Leonid Gaidukov, Ph.D. - Publications

Affiliations: 
2007 Weizmann Institute of Science, Rehovot, Israel 
Area:
Molecular Biology

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Gaidukov L, Viji RI, Yacobson S, Rosenblat M, Aviram M, Tawfik DS. ApoE induces serum paraoxonase PON1 activity and stability similar to ApoA-I. Biochemistry. 49: 532-8. PMID 20025294 DOI: 10.1021/Bi9013227  0.624
2009 Gaidukov L, Bar D, Yacobson S, Naftali E, Kaufman O, Tabakman R, Tawfik DS, Levy-Nissenbaum E. In vivo administration of BL-3050: highly stable engineered PON1-HDL complexes. Bmc Clinical Pharmacology. 9: 18. PMID 19922610 DOI: 10.1186/1472-6904-9-18  0.555
2007 Gaidukov L, Tawfik DS. The development of human sera tests for HDL-bound serum PON1 and its lipolactonase activity. Journal of Lipid Research. 48: 1637-46. PMID 17435182 DOI: 10.1194/Jlr.D600045-Jlr200  0.587
2006 Gaidukov L, Rosenblat M, Aviram M, Tawfik DS. The 192R/Q polymorphs of serum paraoxonase PON1 differ in HDL binding, lipolactonase stimulation, and cholesterol efflux. Journal of Lipid Research. 47: 2492-502. PMID 16914770 DOI: 10.1194/Jlr.M600297-Jlr200  0.578
2006 Amitai G, Gaidukov L, Adani R, Yishay S, Yacov G, Kushnir M, Teitlboim S, Lindenbaum M, Bel P, Khersonsky O, Tawfik DS, Meshulam H. Enhanced stereoselective hydrolysis of toxic organophosphates by directly evolved variants of mammalian serum paraoxonase. The Febs Journal. 273: 1906-19. PMID 16640555 DOI: 10.1111/J.1742-4658.2006.05198.X  0.526
2006 Rosenblat M, Gaidukov L, Khersonsky O, Vaya J, Oren R, Tawfik DS, Aviram M. The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux. The Journal of Biological Chemistry. 281: 7657-65. PMID 16407304 DOI: 10.1074/Jbc.M512595200  0.58
2006 Sussman J, Aharoni A, Harel M, Gaidukov L, Brumshtein B, Khersonsky O, Yagur S, Toker L, Silman I, Tawfik D. 3D structure of mammalian paraoxonase at 2.2Å resolution Toxicology Letters. 164: S9. DOI: 10.1016/J.Toxlet.2006.06.024  0.455
2005 Gaidukov L, Tawfik DS. High affinity, stability, and lactonase activity of serum paraoxonase PON1 anchored on HDL with ApoA-I. Biochemistry. 44: 11843-54. PMID 16128586 DOI: 10.1021/Bi050862I  0.609
2005 Aharoni A, Gaidukov L, Khersonsky O, McQ Gould S, Roodveldt C, Tawfik DS. The 'evolvability' of promiscuous protein functions. Nature Genetics. 37: 73-6. PMID 15568024 DOI: 10.1038/Ng1482  0.467
2004 Harel M, Aharoni A, Gaidukov L, Brumshtein B, Khersonsky O, Meged R, Dvir H, Ravelli RB, McCarthy A, Toker L, Silman I, Sussman JL, Tawfik DS. Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes. Nature Structural & Molecular Biology. 11: 412-9. PMID 15098021 DOI: 10.1038/Nsmb767  0.59
2004 Aharoni A, Gaidukov L, Yagur S, Toker L, Silman I, Tawfik DS. Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization. Proceedings of the National Academy of Sciences of the United States of America. 101: 482-7. PMID 14695884 DOI: 10.1073/Pnas.2536901100  0.571
2004 Harel M, Aharoni A, Gaidukov L, Brumshtein B, Khersonsky O, Meged R, Dvir H, Ravelli RBG, McCarthy A, Toker L, Silman I, Sussman JL, Tawfik DS. Erratum: Corrigendum: Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes Nature Structural & Molecular Biology. 11: 1253-1253. DOI: 10.1038/Nsmb1204-1253A  0.569
2002 Kustanovich I, Shalev DE, Mikhlin M, Gaidukov L, Mor A. Structural requirements for potent versus selective cytotoxicity for antimicrobial dermaseptin S4 derivatives. The Journal of Biological Chemistry. 277: 16941-51. PMID 11847217 DOI: 10.1074/Jbc.M111071200  0.334
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