Madhavika N. Serasinghe, Ph.D. - Publications

Affiliations: 
2009 University of Rochester, Rochester, NY 
Area:
Cell Biology, Molecular Biology, Biochemistry

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Elkholi R, Abraham-Enachescu I, Trotta AP, Rubio-Patiño C, Mohammed JN, Luna-Vargas MPA, Gelles JD, Kaminetsky JR, Serasinghe MN, Zou C, Ali S, McStay GP, Pfleger CM, Chipuk JE. MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network. Molecular Cell. PMID 30879903 DOI: 10.1016/J.Molcel.2019.02.012  0.505
2018 Abbate F, Badal B, Mendelson K, Aydin IT, Serasinghe MN, Iqbal R, Mohammed J, Solovyov A, Greenbaum BD, Chipuk JE, Celebi JT. FBXW7 regulates a mitochondrial transcription program by modulating MITF. Pigment Cell & Melanoma Research. PMID 29665239 DOI: 10.1111/Pcmr.12704  0.428
2018 Serasinghe MN, Gelles JD, Li K, Zhao L, Abbate F, Syku M, Mohammed JN, Badal B, Rangel CA, Hoehn KL, Celebi JT, Chipuk JE. Dual suppression of inner and outer mitochondrial membrane functions augments apoptotic responses to oncogenic MAPK inhibition. Cell Death & Disease. 9: 29. PMID 29348439 DOI: 10.1038/S41419-017-0044-1  0.492
2017 Hogstad B, Berres ML, Chakraborty R, Tang J, Bigenwald C, Serasinghe M, Lim KPH, Lin H, Man TK, Remark R, Baxter S, Kana V, Jordan S, Karoulia Z, Kwan WH, et al. RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions. The Journal of Experimental Medicine. PMID 29263218 DOI: 10.1084/Jem.20161881  0.301
2017 Trotta AP, Gelles JD, Serasinghe MN, Loi P, Arbiser JL, Chipuk JE. Disruption of mitochondrial electron transport chain function potentiates the pro-apoptotic effects of MAPK inhibition. The Journal of Biological Chemistry. PMID 28546431 DOI: 10.1074/Jbc.M117.786442  0.493
2017 Serasinghe MN, Chipuk JE. Mitochondrial Fission in Human Diseases. Handbook of Experimental Pharmacology. PMID 28040850 DOI: 10.1007/164_2016_38  0.46
2015 Rimmelé P, Liang R, Bigarella CL, Kocabas F, Xie J, Serasinghe MN, Chipuk J, Sadek H, Zhang CC, Ghaffari S. Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3. Embo Reports. PMID 26209246 DOI: 10.15252/Embr.201439704  0.404
2015 Gelles JD, Elkholi R, Serasinghe MN, Luna-Vargas MP, Chipuk JE. From zero to sixty: cell death signaling in the city that never sleeps. Oncogene. PMID 26148239 DOI: 10.1038/Onc.2015.194  0.379
2015 Wieder SY, Serasinghe MN, Sung JC, Choi DC, Birge MB, Yao JL, Bernstein E, Celebi JT, Chipuk JE. Activation of the Mitochondrial Fragmentation Protein DRP1 Correlates with BRAF(V600E) Melanoma. The Journal of Investigative Dermatology. PMID 26032958 DOI: 10.1038/Jid.2015.196  0.337
2015 Serasinghe MN, Wieder SY, Renault TT, Elkholi R, Asciolla JJ, Yao JL, Jabado O, Hoehn K, Kageyama Y, Sesaki H, Chipuk JE. Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors. Molecular Cell. 57: 521-36. PMID 25658204 DOI: 10.1016/J.Molcel.2015.01.003  0.48
2015 Renault TT, Floros KV, Elkholi R, Corrigan KA, Kushnareva Y, Wieder SY, Lindtner C, Serasinghe MN, Asciolla JJ, Buettner C, Newmeyer DD, Chipuk JE. Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis. Molecular Cell. 57: 69-82. PMID 25482509 DOI: 10.1016/J.Molcel.2014.10.028  0.494
2014 Elkholi R, Renault TT, Serasinghe MN, Chipuk JE. Putting the pieces together: How is the mitochondrial pathway of apoptosis regulated in cancer and chemotherapy? Cancer & Metabolism. 2: 16. PMID 25621172 DOI: 10.1186/2049-3002-2-16  0.409
2014 Serasinghe MN, Missert DJ, Asciolla JJ, Podgrabinska S, Wieder SY, Izadmehr S, Belbin G, Skobe M, Chipuk JE. Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAFV600E inhibition and can be targeted to reduce resistance Oncogene. DOI: 10.1038/Onc.2014.21  0.389
2010 Serasinghe MN, Seneviratne AM, Smrcka AV, Yoon Y. Identification and characterization of unique proline-rich peptides binding to the mitochondrial fission protein hFis1. The Journal of Biological Chemistry. 285: 620-30. PMID 19864424 DOI: 10.1074/Jbc.M109.027508  0.524
2008 Serasinghe MN, Yoon Y. The mitochondrial outer membrane protein hFis1 regulates mitochondrial morphology and fission through self-interaction. Experimental Cell Research. 314: 3494-507. PMID 18845145 DOI: 10.1016/J.Yexcr.2008.09.009  0.564
Show low-probability matches.