097-2765(00)80365-2  1
1999 Muhammad JK, Patton DW, Evans RM, Major E. Percutaneous dilatational tracheostomy under ultrasound guidance. The British Journal of Oral & Maxillofacial Surgery. 37: 309-11. PMID 10475654 DOI: 10.1054/bjom.1999.0072  1
1999 Holwell TA, Schweitzer SC, Reyland ME, Evans RM. Vimentin-dependent utilization of LDL-cholesterol in human adrenal tumor cells is not associated with the level of expression of apoE, sterol carrier protein-2, or caveolin. Journal of Lipid Research. 40: 1440-52. PMID 10428980  1
1999 Egan DA, Evans RM. Target acquisition and acute promyelocytic leukemia. The Journal of Clinical Investigation. 103: 1367-8. PMID 10330417 DOI: 10.1172/JCI7118  1
1999 Lin RJ, Egan DA, Evans RM. Molecular genetics of acute promyelocytic leukemia. Trends in Genetics : Tig. 15: 179-84. PMID 10322484 DOI: 10.1016/S0168-9525(99)01710-2  1
1999 Auwerx J, Baulieu E, Beato M, Becker-Andre M, Burbach PH, Camerino G, Chambon P, Cooney A, Dejean A, Dreyer C, Evans RM, Gannon F, Giguere V, Gronemeyer H, Gustafsson JA, et al. A unified nomenclature system for the nuclear receptor superfamily Cell. 97: 161-163. PMID 10219237 DOI: 10.1016/S0092-8674(00)80726-6  1
1999 Ordentlich P, Downes M, Xie W, Genin A, Spinner NB, Evans RM. Unique forms of human and mouse nuclear receptor corepressor SMRT. Proceedings of the National Academy of Sciences of the United States of America. 96: 2639-44. PMID 10077563 DOI: 10.1073/Pnas.96.6.2639  1
1999 Doucas V, Evans RM. Human T-cell leukemia retrovirus-Tax protein is a repressor of nuclear receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. 96: 2633-8. PMID 10077562 DOI: 10.1073/PNAS.96.6.2633  0.01
1999 Doucas V, Tini M, Egan DA, Evans RM. Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling Proceedings of the National Academy of Sciences of the United States of America. 96: 2627-2632. PMID 10077561 DOI: 10.1073/pnas.96.6.2627  1
1999 Chakravarti D, Ogryzko V, Kao HY, Nash A, Chen H, Nakatani Y, Evans RM. A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity. Cell. 96: 393-403. PMID 10025405 DOI: 10.1016/S0092-8674(00)80552-8  1
1999 Evans R, Hollmann HDL, Krattenthaler C, Xiang Q. Gauss sums, Jacobi sums, and p -ranks of cyclic difference sets Journal of Combinatorial Theory, Series A. 87: 74-119. DOI: 10.1006/Jcta.1998.2950  0.01
1998 Lin RJ, Kao HY, Ordentlich P, Evans RM. The transcriptional basis of steroid physiology. Cold Spring Harbor Symposia On Quantitative Biology. 63: 577-85. PMID 10384323 DOI: 10.1101/Sqb.1998.63.577  1
1998 Chiang MY, Misner D, Kempermann G, Schikorski T, Giguère V, Sucov HM, Gage FH, Stevens CF, Evans RM. An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression. Neuron. 21: 1353-61. PMID 9883728 DOI: 10.1016/S0896-6273(00)80654-6  1
1998 Blumberg B, Sabbagh W, Juguilon H, Bolado J, Meter CMV, Ong ES, Evans RM. SXR, a novel steroid and xenobiotic-sensing nuclear receptor. Genes & Development. 12: 3195-3205. PMID 9784494 DOI: 10.1101/Gad.12.20.3195  1
1998 Blumberg B, Evans RM. Orphan nuclear receptors--new ligands and new possibilities. Genes & Development. 12: 3149-55. PMID 9784489 DOI: 10.1101/Gad.12.20.3149  0.01
1998 Forman BM, Tzameli I, Choi HS, Chen J, Simha D, Seol W, Evans RM, Moore DD. Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta. Nature. 395: 612-5. PMID 9783588 DOI: 10.1038/26996  0.01
1998 Dhordain P, Lin RJ, Quief S, Lantoine D, Kerckaert JP, Evans RM, Albagli O. The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression. Nucleic Acids Research. 26: 4645-51. PMID 9753732 DOI: 10.1093/Nar/26.20.4645  1
1998 Saez E, Tontonoz P, Nelson MC, Alvarez JG, Ming UT, Baird SM, Thomazy VA, Evans RM. Activators of the nuclear receptor PPARgamma enhance colon polyp formation. Nature Medicine. 4: 1058-61. PMID 9734400 DOI: 10.1038/2042  1
