Year |
Citation |
Score |
2020 |
Carbone M, Arron ST, Beutler B, Bononi A, Cavenee W, Cleaver JE, Croce CM, D'Andrea A, Foulkes WD, Gaudino G, Groden JL, Henske EP, Hickson ID, Hwang PM, Kolodner RD, et al. Tumour predisposition and cancer syndromes as models to study gene-environment interactions. Nature Reviews. Cancer. PMID 32472073 DOI: 10.1038/S41568-020-0265-Y |
0.353 |
|
2018 |
Behnfeldt JH, Acharya S, Tangeman L, Gocha AS, Keirsey J, Groden J. A tri-serine cluster within the topoisomerase IIα-interaction domain of the BLM helicase is required for regulating chromosome breakage in human cells. Human Molecular Genetics. PMID 29385443 DOI: 10.1093/hmg/ddy038 |
0.328 |
|
2018 |
Hankey W, Frankel WL, Groden J. Functions of the APC tumor suppressor protein dependent and independent of canonical WNT signaling: implications for therapeutic targeting. Cancer Metastasis Reviews. PMID 29318445 DOI: 10.1007/s10555-017-9725-6 |
0.324 |
|
2017 |
Martinez AR, Kaul Z, Parvin JD, Groden J. Differential requirements for DNA repair proteins in immortalized cell lines using alternative lengthening of telomere mechanisms. Genes, Chromosomes & Cancer. PMID 28398700 DOI: 10.1002/gcc.22465 |
0.356 |
|
2015 |
McIlhatton MA, Murnan K, Carson D, Boivin GP, Croce CM, Groden J. Genetic Manipulation of Homologous Recombination In Vivo Attenuates Intestinal Tumorigenesis. Cancer Prevention Research (Philadelphia, Pa.). 8: 650-6. PMID 25908507 DOI: 10.1158/1940-6207.Capr-15-0001-T |
0.39 |
|
2014 |
Acharya S, Kaul Z, Gocha AS, Martinez AR, Harris J, Parvin JD, Groden J. Association of BLM and BRCA1 during Telomere Maintenance in ALT Cells. Plos One. 9: e103819. PMID 25084169 DOI: 10.1371/journal.pone.0103819 |
0.478 |
|
2014 |
Gocha AR, Acharya S, Groden J. WRN loss induces switching of telomerase-independent mechanisms of telomere elongation. Plos One. 9: e93991. PMID 24709898 DOI: 10.1371/journal.pone.0093991 |
0.342 |
|
2013 |
Amunugama R, Groden J, Fishel R. The HsRAD51B-HsRAD51C stabilizes the HsRAD51 nucleoprotein filament. Dna Repair. 12: 723-32. PMID 23810717 DOI: 10.1016/J.Dnarep.2013.05.005 |
0.31 |
|
2013 |
Grierson PM, Acharya S, Groden J. Collaborating functions of BLM and DNA topoisomerase I in regulating human rDNA transcription. Mutation Research. 743: 89-96. PMID 23261817 DOI: 10.1016/j.mrfmmm.2012.12.002 |
0.385 |
|
2013 |
Gocha AR, Harris J, Groden J. Alternative mechanisms of telomere lengthening: permissive mutations, DNA repair proteins and tumorigenic progression. Mutation Research. 743: 142-50. PMID 23219603 DOI: 10.1016/j.mrfmmm.2012.11.006 |
0.428 |
|
2013 |
Hankey W, Groden J. The genetics of colorectal cancer Molecular Pathogenesis of Colorectal Cancer. 1-24. DOI: 10.1007/978-1-4614-8412-7_1 |
0.306 |
|
2011 |
Perchiniak EM, Groden J. Mechanisms Regulating Microtubule Binding, DNA Replication, and Apoptosis are Controlled by the Intestinal Tumor Suppressor APC. Current Colorectal Cancer Reports. 7: 145-151. PMID 23308069 DOI: 10.1007/s11888-011-0088-z |
0.337 |
|
2011 |
Russell B, Bhattacharyya S, Keirsey J, Sandy A, Grierson P, Perchiniak E, Kavecansky J, Acharya S, Groden J. Chromosome breakage is regulated by the interaction of the BLM helicase and topoisomerase IIalpha. Cancer Research. 71: 561-71. PMID 21224348 DOI: 10.1158/0008-5472.Can-10-1727 |
0.623 |
|
2010 |
Bhattacharyya S, Sandy A, Groden J. Unwinding protein complexes in ALTernative telomere maintenance. Journal of Cellular Biochemistry. 109: 7-15. PMID 19911388 DOI: 10.1002/jcb.22388 |
0.437 |
|
2009 |
