David D. Ginty - Publications

Johns Hopkins University School of Medicine, Baltimore, MD, United States 
 Harvard Medical School, Boston, MA, United States 
signaling, neurotrophins, development, trophic factors

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Santiago C, Sharma N, Africawala N, Siegrist J, Handler A, Tasnim A, Anjum R, Turecek J, Lehnert BP, Renauld S, Nolan-Tamariz M, Iskols M, Magee AR, Paradis S, Ginty DD. Activity-dependent development of the body's touch receptors. Biorxiv : the Preprint Server For Biology. PMID 37790437 DOI: 10.1101/2023.09.23.559109  0.826
2023 Handler A, Zhang Q, Pang S, Nguyen TM, Iskols M, Nolan-Tamariz M, Cattel S, Plumb R, Sanchez B, Ashjian K, Shotland A, Brown B, Kabeer M, Turecek J, DeLisle MM, ... ... Ginty DD, et al. Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch. Neuron. PMID 37725982 DOI: 10.1016/j.neuron.2023.08.023  0.817
2023 Koutsioumpa C, Santiago C, Jacobs K, Lehnert BP, Barrera V, Hutchinson JN, Schmelyun D, Lehoczky JA, Paul DL, Ginty DD. Skin-type-dependent development of murine mechanosensory neurons. Developmental Cell. PMID 37607547 DOI: 10.1016/j.devcel.2023.07.020  0.818
2023 Wolfson RL, Abdelaziz A, Rankin G, Kushner S, Qi L, Mazor O, Choi S, Sharma N, Ginty DD. DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon. Cell. 186: 3368-3385.e18. PMID 37541195 DOI: 10.1016/j.cell.2023.07.007  0.805
2023 Qi L, Iskols M, Handler A, Ginty DD. Krause corpuscles of the genitalia are vibrotactile sensors required for normal sexual behavior. Biorxiv : the Preprint Server For Biology. PMID 37398085 DOI: 10.1101/2023.06.14.545006  0.789
2023 Liu D, Rahman M, Johnson A, Tsutsui-Kimura I, Pena N, Talay M, Logeman BL, Finkbeiner S, Choi S, Capo-Battaglia A, Abdus-Saboor I, Ginty DD, Uchida N, Watabe-Uchida M, Dulac C. A Hypothalamic Circuit Underlying the Dynamic Control of Social Homeostasis. Biorxiv : the Preprint Server For Biology. PMID 37293031 DOI: 10.1101/2023.05.19.540391  0.755
2023 Tasnim A, Alkislar I, Hakim R, Turecek J, Abdelaziz A, Orefice LL, Ginty DD. The developmental timing of spinal touch processing alterations and its relation to ASD-associated behaviors in mouse models. Biorxiv : the Preprint Server For Biology. PMID 37214862 DOI: 10.1101/2023.05.09.539589  0.778
2023 Qi L, Iskols M, Shi D, Reddy P, Walker C, Lezgiyeva K, Voisin T, Pawlak M, Kuchroo VK, Chiu I, Ginty DD, Sharma N. A DRG genetic toolkit reveals molecular, morphological, and functional diversity of somatosensory neuron subtypes. Biorxiv : the Preprint Server For Biology. PMID 37131664 DOI: 10.1101/2023.04.22.537932  0.792
2023 Meltzer S, Boulanger KC, Chirila AM, Osei-Asante E, DeLisle M, Zhang Q, Kalish BT, Tasnim A, Huey EL, Fuller LC, Flaherty EK, Maniatis T, Garrett AM, Weiner JA, Ginty DD. γ-Protocadherins control synapse formation and peripheral branching of touch sensory neurons. Neuron. PMID 37028432 DOI: 10.1016/j.neuron.2023.03.012  0.601
2023 Koropouli E, Wang Q, Mejías R, Hand R, Wang T, Ginty DD, Kolodkin AL. Palmitoylation regulates neuropilin-2 localization and function in cortical neurons and conveys specificity to semaphorin signaling via palmitoyl acyltransferases. Elife. 12. PMID 37010951 DOI: 10.7554/eLife.83217  0.624
2023 Handler A, Zhang Q, Pang S, Nguyen TM, Iskols M, Nolan-Tamariz M, Cattel S, Plumb R, Sanchez B, Ashjian K, Shotland A, Brown B, Kabeer M, Turecek J, Rankin G, ... ... Ginty DD, et al. Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch. Biorxiv : the Preprint Server For Biology. PMID 36993253 DOI: 10.1101/2023.03.17.533188  0.804
2023 Rankin G, Chirila AM, Emanuel AJ, Zhang Z, Woolf CJ, Drugowitsch J, Ginty DD. Nerve injury disrupts temporal processing in the spinal cord dorsal horn through alterations in PV interneurons. Biorxiv : the Preprint Server For Biology. PMID 36993199 DOI: 10.1101/2023.03.20.533541  0.789
2022 Turecek J, Lehnert BP, Ginty DD. The encoding of touch by somatotopically aligned dorsal column subdivisions. Nature. PMID 36418401 DOI: 10.1038/s41586-022-05470-x  0.823
2022 Chirila AM, Rankin G, Tseng SY, Emanuel AJ, Chavez-Martinez CL, Zhang D, Harvey CD, Ginty DD. Mechanoreceptor signal convergence and transformation in the dorsal horn flexibly shape a diversity of outputs to the brain. Cell. PMID 36334588 DOI: 10.1016/j.cell.2022.10.012  0.823
