| Year |
Citation |
Score |
| 2023 |
Lu J, Rahman MI, Kazan IC, Halloran NR, Bobkov AA, Ozkan SB, Ghirlanda G. Engineering gain-of-function mutants of a WW domain by dynamics and structural analysis. Protein Science : a Publication of the Protein Society. e4759. PMID 37574787 DOI: 10.1002/pro.4759 |
0.342 |
|
| 2020 |
Dong M, Harikumar KG, Raval SR, Milburn JE, Clark C, Alcala-Torano R, Mobarec JC, Reynolds CA, Ghirlanda G, Christopoulos A, Wootten D, Sexton PM, Miller LJ. Rational development of a high-affinity secretin receptor antagonist. Biochemical Pharmacology. 113929. PMID 32217097 DOI: 10.1016/J.Bcp.2020.113929 |
0.425 |
|
| 2019 |
Call A, Casadevall C, Romero-Rivera A, Martin-Diaconescu V, Sommer DJ, Osuna S, Ghirlanda G, Lloret-Fillol J. Improved Electro- and Photocatalytic Water Reduction by Confined Cobalt Catalysts in Streptavidin Acs Catalysis. 9: 5837-5846. DOI: 10.1021/Acscatal.8B04981 |
0.315 |
|
| 2018 |
Korendovych IV, Ghirlanda G. Editorial overview: The many facets of protein design: from self-assembled materials to vaccines. Current Opinion in Structural Biology. 51: iv-vi. PMID 30401427 DOI: 10.1016/J.Sbi.2018.10.004 |
0.602 |
|
| 2018 |
Alcala-Torano R, Walther M, Sommer DJ, Park CK, Ghirlanda G. Rational design of a hexameric protein assembly stabilized by metal chelation. Biopolymers. e23233. PMID 30191549 DOI: 10.1002/Bip.23233 |
0.399 |
|
| 2017 |
Olson TL, Espiritu E, Edwardraja S, Canarie E, Flores M, Williams JC, Ghirlanda G, Allen JP. Biochemical and spectroscopic characterization of dinuclear Mn-sites in artificial four-helix bundle proteins. Biochimica Et Biophysica Acta. PMID 28882760 DOI: 10.1016/J.Bbabio.2017.08.013 |
0.36 |
|
| 2017 |
Dizicheh ZB, Halloran N, Asma W, Ghirlanda G. De Novo Design of Iron-Sulfur Proteins. Methods in Enzymology. 595: 33-53. PMID 28882205 DOI: 10.1016/Bs.Mie.2017.07.014 |
0.35 |
|
| 2017 |
Campitelli P, Zhou H, Ghirlanda G, Ozkan SB. Dynamic Flexibility Index Sheds Light on Pin1 Allostery Biophysical Journal. 112: 317a. DOI: 10.1016/J.Bpj.2016.11.1720 |
0.381 |
|
| 2016 |
Sommer DJ, Alcala-Torano R, Dizicheh ZB, Ghirlanda G. Design of Redox-Active Peptides: Towards Functional Materials. Advances in Experimental Medicine and Biology. 940: 215-243. PMID 27677515 DOI: 10.1007/978-3-319-39196-0_10 |
0.359 |
|
| 2016 |
Alcala-Torano R, Sommer DJ, Dizicheh ZB, Ghirlanda G. Design Strategies for Redox Active Metalloenzymes: Applications in Hydrogen Production. Methods in Enzymology. 580: 389-416. PMID 27586342 DOI: 10.1016/Bs.Mie.2016.06.001 |
0.423 |
|
| 2016 |
Woodrum BW, Maxwell J, Allen DM, Wilson J, Krumpe LR, Bobkov AA, Hill RB, Kibler KV, O'Keefe BR, Ghirlanda G. A Designed "Nested" Dimer of Cyanovirin-N Increases Antiviral Activity. Viruses. 8. PMID 27275831 DOI: 10.3390/V8060158 |
0.503 |
|
| 2015 |
Li Z, Bolia A, Maxwell JD, Bobkov AA, Ghirlanda G, Ozkan SB, Margulis CJ. A Rigid Hinge Region Is Necessary for High-Affinity Binding of Dimannose to Cyanovirin and Associated Constructs. Biochemistry. PMID 26507789 DOI: 10.1021/Acs.Biochem.5B00635 |
