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Ronald M. Evans - Publications

Salk Institute for Biological Studies, La Jolla, CA, United States 
hormone, gene expression

429 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Fu T, Li Y, Oh TG, Cayabyab F, He N, Tang Q, Coulter S, Truitt M, Medina P, He M, Yu RT, Atkins A, Zheng Y, Liddle C, Downes M, ... Evans RM, et al. FXR mediates ILC-intrinsic responses to intestinal inflammation. Proceedings of the National Academy of Sciences of the United States of America. 119: e2213041119. PMID 36508655 DOI: 10.1073/pnas.2213041119  0.461
2022 Choi J, Oh TG, Jung H, Park KY, Shin H, Jo T, Kang DS, Chanda D, Hong S, Kim J, Hwang H, Ji M, Jung M, Matsushima A, Kim P, ... ... Evans RM, et al. Estrogen-Related Receptor γ maintains pancreatic acinar cell function and identity by regulating cellular metabolism. Gastroenterology. PMID 35461826 DOI: 10.1053/j.gastro.2022.04.013  0.789
2022 Bapat SP, Whitty C, Mowery CT, Liang Y, Yoo A, Jiang Z, Peters MC, Zhang LJ, Vogel I, Zhou C, Nguyen VQ, Li Z, Chang C, Zhu WS, Hastie AT, ... ... Evans RM, et al. Obesity alters pathology and treatment response in inflammatory disease. Nature. PMID 35355021 DOI: 10.1038/s41586-022-04536-0  0.778
2020 Paschoal VA, Walenta E, Talukdar S, Pessentheiner AR, Osborn O, Hah N, Chi TJ, Tye GL, Armando AM, Evans RM, Chi NW, Quehenberger O, Olefsky JM, Oh DY. Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity. Cell Metabolism. PMID 32413335 DOI: 10.1016/J.Cmet.2020.04.020  0.303
2020 Seidman JS, Troutman TD, Sakai M, Gola A, Spann NJ, Bennett H, Bruni CM, Ouyang Z, Li RZ, Sun X, Vu BT, Pasillas MP, Ego KM, Gosselin D, Link VM, ... ... Evans RM, et al. Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis. Immunity. PMID 32362324 DOI: 10.1016/J.Immuni.2020.04.001  0.315
2020 Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, ... ... Evans RM, et al. Global chemical effects of the microbiome include new bile-acid conjugations. Nature. PMID 32103176 DOI: 10.1038/S41586-020-2047-9  0.309
2019 Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, Borowsky AD, Bold RJ, Lara PN, Li JJ, Chen X, ... ... Evans RM, et al. RORγ is a targetable master regulator of cholesterol biosynthesis in a cancer subtype. Nature Communications. 10: 4621. PMID 31604910 DOI: 10.1038/S41467-019-12529-3  0.321
2019 Chang C, Loo CS, Zhao X, Solt LA, Liang Y, Bapat SP, Cho H, Kamenecka TM, Leblanc M, Atkins AR, Yu RT, Downes M, Burris TP, Evans RM, Zheng Y. The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 31455731 DOI: 10.1073/Pnas.1907563116  0.805
2019 Wang L, Mazagova M, Pan C, Yang S, Brandl K, Liu J, Reilly SM, Wang Y, Miao Z, Loomba R, Lu N, Guo Q, Liu J, Yu RT, Downes M, ... Evans RM, et al. YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31289229 DOI: 10.1073/Pnas.1904360116  0.364
2019 Shi Y, Gao W, Lytle NK, Huang P, Yuan X, Dann AM, Ridinger-Saison M, DelGiorno KE, Antal CE, Liang G, Atkins AR, Erikson G, Sun H, Meisenhelder J, Terenziani E, ... ... Evans RM, et al. Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring. Nature. PMID 30996350 DOI: 10.1038/S41586-019-1130-6  0.302
2019 Auciello FR, Bulusu V, Oon C, Tait-Mulder J, Berry M, Bhattacharyya S, Tumanov S, Allen-Petersen BL, Link J, Kendsersky ND, Vringer E, Schug M, Novo D, Hwang RF, Evans RM, et al. A stromal lysolipid-autotaxin signaling axis promotes pancreatic tumor progression. Cancer Discovery. PMID 30837243 DOI: 10.1158/2159-8290.Cd-18-1212  0.316
2019 Fu T, Coulter S, Yoshihara E, Oh TG, Fang S, Cayabyab F, Zhu Q, Zhang T, Leblanc M, Liu S, He M, Waizenegger W, Gasser E, Schnabl B, Atkins AR, ... ... Evans RM, et al. FXR Regulates Intestinal Cancer Stem Cell Proliferation. Cell. 176: 1098-1112.e18. PMID 30794774 DOI: 10.1016/J.Cell.2019.01.036  0.323
2019 Hemmer MC, Wierer M, Schachtrup K, Downes M, Hübner N, Evans RM, Uhlenhaut NH. E47 modulates hepatic glucocorticoid action. Nature Communications. 10: 306. PMID 30659202 DOI: 10.1038/s41467-018-08196-5  0.347
2019 Liang G, Hah N, Shi Y, Truitt ML, Antal CE, Atkins AR, Fraser C, Banayo E, Bashi S, Dai Y, Sherman M, Liddle C, Yu RT, Hunter T, Han H, ... ... Evans RM, et al. Abstract A29: Bicompartmental regulation of disease-related gene networks by histone deacetylase inhibition curbs pancreatic cancer progression Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A29  0.32
2019 Liu H, Ho WW, Naxerova K, Grahovac J, Nia H, Chen I, Posada JM, Schanne DH, Pinter M, Crain J, Qi X, Clark JW, Hong TS, Ryan DP, Huang P, ... ... Evans RM, et al. Abstract A18: Angiotensin receptor blockers normalize the pancreatic ductal adenocarcinoma stroma by reprogramming carcinoma-associated fibroblasts Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A18  0.343
2018 Senagolage MD, Sommars MA, Ramachandran K, Futtner CR, Omura Y, Allred AL, Wang J, Yang C, Procissi D, Evans RM, Han X, Bederman IR, Barish GD. Loss of Transcriptional Repression by BCL6 Confers Insulin Sensitivity in the Setting of Obesity. Cell Reports. 25: 3283-3298.e6. PMID 30566857 DOI: 10.1016/J.Celrep.2018.11.074  0.341
2018 Hong SH, Fang S, Lu BC, Nofsinger R, Kawakami Y, Castro GL, Yin Y, Lin C, Yu RT, Downes M, Izpisúa Belmonte JC, Shilatifard A, Evans RM. Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30254164 DOI: 10.1073/Pnas.1809480115  0.813
2018 Wei Z, Yoshihara E, He N, Hah N, Fan W, Pinto AFM, Huddy T, Wang Y, Ross B, Estepa G, Dai Y, Ding N, Sherman MH, Fang S, Zhao X, ... ... Evans RM, et al. Vitamin D Switches BAF Complexes to Protect β Cells. Cell. PMID 29754817 DOI: 10.1016/J.Cell.2018.04.013  0.304
2018 Magida JA, Evans RM. Rational application of macrophage-specific LXR agonists avoids the pitfalls of SREBP-induced lipogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29712848 DOI: 10.1073/pnas.1805128115  0.375
2018 Ahmadian M, Liu S, Reilly SM, Hah N, Fan W, Yoshihara E, Jha P, De Magalhaes Filho CD, Jacinto S, Gomez AV, Dai Y, Yu RT, Liddle C, Atkins AR, Auwerx J, ... ... Evans RM, et al. ERRγ Preserves Brown Fat Innate Thermogenic Activity. Cell Reports. 22: 2849-2859. PMID 29539415 DOI: 10.1016/J.Celrep.2018.02.061  0.367
2018 Fan W, He N, Lin CS, Wei Z, Hah N, Waizenegger W, He MX, Liddle C, Yu RT, Atkins AR, Downes M, Evans RM. ERRγ Promotes Angiogenesis, Mitochondrial Biogenesis, and Oxidative Remodeling in PGC1α/β-Deficient Muscle. Cell Reports. 22: 2521-2529. PMID 29514081 DOI: 10.1016/J.Celrep.2018.02.047  0.315
2018 Shalom-Barak T, Liersemann J, Memari B, Flechner L, Devor C, Bernardo TM, Kim S, Matsumoto N, Friedman SL, Evans RM, White JH, Barak Y. Ligand-Dependent Corepressor (LCoR) Is A Rexinoid-Inhibited PPARγ-RXRα Coactivator. Molecular and Cellular Biology. PMID 29463649 DOI: 10.1128/Mcb.00107-17  0.423
2017 Dickey AS, Sanchez DN, Arreola M, Sampat KR, Fan W, Arbez N, Akimov S, Van Kanegan MJ, Ohnishi K, Gilmore-Hall SK, Flores AL, Nguyen JM, Lomas N, Hsu CL, Lo DC, ... ... Evans RM, et al. PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis. Science Translational Medicine. 9. PMID 29212711 DOI: 10.1126/Scitranslmed.Aal2332  0.369
2017 Hartmann P, Hochrath K, Horvath A, Chen P, Seebauer CT, Llorente C, Wang L, Alnouti Y, Fouts DE, Stärkel P, Loomba R, Coulter S, Liddle C, Yu RT, Ling L, ... ... Evans RM, et al. Modulation of the intestinal bile acid-FXR-FGF15 axis improves alcoholic liver disease in mice. Hepatology (Baltimore, Md.). PMID 29159825 DOI: 10.1002/Hep.29676  0.319
2017 Cao Q, Zhao X, Bai J, Gery S, Sun H, Lin DC, Chen Q, Chen Z, Mack L, Yang H, Deng R, Shi X, Chong LW, Cho H, Xie J, ... ... Evans RM, et al. Circadian clock cryptochrome proteins regulate autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. PMID 29109286 DOI: 10.1073/Pnas.1619119114  0.538
2017 He N, Fan W, Henriquez B, Yu RT, Atkins AR, Liddle C, Zheng Y, Downes M, Evans RM. Metabolic control of regulatory T cell (Treg) survival and function by Lkb1. Proceedings of the National Academy of Sciences of the United States of America. PMID 29109251 DOI: 10.1073/Pnas.1715363114  0.527
2017 Wang J, He N, Zhang N, Quan D, Zhang S, Zhang C, Yu RT, Atkins AR, Zhu R, Yang C, Cui Y, Liddle C, Downes M, Xiao H, Zheng Y, ... ... Evans RM, et al. NCoR1 restrains thymic negative selection by repressing Bim expression to spare thymocytes undergoing positive selection. Nature Communications. 8: 959. PMID 29038463 DOI: 10.1038/S41467-017-00931-8  0.505
2017 Kriebs A, Jordan SD, Soto E, Henriksson E, Sandate CR, Vaughan ME, Chan AB, Duglan D, Papp SJ, Huber AL, Afetian ME, Yu RT, Zhao X, Downes M, Evans RM, et al. Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28751364 DOI: 10.1073/Pnas.1704955114  0.39
2017 Jordan SD, Kriebs A, Vaughan M, Duglan D, Fan W, Henriksson E, Huber AL, Papp SJ, Nguyen M, Afetian M, Downes M, Yu RT, Kralli A, Evans RM, Lamia KA. CRY1/2 Selectively Repress PPARδ and Limit Exercise Capacity. Cell Metabolism. 26: 243-255.e6. PMID 28683290 DOI: 10.1016/J.Cmet.2017.06.002  0.333
2017 Evans RM. 30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Short reflections on the discovery of the mineralocorticoid receptor. The Journal of Endocrinology. 234: E1-E2. PMID 28634263 DOI: 10.1530/JOE-17-0287  0.357
2017 Fan W, Waizenegger W, Lin CS, Sorrentino V, He MX, Wall CE, Li H, Liddle C, Yu RT, Atkins AR, Auwerx J, Downes M, Evans RM. PPARδ Promotes Running Endurance by Preserving Glucose. Cell Metabolism. 25: 1186-1193.e4. PMID 28467934 DOI: 10.1016/j.cmet.2017.04.006  0.307
2017 Doktorova M, Zwarts I, Zutphen TV, Dijk TH, Bloks VW, Harkema L, Bruin A, Downes M, Evans RM, Verkade HJ, Jonker JW. Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia. Scientific Reports. 7: 846. PMID 28404991 DOI: 10.1038/s41598-017-00889-z  0.371
2017 Evan GI, Hah N, Littlewood TD, Sodir NM, Campos T, Downes M, Evans RM. Re-engineering the Pancreas Tumor Microenvironment: A "Regenerative Program" Hacked. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 23: 1647-1655. PMID 28373363 DOI: 10.1158/1078-0432.Ccr-16-3275  0.31
2017 Wu CC, Baiga TJ, Downes M, La Clair JJ, Atkins AR, Richard SB, Fan W, Stockley-Noel TA, Bowman ME, Noel JP, Evans RM. Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ. Proceedings of the National Academy of Sciences of the United States of America. PMID 28320959 DOI: 10.1073/Pnas.1621513114  0.365
2017 De Magalhaes Filho CD, Downes M, Evans RM. Farnesoid X Receptor an Emerging Target to Combat Obesity. Digestive Diseases (Basel, Switzerland). 35: 185-190. PMID 28249279 DOI: 10.1159/000450909  0.351
2017 Chen S, Lu W, Yueh MF, Rettenmeier E, Liu M, Auwerx J, Yu RT, Evans RM, Wang K, Karin M, Tukey RH. Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia. Proceedings of the National Academy of Sciences of the United States of America. PMID 28167773 DOI: 10.1073/Pnas.1700232114  0.356
2017 Sherman MH, Yu RT, Tseng TW, Sousa CM, Liu S, Truitt ML, He N, Ding N, Liddle C, Atkins AR, Leblanc M, Collisson EA, Asara JM, Kimmelman AC, Downes M, ... Evans RM, et al. Stromal cues regulate the pancreatic cancer epigenome and metabolome. Proceedings of the National Academy of Sciences of the United States of America. PMID 28096419 DOI: 10.1073/Pnas.1620164114  0.328
2016 Chung HK, Ryu D, Kim KS, Chang JY, Kim YK, Yi HS, Kang SG, Choi MJ, Lee SE, Jung SB, Ryu MJ, Kim SJ, Kweon GR, Kim H, Hwang JH, ... ... Evans RM, et al. Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis. The Journal of Cell Biology. PMID 27986797 DOI: 10.1083/Jcb.201607110  0.338
2016 Evans RM, Wan Y. Reply to "PPAR-γ regulates pharmacological but not physiological or pathological osteoclast formation". Nature Medicine. 22: 1205. PMID 27824815 DOI: 10.1038/Nm.4207  0.318
2016 Xia X, Kumru OS, Blaber SI, Middaugh CR, Li L, Ornitz DM, Suh JM, Atkins AR, Downes M, Evans RM, Tenorio CA, Bienkiewicz E, Blaber M. An S116R Phosphorylation Site Mutation in Human Fibroblast Growth Factor-1 Differentially Affects Mitogenic and Glucose-Lowering Activities. Journal of Pharmaceutical Sciences. 105: 3507-3519. PMID 27773526 DOI: 10.1016/J.Xphs.2016.09.005  0.358
2016 Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC. Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion. Nature. PMID 27509858 DOI: 10.1038/Nature19084  0.315
2016 Eichenfield DZ, Troutman TD, Link VM, Lam MT, Cho H, Gosselin D, Spann NJ, Lesch HP, Tao J, Muto J, Gallo RL, Evans RM, Glass CK. Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages. Elife. 5. PMID 27462873 DOI: 10.7554/Elife.13024  0.322
2016 Zhao X, Hirota T, Han X, Cho H, Chong LW, Lamia K, Liu S, Atkins AR, Banayo E, Liddle C, Yu RT, Yates JR, Kay SA, Downes M, Evans RM. Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation. Cell. 165: 1644-57. PMID 27238018 DOI: 10.1016/J.Cell.2016.05.012  0.323
2016 Hulin JA, Nguyen TD, Cui S, Marri S, Yu RT, Downes M, Evans RM, Makarenkova H, Meech R. Barx2 and Pax7 regulate Axin2 expression in myoblasts by interaction with β-catenin and chromatin remodelling. Stem Cells (Dayton, Ohio). PMID 27144473 DOI: 10.1002/stem.2396  0.331
2016 Evans RM, Wall CE, Yu RT, Atkins AR, Downes M. Nuclear receptors and AMPK: can exercise mimetics cure diabetes? Journal of Molecular Endocrinology. PMID 27106806 DOI: 10.1530/JME-16-0073  0.304
2016 Yoshihara E, Wei Z, Lin CS, Fang S, Ahmadian M, Kida Y, Tseng T, Dai Y, Yu RT, Liddle C, Atkins AR, Downes M, Evans RM. ERRγ Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive β Cells. Cell Metabolism. 23: 622-34. PMID 27076077 DOI: 10.1016/J.Cmet.2016.03.005  0.302