2022 Meltzer S, Boulanger KC, Osei-Asante E, Handler A, Zhang Q, Sano C, Itohara S, Ginty DD. A role for axon-glial interactions and Netrin-G1 signaling in the formation of low-threshold mechanoreceptor end organs. Proceedings of the National Academy of Sciences of the United States of America. 119: e2210421119. PMID 36252008 DOI: 10.1073/pnas.2210421119  0.813
2021 Emanuel AJ, Lehnert BP, Panzeri S, Harvey CD, Ginty DD. Cortical responses to touch reflect subcortical integration of LTMR signals. Nature. 600: 680-685. PMID 34789880 DOI: 10.1038/s41586-021-04094-x  0.797
2021 Lehnert BP, Santiago C, Huey EL, Emanuel AJ, Renauld S, Africawala N, Alkislar I, Zheng Y, Bai L, Koutsioumpa C, Hong JT, Magee AR, Harvey CD, Ginty DD. Mechanoreceptor synapses in the brainstem shape the central representation of touch. Cell. PMID 34637701 DOI: 10.1016/j.cell.2021.09.023  0.774
2021 Meltzer S, Santiago C, Sharma N, Ginty DD. The cellular and molecular basis of somatosensory neuron development. Neuron. PMID 34592169 DOI: 10.1016/j.neuron.2021.09.004  0.603
2021 Handler A, Ginty DD. The mechanosensory neurons of touch and their mechanisms of activation. Nature Reviews. Neuroscience. PMID 34312536 DOI: 10.1038/s41583-021-00489-x  0.82
2020 Choi S, Hachisuka J, Brett MA, Magee AR, Omori Y, Iqbal NU, Zhang D, DeLisle MM, Wolfson RL, Bai L, Santiago C, Gong S, Goulding M, Heintz N, Koerber HR, ... ... Ginty DD, et al. Parallel ascending spinal pathways for affective touch and pain. Nature. PMID 33116307 DOI: 10.1038/s41586-020-2860-1  0.828
2020 Neubarth NL, Emanuel AJ, Liu Y, Springel MW, Handler A, Zhang Q, Lehnert BP, Guo C, Orefice LL, Abdelaziz A, DeLisle MM, Iskols M, Rhyins J, Kim SJ, Cattel SJ, ... ... Ginty DD, et al. Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception. Science (New York, N.Y.). 368. PMID 32554568 DOI: 10.1126/Science.Abb2751  0.757
2020 Sharma N, Flaherty K, Lezgiyeva K, Wagner DE, Klein AM, Ginty DD. The emergence of transcriptional identity in somatosensory neurons. Nature. PMID 31915380 DOI: 10.1038/S41586-019-1900-1  0.428
2019 Orefice LL, Mosko JR, Morency DT, Wells MF, Tasnim A, Mozeika SM, Ye M, Chirila AM, Emanuel AJ, Rankin G, Fame RM, Lehtinen MK, Feng G, Ginty DD. Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models. Cell. 178: 867-886.e24. PMID 31398341 DOI: 10.1016/J.Cell.2019.07.024  0.777
2019 Boyle KA, Gradwell MA, Yasaka T, Dickie AC, Polgár E, Ganley RP, Orr DPH, Watanabe M, Abraira VE, Kuehn ED, Zimmerman AL, Ginty DD, Callister RJ, Graham BA, Hughes DI. Defining a Spinal Microcircuit that Gates Myelinated Afferent Input: Implications for Tactile Allodynia. Cell Reports. 28: 526-540.e6. PMID 31291586 DOI: 10.1016/J.Celrep.2019.06.040  0.801
2019 Zheng Y, Liu P, Bai L, Trimmer JS, Bean BP, Ginty DD. Deep Sequencing of Somatosensory Neurons Reveals Molecular Determinants of Intrinsic Physiological Properties. Neuron. PMID 31248728 DOI: 10.1016/J.Neuron.2019.05.039  0.651
2019 Zeng X, Ye M, Resch JM, Jedrychowski MP, Hu B, Lowell BB, Ginty DD, Spiegelman BM. Innervation of thermogenic adipose tissue via a calsyntenin 3β-S100b axis. Nature. PMID 31043739 DOI: 10.1038/S41586-019-1156-9  0.313
2019 Kuehn ED, Meltzer S, Abraira VE, Ho CY, Ginty DD. Tiling and somatotopic alignment of mammalian low-threshold mechanoreceptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 30996124 DOI: 10.1073/Pnas.1901378116  0.812
2019 Zhang Q, Lee WA, Paul DL, Ginty DD. Multiplexed peroxidase-based electron microscopy labeling enables simultaneous visualization of multiple cell types. Nature Neuroscience. PMID 30886406 DOI: 10.1038/S41593-019-0358-7  0.355
2019 Zimmerman AL, Kovatsis EM, Poszgai RY, Tasnim A, Zhang Q, Ginty DD. Distinct Modes of Presynaptic Inhibition of Cutaneous Afferents and Their Functions in Behavior. Neuron. PMID 30826183 DOI: 10.1016/J.Neuron.2019.02.002  0.699
2018 Ye M, Lehigh KM, Ginty DD. Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling. Elife. 7. PMID 29381137 DOI: 10.7554/eLife.33012  0.393