Bhattacharyya S, Keirsey J, Russell B, Kavecansky J, Lillard-Wetherell K, Tahmaseb K, Turchi JJ, Groden J. Telomerase-associated protein 1, HSP90, and topoisomerase IIalpha associate directly with the BLM helicase in immortalized cells using ALT and modulate its helicase activity using telomeric DNA substrates. The Journal of Biological Chemistry. 284: 14966-77. PMID 19329795 DOI: 10.1074/Jbc.M900195200 |
0.76 |
|
2008 |
Qian J, Sarnaik AA, Bonney TM, Keirsey J, Combs KA, Steigerwald K, Acharya S, Behbehani GK, Barton MC, Lowy AM, Groden J. The APC tumor suppressor inhibits DNA replication by directly binding to DNA via its carboxyl terminus. Gastroenterology. 135: 152-62. PMID 18474248 DOI: 10.1053/J.Gastro.2008.03.074 |
0.316 |
|
2006 |
Machwe A, Xiao L, Groden J, Orren DK. The Werner and Bloom syndrome proteins catalyze regression of a model replication fork. Biochemistry. 45: 13939-46. PMID 17115688 DOI: 10.1021/Bi0615487 |
0.482 |
|
2005 |
Lillard-Wetherell K, Combs KA, Groden J. BLM helicase complements disrupted type II telomere lengthening in telomerase-negative sgs1 yeast. Cancer Research. 65: 5520-2. PMID 15994923 DOI: 10.1158/0008-5472.Can-05-0632 |
0.766 |
|
2005 |
Machwe A, Xiao L, Groden J, Matson SW, Orren DK. RecQ family members combine strand pairing and unwinding activities to catalyze strand exchange. The Journal of Biological Chemistry. 280: 23397-407. PMID 15845538 DOI: 10.1074/Jbc.M414130200 |
0.487 |
|
2005 |
Steigerwald K, Behbehani GK, Combs KA, Barton MC, Groden J. The APC tumor suppressor promotes transcription-independent apoptosis in vitro. Molecular Cancer Research : McR. 3: 78-89. PMID 15755874 DOI: 10.1158/1541-7786.Mcr-03-0189 |
0.315 |
|
2005 |
Slupianek A, Gurdek E, Koptyra M, Nowicki MO, Siddiqui KM, Groden J, Skorski T. BLM helicase is activated in BCR/ABL leukemia cells to modulate responses to cisplatin. Oncogene. 24: 3914-22. PMID 15750625 DOI: 10.1038/Sj.Onc.1208545 |
0.496 |
|
2004 |
Risinger MA, Groden J. Crosslinks and crosstalk: human cancer syndromes and DNA repair defects. Cancer Cell. 6: 539-45. PMID 15607958 DOI: 10.1016/J.Ccr.2004.12.001 |
0.478 |
|
2004 |
Carson DJ, Santoro IM, Groden J. Isoforms of the APC tumor suppressor and their ability to inhibit cell growth and tumorigenicity. Oncogene. 23: 7144-8. PMID 15273719 DOI: 10.1038/Sj.Onc.1207954 |
0.405 |
|
2004 |
Lillard-Wetherell K, Machwe A, Langland GT, Combs KA, Behbehani GK, Schonberg SA, German J, Turchi JJ, Orren DK, Groden J. Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2. Human Molecular Genetics. 13: 1919-32. PMID 15229185 DOI: 10.1093/Hmg/Ddh193 |
0.691 |
|
2003 |
Clements WM, Lowy AM, Groden J. Adenomatous polyposis coli/beta-catenin interaction and downstream targets: altered gene expression in gastrointestinal tumors. Clinical Colorectal Cancer. 3: 113-20. PMID 12952568 DOI: 10.3816/Ccc.2003.N.018 |
0.365 |
|
2002 |
Goss KH, Risinger MA, Kordich JJ, Sanz MM, Straughen JE, Slovek LE, Capobianco AJ, German J, Boivin GP, Groden J. Enhanced tumor formation in mice heterozygous for Blm mutation. Science (New York, N.Y.). 297: 2051-3. PMID 12242442 DOI: 10.1126/Science.1074340 |
0.742 |
|
2002 |
Heppner Goss K, Trzepacz C, Tuohy TM, Groden J. Attenuated APC alleles produce functional protein from internal translation initiation. Proceedings of the National Academy of Sciences of the United States of America. 99: 8161-6. PMID 12034871 DOI: 10.1073/pnas.112072199 |
0.302 |
|
2002 |
Langland G, Elliott J, Li Y, Creaney J, Dixon K, Groden J. The BLM helicase is necessary for normal DNA double-strand break repair. Cancer Research. 62: 2766-70. PMID 12019152 |
0.758 |
|
2001 |
Lowy AM, Kordich JJ, Gismondi V, Varesco L, Blough RI, Groden J. Numerous colonic adenomas in an individual with Bloom's syndrome Gastroenterology. 121: 435-439. PMID 11487553 DOI: 10.1053/Gast.2001.26259 |