2016 Heldin CH, Lu B, Evans R, Gutkind JS. Signals and Receptors. Cold Spring Harbor Perspectives in Biology. 8. PMID 27037414 DOI: 10.1101/Cshperspect.A005900  0.409
2016 Wang J, Zou JX, Xue X, Cai D, Zhang Y, Duan Z, Xiang Q, Yang JC, Louie MC, Borowsky AD, Gao AC, Evans CP, Lam KS, Xu J, Kung HJ, ... Evans RM, et al. ROR-γ drives androgen receptor expression and represents a therapeutic target in castration-resistant prostate cancer. Nature Medicine. PMID 27019329 DOI: 10.1038/Nm.4070  0.347
2016 Booth DR, Ding N, Parnell GP, Shahijanian F, Coulter S, Schibeci SD, Atkins AR, Stewart GJ, Evans RM, Downes M, Liddle C. Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-dependent autoimmune diseases. Genes and Immunity. PMID 26986782 DOI: 10.1038/gene.2016.12  0.324
2016 Liu W, Struik D, Nies VJ, Jurdzinski A, Harkema L, de Bruin A, Verkade HJ, Downes M, Evans RM, van Zutphen T, Jonker JW. Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 26858440 DOI: 10.1073/pnas.1525093113  0.342
2016 Hah N, Sherman MH, Yu RT, Downes M, Evans RM. Targeting Transcriptional and Epigenetic Reprogramming in Stromal Cells in Fibrosis and Cancer. Cold Spring Harbor Symposia On Quantitative Biology. PMID 26801159 DOI: 10.1101/Sqb.2015.80.027185  0.358
2016 Sherman MH, Evans RM. Abstract B03: Control of pancreatic cancer metabolism and histone acetylation by the tumor microenvironment Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-B03  0.33
2016 Ridinger M, Evans RM, Saghatelian A, Lowy AM, Wahl GM. Abstract B24: p53 mediates reprograming of cancer-associated fibroblasts in pancreatic cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-B24  0.31
2015 Nies VJ, Sancar G, Liu W, van Zutphen T, Struik D, Yu RT, Atkins AR, Evans RM, Jonker JW, Downes MR. Fibroblast Growth Factor Signaling in Metabolic Regulation. Frontiers in Endocrinology. 6: 193. PMID 26834701 DOI: 10.3389/fendo.2015.00193  0.329
2015 Ding N, Hah N, Yu RT, Sherman MH, Benner C, Leblanc M, He M, Liddle C, Downes M, Evans RM. BRD4 is a novel therapeutic target for liver fibrosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26644586 DOI: 10.1073/Pnas.1522163112  0.324
2015 Bapat SP, Myoung Suh J, Fang S, Liu S, Zhang Y, Cheng A, Zhou C, Liang Y, LeBlanc M, Liddle C, Atkins AR, Yu RT, Downes M, Evans RM, Zheng Y. Depletion of fat-resident Treg cells prevents age-associated insulin resistance. Nature. PMID 26580014 DOI: 10.1038/Nature16151  0.772
2015 Arensman MD, Nguyen P, Kershaw KM, Lay AR, Ostertag-Hill CA, Sherman MH, Downes M, Liddle C, Evans RM, Dawson DW. Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer. Molecular Cancer Research : McR. PMID 26224368 DOI: 10.1158/1541-7786.Mcr-15-0204  0.307
2015 Wall CE, Whyte J, Suh JM, Fan W, Collins B, Liddle C, Yu RT, Atkins AR, Naviaux JC, Li K, Bright AT, Alaynick WA, Downes M, Naviaux RK, Evans RM. High-fat diet and FGF21 cooperatively promote aerobic thermogenesis in mtDNA mutator mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 26124126 DOI: 10.1073/Pnas.1509930112  0.707
2015 Kim JA, Roy RR, Zhong H, Alaynick WA, Embler E, Jang C, Gomez G, Sonoda T, Evans RM, Edgerton VR. Pparδ preserves a high resistance to fatigue in the mouse medial gastrocnemius after spinal cord transection. Muscle & Nerve. PMID 26044200 DOI: 10.1002/Mus.24723  0.754
2015 Mounsey RB, Martin HL, Nelson MC, Evans RM, Teismann P. The effect of neuronal conditional knock-out of peroxisome proliferator-activated receptors in the MPTP mouse model of Parkinson's disease. Neuroscience. 300: 576-84. PMID 26028469 DOI: 10.1016/j.neuroscience.2015.05.048  0.376
2015 Jo YS, Ryu D, Maida A, Wang X, Evans RM, Schoonjans K, Auwerx J. Phosphorylation of the nuclear receptor co-repressor 1 by protein kinase B (PKB/Akt) switches its co-repressor targets in the liver. Hepatology (Baltimore, Md.). PMID 25998209 DOI: 10.1002/Hep.27907  0.397
2015 Kida YS, Kawamura T, Wei Z, Sogo T, Jacinto S, Shigeno A, Kushige H, Yoshihara E, Liddle C, Ecker JR, Yu RT, Atkins AR, Downes M, Evans RM. ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency. Cell Stem Cell. 16: 547-55. PMID 25865501 DOI: 10.1016/J.Stem.2015.03.001  0.346
2015 Pei L, Mu Y, Leblanc M, Alaynick W, Barish GD, Pankratz M, Tseng TW, Kaufman S, Liddle C, Yu RT, Downes M, Pfaff SL, Auwerx J, Gage FH, Evans RM. Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolism. Cell Metabolism. 21: 628-36. PMID 25863252 DOI: 10.1016/J.Cmet.2015.03.004  0.763
2015 Wang T, McDonald C, Petrenko NB, Leblanc M, Wang T, Giguere V, Evans RM, Patel VV, Pei L. Estrogen-related receptor α (ERRα) and ERRγ are essential coordinators of cardiac metabolism and function. Molecular and Cellular Biology. 35: 1281-98. PMID 25624346 DOI: 10.1128/Mcb.01156-14  0.352
2015 Reilly SM, Ahmadian M, Zamarron BF, Chang L, Uhm M, Poirier B, Peng X, Krause DM, Korytnaya E, Neidert A, Liddle C, Yu RT, Lumeng CN, Oral EA, Downes M, ... Evans RM, et al. A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis. Nature Communications. 6: 6047. PMID 25581158 DOI: 10.1038/Ncomms7047  0.304
2015 Hah N, Benner C, Chong LW, Yu RT, Downes M, Evans RM. Inflammation-sensitive super enhancers form domains of coordinately regulated enhancer RNAs. Proceedings of the National Academy of Sciences of the United States of America. 112: E297-302. PMID 25564661 DOI: 10.1073/Pnas.1424028112  0.381
2015 Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, ... ... Evans RM, et al. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nature Medicine. 21: 159-65. PMID 25559344 DOI: 10.1038/Nm.3760  0.349
2015 Fan W, Evans R. PPARs and ERRs: molecular mediators of mitochondrial metabolism. Current Opinion in Cell Biology. 33: 49-54. PMID 25486445 DOI: 10.1016/  0.36
2015 Cao Q, Zhao X, Gery S, Chen Z, Deng R, Sun H, Lin D, Zhao Z, Said JW, Li Q, Muschen M, Evans RM, Koeffler HP. Circadian Clock Protein CRY Controls B-Cell Intrinsic Tolerance Blood. 126: 1029-1029. DOI: 10.1182/Blood.V126.23.1029.1029  0.307
2015 Sherman MH, Ding N, Collisson EA, Downes M, Evans RM. Abstract IA9: Vitamin D: Shining light on pancreatic cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-Ia9  0.331
2015 Sherman MH, Collisson E, Downes M, Evans RM. Abstract A42: Paracrine regulation of the pancreatic cancer epigenome Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A42  0.346
2014 McKenna NJ, Evans RM, O'Malley BW. Nuclear Receptor Signaling: a home for nuclear receptor and coregulator signaling research. Nuclear Receptor Signaling. 12: e006. PMID 25614732 DOI: 10.1621/nrs.12006  0.328
2014 Yueh MF, Taniguchi K, Chen S, Evans RM, Hammock BD, Karin M, Tukey RH. The commonly used antimicrobial additive triclosan is a liver tumor promoter. Proceedings of the National Academy of Sciences of the United States of America. 111: 17200-5. PMID 25404284 DOI: 10.1073/Pnas.1419119111  0.346
2014 Sherman MH, Yu RT, Engle DD, Ding N, Atkins AR, Tiriac H, Collisson EA, Connor F, Van Dyke T, Kozlov S, Martin P, Tseng TW, Dawson DW, Donahue TR, Masamune A, ... ... Evans RM, et al. Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy. Cell. 159: 80-93. PMID 25259922 DOI: 10.1016/J.Cell.2014.08.007  0.303
2014 Takada H, Saito Y, Mituyama T, Wei Z, Yoshihara E, Jacinto S, Downes M, Evans RM, Kida YS. Methylome, transcriptome, and PPAR(γ) cistrome analyses reveal two epigenetic transitions in fat cells. Epigenetics : Official Journal of the Dna Methylation Society. 9: 1195-206. PMID 25093444 DOI: 10.4161/Epi.29856  0.311
2014 Korf K, Wodrich H, Haschke A, Ocampo C, Harder L, Gieseke F, Pollmann A, Dierck K, Prall S, Staege H, Ma H, Horstmann MA, Evans RM, Sternsdorf T. The PML domain of PML-RARα blocks senescence to promote leukemia. Proceedings of the National Academy of Sciences of the United States of America. 111: 12133-8. PMID 25092303 DOI: 10.1073/pnas.1412944111  0.364
2014 Daniel B, Nagy G, Hah N, Horvath A, Czimmerer Z, Poliska S, Gyuris T, Keirsse J, Gysemans C, Van Ginderachter JA, Balint BL, Evans RM, Barta E, Nagy L. The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages. Genes & Development. 28: 1562-77. PMID 25030696 DOI: 10.1101/Gad.242685.114  0.314
2014 Oh da Y, Walenta E, Akiyama TE, Lagakos WS, Lackey D, Pessentheiner AR, Sasik R, Hah N, Chi TJ, Cox JM, Powels MA, Di Salvo J, Sinz C, Watkins SM, Armando AM, ... ... Evans RM, et al. A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice. Nature Medicine. 20: 942-7. PMID 24997608 DOI: 10.1038/Nm.3614  0.337
2014 Zhuang L, Hulin JA, Gromova A, Tran Nguyen TD, Yu RT, Liddle C, Downes M, Evans RM, Makarenkova HP, Meech R. Barx2 and Pax7 have antagonistic functions in regulation of wnt signaling and satellite cell differentiation. Stem Cells (Dayton, Ohio). 32: 1661-73. PMID 24753152 DOI: 10.1002/stem.1674  0.315
2014 Zhao X, Cho H, Yu RT, Atkins AR, Downes M, Evans RM. Nuclear receptors rock around the clock. Embo Reports. 15: 518-28. PMID 24737872 DOI: 10.1002/Embr.201338271  0.395
2014 Lu B, Bridges D, Yang Y, Fisher K, Cheng A, Chang L, Meng ZX, Lin JD, Downes M, Yu RT, Liddle C, Evans RM, Saltiel AR. Metabolic crosstalk: molecular links between glycogen and lipid metabolism in obesity. Diabetes. 63: 2935-48. PMID 24722244 DOI: 10.2337/Db13-1531  0.354
2014 Evans RM, Mangelsdorf DJ. Nuclear Receptors, RXR, and the Big Bang. Cell. 157: 255-66. PMID 24679540 DOI: 10.1016/j.cell.2014.03.012  0.42
2014 Hong SH, Ahmadian M, Yu RT, Atkins AR, Downes M, Evans RM. Nuclear receptors and metabolism: from feast to famine. Diabetologia. 57: 860-7. PMID 24619218 DOI: 10.1007/S00125-014-3209-9  0.373
2014 Liu S, Evans RM. Metabolism: Tick, tock, a high-fat clock. Nature Reviews. Endocrinology. 10: 191-2. PMID 24590185 DOI: 10.1038/Nrendo.2014.23  0.31
2014 d'Uscio LV, He T, Santhanam AV, Tai LJ, Evans RM, Katusic ZS. Mechanisms of vascular dysfunction in mice with endothelium-specific deletion of the PPAR-δ gene. American Journal of Physiology. Heart and Circulatory Physiology. 306: H1001-10. PMID 24486511 DOI: 10.1152/ajpheart.00761.2013  0.332
2014 Evans RM. Abstract SY04-04: Vitamin D receptor stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Sy04-04  0.308
2013 Fan W, Atkins AR, Yu RT, Downes M, Evans RM. Road to exercise mimetics: targeting nuclear receptors in skeletal muscle. Journal of Molecular Endocrinology. 51: T87-T100. PMID 24280961 DOI: 10.1530/JME-13-0258  0.329
2013 Hong SH, Dvorak-Ewell M, Stevens HY, Barish GD, Castro GL, Nofsinger R, Frangos JA, Shoback D, Evans RM. Rescue of a primary myelofibrosis model by retinoid-antagonist therapy. Proceedings of the National Academy of Sciences of the United States of America. 110: 18820-5. PMID 24191050 DOI: 10.1073/Pnas.1318974110  0.784
2013 Ding N, Liddle C, Evans RM, Downes M. Hepatic actions of vitamin D receptor ligands: a sunshine option for chronic liver disease? Expert Review of Clinical Pharmacology. 6: 597-9. PMID 24164608 DOI: 10.1586/17512433.2013.841078  0.34
2013 Kittayaruksakul S, Zhao W, Xu M, Ren S, Lu J, Wang J, Downes M, Evans RM, Venkataramanan R, Chatsudthipong V, Xie W. Identification of three novel natural product compounds that activate PXR and CAR and inhibit inflammation. Pharmaceutical Research. 30: 2199-208. PMID 23896737 DOI: 10.1007/S11095-013-1101-9  0.341
2013 Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, Tanaka-Oishi Y, Benner C, Kaikkonen MU, Kim AS, Kosaka M, Lee CY, Watt A, Grossman TR, Rosenfeld MG, Evans RM, et al. Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature. 498: 511-5. PMID 23728303 DOI: 10.1038/Nature12209  0.404
2013 Du L, Bergsneider M, Mirsadraei L, Young SH, Jonker JW, Downes M, Yong WH, Evans RM, Heaney AP. Evidence for orphan nuclear receptor TR4 in the etiology of Cushing disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 8555-60. PMID 23653479 DOI: 10.1073/Pnas.1306182110  0.318
2013 Ahmadian M, Suh JM, Hah N, Liddle C, Atkins AR, Downes M, Evans RM. PPARγ signaling and metabolism: the good, the bad and the future. Nature Medicine. 19: 557-66. PMID 23652116 DOI: 10.1038/Nm.3159  0.355
2013 Ding N, Yu RT, Subramaniam N, Sherman MH, Wilson C, Rao R, Leblanc M, Coulter S, He M, Scott C, Lau SL, Atkins AR, Barish GD, Gunton JE, Liddle C, ... ... Evans RM, et al. A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response. Cell. 153: 601-13. PMID 23622244 DOI: 10.1016/J.Cell.2013.03.028  0.319
2013 Chao LC, Soto E, Hong C, Ito A, Pei L, Chawla A, Conneely OM, Tangirala RK, Evans RM, Tontonoz P. Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice. Journal of Lipid Research. 54: 806-15. PMID 23288947 DOI: 10.1194/Jlr.M034157  0.367
2013 Uhlenhaut NH, Barish GD, Yu RT, Downes M, Karunasiri M, Liddle C, Schwalie P, Hübner N, Evans RM. Insights into negative regulation by the glucocorticoid receptor from genome-wide profiling of inflammatory cistromes. Molecular Cell. 49: 158-71. PMID 23159735 DOI: 10.1016/j.molcel.2012.10.013  0.386
2013 Korf K, Wodrich H, Haschke A, Evans RM, Sternsdorf TM. The Acute Promyelocytic Leukemia-Oncoprotein PML-Raralpha Blocks Senescence and Disrupts The Atrx/Daxx Chromatin Remodeling Complex To Promote Leukemia Blood. 122: 1267-1267. DOI: 10.1182/BLOOD.V122.21.1267.1267  0.326
2012 Zhang Y, Xie Y, Berglund ED, Coate KC, He TT, Katafuchi T, Xiao G, Potthoff MJ, Wei W, Wan Y, Yu RT, Evans RM, Kliewer SA, Mangelsdorf DJ. The starvation hormone, fibroblast growth factor-21, extends lifespan in mice. Elife. 1: e00065. PMID 23066506 DOI: 10.7554/Elife.00065  0.312
