William M. Erwin, Ph.D. - Publications

Affiliations: 
2004 University of Toronto, Toronto, ON, Canada 
Area:
Molecular Biology, Animal Physiology Biology

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Matta A, Erwin WM. Current Status of the Instructional Cues Provided by Notochordal Cells in Novel Disc Repair Strategies. International Journal of Molecular Sciences. 23. PMID 35008853 DOI: 10.3390/ijms23010427  0.376
2020 Matta A, Karim MZ, Gerami H, Benigno BZ, Erwin WM. 213. Study comparing NTG-101, a growth factor-based therapy with mesenchymal stem cell (MSC) based treatment of degenerative disc disease (DDD) in pre-clinical rodent model The Spine Journal. 20. DOI: 10.1016/J.Spinee.2020.05.624  0.36
2019 Erwin WM, Matta A, Karim MZ, Gerami H. 122. Cartilage derived stem cells: a novel cellular replacement therapy to treat degenerative disc disease The Spine Journal. 19: S59-S60. DOI: 10.1016/J.Spinee.2019.05.136  0.403
2018 Erwin WM, Matta A, Karim MZ, Gerami H, Goldstein AV, Foltz W, Sussman MS, Jun PY, Funabashi M, Kawchuk GN, Eek B. Thursday, September 27, 2018 2:05 PM–3:05 PM Section on Biologics and Basic Research Abstract Presentations The Spine Journal. 18: S61-S62. DOI: 10.1016/J.Spinee.2018.06.390  0.389
2017 Matta A, Karim MZ, Isenman DE, Erwin WM. Molecular Therapy for Degenerative Disc Disease: Clues from Secretome Analysis of the Notochordal Cell-Rich Nucleus Pulposus. Scientific Reports. 7: 45623. PMID 28358123 DOI: 10.1038/srep45623  0.359
2017 Mehrkens A, Matta A, Karim MZ, Kim S, Fehlings MG, Schaeren S, Erwin WM. Notochordal cell-derived conditioned medium (NCCM) protects human nucleus pulposus cells from stress-induced apoptosis. The Spine Journal : Official Journal of the North American Spine Society. PMID 28089818 DOI: 10.1016/J.Spinee.2017.01.003  0.377
2016 Müller S, Acevedo L, Wang X, Karim MZ, Matta A, Mehrkens A, Schaeren S, Feliciano S, Jakob M, Martin I, Barbero A, Erwin WM. Notochordal cell conditioned medium (NCCM) regenerates end-stage human osteoarthritic articular chondrocytes and promotes a healthy phenotype. Arthritis Research & Therapy. 18: 125. PMID 27255741 DOI: 10.1186/s13075-016-1026-x  0.309
2016 Matta A, Karim MZ, Isenman D, Erwin WM. Notochordal Cell-Based Therapeutics Can Regenerate the Degenerative Disc The Spine Journal. 16: S225. DOI: 10.1016/J.Spinee.2016.07.134  0.406
2015 Erwin WM, DeSouza L, Funabashi M, Kawchuk G, Karim MZ, Kim S, Mӓdler S, Matta A, Wang X, Mehrkens KA. The biological basis of degenerative disc disease: proteomic and biomechanical analysis of the canine intervertebral disc. Arthritis Research & Therapy. 17: 240. PMID 26341258 DOI: 10.1186/S13075-015-0733-Z  0.318
2013 Mehrkens A, Karim MZ, Kim S, Hilario R, Fehlings MG, Erwin WM. Canine notochordal cell-secreted factors protect murine and human nucleus pulposus cells from apoptosis by inhibition of activated caspase-9 and caspase-3/7. Evidence-Based Spine-Care Journal. 4: 154-6. PMID 24436715 DOI: 10.1055/S-0033-1357363  0.394
2013 Erwin WM, Islam D, Eftekarpour E, Inman RD, Karim MZ, Fehlings MG. Intervertebral disc-derived stem cells: implications for regenerative medicine and neural repair. Spine. 38: 211-6. PMID 22772571 DOI: 10.1097/Brs.0B013E318266A80D  0.478
2012 Erwin WM, Islam D, Davies-Inman R, Fehlings MG, Tsui FW. Notochordal Cells Protect Nucleus Pulposus Cells from Apoptosis: Implications for the Mechanisms of Intervertebral Disc Degeneration The Spine Journal. 12: S43. DOI: 10.1016/J.Spinee.2012.08.127  0.308
2011 Erwin WM, Islam D, Inman RD, Fehlings MG, Tsui FW. Notochordal cells protect nucleus pulposus cells from degradation and apoptosis: implications for the mechanisms of intervertebral disc degeneration. Arthritis Research & Therapy. 13: R215. PMID 22206702 DOI: 10.1055/S-0032-1319928  0.504
2011 Las Heras F, DaCosta RS, Pritzker KP, Haroon N, Netchev G, Tsui HW, Chiu B, Erwin WM, Tsui FW, Inman RD. Aberrant axial mineralization precedes spinal ankylosis: a molecular imaging study in ank/ank mice. Arthritis Research & Therapy. 13: R163. PMID 21992149 DOI: 10.1186/Ar3482  0.48
2010 Erwin WM. The enigma that is the nucleus pulposus cell: the search goes on. Arthritis Research & Therapy. 12: 118. PMID 20587085 DOI: 10.1186/ar3001  0.329
2009 Erwin WM, Las Heras F, Islam D, Fehlings MG, Inman RD. The regenerative capacity of the notochordal cell: tissue constructs generated in vitro under hypoxic conditions. Journal of Neurosurgery. Spine. 10: 513-21. PMID 19558283 DOI: 10.3171/2009.2.Spine08578  0.484
2008 Erwin WM. The Notochord, Notochordal cell and CTGF/CCN-2: ongoing activity from development through maturation. Journal of Cell Communication and Signaling. 2: 59-65. PMID 19003520 DOI: 10.1007/s12079-008-0031-5  0.34
2006 Erwin WM, Ashman K, O'Donnel P, Inman RD. Nucleus pulposus notochord cells secrete connective tissue growth factor and up-regulate proteoglycan expression by intervertebral disc chondrocytes. Arthritis and Rheumatism. 54: 3859-67. PMID 17136753 DOI: 10.1002/Art.22258  0.444
2006 Erwin WM, Inman RD. Notochord cells regulate intervertebral disc chondrocyte proteoglycan production and cell proliferation. Spine. 31: 1094-9. PMID 16648742 DOI: 10.1097/01.Brs.0000216593.97157.Dd  0.467
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