0.359 |
|
| 2015 |
Olson TL, Espiritu E, Edwardraja S, Simmons C, Williams JC, Ghirlanda G, Allen JP. Design of dinuclear manganese cofactors for bacterial reaction centers. Biochimica Et Biophysica Acta. PMID 26392146 DOI: 10.1016/J.Bbabio.2015.09.003 |
0.379 |
|
| 2015 |
Sommer DJ, Vaughn MD, Clark BC, Tomlin J, Roy A, Ghirlanda G. Reengineering cyt b562 for hydrogen production: A facile route to artificial hydrogenases. Biochimica Et Biophysica Acta. PMID 26375327 DOI: 10.1016/J.Bbabio.2015.09.001 |
0.331 |
|
| 2015 |
Sizemore SM, Cope SM, Roy A, Ghirlanda G, Vaiana SM. Slow Internal Dynamics and Charge Expansion in the Disordered Protein CGRP: A Comparison with Amylin. Biophysical Journal. 109: 1038-48. PMID 26331261 DOI: 10.1016/J.Bpj.2015.07.023 |
0.392 |
|
| 2015 |
Flores M, Olson TL, Wang D, Edwardraja S, Shinde S, Williams JC, Ghirlanda G, Allen JP. The Copper Environment in Artificial Metalloproteins Probed by EPR Spectroscopy. The Journal of Physical Chemistry. B. PMID 26201933 DOI: 10.1021/Acs.Jpcb.5B04172 |
0.686 |
|
| 2015 |
Sommer DJ, Roy A, Astashkin A, Ghirlanda G. Modulation of Cluster Incorporation Specificity in a De Novo Iron-Sulfur Cluster Binding Peptide. Biopolymers. PMID 25808361 DOI: 10.1002/Bip.22635 |
0.34 |
|
| 2014 |
Roy A, Sommer DJ, Schmitz RA, Brown CL, Gust D, Astashkin A, Ghirlanda G. A de novo designed 2[4Fe-4S] ferredoxin mimic mediates electron transfer. Journal of the American Chemical Society. 136: 17343-9. PMID 25437708 DOI: 10.1021/Ja510621E |
0.345 |
|
| 2014 |
Shinde S, Binder JK, Goyal B, Woodrum B, De Munari S, Levitus M, Ghirlanda G. A designed buried salt bridge modulates heterodimerization of a membrane peptide. Biopolymers. 102: 437-43. PMID 25250823 DOI: 10.1002/Bip.22564 |
0.7 |
|
| 2014 |
Flory JD, Simmons CR, Lin S, Johnson T, Andreoni A, Zook J, Ghirlanda G, Liu Y, Yan H, Fromme P. Low temperature assembly of functional 3D DNA-PNA-protein complexes. Journal of the American Chemical Society. 136: 8283-95. PMID 24871902 DOI: 10.1021/Ja501228C |
0.383 |
|
| 2014 |
Bolia A, Woodrum BW, Cereda A, Ruben MA, Wang X, Ozkan SB, Ghirlanda G. A flexible docking scheme efficiently captures the energetics of glycan-cyanovirin binding Biophysical Journal. 106: 1142-1151. PMID 24606938 DOI: 10.1016/J.Bpj.2014.01.040 |
0.597 |
|
| 2014 |
Cope SM, Sizemore SM, Roy A, Ghirlanda G, Vaiana SM. Structure and Internal Dynamics of Calcitonin Family Peptides: Implications for Amyloid Formation Biophysical Journal. 106: 687a. DOI: 10.1016/J.Bpj.2013.11.3802 |
0.411 |
|
| 2014 |
Sizemore SM, Cope SM, Roy A, Ghirlanda G, Vaiana SM. Solvent Effects on the Structure and Internal Dynamics of Calcitonin Gene-Related Peptide Biophysical Journal. 106: 271a. DOI: 10.1016/J.Bpj.2013.11.1588 |
0.372 |
|
| 2013 |
Faiella M, Roy A, Sommer D, Ghirlanda G. De novo design of functional proteins: Toward artificial hydrogenases. Biopolymers. 100: 558-71. PMID 24281721 DOI: 10.1002/Bip.22420 |