2012 Chao LC, Wroblewski K, Ilkayeva OR, Stevens RD, Bain J, Meyer GA, Schenk S, Martinez L, Vergnes L, Narkar VA, Drew BG, Hong C, Boyadjian R, Hevener AL, Evans RM, et al. Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization. Journal of Lipid Research. 53: 2610-9. PMID 23028113 DOI: 10.1194/Jlr.M029355  0.324
2012 Li T, Yu RT, Atkins AR, Downes M, Tukey RH, Evans RM. Targeting the pregnane X receptor in liver injury. Expert Opinion On Therapeutic Targets. 16: 1075-83. PMID 22913318 DOI: 10.1517/14728222.2012.715634  0.305
2012 Ito K, Carracedo A, Weiss D, Arai F, Ala U, Avigan DE, Schafer ZT, Evans RM, Suda T, Lee CH, Pandolfi PP. A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. Nature Medicine. 18: 1350-8. PMID 22902876 DOI: 10.1038/Nm.2882  0.351
2012 Yueh MF, Li T, Evans RM, Hammock B, Tukey RH. Triclocarban mediates induction of xenobiotic metabolism through activation of the constitutive androstane receptor and the estrogen receptor alpha. Plos One. 7: e37705. PMID 22761658 DOI: 10.1371/Journal.Pone.0037705  0.424
2012 Iwaisako K, Haimerl M, Paik YH, Taura K, Kodama Y, Sirlin C, Yu E, Yu RT, Downes M, Evans RM, Brenner DA, Schnabl B. Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist. Proceedings of the National Academy of Sciences of the United States of America. 109: E1369-76. PMID 22538808 DOI: 10.1073/Pnas.1202464109  0.344
2012 Jonker JW, Suh JM, Atkins AR, Ahmadian M, Li P, Whyte J, He M, Juguilon H, Yin YQ, Phillips CT, Yu RT, Olefsky JM, Henry RR, Downes M, Evans RM. A PPARγ-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis. Nature. 485: 391-4. PMID 22522926 DOI: 10.1038/Nature10998  0.376
2012 Barish GD, Yu RT, Karunasiri MS, Becerra D, Kim J, Tseng TW, Tai LJ, Leblanc M, Diehl C, Cerchietti L, Miller YI, Witztum JL, Melnick AM, Dent AL, Tangirala RK, ... Evans RM, et al. The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis. Cell Metabolism. 15: 554-62. PMID 22465074 DOI: 10.1016/J.Cmet.2012.02.012  0.323
2012 Cho H, Zhao X, Hatori M, Yu RT, Barish GD, Lam MT, Chong LW, DiTacchio L, Atkins AR, Glass CK, Liddle C, Auwerx J, Downes M, Panda S, Evans RM. Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β. Nature. 485: 123-7. PMID 22460952 DOI: 10.1038/Nature11048  0.366
2012 Matsakas A, Yadav V, Lorca S, Evans RM, Narkar VA. Revascularization of ischemic skeletal muscle by estrogen-related receptor-γ. Circulation Research. 110: 1087-96. PMID 22415017 DOI: 10.1161/CIRCRESAHA.112.266478  0.304
2012 Subramaniam N, Sherman MH, Rao R, Wilson C, Coulter S, Atkins AR, Evans RM, Liddle C, Downes M. Metformin-mediated Bambi expression in hepatic stellate cells induces prosurvival Wnt/β-catenin signaling. Cancer Prevention Research (Philadelphia, Pa.). 5: 553-61. PMID 22406377 DOI: 10.1158/1940-6207.Capr-12-0053  0.356
2012 Li MD, Ruan HB, Singh JP, Zhao L, Zhao T, Azarhoush S, Wu J, Evans RM, Yang X. O-GlcNAc transferase is involved in glucocorticoid receptor-mediated transrepression. The Journal of Biological Chemistry. 287: 12904-12. PMID 22371499 DOI: 10.1074/Jbc.M111.303792  0.349
2012 Chen S, Yueh MF, Evans RM, Tukey RH. Pregnane-x-receptor controls hepatic glucuronidation during pregnancy and neonatal development in humanized UGT1 mice. Hepatology (Baltimore, Md.). 56: 658-67. PMID 22371261 DOI: 10.1002/Hep.25671  0.362
2012 Noreault-Conti TL, Fellows A, Jacobs JM, Trask HW, Strom SC, Evans RM, Wrighton SA, Sinclair PR, Sinclair JF, Nichols RC. Arsenic decreases RXRα-dependent transcription of CYP3A and suppresses immune regulators in hepatocytes. International Immunopharmacology. 12: 651-6. PMID 22310326 DOI: 10.1016/j.intimp.2012.01.008  0.366
2012 Shimozaki K, Zhang CL, Suh H, Denli AM, Evans RM, Gage FH. SRY-box-containing gene 2 regulation of nuclear receptor tailless (Tlx) transcription in adult neural stem cells. The Journal of Biological Chemistry. 287: 5969-78. PMID 22194602 DOI: 10.1074/Jbc.M111.290403  0.385
2012 Sherman MH, Downes M, Evans RM. Nuclear receptors as modulators of the tumor microenvironment. Cancer Prevention Research (Philadelphia, Pa.). 5: 3-10. PMID 22135047 DOI: 10.1158/1940-6207.Capr-11-0528  0.318
2012 Ito K, Carracedo A, Arai F, Ala U, Avigan D, Schafer Z, Evans RM, Suda T, Lee C, Pandolfi PP. A PML–PPAR-δ Pathway for Fatty Acid Oxidation Regulates Hematopoietic Stem Cell Maintenance Through the Control of Asymmetric Division. Blood. 120: 2327-2327. DOI: 10.1182/Blood.V120.21.2327.2327  0.338
2011 Fan W, Downes M, Atkins A, Yu R, Evans RM. Nuclear receptors and AMPK: resetting metabolism. Cold Spring Harbor Symposia On Quantitative Biology. 76: 17-22. PMID 22411605 DOI: 10.1101/sqb.2012.76.010470  0.368
2011 Lamia KA, Papp SJ, Yu RT, Barish GD, Uhlenhaut NH, Jonker JW, Downes M, Evans RM. Cryptochromes mediate rhythmic repression of the glucocorticoid receptor. Nature. 480: 552-6. PMID 22170608 DOI: 10.1038/Nature10700  0.459
2011 Krebs P, Fan W, Chen YH, Tobita K, Downes MR, Wood MR, Sun L, Li X, Xia Y, Ding N, Spaeth JM, Moresco EM, Boyer TG, Lo CW, Yen J, ... Evans RM, et al. Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet. Proceedings of the National Academy of Sciences of the United States of America. 108: 19678-82. PMID 22106289 DOI: 10.1073/Pnas.1117835108  0.336
2011 Yamamoto H, Williams EG, Mouchiroud L, Cantó C, Fan W, Downes M, Héligon C, Barish GD, Desvergne B, Evans RM, Schoonjans K, Auwerx J. NCoR1 is a conserved physiological modulator of muscle mass and oxidative function. Cell. 147: 827-39. PMID 22078881 DOI: 10.1016/j.cell.2011.10.017  0.333
2011 Pei L, Leblanc M, Barish G, Atkins A, Nofsinger R, Whyte J, Gold D, He M, Kawamura K, Li HR, Downes M, Yu RT, Powell HC, Lingrel JB, Evans RM. Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome. Nature Medicine. 17: 1466-72. PMID 22001906 DOI: 10.1038/Nm.2450  0.791
2011 Murphy SH, Suzuki K, Downes M, Welch GL, De Jesus P, Miraglia LJ, Orth AP, Chanda SK, Evans RM, Verma IM. Tumor suppressor protein (p)53, is a regulator of NF-kappaB repression by the glucocorticoid receptor. Proceedings of the National Academy of Sciences of the United States of America. 108: 17117-22. PMID 21949408 DOI: 10.1073/Pnas.1114420108  0.345
2011 Sugii S, Evans RM. Epigenetic codes of PPARγ in metabolic disease. Febs Letters. 585: 2121-8. PMID 21605560 DOI: 10.1016/J.Febslet.2011.05.007  0.41
2011 Mihaylova MM, Vasquez DS, Ravnskjaer K, Denechaud PD, Yu RT, Alvarez JG, Downes M, Evans RM, Montminy M, Shaw RJ. Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis. Cell. 145: 607-21. PMID 21565617 DOI: 10.1016/J.Cell.2011.03.043  0.325
2011 Kacevska M, Downes MR, Sharma R, Evans RM, Clarke SJ, Liddle C, Robertson GR. Extrahepatic cancer suppresses nuclear receptor-regulated drug metabolism. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3170-80. PMID 21498392 DOI: 10.1158/1078-0432.CCR-10-3289  0.413
2011 Narkar VA, Fan W, Downes M, Yu RT, Jonker JW, Alaynick WA, Banayo E, Karunasiri MS, Lorca S, Evans RM. Exercise and PGC-1α-independent synchronization of type I muscle metabolism and vasculature by ERRγ. Cell Metabolism. 13: 283-93. PMID 21356518 DOI: 10.1016/J.Cmet.2011.01.019  0.709
2011 Fang S, Suh JM, Atkins AR, Hong SH, Leblanc M, Nofsinger RR, Yu RT, Downes M, Evans RM. Corepressor SMRT promotes oxidative phosphorylation in adipose tissue and protects against diet-induced obesity and insulin resistance. Proceedings of the National Academy of Sciences of the United States of America. 108: 3412-7. PMID 21300871 DOI: 10.1073/Pnas.1017707108  0.801
2011 Diehl CJ, Barish GD, Downes M, Chou MY, Heinz S, Glass CK, Evans RM, Witztum JL. Research resource: Comparative nuclear receptor atlas: basal and activated peritoneal B-1 and B-2 cells. Molecular Endocrinology (Baltimore, Md.). 25: 529-45. PMID 21273443 DOI: 10.1210/Me.2010-0384  0.331
2011 Berry R, Harewood L, Pei L, Fisher M, Brownstein D, Ross A, Alaynick WA, Moss J, Hastie ND, Hohenstein P, Davies JA, Evans RM, FitzPatrick DR. Esrrg functions in early branch generation of the ureteric bud and is essential for normal development of the renal papilla. Human Molecular Genetics. 20: 917-26. PMID 21138943 DOI: 10.1093/Hmg/Ddq530  0.694
2010 Reilly SM, Bhargava P, Liu S, Gangl MR, Gorgun C, Nofsinger RR, Evans RM, Qi L, Hu FB, Lee CH. Nuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deterioration. Cell Metabolism. 12: 643-53. PMID 21109196 DOI: 10.1016/J.Cmet.2010.11.007  0.808
2010 Barish GD, Yu RT, Karunasiri M, Ocampo CB, Dixon J, Benner C, Dent AL, Tangirala RK, Evans RM. Bcl-6 and NF-kappaB cistromes mediate opposing regulation of the innate immune response. Genes & Development. 24: 2760-5. PMID 21106671 DOI: 10.1101/Gad.1998010  0.317
2010 Szanto A, Balint BL, Nagy ZS, Barta E, Dezso B, Pap A, Szeles L, Poliska S, Oros M, Evans RM, Barak Y, Schwabe J, Nagy L. STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells. Immunity. 33: 699-712. PMID 21093321 DOI: 10.1016/J.Immuni.2010.11.009  0.405
2010 Alaynick WA, Way JM, Wilson SA, Benson WG, Pei L, Downes M, Yu R, Jonker JW, Holt JA, Rajpal DK, Li H, Stuart J, McPherson R, Remlinger KS, Chang CY, ... ... Evans RM, et al. ERRgamma regulates cardiac, gastric, and renal potassium homeostasis. Molecular Endocrinology (Baltimore, Md.). 24: 299-309. PMID 19965931 DOI: 10.1210/Me.2009-0114  0.713
2010 Wan Y, Evans RM. Rosiglitazone activation of PPARgamma suppresses fractalkine signaling. Journal of Molecular Endocrinology. 44: 135-42. PMID 19850645 DOI: 10.1677/Jme-09-0090  0.422
2010 Jiang YJ, Barish G, Lu B, Evans RM, Crumrine D, Schmuth M, Elias PM, Feingold KR. PPARδ activation promotes stratum corneum formation and epidermal permeability barrier development during late gestation. The Journal of Investigative Dermatology. 130: 511-9. PMID 19675577 DOI: 10.1038/jid.2009.245  0.354
2009 Alaynick WA, Way JM, Wilson SA, Benson WG, Pei L, Downes M, Yu R, Jonker JW, Holt JA, Rajpal DK, Li H, Stuart J, McPherson R, Remlinger KS, Yi-Chang C, ... ... Evans RM, et al. ERRγ Regulates Cardiac, Gastric, and Renal Potassium Homeostasis. Endocrine Reviews. 30: 931. PMID 28199598 DOI: 10.1210/Edrv.30.7.9988  0.67
2009 Evans RM. Nuclear receptors: past, present, and future. Preface. Progress in Molecular Biology and Translational Science. 87: xi-xiii. PMID 20374698 DOI: 10.1016/S1877-1173(09)87015-4  0.314
2009 Sugii S, Olson P, Sears DD, Saberi M, Atkins AR, Barish GD, Hong SH, Castro GL, Yin YQ, Nelson MC, Hsiao G, Greaves DR, Downes M, Yu RT, Olefsky JM, ... Evans RM, et al. PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization. Proceedings of the National Academy of Sciences of the United States of America. 106: 22504-9. PMID 20018750 DOI: 10.1073/Pnas.0912487106  0.571
2009 Lamia KA, Sachdeva UM, DiTacchio L, Williams EC, Alvarez JG, Egan DF, Vasquez DS, Juguilon H, Panda S, Shaw RJ, Thompson CB, Evans RM. AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation. Science (New York, N.Y.). 326: 437-40. PMID 19833968 DOI: 10.1126/Science.1172156  0.302
2009 McKenna NJ, Cooney AJ, DeMayo FJ, Downes M, Glass CK, Lanz RB, Lazar MA, Mangelsdorf DJ, Moore DD, Qin J, Steffen DL, Tsai MJ, Tsai SY, Yu R, Margolis RN, ... Evans RM, et al. Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Molecular Endocrinology (Baltimore, Md.). 23: 740-6. PMID 19423650 DOI: 10.1210/Me.2009-0135  0.348
2008 Nofsinger RR, Li P, Hong SH, Jonker JW, Barish GD, Ying H, Cheng SY, Leblanc M, Xu W, Pei L, Kang YJ, Nelson M, Downes M, Yu RT, Olefsky JM, ... ... Evans RM, et al. SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 105: 20021-6. PMID 19066220 DOI: 10.1073/Pnas.0811012105  0.817
2008 Davies BS, Waki H, Beigneux AP, Farber E, Weinstein MM, Wilpitz DC, Tai LJ, Evans RM, Fong LG, Tontonoz P, Young SG. The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by peroxisome proliferator-activated receptor-gamma. Molecular Endocrinology (Baltimore, Md.). 22: 2496-504. PMID 18787041 DOI: 10.1210/Me.2008-0146  0.4
2008 Kleiner HE, Xia X, Sonoda J, Zhang J, Pontius E, Abey J, Evans RM, Moore DD, DiGiovanni J. Effects of naturally occurring coumarins on hepatic drug-metabolizing enzymes in mice. Toxicology and Applied Pharmacology. 232: 337-50. PMID 18692084 DOI: 10.1016/J.Taap.2008.07.004  0.372
2008 Narkar VA, Downes M, Yu RT, Embler E, Wang YX, Banayo E, Mihaylova MM, Nelson MC, Zou Y, Juguilon H, Kang H, Shaw RJ, Evans RM. AMPK and PPARdelta agonists are exercise mimetics. Cell. 134: 405-15. PMID 18674809 DOI: 10.1016/J.Cell.2008.06.051  0.767
2008 Barish GD, Atkins AR, Downes M, Olson P, Chong LW, Nelson M, Zou Y, Hwang H, Kang H, Curtiss L, Evans RM, Lee CH. PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 4271-6. PMID 18337509 DOI: 10.1073/Pnas.0711875105  0.606
2008 Takata Y, Liu J, Yin F, Collins AR, Lyon CJ, Lee CH, Atkins AR, Downes M, Barish GD, Evans RM, Hsueh WA, Tangirala RK. PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 4277-82. PMID 18337495 DOI: 10.1073/pnas.0708647105  0.369
2008 Downes M, Evans RM. Staying the distance: avoiding the proteasomal trap. Cancer Cell. 13: 184-5. PMID 18328421 DOI: 10.1016/j.ccr.2008.02.014  0.389
2008 Yang CS, Ko SR, Cho BG, Shin DM, Yuk JM, Li S, Kim JM, Evans RM, Jung JS, Song DK, Jo EK. The ginsenoside metabolite compound K, a novel agonist of glucocorticoid receptor, induces tolerance to endotoxin-induced lethal shock. Journal of Cellular and Molecular Medicine. 12: 1739-53. PMID 18053081 DOI: 10.1111/j.1582-4934.2007.00181.x  0.301
