Year |
Citation |
Score |
2023 |
Mackman RL, Kalla RV, Babusis D, Pitts J, Barrett KT, Chun K, Du Pont V, Rodriguez L, Moshiri J, Xu Y, Lee M, Lee G, Bleier B, Nguyen AQ, O'Keefe BM, et al. Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys. Journal of Medicinal Chemistry. PMID 37596939 DOI: 10.1021/acs.jmedchem.3c00750 |
0.311 |
|
2022 |
Pitts J, Li J, Perry JK, Du Pont V, Riola N, Rodriguez L, Lu X, Kurhade C, Xie X, Camus G, Manhas S, Martin R, Shi PY, Cihlar T, Porter DP, et al. Remdesivir and GS-441524 Retain Antiviral Activity against Delta, Omicron, and Other Emergent SARS-CoV-2 Variants. Antimicrobial Agents and Chemotherapy. e0022222. PMID 35532238 DOI: 10.1128/aac.00222-22 |
0.326 |
|
2021 |
Vermillion MS, Murakami E, Ma B, Pitts J, Tomkinson A, Rautiola D, Babusis D, Irshad H, Siegel D, Kim C, Zhao X, Niu C, Yang J, Gigliotti A, Kadrichu N, et al. Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection. Science Translational Medicine. eabl828. PMID 34968150 DOI: 10.1126/scitranslmed.abl8282 |
0.366 |
|
2021 |
Mackman RL, Hui HC, Perron M, Murakami E, Palmiotti C, Lee G, Stray K, Zhang L, Goyal B, Chun K, Byun D, Siegel D, Simonovich S, Du Pont V, Pitts J, et al. Prodrugs of a 1'-CN-4-Aza-7,9-dideazaadenosine -Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV. Journal of Medicinal Chemistry. PMID 33835812 DOI: 10.1021/acs.jmedchem.1c00071 |
0.442 |
|
2020 |
Koenigsberg AL, Pitts JD, Heldwein EE. Identification of Buffer Conditions for Optimal Thermostability and Solubility of Herpesviral Protein UL37 Using the Thermofluor Assay. Bio-Protocol. 10: e3662. PMID 33659332 DOI: 10.21769/BioProtoc.3662 |
0.63 |
|
2020 |
Pruijssers AJ, George AS, Schäfer A, Leist SR, Gralinksi LE, Dinnon KH, Yount BL, Agostini ML, Stevens LJ, Chappell JD, Lu X, Hughes TM, Gully K, Martinez DR, Brown AJ, ... ... Pitts J, et al. Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice. Cell Reports. 107940. PMID 32668216 DOI: 10.1016/J.Celrep.2020.107940 |
0.414 |
|
2020 |
Pruijssers AJ, George AS, Schäfer A, Leist SR, Gralinksi LE, Dinnon KH, Yount BL, Agostini ML, Stevens LJ, Chappell JD, Lu X, Hughes TM, Gully K, Martinez DR, Brown AJ, ... ... Pitts J, et al. Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice. Biorxiv : the Preprint Server For Biology. PMID 32511392 DOI: 10.1101/2020.04.27.064279 |
0.422 |
|
2019 |
Pitts J, Hsia CY, Lian W, Wang J, Pfeil MP, Kwiatkowski N, Li Z, Jang J, Gray NS, Yang PL. Identification of small molecule inhibitors targeting the Zika virus envelope protein. Antiviral Research. PMID 30771406 DOI: 10.1016/J.Antiviral.2019.02.008 |
0.793 |
|
2019 |
Li PC, Jang J, Hsia CY, Groomes P, Lian W, de Wispelaere M, Pitts JD, Wang J, Kwaitkowski N, Gray NS, Yang PL. Small molecules targeting the flavivirus E protein with broad-spectrum activity and antiviral efficacy in vivo. Acs Infectious Diseases. PMID 30608640 DOI: 10.1021/Acsinfecdis.8B00322 |
0.774 |
|
2018 |
de Wispelaere M, Lian W, Potisopon S, Li PC, Jang J, Ficarro SB, Clark MJ, Zhu X, Kaplan JB, Pitts JD, Wales TE, Wang J, Engen JR, Marto JA, Gray NS, et al. Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein. Cell Chemical Biology. PMID 29937406 DOI: 10.1016/J.Chembiol.2018.05.011 |
0.603 |
|
2017 |
Richards AL, Sollars PJ, Pitts JD, Stults AM, Heldwein EE, Pickard GE, Smith GA. The pUL37 tegument protein guides alpha-herpesvirus retrograde axonal transport to promote neuroinvasion. Plos Pathogens. 13: e1006741. PMID 29216315 DOI: 10.1371/Journal.Ppat.1006741 |
0.743 |
|
2017 |
Pitts JD, Li PC, de Wispelaere M, Yang PL. Antiviral activity of fenretinide against Zika virus. Antiviral Research. PMID 29051080 DOI: 10.1016/J.Antiviral.2017.10.014 |
0.759 |
|
2016 |
Clark MJ, Miduturu C, Schmidt AG, Zhu X, Pitts JD, Wang J, Potisopon S, Zhang J, Wojciechowski A, Hann Chu JJ, Gray NS, Yang PL. GNF-2 Inhibits Dengue Virus by Targeting Abl Kinases and the Viral E Protein. Cell Chemical Biology. 23: 443-452. PMID 27105280 DOI: 10.1016/J.Chembiol.2016.03.010 |
0.712 |
|
2014 |
Pitts JD, Klabis J, Richards AL, Smith GA, Heldwein EE. Crystal structure of the herpesvirus inner tegument protein UL37 supports its essential role in control of viral trafficking Journal of Virology. 88: 5462-5473. PMID 24599989 DOI: 10.1128/Jvi.00163-14 |
0.75 |
|
1973 |
Volkers SA, Pitts JD. Virus specific surface antigen in cells productively infected with polyoma virus. Nature: New Biology. 244: 274-5. PMID 4353942 |
0.491 |
|
1971 |
Jarrett O, Pitts JD, Whalley JM, Clason AE, Hay J. Isolation of the nucleic acid of feline leukemia virus. Virology. 43: 317-20. PMID 5101019 DOI: 10.1016/0042-6822(71)90252-2 |
0.363 |
|
1971 |
Nicholas GA, Pitts JD. Abortive infection of hamster cells by polyoma virus. The Biochemical Journal. 124: 45P. PMID 4331850 |
0.465 |
|
1968 |
Smart ME, House W, Pitts JD. Immunological evidence for the absence of a polyoma virus-specific deoxyribonucleic acid polymerase. The Biochemical Journal. 110: 48P-49P. PMID 4303060 |
0.428 |
|
1968 |
Beard P, Pitts JD. A polynucleotide ligase from polyoma virus-infected mouse cells. The Biochemical Journal. 110: 48P. PMID 4303059 |
0.47 |
|
1968 |
Fried M, Pitts JD. Replication of polyoma virus DNA. I. A resting cell system for biochemical studies on polyoma virus. Virology. 34: 761-70. PMID 4299116 DOI: 10.1016/0042-6822(68)90097-4 |
0.486 |
|
1967 |
Smart ME, Fried AM, Pitts JD. Polyoma-virus-induced deoxyribonucleic acid polymerase activity in resting mouse-embryo cells. The Biochemical Journal. 104: 29P. PMID 4292771 |
0.369 |
|
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