0.391 |
|
| 2013 |
Cope SM, Shinde S, Best RB, Ghirlanda G, Vaiana SM. Cyclic N-terminal loop of amylin forms non amyloid fibers. Biophysical Journal. 105: 1661-9. PMID 24094407 DOI: 10.1016/J.Bpj.2013.08.026 |
0.65 |
|
| 2013 |
Roy A, Sarrou I, Vaughn MD, Astashkin AV, Ghirlanda G. De novo design of an artificial bis[4Fe-4S] binding protein. Biochemistry. 52: 7586-94. PMID 24090184 DOI: 10.1021/Bi401199S |
0.379 |
|
| 2013 |
Woodrum BW, Maxwell JD, Bolia A, Ozkan SB, Ghirlanda G. The antiviral lectin cyanovirin-N: probing multivalency and glycan recognition through experimental and computational approaches. Biochemical Society Transactions. 41: 1170-6. PMID 24059504 DOI: 10.1042/Bst20130154 |
0.352 |
|
| 2013 |
Ghirlanda G. Computational biology: A recipe for ligand-binding proteins. Nature. 501: 177-8. PMID 24005323 DOI: 10.1038/Nature12463 |
0.396 |
|
| 2013 |
Flory JD, Shinde S, Lin S, Liu Y, Yan H, Ghirlanda G, Fromme P. PNA-peptide assembly in a 3D DNA nanocage at room temperature. Journal of the American Chemical Society. 135: 6985-93. PMID 23521013 DOI: 10.1021/Ja400762C |
0.677 |
|
| 2013 |
Cope SM, Sizemore SM, Roy A, Ghirlanda G, Vaiana SM. Effect of Prolines on the Intrinsic Stiffness of Islet Amyloid Polypeptide Variants Biophysical Journal. 104: 57a. DOI: 10.1016/J.Bpj.2012.11.352 |
0.358 |
|
| 2013 |
Sizemore SM, Cope SM, Roy A, Ghirlanda G, Vaiana SM. Electrostatic Interactions Modulate the Structure and Dynamics of Calcitonin Gene-Related Peptide Biophysical Journal. 104: 54a-55a. DOI: 10.1016/J.Bpj.2012.11.342 |
0.4 |
|
| 2013 |
Zou T, Woodrum B, Ghirlanda G, Sefika Ozkan B. Deciphering the Protein Folding Code through Zipping Steps Biophysical Journal. 104: 398a. DOI: 10.1016/J.Bpj.2012.11.2220 |
0.385 |
|
| 2013 |
Bolia A, Woodrum B, Ozkan B, Ghirlanda G. Reengineering the Oligosaccharide Specificity of CVN with BP_Dock Biophysical Journal. 104: 379a-380a. DOI: 10.1016/J.Bpj.2012.11.2114 |
0.416 |
|
| 2013 |
Ghirlanda G, Senes A. Preface Methods in Molecular Biology. 1063: V-VI. |
0.536 |
|
| 2012 |
Guarise C, Shinde S, Kibler K, Ghirlanda G, Prins LJ, Scrimin P. A multivalent HIV-1 fusion inhibitor based on small helical foldamers. Tetrahedron. 68: 4346-4352. PMID 32287423 DOI: 10.1016/J.Tet.2012.03.078 |
0.664 |
|
| 2012 |
Roy A, Madden C, Ghirlanda G. Photo-induced hydrogen production in a helical peptide incorporating a [FeFe] hydrogenase active site mimic. Chemical Communications (Cambridge, England). 48: 9816-8. PMID 22895256 DOI: 10.1039/C2Cc34470J |
0.359 |
|
| 2012 |
Shinde S, Cordova JM, Woodrum BW, Ghirlanda G. Modulation of function in a minimalist heme-binding membrane protein. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 17: 557-64. PMID 22307279 DOI: 10.1007/S00775-012-0876-1 |
0.69 |
|
| 2012 |
Cope SM, Shinde S, Ghirlanda G, Vaiana SM. Effect of a Single-Point Mutation on the Conformation and Dynamics of Islet Amyloid Polypeptide from Nanosecond-Resolved Intramolecular Contact Formation Biophysical Journal. 102: 632a. DOI: 10.1016/J.Bpj.2011.11.3440 |