2008 Sonoda J, Pei L, Evans RM. Nuclear receptors: decoding metabolic disease. Febs Letters. 582: 2-9. PMID 18023286 DOI: 10.1016/J.Febslet.2007.11.016  0.381
2008 Man MQ, Barish GD, Schmuth M, Crumrine D, Barak Y, Chang S, Jiang Y, Evans RM, Elias PM, Feingold KR. Deficiency of PPARbeta/delta in the epidermis results in defective cutaneous permeability barrier homeostasis and increased inflammation. The Journal of Investigative Dermatology. 128: 370-7. PMID 17713572 DOI: 10.1038/sj.jid.5701026  0.335
2008 Narkar VA, Downes M, Yu RT, Embler E, Wang YX, Banayo E, Mihaylova MM, Nelson MC, Zou Y, Juguilon H, Kang H, Shaw RJ, Evans RM. AMPK and PPARδ Agonists Are Exercise Mimetics (DOI:10.1016/j.cell.2008.06.051) Cell. 135: 189. DOI: 10.1016/J.Cell.2008.09.014  0.753
2007 Yang X, Lamia KA, Evans RM. Nuclear receptors, metabolism, and the circadian clock. Cold Spring Harbor Symposia On Quantitative Biology. 72: 387-94. PMID 18419296 DOI: 10.1101/Sqb.2007.72.058  0.416
2007 Wan Y, Chong LW, Evans RM. PPAR-gamma regulates osteoclastogenesis in mice. Nature Medicine. 13: 1496-503. PMID 18059282 DOI: 10.1038/Nm1672  0.355
2007 Sun G, Yu RT, Evans RM, Shi Y. Orphan nuclear receptor TLX recruits histone deacetylases to repress transcription and regulate neural stem cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 104: 15282-7. PMID 17873065 DOI: 10.1073/pnas.0704089104  0.326
2007 Ding G, Fu M, Qin Q, Lewis W, Kim HW, Fukai T, Bacanamwo M, Chen YE, Schneider MD, Mangelsdorf DJ, Evans RM, Yang Q. Cardiac peroxisome proliferator-activated receptor gamma is essential in protecting cardiomyocytes from oxidative damage. Cardiovascular Research. 76: 269-79. PMID 17678635 DOI: 10.1016/j.cardiores.2007.06.027  0.355
2007 Sonoda J, Laganière J, Mehl IR, Barish GD, Chong LW, Li X, Scheffler IE, Mock DC, Bataille AR, Robert F, Lee CH, Giguère V, Evans RM. Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense. Genes & Development. 21: 1909-20. PMID 17671090 DOI: 10.1101/Gad.1553007  0.319
2007 Alaynick WA, Kondo RP, Xie W, He W, Dufour CR, Downes M, Jonker JW, Giles W, Naviaux RK, Giguère V, Evans RM. ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart. Cell Metabolism. 6: 13-24. PMID 17618853 DOI: 10.1016/J.Cmet.2007.06.007  0.7
2007 Dufour CR, Wilson BJ, Huss JM, Kelly DP, Alaynick WA, Downes M, Evans RM, Blanchette M, Giguère V. Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma. Cell Metabolism. 5: 345-56. PMID 17488637 DOI: 10.1016/J.Cmet.2007.03.007  0.731
2007 Sonoda J, Mehl IR, Chong LW, Nofsinger RR, Evans RM. PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis. Proceedings of the National Academy of Sciences of the United States of America. 104: 5223-8. PMID 17360356 DOI: 10.1073/Pnas.0611623104  0.789
2007 Yoh SM, Cho H, Pickle L, Evans RM, Jones KA. The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export. Genes & Development. 21: 160-74. PMID 17234882 DOI: 10.1101/Gad.1503107  0.315
2006 Germain P, Chambon P, Eichele G, Evans RM, Lazar MA, Leid M, De Lera AR, Lotan R, Mangelsdorf DJ, Gronemeyer H. International Union of Pharmacology. LXIII. Retinoid X receptors. Pharmacological Reviews. 58: 760-72. PMID 17132853 DOI: 10.1124/Pr.58.4.7  0.39
2006 Germain P, Chambon P, Eichele G, Evans RM, Lazar MA, Leid M, De Lera AR, Lotan R, Mangelsdorf DJ, Gronemeyer H. International Union of Pharmacology. LX. Retinoic acid receptors. Pharmacological Reviews. 58: 712-25. PMID 17132850 DOI: 10.1124/Pr.58.4.4  0.413
2006 Yang X, Downes M, Yu RT, Bookout AL, He W, Straume M, Mangelsdorf DJ, Evans RM. Nuclear receptor expression links the circadian clock to metabolism. Cell. 126: 801-10. PMID 16923398 DOI: 10.1016/J.Cell.2006.06.050  0.402
2006 Bookout AL, Jeong Y, Downes M, Yu RT, Evans RM, Mangelsdorf DJ. Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell. 126: 789-99. PMID 16923397 DOI: 10.1016/j.cell.2006.06.049  0.392
2006 Kharroubi I, Lee CH, Hekerman P, Darville MI, Evans RM, Eizirik DL, Cnop M. BCL-6: a possible missing link for anti-inflammatory PPAR-delta signalling in pancreatic beta cells. Diabetologia. 49: 2350-8. PMID 16896941 DOI: 10.1007/s00125-006-0366-5  0.329
2006 Stedman C, Liddle C, Coulter S, Sonoda J, Alvarez JG, Evans RM, Downes M. Benefit of farnesoid X receptor inhibition in obstructive cholestasis. Proceedings of the National Academy of Sciences of the United States of America. 103: 11323-8. PMID 16844773 DOI: 10.1073/Pnas.0604772103  0.389
2006 Qi L, Heredia JE, Altarejos JY, Screaton R, Goebel N, Niessen S, Macleod IX, Liew CW, Kulkarni RN, Bain J, Newgard C, Nelson M, Evans RM, Yates J, Montminy M. TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. Science (New York, N.Y.). 312: 1763-6. PMID 16794074 DOI: 10.1126/Science.1123374  0.336
2006 Zhang CL, Zou Y, Yu RT, Gage FH, Evans RM. Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes & Development. 20: 1308-20. PMID 16702404 DOI: 10.1101/gad.1413606  0.388
2006 Zhou J, Zhai Y, Mu Y, Gong H, Uppal H, Toma D, Ren S, Evans RM, Xie W. A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway. The Journal of Biological Chemistry. 281: 15013-20. PMID 16556603 DOI: 10.1074/jbc.M511116200  0.387
2006 Barish GD, Narkar VA, Evans RM. PPAR delta: a dagger in the heart of the metabolic syndrome. The Journal of Clinical Investigation. 116: 590-7. PMID 16511591 DOI: 10.1172/JCI27955  0.334
2006 Jacobs S, Lie DC, DeCicco KL, Shi Y, DeLuca LM, Gage FH, Evans RM. Retinoic acid is required early during adult neurogenesis in the dentate gyrus. Proceedings of the National Academy of Sciences of the United States of America. 103: 3902-7. PMID 16505366 DOI: 10.1073/pnas.0511294103  0.52
2006 Lee CH, Olson P, Hevener A, Mehl I, Chong LW, Olefsky JM, Gonzalez FJ, Ham J, Kang H, Peters JM, Evans RM. PPARdelta regulates glucose metabolism and insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 103: 3444-9. PMID 16492734 DOI: 10.1073/Pnas.0511253103  0.595
2006 Sternsdorf T, Phan VT, Maunakea ML, Ocampo CB, Sohal J, Silletto A, Galimi F, Le Beau MM, Evans RM, Kogan SC. Forced retinoic acid receptor alpha homodimers prime mice for APL-like leukemia. Cancer Cell. 9: 81-94. PMID 16473276 DOI: 10.1016/J.Ccr.2005.12.030  0.312
2006 Lee CH, Kang K, Mehl IR, Nofsinger R, Alaynick WA, Chong LW, Rosenfeld JM, Evans RM. Peroxisome proliferator-activated receptor delta promotes very low-density lipoprotein-derived fatty acid catabolism in the macrophage. Proceedings of the National Academy of Sciences of the United States of America. 103: 2434-9. PMID 16467150 DOI: 10.1073/Pnas.0510815103  0.795
2006 Wang Z, Qi C, Krones A, Woodring P, Zhu X, Reddy JK, Evans RM, Rosenfeld MG, Hunter T. Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance. Cell Metabolism. 3: 111-22. PMID 16459312 DOI: 10.1016/J.Cmet.2006.01.002  0.34
2005 Zhao X, Sternsdorf T, Bolger TA, Evans RM, Yao TP. Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications. Molecular and Cellular Biology. 25: 8456-64. PMID 16166628 DOI: 10.1128/Mcb.25.19.8456-8464.2005  0.318
2005 Wolf KK, Wood SG, Hunt JA, Walton-Strong BW, Yasuda K, Lan L, Duan SX, Hao Q, Wrighton SA, Jeffery EH, Evans RM, Szakacs JG, von Moltke LL, Greenblatt DJ, Court MH, et al. Role of the nuclear receptor pregnane X receptor in acetaminophen hepatotoxicity. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 1827-36. PMID 16141365 DOI: 10.1124/dmd.105.005256  0.31
2005 Margolis RN, Evans RM, O'Malley BW. The Nuclear Receptor Signaling Atlas: development of a functional atlas of nuclear receptors. Molecular Endocrinology (Baltimore, Md.). 19: 2433-6. PMID 16051673 DOI: 10.1210/me.2004-0461  0.335
2005 Barish GD, Downes M, Alaynick WA, Yu RT, Ocampo CB, Bookout AL, Mangelsdorf DJ, Evans RM. A Nuclear Receptor Atlas: macrophage activation. Molecular Endocrinology (Baltimore, Md.). 19: 2466-77. PMID 16051664 DOI: 10.1210/Me.2004-0529  0.743
2005 Fu M, Sun T, Bookout AL, Downes M, Yu RT, Evans RM, Mangelsdorf DJ. A Nuclear Receptor Atlas: 3T3-L1 adipogenesis. Molecular Endocrinology (Baltimore, Md.). 19: 2437-50. PMID 16051663 DOI: 10.1210/me.2004-0539  0.418
2005 Evans RM. The nuclear receptor superfamily: a rosetta stone for physiology. Molecular Endocrinology (Baltimore, Md.). 19: 1429-38. PMID 15914712 DOI: 10.1210/me.2005-0046  0.413
2005 Noreault TL, Jacobs JM, Nichols RC, Trask HW, Wrighton SA, Sinclair PR, Evans RM, Sinclair JF. Arsenite decreases CYP3A23 induction in cultured rat hepatocytes by transcriptional and translational mechanisms. Toxicology and Applied Pharmacology. 209: 174-82. PMID 15907335 DOI: 10.1016/j.taap.2005.04.008  0.303
2005 Noreault TL, Kostrubsky VE, Wood SG, Nichols RC, Strom SC, Trask HW, Wrighton SA, Evans RM, Jacobs JM, Sinclair PR, Sinclair JF. Arsenite decreases CYP3A4 and RXRalpha in primary human hepatocytes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 993-1003. PMID 15833926 DOI: 10.1124/dmd.105.003954  0.379
2005 Pavri R, Lewis B, Kim TK, Dilworth FJ, Erdjument-Bromage H, Tempst P, de Murcia G, Evans R, Chambon P, Reinberg D. PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator. Molecular Cell. 18: 83-96. PMID 15808511 DOI: 10.1016/J.Molcel.2005.02.034  0.386
2005 Stedman CA, Liddle C, Coulter SA, Sonoda J, Alvarez JG, Moore DD, Evans RM, Downes M. Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury. Proceedings of the National Academy of Sciences of the United States of America. 102: 2063-8. PMID 15684063 DOI: 10.1073/Pnas.0409794102  0.398
2005 Sonoda J, Chong LW, Downes M, Barish GD, Coulter S, Liddle C, Lee CH, Evans RM. Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites. Proceedings of the National Academy of Sciences of the United States of America. 102: 2198-203. PMID 15671183 DOI: 10.1073/Pnas.0409481102  0.383
2005 Galimi F, Saez E, Gall J, Hoong N, Cho G, Evans RM, Verma IM. Development of ecdysone-regulated lentiviral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 142-8. PMID 15585415 DOI: 10.1016/J.Ymthe.2004.08.021  0.325
2004 Shalom-Barak T, Nicholas JM, Wang Y, Zhang X, Ong ES, Young TH, Gendler SJ, Evans RM, Barak Y. Peroxisome proliferator-activated receptor gamma controls Muc1 transcription in trophoblasts. Molecular and Cellular Biology. 24: 10661-9. PMID 15572671 DOI: 10.1128/MCB.24.24.10661-10669.2004  0.428
2004 Barish GD, Evans RM. A nuclear strike against Listeria--the evolving life of LXR. Cell. 119: 149-51. PMID 15479632 DOI: 10.1016/j.cell.2004.10.003  0.365
2004 Cheng L, Ding G, Qin Q, Huang Y, Lewis W, He N, Evans RM, Schneider MD, Brako FA, Xiao Y, Chen YE, Yang Q. Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy. Nature Medicine. 10: 1245-50. PMID 15475963 DOI: 10.1038/nm1116  0.353
2004 Evans R. A transcriptional basis for physiology. Nature Medicine. 10: 1022-1026. PMID 15459694 DOI: 10.1038/Nm1004-1022  0.31
2004 Zhang J, Huang W, Qatanani M, Evans RM, Moore DD. The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity. The Journal of Biological Chemistry. 279: 49517-22. PMID 15358766 DOI: 10.1074/Jbc.M409041200  0.418
2004 Wang YX, Zhang CL, Yu RT, Cho HK, Nelson MC, Bayuga-Ocampo CR, Ham J, Kang H, Evans RM. Regulation of muscle fiber type and running endurance by PPARdelta. Plos Biology. 2: e294. PMID 15328533 DOI: 10.1371/journal.pbio.0020294  0.316
2004 Barish GD, Evans RM. PPARs and LXRs: atherosclerosis goes nuclear. Trends in Endocrinology and Metabolism: Tem. 15: 158-65. PMID 15109614 DOI: 10.1016/j.tem.2004.03.003  0.403
2004 Koo SH, Satoh H, Herzig S, Lee CH, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M. PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nature Medicine. 10: 530-4. PMID 15107844 DOI: 10.1038/Nm1044  0.346
2004 Evans RM, Barish GD, Wang YX. PPARs and the complex journey to obesity. Nature Medicine. 10: 355-61. PMID 15057233 DOI: 10.1038/nm1025  0.345
2004 Saez E, Rosenfeld J, Livolsi A, Olson P, Lombardo E, Nelson M, Banayo E, Cardiff RD, Izpisua-Belmonte JC, Evans RM. PPAR gamma signaling exacerbates mammary gland tumor development. Genes & Development. 18: 528-40. PMID 15037548 DOI: 10.1101/Gad.1167804  0.569
2004 Tsai CC, Kao HY, Mitzutani A, Banayo E, Rajan H, McKeown M, Evans RM. Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors. Proceedings of the National Academy of Sciences of the United States of America. 101: 4047-52. PMID 15016912 DOI: 10.1073/pnas.0400615101  0.368
2004 Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD. Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. The Journal of Biological Chemistry. 279: 22250-7. PMID 15004017 DOI: 10.1074/Jbc.M314111200  0.355
2004 Saini SP, Sonoda J, Xu L, Toma D, Uppal H, Mu Y, Ren S, Moore DD, Evans RM, Xie W. A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification. Molecular Pharmacology. 65: 292-300. PMID 14742670 DOI: 10.1124/Mol.65.2.292  0.418
2004 Xu W, Cho H, Kadam S, Banayo EM, Anderson S, Yates JR, Emerson BM, Evans RM. A methylation-mediator complex in hormone signaling. Genes & Development. 18: 144-56. PMID 14729568 DOI: 10.1101/Gad.1141704  0.369
2004 Kogan SC, Phan VT, Sternsdorf T, Maunakea ML, Sohal J, Silletto A, Galimi F, Evans RM. Homodimerization of Retinoic Acid Receptor alpha through its Fusion Partners Underlies Pathogenesis of Acute Promyelocytic Leukemia. Blood. 104: 546-546. DOI: 10.1182/Blood.V104.11.546.546  0.34
2003 He W, Barak Y, Hevener A, Olson P, Liao D, Le J, Nelson M, Ong E, Olefsky JM, Evans RM. Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle. Proceedings of the National Academy of Sciences of the United States of America. 100: 15712-7. PMID 14660788 DOI: 10.1073/Pnas.2536828100  0.573