2017 Wang Q, Chiu SL, Koropouli E, Hong I, Mitchell S, Easwaran TP, Hamilton NR, Gustina AS, Zhu Q, Ginty DD, Huganir RL, Kolodkin AL. Neuropilin-2/PlexinA3 Receptors Associate with GluA1 and Mediate Sema3F-Dependent Homeostatic Scaling in Cortical Neurons. Neuron. PMID 29154130 DOI: 10.1016/J.Neuron.2017.10.029  0.641
2017 Browne LE, Latremoliere A, Lehnert BP, Grantham A, Ward C, Alexandre C, Costigan M, Michoud F, Roberson DP, Ginty DD, Woolf CJ. Time-Resolved Fast Mammalian Behavior Reveals the Complexity of Protective Pain Responses. Cell Reports. 20: 89-98. PMID 28683326 DOI: 10.1016/J.Celrep.2017.06.024  0.806
2017 Severson KS, Xu D, Van de Loo M, Bai L, Ginty DD, O'Connor DH. Active Touch and Self-Motion Encoding by Merkel Cell-Associated Afferents. Neuron. PMID 28434802 DOI: 10.1016/J.Neuron.2017.03.045  0.53
2017 Andreone BJ, Chow BW, Tata A, Lacoste B, Ben-Zvi A, Bullock K, Deik AA, Ginty DD, Clish CB, Gu C. Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis. Neuron. PMID 28416077 DOI: 10.1016/J.Neuron.2017.03.043  0.766
2017 Lehigh KM, West KM, Ginty DD. Retrogradely Transported TrkA Endosomes Signal Locally within Dendrites to Maintain Sympathetic Neuron Synapses. Cell Reports. 19: 86-100. PMID 28380365 DOI: 10.1016/j.celrep.2017.03.028  0.445
2016 Abraira VE, Kuehn ED, Chirila AM, Springel MW, Toliver AA, Zimmerman AL, Orefice LL, Boyle KA, Bai L, Song BJ, Bashista KA, O'Neill TG, Zhuo J, Tsan C, Hoynoski J, ... ... Ginty DD, et al. The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn. Cell. PMID 28041852 DOI: 10.1016/J.Cell.2016.12.010  0.799
2016 Orefice LL, Zimmerman AL, Chirila AM, Sleboda SJ, Head JP, Ginty DD. Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral Deficits in Mouse Models of ASDs. Cell. PMID 27293187 DOI: 10.1016/j.cell.2016.05.033  0.8
2015 Rutlin M, Ho CY, Abraira VE, Cassidy C, Bai L, Woodbury CJ, Ginty DD. The Cellular and Molecular Basis of Direction Selectivity of Aδ-LTMRs. Cell. 160: 1027. PMID 29698636 DOI: 10.1016/J.Cell.2015.02.013  0.756
2015 Bai L, Lehnert BP, Liu J, Neubarth NL, Dickendesher TL, Nwe PH, Cassidy C, Woodbury CJ, Ginty DD. Genetic Identification of an Expansive Mechanoreceptor Sensitive to Skin Stroking. Cell. 163: 1783-95. PMID 26687362 DOI: 10.1016/J.Cell.2015.11.060  0.776
2015 Wright KM, Lyon K, Ginty D. Dystroglycan is a critical regulator of forebrain connectivity. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 47: 117. PMID 26531637 DOI: 10.1016/j.ijdevneu.2015.04.315  0.77
2015 Huang S, O'Donovan KJ, Turner EE, Zhong J, Ginty DD. Extrinsic and intrinsic signals converge on the Runx1/CBFβ transcription factor for nonpeptidergic nociceptor maturation. Elife. 4. PMID 26418744 DOI: 10.7554/Elife.10874  0.4
2014 Rutlin M, Ho CY, Abraira VE, Cassidy C, Bai L, Woodbury CJ, Ginty DD. The cellular and molecular basis of direction selectivity of Aδ-LTMRs. Cell. 159: 1640-51. PMID 25525881 DOI: 10.1016/J.Cell.2014.11.038  0.801
2014 Zimmerman A, Bai L, Ginty DD. The gentle touch receptors of mammalian skin. Science (New York, N.Y.). 346: 950-4. PMID 25414303 DOI: 10.1126/Science.1254229  0.761
2014 Mandai K, Reimert DV, Ginty DD. Linx mediates interaxonal interactions and formation of the internal capsule. Neuron. 83: 93-103. PMID 24930700 DOI: 10.1016/j.neuron.2014.05.020  0.326
2014 Li L, Ginty DD. The structure and organization of lanceolate mechanosensory complexes at mouse hair follicles. Elife. 3: e01901. PMID 24569481 DOI: 10.7554/Elife.01901  0.457
2014 Li L, Ginty DD. Author response: The structure and organization of lanceolate mechanosensory complexes at mouse hair follicles Elife. DOI: 10.7554/Elife.01901.019  0.466
2014 de Anda FC, Rosario AL, Durak O, Tran T, Gräff J, Meletis K, Rei D, Soda T, Madabhushi R, Ginty DD, Kolodkin AL, Tsai L. Erratum: Corrigendum: Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex Nature Neuroscience. 17: 1840-1840. DOI: 10.1038/Nn1214-1840A  0.54
2013 Engelhard C, Sarsfield S, Merte J, Wang Q, Li P, Beppu H, Kolodkin AL, Sucov HM, Ginty DD. MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons. Elife. 2: e01160. PMID 24052814 DOI: 10.7554/Elife.01160  0.816
2013 Abraira VE, Ginty DD. The sensory neurons of touch. Neuron. 79: 618-39. PMID 23972592 DOI: 10.1016/j.neuron.2013.07.051  0.767
2013 Harrington AW, Ginty DD. Long-distance retrograde neurotrophic factor signalling in neurons. Nature Reviews. Neuroscience. 14: 177-87. PMID 23422909 DOI: 10.1038/nrn3253  0.458