0.392 |
|
2001 |
Steigerwald K, Santoro IM, Kordich JJ, Gismondi V, Trzepacz C, Badiali M, Giangaspero F, Balko MG, Graham JS, Ratner N, Lowy AM, Varesco L, Groden J. A distinct splice form of APC is highly expressed in neurones but not commonly mutated in neuroepithelial tumours. Journal of Medical Genetics. 38: 257-62. PMID 11370631 DOI: 10.1136/Jmg.38.4.257 |
0.377 |
|
2001 |
Langland G, Kordich J, Creaney J, Goss KH, Lillard-Wetherell K, Bebenek K, Kunkel TA, Groden J. The Bloom's syndrome protein (BLM) interacts with MLH1 but is not required for DNA mismatch repair. The Journal of Biological Chemistry. 276: 30031-5. PMID 11325959 DOI: 10.1074/Jbc.M009664200 |
0.797 |
|
2000 |
Meng JJ, Lowrie DJ, Sun H, Dorsey E, Pelton PD, Bashour AM, Groden J, Ratner N, Ip W. Interaction between two isoforms of the NF2 tumor suppressor protein, merlin, and between merlin and ezrin, suggests modulation of ERM proteins by merlin. Journal of Neuroscience Research. 62: 491-502. PMID 11070492 DOI: 10.1002/1097-4547(20001115)62:4<491::Aid-Jnr3>3.0.Co;2-D |
0.338 |
|
2000 |
Steinbrecher KA, Tuohy TMF, Heppner Goss K, Scott MC, Witte DP, Groden J, Cohen MB. Expression of guanylin is downregulated in mouse and human intestinal adenomas Biochemical and Biophysical Research Communications. 273: 225-230. PMID 10873591 DOI: 10.1006/Bbrc.2000.2917 |
0.356 |
|
2000 |
Goss KH, Groden J. Biology of the adenomatous polyposis coli tumor suppressor Journal of Clinical Oncology. 18: 1967-1979. PMID 10784639 DOI: 10.1200/Jco.2000.18.9.1967 |
0.414 |
|
1999 |
Spirio L, Green J, Green R, Robertson J, Robertson M, Otterud B, Sheldon J, Howse E, Groden J, White R, Leppert M. The identical 5' splice-site acceptor mutation in five attenuated APC families from Newfoundland demonstrates a founder effect Human Genetics. 105: 388-398. PMID 10598803 DOI: 10.1007/S004390051121 |
0.386 |
|
1999 |
Presciuttini S, Gismondi V, Scarcello E, Sala P, D'Elia F, Rossetti C, Caroti-Ghelli C, Molina F, Groden J, Mosca F, Bertario L, Varesco L. Different expressivity of two adjacent mutations of the APC gene Tumori. 85: 28-31. PMID 10228493 DOI: 10.1177/030089169908500106 |
0.341 |
|
1998 |
Shahrabani-Gargir L, Shomrat R, Yaron Y, Orr-Urtreger A, Groden J, Legum C. High frequency of a common bloom syndrome Ashkenazi mutation among Jews of polish origin Genetic Testing. 2: 293-296. PMID 10464606 |
0.3 |
|
1998 |
Ellis NA, Ciocci S, Proytcheva M, Lennon D, Groden J, German J. The Ashkenazic Jewish bloom syndrome mutation blm(Ash) is present in non-Jewish Americans of Spanish ancestry American Journal of Human Genetics. 63: 1685-1693. PMID 9837821 DOI: 10.1086/302167 |
0.392 |
|
1998 |
Tuohy TMF, Groden J. Exons - Introns = Lexons: In-frame concatenation of exons by PCR Human Mutation. 12: 122-127. PMID 9671273 DOI: 10.1002/(Sici)1098-1004(1998)12:2<122::Aid-Humu7>3.0.Co;2-W |
0.4 |
|
1998 |
Gismondi V, Stagnaro P, Pedemonte S, Biticchi R, Presciuttini S, Grammatico P, Sala P, Bertario L, Groden J, Varesco L. Chain-terminating mutations in the APC gene lead to alterations in APC RNA and protein concentration Genes Chromosomes and Cancer. 22: 278-286. PMID 9669665 DOI: 10.1002/(Sici)1098-2264(199808)22:4<278::Aid-Gcc3>3.0.Co;2-S |
0.396 |
|
1998 |
Pedemonte S, Sciallero S, Gismondi V, Stagnaro P, Biticchi R, Haeouaine A, Bonelli L, Nicolo G, Groden J, Bruzzi P, Aste H, Varesco L. Novel germline APC variants in patients with multiple adenomas Genes Chromosomes and Cancer. 22: 257-267. PMID 9669663 DOI: 10.1002/(Sici)1098-2264(199808)22:4<257::Aid-Gcc1>3.0.Co;2-U |
0.392 |
|
1998 |