2003 Natarajan C, Muthian G, Barak Y, Evans RM, Bright JJ. Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 171: 5743-50. PMID 14634082 DOI: 10.4049/Jimmunol.171.11.5743  0.358
2003 Xu W, Cho H, Evans RM. Acetylation and methylation in nuclear receptor gene activation. Methods in Enzymology. 364: 205-23. PMID 14631847 DOI: 10.1016/S0076-6879(03)64012-7  0.391
2003 Hevener AL, He W, Barak Y, Le J, Bandyopadhyay G, Olson P, Wilkes J, Evans RM, Olefsky J. Muscle-specific Pparg deletion causes insulin resistance. Nature Medicine. 9: 1491-7. PMID 14625542 DOI: 10.1038/Nm956  0.538
2003 Lee CH, Chawla A, Urbiztondo N, Liao D, Boisvert WA, Evans RM, Curtiss LK. Transcriptional repression of atherogenic inflammation: modulation by PPARdelta. Science (New York, N.Y.). 302: 453-7. PMID 12970571 DOI: 10.1126/science.1087344  0.351
2003 Saez E, Olson P, Evans RM. Genetic deficiency in Pparg does not alter development of experimental prostate cancer. Nature Medicine. 9: 1265-6. PMID 12960963 DOI: 10.1038/Nm928  0.522
2003 Nicolaou KC, Evans RM, Roecker AJ, Hughes R, Downes M, Pfefferkorn JA. Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries. Organic & Biomolecular Chemistry. 1: 908-20. PMID 12929628 DOI: 10.1039/B300525A  0.341
2003 Lee CH, Olson P, Evans RM. Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. Endocrinology. 144: 2201-7. PMID 12746275 DOI: 10.1210/En.2003-0288  0.625
2003 Downes M, Verdecia MA, Roecker AJ, Hughes R, Hogenesch JB, Kast-Woelbern HR, Bowman ME, Ferrer JL, Anisfeld AM, Edwards PA, Rosenfeld JM, Alvarez JG, Noel JP, Nicolaou KC, Evans RM. A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR. Molecular Cell. 11: 1079-92. PMID 12718892 DOI: 10.1016/S1097-2765(03)00104-7  0.385
2003 Wang YX, Lee CH, Tiep S, Yu RT, Ham J, Kang H, Evans RM. Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. Cell. 113: 159-70. PMID 12705865 DOI: 10.1016/S0092-8674(03)00269-1  0.351
2003 Rosenfeld JM, Vargas R, Xie W, Evans RM. Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor. Molecular Endocrinology (Baltimore, Md.). 17: 1268-82. PMID 12663745 DOI: 10.1210/me.2002-0421  0.396
2003 Gearhart MD, Holmbeck SM, Evans RM, Dyson HJ, Wright PE. Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition. Journal of Molecular Biology. 327: 819-32. PMID 12654265 DOI: 10.1016/S0022-2836(03)00183-9  0.332
2003 Xie W, Yeuh MF, Radominska-Pandya A, Saini SP, Negishi Y, Bottroff BS, Cabrera GY, Tukey RH, Evans RM. Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor. Proceedings of the National Academy of Sciences of the United States of America. 100: 4150-5. PMID 12644700 DOI: 10.1073/Pnas.0438010100  0.434
2003 Sonoda J, Rosenfeld JM, Xu L, Evans RM, Xie W. A nuclear receptor-mediated xenobiotic response and its implication in drug metabolism and host protection. Current Drug Metabolism. 4: 59-72. PMID 12570746 DOI: 10.2174/1389200033336739  0.331
2003 Miles PD, Barak Y, Evans RM, Olefsky JM. Effect of heterozygous PPARgamma deficiency and TZD treatment on insulin resistance associated with age and high-fat feeding. American Journal of Physiology. Endocrinology and Metabolism. 284: E618-26. PMID 12556354 DOI: 10.1152/Ajpendo.00312.2002  0.336
2003 Chawla A, Lee CH, Barak Y, He W, Rosenfeld J, Liao D, Han J, Kang H, Evans RM. PPARdelta is a very low-density lipoprotein sensor in macrophages. Proceedings of the National Academy of Sciences of the United States of America. 100: 1268-73. PMID 12540828 DOI: 10.1073/Pnas.0337331100  0.396
2003 Kao HY, Han CC, Komar AA, Evans RM. Co-repressor release but not ligand binding is a prerequisite for transcription activation by human retinoid acid receptor alpha ligand-binding domain. The Journal of Biological Chemistry. 278: 7366-73. PMID 12468549 DOI: 10.1074/Jbc.M207569200  0.401
2003 Sonoda J, Evans RM. Biological function and mode of action of nuclear xenobiotic receptors Pure and Applied Chemistry. 75: 1733-1742. DOI: 10.1351/Pac200375111733  0.381
2002 Sonoda J, Xie W, Rosenfeld JM, Barwick JL, Guzelian PS, Evans RM. Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR). Proceedings of the National Academy of Sciences of the United States of America. 99: 13801-6. PMID 12370413 DOI: 10.1073/Pnas.212494599  0.386
2002 Lee CH, Evans RM. Peroxisome proliferator-activated receptor-gamma in macrophage lipid homeostasis. Trends in Endocrinology and Metabolism: Tem. 13: 331-5. PMID 12217489 DOI: 10.1016/S1043-2760(02)00668-9  0.408
2002 Makishima M, Lu TT, Xie W, Whitfield GK, Domoto H, Evans RM, Haussler MR, Mangelsdorf DJ. Vitamin D receptor as an intestinal bile acid sensor. Science (New York, N.Y.). 296: 1313-6. PMID 12016314 DOI: 10.1126/Science.1070477  0.328
2002 Xie W, Evans RM. Pharmaceutical use of mouse models humanized for the xenobiotic receptor. Drug Discovery Today. 7: 509-15. PMID 11983567 DOI: 10.1016/S1359-6446(02)02251-1  0.331
2002 Pitman JL, Tsai CC, Edeen PT, Finley KD, Evans RM, McKeown M. DSF nuclear receptor acts as a repressor in culture and in vivo. Developmental Biology. 245: 315-28. PMID 11977984 DOI: 10.1006/dbio.2002.0648  0.367
2002 Shi Y, Hon M, Evans RM. The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. 99: 2613-8. PMID 11867749 DOI: 10.1073/pnas.052707099  0.454
2002 Demarest SJ, Martinez-Yamout M, Chung J, Chen H, Xu W, Dyson HJ, Evans RM, Wright PE. Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators. Nature. 415: 549-53. PMID 11823864 DOI: 10.1038/415549A  0.411
2002 Love JD, Gooch JT, Benko S, Li C, Nagy L, Chatterjee VK, Evans RM, Schwabe JW. The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12. The Journal of Biological Chemistry. 277: 11385-91. PMID 11782480 DOI: 10.1074/Jbc.M110869200  0.366
2002 Barak Y, Liao D, He W, Ong ES, Nelson MC, Olefsky JM, Boland R, Evans RM. Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America. 99: 303-8. PMID 11756685 DOI: 10.1073/Pnas.012610299  0.396
2001 Chawla A, Repa JJ, Evans RM, Mangelsdorf DJ. Nuclear receptors and lipid physiology: opening the X-files. Science (New York, N.Y.). 294: 1866-70. PMID 11729302 DOI: 10.1126/science.294.5548.1866  0.368
2001 Lin RJ, Sternsdorf T, Tini M, Evans RM. Transcriptional regulation in acute promyelocytic leukemia. Oncogene. 20: 7204-15. PMID 11704848 DOI: 10.1038/Sj.Onc.1204853  0.576
2001 Xu W, Chen H, Du K, Asahara H, Tini M, Emerson BM, Montminy M, Evans RM. A transcriptional switch mediated by cofactor methylation. Science (New York, N.Y.). 294: 2507-11. PMID 11701890 DOI: 10.1126/Science.1065961  0.319
2001 Misner DL, Jacobs S, Shimizu Y, de Urquiza AM, Solomin L, Perlmann T, De Luca LM, Stevens CF, Evans RM. Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. 98: 11714-9. PMID 11553775 DOI: 10.1073/pnas.191369798  0.5
2001 Xie W, Evans RM. Orphan nuclear receptors: the exotics of xenobiotics. The Journal of Biological Chemistry. 276: 37739-42. PMID 11459851 DOI: 10.1074/jbc.R100033200  0.382
2001 Shi Y, Downes M, Xie W, Kao HY, Ordentlich P, Tsai CC, Hon M, Evans RM. Sharp, an inducible cofactor that integrates nuclear receptor repression and activation. Genes & Development. 15: 1140-51. PMID 11331609 DOI: 10.1101/Gad.871201  0.433
2001 Dressel U, Bailey PJ, Wang SC, Downes M, Evans RM, Muscat GE. A dynamic role for HDAC7 in MEF2-mediated muscle differentiation. The Journal of Biological Chemistry. 276: 17007-13. PMID 11279209 DOI: 10.1074/jbc.M101508200  0.312
2001 Ghbeish N, Tsai CC, Schubiger M, Zhou JY, Evans RM, McKeown M. The dual role of ultraspiracle, the Drosophila retinoid X receptor, in the ecdysone response. Proceedings of the National Academy of Sciences of the United States of America. 98: 3867-72. PMID 11274407 DOI: 10.1073/pnas.061437798  0.411
2001 Xie W, Radominska-Pandya A, Shi Y, Simon CM, Nelson MC, Ong ES, Waxman DJ, Evans RM. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proceedings of the National Academy of Sciences of the United States of America. 98: 3375-80. PMID 11248086 DOI: 10.1073/Pnas.051014398  0.393
2001 Ordentlich P, Downes M, Evans RM. Corepressors and nuclear hormone receptor function. Current Topics in Microbiology and Immunology. 254: 101-16. PMID 11190569 DOI: 10.1007/978-3-662-10595-5_5  0.347
2001 Chawla A, Boisvert WA, Lee CH, Laffitte BA, Barak Y, Joseph SB, Liao D, Nagy L, Edwards PA, Curtiss LK, Evans RM, Tontonoz P. A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Molecular Cell. 7: 161-71. PMID 11172721 DOI: 10.1016/S1097-2765(01)00164-2  0.333
2001 Clayton GM, Peak-Chew SY, Evans RM, Schwabe JW. The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation. Proceedings of the National Academy of Sciences of the United States of America. 98: 1549-54. PMID 11171988 DOI: 10.1073/pnas.041611298  0.382
2001 Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM. PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nature Medicine. 7: 48-52. PMID 11135615 DOI: 10.1038/83336  0.377
2000 Xie W, Barwick JL, Simon CM, Pierce AM, Safe S, Blumberg B, Guzelian PS, Evans RM. Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR. Genes & Development. 14: 3014-23. PMID 11114890 DOI: 10.1101/Gad.846800  0.651
2000 Saez E, Nelson MC, Eshelman B, Banayo E, Koder A, Cho GJ, Evans RM. Identification of ligands and coligands for the ecdysone-regulated gene switch. Proceedings of the National Academy of Sciences of the United States of America. 97: 14512-7. PMID 11114195 DOI: 10.1073/Pnas.260499497  0.377
2000 Chawla A, Saez E, Evans RM. "Don't know much bile-ology". Cell. 103: 1-4. PMID 11051540 DOI: 10.1016/S0092-8674(00)00097-0  0.356
2000 Doucas V, Shi Y, Miyamoto S, West A, Verma I, Evans RM. Cytoplasmic catalytic subunit of protein kinase A mediates cross-repression by NF-kappa B and the glucocorticoid receptor. Proceedings of the National Academy of Sciences of the United States of America. 97: 11893-8. PMID 11027313 DOI: 10.1073/Pnas.220413297  0.373
2000 Lee H, Shi W, Tontonoz P, Wang S, Subbanagounder G, Hedrick CC, Hama S, Borromeo C, Evans RM, Berliner JA, Nagy L. Role for peroxisome proliferator-activated receptor alpha in oxidized phospholipid-induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells. Circulation Research. 87: 516-21. PMID 10988245 DOI: 10.1161/01.Res.87.6.516  0.354
2000 Downes M, Ordentlich P, Kao HY, Alvarez JG, Evans RM. Identification of a nuclear domain with deacetylase activity. Proceedings of the National Academy of Sciences of the United States of America. 97: 10330-5. PMID 10984530 DOI: 10.1073/Pnas.97.19.10330  0.35
2000 Xie W, Barwick JL, Downes M, Blumberg B, Simon CM, Nelson MC, Neuschwander-Tetri BA, Brunt EM, Guzelian PS, Evans RM. Humanized xenobiotic response in mice expressing nuclear receptor SXR. Nature. 406: 435-9. PMID 10935643 DOI: 10.1038/35019116  0.638
2000 Lin RJ, Evans RM. Acquisition of oncogenic potential by RAR chimeras in acute promyelocytic leukemia through formation of homodimers. Molecular Cell. 5: 821-30. PMID 10882118 DOI: 10.1016/S1097-2765(00)80322-6  0.572
2000 Takada I, Yu RT, Xu HE, Lambert MH, Montana VG, Kliewer SA, Evans RM, Umesono K. Alteration of a single amino acid in peroxisome proliferator-activated receptor-alpha (PPAR alpha) generates a PPAR delta phenotype. Molecular Endocrinology (Baltimore, Md.). 14: 733-40. PMID 10809235 DOI: 10.1210/Mend.14.5.0456  0.361
2000 Yu RT, Chiang MY, Tanabe T, Kobayashi M, Yasuda K, Evans RM, Umesono K. The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision. Proceedings of the National Academy of Sciences of the United States of America. 97: 2621-5. PMID 10706625 DOI: 10.1073/pnas.050566897  0.356
2000 Miles PD, Barak Y, He W, Evans RM, Olefsky JM. Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency. The Journal of Clinical Investigation. 105: 287-92. PMID 10675354 DOI: 10.1172/Jci8538  0.309
2000 Kao HY, Downes M, Ordentlich P, Evans RM. Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression. Genes & Development. 14: 55-66. PMID 10640276 DOI: 10.1101/Gad.14.1.55  0.302
1999 Nagy L, Kao HY, Love JD, Li C, Banayo E, Gooch JT, Krishna V, Chatterjee K, Evans RM, Schwabe JW. Mechanism of corepressor binding and release from nuclear hormone receptors. Genes & Development. 13: 3209-16. PMID 10617570 DOI: 10.1101/Gad.13.24.3209  0.407
1999 Xie W, Hong H, Yang NN, Lin RJ, Simon CM, Stallcup MR, Evans RM. Constitutive activation of transcription and binding of coactivator by estrogen-related receptors 1 and 2. Molecular Endocrinology (Baltimore, Md.). 13: 2151-62. PMID 10598588 DOI: 10.1210/Mend.13.12.0381  0.62
1999 Asahara H, Dutta S, Kao HY, Evans RM, Montminy M. Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner. Molecular and Cellular Biology. 19: 8219-25. PMID 10567547 DOI: 10.1128/Mcb.19.12.8219  0.348
1999 Barak Y, Nelson MC, Ong ES, Jones YZ, Ruiz-Lozano P, Chien KR, Koder A, Evans RM. PPAR gamma is required for placental, cardiac, and adipose tissue development. Molecular Cell. 4: 585-95. PMID 10549290 DOI: 10.1016/S1097-2765(00)80209-9  0.339
1999 Murphy M, Ahn J, Walker KK, Hoffman WH, Evans RM, Levine AJ, George DL. Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes & Development. 13: 2490-501. PMID 10521394 DOI: 10.1101/Gad.13.19.2490  0.314
1999 Tsukui T, Capdevila J, Tamura K, Ruiz-Lozano P, Rodriguez-Esteban C, Yonei-Tamura S, Magallón J, Chandraratna RA, Chien K, Blumberg B, Evans RM, Belmonte JC. Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1. Proceedings of the National Academy of Sciences of the United States of America. 96: 11376-81. PMID 10500184 DOI: 10.1073/Pnas.96.20.11376  0.552