2013 Engelhard C, Sarsfield S, Merte J, Wang Q, Li P, Beppu H, Kolodkin AL, Sucov HM, Ginty DD. Author response: MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons Elife. DOI: 10.7554/Elife.01160.019  0.816
2012 Liu Y, Rutlin M, Huang S, Barrick CA, Wang F, Jones KR, Tessarollo L, Ginty DD. Sexually dimorphic BDNF signaling directs sensory innervation of the mammary gland. Science (New York, N.Y.). 338: 1357-60. PMID 23224557 DOI: 10.1126/Science.1228258  0.786
2012 Wright KM, Lyon KA, Leung H, Leahy DJ, Ma L, Ginty DD. Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Neuron. 76: 931-44. PMID 23217742 DOI: 10.1016/J.Neuron.2012.10.009  0.787
2012 de Anda FC, Rosario AL, Durak O, Tran T, Gräff J, Meletis K, Rei D, Soda T, Madabhushi R, Ginty DD, Kolodkin AL, Tsai LH. Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex. Nature Neuroscience. 15: 1022-31. PMID 22683681 DOI: 10.1038/Nn.3141  0.669
2011 Li L, Rutlin M, Abraira VE, Cassidy C, Kus L, Gong S, Jankowski MP, Luo W, Heintz N, Koerber HR, Woodbury CJ, Ginty DD. The functional organization of cutaneous low-threshold mechanosensory neurons. Cell. 147: 1615-27. PMID 22196735 DOI: 10.1016/J.Cell.2011.11.027  0.815
2011 Harrington AW, St Hillaire C, Zweifel LS, Glebova NO, Philippidou P, Halegoua S, Ginty DD. Recruitment of actin modifiers to TrkA endosomes governs retrograde NGF signaling and survival. Cell. 146: 421-34. PMID 21816277 DOI: 10.1016/J.Cell.2011.07.008  0.782
2011 Guo T, Mandai K, Condie BG, Wickramasinghe SR, Capecchi MR, Ginty DD. An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates. Nature Neuroscience. 14: 31-6. PMID 21151121 DOI: 10.1038/Nn.2710  0.693
2010 Sharma N, Deppmann CD, Harrington AW, St Hillaire C, Chen ZY, Lee FS, Ginty DD. Long-distance control of synapse assembly by target-derived NGF. Neuron. 67: 422-34. PMID 20696380 DOI: 10.1016/J.Neuron.2010.07.018  0.717
2010 Merte J, Wang Q, Vander Kooi CW, Sarsfield S, Leahy DJ, Kolodkin AL, Ginty DD. A forward genetic screen in mice identifies Sema3A(K108N), which binds to neuropilin-1 but cannot signal. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5767-75. PMID 20410128 DOI: 10.1523/Jneurosci.5061-09.2010  0.787
2010 Merte J, Jensen D, Wright K, Sarsfield S, Wang Y, Schekman R, Ginty DD. Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure. Nature Cell Biology. 12: 41-6; sup pp 1-8. PMID 19966784 DOI: 10.1038/Ncb2002  0.782
2009 Luo W, Enomoto H, Rice FL, Milbrandt J, Ginty DD. Molecular identification of rapidly adapting mechanoreceptors and their developmental dependence on ret signaling. Neuron. 64: 841-56. PMID 20064391 DOI: 10.1016/J.Neuron.2009.11.003  0.653
2009 Tran TS, Rubio ME, Clem RL, Johnson D, Case L, Tessier-Lavigne M, Huganir RL, Ginty DD, Kolodkin AL. Secreted semaphorins control spine distribution and morphogenesis in the postnatal CNS. Nature. 462: 1065-9. PMID 20010807 DOI: 10.1038/Nature08628  0.633
2009 Kolk SM, Gunput RA, Tran TS, van den Heuvel DM, Prasad AA, Hellemons AJ, Adolfs Y, Ginty DD, Kolodkin AL, Burbach JP, Smidt MP, Pasterkamp RJ. Semaphorin 3F is a bifunctional guidance cue for dopaminergic axons and controls their fasciculation, channeling, rostral growth, and intracortical targeting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12542-57. PMID 19812329 DOI: 10.1523/Jneurosci.2521-09.2009  0.649
2009 Mandai K, Guo T, St Hillaire C, Meabon JS, Kanning KC, Bothwell M, Ginty DD. LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development. Neuron. 63: 614-27. PMID 19755105 DOI: 10.1016/J.Neuron.2009.07.031  0.549
2009 Mandai K, Ginty DD. Identification and characterization of molecules directing axon growth and target field innervation of somatosensory neurons Neuroscience Research. 65: S17. DOI: 10.1016/j.neures.2009.09.1579  0.401
2008 Newbern J, Zhong J, Wickramasinghe RS, Li X, Wu Y, Samuels I, Cherosky N, Karlo JC, O'Loughlin B, Wikenheiser J, Gargesha M, Doughman YQ, Charron J, Ginty DD, Watanabe M, et al. Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development. Proceedings of the National Academy of Sciences of the United States of America. 105: 17115-20. PMID 18952847 DOI: 10.1073/Pnas.0805239105  0.318