0.673 |
|
| 2012 |
Binder JK, Shinde S, Woodrum B, Ghirlanda G, Levitus M. Monitoring Dimerization of GpA using FRET Biophysical Journal. 102: 267a. DOI: 10.1016/J.Bpj.2011.11.1467 |
0.691 |
|
| 2012 |
Sizemore SM, Cope SM, Shinde S, Ghirlanda G, Vaiana SM. Transient Tertiary Contact Formation in the CGRP Neuropeptide Revealed by Nanosecond Laser Spectroscopy Biophysical Journal. 102: 10a. DOI: 10.1016/J.Bpj.2011.11.077 |
0.685 |
|
| 2011 |
Halsey CM, Xiong J, Oshokoya OO, Johnson JA, Shinde S, Beatty JT, Ghirlanda G, JiJi RD, Cooley JW. Simultaneous observation of peptide backbone lipid solvation and α-helical structure by deep-UV resonance Raman spectroscopy. Chembiochem : a European Journal of Chemical Biology. 12: 2125-8. PMID 21796753 DOI: 10.1002/Cbic.201100433 |
0.659 |
|
| 2009 |
Ghirlanda G. Design of membrane proteins: toward functional systems. Current Opinion in Chemical Biology. 13: 643-51. PMID 19828358 DOI: 10.1016/J.Cbpa.2009.09.017 |
0.376 |
|
| 2009 |
Liu Y, Carroll JR, Holt LA, McMahon J, Giomarelli B, Ghirlanda G. Multivalent interactions with gp120 are required for the anti-HIV activity of Cyanovirin. Biopolymers. 92: 194-200. PMID 19235857 DOI: 10.1002/Bip.21173 |
0.376 |
|
| 2008 |
Fromme R, Katiliene Z, Fromme P, Ghirlanda G. Conformational gating of dimannose binding to the antiviral protein cyanovirin revealed from the crystal structure at 1.35 A resolution. Protein Science : a Publication of the Protein Society. 17: 939-44. PMID 18436959 DOI: 10.1110/Ps.083472808 |
0.421 |
|
| 2008 |
Spiriti J, Bogani F, van der Vaart A, Ghirlanda G. Modulation of protein stability by O-glycosylation in a designed Gc-MAF analog. Biophysical Chemistry. 134: 157-67. PMID 18329161 DOI: 10.1016/J.Bpc.2008.02.005 |
0.664 |
|
| 2007 |
Fromme R, Katiliene Z, Giomarelli B, Bogani F, Mc Mahon J, Mori T, Fromme P, Ghirlanda G. A monovalent mutant of cyanovirin-N provides insight into the role of multiple interactions with gp120 for antiviral activity. Biochemistry. 46: 9199-207. PMID 17636873 DOI: 10.1021/Bi700666M |
0.635 |
|
| 2007 |
Cordova JM, Noack PL, Hilcove SA, Lear JD, Ghirlanda G. Design of a functional membrane protein by engineering a heme-binding site in glycophorin A. Journal of the American Chemical Society. 129: 512-8. PMID 17227013 DOI: 10.1021/Ja057495I |
0.461 |
|
| 2006 |
Bogani F, McConnell E, Joshi L, Chang Y, Ghirlanda G. A designed glycoprotein analogue of Gc-MAF exhibits native-like phagocytic activity. Journal of the American Chemical Society. 128: 7142-3. PMID 16734450 DOI: 10.1021/Ja0604212 |
0.676 |
|
| 2004 |
Ghirlanda G, Hilcove SA, Pidikiti R, Johansson JS, Lear JD, Degrado WF, Eckenhoff RG. Volatile anesthetic modulation of oligomerization equilibria in a hexameric model peptide. Febs Letters. 578: 140-4. PMID 15581631 DOI: 10.1016/J.Febslet.2004.10.087 |
0.541 |
|
| 2004 |