1999 Chen H, Lin RJ, Xie W, Wilpitz D, Evans RM. Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase. Cell. 98: 675-86. PMID 10490106 DOI: 10.1016/S0092-8674(00)80054-9  0.59
1999 Tsai CC, Kao HY, Yao TP, McKeown M, Evans RM. SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development. Molecular Cell. 4: 175-86. PMID 10488333 DOI: 10.1016/S1097-2765(00)80365-2  0.42
1999 Egan DA, Evans RM. Target acquisition and acute promyelocytic leukemia. The Journal of Clinical Investigation. 103: 1367-8. PMID 10330417 DOI: 10.1172/JCI7118  0.362
1999 Lin RJ, Egan DA, Evans RM. Molecular genetics of acute promyelocytic leukemia. Trends in Genetics : Tig. 15: 179-84. PMID 10322484 DOI: 10.1016/S0168-9525(99)01710-2  0.563
1999 Auwerx J, Baulieu E, Beato M, Becker-Andre M, Burbach PH, Camerino G, Chambon P, Cooney A, Dejean A, Dreyer C, Evans RM, Gannon F, Giguere V, Gronemeyer H, Gustafsson JA, et al. A unified nomenclature system for the nuclear receptor superfamily Cell. 97: 161-163. PMID 10219237 DOI: 10.1016/S0092-8674(00)80726-6  0.38
1999 Ordentlich P, Downes M, Xie W, Genin A, Spinner NB, Evans RM. Unique forms of human and mouse nuclear receptor corepressor SMRT. Proceedings of the National Academy of Sciences of the United States of America. 96: 2639-44. PMID 10077563 DOI: 10.1073/Pnas.96.6.2639  0.417
1999 Doucas V, Evans RM. Human T-cell leukemia retrovirus-Tax protein is a repressor of nuclear receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. 96: 2633-8. PMID 10077562 DOI: 10.1073/PNAS.96.6.2633  0.399
1999 Doucas V, Tini M, Egan DA, Evans RM. Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling Proceedings of the National Academy of Sciences of the United States of America. 96: 2627-2632. PMID 10077561 DOI: 10.1073/pnas.96.6.2627  0.357
1999 Chakravarti D, Ogryzko V, Kao HY, Nash A, Chen H, Nakatani Y, Evans RM. A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity. Cell. 96: 393-403. PMID 10025405 DOI: 10.1016/S0092-8674(00)80552-8  0.318
1998 Lin RJ, Kao HY, Ordentlich P, Evans RM. The transcriptional basis of steroid physiology. Cold Spring Harbor Symposia On Quantitative Biology. 63: 577-85. PMID 10384323 DOI: 10.1101/Sqb.1998.63.577  0.544
1998 Blumberg B, Sabbagh W, Juguilon H, Bolado J, Meter CMV, Ong ES, Evans RM. SXR, a novel steroid and xenobiotic-sensing nuclear receptor. Genes & Development. 12: 3195-3205. PMID 9784494 DOI: 10.1101/Gad.12.20.3195  0.644
1998 Blumberg B, Evans RM. Orphan nuclear receptors--new ligands and new possibilities. Genes & Development. 12: 3149-55. PMID 9784489 DOI: 10.1101/Gad.12.20.3149  0.633
1998 Forman BM, Tzameli I, Choi HS, Chen J, Simha D, Seol W, Evans RM, Moore DD. Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta. Nature. 395: 612-5. PMID 9783588 DOI: 10.1038/26996  0.371
1998 Dhordain P, Lin RJ, Quief S, Lantoine D, Kerckaert JP, Evans RM, Albagli O. The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression. Nucleic Acids Research. 26: 4645-51. PMID 9753732 DOI: 10.1093/Nar/26.20.4645  0.548
1998 Saez E, Tontonoz P, Nelson MC, Alvarez JG, Ming UT, Baird SM, Thomazy VA, Evans RM. Activators of the nuclear receptor PPARgamma enhance colon polyp formation. Nature Medicine. 4: 1058-61. PMID 9734400 DOI: 10.1038/2042  0.378
1998 Ryan AK, Blumberg B, Rodriguez-Esteban C, Yonei-Tamura S, Tamura K, Tsukui T, de la Peña J, Sabbagh W, Greenwald J, Choe S, Norris DP, Robertson EJ, Evans RM, Rosenfeld MG, Izpisúa Belmonte JC. Pitx2 determines left-right asymmetry of internal organs in vertebrates. Nature. 394: 545-51. PMID 9707115 DOI: 10.1038/29004  0.563
1998 Kao HY, Ordentlich P, Koyano-Nakagawa N, Tang Z, Downes M, Kintner CR, Evans RM, Kadesch T. A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. Genes & Development. 12: 2269-77. PMID 9694793 DOI: 10.1101/Gad.12.15.2269  0.349
1998 Mueller E, Sarraf P, Tontonoz P, Evans RM, Martin KJ, Zhang M, Fletcher C, Singer S, Spiegelman BM. Terminal differentiation of human breast cancer through PPAR gamma. Molecular Cell. 1: 465-70. PMID 9660931 DOI: 10.1016/S1097-2765(00)80047-7  0.301
1998 Blanco JC, Minucci S, Lu J, Yang XJ, Walker KK, Chen H, Evans RM, Nakatani Y, Ozato K. The histone acetylase PCAF is a nuclear receptor coactivator. Genes & Development. 12: 1638-51. PMID 9620851 DOI: 10.1101/Gad.12.11.1638  0.421
1998 Blumberg B, Kang H, Bolado J, Chen H, Craig AG, Moreno TA, Umesono K, Perlmann T, De Robertis EM, Evans RM. BXR, an embryonic orphan nuclear receptor activated by a novel class of endogenous benzoate metabolites. Genes & Development. 12: 1269-77. PMID 9573044 DOI: 10.1101/Gad.12.9.1269  0.723
1998 Tontonoz P, Nagy L, Alvarez JG, Thomazy VA, Evans RM. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell. 93: 241-52. PMID 9568716 DOI: 10.1016/S0092-8674(00)81575-5  0.405
1998 Nagy L, Tontonoz P, Alvarez JG, Chen H, Evans RM. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell. 93: 229-40. PMID 9568715 DOI: 10.1016/S0092-8674(00)81574-3  0.391
1998 LaMorte VJ, Dyck JA, Ochs RL, Evans RM. Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body. Proceedings of the National Academy of Sciences of the United States of America. 95: 4991-6. PMID 9560216 DOI: 10.1073/PNAS.95.9.4991  0.317
1998 Lin RJ, Nagy L, Inoue S, Shao W, Miller WH, Evans RM. Role of the histone deacetylase complex in acute promyelocytic leukaemia. Nature. 391: 811-4. PMID 9486654 DOI: 10.1038/35895  0.566
1997 Dhordain P, Albagli O, Lin RJ, Ansieau S, Quief S, Leutz A, Kerckaert JP, Evans RM, Leprince D. Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein. Proceedings of the National Academy of Sciences of the United States of America. 94: 10762-7. PMID 9380707 DOI: 10.1073/Pnas.94.20.10762  0.578
1997 Forman BM, Ruan B, Chen J, Schroepfer GJ, Evans RM. The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism. Proceedings of the National Academy of Sciences of the United States of America. 94: 10588-93. PMID 9380679 DOI: 10.1073/Pnas.94.20.10588  0.378
1997 Saez E, No D, West A, Evans RM. Inducible gene expression in mammalian cells and transgenic mice Current Opinion in Biotechnology. 8: 608-616. PMID 9353233 DOI: 10.1016/S0958-1669(97)80037-7  0.357
1997 Süsens U, Aguiluz JB, Evans RM, Borgmeyer U. The germ cell nuclear factor mGCNF is expressed in the developing nervous system. Developmental Neuroscience. 19: 410-20. PMID 9323461 DOI: 10.1159/000111238  0.405
1997 Chen H, Lin RJ, Schiltz RL, Chakravarti D, Nash A, Nagy L, Privalsky ML, Nakatani Y, Evans RM. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell. 90: 569-80. PMID 9267036 DOI: 10.1016/S0092-8674(00)80516-4  0.588
1997 Perlmann T, Evans RM. Nuclear receptors in Sicily: all in the famiglia. Cell. 90: 391-7. PMID 9267019 DOI: 10.1016/S0092-8674(00)80498-5  0.412
1997 Sem DS, Casimiro DR, Kliewer SA, Provencal J, Evans RM, Wright PE. NMR spectroscopic studies of the DNA-binding domain of the monomer-binding nuclear orphan receptor, human estrogen related receptor-2. The carboxyl-terminal extension to the zinc-finger region is unstructured in the free form of the protein. The Journal of Biological Chemistry. 272: 18038-43. PMID 9218433 DOI: 10.1074/Jbc.272.29.18038  0.371
1997 Lee RY, Luo J, Evans RM, Giguere V, Sucov HM. Compartment-selective sensitivity of cardiovascular morphogenesis to combinations of retinoic acid receptor gene mutations Circulation Research. 80: 757-764. PMID 9168777 DOI: 10.1161/01.Res.80.6.757  0.343
1997 Nagy L, Kao HY, Chakravarti D, Lin RJ, Hassig CA, Ayer DE, Schreiber SL, Evans RM. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell. 89: 373-80. PMID 9150137 DOI: 10.1016/S0092-8674(00)80218-4  0.606
1997 Li C, Schwabe JW, Banayo E, Evans RM. Coexpression of nuclear receptor partners increases their solubility and biological activities. Proceedings of the National Academy of Sciences of the United States of America. 94: 2278-83. PMID 9122185 DOI: 10.1073/PNAS.94.6.2278  0.406
1997 Forman BM, Chen J, Evans RM. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta. Proceedings of the National Academy of Sciences of the United States of America. 94: 4312-7. PMID 9113986 DOI: 10.1073/PNAS.94.9.4312  0.394
1997 Forman BM, Chen J, Evans RM. The peroxisome proliferator-activated receptors: ligands and activators. Annals of the New York Academy of Sciences. 804: 266-75. PMID 8993549 DOI: 10.1111/j.1749-6632.1996.tb18621.x  0.353
1997 Tontonoz P, Singer S, Forman BM, Sarraf P, Fletcher JA, Fletcher CD, Brun RP, Mueller E, Altiok S, Oppenheim H, Evans RM, Spiegelman BM. Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor. Proceedings of the National Academy of Sciences of the United States of America. 94: 237-41. PMID 8990192 DOI: 10.1073/Pnas.94.1.237  0.392
1996 Perlmann T, Umesono K, Rangarajan PN, Forman BM, Evans RM. Two distinct dimerization interfaces differentially modulate target gene specificity of nuclear hormone receptors. Molecular Endocrinology (Baltimore, Md.). 10: 958-66. PMID 8843412 DOI: 10.1210/mend.10.8.8843412  0.391
1996 Lala DS, Mukherjee R, Schulman IG, Koch SS, Dardashti LJ, Nadzan AM, Croston GE, Evans RM, Heyman RA. Activation of specific RXR heterodimers by an antagonist of RXR homodimers. Nature. 383: 450-3. PMID 8837780 DOI: 10.1038/383450a0  0.448
1996 Chakravarti D, LaMorte VJ, Nelson MC, Nakajima T, Schulman IG, Juguilon H, Montminy M, Evans RM. Role of CBP/P300 in nuclear receptor signalling. Nature. 383: 99-103. PMID 8779723 DOI: 10.1038/383099A0  0.421
1996 Early E, Moore MA, Kakizuka A, Nason-Burchenal K, Martin P, Evans RM, Dmitrovsky E. Transgenic expression of PML/RARalpha impairs myelopoiesis. Proceedings of the National Academy of Sciences of the United States of America. 93: 7900-4. PMID 8755574 DOI: 10.1073/Pnas.93.15.7900  0.328
1996 Chen JD, Umesono K, Evans RM. SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers. Proceedings of the National Academy of Sciences of the United States of America. 93: 7567-71. PMID 8755515 DOI: 10.1073/pnas.93.15.7567  0.447
1996 Luo J, Sucov HM, Bader JA, Evans RM, Giguère V. Compound mutants for retinoic acid receptor (RAR) β and RARα1 reveal developmental functions for multiple RARβ isoforms Mechanisms of Development. 55: 33-44. PMID 8734497 DOI: 10.1016/0925-4773(95)00488-2  0.303
1996 Göttlicher M, Heck S, Doucas V, Wade E, Kullmann M, Cato ACB, Evans RM, Herrlich P. Interaction of the Ubc9 human homologue with c-Jun and with the glucocorticoid receptor Steroids. 61: 257-262. PMID 8733011 DOI: 10.1016/0039-128X(96)00032-3  0.355
1996 Schulman IG, Juguilon H, Evans RM. Activation and repression by nuclear hormone receptors: hormone modulates an equilibrium between active and repressive states. Molecular and Cellular Biology. 16: 3807-13. PMID 8668198 DOI: 10.1128/MCB.16.7.3807  0.402
1996 Achkar CC, Derguini F, Blumberg B, Langston A, Levin AA, Speck J, Evans RM, Bolado J, Nakanishi K, Buck J, Gudas LJ. 4-Oxoretinol, a new natural ligand and transactivator of the retinoic acid receptors. Proceedings of the National Academy of Sciences of the United States of America. 93: 4879-84. PMID 8643497 DOI: 10.1073/Pnas.93.10.4879  0.608
1996 Blumberg B, Bolado J, Derguini F, Craig AG, Moreno TA, Chakravarti D, Heyman RA, Buck J, Evans RM. Novel retinoic acid receptor ligands in Xenopus embryos. Proceedings of the National Academy of Sciences of the United States of America. 93: 4873-8. PMID 8643496 DOI: 10.1073/Pnas.93.10.4873  0.621
1996 No D, Yao TP, Evans RM. Ecdysone-inducible gene expression in mammalian cells and transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 3346-51. PMID 8622939 DOI: 10.1073/Pnas.93.8.3346  0.429
1996 Brun RP, Tontonoz P, Forman BM, Ellis R, Chen J, Evans RM, Spiegelman BM. Differential activation of adipogenesis by multiple PPAR isoforms. Genes & Development. 10: 974-84. PMID 8608944 DOI: 10.1101/Gad.10.8.974  0.432
1996 Mangelsdorf DJ, Evans RM. The RXR heterodimers and orphan receptors. Cell. 83: 841-50. PMID 8521508 DOI: 10.1016/0092-8674(95)90200-7  0.372
1996 Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM. 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell. 83: 803-12. PMID 8521497 DOI: 10.1016/0092-8674(95)90193-0  0.416
1996 Sucov HM, LaMorte V, Luo J, Giguere V, Evans RM. The pharmaco-genetics of congenital cardiac defects in retinoic acid receptor deficient mouse embryos Journal of the American College of Cardiology. 27: 2. DOI: 10.1016/S0735-1097(96)80200-2  0.314
1995 Zelhof AC, Yao TP, Chen JD, Evans RM, McKeown M. Seven-up inhibits ultraspiracle-based signaling pathways in vitro and in vivo. Molecular and Cellular Biology. 15: 6736-45. PMID 8524239 DOI: 10.1128/MCB.15.12.6736  0.422
1995 Mangelsdorf DJ, Thummel C, Beato M, Herrlich P, Schütz G, Umesono K, Blumberg B, Kastner P, Mark M, Chambon P, Evans RM. The nuclear receptor superfamily: the second decade. Cell. 83: 835-9. PMID 8521507 DOI: 10.1016/0092-8674(95)90199-X  0.514
1995 Kitabayashi I, Chiu R, Umesono K, Evans RM, Gachelin G, Yokoyama K. A novel pathway for retinoic acid-induced differentiation of F9 cells that is distinct from receptor-mediated trans-activation. In Vitro Cellular & Developmental Biology. Animal. 761-8. PMID 7881630 DOI: 10.1007/Bf02631299  0.334
1995 Ogura T, Evans RM. Evidence for two distinct retinoic acid response pathways for HOXB1 gene regulation. Proceedings of the National Academy of Sciences of the United States of America. 92: 392-396. PMID 7831297 DOI: 10.1073/Pnas.92.2.392  0.343