2008 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD. Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 58: 532-45. PMID 18498735 DOI: 10.1016/j.neuron.2008.03.006  0.664
2008 Makita T, Sucov HM, Gariepy CE, Yanagisawa M, Ginty DD. Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons. Nature. 452: 759-63. PMID 18401410 DOI: 10.1038/Nature06859  0.445
2008 Deppmann CD, Mihalas S, Sharma N, Lonze BE, Niebur E, Ginty DD. A model for neuronal competition during development. Science (New York, N.Y.). 320: 369-73. PMID 18323418 DOI: 10.1016/J.Ijdevneu.2008.09.036  0.806
2008 Ginty DD, Ye H, Kuruvilla R. Retrograde NGF signalling and survival in compartmentalized sympathetic neurons Journal of Neurochemistry. 81: 79-79. DOI: 10.1046/J.1471-4159.81.S1.101.X  0.781
2007 Luo W, Wickramasinghe SR, Savitt JM, Griffin JW, Dawson TM, Ginty DD. A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons. Neuron. 54: 739-54. PMID 17553423 DOI: 10.1016/J.Neuron.2007.04.027  0.771
2006 Deppmann CD, Ginty DD. Retrograde control of neural circuit formation. Cell. 127: 1306-7. PMID 17190596 DOI: 10.1016/J.Cell.2006.12.013  0.69
2006 Alvania RS, Chen X, Ginty DD. Calcium signals control Wnt-dependent dendrite growth. Neuron. 50: 813-5. PMID 16772162 DOI: 10.1016/j.neuron.2006.06.001  0.337
2006 Riccio A, Alvania RS, Lonze BE, Ramanan N, Kim T, Huang Y, Dawson TM, Snyder SH, Ginty DD. A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons. Molecular Cell. 21: 283-94. PMID 16427017 DOI: 10.1016/J.Molcel.2005.12.006  0.691
2005 Huber AB, Kania A, Tran TS, Gu C, De Marco Garcia N, Lieberam I, Johnson D, Jessell TM, Ginty DD, Kolodkin AL. Distinct roles for secreted semaphorin signaling in spinal motor axon guidance. Neuron. 48: 949-64. PMID 16364899 DOI: 10.1016/J.NEURON.2005.12.003  0.76
2005 Lee J, Kim CH, Simon DK, Aminova LR, Andreyev AY, Kushnareva YE, Murphy AN, Lonze BE, Kim KS, Ginty DD, Ferrante RJ, Ryu H, Ratan RR. Mitochondrial cyclic AMP response element-binding protein (CREB) mediates mitochondrial gene expression and neuronal survival. The Journal of Biological Chemistry. 280: 40398-401. PMID 16207717 DOI: 10.1074/Jbc.C500140200  0.616
2005 Zweifel LS, Kuruvilla R, Ginty DD. Functions and mechanisms of retrograde neurotrophin signalling. Nature Reviews. Neuroscience. 6: 615-25. PMID 16062170 DOI: 10.1038/nrn1727  0.804
2005 Glebova NO, Ginty DD. Growth and survival signals controlling sympathetic nervous system development. Annual Review of Neuroscience. 28: 191-222. PMID 16022594 DOI: 10.1146/Annurev.Neuro.28.061604.135659  0.731
2005 Valdez G, Akmentin W, Philippidou P, Kuruvilla R, Ginty DD, Halegoua S. Pincher-mediated macroendocytosis underlies retrograde signaling by neurotrophin receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5236-47. PMID 15917464 DOI: 10.1523/Jneurosci.5104-04.2005  0.725
2005 Ramanan N, Shen Y, Sarsfield S, Lemberger T, Schütz G, Linden DJ, Ginty DD. SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability. Nature Neuroscience. 8: 759-67. PMID 15880109 DOI: 10.1038/Nn1462  0.43
2005 Chen X, Ye H, Kuruvilla R, Ramanan N, Scangos KW, Zhang C, Johnson NM, England PM, Shokat KM, Ginty DD. A chemical-genetic approach to studying neurotrophin signaling. Neuron. 46: 13-21. PMID 15820690 DOI: 10.1016/J.Neuron.2005.03.009  0.773
2005 Sahay A, Kim CH, Sepkuty JP, Cho E, Huganir RL, Ginty DD, Kolodkin AL. Secreted semaphorins modulate synaptic transmission in the adult hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3613-20. PMID 15814792 DOI: 10.1523/Jneurosci.5255-04.2005  0.699
2005 Chen AE, Ginty DD, Fan CM. Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins. Nature. 433: 317-22. PMID 15568017 DOI: 10.1038/Nature03126  0.309
2005 Gu C, Yoshida Y, Livet J, Reimert DV, Mann F, Merte J, Henderson CE, Jessell TM, Kolodkin AL, Ginty DD. Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins. Science (New York, N.Y.). 307: 265-8. PMID 15550623 DOI: 10.1126/Science.1105416  0.768
2004 Schwarz Q, Gu C, Fujisawa H, Sabelko K, Gertsenstein M, Nagy A, Taniguchi M, Kolodkin AL, Ginty DD, Shima DT, Ruhrberg C. Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve. Genes & Development. 18: 2822-34. PMID 15545635 DOI: 10.1101/Gad.322904  0.786