Ghirlanda G, Osyczka A, Liu W, Antolovich M, Smith KM, Dutton PL, Wand AJ, DeGrado WF. De novo design of a D2-symmetrical protein that reproduces the diheme four-helix bundle in cytochrome bc1. Journal of the American Chemical Society. 126: 8141-7. PMID 15225055 DOI: 10.1021/Ja039935G |
0.598 |
|
| 2002 |
Ghirlanda G, Lear JD, Ogihara NL, Eisenberg D, DeGrado WF. A hierarchic approach to the design of hexameric helical barrels. Journal of Molecular Biology. 319: 243-53. PMID 12051949 DOI: 10.1016/S0022-2836(02)00233-4 |
0.58 |
|
| 2001 |
Tang Y, Ghirlanda G, Petka WA, Nakajima T, DeGrado WF, Tirrell DA. Fluorinated Coiled-Coil Proteins Prepared In Vivo Display Enhanced Thermal and Chemical Stability. Angewandte Chemie (International Ed. in English). 40: 1494-1496. PMID 29712367 DOI: 10.1002/1521-3773(20010417)40:8<1494::Aid-Anie1494>3.0.Co;2-X |
0.524 |
|
| 2001 |
North B, Summa CM, Ghirlanda G, DeGrado WF. D(n)-symmetrical tertiary templates for the design of tubular proteins. Journal of Molecular Biology. 311: 1081-90. PMID 11531341 DOI: 10.1006/Jmbi.2001.4900 |
0.722 |
|
| 2001 |
Tang Y, Ghirlanda G, Petka WA, Nakajima T, DeGrado WF, Tirrell DA. Fluorinated Coiled-Coil Proteins Prepared In Vivo Display Enhanced Thermal and Chemical Stability This work was supported by a grant from the U.S. Army Research Office. Y. Tang is supported by a Whitaker Graduate Research Fellowship. We thank Dr. Gary Hathaway for performing matrix-assisted laser desorption/ionization analyses. Angewandte Chemie (International Ed. in English). 40: 1494-1496. PMID 11317312 DOI: 10.1002/1521-3773(20010417)40:8<1494::AID-ANIE1494>3.0.CO;2-X |
0.371 |
|
| 2001 |
Tang Y, Ghirlanda G, Vaidehi N, Kua J, Mainz DT, Goddard III WA, DeGrado WF, Tirrell DA. Stabilization of coiled-coil peptide domains by introduction of trifluoroleucine. Biochemistry. 40: 2790-6. PMID 11258889 DOI: 10.1021/Bi0022588 |
0.573 |
|
| 2001 |
Ogihara NL, Ghirlanda G, Bryson JW, Gingery M, DeGrado WF, Eisenberg D. Design of three-dimensional domain-swapped dimers and fibrous oligomers. Proceedings of the National Academy of Sciences of the United States of America. 98: 1404-9. PMID 11171963 DOI: 10.1073/Pnas.98.4.1404 |
0.533 |
|
| 1998 |
Ghirlanda G, Lear JD, Lombardi A, Degrado WF. From synthetic coiled coils to functional proteins: Automated design of a receptor for the calmodulin-binding domain of calcineurin Journal of Molecular Biology. 281: 379-391. PMID 9698554 DOI: 10.1006/Jmbi.1998.1912 |
0.498 |
|
| 1998 |
Ghirlanda G, Scrimin P, Tecilla P, Toffoletti A. Amphiphilic copper(II) complexes modeled after the metal-complexation subunit of bleomycin antibiotics Langmuir. 14: 1646-1655. DOI: 10.1021/La971156O |
0.313 |
|
| 1997 |
Lombardi A, Bryson JW, Ghirlanda G, DeGrado WF. Design of a Synthetic Receptor for the Calmodulin-Binding Domain of Calcineurin Journal of the American Chemical Society. 119: 12378-12379. DOI: 10.1021/Ja972973D |
0.5 |
|
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