1995 Ogura T, Evans RM. A retinoic acid-triggered cascade of HOXB1 gene activation. Proceedings of the National Academy of Sciences of the United States of America. 92: 387-91. PMID 7831296 DOI: 10.1073/PNAS.92.2.387  0.351
1995 Forman BM, Goode E, Chen J, Oro AE, Bradley DJ, Perlmann T, Noonan DJ, Burka LT, McMorris T, Lamph WW, Evans RM, Weinberger C. Identification of a nuclear receptor that is activated by farnesol metabolites. Cell. 81: 687-93. PMID 7774010 DOI: 10.1016/0092-8674(95)90530-8  0.668
1995 Forman BM, Umesono K, Chen J, Evans RM. Unique response pathways are established by allosteric interactions among nuclear hormone receptors. Cell. 81: 541-50. PMID 7758108 DOI: 10.1016/0092-8674(95)90075-6  0.427
1995 Rastinejad F, Perlmann T, Evans RM, Sigler PB. Structural determinants of nuclear receptor assembly on DNA direct repeats. Nature. 375: 203-11. PMID 7746322 DOI: 10.1038/375203A0  0.367
1995 Willy PJ, Umesono K, Ong ES, Evans RM, Heyman RA, Mangelsdorf DJ. LXR, a nuclear receptor that defines a distinct retinoid response pathway. Genes & Development. 9: 1033-45. PMID 7744246 DOI: 10.1101/GAD.9.9.1033  0.354
1995 Schulman IG, Chakravarti D, Juguilon H, Romo A, Evans RM. Interactions between the retinoid X receptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation Proceedings of the National Academy of Sciences of the United States of America. 92: 8288-8292. PMID 7667283 DOI: 10.1073/Pnas.92.18.8288  0.383
1995 Zhou MD, Sucov HM, Evans RM, Chien KR. Retinoid-dependent pathways suppress myocardial cell hypertrophy Proceedings of the National Academy of Sciences of the United States of America. 92: 7391-7395. PMID 7638203 DOI: 10.1073/Pnas.92.16.7391  0.374
1995 Forman BM, Evans RM. Nuclear hormone receptors activate direct, inverted, and everted repeats. Annals of the New York Academy of Sciences. 761: 29-37. PMID 7625727 DOI: 10.1111/j.1749-6632.1995.tb31366.x  0.417
1995 Stern CD, Yu RT, Kakizuka A, Kintner CR, Mathews LS, Vale WW, Evans RM, Umesono K. Activin and its receptors during gastrulation and the later phases of mesoderm development in the chick embryo. Developmental Biology. 172: 192-205. PMID 7589799 DOI: 10.1006/Dbio.1995.0015  0.379
1995 Sucov HM, Evans RM. Retinoic acid and retinoic acid receptors in development Molecular Neurobiology. 10: 169-184. PMID 7576306 DOI: 10.1007/BF02740674  0.425
1995 Chen JD, Evans RM. A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature. 377: 454-7. PMID 7566127 DOI: 10.1038/377454A0  0.436
1995 Zelhof AC, Yao TP, Evans RM, McKeown M. Identification and characterization of a Drosophila nuclear receptor with the ability to inhibit the ecdysone response. Proceedings of the National Academy of Sciences of the United States of America. 92: 10477-81. PMID 7479823 DOI: 10.1073/pnas.92.23.10477  0.35
1994 Dyck JA, Maul GG, Miller WH, Chen JD, Kakizuka A, Evans RM. A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein Cell. 76: 333-343. PMID 8293467 DOI: 10.1016/0092-8674(94)90340-9  0.38
1994 Yu RT, McKeown M, Evans RM, Umesono K. Relationship between Drosophila gap gene tailless and a vertebrate nuclear receptor Tlx. Nature. 370: 375-9. PMID 8047143 DOI: 10.1038/370375a0  0.397
1994 Kliewer SA, Forman BM, Blumberg B, Ong ES, Borgmeyer U, Mangelsdorf DJ, Umesono K, Evans RM. Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proceedings of the National Academy of Sciences of the United States of America. 91: 7355-9. PMID 8041794 DOI: 10.1073/Pnas.91.15.7355  0.623
1994 Almasan A, Mangelsdorf DJ, Ong ES, Wahl GM, Evans RM. Chromosomal localization of the human retinoid X receptors. Genomics. 20: 397-403. PMID 8034312 DOI: 10.1006/Geno.1994.1193  0.318
1994 Giguère V, Tini M, Flock G, Ong E, Evans RM, Otulakowski G. Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors. Genes & Development. 8: 538-53. PMID 7926749 DOI: 10.1101/Gad.8.5.538  0.302
1994 Lee MS, Sem DS, Kliewer SA, Provencal J, Evans RM, Wright PE. NMR assignments and secondary structure of the retinoid X receptor alpha DNA-binding domain. Evidence for the novel C-terminal helix. European Journal of Biochemistry. 224: 639-50. PMID 7925381 DOI: 10.1111/J.1432-1033.1994.00639.X  0.351
1994 Forman BM, Chen J, Blumberg B, Kliewer SA, Henshaw R, Ong ES, Evans RM. Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors. Molecular Endocrinology. 8: 1253-1261. PMID 7838158 DOI: 10.1210/Mend.8.9.7838158  0.611
1994 Kotomura N, Okada M, Ninomiya Y, Tsukiyama T, Umesono K, Evans RM, Niwa O. Repression of retinoic acid-induced transactivation by embryonal LTR binding protein Journal of Biochemistry. 116: 1309-1316. PMID 7706222 DOI: 10.1093/Oxfordjournals.Jbchem.A124680  0.377
1993 Perlmann T, Rangarajan PN, Umesono K, Evans RM. Determinants for selective RAR and TR recognition of direct repeat HREs. Genes & Development. 7: 1411-22. PMID 8392478 DOI: 10.1101/Gad.7.7B.1411  0.342
1993 Rupprecht R, Arriza JL, Spengler D, Reul JM, Evans RM, Holsboer F, Damm K. Transactivation and synergistic properties of the mineralocorticoid receptor: relationship to the glucocorticoid receptor. Molecular Endocrinology (Baltimore, Md.). 7: 597-603. PMID 8388999 DOI: 10.1210/Mend.7.4.8388999  0.424
1993 Lee MS, Kliewer SA, Provencal J, Wright PE, Evans RM. Structure of the retinoid X receptor alpha DNA binding domain: a helix required for homodimeric DNA binding. Science (New York, N.Y.). 260: 1117-21. PMID 8388124 DOI: 10.1126/Science.8388124  0.314
1993 Yao TP, Forman BM, Jiang Z, Cherbas L, Chen JD, McKeown M, Cherbas P, Evans RM. Functional ecdysone receptor is the product of EcR and Ultraspiracle genes. Nature. 366: 476-9. PMID 8247157 DOI: 10.1038/366476A0  0.429
1993 Damm K, Heyman RA, Umesono K, Evans RM. Functional inhibition of retinoic acid response by dominant negative retinoic acid receptor mutants Proceedings of the National Academy of Sciences of the United States of America. 90: 2989-2993. PMID 8096643 DOI: 10.1073/Pnas.90.7.2989  0.453
1993 Damm K, Evans RM. Identification of a domain required for oncogenic activity and transcriptional suppression by v-erbA and thyroid-hormone receptor α Proceedings of the National Academy of Sciences of the United States of America. 90: 10668-10672. PMID 7902566 DOI: 10.1073/pnas.90.22.10668  0.405
1993 Li E, Sucov HM, Lee KF, Evans RM, Jaenisch R. Normal development and growth of mice carrying a targeted disruption of the α1 retinoic acid receptor gene Proceedings of the National Academy of Sciences of the United States of America. 90: 1590-1594. PMID 7679509 DOI: 10.1073/Pnas.90.4.1590  0.407
1992 Schüle R, Evans RM. Cross-coupling of signal transduction pathways: zinc finger meets leucine zipper. Trends in Genetics : Tig. 7: 377-81. PMID 1668190 DOI: 10.1016/0168-9525(91)90259-S  0.33
1992 Schüle R, Evans RM. Functional antagonism between oncoprotein c-Jun and steroid hormone receptors. Cold Spring Harbor Symposia On Quantitative Biology. 56: 119-27. PMID 1668079 DOI: 10.1101/SQB.1991.056.01.016  0.344
1992 Oro AE, McKeown M, Evans RM. The Drosophila nuclear receptors: new insight into the actions of nuclear receptors in development. Current Opinion in Genetics & Development. 2: 269-74. PMID 1638122 DOI: 10.1016/S0959-437X(05)80284-9  0.65
1992 Cadepond F, Gasc JM, Delahaye F, Jibard N, Schweizer-Groyer G, Segard-Maurel I, Evans R, Baulieu EE. Hormonal regulation of the nuclear localization signals of the human glucocorticosteroid receptor. Experimental Cell Research. 201: 99-108. PMID 1612132 DOI: 10.1016/0014-4827(92)90352-9  0.377
1992 Rangarajan PN, Umesono K, Evans RM. Modulation of glucocorticoid receptor function by protein kinase A. Molecular Endocrinology (Baltimore, Md.). 6: 1451-7. PMID 1435789 DOI: 10.1210/mend.6.9.1435789  0.373
1992 Borrelli E, Sawchenko PE, Evans RM. Pituitary hyperplasia induced by ectopic expression of nerve growth factor. Proceedings of the National Academy of Sciences of the United States of America. 89: 2764-8. PMID 1348359 DOI: 10.1073/Pnas.89.7.2764  0.305
1992 Tsai S, Bartelmez S, Heyman R, Damm K, Evans R, Collins SJ. A mutated retinoic acid receptor-α exhibiting dominant-negative activity alters the lineage development of a multipotent hematopoietic cell line Genes and Development. 6: 2258-2269. PMID 1334022 DOI: 10.1101/Gad.6.12A.2258  0.366
1992 Yao TP, Segraves WA, Oro AE, McKeown M, Evans RM. Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation. Cell. 71: 63-72. PMID 1327536 DOI: 10.1016/0092-8674(92)90266-F  0.661
1992 Kliewer SA, Umesono K, Noonan DJ, Heyman RA, Evans RM. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors Nature. 358: 771-774. PMID 1324435 DOI: 10.1038/358771A0  0.382
1992 Ghazal P, DeMattei C, Giulietti E, Kliewer SA, Umesono K, Evans RM. Retinoic acid receptors initiate induction of the cytomegalovirus enhancer in embryonal cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 7630-4. PMID 1323848 DOI: 10.1073/PNAS.89.16.7630  0.374
1992 Kakizuka A, Sebastian B, Borgmeyer U, Hermans-Borgmeyer I, Bolado J, Hunter T, Hoekstra MF, Evans RM. A mouse cdc25 homolog is differentially and developmentally expressed. Genes & Development. 6: 578-90. PMID 1313771 DOI: 10.1101/Gad.6.4.578  0.321
1992 Blumberg B, Mangelsdorf DJ, Dyck JA, Bittner DA, Evans RM, De Robertis EM. Multiple retinoid-responsive receptors in a single cell: families of retinoid "X" receptors and retinoic acid receptors in the Xenopus egg. Proceedings of the National Academy of Sciences of the United States of America. 89: 2321-5. PMID 1312717 DOI: 10.1073/Pnas.89.6.2321  0.718
1992 Mangelsdorf DJ, Borgmeyer U, Heyman RA, Zhou JY, Ong ES, Oro AE, Kakizuka A, Evans RM. Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes & Development. 6: 329-44. PMID 1312497 DOI: 10.1101/Gad.6.3.329  0.616
1992 Kliewer SA, Umesono K, Heyman RA, Mangelsdorf DJ, Dyck JA, Evans RM. Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America. 89: 1448-1452. PMID 1311101 DOI: 10.1073/Pnas.89.4.1448  0.384
1992 Kliewer SA, Umesono K, Mangelsdorf DJ, Evans RM. Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling. Nature. 355: 446-9. PMID 1310351 DOI: 10.1038/355446A0  0.417
1992 Heyman RA, Mangelsdorf DJ, Dyck JA, Stein RB, Eichele G, Evans RM, Thaller C. 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor. Cell. 68: 397-406. PMID 1310260 DOI: 10.1016/0092-8674(92)90479-V  0.344
1992 Mangelsdorf DJ, Evans RM. 42 Retinoid Receptors as Transcription Factors Cold Spring Harbor Monograph Archive. 1137-1167. DOI: 10.1101/087969425.22B.1137  0.433
1992 Oro AE, McKeown M, Evans RM. The Drosophila nuclear receptors: new insight into the actions of nuclear receptors in development Current Biology. 2: 266. DOI: 10.1016/0960-9822(92)90384-M  0.635
1991 Giguère V, Evans RM. Identification of receptors for retinoids as members of the steroid and thyroid hormone receptor family. Methods in Enzymology. 189: 223-32. PMID 1963457 DOI: 10.1016/0076-6879(90)89293-Q  0.423
1991 Yang N, Schüle R, Mangelsdorf DJ, Evans RM. Characterization of DNA binding and retinoic acid binding properties of retinoic acid receptor. Proceedings of the National Academy of Sciences of the United States of America. 88: 3559-63. PMID 1850832 DOI: 10.1073/PNAS.88.9.3559  0.318
1991 Mangelsdorf DJ, Umesono K, Kliewer SA, Borgmeyer U, Ong ES, Evans RM. A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR. Cell. 66: 555-61. PMID 1651173 DOI: 10.1016/0092-8674(81)90018-0  0.42
1991 Schüle R, Rangarajan P, Yang N, Kliewer S, Ransone LJ, Bolado J, Verma IM, Evans RM. Retinoic acid is a negative regulator of AP-1-responsive genes. Proceedings of the National Academy of Sciences of the United States of America. 88: 6092-6. PMID 1648728 DOI: 10.1073/Pnas.88.14.6092  0.377
1991 Umesono K, Murakami KK, Thompson CC, Evans RM. Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors. Cell. 65: 1255-66. PMID 1648450 DOI: 10.1016/0092-8674(91)90020-Y  0.509
1990 Ishikawa T, Umesono K, Mangelsdorf DJ, Aburatani H, Stanger BZ, Shibasaki Y, Imawari M, Evans RM, Takaku F. A functional retinoic acid receptor encoded by the gene on human chromosome 12 Molecular Endocrinology. 4: 837-844. PMID 2172793 DOI: 10.1210/Mend-4-6-837  0.349
1990 Oro AE, McKeown M, Evans RM. Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor. Nature. 347: 298-301. PMID 2169594 DOI: 10.1038/347298A0  0.652
1990 Schüle R, Rangarajan P, Kliewer S, Ransone LJ, Bolado J, Yang N, Verma IM, Evans RM. Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor. Cell. 62: 1217-26. PMID 2169353 DOI: 10.1016/0092-8674(90)90397-W  0.384
1990 Sucov HM, Murakami KK, Evans RM. Characterization of an autoregulated response element in the mouse retinoic acid receptor type β gene Proceedings of the National Academy of Sciences of the United States of America. 87: 5392-5396. PMID 2164682 DOI: 10.1073/Pnas.87.14.5392  0.406
1990 Schüle R, Umesono K, Mangelsdorf DJ, Bolado J, Pike JW, Evans RM. Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene. Cell. 61: 497-504. PMID 2159384 DOI: 10.1016/0092-8674(90)90531-I  0.357
1990 Mangelsdorf DJ, Ong ES, Dyck JA, Evans RM. Nuclear receptor that identifies a novel retinoic acid response pathway. Nature. 345: 224-9. PMID 2159111 DOI: 10.1038/345224A0  0.419
1989 Evans RM, Hollenberg SM. Cooperative and positional independent trans-activation domains of the human glucocorticoid receptor. Cold Spring Harbor Symposia On Quantitative Biology. 813-8. PMID 3254785 DOI: 10.1101/SQB.1988.053.01.092  0.335