2004 Cloutier JF, Sahay A, Chang EC, Tessier-Lavigne M, Dulac C, Kolodkin AL, Ginty DD. Differential requirements for semaphorin 3F and Slit-1 in axonal targeting, fasciculation, and segregation of olfactory sensory neuron projections. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9087-96. PMID 15483127 DOI: 10.1523/Jneurosci.2786-04.2004  0.731
2004 Kuruvilla R, Zweifel LS, Glebova NO, Lonze BE, Valdez G, Ye H, Ginty DD. A neurotrophin signaling cascade coordinates sympathetic neuron development through differential control of TrkA trafficking and retrograde signaling. Cell. 118: 243-55. PMID 15260993 DOI: 10.1016/J.Cell.2004.06.021  0.81
2004 Glebova NO, Ginty DD. Heterogeneous requirement of NGF for sympathetic target innervation in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 743-51. PMID 14736860 DOI: 10.1523/Jneurosci.4523-03.2004  0.69
2003 Sahay A, Molliver ME, Ginty DD, Kolodkin AL. Semaphorin 3F is critical for development of limbic system circuitry and is required in neurons for selective CNS axon guidance events. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 6671-80. PMID 12890759 DOI: 10.1523/Jneurosci.23-17-06671.2003  0.747
2003 Gu C, Rodriguez ER, Reimert DV, Shu T, Fritzsch B, Richards LJ, Kolodkin AL, Ginty DD. Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Developmental Cell. 5: 45-57. PMID 12852851 DOI: 10.1016/S1534-5807(03)00169-2  0.755
2003 Ye H, Kuruvilla R, Zweifel LS, Ginty DD. Evidence in support of signaling endosome-based retrograde survival of sympathetic neurons. Neuron. 39: 57-68. PMID 12848932 DOI: 10.1016/S0896-6273(03)00266-6  0.822
2003 Huber AB, Kolodkin AL, Ginty DD, Cloutier JF. Signaling at the growth cone: ligand-receptor complexes and the control of axon growth and guidance. Annual Review of Neuroscience. 26: 509-63. PMID 12677003 DOI: 10.1146/Annurev.Neuro.26.010302.081139  0.614
2002 Lonze BE, Ginty DD. Function and regulation of CREB family transcription factors in the nervous system. Neuron. 35: 605-23. PMID 12194863 DOI: 10.1016/S0896-6273(02)00828-0  0.632
2002 Ginty DD, Segal RA. Retrograde neurotrophin signaling: Trk-ing along the axon. Current Opinion in Neurobiology. 12: 268-74. PMID 12049932 DOI: 10.1016/S0959-4388(02)00326-4  0.41
2002 Lonze BE, Riccio A, Cohen S, Ginty DD. Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB. Neuron. 34: 371-85. PMID 11988169 DOI: 10.1016/S0896-6273(02)00686-4  0.769
2002 Dawson TM, Ginty DD. CREB family transcription factors inhibit neuronal suicide. Nature Medicine. 8: 450-1. PMID 11984583 DOI: 10.1038/Nm0502-450  0.366
2002 Cloutier JF, Giger RJ, Koentges G, Dulac C, Kolodkin AL, Ginty DD. Neuropilin-2 mediates axonal fasciculation, zonal segregation, but not axonal convergence, of primary accessory olfactory neurons. Neuron. 33: 877-92. PMID 11906695 DOI: 10.1016/S0896-6273(02)00635-9  0.662
2002 Gu C, Limberg BJ, Whitaker GB, Perman B, Leahy DJ, Rosenbaum JS, Ginty DD, Kolodkin AL. Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165. The Journal of Biological Chemistry. 277: 18069-76. PMID 11886873 DOI: 10.1074/Jbc.M201681200  0.726
2001 Qian X, Ginty DD. SH2-B and APS are multimeric adapters that augment TrkA signaling. Molecular and Cellular Biology. 21: 1613-20. PMID 11238898 DOI: 10.1128/Mcb.21.5.1613-1620.2001  0.549
2001 Pieper AA, Brat DJ, O'Hearn E, Krug DK, Kaplin AI, Takahashi K, Greenberg JH, Ginty D, Molliver ME, Snyder SH. Differential neuronal localizations and dynamics of phosphorylated and unphosphorylated type 1 inositol 1,4,5-trisphosphate receptors. Neuroscience. 102: 433-44. PMID 11166129 DOI: 10.1016/S0306-4522(00)00470-X  0.641
2000 Kuruvilla R, Ye H, Ginty DD. Spatially and functionally distinct roles of the PI3-K effector pathway during NGF signaling in sympathetic neurons. Neuron. 27: 499-512. PMID 11055433 DOI: 10.1016/S0896-6273(00)00061-1  0.78
2000 Sasaki M, Gonzalez-Zulueta M, Huang H, Herring WJ, Ahn S, Ginty DD, Dawson VL, Dawson TM. Dynamic regulation of neuronal NO synthase transcription by calcium influx through a CREB family transcription factor-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 97: 8617-22. PMID 10900019 DOI: 10.1073/Pnas.97.15.8617  0.563