1998 Ryan AK, Blumberg B, Rodriguez-Esteban C, Yonei-Tamura S, Tamura K, Tsukui T, de la Peña J, Sabbagh W, Greenwald J, Choe S, Norris DP, Robertson EJ, Evans RM, Rosenfeld MG, Izpisúa Belmonte JC. Pitx2 determines left-right asymmetry of internal organs in vertebrates. Nature. 394: 545-51. PMID 9707115 DOI: 10.1038/29004  1
1998 Kao HY, Ordentlich P, Koyano-Nakagawa N, Tang Z, Downes M, Kintner CR, Evans RM, Kadesch T. A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. Genes & Development. 12: 2269-77. PMID 9694793 DOI: 10.1101/Gad.12.15.2269  1
1998 Mueller E, Sarraf P, Tontonoz P, Evans RM, Martin KJ, Zhang M, Fletcher C, Singer S, Spiegelman BM. Terminal differentiation of human breast cancer through PPAR gamma. Molecular Cell. 1: 465-70. PMID 9660931 DOI: 10.1016/S1097-2765(00)80047-7  0.01
1998 Blanco JC, Minucci S, Lu J, Yang XJ, Walker KK, Chen H, Evans RM, Nakatani Y, Ozato K. The histone acetylase PCAF is a nuclear receptor coactivator. Genes & Development. 12: 1638-51. PMID 9620851 DOI: 10.1101/Gad.12.11.1638  0.01
1998 Blumberg B, Kang H, Bolado J, Chen H, Craig AG, Moreno TA, Umesono K, Perlmann T, De Robertis EM, Evans RM. BXR, an embryonic orphan nuclear receptor activated by a novel class of endogenous benzoate metabolites. Genes & Development. 12: 1269-77. PMID 9573044 DOI: 10.1101/Gad.12.9.1269  1
1998 Tontonoz P, Nagy L, Alvarez JG, Thomazy VA, Evans RM. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell. 93: 241-52. PMID 9568716 DOI: 10.1016/S0092-8674(00)81575-5  0.01
1998 Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell. 93: 229-40. PMID 9568715 DOI: 10.1016/S0092-8674(00)81574-3  0.01
1998 LaMorte VJ, Dyck JA, Ochs RL, Evans RM. Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body. Proceedings of the National Academy of Sciences of the United States of America. 95: 4991-6. PMID 9560216 DOI: 10.1073/PNAS.95.9.4991  0.04
1998 Lin RJ, Nagy L, Inoue S, Shao W, Miller WH, Evans RM. Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature. 391: 811-4. PMID 9486654 DOI: 10.1038/35895  1
1997 Dhordain P, Albagli O, Lin RJ, Ansieau S, Quief S, Leutz A, Kerckaert JP, Evans RM, Leprince D. Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein. Proceedings of the National Academy of Sciences of the United States of America. 94: 10762-7. PMID 9380707 DOI: 10.1073/Pnas.94.20.10762  1
1997 Forman BM, Ruan B, Chen J, Schroepfer GJ, Evans RM. The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism. Proceedings of the National Academy of Sciences of the United States of America. 94: 10588-93. PMID 9380679 DOI: 10.1073/Pnas.94.20.10588  0.04
1997 Saez E, No D, West A, Evans RM. Inducible gene expression in mammalian cells and transgenic mice Current Opinion in Biotechnology. 8: 608-616. PMID 9353233 DOI: 10.1016/S0958-1669(97)80037-7  1
1997 Süsens U, Aguiluz JB, Evans RM, Borgmeyer U. The germ cell nuclear factor mGCNF is expressed in the developing nervous system. Developmental Neuroscience. 19: 410-20. PMID 9323461 DOI: 10.1159/000111238  0.01
1997 Li C, Evans RM. Ligation independent cloning irrespective of restriction site compatibility Nucleic Acids Research. 25: 4165-4166. PMID 9321675 DOI: 10.1093/Nar/25.20.4165  1
1997 Chen H, Lin RJ, Schiltz RL, Chakravarti D, Nash A, Nagy L, Privalsky ML, Nakatani Y, Evans RM. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell. 90: 569-80. PMID 9267036 DOI: 10.1016/S0092-8674(00)80516-4  1
1997 Perlmann T, Evans RM. Nuclear receptors in Sicily: all in the famiglia. Cell. 90: 391-7. PMID 9267019 DOI: 10.1016/S0092-8674(00)80498-5  0.04
1997 Sem DS, Casimiro DR, Kliewer SA, Provencal J, Evans RM, Wright PE. NMR spectroscopic studies of the DNA-binding domain of the monomer-binding nuclear orphan receptor, human estrogen related receptor-2. The carboxyl-terminal extension to the zinc-finger region is unstructured in the free form of the protein. The Journal of Biological Chemistry. 272: 18038-43. PMID 9218433 DOI: 10.1074/Jbc.272.29.18038  0.01