1989 Hollenberg SM, Evans RM. Multiple and cooperative trans-activation domains of the human glucocorticoid receptor. Cell. 55: 899-906. PMID 3191531 DOI: 10.1016/0092-8674(88)90145-6  0.357
1989 Damm K, Thompson CC, Evans RM. Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist. Nature. 339: 593-7. PMID 2733791 DOI: 10.1038/339593a0  0.544
1989 Borrelli E, Heyman RA, Arias C, Sawchenko PE, Evans RM. Transgenic mice with inducible dwarfism. Nature. 339: 538-41. PMID 2733785 DOI: 10.1038/339538A0  0.324
1989 Thompson CC, Evans RM. Trans-activation by thyroid hormone receptors: functional parallels with steroid hormone receptors. Proceedings of the National Academy of Sciences of the United States of America. 86: 3494-8. PMID 2726731 DOI: 10.1073/Pnas.86.10.3494  0.565
1989 Evans RM, Arriza JL. A molecular framework for the actions of glucocorticoid hormones in the nervous system. Neuron. 2: 1105-1112. PMID 2696502 DOI: 10.1016/0896-6273(89)90177-3  0.426
1989 Evans RM. Molecular characterization of the glucocorticoid receptor. Recent Progress in Hormone Research. 45: 1-27. PMID 2682841 DOI: 10.1016/B978-0-12-571145-6.50005-4  0.455
1989 Evans RM. The v-erbA oncogene is a thyroid hormone receptor antagonist. International Journal of Cancer. Supplement = Journal International Du Cancer. Supplement. 4: 26-8. PMID 2572567 DOI: 10.1002/IJC.2910440707  0.372
1989 Heyman RA, Borrelli E, Lesley J, Anderson D, Richman DD, Baird SM, Hyman R, Evans RM. Thymidine kinase obliteration: Creation of transgenic mice with controlled immune deficiency Proceedings of the National Academy of Sciences of the United States of America. 86: 2698-2702. PMID 2539597 DOI: 10.1073/pnas.86.8.2698  0.307
1989 Giguere V, Ong ES, Evans RM, Tabin CJ. Spatial and temporal expression of the retinoic acid receptor in the regenerating amphibian limb Nature. 337: 566-569. PMID 2536901 DOI: 10.1038/337566A0  0.384
1989 Umesono K, Evans RM. Determinants of target gene specificity for steroid/thyroid hormone receptors. Cell. 57: 1139-46. PMID 2500251 DOI: 10.1016/0092-8674(89)90051-2  0.401
1988 Waterman ML, Adler S, Nelson C, Greene GL, Evans RM, Rosenfeld MG. A single domain of the estrogen receptor confers deoxyribonucleic acid binding and transcriptional activation of the rat prolactin gene. Molecular Endocrinology (Baltimore, Md.). 2: 14-21. PMID 3398840 DOI: 10.1210/Mend-2-1-14  0.415
1988 Evans RM. The steroid and thyroid hormone receptor superfamily. Science (New York, N.Y.). 240: 889-95. PMID 3283939 DOI: 10.1126/SCIENCE.3283939  0.413
1988 Giguère V, Yang N, Segui P, Evans RM. Identification of a new class of steroid hormone receptors. Nature. 331: 91-4. PMID 3267207 DOI: 10.1038/331091A0  0.408
1988 Oro AE, Hollenberg SM, Evans RM. Transcriptional inhibition by a glucocorticoid receptor-β-galactosidase fusion protein Cell. 55: 1109-1114. PMID 3144438 DOI: 10.1016/0092-8674(88)90255-3  0.655
1988 Mayo KE, Hammer RE, Swanson LW, Brinster RL, Rosenfeld MG, Evans RM. Dramatic pituitary hyperplasia in transgenic mice expressing a human growth hormone-releasing factor gene. Molecular Endocrinology (Baltimore, Md.). 2: 606-12. PMID 3137455 DOI: 10.1210/Mend-2-7-606  0.342
1988 Evans RM, Hollenbergt SM. Zinc fingers: gilt by association. Cell. 52: 1-3. PMID 3125980 DOI: 10.1016/0092-8674(88)90522-3  0.319
1988 Arriza JL, Simerly RB, Swanson LW, Evans RM. The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response. Neuron. 1: 887-900. PMID 2856104 DOI: 10.1016/0896-6273(88)90136-5  0.376
1988 Oro AE, Ong ES, Margolis JS, Posakony JW, McKeown M, Evans RM. The Drosophila gene knirps-related is a member of the steroid-receptor gene superfamily. Nature. 336: 493-6. PMID 2848202 DOI: 10.1038/336493a0  0.623
1988 Umesono K, Giguere V, Glass CK, Rosenfeld MG, Evans RM. Retinoic acid and thyroid hormone induce gene expression through a common responsive element Nature. 336: 262-265. PMID 2848197 DOI: 10.1038/336262A0  0.426
1987 Hollenberg SM, Giguere V, Segui P, Evans RM. Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor. Cell. 49: 39-46. PMID 3829127 DOI: 10.1016/0092-8674(87)90753-7  0.387
1987 Thompson CC, Weinberger C, Lebo R, Evans RM. Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system. Science (New York, N.Y.). 237: 1610-4. PMID 3629259 DOI: 10.1126/Science.3629259  0.55
1987 Glass CK, Franco R, Weinberger C, Albert VR, Evans RM, Rosenfeld MG. A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone. Nature. 329: 738-41. PMID 3313046 DOI: 10.1038/329738a0  0.379
1987 Botteri FM, van der Putten H, Wong DF, Sauvage CA, Evans RM. Unexpected thymic hyperplasia in transgenic mice harboring a neuronal promoter fused with simian virus 40 large T antigen. Molecular and Cellular Biology. 7: 3178-84. PMID 3118193 DOI: 10.1128/MCB.7.9.3178  0.321
1987 Arriza JL, Weinberger C, Cerelli G, Glaser TM, Handelin BL, Housman DE, Evans RM. Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. Science (New York, N.Y.). 237: 268-75. PMID 3037703 DOI: 10.1126/Science.3037703  0.417
1987 Weinberger C, Giguere V, Hollenberg S, Rosenfeld MG, Evans RM. Human steroid receptors and erbA proto-oncogene products: members of a new superfamily of enhancer binding proteins. Cold Spring Harbor Symposia On Quantitative Biology. 759-72. PMID 3034496 DOI: 10.1101/Sqb.1986.051.01.089  0.338
1987 Leff SE, Evans RM, Rosenfeld MG. Splice commitment dictates neuron-specific alternative RNA processing in calcitonin/CGRP gene expression. Cell. 48: 517-24. PMID 2879637 DOI: 10.1016/0092-8674(87)90202-9  0.309
1987 Giguere V, Ong ES, Segui P, Evans RM. Identification of a receptor for the morphogen retinoic acid. Nature. 330: 624-629. PMID 2825036 DOI: 10.1038/330624A0  0.421
1986 Weinberger C, Hollenberg SM, Rosenfeld MG, Evans RM. Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product. Nature. 318: 670-2. PMID 3841189 DOI: 10.1038/318670A0  0.447
1986 Giguère V, Hollenberg SM, Rosenfeld MG, Evans RM. Functional domains of the human glucocorticoid receptor. Cell. 46: 645-52. PMID 3742595 DOI: 10.1016/0092-8674(86)90339-9  0.401
1986 Nelson C, Crenshaw EB, Franco R, Lira SA, Albert VR, Evans RM, Rosenfeld MG. Discrete cis-active genomic sequences dictate the pituitary cell type-specific expression of rat prolactin and growth hormone genes Nature. 322: 557-562. PMID 3736673 DOI: 10.1038/322557a0  0.315
1986 Elsholtz HP, Mangalam HJ, Potter E, Albert VR, Supowit S, Evans RM, Rosenfeld MG. Two different cis-active elements transfer the transcriptional effects of both EGF and phorbol esters. Science (New York, N.Y.). 234: 1552-7. PMID 3491428 DOI: 10.1126/science.3491428  0.337
1986 Leff SE, Rosenfeld MG, Evans RM. Complex transcriptional units: diversity in gene expression by alternative RNA processing. Annual Review of Biochemistry. 55: 1091-117. PMID 3017190 DOI: 10.1146/ANNUREV.BI.55.070186.005303  0.335
1986 Lin CR, Chen WS, Lazar CS, Carpenter CD, Gill GN, Evans RM, Rosenfeld MG. Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms. Cell. 44: 839-48. PMID 3006920 DOI: 10.1016/0092-8674(86)90006-1  0.379
1986 Weinberger C, Thompson CC, Ong ES, Lebo R, Gruol DJ, Evans RM. The c-erb-A gene encodes a thyroid hormone receptor. Nature. 324: 641-6. PMID 2879243 DOI: 10.1038/324641a0  0.555
1986 Hollenberg SM, Weinberger C, Ong ES, Cerelli G, Oro A, Lebo R, Thompson EB, Rosenfeld MG, Evans RM. Primary structure and expression of a functional human glucocorticoid receptor cDNA. Nature. 318: 635-41. PMID 2867473 DOI: 10.1038/318635A0  0.636
1985 Evans RM, Swanson L, Rosenfeld MG. Creation of transgenic animals to study development and as models for human disease. Recent Progress in Hormone Research. 41: 317-37. PMID 4048636 DOI: 10.1016/B978-0-12-571141-8.50011-1  0.347
1985 Swanson LW, Simmons DM, Arriza J, Hammer R, Brinster R, Rosenfeld MG, Evans RM. Novel developmental specificity in the nervous system of transgenic animals expressing growth hormone fusion genes. Nature. 317: 363-6. PMID 4047165 DOI: 10.1038/317363A0  0.346
1985 Hammer RE, Brinster RL, Rosenfeld MG, Evans RM, Mayo KE. Expression of human growth hormone-releasing factor in transgenic mice results in increased somatic growth Nature. 315: 413-416. PMID 3923368 DOI: 10.1038/315413a0  0.316
1985 Waterman M, Murdoch GH, Evans RM, Rosenfeld MG. Cyclic AMP regulation of eukaryotic gene transcription by two discrete molecular mechanisms. Science (New York, N.Y.). 229: 267-9. PMID 2990047 DOI: 10.1126/Science.2990047  0.346
1985 Weinberger C, Hollenberg SM, Ong ES, Harmon JM, Brower ST, Cidlowski J, Thompson EB, Rosenfeld MG, Evans RM. Identification of human glucocorticoid receptor complementary DNA clones by epitope selection Science. 228: 740-742. PMID 2581314 DOI: 10.1126/Science.2581314  0.411
1985 Gill GN, Weber W, Thompson DM, Lin C, Evans RM, Rosenfeld MG, Gamou S, Shimizu N. Relationship between production of epidermal growth factor receptors, gene amplification, and chromosome 7 translocation in variant A431 cells. Somatic Cell and Molecular Genetics. 11: 309-18. PMID 2410984 DOI: 10.1007/BF01534689  0.384
1984 Supowit SC, Potter E, Evans RM, Rosenfeld MG. Polypeptide hormone regulation of gene transcription: specific 5' genomic sequences are required for epidermal growth factor and phorbol ester regulation of prolactin gene expression. Proceedings of the National Academy of Sciences of the United States of America. 81: 2975-9. PMID 6328483 DOI: 10.1073/pnas.81.10.2975  0.335
1984 Lin CR, Chen WS, Kruiger W, Stolarsky LS, Weber W, Evans RM, Verma IM, Gill GN, Rosenfeld MG. Expression cloning of human EGF receptor complementary DNA: gene amplification and three related messenger RNA products in A431 cells. Science (New York, N.Y.). 224: 843-8. PMID 6326261 DOI: 10.1126/Science.6326261  0.391
1984 Rosenfeld MG, Amara SG, Evans RM. Alternative RNA processing: determining neuronal phenotype. Science (New York, N.Y.). 225: 1315-20. PMID 6089345 DOI: 10.1126/SCIENCE.6089345  0.304
1983 Palmiter RD, Brinster RL, Hammer RE, Trumbauer ME, Rosenfeld MG, Birnberg NC, Evans RM. Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes. Nature. 300: 611-5. PMID 6958982 DOI: 10.1038/300611a0  0.302
1983 Rosenfeld MG, Amara SG, Birnberg NC, Mermod JJ, Murdoch GH, Evans RM. Calcitonin, prolactin, and growth hormone gene expression as model systems for the characterization of neuroendocrine regulation. Recent Progress in Hormone Research. 39: 305-51. PMID 6415768 DOI: 10.1016/B978-0-12-571139-5.50012-4  0.351
1983 Evans RM, Birnberg NC, Rosenfeld MG. Glucocorticoid and thyroid hormones transcriptionally regulate growth hormone gene expression. Proceedings of the National Academy of Sciences of the United States of America. 79: 7659-63. PMID 6296844 DOI: 10.1073/PNAS.79.24.7659  0.322
1982 Murdoch GH, Potter E, Nicolaisen AK, Evans RM, Rosenfeld MG. Epidermal growth factor rapidly stimulates prolactin gene transcription. Nature. 300: 192-4. PMID 6982423 DOI: 10.1038/300192A0  0.334
1982 Potter E, Nicolaisen AK, Ong ES, Evans RM, Rosenfeld MG. Thyrotropin-releasing hormone exerts rapid nuclear effects to increase production of the primary prolactin mRNA transcript. Proceedings of the National Academy of Sciences of the United States of America. 78: 6662-6. PMID 6796963 DOI: 10.1073/PNAS.78.11.6662  0.339
1982 Doehmer J, Barinaga M, Vale W, Rosenfeld MG, Verma IM, Evans RM. Introduction of rat growth hormone gene into mouse fibroblasts via a retroviral DNA vector: expression and regulation. Proceedings of the National Academy of Sciences of the United States of America. 79: 2268-72. PMID 6285377 DOI: 10.1073/Pnas.79.7.2268  0.309
1981 Rosenfeld MG, Amara SG, Roos BA, Ong ES, Evans RM. Altered expression of the calcitonin gene associated with RNA polymorphism. Nature. 290: 63-5. PMID 7207587 DOI: 10.1038/290063a0  0.341
1979 Harpold MM, Dobner PR, Evans R, Bancroft FC, Darnell JE. The synthesis and processing of a nuclear RNA precursor to rat pregrowth hormone messenger RNA. Nucleic Acids Research. 6: 3133-44. PMID 493135 DOI: 10.1093/NAR/6.9.3133  0.473
1979 Harpold MM, Evans RM, Salditt-Georgieff M, Darnell JE. Production of mRNA in Chinese hamster cells: relationship of the rate of synthesis to the cytoplasmic concentration of nine specific mRNA sequences. Cell. 17: 1025-35. PMID 487428 DOI: 10.1016/0092-8674(79)90341-6  0.475
1979 Soreq H, Harpold M, Evans R, Darnell JE, Bancroft FC. Rat growth hormone gene: intervening sequences separate the mRNA regions. Nucleic Acids Research. 6: 2471-82. PMID 461195 DOI: 10.1093/Nar/6.7.2471  0.587
1979 Evans R, Weber J, Ziff E, Darnell JE. Premature termination during adenovirus transcription. Nature. 278: 367-70. PMID 423992 DOI: 10.1038/278367A0  0.526
1978 Darnell JE, Evans R, Fraser N, Goldberg S, Nevins J, Salditt-Georgieff M, Schwartz H, Weber J, Ziff E. The definition of transcription units for mRNA. Cold Spring Harbor Symposia On Quantitative Biology. 42: 515-22. PMID 277360 DOI: 10.1101/Sqb.1978.042.01.054  0.494
1978 Jelinek W, Evans R, Wilson M, Salditt-Georgieff M, Darnell JE. Oligonucleotides in heterogeneous nuclear RNA: similarity of inverted repeats and RNA from repetitious DNA sites. Biochemistry. 17: 2776-83. PMID 99161 DOI: 10.1021/Bi00607A012  0.467
1977 Evans RM, Fraser N, Ziff E, Weber J, Wilson M, Darnell JE. The initiation sites for RNA transcription in Ad2 DNA. Cell. 12: 733-9. PMID 922890 DOI: 10.1016/0092-8674(77)90273-2  0.476
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