2000 Ahn S, Riccio A, Ginty DD. Spatial considerations for stimulus-dependent transcription in neurons. Annual Review of Physiology. 62: 803-23. PMID 10845112 DOI: 10.1146/Annurev.Physiol.62.1.803  0.635
2000 Giger RJ, Cloutier JF, Sahay A, Prinjha RK, Levengood DV, Moore SE, Pickering S, Simmons D, Rastan S, Walsh FS, Kolodkin AL, Ginty DD, Geppert M. Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins. Neuron. 25: 29-41. PMID 10707970 DOI: 10.1016/S0896-6273(00)80869-7  0.716
1999 Riccio A, Ahn S, Davenport CM, Blendy JA, Ginty DD. Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons. Science (New York, N.Y.). 286: 2358-61. PMID 10600750 DOI: 10.1126/Science.286.5448.2358  0.782
1999 Tsui-Pierchala BA, Ginty DD. Characterization of an NGF-P-TrkA retrograde-signaling complex and age-dependent regulation of TrkA phosphorylation in sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8207-18. PMID 10493722 DOI: 10.1523/Jneurosci.19-19-08207.1999  0.431
1999 Ahn S, Ginty DD, Linden DJ. A late phase of cerebellar long-term depression requires activation of CaMKIV and CREB. Neuron. 23: 559-68. PMID 10433267 DOI: 10.1016/S0896-6273(00)80808-9  0.501
1999 Bamberg JA, Baumgartner S, Betz H, Bolz J, Chedotal A, Christensen CRL, Comoglio PM, Culotti JG, Doherty P, Drabkin H, Ensser A, Fishman MC, Fleckenstein B, Freeman GJ, Fujisawa H, ... ... Ginty DD, et al. Unified nomenclature for the semaphorins/collapsins [1] Cell. 97: 551-552. PMID 10367884 DOI: 10.1016/S0092-8674(00)80766-7  0.466
1998 Naruse S, Thinakaran G, Luo JJ, Kusiak JW, Tomita T, Iwatsubo T, Qian X, Ginty DD, Price DL, Borchelt DR, Wong PC, Sisodia SS. Effects of PS1 deficiency on membrane protein trafficking in neurons. Neuron. 21: 1213-21. PMID 9856475 DOI: 10.1016/S0896-6273(00)80637-6  0.595
1998 Giger RJ, Urquhart ER, Gillespie SK, Levengood DV, Ginty DD, Kolodkin AL. Neuropilin-2 is a receptor for semaphorin IV: insight into the structural basis of receptor function and specificity. Neuron. 21: 1079-92. PMID 9856463 DOI: 10.1016/S0896-6273(00)80625-X  0.584
1998 Qian X, Riccio A, Zhang Y, Ginty DD. Identification and characterization of novel substrates of Trk receptors in developing neurons. Neuron. 21: 1017-29. PMID 9856458 DOI: 10.1016/S0896-6273(00)80620-0  0.607
1998 Polleux F, Giger RJ, Ginty DD, Kolodkin AL, Ghosh A. Patterning of cortical efferent projections by semaphorin-neuropilin interactions. Science (New York, N.Y.). 282: 1904-6. PMID 9836643 DOI: 10.1126/Science.282.5395.1904  0.739
1998 Ahn S, Olive M, Aggarwal S, Krylov D, Ginty DD, Vinson C. A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fos. Molecular and Cellular Biology. 18: 967-77. PMID 9447994 DOI: 10.1128/Mcb.18.2.967  0.523
1997 Kolodkin AL, Ginty DD. Steering clear of semaphorins: neuropilins sound the retreat. Neuron. 19: 1159-62. PMID 9427240 DOI: 10.1016/S0896-6273(00)80408-0  0.515
1997 Kolodkin AL, Levengood DV, Rowe EG, Tai YT, Giger RJ, Ginty DD. Neuropilin is a semaphorin III receptor. Cell. 90: 753-62. PMID 9288754 DOI: 10.1016/S0092-8674(00)80535-8  0.639
1997 Riccio A, Pierchala BA, Ciarallo CL, Ginty DD. An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons. Science (New York, N.Y.). 277: 1097-100. PMID 9262478 DOI: 10.1126/science.277.5329.1097  0.749
1997 Ginty DD. Calcium regulation of gene expression: isn't that spatial? Neuron. 18: 183-6. PMID 9052789 DOI: 10.1016/S0896-6273(00)80258-5  0.334
1996 Kornhauser JM, Ginty DD, Greenberg ME, Mayo KE, Takahashi JS. Light entrainment and activation of signal transduction pathways in the SCN. Progress in Brain Research. 111: 133-46. PMID 8990912 DOI: 10.1016/S0079-6123(08)60405-7  0.485
1996 Xing J, Ginty DD, Greenberg ME. Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science (New York, N.Y.). 273: 959-63. PMID 8688081 DOI: 10.1126/Science.273.5277.959  0.481
1995 Thompson MA, Ginty DD, Bonni A, Greenberg ME. L-type voltage-sensitive Ca2+ channel activation regulates c-fos transcription at multiple levels. The Journal of Biological Chemistry. 270: 4224-35. PMID 7876182 DOI: 10.1074/Jbc.270.9.4224  0.643
1995 Miranti CK, Ginty DD, Huang G, Chatila T, Greenberg ME. Calcium activates serum response factor-dependent transcription by a Ras- and Elk-1-independent mechanism that involves a Ca2+/calmodulin-dependent kinase. Molecular and Cellular Biology. 15: 3672-84. PMID 7791774 DOI: 10.1128/Mcb.15.7.3672  0.476