Straughen JE, Johnson J, McLaren D, Proytcheva M, Ellis N, German J, Groden J. A rapid method for detecting the predominant Ashkenazi Jewish mutation in the Bloom's syndrome gene. Human Mutation. 11: 175-8. PMID 9482582 DOI: 10.1002/(Sici)1098-1004(1998)11:2<175::Aid-Humu11>3.0.Co;2-W |
0.771 |
|
1998 |
Pyles RB, Santoro IM, Groden J, Parysek LM. Novel protein isoforms of the APC tumor suppressor in neural tissue Oncogene. 16: 77-82. PMID 9467945 DOI: 10.1038/Sj.Onc.1201505 |
0.336 |
|
1997 |
Trzepacz C, Lowy AM, Kordich JJ, Groden J. Phosphorylation of the tumor suppressor adenomatous polyposis coil (APC) by the cyclin-dependent kinase p34(cdc2) Journal of Biological Chemistry. 272: 21681-21684. PMID 9268294 DOI: 10.1074/Jbc.272.35.21681 |
0.375 |
|
1997 |
Heinen CD, Noffsinger AE, Belli J, Straughen J, Fischer J, Groden J, Fenoglio-Preiser CM. Regenerative lesions in ulcerative colitis are characterized by microsatellite mutation Genes Chromosomes and Cancer. 19: 170-175. PMID 9218998 DOI: 10.1002/(Sici)1098-2264(199707)19:3<170::Aid-Gcc6>3.0.Co;2-V |
0.769 |
|
1997 |
Gismondi V, Bafico A, Biticchi R, Pedemonte S, Molina F, Heouaine A, Sala P, Bertario L, Presciuttini S, Strigini P, Groden J, Varesco L. Characterization of 19 novel and six recurring APC mutations in Italian adenomatous polyposis patients, using two different mutation detection techniques Human Mutation. 9: 370-373. PMID 9101302 DOI: 10.1002/(Sici)1098-1004(1997)9:4<370::Aid-Humu14>3.0.Co;2-# |
0.332 |
|
1996 |
Heinen CD, Shivapurkar N, Tang Z, Groden J, Alabaster O. Microsatellite instability in aberrant crypt foci from human colons Cancer Research. 56: 5339-5341. PMID 8968080 |
0.369 |
|
1996 |
Straughen J, Ciocci S, Ye TZ, Lennon DN, Proytcheva M, Alhadeff B, Goodfellow P, German J, Ellis NA, Groden J. Physical mapping of the Bloom syndrome region by the identification of YAC and P1 clones from human chromosome 15 band q26.1 Genomics. 35: 118-128. PMID 8661112 DOI: 10.1006/Geno.1996.0330 |
0.741 |
|
1996 |
Kutchera W, Jones DA, Matsunami N, Groden J, McIntyre TM, Zimmerman GA, White RL, Prescott SM. Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: evidence for a transcriptional effect. Proceedings of the National Academy of Sciences of the United States of America. 93: 4816-20. PMID 8643486 DOI: 10.1073/Pnas.93.10.4816 |
0.305 |
|
1995 |
Ellis NA, Groden J, Ye TZ, Straughen J, Lennon DJ, Ciocci S, Proytcheva M, German J. The Bloom's syndrome gene product is homologous to RecQ helicases Cell. 83: 655-666. PMID 7585968 DOI: 10.1016/0092-8674(95)90105-1 |
0.767 |
|
1995 |
Heinen CD, Richardson D, White R, Groden J. Microsatellite instability in colorectal adenocarcinoma cell lines that have full-length adenomatous polyposis coli protein Cancer Research. 55: 4797-4799. PMID 7585508 |
0.328 |
|
1993 |
Varesco L, Gismondi V, James R, Robertson M, Grammatico P, Groden J, Casarino L, De Benedetti L, Bafico A, Bertario L, Sala R, Sassatelli R, Ponz De Leon M, Biasco G, Allegretti A, et al. Identification of APC gene mutations in Italian adenomatous polyposis coli patients by PCR-SSCP analysis American Journal of Human Genetics. 52: 280-285. PMID 8381581 |
0.329 |
|
1991 |
Groden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, Albertsen H, Joslyn G, Stevens J, Spirio L, Robertson M. Identification and characterization of the familial adenomatous polyposis coli gene. Cell. 66: 589-600. PMID 1651174 DOI: 10.1016/0092-8674(81)90021-0 |
0.331 |
|
1990 |
Groden J, Nakamura Y, German J. Molecular evidence that homologous recombination occurs in prolerating human somatic cells Proceedings of the National Academy of Sciences of the United States of America. 87: 4315-4319. PMID 1971948 |
0.344 |
|
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