1997 Lee RY, Luo J, Evans RM, Giguere V, Sucov HM. Compartment-selective sensitivity of cardiovascular morphogenesis to combinations of retinoic acid receptor gene mutations Circulation Research. 80: 757-764. PMID 9168777 DOI: 10.1161/01.Res.80.6.757  1
1997 Nagy L, Kao HY, Chakravarti D, Lin RJ, Hassig CA, Ayer DE, Schreiber SL, Evans RM. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell. 89: 373-80. PMID 9150137 DOI: 10.1016/S0092-8674(00)80218-4  1
1997 Li C, Schwabe JW, Banayo E, Evans RM. Coexpression of nuclear receptor partners increases their solubility and biological activities. Proceedings of the National Academy of Sciences of the United States of America. 94: 2278-83. PMID 9122185 DOI: 10.1073/PNAS.94.6.2278  0.08
1997 Forman BM, Chen J, Evans RM. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proceedings of the National Academy of Sciences of the United States of America. 94: 4312-7. PMID 9113986 DOI: 10.1073/PNAS.94.9.4312  0.01
1997 Schulman IG, Li C, Schwabe JW, Evans RM. The phantom ligand effect: allosteric control of transcription by the retinoid X receptor. Genes & Development. 11: 299-308. PMID 9030683 DOI: 10.1101/gad.11.3.299  0.01
1997 Doucas V, Evans RM. The PML nuclear compartment and cancer. Biochimica Et Biophysica Acta. 1288: M25-9. PMID 9011178 DOI: 10.1016/S0304-419X(96)00028-5  0.01
1997 Forman BM, Chen J, Evans RM. The peroxisome proliferator-activated receptors: ligands and activators. Annals of the New York Academy of Sciences. 804: 266-75. PMID 8993549 DOI: 10.1111/j.1749-6632.1996.tb18621.x  0.01
1997 Tontonoz P, Singer S, Forman BM, Sarraf P, Fletcher JA, Fletcher CD, Brun RP, Mueller E, Altiok S, Oppenheim H, Evans RM, Spiegelman BM. Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor. Proceedings of the National Academy of Sciences of the United States of America. 94: 237-41. PMID 8990192 DOI: 10.1073/Pnas.94.1.237  1
1996 Perlmann T, Umesono K, Rangarajan PN, Forman BM, Evans RM. Two distinct dimerization interfaces differentially modulate target gene specificity of nuclear hormone receptors. Molecular Endocrinology (Baltimore, Md.). 10: 958-66. PMID 8843412 DOI: 10.1210/mend.10.8.8843412  1
1996 Lala DS, Mukherjee R, Schulman IG, Koch SS, Dardashti LJ, Nadzan AM, Croston GE, Evans RM, Heyman RA. Activation of specific RXR heterodimers by an antagonist of RXR homodimers. Nature. 383: 450-3. PMID 8837780 DOI: 10.1038/383450a0  0.01
1996 Gruber PJ, Kubalak SW, Pexieder T, Sucov HM, Evans RM, Chien KR. RXRα deficiency confers genetic susceptibility for aortic sac, conotruncal, atrioventricular cushion, and ventricular muscle defects in mice Journal of Clinical Investigation. 98: 1332-1343. PMID 8823298 DOI: 10.1172/Jci118920  1
1996 Chakravarti D, LaMorte VJ, Nelson MC, Nakajima T, Schulman IG, Juguilon H, Montminy M, Evans RM. Role of CBP/P300 in nuclear receptor signalling. Nature. 383: 99-103. PMID 8779723 DOI: 10.1038/383099A0  1
1996 Early E, Moore MA, Kakizuka A, Nason-Burchenal K, Martin P, Evans RM, Dmitrovsky E. Transgenic expression of PML/RARalpha impairs myelopoiesis. Proceedings of the National Academy of Sciences of the United States of America. 93: 7900-4. PMID 8755574 DOI: 10.1073/Pnas.93.15.7900  0.01
1996 Chen JD, Umesono K, Evans RM. SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers. Proceedings of the National Academy of Sciences of the United States of America. 93: 7567-71. PMID 8755515 DOI: 10.1073/pnas.93.15.7567  0.01
1996 Luo J, Sucov HM, Bader JA, Evans RM, Giguère V. Compound mutants for retinoic acid receptor (RAR) β and RARα1 reveal developmental functions for multiple RARβ isoforms Mechanisms of Development. 55: 33-44. PMID 8734497 DOI: 10.1016/0925-4773(95)00488-2  1
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