1995 Rosen LB, Ginty DD, Greenberg ME. Calcium regulation of gene expression. Advances in Second Messenger and Phosphoprotein Research. 30: 225-53. PMID 7695991  0.356
1995 Hirata Y, Whalin M, Ginty DD, Xing J, Greenberg ME, Milbrandt J, Guroff G. Induction of a nerve growth factor-sensitive kinase that phosphorylates the DNA-binding domain of the orphan nuclear receptor NGFI-B. Journal of Neurochemistry. 65: 1780-8. PMID 7561876 DOI: 10.1046/J.1471-4159.1995.65041780.X  0.455
1995 Bonni A, Ginty DD, Dudek H, Greenberg ME. Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals. Molecular and Cellular Neurosciences. 6: 168-83. PMID 7551568 DOI: 10.1006/mcne.1995.1015  0.666
1994 Ginty DD, Bonni A, Greenberg ME. Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB. Cell. 77: 713-25. PMID 8205620 DOI: 10.1016/0092-8674(94)90055-8  0.658
1994 Rosen LB, Ginty DD, Weber MJ, Greenberg ME. Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. Neuron. 12: 1207-21. PMID 8011335 DOI: 10.1016/0896-6273(94)90438-3  0.465
1994 Ghosh A, Ginty DD, Bading H, Greenberg ME. Calcium regulation of gene expression in neuronal cells. Journal of Neurobiology. 25: 294-303. PMID 7910846 DOI: 10.1002/Neu.480250309  0.772
1993 Rivera VM, Miranti CK, Misra RP, Ginty DD, Chen RH, Blenis J, Greenberg ME. A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity. Molecular and Cellular Biology. 13: 6260-73. PMID 8413226 DOI: 10.1128/Mcb.13.10.6260  0.466
1993 Ginty DD, Kornhauser JM, Thompson MA, Bading H, Mayo KE, Takahashi JS, Greenberg ME. Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock. Science (New York, N.Y.). 260: 238-41. PMID 8097062 DOI: 10.1126/Science.8097062  0.649
1993 Bading H, Ginty DD, Greenberg ME. Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways. Science (New York, N.Y.). 260: 181-6. PMID 8097060 DOI: 10.1126/Science.8097060  0.665
1992 Glowacka D, Ginty DD, Wagner JA. Synergistic effects of nerve growth factor and phorbol 12-myristate 13-acetate on rapid motility and process formation in PC12 cells: the role of laminin. Journal of Neuroscience Research. 31: 263-72. PMID 1573676 DOI: 10.1002/jnr.490310207  0.48
1992 Ginty DD, Bading H, Greenberg ME. Trans-synaptic regulation of gene expression. Current Opinion in Neurobiology. 2: 312-6. PMID 1322751 DOI: 10.1016/0959-4388(92)90121-Z  0.651
1992 Ginty DD, Fanger GR, Wagner JA, Maue RA. The activity of cAMP-dependent protein kinase is required at a posttranslational level for induction of voltage-dependent sodium channels by peptide growth factors in PC12 cells. The Journal of Cell Biology. 116: 1465-73. PMID 1311713 DOI: 10.1083/Jcb.116.6.1465  0.448
1991 Scheibe RJ, Ginty DD, Wagner JA. Retinoic acid stimulates the differentiation of PC12 cells that are deficient in cAMP-dependent protein kinase. The Journal of Cell Biology. 113: 1173-82. PMID 1645738 DOI: 10.1083/Jcb.113.5.1173  0.436
1990 Seidel ER, Ginty DD. Apparent post-transcriptional modification of ornithine decarboxylase accounts for its induction in IEC-6 cells in culture. Digestion. 46: 383-9. PMID 2262070 DOI: 10.1159/000200412  0.597
1990 Ginty DD, Marlowe M, Pekala PH, Seidel ER. Multiple pathways for the regulation of ornithine decarboxylase in intestinal epithelial cells. The American Journal of Physiology. 258: G454-60. PMID 2107756 DOI: 10.1152/Ajpgi.1990.258.3.G454  0.607
1990 Schmidt WE, Creutzfeldt W, Höcker M, Choudhury AR, Nustede R, Schleser A, Nitsche R, Rovati LC, Schafmayer A, Fölsch UR, Young GP, Taranto TM, Jonas HA, Cox AJ, Hogg A, ... ... Ginty DD, et al. Subject Index, Vol. 46, Supplement 2, 1990 Digestion. 46: 475-477. DOI: 10.1159/000200428  0.57
1989 Ginty DD, Seidel ER. Polyamine-dependent growth and calmodulin-regulated induction of ornithine decarboxylase. The American Journal of Physiology. 256: G342-8. PMID 2493197 DOI: 10.1152/Ajpgi.1989.256.2.G342  0.603
1989 Ginty DD, Osborne DL, Seidel ER. Putrescine stimulates DNA synthesis in intestinal epithelial cells. The American Journal of Physiology. 257: G145-50. PMID 2473652 DOI: 10.1152/Ajpgi.1989.257.1.G145  0.593
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